Hepatitis, Alcoholic: INFLAMMATION of the LIVER due to ALCOHOL ABUSE. It is characterized by NECROSIS of HEPATOCYTES, infiltration by NEUTROPHILS, and deposit of MALLORY BODIES. Depending on its severity, the inflammatory lesion may be reversible or progress to LIVER CIRRHOSIS.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
311 |
4. Check minimum number of eventsNone |
311 |
5. Include endpointsNone |
311 |
6. Filter based on genotype QC (FinnGen only) |
294 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- K73
Similar endpoints
↥List of similar endpoints to
Nonalcoholic steatohepatitis
based on the number of shared cases.
Similar with more cases:
- Chronic hepatitis, not elsewhere classified
- Diseases of liver
- Gastrointestinal diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1036 | 555 | 476 |
| Only index persons | 1025 | 553 | 472 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 56.00 | 59.82 | 51.78 |
| Only index persons | 56.32 | 60.05 | 51.94 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 294 | 167 | 127 |
| Unadjusted period prevalence (%) | 0.06 | 0.06 | 0.06 |
| Median age at first event (years) | 59.34 | 59.47 | 59.16 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 311
- Matched controls
- 3110
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K73.80
ICD-10 Finland
Non-alcoholic fatty liver (NASH, Non Alcoholic Steatohepatitis)
+∞
307.7
311
*
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
69.2
236.6
137
35
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
70.5
185.0
104
22
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
52.9
102.5
60
14
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
11.3
81.9
104
132
A10BG03
ATC
pioglitazone; oral
32.1
73.3
49
18
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
10.8
65.7
82
100
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
6.5
59.4
152
401
215
Kela drug reimbursment
Diabetes, non-insulin-treated
6.2
57.8
162
462
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
10.2
57.1
73
91
103
Kela drug reimbursment
Diabetes, insulin-treated
6.0
55.9
162
474
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
20.1
52.4
42
24
A10BJ06
ATC
semaglutide; parenteral
10.1
51.6
65
79
A10BA02
ATC
metformin; oral
5.5
50.1
164
523
T90
ICPC
Diabetes non-insulin dependent
5.3
46.3
145
441
E66.00
ICD-10 Finland
Metabolic syndrome
9.0
44.5
61
82
A10BH01
ATC
sitagliptin; oral
6.9
43.1
78
143
E66.01
ICD-10 Finland
Obesity due to excess calories
6.5
41.2
81
161
E66.8
ICD-10 Finland
Other obesity
7.8
34.8
53
80
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.2
34.0
148
556
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
6.0
33.7
69
141
A10AE04
ATC
insulin glargine; parenteral
5.9
33.7
70
145
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.9
30.4
81
208
A10BH05
ATC
linagliptin; oral
9.1
30.2
39
48
C03DA01
ATC
spironolactone; oral
5.1
28.5
70
167
160
Kela drug reimbursment
exenatide
10.6
26.3
30
31
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
36.7
23.8
30
9
A10BJ02
ATC
liraglutide; parenteral
8.0
22.5
32
44
K76.9
ICD-10 Finland
Liver disease, unspecified
19.7
21.4
32
18
E11
ICD-10 Finland
Type 2 diabetes mellitus
3.7
20.9
83
280
A10BK03
ATC
empagliflozin; oral
4.2
20.4
62
173
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
8.6
20.3
27
34
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
38.6
20.2
25
7
SPAT1262
SPAT
Handing over of treatment supplies
3.6
19.9
83
289
A10BK01
ATC
dapagliflozin; oral
4.8
19.6
48
113
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
3.0
18.0
108
465
A07AA11
ATC
rifaximin; oral
+∞
17.9
17
*
G47.3
ICD-10 Finland
Sleep apnoea
3.0
17.7
112
495
205
Kela drug reimbursment
Chronic hypertension
3.1
16.7
93
381
I10
ICD-10 Finland
Essential (primary) hypertension
2.8
16.1
208
1310
Z01.8
ICD-10 Finland
Other specified special examinations
2.9
15.8
100
439
JN3AD
NOMESCO Finland
Abdominal CT examination
3.6
14.7
54
171
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
23.6
14.4
20
9
A10AB05
ATC
insulin aspart; parenteral
4.1
14.2
42
114
C03CA01
ATC
furosemide; systemic
2.8
14.1
89
387
N02AX02
ATC
tramadol; systemic, rectal
2.5
14.0
164
962
E66.9
ICD-10 Finland
Obesity, unspecified
5.7
14.0
27
51
R18
ICD-10 Finland
Ascites
14.5
14.0
23
17
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.4
13.7
36
89
R94.5
ICD-10 Finland
Abnormal results of liver function studies
14.7
13.5
22
16
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
13.2
89
399
A10BX04
ATC
[U] exenatide
23.8
13.0
18
8
T82
ICPC
Obesity
5.1
12.9
28
59
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
9.9
12.2
24
26
R4190
NOMESCO Finland
Nutritional therapy
5.2
12.1
26
54
A10BJ05
ATC
dulaglutide; parenteral
9.5
12.0
24
27
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
8.9
11.5
24
29
A10AC01
ATC
insulin (human); parenteral
3.8
11.4
37
107
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
3.0
11.4
55
205
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
5.3
11.2
23
46
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
10.9
134
781
H02AB04
ATC
methylprednisolone; systemic
2.9
10.8
58
229
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.2
10.8
46
159
UJF32
NOMESCO Finland
Coloscopy
2.4
10.7
94
473
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
2.4
10.4
92
463
A10BD07
ATC
metformin and sitagliptin; systemic
4.8
10.4
24
53
XW000
NOMESCO Finland
Bone marrow biopsy
5.2
10.4
22
45
K74.0
ICD-10 Finland
Hepatic fibrosis
33.8
10.4
13
*
E66
ICD-10 Finland
Obesity
3.8
10.1
32
91
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.9
10.0
54
213
J01MA02
ATC
ciprofloxacin; systemic
2.2
10.0
132
785
R03AC02
ATC
salbutamol; inhalant
2.2
9.8
195
1355
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
56.8
9.7
11
*
UJF30
NOMESCO Finland
Ileoscopy through colon
3.0
9.7
46
169
L04AX01
ATC
azathioprine; systemic
5.0
9.7
21
44
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
9.5
153
976
K73.89
ICD-10 Finland
Other long-term hepatitis, not classified differently
+∞
9.4
9
*
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
8.1
9.3
20
26
M01AB01
ATC
indometacin; systemic, rectal
3.8
9.2
29
82
C08CA13
ATC
lercanidipine; oral
2.7
9.2
53
217
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.1
9.0
40
141
J45.9
ICD-10 Finland
Asthma, unspecified
2.4
9.0
74
359
D07AC01
ATC
betamethasone; topical
2.1
9.0
128
777
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
8.9
42
154
C08CA01
ATC
amlodipine; oral
2.1
8.7
120
718
D64.9
ICD-10 Finland
Anaemia, unspecified
3.2
8.7
36
122
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.4
8.6
73
359
UJF92
NOMESCO Finland
Capsular endoscopy
8.2
8.5
18
23
C07AG02
ATC
carvedilol; oral
3.8
8.5
26
72
C09BA02
ATC
enalapril and diuretics; systemic
3.4
8.5
31
97
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.3
8.4
33
108
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.7
8.3
49
202
WX892
NOMESCO Finland
Monitored bed care
3.3
8.3
33
109
UKC02
NOMESCO Finland
Cystoscopy
2.6
8.2
51
216
A10BX07
ATC
[U] liraglutide
10.4
8.1
15
15
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.6
8.1
52
224
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
22.7
8.1
11
5
J01FF01
ATC
clindamycin; systemic
2.1
8.0
97
549
K29.7
ICD-10 Finland
Gastritis, unspecified
4.7
7.8
18
40
Z94.4
ICD-10 Finland
Liver transplant status
46.2
7.8
9
*
N06AX11
ATC
mirtazapine; oral
2.0
7.7
119
734
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.8
7.6
41
161
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
25.7
7.6
10
*
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
25.7
7.6
10
*
P06
ICPC
Sleep disturbance
2.5
7.5
51
225
N03AX16
ATC
[U] pregabalin
2.1
7.5
83
453
M01AE03
ATC
ketoprofen; systemic, rectal
2.0
7.5
125
792
JJC00
NOMESCO Finland
Allogenic transplantation of liver
82.0
7.4
8
*
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
82.0
7.4
8
*
J01DB01
ATC
cefalexin; oral
2.5
7.4
270
2245
D07XC01
ATC
betamethasone; topical
2.5
7.3
49
215
K73.8
ICD-10 Finland
Other chronic hepatitis, not elsewhere classified
+∞
7.3
7
*
K72.1
ICD-10 Finland
Chronic hepatic failure
+∞
7.3
7
*
WX002
NOMESCO Finland
Sedation and analgesia
2.2
7.3
69
353
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.6
7.3
24
70
A10AE05
ATC
insulin detemir; parenteral
3.6
7.3
24
70
C09AA02
ATC
enalapril; systemic
2.3
7.3
61
297
R29
ICPC
Respiratory symptom/complaint other
3.1
7.2
31
107
E83.1
ICD-10 Finland
Disorders of iron metabolism
20.6
7.2
10
5
A02BC02
ATC
pantoprazole; systemic
2.0
7.1
216
1659
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
9.1
7.1
14
16
A10BB12
ATC
glimepiride; oral
3.6
7.0
23
67
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.2
7.0
67
345
WX725
NOMESCO Finland
Noninvasive ventilation
3.3
6.9
27
88
R5140
NOMESCO Finland
Monitoring the use of the aid
2.5
6.9
48
215
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.4
6.8
17
40
D97
ICPC
Liver disease NOS
17.2
6.8
10
6
JJA20
NOMESCO Finland
Open biopsy of liver
41.0
6.8
8
*
C09DA01
ATC
losartan and diuretics; oral
2.6
6.7
42
178
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
3.4
6.7
25
79
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
6.7
6.7
16
25
162
Kela drug reimbursment
liraglutide
8.1
6.7
14
18
H02AB07
ATC
prednisone; oral
2.4
6.7
50
231
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
9.0
6.6
13
15
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.8
6.6
20
55
N06AB10
ATC
escitalopram; oral
2.1
6.6
76
420
WX110
NOMESCO Finland
Infiltration anesthesia
2.0
6.4
234
1879
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
2.5
6.4
44
196
A10BJ01
ATC
exenatide; parenteral
11.3
6.3
11
10
H02AB06
ATC
prednisolone; systemic
1.8
6.3
150
1050
K70.0
ICD-10 Finland
Alcoholic fatty liver
18.5
6.3
9
5
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
+∞
6.3
6
*
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
3.5
6.3
22
67
K72.9
ICD-10 Finland
Hepatic failure, unspecified
27.3
6.3
8
*
M04AA01
ATC
allopurinol; systemic
2.5
6.2
41
178
A46
ICD-10 Finland
Erysipelas
2.4
6.2
46
212
L04AD02
ATC
tacrolimus; systemic
12.9
6.1
10
8
127
Kela drug reimbursment
Transplant complication
8.9
6.1
12
14
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.4
6.0
43
194
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
164
179
18.27
150.58
1.5
1.6
1.28
1.61
g/l
0.68
150
164
171
214
16.53
142.70
2.1
2.6
11.11
10.27
g/l
1.55
156
198
168
229
14.78
130.78
3.7
2.3
0.22
0.23
g/l
0.14
158
213
190
314
13.98
127.70
2.5
2.3
2.53
2.40
g/l
1.74
183
292
182
295
13.46
123.61
2.6
2.3
24.73
24.63
%
0.02
150
259
187
350
11.89
111.47
2.6
2.3
14.48
14.40
umol/l
0.05
182
328
71
24
38.04
110.32
1.2
1.2
—
—
—
0
0
154
307
8.96
83.41
4.4
2.5
8.83
7.93
umol/l
0.19
141
269
269
1012
13.28
77.17
10.4
4.8
36.60
36.03
g/l
0.93
258
953
150
376
6.77
62.35
2.0
1.7
1.52
1.45
%
0.58
132
327
174
551
5.90
54.53
1.9
1.4
3.09
2.30
g/l
4.10
138
340
242
1093
6.47
47.85
13.2
9.5
1.08
1.15
inr
1.01
67
319
234
1080
5.71
43.47
4.3
2.6
221.48
109.35
ug/l
5.48
223
1006
182
735
4.56
38.92
4.9
3.7
5.99
8.20
mg/mmol
0.45
134
455
159
602
4.36
36.63
1.4
1.3
1.01
2.06
u/ml
0.81
29
168
182
765
4.32
36.13
4.3
3.0
7.72
7.86
mmol/l
0.16
162
657
147
530
4.36
36.13
2.7
2.0
3.09
3.04
mg/l
0.07
129
453
31
25
13.66
31.97
1.1
1.0
—
—
—
0
0
177
827
3.65
28.05
5.2
2.5
50.33
58.46
u/l
1.97
168
773
288
1898
8.00
27.38
9.7
3.0
140.93
47.38
u/l
11.04
278
1797
44
74
6.76
25.90
1.3
1.3
—
—
—
0
0
182
932
3.30
23.62
2.5
1.8
95.64
97.91
pmol/l
0.21
103
453
246
1518
3.97
23.40
10.8
9.6
4.06
3.99
e9/l
0.18
213
1329
218
1252
3.48
23.15
8.8
5.6
56.17
56.55
%
0.18
209
1184
220
1271
3.50
23.12
8.8
5.8
28.37
28.66
%
0.15
211
1204
192
1026
3.28
22.96
2.9
2.2
68.17
76.28
nmol/l
3.87
173
925
27
8
36.77
21.50
1.1
1.0
—
—
—
0
0
205
1177
3.18
20.92
10.2
7.0
1.21
1.22
mmol/l
1.13
186
1017
194
1099
3.03
19.92
7.2
5.9
1.21
1.22
mmol/l
1.36
185
1010
98
406
3.06
17.37
3.3
3.6
0.79
0.82
mmol/l
1.50
90
386
224
1447
2.96
16.79
6.8
4.8
7.99
6.61
mmol/l
8.21
218
1355
131
667
2.67
15.44
3.5
2.5
372.38
5464.71
umol/l
2.37
120
590
21
10
22.40
14.86
2.4
2.8
44071.43
34080.50
ug/l
—
21
10
25
42
6.39
14.56
1.3
1.5
—
—
—
0
0
302
2571
7.03
13.73
7.7
4.2
6.87
5.89
mmol/l
13.02
289
2389
24
43
5.96
13.10
8.0
7.6
180.17
111.63
iu/ml
—
6
8
34
84
4.42
12.94
2.7
2.1
1.16
1.55
g/l
1.38
28
72
106
526
2.54
12.74
1.7
1.4
20.17
22.18
nmol/l
0.75
97
440
133
734
2.42
12.67
2.0
1.7
1.80
1.44
mmol/l
2.92
115
631
26
52
5.36
12.65
1.2
1.2
—
—
—
0
0
113
581
2.48
12.56
3.2
2.2
—
—
—
0
0
179
1152
2.30
11.64
4.3
2.5
—
—
—
0
0
130
732
2.33
11.61
2.8
2.0
191.89
310.24
u/l
0.56
124
693
25
54
4.95
11.15
1.6
2.0
—
—
—
0
0
24
50
5.12
11.15
1.3
1.2
364.85
224.21
u/ml
0.98
13
29
46
156
3.29
11.12
2.5
1.5
—
—
—
0
0
39
119
3.60
11.10
2.3
2.5
61.62
41.29
u/l
3.03
34
108
89
433
2.48
10.95
1.6
1.6
357143288.92
19677004.34
pmol/l
0.87
77
371
259
1997
2.78
10.69
4.9
3.9
14.39
14.65
pmol/l
1.07
241
1829
41
134
3.37
10.50
5.4
3.3
0.03
1.86
mmol/l
1.52
31
100
250
1905
2.59
10.39
6.9
3.9
15.63
10.32
mm/h
6.09
234
1764
302
2658
5.70
10.33
6.3
4.3
4.43
4.80
mmol/l
9.08
288
2496
75
351
2.50
9.93
2.1
2.0
—
—
—
0
0
138
840
2.16
9.80
4.7
2.9
—
—
—
0
0
290
2419
3.94
9.62
6.4
4.5
1.96
2.34
mu/l
0.36
276
2233
22
50
4.66
9.24
1.2
1.4
99.60
86.43
u/ml
—
5
7
59
256
2.61
9.09
3.0
2.2
29.82
34.17
u/l
0.34
50
218
107
613
2.14
8.67
2.9
2.9
865.22
735.25
ng/l
0.17
80
506
46
180
2.83
8.64
1.7
2.9
68.35
67.59
g/l
0.27
41
169
74
372
2.30
8.23
2.1
1.5
1050.80
1182.53
nmol/l
0.54
59
282
20
32
6.60
8.16
2.6
4.1
—
1305.00
—
0
5
177
1240
1.99
8.07
4.5
3.1
0.00
0.00
estimate
0.50
28
254
177
1242
1.99
8.01
6.1
4.3
0.00
0.00
estimate
-0.00
27
240
296
2563
4.21
7.95
5.5
3.8
1.76
1.32
mmol/l
8.54
282
2382
31
101
3.30
7.95
2.8
3.4
35.44
1442.15
u/ml
0.53
25
88
23
61
3.99
7.95
1.9
1.4
—
—
—
0
0
177
1257
1.95
7.57
4.6
3.2
0.04
0.01
estimate
0.29
24
229
18
42
4.49
7.32
2.2
1.6
—
—
—
0
0
300
2648
4.76
7.24
6.4
4.2
1.20
1.48
mmol/l
29.74
287
2471
52
246
2.34
6.58
2.1
1.9
—
—
—
0
0
29
103
3.00
6.46
1.2
2.1
—
—
—
0
0
106
664
1.90
6.37
3.9
2.8
0.34
0.35
e6/l
0.03
78
486
289
2528
3.02
6.37
23.6
11.2
86.10
85.45
ml/min/173m2
0.18
245
2047
56
278
2.24
6.32
6.4
7.6
103.59
104.39
mmol/l
0.71
56
278
72
403
2.02
5.95
3.0
2.5
1.13
0.89
e6/l
0.22
41
224
68
381
2.00
5.58
3.4
2.6
3.09
2.18
e6/l
0.54
39
203
81
483
1.92
5.55
1.3
1.3
42.00
29.95
iu/ml
0.35
24
174
13
21
6.41
5.44
1.0
1.0
—
—
—
0
0
20
64
3.27
5.29
1.9
2.5
86.35
98.51
ug/min
0.09
13
37
50
255
2.14
5.26
2.2
1.9
—
—
—
0
0
311
2979
+∞
5.20
41.8
18.2
40.83
40.94
%
0.13
298
2808
56
301
2.05
5.13
6.5
4.1
28.17
32.39
%
1.60
47
198
119
822
1.73
4.94
3.2
3.5
2.36
2.36
mmol/l
0.24
102
734
8
8
10.22
4.54
1.0
1.0
13.97
9.41
ug/l
—
8
8
85
548
1.76
4.44
2.4
1.7
1.20
1.01
mg/l
0.21
71
433
23
90
2.68
4.33
9.1
10.9
1.89
1.61
%
0.99
23
82
10
16
6.42
4.33
2.2
1.5
—
—
—
0
0
8
9
9.08
4.30
1.0
1.7
—
—
—
0
0
8
9
9.08
4.30
1.0
1.7
—
—
—
0
0
47
254
2.00
4.23
6.9
10.0
1.00
1.21
mmol/l
0.11
37
203
47
256
1.98
4.14
7.0
9.9
5.06
5.17
kpa
0.38
47
244
47
256
1.98
4.14
7.0
9.9
11.87
12.39
kpa
0.28
47
245
14
36
4.02
4.05
1.6
1.5
—
—
—
0
0
7
7
10.19
4.03
1.0
1.0
—
—
—
0
0
10
18
5.70
4.00
1.0
1.3
—
—
—
0
0
11
23
4.92
3.91
1.1
1.1
—
—
—
0
0
20
77
2.71
3.89
1.8
1.9
—
—
—
0
0
20
77
2.71
3.89
1.2
1.3
344.56
306.61
ug/g
—
9
45
26
116
2.35
3.76
1.7
1.7
—
—
—
0
0
20
79
2.64
3.71
1.8
2.2
—
—
—
0
0
18
68
2.75
3.63
1.2
1.2
—
—
—
0
0
121
894
1.58
3.62
4.3
3.2
20.15
30.21
ng/l
1.18
90
577
13
36
3.72
3.54
1.6
1.5
—
—
—
0
0
13
36
3.72
3.54
1.6
1.5
—
—
—
0
0
82
554
1.65
3.53
5.1
3.4
1.02
1.02
kg/l
0.80
15
78
17
64
2.75
3.45
1.4
1.2
—
—
—
0
0
13
37
3.62
3.44
1.6
1.5
—
—
—
0
0
13
37
3.62
3.44
1.6
1.5
—
—
—
0
0
128
968
1.55
3.42
4.7
3.2
—
—
—
0
0
39
213
1.95
3.41
7.8
11.2
115.79
123.60
g/l
1.39
39
206
71
470
1.66
3.29
1.4
1.3
11.26
9.80
u/ml
0.07
19
186
9
19
4.84
3.26
5.1
2.2
—
—
—
0
0
16
61
2.71
3.18
1.9
2.9
24.47
25.24
mmol/l
0.35
16
61
35
190
1.95
3.12
1.4
1.2
147.13
167.31
iu/ml
0.15
15
74
8
16
5.10
3.07
4.6
1.7
67.38
100.31
%
—
8
16
12
36
3.43
3.05
1.7
1.5
—
—
—
0
0
12
38
3.24
2.88
1.0
1.1
—
—
—
0
0
6
9
6.77
2.88
1.0
1.7
—
—
—
0
0
6
9
6.77
2.88
1.0
1.7
—
—
—
0
0
36
204
1.86
2.84
1.6
2.6
81.67
68.23
ml/min/173m2
0.96
15
90
6
10
6.09
2.71
1.3
3.8
178.33
205.80
u/l
—
6
10
27
141
2.00
2.70
6.7
11.0
23.41
24.79
mmol/l
1.35
27
131
16
67
2.46
2.68
1.9
4.0
34.39
41.12
mg/l
0.37
16
55
16
67
2.46
2.68
2.0
4.0
24.87
26.91
mg/l
0.19
16
55
68
468
1.58
2.67
3.8
3.7
56.30
190.65
ng/l
1.02
50
342
5
7
7.24
2.56
1.4
1.0
-1.76
2.67
mmol/l
—
5
7
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
14
57
2.52
2.48
2.9
2.3
0.36
0.32
u/ml
—
9
31
16
70
2.36
2.45
2.0
1.6
—
—
—
0
0
204
1768
1.45
2.45
3.4
3.2
—
—
—
0
0
15
64
2.41
2.42
1.4
1.3
—
—
—
0
0
15
65
2.37
2.35
1.1
1.1
—
—
—
0
0
6
13
4.68
2.28
1.5
1.2
—
—
—
0
0
88
663
1.46
2.24
5.1
3.4
0.00
0.00
estimate
-0.00
27
237
24
129
1.93
2.24
1.3
1.3
—
—
—
0
0
11
41
2.74
2.23
1.0
1.5
—
—
—
0
0
11
41
2.74
2.23
1.0
1.5
—
—
—
0
0
31
183
1.77
2.18
1.5
1.3
128.43
311.81
u/ml
0.72
31
165
9
30
3.06
2.16
1.2
1.1
—
—
—
0
0
6
15
4.06
2.05
1.7
3.7
1467.50
650.53
u/ml
—
6
15
15
72
2.14
1.89
1.7
2.8
—
—
—
0
0
14
66
2.17
1.85
2.0
4.0
—
2.92
—
0
9
5
12
4.22
1.83
1.0
1.2
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
18
3.38
1.75
1.0
1.2
—
—
—
0
0
5
13
3.89
1.72
1.6
4.3
—
—
—
0
0
6
21
2.89
1.51
1.3
2.5
—
—
—
0
0
5
16
3.16
1.44
1.2
1.1
—
—
—
0
0
14
74
1.93
1.41
1.5
1.1
—
—
—
0
0
11
53
2.11
1.40
1.3
1.7
4126.00
23219.75
e6/l
—
6
36
7
29
2.45
1.40
1.3
1.1
—
—
—
0
0
91
742
1.32
1.39
4.5
4.1
1.51
2.17
ug/l
0.59
83
677
14
75
1.91
1.36
1.5
1.1
—
—
—
0
0
18
107
1.72
1.29
3.1
1.7
—
—
—
0
0
6
25
2.43
1.25
1.7
1.9
—
—
—
0
0
6
25
2.43
1.25
1.3
1.1
—
—
—
0
0
15
86
1.78
1.21
1.9
1.6
—
—
—
0
0
23
151
1.56
1.15
1.5
1.3
—
—
—
0
0
54
421
1.34
1.12
2.6
3.0
2.45
2.45
mmol/l
0.10
44
368
19
121
1.61
1.08
1.4
1.3
13.59
27.88
iu/l
1.87
14
99
9
49
1.86
0.99
1.0
1.3
—
—
—
0
0
9
49
1.86
0.99
1.9
1.8
—
—
—
0
0
5
23
2.19
0.98
1.2
1.5
—
—
—
0
0
22
150
1.50
0.96
2.8
2.6
24.08
53.46
u/ml
0.99
22
144
15
94
1.63
0.92
2.2
3.7
0.56
0.63
%
0.41
15
94
6
29
2.09
0.90
1.7
1.8
—
—
—
0
0
6
30
2.02
0.87
1.3
1.1
—
—
—
0
0
6
30
2.02
0.87
1.3
1.1
—
—
—
0
0
20
137
1.49
0.86
1.1
1.0
—
—
—
0
0
6
31
1.95
0.85
1.3
1.1
—
—
—
0
0
6
31
1.95
0.85
1.3
1.1
—
—
—
0
0
6
31
1.95
0.85
1.0
1.1
—
—
—
0
0
6
31
1.95
0.85
1.3
1.1
—
—
—
0
0
8
46
1.76
0.83
1.0
1.2
—
—
—
0
0
62
516
1.25
0.81
1.9
1.5
—
—
—
0
0
0
28
0.00
0.76
0.0
1.5
—
—
—
0
0
9
54
1.69
0.75
1.2
1.4
—
—
—
0
0
5
25
2.02
0.73
1.8
1.5
2.38
2.69
mg/l
—
5
25
21
284
0.72
0.71
1.9
1.8
—
—
—
0
0
5
28
1.80
0.66
1.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
2.0
—
—
—
0
0
8
54
1.49
0.57
2.1
1.5
—
—
—
0
0
6
36
1.68
0.57
3.0
2.3
—
—
—
0
0
10
65
1.56
0.56
1.4
1.7
—
—
—
0
0
52
447
1.20
0.52
2.5
2.7
0.52
0.70
ug/l
1.79
32
275
10
67
1.51
0.50
1.5
1.7
—
—
—
0
0
7
48
1.47
0.47
1.6
1.6
—
—
—
0
0
7
48
1.47
0.47
1.6
1.6
—
—
—
0
0
26
314
0.81
0.42
1.6
2.1
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
5
34
1.48
0.40
1.6
1.6
—
—
—
0
0
5
34
1.48
0.40
1.6
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
3.5
—
—
—
0
0
5
36
1.40
0.38
1.4
1.6
—
—
—
0
0
8
115
0.69
0.37
1.5
1.8
—
—
—
0
0
5
78
0.64
0.36
1.6
1.5
—
—
—
0
0
6
45
1.34
0.34
1.2
1.7
—
—
—
0
0
66
602
1.12
0.32
3.6
3.8
19.20
22.12
%
0.58
24
253
7
100
0.69
0.31
1.9
1.6
—
—
—
0
0
11
140
0.78
0.28
1.5
1.9
—
—
—
0
0
33
294
1.14
0.24
10.1
6.1
—
—
—
0
0
25
285
0.87
0.24
1.5
2.0
—
—
—
0
0
5
38
1.32
0.23
2.4
2.1
13.80
13.18
%
—
5
38
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
109.14
—
0
7
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
5
43
1.17
0.21
1.4
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
20
174
1.16
0.20
3.6
3.8
1.23
1.22
mmol/l
0.01
20
156
25
224
1.13
0.17
4.0
3.2
—
—
—
0
0
5
44
1.14
0.10
3.0
3.5
59.20
57.89
%
—
5
44
5
48
1.04
0.09
1.4
1.8
—
—
—
0
0
7
66
1.06
0.08
1.1
1.2
—
—
—
0
0
8
92
0.87
0.07
1.4
1.4
—
—
—
0
0
42
423
0.99
0.00
1.4
1.5
—
—
—
0
0
5
53
0.94
0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
27.00
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
9
92
0.98
-0.00
1.3
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
65.20
—
0
5
0
5
0.00
-0.00
0.0
3.4
—
57.54
—
0
5
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint NASH and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have NASH.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: NASH – Nonalcoholic steatohepatitis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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