Acute appendicitis, with complications

APPENDACUT_COMPLIC

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K35.0, K35.1
  • Hospital discharge: ICD-9 540[0-1]
  • Hospital discharge: ICD-8 540
  • Hospital discharge: excluded ICD-8 54090|54099
  • Cause of death: ICD-10 K35.0, K35.1
  • Cause of death: ICD-9 540[0-1]
  • Cause of death: ICD-8 540
  • Cause of death: excluded ICD-8 54090|54099

2 out of 7 registries used, show all original rules.

9323

4. Check minimum number of events

None

9323

5. Include endpoints

None

9323

6. Filter based on genotype QC (FinnGen only)

9074

Control definitions (FinnGen only)

Control exclude
K11_APPENDIX

Extra metadata

First used in FinnGen datafreeze
DF3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 84045 36878 46560
Only index persons 72602 32822 39780
Unadjusted period prevalence (%)
Whole population 1.19 1.06 1.30
Only index persons 1.38 1.21 1.52
Median age at first event (years)
Whole population 33.29 33.34 32.99
Only index persons 30.31 30.74 29.95

-FinnGen-

Key figures

All Female Male
Number of individuals 9074 4393 4681
Unadjusted period prevalence (%) 1.86 1.56 2.14
Median age at first event (years) 34.13 31.44 36.65

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
9323
Matched controls
93227
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
6421
FHL
Appendicectomy
20.4
307.7
1329
753
54091
ICD-8 Finland
Acute appendicitis, Gangraenosa, peritonitide non indicata
+∞
307.7
2019
*
K35.1
ICD-10 Finland
Acute appendicitis with peritoneal abscess
16384.0
307.7
1899
*
5400A
ICD-9 Finland
Acute appendicitis, With generalised peritonitis[APPENDICITIS ACUTA CUM PERITONITIDE DIFFUSA]
+∞
307.7
330
*
54001
ICD-8 Finland
Acute appendicitis, Cum peritonitide diffusa
+∞
307.7
463
*
JEA01
NOMESCO Finland
Laparoscopic appendectomy
94.8
307.7
1592
202
54003
ICD-8 Finland
Acute appendicitis, Cum abscessu
+∞
307.7
439
*
5400B
ICD-9 Finland
Acute appendicitis, With generalised peritonitis[APPENDICITIS ACUTA CUM PERITONITIDE CIRCUMSCRIPTA]
+∞
307.7
515
*
54002
ICD-8 Finland
Acute appendicitis, Cum peritonitide circumscripta
+∞
307.7
352
*
54000
ICD-8 Finland
Acute appendicitis, Perforans
+∞
307.7
656
*
K35.0
ICD-10 Finland
Acute appendicitis with generalized peritonitis
+∞
307.7
2307
*
5401A
ICD-9 Finland
Acute appendicitis, With peritoneal abscess
+∞
307.7
458
*
K35.9
ICD-10 Finland
Acute appendicitis, unspecified
586.5
307.7
1761
37
JEA00
NOMESCO Finland
Appendectomy
26.7
307.7
1883
874
ZXD05
NOMESCO Finland
Urgent procedure
2.2
266.6
3202
17750
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.9
230.0
1211
4545
P01AB01
ATC
metronidazole; oral, rectal
2.0
223.6
3995
25316
K37
ICD-10 Finland
Unspecified appendicitis
35.8
203.0
127
36
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
126.0
3260
22129
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
87.4
2294
15329
K36
ICD-10 Finland
Other appendicitis
436.8
87.2
87
*
K35
ICD-10 Finland
Acute appendicitis
20.1
86.2
66
33
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
79.6
1036
5619
JFB20
NOMESCO Finland
Ileocaecal resection
7.9
78.1
107
137
54099
ICD-8 Finland
Acute appendicitis, Without mention of peritonitis
+∞
74.0
71
*
D88
ICPC
Appendicitis
119.2
65.9
71
6
R10.0
ICD-10 Finland
Acute abdomen
2.9
65.8
323
1149
99850
ICD-8 Finland
Other complications of surgical procedures, Postoperative wound infection
7.2
62.5
92
128
5409X
ICD-9 Finland
Acute appendicitis, Without mention of peritonitis
+∞
61.5
59
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
58.9
1777
12119
JAH01
NOMESCO Finland
Laparoscopy
2.3
49.5
387
1723
C18.11
ICD-10 Finland
Malignant tumor of the appendix invasive carcinoma
9.9
44.5
51
52
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
42.7
1058
6842
JAH00
NOMESCO Finland
Laparotomy
2.6
42.4
253
996
C18.19
ICD-10 Finland
Malignant tumor in appendix other or unspecified histology
11.5
37.8
39
34
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.1
36.1
363
1786
J01DB01
ATC
cefalexin; oral
1.4
35.8
7129
65470
54009, ,
ICD-8 Finland
+∞
30.2
29
*
J01MA12
ATC
levofloxacin; systemic
1.4
29.7
1422
10492
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
29.1
2764
22671
ZXK00
NOMESCO Finland
Conversion from percutaneous endoscopic to open procedure
3.8
27.1
81
213
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.5
25.0
800
5454
JFB30
NOMESCO Finland
Right hemicolectomy
2.8
24.5
120
428
ZXE00
NOMESCO Finland
One hour or less
1.3
23.4
2919
24639
54200
ICD-8 Finland
Other appendicitis, Appendicitis chronica
+∞
22.9
22
*
UJF32
NOMESCO Finland
Coloscopy
1.3
22.0
1908
15355
54208
ICD-8 Finland
Other appendicitis
+∞
20.8
20
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.8
20.3
310
1757
JEA10
NOMESCO Finland
Appendectomy with drainage
57.6
19.9
23
*
54199
ICD-8 Finland
Appendicitis, unqualified
+∞
18.8
18
*
K65.0
ICD-10 Finland
Acute peritonitis
2.7
18.4
98
367
J01MA02
ATC
ciprofloxacin; systemic
1.2
18.2
2973
25685
D37.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Appendix
5.8
17.9
32
55
N02BE01
ATC
paracetamol; systemic, rectal
1.3
17.7
7539
71662
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
17.4
1578
12725
JN2AE
NOMESCO Finland
Ultrasound examination of lower part of abdomen without contrast
2.7
16.5
90
341
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
1.8
16.0
218
1195
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
2.2
15.5
126
573
WX402
NOMESCO Finland
General anaesthesia
1.3
15.3
1506
12256
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.5
14.1
471
3236
J01DA01
ATC
[U] cefalexin
1.2
13.8
4904
45141
JFK10
NOMESCO Finland
Freeing of adhesions in intestinal obstruction
4.2
13.6
35
83
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
2.2
13.5
113
522
JAK00
NOMESCO Finland
Laparotomy and drainage of peritoneal cavity
5.8
12.7
23
40
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
12.3
3373
30288
K56.7
ICD-10 Finland
Ileus, unspecified
2.1
12.1
118
578
B01AB05
ATC
enoxaparin; parenteral
1.2
11.8
2208
19164
C18.1
ICD-10 Finland
Malignant neoplasm: Appendix
10.0
11.5
22
22
JAD11
NOMESCO Finland
Laparoscopic repair of incisional hernia
2.3
11.3
81
351
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
2.3
11.3
79
339
JAD10
NOMESCO Finland
Repair of incisional hernia
2.7
10.6
55
205
C18.10
ICD-10 Finland
Malignant tumor of the appendix without histology
5.3
10.6
21
40
5420A
ICD-9 Finland
Other appendicitis[APPENDICITIS CHRONICA]
+∞
10.4
10
*
N70.0
ICD-10 Finland
Acute salpingitis and oophoritis
3.0
10.3
45
153
JAK03
NOMESCO Finland
Laparotomy and peritoneal irrigation
4.9
10.2
22
45
D01
ICPC
Abdominal pain/cramps general
1.3
10.2
698
5406
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
3.3
10.1
36
108
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.2
10.0
1186
9825
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
1.9
10.0
114
593
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
2.2
10.0
80
365
56096
ICD-8 Finland
Intestinal obstruction without mention of hernia, Ileus propter adhaesionem (functione laesa circulationis intestinalis non indicata)
4.6
9.5
22
48
K56.0
ICD-10 Finland
Paralytic ileus
2.4
9.5
64
271
WX704
NOMESCO Finland
Intubation
1.4
9.4
522
3922
C18.09
ICD-10 Finland
Malignant tumor of caecum other or unspecified histology
4.1
9.4
25
61
54308
ICD-8 Finland
Other diseases of appendix, Alii definiti
+∞
9.4
9
*
5428X
ICD-9 Finland
Other appendicitis[APPENDICITIS ALIA DEFINITA]
+∞
9.4
9
*
5410X
ICD-9 Finland
Appendicitis, unqualified[APPENDICITIS NUD]
+∞
9.4
9
*
D12.1
ICD-10 Finland
Benign neoplasm: Appendix
3.7
9.1
28
76
Z3226
NOMESCO Finland
Physiotherapist
1.2
9.1
1206
10102
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.2
8.7
1160
9723
JEW96
NOMESCO Finland
Other operation on appendix
50.0
8.7
10
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.1
8.6
5611
53109
I50
ICD-10 Finland
Heart failure
1.7
8.6
163
988
C18.01
ICD-10 Finland
Malignant tumor of the caecum invasive carcinoma
2.4
8.4
56
236
54090
ICD-8 Finland
Acute appendicitis, Phlegmonosa, peritonitide non indicata
+∞
8.3
8
*
A41.9
ICD-10 Finland
Sepsis, unspecified
1.5
8.2
214
1400
JAL20
NOMESCO Finland
Excision or destruction of lesion of peritoneum
3.0
8.2
34
112
56709
ICD-8 Finland
Peritonitis, Unspecified
33.4
8.1
10
*
6101
FHL
Exploratory laparotomy, includes possible biopases
3.2
8.0
30
93
6429
FHL
Other measure in this category
22.0
8.0
11
5
8240/3-C18.1
ICD-O-3
Neuroendocrine tumor, NOS, of appendix
10.8
7.8
14
13
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
1.8
7.7
109
611
8140/3-C18.1
ICD-O-3
Adenocarcinoma, NOS, of appendix
18.4
7.6
11
6
K50.0
ICD-10 Finland
Crohn disease of small intestine
1.8
7.6
97
527
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
2.6
7.5
40
152
JFB00
NOMESCO Finland
Partial resection of small intestine
1.9
7.5
96
521
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.2
7.5
1315
11304
K38.8
ICD-10 Finland
Other specified diseases of appendix
80.2
7.4
8
*
JFB33
NOMESCO Finland
Other resection comprising small intestine and colon
3.9
7.4
21
54
M01AE03
ATC
ketoprofen; systemic, rectal
1.1
7.4
2632
23887
6561
FHL
Removal of fasteners and related measures
4.0
7.3
20
50
J01FF01
ATC
clindamycin; systemic
1.2
7.3
1894
16801
9985A
ICD-9 Finland
Other complications of procedures, not elsewhere classified, Postoperative infection
2.4
7.3
46
190
54093, ,
ICD-8 Finland
+∞
7.3
7
*
8240/3-C18.2
ICD-O-3
Neuroendocrine tumor, NOS, of ascending colon
9.3
7.3
14
15
N05AH02
ATC
clozapine; systemic
1.7
7.2
114
659
5608A
ICD-9 Finland
Intestinal obstruction without mention of hernia, Other specified intestinal obstruction[OBSTRUCTIO INTESTINALIS ,ADHESIONES INTRAABDOMINALE]
3.4
7.2
25
74
E9499
ICD-8 Finland
Late effect of other surgical and medical procedures
4.2
7.0
18
43
D06
ICPC
Abdominal pain localized other
1.3
6.9
498
3888
55121
ICD-8 Finland
Other hernia of abdominal cavity without mention of obstruction, Alia hernia ventralis (incisionalis, in cicactrice)
3.7
6.9
21
57
61602
ICD-8 Finland
Diseases of parametrium and pelvic peritoneum (female), Abscessus fossae Douglasi
13.8
6.9
11
8
6565
FHL
Sewerage the other way
40.0
6.8
8
*
K45
ICD-10 Finland
Other abdominal hernia
3.6
6.7
21
58
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.2
6.7
1083
9238
SPAT1153
SPAT
Removal of sutures
1.1
6.7
2125
19113
XX4AT
NOMESCO Finland
Other canalization with ultrasound guidance
2.6
6.6
35
133
JAK04
NOMESCO Finland
Laparoscopy and peritoneal irrigation
7.8
6.6
14
18
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
2.3
6.4
43
184
5609X
ICD-9 Finland
Intestinal obstruction without mention of hernia, Unspecified intestinal obstruction
3.7
6.3
19
51
M01AE01
ATC
ibuprofen; systemic, rectal
1.2
6.3
7633
74277
C18.12
ICD-10 Finland
Malignant tumor of the appendix carcinoma of the adenoma
11.0
6.3
11
10
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
1.8
6.3
93
530
K35.2
ICD-10 Finland
Acute appendicitis with generalized peritonitis
+∞
6.2
6
*
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
2.0
6.2
61
304
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.3
6.2
373
2846
R4110
NOMESCO Finland
Physiotherapy
1.1
6.2
1877
16823
F20.9
ICD-10 Finland
Schizophrenia, unspecified
1.6
6.1
126
784
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.2
6.0
1039
8917

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1558
9256
1.82
91.01
1.3
1.3
—
—
—
0
0
2613
19785
1.45
51.12
4.5
4.4
—
—
—
0
0
1540
10563
1.55
48.75
1.9
2.1
—
—
—
0
0
2919
23235
1.37
40.67
2.5
2.4
—
—
—
0
0
2840
23135
1.33
32.14
2.7
2.6
57.08
60.12
u/l
1.01
2631
21442
4418
38453
1.28
29.64
6.2
6.4
11.61
11.53
umol/l
0.16
4212
36550
2173
17745
1.29
22.52
2.5
2.4
—
—
—
0
0
3956
34742
1.24
21.96
2.7
2.6
—
—
—
0
0
1192
9176
1.34
18.53
8.3
7.5
104.51
104.51
mmol/l
0.00
1192
9168
3863
34258
1.22
18.33
14.2
14.6
1.23
1.26
inr
1.57
1130
9976
4763
43522
1.19
15.31
5.3
4.8
6.78
6.72
mmol/l
1.13
4491
40818
5134
47512
1.18
13.36
4.3
4.2
276.25
1484.99
e6/l
3.75
97
658
4687
43080
1.18
13.16
10.1
9.3
4.41
4.07
e9/l
14.99
4091
37662
899
6992
1.32
12.81
2.6
2.6
33.91
47.56
u/l
1.13
782
6006
3115
27742
1.18
12.62
3.6
3.5
41.70
76.10
ng/l
1.14
2121
18663
6090
57394
1.18
11.95
8.0
7.7
77.91
78.07
u/l
0.09
5786
54293
1802
15384
1.21
11.45
2.7
2.6
6.92
5.13
e6/l
3.09
1618
13834
2516
22192
1.18
11.10
3.4
3.2
78.94
87.12
e6/l
0.08
1973
17075
2191
19144
1.19
10.72
4.3
4.0
89.35
90.04
%
0.64
2142
18662
693
5370
1.31
10.12
3.1
3.4
4.71
4.65
kpa
0.23
665
5192
833
6635
1.28
9.86
3.8
4.1
5.82
5.83
kpa
0.12
801
6439
802
6422
1.27
9.10
8.7
7.5
1.33
1.36
mmol/l
0.37
783
6246
823
6619
1.27
9.00
3.8
4.1
1.66
1.93
mmol/l
1.20
695
5596
3473
31804
1.15
8.89
5.2
5.0
35.03
35.59
g/l
6.76
3220
29662
851
6901
1.26
8.68
3.8
4.1
7.38
7.37
ph
0.13
13
57
762
6118
1.27
8.46
10.2
9.0
—
—
—
0
0
3537
32550
1.14
8.22
7.0
6.2
1.21
1.21
mmol/l
0.23
3253
29841
2271
20265
1.16
8.22
3.3
3.2
0.54
0.43
e6/l
0.59
1765
15408
2211
19735
1.16
7.93
3.2
3.1
—
—
—
0
0
1665
14575
1.17
7.66
3.0
2.9
542.47
548.82
mosm/kgh2o
0.52
1429
12557
1133
9609
1.20
7.50
6.4
6.2
1.03
1.04
mmol/l
0.58
1054
8988
5336
50597
1.13
7.34
4.3
4.1
—
—
—
0
0
2827
25797
1.14
7.25
3.9
3.7
74.70
86.49
e6/l
0.47
2098
18386
1029
8715
1.20
6.90
2.7
2.8
9.07
8.67
umol/l
0.18
892
7616
5440
51738
1.12
6.88
3.2
3.1
49.72
49.29
u/l
0.14
5131
48519
582
4643
1.27
6.84
11.3
9.6
0.68
0.67
%
0.12
577
4609
582
4657
1.27
6.68
11.3
9.4
1.37
1.38
%
0.10
577
4626
7737
75383
1.15
6.21
16.0
14.1
32.93
23.52
mg/l
60.41
6422
59740
885
7492
1.20
5.96
4.3
4.1
17.81
28.72
ug/l
0.84
715
6092
574
4649
1.25
5.96
4.1
3.5
5.15
5.14
kpa
0.13
545
4398
896
7611
1.20
5.82
9.0
8.0
95.63
95.66
%
0.05
869
7339
3841
36037
1.11
5.78
7.8
6.9
1.21
1.21
mmol/l
0.52
3268
30706
3139
29150
1.12
5.69
3.3
3.2
5.77
5.82
ph
0.46
242
2404
563
4583
1.24
5.61
4.1
3.5
7.41
7.42
ph
0.25
85
579
7899
77206
1.15
5.52
17.9
15.9
139.59
139.69
mmol/l
3.66
7744
75362
828
7030
1.20
5.41
9.5
8.4
122.23
122.09
g/l
0.07
810
6847
3765
35373
1.11
5.41
6.8
6.5
8.54
8.62
%
0.78
3555
33183
3250
30331
1.11
5.27
2.1
2.1
—
—
—
0
0
7921
77493
1.15
5.22
18.1
16.0
3.97
3.97
mmol/l
1.67
7749
75496
2066
18820
1.13
5.16
7.4
7.0
—
—
—
0
0
3744
35242
1.10
5.08
6.8
6.5
—
—
—
0
0
3737
35197
1.10
4.98
6.5
6.2
2.83
2.87
%
0.53
3525
32957
3621
34068
1.10
4.91
6.6
6.2
0.67
0.68
%
0.90
3408
31817
150
1027
1.47
4.83
1.4
1.3
—
—
—
0
0
430
3459
1.25
4.80
4.2
4.4
24.08
24.14
mmol/l
0.15
415
3386
526
4342
1.22
4.64
3.1
3.6
129.78
129.72
g/l
0.02
512
4244
407
3268
1.26
4.63
2.6
3.0
0.64
0.65
%
0.14
407
3252
416
3351
1.25
4.61
2.6
3.1
1.33
1.29
%
0.23
416
3331
789
6781
1.18
4.51
8.1
7.8
10.14
9.82
mmol/l
0.61
754
6484
3843
36372
1.10
4.48
3.6
3.5
0.00
0.00
estimate
2.35
710
6401
3784
35833
1.09
4.30
6.3
6.0
57.78
57.24
%
1.96
3568
33653
1387
12470
1.13
4.25
2.9
2.8
1.12
1.11
e6/l
0.03
760
7134
3800
36013
1.09
4.22
4.8
4.7
0.00
0.00
estimate
1.34
734
6658
3836
36383
1.09
4.17
6.5
6.2
27.37
27.84
%
1.81
3624
34200
969
8519
1.15
4.15
8.7
7.5
12.16
12.46
kpa
1.03
931
8142
3800
36035
1.09
4.14
3.6
3.5
0.00
0.00
estimate
0.03
753
7011
969
8523
1.15
4.12
8.7
7.5
5.11
5.08
kpa
0.50
933
8140
221
1669
1.33
4.07
4.0
4.2
2.81
2.51
mmol/l
0.93
148
1122
221
1670
1.33
4.06
4.4
3.7
—
—
—
0
0
3957
37615
1.09
4.05
6.2
6.0
0.04
0.04
e9/l
0.50
3419
32624
965
8498
1.15
4.04
8.7
7.5
1.01
1.01
mmol/l
0.01
777
6705
1008
8905
1.15
4.03
1.8
1.8
—
—
—
0
0
1294
11623
1.13
4.02
3.1
3.0
3.00
2.27
e6/l
1.60
670
6338
2140
19795
1.11
3.93
3.3
3.1
—
—
—
0
0
404
3308
1.23
3.91
4.3
3.6
—
—
—
0
0
2176
20149
1.10
3.91
3.1
3.0
1320.29
1405.43
ng/l
0.53
1868
17262
398
3254
1.23
3.91
1.6
1.6
14.66
13.76
u/ml
0.04
12
93
3942
37521
1.09
3.85
6.2
6.0
0.60
0.59
e9/l
0.93
3420
32577
4077
38868
1.09
3.83
6.6
6.2
0.19
0.20
e9/l
0.88
3582
34233
1794
16466
1.11
3.82
1.8
1.8
1.44
1.17
mg/l
1.71
1376
12686
1346
12162
1.12
3.79
3.4
3.5
0.82
0.82
mmol/l
0.56
1264
11442
268
2105
1.28
3.74
2.0
2.2
7259.29
4910.59
u/l
0.35
100
833
123
861
1.43
3.64
2.9
3.2
3.00
12.96
nmol/l
0.91
117
837
2249
20958
1.10
3.50
4.0
3.8
—
—
—
0
0
350
2861
1.23
3.48
4.4
3.7
24.87
24.80
mmol/l
0.16
321
2614
5705
55262
1.08
3.47
4.1
4.0
12.31
11.77
mm/h
1.94
5278
51403
4042
38641
1.08
3.41
6.3
6.0
1.89
1.92
e9/l
0.61
3579
34294
410
3414
1.21
3.41
3.5
3.6
25.05
25.17
mmol/l
0.26
394
3303
27
126
2.15
3.40
1.2
1.3
—
—
—
0
0
3447
32790
1.08
3.26
10.8
9.6
0.00
0.00
e9/l
0.67
2805
26806
246
1950
1.27
3.24
3.9
4.2
7.42
7.42
ph
0.39
226
1768
326
2674
1.23
3.17
3.7
3.5
2629.17
2208.69
u/ml
0.06
283
2310
60
372
1.62
3.16
1.2
1.3
248.13
434.73
u/l
1.46
55
342
116
827
1.41
3.15
2.6
2.5
1.29
1.36
g/24h
0.10
61
429
128
929
1.38
3.14
1.8
1.9
90.22
89.56
%
0.68
128
914
18
73
2.47
3.12
7.1
9.6
—
—
—
0
0
342
2827
1.22
3.10
1.1
1.1
1.00
15.87
u/ml
—
9
41
170
1293
1.32
3.08
1.8
1.9
5.16
5.13
mmol/24h
0.03
157
1141
464
3960
1.18
2.98
12.6
9.8
24.36
24.24
mmol/l
0.32
449
3842
1441
13243
1.10
2.97
1.8
1.7
1186.52
1160.22
nmol/l
0.47
1103
10087
35
190
1.85
2.95
1.4
1.8
—
—
—
0
0
1116
10123
1.12
2.95
2.8
2.6
22.12
23.20
%
1.95
971
8692
2385
22440
1.08
2.92
2.1
2.2
272.96
218.00
u/l
0.62
2258
21082
2050
19170
1.09
2.90
4.0
3.9
0.00
0.00
estimate
2.77
670
6378
1275
11661
1.11
2.89
2.7
2.6
12.75
13.29
umol/l
1.95
1201
10917
1266
11577
1.11
2.88
2.2
2.1
29.92
29.87
s
0.10
1230
11231
476
4089
1.17
2.84
11.8
10.3
—
—
—
0
0
269
2191
1.23
2.84
2.7
2.7
3.77
3.60
g/l
1.03
253
2082
228
1823
1.26
2.84
2.4
2.3
113.00
116.77
ug/min
0.04
140
1117
352
2948
1.20
2.82
2.4
1.9
2.27
2.31
ug/l
0.02
320
2603
787
7015
1.13
2.81
2.3
2.3
0.21
0.21
g/l
0.36
725
6531
253
2056
1.24
2.74
1.5
1.4
5.64
13.76
iu/ml
—
9
44
338
2830
1.20
2.72
2.1
2.1
21.66
21.45
s
0.17
304
2466
198
1570
1.27
2.67
2.7
3.7
—
—
—
0
0
193
1527
1.27
2.65
3.7
3.5
446.66
573.73
u/ml
0.20
180
1397
2666
25278
1.08
2.64
3.2
3.3
31.88
34.88
u/l
1.37
2533
23994
311
2593
1.21
2.63
4.0
4.0
1.32
1.39
mmol/l
0.65
303
2551
95
679
1.40
2.61
1.5
1.4
150987.81
110946.45
e6/l
0.22
62
463
16
68
2.36
2.55
2.2
2.4
—
—
—
0
0
146
1126
1.30
2.47
6.2
5.1
360.98
366.09
umol/l
0.16
126
967
1179
10830
1.10
2.47
2.7
2.6
2.36
2.32
g/l
1.58
1107
10068
973
8859
1.11
2.43
1.4
1.5
—
—
—
0
0
3119
29817
1.07
2.41
2.3
2.2
76.46
76.51
nmol/l
0.04
2818
27040
298
2500
1.20
2.39
3.4
3.2
0.29
0.32
g/l
0.24
141
1120
119
900
1.33
2.33
1.1
1.3
—
—
—
0
0
1676
15679
1.08
2.33
4.1
3.9
1.02
1.02
kg/l
0.70
262
2346
194
1563
1.25
2.33
3.3
2.5
16.39
16.36
%
0.03
107
824
2547
24211
1.07
2.31
3.4
3.5
2.35
2.35
mmol/l
0.04
2234
21448
973
8885
1.11
2.31
2.3
2.4
117.10
133.15
ug/g
1.01
785
7133
926
8436
1.11
2.30
1.4
1.4
—
—
—
0
0
6629
64985
1.07
2.28
18.6
16.7
15.65
14.94
%
0.60
6516
63852
10
34
2.94
2.27
1.2
1.0
—
—
—
0
0
783
7075
1.12
2.27
4.5
4.4
—
—
—
0
0
285
2396
1.20
2.26
7.8
9.4
—
—
—
0
0
8160
80635
1.10
2.25
10.8
10.3
27.09
27.26
u/l
0.34
7920
77980
626
5585
1.13
2.25
1.2
1.2
—
—
—
0
0
594
5286
1.13
2.23
4.4
4.1
97.03
93.11
ng/l
0.37
520
4602
304
2576
1.19
2.21
1.6
1.6
123.75
292.98
titre
1.71
16
104
1672
15681
1.08
2.19
1.3
1.3
2.18
1.79
u/ml
0.42
452
4315
2149
20356
1.07
2.15
2.7
2.6
3060.40
4267.28
umol/l
0.88
1884
17999
1930
18220
1.07
2.12
2.3
2.2
2.96
2.93
mg/l
0.20
1669
15613
169
1358
1.25
2.11
3.5
2.8
—
—
—
0
0
448
3933
1.15
2.09
3.0
2.7
0.30
0.27
e6/l
0.19
434
3829
129
1005
1.29
2.08
1.1
1.3
0.61
1.95
nmol/l
0.61
118
971
967
8879
1.10
2.07
4.4
4.4
31.73
31.98
%
0.31
694
6251
2439
23231
1.07
2.07
3.4
3.2
7.81
7.83
mmol/l
0.10
2113
19666
2176
20647
1.07
2.07
2.9
3.0
—
—
—
0
0
2243
21309
1.07
2.05
4.6
4.2
7.40
7.40
ph
0.60
443
4089
2401
22866
1.07
2.04
4.0
3.8
9.75
9.16
mg/mmol
0.28
1593
14773
335
2895
1.16
1.96
4.9
4.8
—
—
—
0
0
127
999
1.27
1.93
2.5
2.8
—
—
—
0
0
15
71
2.11
1.91
2.6
2.4
0.27
0.46
u/field
0.71
15
71
71
514
1.38
1.90
1.2
1.1
—
—
—
0
0
887
8152
1.10
1.88
3.1
2.5
1.78
1.78
%
0.05
784
7215
101
1303
0.77
1.84
1.2
1.2
—
—
—
0
0
54
375
1.44
1.83
1.7
2.0
—
—
—
0
0
128
1018
1.26
1.80
1.1
1.3
0.23
0.25
nmol/l
—
6
65
548
4931
1.12
1.77
2.4
2.3
—
—
—
0
0
1731
16383
1.07
1.77
1.6
1.5
19.85
20.09
nmol/l
0.29
1495
14136
692
6308
1.10
1.75
2.2
2.3
6.98
7.70
ug/l
0.56
610
5536
15
74
2.03
1.74
1.6
2.1
—
—
—
0
0
2277
21752
1.06
1.74
3.4
3.3
450.20
416.40
mg/l
0.12
1517
14121
3051
29394
1.06
1.73
2.0
2.0
95.40
95.21
pmol/l
0.08
1672
15683
8489
84180
1.09
1.72
22.9
20.4
91.02
91.00
fl
0.18
8394
83063
37
241
1.54
1.72
5.3
3.5
57.15
53.35
%
0.51
37
230
8477
84057
1.09
1.72
23.2
20.6
40.19
40.82
%
4.09
8013
78965
150
1223
1.23
1.71
3.7
3.0
0.87
0.83
nmol/l
0.50
122
907
183
1523
1.21
1.70
3.1
3.2
1.62
1.62
mmol/l
0.02
176
1488
665
6061
1.10
1.70
2.9
2.5
69.93
69.88
e9/l
0.01
493
4581
17
89
1.91
1.69
1.6
1.3
18.84
26.36
%
0.36
11
67
8489
84193
1.09
1.68
23.0
20.5
4.50
4.52
e12/l
5.65
8262
81932
8482
84121
1.09
1.67
23.0
20.5
250.47
250.28
e9/l
0.10
8290
82086
295
2561
1.16
1.67
2.6
2.4
451.08
599.48
ug/l
0.64
276
2404
150
1227
1.23
1.66
3.2
3.4
1.80
1.62
%
0.23
136
1093
8490
84214
1.09
1.64
23.1
20.6
135.52
136.53
g/l
8.25
8389
83095
8486
84175
1.09
1.63
22.8
20.4
30.35
30.35
pg
0.02
8391
83061
373
3307
1.13
1.57
2.0
1.7
1.59
1.54
g/l
0.40
319
2829
7941
78588
1.07
1.57
14.5
13.1
—
—
—
0
0
112
894
1.26
1.57
1.1
1.3
—
—
nmol/l
—
0
0
8486
84196
1.09
1.55
23.0
20.5
6.84
6.70
e9/l
5.73
8256
81912
129
1048
1.23
1.55
2.1
2.1
—
—
—
0
0
49
347
1.41
1.54
1.1
1.1
168.65
180.74
iu/ml
0.18
49
347
24
146
1.65
1.50
1.1
1.1
—
—
—
0
0
101
803
1.26
1.48
9.8
14.0
7.19
7.41
mmol/l
0.32
77
674
32
210
1.53
1.48
1.0
1.1
—
—
—
0
0
255
2217
1.15
1.46
3.3
3.1
—
—
—
0
0
60
447
1.34
1.42
10.8
12.5
0.63
0.62
mmol/l
0.08
53
409
512
4656
1.11
1.41
7.0
7.0
24.53
24.47
mmol/l
0.16
493
4434
465
4212
1.11
1.39
1.2
1.2
—
—
—
0
0
12
60
2.00
1.37
1.1
1.3
143.83
111.12
ug/l
—
6
33
651
5999
1.09
1.37
2.6
2.5
66.32
66.58
g/l
0.36
589
5505
256
2240
1.15
1.36
3.6
3.2
45.22
81.98
mg/l
0.79
204
1814
86
679
1.27
1.36
1.5
1.5
32.05
29.69
%
0.26
54
407
87
688
1.27
1.35
1.5
1.4
6.74
6.32
mmol/l
0.53
79
640
64
486
1.32
1.35
1.5
1.6
1943.70
1960.90
ml
0.04
64
477
10
195
0.51
1.32
1.2
1.4
—
—
—
0
0
56
419
1.34
1.31
2.2
2.8
7.41
7.42
ph
0.34
12
149
74
577
1.28
1.30
1.2
1.4
—
—
—
0
0
255
2239
1.14
1.30
3.6
3.2
30.71
51.42
mg/l
2.49
204
1817
53
394
1.35
1.30
1.5
1.6
—
—
—
0
0
35
242
1.45
1.29
1.3
1.4
614.64
265.63
nmol/24h
0.28
35
242
296
2626
1.13
1.29
2.5
2.0
—
—
—
0
0
299
2655
1.13
1.29
2.6
2.1
—
—
—
0
0
241
2745
0.87
1.28
1.6
1.7
—
—
—
0
0
657
6080
1.09
1.27
4.1
3.8
—
—
—
0
0
23
146
1.58
1.25
3.6
2.0
6.93
7.74
mmol/l
0.68
12
84
55
414
1.33
1.25
3.7
3.5
30.18
27.34
mu/l
0.23
48
392
279
2472
1.13
1.25
2.7
2.1
—
—
—
0
0
51
380
1.34
1.24
2.0
1.7
2.00
3.09
u/field
0.71
37
270
105
860
1.22
1.23
1.6
1.8
—
—
—
0
0
7290
72095
1.05
1.22
3.9
3.9
1.35
1.31
mmol/l
4.41
6725
66663
1089
10288
1.07
1.22
1.4
1.3
604.93
512.76
titre
0.72
227
2098
105
863
1.22
1.19
2.1
2.4
—
—
—
0
0
300
2681
1.12
1.18
2.6
2.1
—
—
—
0
0
299
2673
1.12
1.18
2.6
2.0
—
—
—
0
0
14
79
1.77
1.16
1.5
1.4
124.71
168.06
mmol/l
1.18
14
73
89
722
1.23
1.15
1.1
1.2
—
—
—
0
0
247
2186
1.13
1.15
3.6
3.2
2.37
3.35
ratio
0.41
16
173
142
1207
1.18
1.14
1.7
1.4
—
—
—
0
0
42
310
1.36
1.11
1.9
1.6
—
—
—
0
0
45
336
1.34
1.11
1.1
1.3
174.16
169.51
mmol/24h
0.11
45
336
110
917
1.20
1.11
1.5
1.6
—
—
—
0
0
193
1686
1.15
1.10
2.9
2.2
129.80
130.10
g/l
0.06
146
1203
106
882
1.20
1.09
2.1
2.3
105.01
105.40
mmol/l
0.34
106
870
106
882
1.20
1.09
2.1
2.3
4.05
4.08
mmol/l
0.33
106
870
3257
31728
1.04
1.09
3.0
2.8
140.02
135.93
ug/l
0.36
3031
29531
1612
15463
1.05
1.07
1.7
1.7
25257410.37
31907788.44
pmol/l
0.23
1362
12997
166
1438
1.16
1.07
3.3
3.3
7.67
7.58
mmol/l
0.09
161
1409
119
1004
1.19
1.06
1.5
1.5
34.91
62.44
mu/l
3.00
108
895
33
453
0.73
1.04
3.0
2.8
32.06
40.71
%
1.21
16
252
109
915
1.19
1.03
1.7
1.6
57.30
58.32
%
0.10
69
570
334
3031
1.11
1.03
4.4
5.3
1.70
1.68
%
0.06
311
2845
1325
12661
1.05
1.03
1.8
1.8
—
—
—
0
0
11
60
1.83
1.02
1.1
1.2
—
—
—
0
0
525
4870
1.08
1.01
4.6
4.9
—
—
—
0
0
42
316
1.33
1.00
1.0
1.1
14.67
5.27
u/ml
—
8
50
230
2050
1.12
0.99
3.5
3.0
1.80
1.53
mg/l
3.99
214
1892
216
1918
1.13
0.99
1.3
1.3
2.81
7.04
u/ml
2.70
33
314
9
49
1.84
0.98
1.8
1.5
439.56
327.06
umol/24h
—
9
49
0
30
0.00
0.97
0.0
1.0
—
—
—
0
0
0
30
0.00
0.97
0.0
1.0
—
—
—
0
0
0
30
0.00
0.97
0.0
1.0
—
—
—
0
0
0
30
0.00
0.97
0.0
1.0
—
—
—
0
0
94
785
1.20
0.96
4.2
3.9
—
—
—
0
0
0
31
0.00
0.96
0.0
1.0
—
—
—
0
0
202
1793
1.13
0.95
1.8
1.6
13236.76
13042.72
e6/l
0.02
156
1280
156
1361
1.15
0.94
3.5
3.1
—
—
—
0
0
32
433
0.74
0.94
1.3
1.5
1.08
1.19
nmol/l
0.32
26
331
177
1559
1.14
0.94
3.9
3.5
31.41
26.51
mg/l
0.87
112
980
1459
14015
1.05
0.93
1.5
1.5
2.39
2.48
g/l
0.99
887
8810
178
1571
1.14
0.92
1.5
1.5
—
—
—
0
0
174
1535
1.14
0.91
2.9
1.9
0.76
0.84
nmol/l
0.94
139
1297
37
279
1.33
0.89
1.9
1.4
64.74
64.08
%
0.04
27
233
196
1745
1.13
0.89
3.5
2.9
—
—
—
0
0
75
619
1.21
0.88
1.1
1.2
—
—
—
0
0
44
341
1.29
0.88
2.9
3.0
—
—
—
0
0
36
271
1.33
0.88
5.3
5.1
—
—
—
0
0
10
169
0.59
0.88
1.5
1.4
—
—
—
0
0
211
1889
1.12
0.88
1.3
1.3
4.90
4.83
u/ml
0.01
24
191
40
517
0.77
0.87
1.0
1.0
—
—
—
0
0
241
2175
1.11
0.87
1.5
1.4
290.31
272.27
ug/g
0.67
142
1284
1485
14302
1.05
0.86
3.8
3.7
368.38
552.86
ng/l
1.15
1137
10989
109
934
1.17
0.86
1.3
1.4
280.49
422.25
pmol/l
0.70
96
797
244
2207
1.11
0.85
1.3
1.2
—
—
—
0
0
230
2074
1.11
0.85
1.3
1.3
32.64
37.60
u/ml
0.09
15
132
241
2179
1.11
0.85
1.9
1.7
0.23
0.24
g/l
0.15
225
2066
517
4837
1.07
0.84
1.2
1.2
128.96
146.20
iu/ml
0.49
208
1868
47
371
1.27
0.83
2.2
2.2
2471.95
2031.11
ml
0.85
41
329
16
238
0.67
0.82
1.2
1.2
—
26.20
%
—
0
30
40
512
0.78
0.82
1.1
1.0
704.71
731.44
ng/l
0.16
31
344
18
121
1.49
0.82
2.1
1.4
9.44
9.48
%
—
9
65
1739
16825
1.04
0.82
3.4
3.5
—
—
—
0
0
46
363
1.27
0.82
32.2
34.6
7.18
7.39
ug/l
0.31
40
335
11
65
1.69
0.82
1.5
1.0
20.33
14.67
iu/ml
—
6
24
223
2013
1.11
0.82
1.5
1.4
—
—
—
0
0
27
197
1.37
0.81
1.6
1.9
—
—
—
0
0
607
5717
1.07
0.81
2.8
2.6
10.30
10.59
g/l
1.04
541
5245
160
1418
1.13
0.80
1.6
1.5
109.08
115.12
u/ml
0.42
45
315
40
510
0.78
0.80
1.1
1.0
327.17
318.09
ng/l
0.09
30
355
625
5896
1.06
0.80
4.3
3.9
1.23
1.23
mmol/l
0.01
570
5180
173
1543
1.12
0.79
1.2
1.3
51.40
41.28
u/ml
0.25
19
152
64
772
0.83
0.78
2.8
2.7
—
—
—
0
0
614
5794
1.06
0.78
3.7
4.0
0.72
0.67
%
0.20
231
1919
29
216
1.34
0.78
1.3
1.2
42.13
39.33
g/l
0.44
12
118
44
348
1.27
0.78
1.2
1.6
7.71
12.37
nmol/l
0.22
35
282
167
1488
1.12
0.78
1.7
1.6
—
—
—
0
0
12
74
1.62
0.78
4.1
1.6
—
—
—
0
0
27
199
1.36
0.78
1.2
1.2
854.72
402.80
ug/l
0.26
18
108
0
27
0.00
0.77
0.0
4.3
—
3.67
—
0
18
131
1151
1.14
0.76
3.8
2.9
—
—
—
0
0
199
2204
0.90
0.76
1.1
1.1
—
—
—
0
0
264
2417
1.09
0.75
1.7
1.6
292.09
296.26
mu/l
0.10
242
2206
5
24
2.08
0.74
1.0
1.2
—
—
—
0
0
373
3468
1.08
0.74
1.0
1.1
—
—
—
0
0
189
1703
1.11
0.74
3.5
3.4
—
—
—
0
0
670
6354
1.06
0.74
4.0
4.2
0.91
0.94
%
0.09
264
2211
2129
20724
1.04
0.74
1.4
1.4
—
—
—
0
0
126
1110
1.14
0.72
2.2
2.4
—
—
—
0
0
39
308
1.27
0.71
1.4
1.7
2.43
1.95
umol/l
1.26
34
288
11
68
1.62
0.71
1.1
1.2
—
—
—
0
0
71
599
1.19
0.71
2.5
2.3
647.87
652.31
ml
0.03
47
407
214
1947
1.10
0.70
1.1
1.1
8.07
6.82
u/ml
0.15
30
265
5724
56596
1.03
0.70
4.0
3.9
14.74
14.71
pmol/l
0.34
5217
51810
38
300
1.27
0.70
2.4
2.4
—
—
—
0
0
238
2178
1.10
0.70
2.6
2.1
37.27
37.85
g/l
0.72
210
1929
15
217
0.69
0.70
1.9
2.0
—
—
—
0
0
28
212
1.32
0.70
1.1
1.5
—
—
—
0
0
9
58
1.55
0.69
1.0
1.1
—
—
—
0
0
33
421
0.78
0.69
1.0
1.0
0.68
0.94
u/ml
0.36
14
94
6979
69220
1.03
0.69
5.8
5.6
39.98
39.72
mmol/mol
1.43
6484
64476
246
2256
1.09
0.69
1.9
1.6
1.17
1.19
g/l
0.34
232
2141
1326
12811
1.04
0.69
1.3
1.3
23.58
33.08
iu/ml
2.86
403
4144
120
1058
1.14
0.69
2.7
2.7
149.73
1466.19
u/ml
0.84
120
1044
104
909
1.15
0.68
1.3
1.2
—
—
—
0
0
287
2653
1.08
0.68
2.4
2.3
2.97
2.93
g/l
0.27
259
2409
20
144
1.39
0.67
1.2
1.3
0.83
110.79
mg/l
1.26
14
110
15
102
1.47
0.67
1.1
1.0
—
—
—
0
0
67
566
1.19
0.67
1.2
1.2
—
—
—
0
0
5
91
0.55
0.67
2.0
1.1
—
—
—
0
0
7
43
1.63
0.66
1.0
1.1
—
36.00
—
0
15
5
28
1.79
0.66
7.4
7.8
—
—
—
0
0
321
2988
1.08
0.64
4.6
5.4
0.86
0.90
%
0.96
301
2807
224
2055
1.09
0.64
2.6
2.2
—
—
—
0
0
30
233
1.29
0.64
1.9
1.5
2.12
2.90
%
0.28
24
200
18
247
0.73
0.64
1.8
2.0
—
—
—
0
0
6461
65163
0.97
0.63
19.8
17.7
332.74
332.80
g/l
0.19
6419
64670
192
1752
1.10
0.62
1.8
1.8
3.78
9.34
iu/l
0.60
69
643
67
571
1.17
0.62
2.2
1.8
7.48
6.69
mmol/l
1.05
51
397
5
30
1.67
0.61
5.2
5.7
1.48
0.83
mg/l
—
5
22
70
600
1.17
0.61
2.0
2.5
10.83
11.11
%
0.21
70
600
44
361
1.22
0.61
1.3
1.5
3.71
3.52
%
—
7
88
31
244
1.27
0.61
1.3
1.1
—
—
—
0
0
238
2576
0.92
0.60
1.1
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.8
—
2258.40
—
0
5
111
985
1.13
0.60
1.7
1.5
33.05
32.95
g/l
0.03
103
891
0
21
0.00
0.60
0.0
1.5
—
4.53
—
0
21
42
510
0.82
0.60
1.4
1.3
1.52
1.56
g/l
0.44
42
510
65
555
1.17
0.59
1.9
1.9
3.03
1.74
u/field
0.91
35
227
137
1232
1.11
0.59
1.1
1.1
109.13
8394.92
iu/ml
0.54
23
284
631
6021
1.05
0.59
4.1
4.2
0.10
0.10
%
0.01
226
1879
233
2152
1.08
0.59
1.3
1.3
9.03
9.96
u/l
0.47
186
1762
116
1035
1.12
0.58
5.6
6.6
11.23
11.50
mg/l
0.28
109
956
79
687
1.15
0.58
1.2
1.1
—
—
—
0
0
84
734
1.15
0.58
3.7
3.4
—
—
—
0
0
1095
10586
1.04
0.58
1.6
1.6
—
—
—
0
0
891
8579
1.04
0.57
1.6
1.6
—
—
—
0
0
12
81
1.48
0.57
1.3
1.3
—
—
—
0
0
135
1218
1.11
0.56
1.1
1.3
61.75
36.44
u/l
0.48
119
1056
31
386
0.80
0.56
1.1
1.0
0.26
1.17
u/ml
—
9
99
32
397
0.81
0.56
1.5
1.4
—
—
—
0
0
62
532
1.17
0.55
2.8
2.5
—
—
—
0
0
41
339
1.21
0.54
3.0
3.2
—
—
—
0
0
125
1127
1.11
0.54
1.1
1.1
122.13
117.14
%
1.08
118
1019
21
272
0.77
0.53
1.1
1.2
—
—
—
0
0
6
39
1.54
0.53
1.0
1.1
—
—
—
0
0
157
1435
1.10
0.52
1.2
1.3
274.73
280.47
u/ml
0.08
102
913
19
143
1.33
0.52
1.5
2.0
19.14
17.52
umol/l
0.17
19
143
40
332
1.21
0.52
5.4
5.5
4954.61
763.25
mg/l
0.39
31
239
14
100
1.40
0.51
1.5
1.4
9.79
328402.79
nmol/l
0.72
14
81
9
64
1.41
0.51
1.2
1.3
—
18.71
—
0
21
232
2159
1.08
0.51
1.2
1.3
220.29
216.12
miu/ml
0.06
98
978
6888
68420
1.03
0.51
4.7
4.5
2.88
2.12
mu/l
0.74
6340
62971
62
714
0.87
0.50
1.4
1.4
1.24
1.38
promille
0.29
47
549
784
8132
0.96
0.50
1.4
1.4
—
—
—
0
0
85
753
1.13
0.50
1.9
1.5
—
—
—
0
0
1569
16078
0.97
0.50
2.9
2.9
0.77
0.76
ug/l
0.12
1019
10352
21
269
0.78
0.50
1.6
1.7
—
—
—
0
0
162
1488
1.09
0.49
1.5
1.4
—
—
—
0
0
28
346
0.81
0.49
1.1
1.1
1539.77
1533.97
miu/ml
0.01
28
346
52
446
1.17
0.48
1.3
1.4
5.18
6.24
u/l
1.10
39
387
66
752
0.88
0.47
1.2
1.2
—
—
—
0
0
596
5721
1.04
0.47
4.1
4.2
0.82
0.30
%
0.48
190
1593
169
1561
1.08
0.46
1.2
1.2
20.17
25.13
u/ml
—
6
19
20
155
1.29
0.46
1.1
1.5
—
—
—
0
0
49
420
1.17
0.46
2.3
2.2
490.36
493.08
min
0.06
36
319
89
993
0.90
0.46
1.1
1.1
5.06
3.23
u/ml
0.43
40
450
59
676
0.87
0.46
1.4
1.3
164.25
182.09
pmol/l
0.43
59
676
483
4618
1.05
0.46
1.4
1.3
249.18
236.40
u/ml
0.08
453
4276
37
440
0.84
0.46
1.1
1.1
3.37
10.75
nmol/l
—
8
87
34
282
1.21
0.46
1.1
1.1
—
—
—
0
0
17
129
1.32
0.45
1.5
1.1
—
—
—
0
0
17
129
1.32
0.45
1.5
1.1
—
—
—
0
0
17
129
1.32
0.45
1.5
1.1
—
—
—
0
0
8
119
0.67
0.45
1.3
1.6
—
—
—
0
0
181
1679
1.08
0.45
1.6
1.6
—
—
—
0
0
257
2416
1.07
0.45
1.7
1.7
—
—
—
0
0
498
4769
1.05
0.45
3.1
2.8
—
—
—
0
0
7
51
1.37
0.44
2.0
1.5
0.21
0.81
%
—
7
33
74
831
0.89
0.44
1.0
1.1
2.69
0.35
u/ml
0.49
20
223
686
7107
0.96
0.43
1.4
1.4
—
—
—
0
0
7670
76341
1.03
0.43
4.8
4.8
2.76
2.79
mmol/l
1.30
7128
71014
82
734
1.12
0.43
2.2
2.4
1.10
1.18
e9/l
0.30
73
654
232
2178
1.07
0.43
1.2
1.2
1186.67
796.09
titre
—
6
69
683
6594
1.04
0.43
1.4
1.4
—
—
—
0
0
581
5592
1.04
0.42
1.4
1.4
—
—
—
0
0
20
158
1.27
0.41
6.8
5.9
—
—
—
0
0
472
4920
0.96
0.41
1.4
1.4
—
—
—
0
0
88
794
1.11
0.41
1.2
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
97
1067
0.91
0.41
1.1
1.3
7.83
7.27
mmol/l
0.87
85
953
114
1244
0.92
0.40
1.9
1.6
—
—
—
0
0
69
615
1.12
0.40
1.1
1.0
275.57
282.85
mg/l
0.40
58
559
20
159
1.26
0.40
3.4
2.9
—
—
—
0
0
11
149
0.74
0.40
1.2
1.1
0.54
0.70
umol/24h
—
5
74
158
1698
0.93
0.39
6.7
7.2
105.62
105.19
mmol/l
0.56
146
1530
51
446
1.14
0.39
1.6
1.6
—
—
—
0
0
158
1697
0.93
0.39
6.7
7.2
11.10
11.31
mmol/l
0.42
146
1529
47
409
1.15
0.39
1.5
1.3
—
—
—
0
0
617
5960
1.04
0.39
3.7
3.4
—
—
—
0
0
33
279
1.18
0.38
1.1
1.2
—
—
—
0
0
222
2092
1.06
0.38
1.1
1.2
—
—
—
0
0
115
1249
0.92
0.38
1.1
1.1
—
—
—
0
0
26
215
1.21
0.38
1.3
1.1
—
—
—
0
0
49
558
0.88
0.38
1.5
1.6
83.00
82.77
umol/l
0.02
49
558
298
2835
1.05
0.37
2.4
2.2
7.44
7.35
g/l
0.37
269
2588
9
68
1.32
0.37
1.0
1.1
—
—
—
0
0
15
116
1.29
0.37
3.1
3.2
—
—
—
0
0
38
327
1.16
0.37
3.7
2.5
—
—
—
0
0
84
924
0.91
0.36
1.1
1.1
3.02
3.53
u/ml
0.12
35
356
10
72
1.39
0.36
2.3
2.5
179.90
196.83
umol/l
—
10
66
72
649
1.11
0.36
1.2
1.2
400.35
360.59
nmol/l
0.81
60
552
79
716
1.10
0.36
1.2
1.2
—
—
—
0
0
91
831
1.10
0.35
2.3
2.4
—
—
—
0
0
5
76
0.66
0.35
1.2
1.2
1.40
1.72
umol/24h
—
5
76
13
99
1.31
0.35
2.6
3.6
47.00
40.03
umol/l
0.57
13
80
16
126
1.27
0.35
1.7
1.7
151.67
150.02
ng/l
0.01
16
126
59
527
1.12
0.35
2.3
2.6
522.45
488.83
e6/l
0.15
49
441
103
1118
0.92
0.34
1.1
1.1
2.44
13.30
au/ml
—
7
62
277
2638
1.05
0.34
2.4
2.2
9.87
10.24
g/l
0.96
244
2376
6
44
1.36
0.34
5.0
2.7
—
—
—
0
0
20
163
1.23
0.34
1.6
1.9
—
—
—
0
0
1242
12164
1.02
0.33
1.3
1.3
10.15
12.27
u/ml
0.54
480
4847
17
136
1.25
0.33
1.7
3.0
14.68
14.95
ml/dl
0.17
17
128
15
118
1.27
0.33
1.0
1.1
94.19
79.92
ug/l
—
10
97
435
4513
0.96
0.33
3.8
3.4
4.45
4.48
pmol/l
0.27
393
4019
356
3416
1.04
0.33
3.6
3.4
45.74
52.10
u/ml
0.21
348
3289
61
548
1.11
0.33
1.2
1.1
—
—
—
0
0
106
1146
0.92
0.33
1.1
1.1
1.35
1.45
u/ml
0.05
52
538
46
406
1.13
0.33
2.1
2.3
17.78
29.91
umol/l
—
5
39
12
155
0.77
0.33
6.0
6.8
—
—
—
0
0
14
177
0.79
0.33
1.4
1.6
—
—
—
0
0
131
1403
0.93
0.32
1.1
1.1
1.09
1.95
u/ml
1.43
67
670
10
74
1.35
0.32
1.0
1.1
—
—
—
0
0
116
1247
0.93
0.32
1.1
1.1
—
—
—
0
0
626
6443
0.97
0.31
2.5
2.2
11.89
12.84
nmol/l
2.18
566
5791
166
1565
1.06
0.31
1.2
1.2
1.44
3.49
u/ml
0.89
14
118
38
432
0.88
0.30
1.0
1.1
0.57
1.83
u/ml
0.80
18
134
23
193
1.19
0.30
1.1
1.5
552.57
411.42
mu/l
0.60
23
184
37
324
1.14
0.30
14.3
10.6
—
—
—
0
0
1321
12969
1.02
0.30
3.2
3.1
2.45
2.45
mmol/l
0.74
1130
11346
13
102
1.27
0.30
11.8
11.8
6.38
5.47
mmol/l
0.28
13
102
24
203
1.18
0.29
3.9
1.6
—
—
—
0
0
88
812
1.08
0.29
2.0
1.7
—
—
—
0
0
303
2908
1.04
0.29
1.3
1.3
1.51
1.04
u/ml
0.19
26
269
230
2193
1.05
0.29
1.3
1.2
203.53
114.06
titre
0.57
17
197
99
1065
0.93
0.29
1.6
1.5
—
—
—
0
0
295
2832
1.04
0.29
2.4
2.2
3.62
3.70
g/l
0.52
268
2586
151
1600
0.94
0.28
1.2
1.3
3.82
3.81
mmol/l
0.03
144
1494
156
1473
1.06
0.28
1.2
1.3
—
—
—
0
0
41
364
1.13
0.28
1.1
1.1
—
—
—
0
0
7480
74536
1.02
0.28
4.3
4.3
1.43
1.44
mmol/l
3.27
6948
69384
124
1164
1.07
0.27
1.5
1.4
—
—
—
0
0
208
1983
1.05
0.27
1.1
1.1
—
—
—
0
0
786
7681
1.03
0.27
1.4
1.4
—
—
—
0
0
56
508
1.10
0.27
2.4
2.6
0.19
0.22
e9/l
0.41
49
436
397
4104
0.97
0.27
1.6
1.7
—
—
—
0
0
144
1360
1.06
0.27
1.7
1.5
—
—
—
0
0
23
196
1.17
0.27
1.1
1.5
72.74
72.66
%
0.01
23
187
499
4848
1.03
0.26
1.2
1.2
—
—
—
0
0
62
567
1.09
0.26
1.1
1.1
433.86
274.67
mg/l
0.92
53
490
32
363
0.88
0.26
1.2
1.2
—
—
—
0
0
5
71
0.70
0.26
1.0
1.1
—
—
—
0
0
148
1562
0.95
0.26
1.5
1.4
—
—
—
0
0
26
225
1.16
0.26
2.1
1.4
—
—
—
0
0
20
169
1.18
0.25
1.1
1.2
207.64
312.66
pmol/l
1.87
14
122
18
213
0.84
0.25
1.6
1.5
9.11
9.01
ug/l
0.07
18
213
92
859
1.07
0.25
2.4
2.1
36.31
23.51
mg/l
0.94
29
221
13
105
1.24
0.24
1.0
1.1
0.07
1.59
u/ml
—
7
76
84
782
1.07
0.24
2.1
1.5
34.33
27.92
iu/ml
—
6
39
122
1151
1.06
0.24
1.2
1.2
3.75
4.32
u/ml
0.16
48
510
687
6716
1.02
0.24
2.2
2.3
385.22
368.68
nmol/l
0.67
642
6172
23
198
1.16
0.24
1.4
1.3
42.54
38.48
%
0.16
13
129
33
371
0.89
0.24
2.0
2.2
68.50
160.71
ug/min
—
8
89
7307
72828
1.02
0.24
4.5
4.4
5.99
5.94
mmol/l
2.12
6706
66966
1044
10258
1.02
0.24
1.2
1.2
—
—
—
0
0
21
180
1.17
0.23
1.0
1.1
—
—
—
0
0
21
180
1.17
0.23
1.0
1.1
—
—
—
0
0
21
180
1.17
0.23
1.0
1.1
—
—
—
0
0
38
341
1.11
0.23
1.7
1.8
76.14
145.28
umol/l
2.36
14
174
114
1207
0.94
0.23
1.4
1.4
73.78
63.31
mmol/l
1.56
91
958
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
22
190
1.16
0.23
1.0
1.0
8.96
11.25
u/ml
0.11
11
117
5
39
1.28
0.23
1.0
1.0
0.12
0.69
u/ml
—
5
33
5
39
1.28
0.23
1.2
1.2
—
—
—
0
0
35
390
0.90
0.22
1.2
1.2
—
—
—
0
0
67
722
0.93
0.22
1.3
1.5
—
—
—
0
0
13
157
0.83
0.22
1.5
2.1
—
—
—
0
0
96
1020
0.94
0.22
1.5
1.4
—
—
—
0
0
69
742
0.93
0.22
1.6
1.4
280.38
280.01
mosm/kgh2o
0.03
52
586
5
41
1.22
0.22
1.4
1.1
—
—
—
0
0
50
458
1.09
0.22
6.2
6.6
—
—
—
0
0
7526
75048
1.01
0.21
4.4
4.3
4.65
4.68
mmol/l
1.18
7033
70221
30
267
1.12
0.21
1.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.18
—
0
5
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
2206
22282
0.99
0.21
4.0
4.1
21.76
21.86
%
0.11
1039
10419
5
43
1.16
0.21
1.6
2.0
2.06
2.83
mg/l
—
5
34
316
3257
0.97
0.21
1.9
1.9
—
—
—
0
0
531
5190
1.02
0.21
2.3
2.4
21.18
24.23
au/ml
0.27
40
426
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
75.98
—
0
13
10
80
1.25
0.20
1.5
1.2
7.38
10.39
mg/l
—
10
73
97
1026
0.94
0.20
1.5
1.4
—
—
—
0
0
63
586
1.08
0.20
1.1
1.1
65.10
42.46
mg/l
1.07
55
485
9
112
0.80
0.20
1.2
1.7
—
—
—
0
0
599
5869
1.02
0.19
1.6
1.7
—
—
—
0
0
459
4483
1.03
0.19
2.0
1.9
1.12
1.36
g/l
4.03
419
4120
6
52
1.15
0.19
1.2
1.0
—
—
—
0
0
87
822
1.06
0.18
1.2
1.4
—
—
—
0
0
164
1576
1.04
0.18
1.2
1.2
—
—
—
0
0
92
871
1.06
0.18
1.6
1.5
4973.06
2269.50
e6/l
0.39
65
639
26
232
1.12
0.18
1.3
1.1
—
—
—
0
0
57
531
1.07
0.18
1.5
1.3
1.29
2.01
u/ml
0.47
32
298
66
619
1.07
0.18
1.2
1.2
185.00
194.74
titre
0.03
12
114
13
153
0.85
0.18
1.1
1.6
—
—
—
0
0
483
4730
1.02
0.17
1.2
1.3
61.81
56.43
au/ml
0.17
27
271
7
61
1.15
0.17
2.0
1.4
—
—
—
0
0
34
372
0.91
0.17
1.1
1.1
1.20
18.56
u/ml
—
5
32
7
63
1.11
0.17
1.1
1.1
—
—
—
0
0
5
67
0.75
0.17
1.8
1.2
—
—
—
0
0
121
1262
0.96
0.16
1.1
1.1
3.42
5.05
u/ml
0.70
57
613
116
1211
0.96
0.16
1.1
1.1
2.03
1.09
u/ml
0.26
51
486
333
3251
1.03
0.16
1.2
1.2
—
—
—
0
0
54
506
1.07
0.15
1.1
1.1
—
—
—
0
0
143
1483
0.96
0.15
1.3
1.4
—
—
—
0
0
385
3770
1.02
0.15
2.3
2.4
—
—
—
0
0
326
3335
0.98
0.15
1.2
1.1
267.67
227.05
titre
0.16
15
88
40
371
1.08
0.15
1.5
2.2
—
—
—
0
0
103
1075
0.96
0.15
1.1
1.1
1.46
1.52
g/l
1.07
90
982
246
2397
1.03
0.14
5.3
6.2
1.28
1.31
mmol/l
0.33
224
2118
7
88
0.80
0.14
1.7
1.2
—
—
—
0
0
46
430
1.07
0.14
1.2
1.4
52.00
384.86
titre
—
5
35
43
460
0.93
0.14
1.1
1.1
5.91
10.19
iu/ml
1.04
12
112
41
382
1.07
0.14
35.9
25.4
111.13
113.94
ug/l
0.15
36
309
156
1611
0.97
0.14
1.4
1.4
265.25
3515.15
e6/l
0.81
122
1302
29
266
1.09
0.13
1.0
1.1
—
—
—
0
0
91
949
0.96
0.13
1.2
1.3
75.27
62.68
u/ml
—
7
67
57
540
1.06
0.12
1.1
1.1
—
—
—
0
0
523
5305
0.98
0.12
1.5
1.4
—
—
—
0
0
815
8240
0.99
0.11
1.6
1.6
—
—
—
0
0
195
1903
1.03
0.11
2.4
2.5
—
—
—
0
0
164
1684
0.97
0.11
2.3
2.9
33.92
35.22
umol/l
0.26
156
1524
39
414
0.94
0.11
1.3
1.4
—
—
—
0
0
157
1611
0.97
0.10
1.3
1.4
18.33
29.06
e6/l
0.49
116
1234
75
780
0.96
0.10
1.4
1.3
2.78
3.00
g/l
0.55
52
553
536
5294
1.01
0.10
3.3
2.9
5.31
4.86
e9/l
0.34
437
4303
75
779
0.96
0.10
1.4
1.3
6.19
6.75
g/l
0.74
53
550
75
779
0.96
0.10
1.4
1.3
0.57
0.41
g/l
0.37
54
553
5275
52874
0.99
0.09
3.7
3.6
—
—
—
0
0
2802
27903
1.01
0.09
4.5
4.7
2.75
3.10
ug/l
0.48
2501
25149
71
684
1.04
0.09
1.3
1.4
9.73
3.42
ug/l
0.52
60
583
122
1253
0.97
0.09
1.5
1.4
—
—
—
0
0
33
350
0.94
0.09
1.1
1.1
—
—
—
0
0
75
777
0.96
0.09
1.3
1.4
—
—
—
0
0
32
301
1.06
0.09
1.9
2.1
—
—
—
0
0
115
1119
1.03
0.09
1.3
1.3
31.72
28.82
u/l
0.41
98
919
6
54
1.11
0.09
1.0
1.1
—
—
—
0
0
6
55
1.09
0.08
6.5
3.5
26.50
35.74
g/mol
—
6
48
70
725
0.97
0.08
3.6
3.0
70.20
51.07
mg/l
0.30
48
531
15
136
1.10
0.08
1.3
1.2
1.55
1.66
mmol/l
—
10
84
185
1814
1.02
0.08
3.8
4.0
—
—
—
0
0
65
674
0.96
0.08
4.9
5.0
154.82
58.70
u/ml
0.68
22
210
19
175
1.09
0.08
1.5
1.4
27.79
22.48
%
0.32
14
145
28
263
1.06
0.08
1.0
1.1
—
—
—
0
0
165
1684
0.98
0.08
1.2
1.2
—
—
—
0
0
5
64
0.78
0.08
1.2
1.5
37.00
41.89
umol/l
—
5
64
106
1088
0.97
0.08
1.1
1.2
—
—
—
0
0
21
195
1.08
0.08
1.6
2.2
18123.64
238.87
e6/l
0.73
11
106
33
348
0.95
0.08
1.9
1.5
—
—
—
0
0
12
133
0.90
0.07
1.6
1.4
—
—
—
0
0
15
137
1.10
0.07
1.2
1.2
—
—
—
0
0
62
641
0.97
0.07
3.8
3.8
29.21
41.55
u/ml
1.01
62
635
7
83
0.84
0.07
1.3
1.4
68.29
77.00
%
—
7
69
118
1206
0.98
0.07
1.7
1.5
—
—
—
0
0
13
118
1.10
0.07
1.0
1.1
—
—
—
0
0
10
89
1.12
0.06
5.5
7.8
—
—
—
0
0
354
3501
1.01
0.06
1.4
1.3
28.86
31.26
iu/l
0.69
302
3013
189
1861
1.02
0.06
2.0
1.9
198.42
201.25
pmol/l
0.13
180
1763
610
6054
1.01
0.06
2.7
2.9
210.98
195.92
ng/l
0.15
544
5495
104
1018
1.02
0.06
1.1
1.1
3.14
3.31
u/ml
0.04
57
499
29
276
1.05
0.06
1.2
1.1
—
—
—
0
0
79
771
1.02
0.05
1.7
1.5
—
—
—
0
0
177
1795
0.99
0.05
1.2
1.3
—
—
—
0
0
180
1825
0.99
0.05
1.3
1.3
585.62
529.03
mg/l
0.57
171
1731
253
2557
0.99
0.05
1.9
1.8
38.04
40.40
nmol/l
0.79
247
2484
2827
28335
1.00
0.05
2.8
2.8
—
—
—
0
0
208
2057
1.01
0.04
2.1
2.0
10.79
11.38
mg/l
0.48
192
1925
104
1058
0.98
0.04
1.5
1.4
0.36
0.36
nmol/l
0.01
83
798
97
953
1.02
0.04
1.1
1.1
—
—
—
0
0
359
3617
0.99
0.04
3.4
3.4
—
—
—
0
0
69
705
0.98
0.04
1.4
1.3
1.66
1.47
nmol/l
0.53
60
634
24
251
0.96
0.04
1.0
1.1
—
—
—
0
0
49
502
0.98
0.03
1.1
1.1
—
—
—
0
0
40
389
1.03
0.03
1.2
1.2
—
—
—
0
0
80
787
1.02
0.03
1.7
1.4
65955.98
65535.10
e6/l
0.00
44
475
17
179
0.95
0.03
1.0
1.1
—
—
—
0
0
125
1264
0.99
0.03
1.8
1.6
0.61
0.80
g/l
1.67
95
974
46
450
1.02
0.02
1.1
1.0
—
—
—
0
0
33
321
1.03
0.02
3.8
2.7
—
—
—
0
0
16
168
0.95
0.02
1.3
2.6
—
—
—
0
0
127
1280
0.99
0.01
1.1
1.1
—
—
—
0
0
1969
19668
1.00
0.01
1.7
1.6
1.43
1.40
mmol/l
0.79
1643
16610
80
809
0.99
0.01
1.1
1.1
—
—
—
0
0
74
748
0.99
0.01
1.9
2.0
—
—
—
0
0
43
423
1.02
0.01
1.2
1.2
—
—
—
0
0
76
767
0.99
0.01
2.6
3.5
57.19
57.11
%
0.01
63
653
77
777
0.99
0.01
1.4
1.4
—
—
—
0
0
11
104
1.06
0.01
1.0
1.1
—
—
—
0
0
18
186
0.97
0.00
1.1
1.1
0.41
1.22
u/ml
0.88
12
95
280
2807
1.00
0.00
2.5
2.7
—
—
—
0
0
30
294
1.02
0.00
2.3
2.8
26.90
28.45
umol/l
0.46
20
211
10
101
0.99
0.00
1.1
1.2
0.10
0.12
u/ml
—
10
101
39
393
0.99
0.00
2.1
1.5
12.66
7.98
ug/l
0.32
32
346
71
705
1.01
0.00
1.5
2.1
13.83
7.23
umol/l
0.47
54
502
19
190
1.00
0.00
6.3
7.0
—
—
—
0
0
12
122
0.98
0.00
2.2
2.3
6.35
4.23
ug/l
—
6
42
17
170
1.00
0.00
1.6
1.2
—
—
—
0
0
13
132
0.98
0.00
2.1
2.9
—
—
—
0
0
12
116
1.03
0.00
4.5
6.7
—
—
—
0
0
18
178
1.01
0.00
1.0
1.0
—
—
—
0
0
44
442
1.00
0.00
1.1
1.1
1.08
1.05
ratio
1.40
20
141
20
205
0.98
0.00
1.5
1.1
—
—
—
0
0
127
1271
1.00
0.00
1.1
1.1
—
—
—
0
0
45
447
1.01
0.00
4.0
3.8
—
—
—
0
0
68
684
0.99
0.00
1.5
1.5
—
—
—
0
0
10
103
0.97
0.00
1.1
1.6
7.54
7.28
mmol/l
—
5
38
10
96
1.04
0.00
1.4
1.2
—
—
—
0
0
15
151
0.99
0.00
5.0
4.5
39.33
74.12
u/l
1.44
15
145
0
6
0.00
0.00
0.0
1.0
—
0.43
—
0
6
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
76.58
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
66
0.91
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
20.78
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1.82
—
0
5
7
78
0.90
-0.00
2.4
2.3
25.93
21.02
mg/l
—
7
71
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.2
—
2.23
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
11.63
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
1470.00
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
38.18
—
0
5
7
77
0.91
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.0
—
—
—
0
0
7
75
0.93
-0.00
1.0
1.1
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
1.6
2.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint APPENDACUT_COMPLIC and mortality.

Females

Parameter HR [95% CI] p-value
APPENDACUT_COMPLIC 1.249 [1.12, 1.4] < 0.001
Birth year 0.992 [0.98, 1.0] 0.049

During the follow-up period (1.1.1998 — 31.12.2019), 1325 out of 13079 females with APPENDACUT_COMPLIC died.

Males

Parameter HR [95% CI] p-value
APPENDACUT_COMPLIC 1.119 [1.01, 1.25] 0.04
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 1714 out of 14440 males with APPENDACUT_COMPLIC died.

Mortality risk

Mortality risk for people of age

years, who have APPENDACUT_COMPLIC.

N-year risk Females Males
1 0.088% 0.216%
5 0.567% 1.277%
10 1.541% 3.117%
15 2.994% 5.806%
20 5.332% 10.039%

Relationships between endpoints

Index endpoint: APPENDACUT_COMPLIC – Acute appendicitis, with complications

GWS hits: 5

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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