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This is a non-core endpoint: only basic statistics are computed.

Mantle cell lymphoma

C3_MANTLE_CELL_LYMPHOMA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C83.1
  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 9673
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

317

4. Check minimum number of events

None

317

5. Include endpoints

None

317

6. Filter based on genotype QC (FinnGen only)

308

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 308 70 238
Unadjusted period prevalence (%) 0.09 0.02 0.11
Median age at first event (years) 70.51 69.49 70.81

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
317
Matched controls
3170
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
1434.5
307.7
287
21
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
307.7
316
*
XW000
NOMESCO Finland
Bone marrow biopsy
100.4
307.7
182
42
WW500
NOMESCO Finland
Blood transfusion
107.2
279.6
149
26
A03FA01
ATC
metoclopramide; systemic, rectal
35.6
242.3
207
159
JN4BD
NOMESCO Finland
Extensive body CT
37.0
218.8
160
85
A04AA01
ATC
ondansetron; systemic, rectal
79.3
205.0
113
22
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
178.5
154
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
2751.2
168.6
148
*
L03AA02
ATC
filgrastim; parenteral
2615.4
163.4
144
*
M04AA01
ATC
allopurinol; systemic
18.6
157.8
222
354
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
26.2
152.3
120
72
L03AA13
ATC
pegfilgrastim; parenteral
1029.2
138.9
126
*
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
43.9
124.4
77
23
JN4AD
NOMESCO Finland
Body CT examination
17.4
115.6
111
95
9673/3-C42.1
ICD-O-3
Mantle cell lymphoma of bone marrow
+∞
110.0
99
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
43.0
109.9
68
20
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
740.0
109.9
102
*
ZX120
NOMESCO Finland
Intravenous
15.7
103.9
105
97
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
102.8
93
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
10.6
94.0
139
217
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
30.0
85.6
59
24
A04AA02
ATC
granisetron; systemic, transdermal
+∞
83.0
76
*
WW300
NOMESCO Finland
Transfer of autologic stem cells
+∞
80.7
74
*
JN6AD
NOMESCO Finland
CT of torso and neck
209.4
79.2
79
5
H02AB02
ATC
dexamethasone; systemic
133.2
77.1
80
8
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
12.7
74.0
82
85
D70.82
ICD-10 Finland
Drug-induced neutropenia
444.1
71.7
69
*
Z51.5
ICD-10 Finland
Palliative care
15.5
71.6
68
55
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
157.3
71.4
73
6
R50.9
ICD-10 Finland
Fever, unspecified
7.9
69.0
129
254
9673/3-C77.9
ICD-O-3
Mantle cell lymphoma of lymph node, NOS
+∞
67.1
62
*
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
22.3
66.3
51
27
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
63.7
59
*
1XC02, ,
NOMESCO Finland
240.6
59.3
59
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
58.1
54
*
WZC00
NOMESCO Finland
Treatment plan or consultation
6.2
57.9
162
460
PJA10
NOMESCO Finland
Exploration of lymph nodes
339.0
57.2
56
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
53.7
50
*
XX3DW
NOMESCO Finland
Time consuming IT work
11.2
51.8
60
65
9673/3-C77.8
ICD-O-3
Mantle cell lymphoma of lymph nodes of multiple regions
+∞
50.4
47
*
H02AB06
ATC
prednisolone; systemic
6.4
49.8
242
1064
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
90.3
48.7
53
7
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
13.6
47.4
47
40
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
47.1
44
*
212
Kela drug reimbursment
Gout
13.3
45.7
46
40
TGC00
NOMESCO Finland
Bronchial lavation
12.4
45.5
48
45
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
505.2
45.4
44
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
14.1
44.5
43
35
WF049
NOMESCO Finland
Radiotherapy of metastasis
491.8
44.4
43
*
J05AB11
ATC
valaciclovir; oral
6.0
44.1
99
224
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
41.6
39
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
439.1
40.0
39
*
390
Kela drug reimbursment
Ibrutinib
+∞
38.3
36
*
ZX112
NOMESCO Finland
Subcutaneous
70.7
38.2
43
7
J01MA12
ATC
levofloxacin; systemic
4.7
37.4
120
362
N02AA05
ATC
oxycodone; systemic
5.1
37.3
101
266
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
37.2
35
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
36.1
34
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
9.9
35.8
44
51
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
7.6
34.8
54
83
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
85.7
34.7
38
5
WW409
NOMESCO Finland
Other aferesis
+∞
34.0
32
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.4
33.7
80
187
WZC30
NOMESCO Finland
Teaching
5.1
33.1
86
217
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
32.9
31
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
52.1
31.4
37
8
WF002
NOMESCO Finland
Radical radiotherapy
118.2
30.3
32
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.0
30.0
217
1119
1512
Kela drug reimbursment
Ibrutinib
+∞
29.6
28
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
159.0
28.1
29
*
WW402
NOMESCO Finland
Leucoferesis
+∞
27.5
26
*
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
+∞
27.5
26
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.5
25.9
56
119
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
25.3
24
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
25.3
24
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
25.3
24
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.4
25.1
152
678
GD1AD
NOMESCO Finland
Thorax CT examination
6.3
24.2
44
79
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
258.7
24.0
24
*
D64.9
ICD-10 Finland
Anaemia, unspecified
4.1
23.6
77
228
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
58.7
23.4
27
5
ZX108
NOMESCO Finland
Inhalation
58.7
23.4
27
5
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
4.6
22.9
62
159
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
29.9
22.7
30
11
116
Kela drug reimbursment
Prostate cancer
+∞
22.1
21
*
L01EL01
ATC
ibrutinib; oral
+∞
22.1
21
*
R06AE07
ATC
cetirizine; oral
3.1
21.9
147
686
YNB10
NOMESCO Finland
Collection of stem cells for transplant
+∞
21.1
20
*
WW200
NOMESCO Finland
Immunization
9.4
20.9
26
30
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
45.1
20.8
25
6
A02BC02
ATC
pantoprazole; systemic
3.7
20.7
253
1640
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
20.0
19
*
9673/3-C09.9
ICD-O-3
Mantle cell lymphoma of tonsil, NOS
+∞
20.0
19
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
19.8
102
404
EP1AE
NOMESCO Finland
Neck ultrasound examination
7.0
19.6
31
48
L01AA02
ATC
chlorambucil; oral
+∞
18.9
18
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
201.4
18.7
19
*
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
+∞
17.9
17
*
L01XE27
ATC
[U] ibrutinib
+∞
17.9
17
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
44.8
17.5
21
5
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.5
17.3
46
115
D70.89
ICD-10 Finland
Neutropenic splenomegaly
67.1
16.9
19
*
L02AE02
ATC
leuprorelin; implant, parenteral
+∞
16.8
16
*
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
179.0
16.7
17
*
H02AB07
ATC
prednisone; oral
3.4
16.4
71
250
D69.5
ICD-10 Finland
Secondary thrombocytopenia
+∞
15.8
15
*
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
+∞
15.8
15
*
1AA09, ,
NOMESCO Finland
+∞
15.8
15
*
J01MA14
ATC
moxifloxacin; systemic
3.9
15.6
50
144
B01AB10
ATC
tinzaparin; parenteral
4.3
15.2
42
108
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
6.9
15.1
24
37
TDM10
NOMESCO Finland
Puncture of maxillary antrum
6.3
15.0
26
44
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
59.6
14.9
17
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
84.1
14.7
16
*
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
+∞
14.7
14
*
YNB00
NOMESCO Finland
Excision of bone marrow for transplantation
+∞
14.7
14
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
14.7
14
*
EMA10
NOMESCO Finland
Biopsy of tonsil
156.9
14.6
15
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.7
14.4
35
81
ZXE00
NOMESCO Finland
One hour or less
2.5
13.7
142
784
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
3.1
13.6
68
259
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
+∞
13.6
13
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
13.6
13
*
L02BB03
ATC
bicalutamide; oral
+∞
13.6
13
*
WX110
NOMESCO Finland
Infiltration anesthesia
2.6
13.6
225
1532
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
146.0
13.6
14
*
B02.9
ICD-10 Finland
Zoster without complication
4.0
13.4
41
114
JN4CD
NOMESCO Finland
Very extensive body CT
12.3
13.0
23
20
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
+∞
12.6
12
*
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
12.6
12
*
130
Kela drug reimbursment
Malignant tumour
+∞
12.6
12
*
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
28.0
12.2
16
6
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.9
11.7
36
100
Z52.89
ICD-10 Finland
Donor of other organ or tissue
+∞
11.5
11
*
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
62.1
10.7
12
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.4
10.5
91
454
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
113.6
10.5
11
*
JN3AD
NOMESCO Finland
Abdominal CT examination
3.2
10.5
45
156
XX9CD
NOMESCO Finland
Very extensive complementary CT
+∞
10.5
10
*
C83.00
ICD-10 Finland
Lymphocytic lymphoma
+∞
10.5
10
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
10.5
10
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
10.5
10
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
10.5
10
*
R05
ICD-10 Finland
Cough
2.5
10.0
76
357
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
20.8
9.9
14
7
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
9.8
87
438
B01AB05
ATC
enoxaparin; parenteral
2.2
9.8
108
596
EMB10
NOMESCO Finland
Tonsillectomy
8.5
9.5
20
25
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
103.0
9.5
10
*
9673/3-C80.9
ICD-O-3
Mantle cell lymphoma of unknown primary site
+∞
9.4
9
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
9.4
9
*
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
+∞
9.4
9
*
C81.3
ICD-10 Finland
Lymphocyte depleted classical Hodgkin lymphoma
+∞
9.4
9
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
9.4
9
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.3
9.4
91
475
J01DB01
ATC
cefalexin; oral
2.5
9.3
260
2045
A07AA02
ATC
nystatin; oral
3.9
9.2
28
77
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.9
9.1
27
73
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.8
9.0
48
188
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.2
8.9
108
614
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.0
8.7
160
1060
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
28.4
8.5
11
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
28.4
8.5
11
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.7
8.5
20
45
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
4.7
8.5
20
45
Y77
ICPC
Malignant neoplasm prostate
92.4
8.5
9
*
TPJ00
NOMESCO Finland
Biopsy of superficial lymph node
92.4
8.5
9
*
A79
ICPC
Malignancy NOS
+∞
8.4
8
*
B72
ICPC
Hodgkin Lymphoma
+∞
8.4
8
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
8.4
8
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
8.4
8
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
8.4
8
*
N05CF01
ATC
zopiclone; oral
2.1
8.1
114
681
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
34.3
8.1
10
*
UJF32
NOMESCO Finland
Coloscopy
2.1
8.1
91
501
L57.0
ICD-10 Finland
Actinic keratosis
2.9
7.9
39
146
J05AB01
ATC
aciclovir; systemic
2.3
7.9
70
349
ED1AA
NOMESCO Finland
Mandibular X-ray examination
46.1
7.7
9
*
J01MA02
ATC
ciprofloxacin; systemic
2.0
7.6
133
855
J12.8
ICD-10 Finland
Other viral pneumonia
25.7
7.6
10
*
C03CA01
ATC
furosemide; systemic
2.0
7.6
132
848
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
81.9
7.4
8
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
81.9
7.4
8
*
D10.4
ICD-10 Finland
Benign neoplasm: Tonsil
81.9
7.4
8
*
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
81.9
7.4
8
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
7.4
103
610
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
6.5
7.4
18
29
1CX01, ,
NOMESCO Finland
+∞
7.3
7
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
7.3
7
*
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
+∞
7.3
7
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.3
7.3
63
310
R4110
NOMESCO Finland
Physiotherapy
2.1
7.3
90
511
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
6.8
7.2
17
26
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
6.3
7.2
18
30
A41.9
ICD-10 Finland
Sepsis, unspecified
3.7
7.0
22
62
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
9.6
6.8
13
14
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.0
6.8
31
111
J35.1
ICD-10 Finland
Hypertrophy of tonsils
17.2
6.8
10
6
NK6AN
NOMESCO Finland
Total body bone isotope imaging
41.0
6.8
8
*
N02BE01
ATC
paracetamol; systemic, rectal
2.5
6.7
278
2356
A41.8
ICD-10 Finland
Other specified sepsis
6.1
6.7
17
29
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
6.7
121
780
HA1AA
NOMESCO Finland
X-ray mammography
8.1
6.7
14
18
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.2
6.7
27
90
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.0
6.6
19
50
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.7
6.5
35
137
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
71.2
6.4
7
*
Z2221
NOMESCO Finland
Medical doctor
2.0
6.4
83
476
SPAT1153
SPAT
Removal of sutures
1.9
6.4
107
670
ZXC50
NOMESCO Finland
Cryotherapy
6.2
6.4
16
27
9673/3-C77.4
ICD-O-3
Mantle cell lymphoma of lymph nodes of inguinal region or leg
+∞
6.3
6
*
9673/3-C77.0
ICD-O-3
Mantle cell lymphoma of lymph nodes of head, face and neck
+∞
6.3
6
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
6.3
6
*
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
+∞
6.3
6
*
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
+∞
6.3
6
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
6.3
6
*
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
+∞
6.3
6
*
WD315
NOMESCO Finland
Multiple therapy of methastized malignancy with biomodifiers
+∞
6.3
6
*
9591/3-C77.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph node, NOS
+∞
6.3
6
*
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
27.3
6.3
8
*
U09.9
ICD-10 Finland
Post COVID-19 condition, unspecified
12.9
6.1
10
8
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
10.3
6.1
11
11
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
6.1
96
589
J20
ICD-10 Finland
Acute bronchitis
2.7
6.0
34
137

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
134
18
128.22
260.52
1.9
1.1
—
—
—
0
0
186
102
42.71
254.05
1.6
1.4
—
—
—
0
0
160
61
51.94
248.32
1.9
1.2
—
—
—
0
0
132
36
62.12
223.57
2.1
1.6
—
—
—
0
0
193
176
26.48
202.79
1.7
1.4
—
—
—
0
0
190
176
25.45
197.34
1.7
1.5
—
—
—
0
0
200
222
22.70
185.49
1.7
1.5
—
—
—
0
0
132
153
14.07
113.39
4.4
1.8
8.42
11.03
g/l
5.13
124
142
135
162
13.77
113.21
6.5
3.6
0.87
0.76
%
0.21
118
47
99
6
238.56
100.92
1.3
1.0
—
—
—
0
0
118
153
11.69
92.07
6.7
3.7
0.16
0.08
%
0.68
98
38
65
33
24.52
86.65
1.4
1.2
—
—
—
0
0
167
353
8.88
85.81
8.0
2.7
0.81
0.83
mmol/l
2.05
162
324
49
12
48.12
82.27
4.3
1.8
359.07
811.92
e6/l
1.36
44
12
108
145
10.78
81.34
6.7
3.7
0.60
0.26
%
2.12
90
39
268
1036
11.27
72.77
15.7
5.4
—
—
—
0
0
263
1009
10.43
71.49
11.9
5.1
0.69
0.65
%
0.41
256
936
266
1039
10.70
70.75
12.3
5.1
2.62
3.04
%
2.17
260
964
266
1047
10.58
69.90
12.8
5.4
10.10
8.93
%
5.42
260
970
266
1065
10.31
68.01
12.7
5.3
30.33
25.75
%
5.04
260
991
145
335
7.13
65.91
3.8
2.0
1.62
1.69
%
0.33
137
301
260
1060
9.08
63.66
11.4
5.1
52.25
58.73
%
9.73
255
990
95
146
8.86
63.04
7.2
3.7
0.21
0.03
%
1.00
76
32
124
256
7.31
62.73
3.9
2.0
62.74
64.40
e9/l
0.22
106
201
263
1126
8.84
59.66
12.0
4.8
0.61
0.62
e9/l
0.21
239
973
263
1130
8.79
59.29
12.0
4.8
0.04
0.04
e9/l
2.47
239
982
265
1147
8.99
59.27
12.2
4.9
1.83
1.78
e9/l
0.19
246
1008
66
71
11.48
57.48
1.4
1.3
—
—
—
0
0
206
726
6.25
57.43
8.6
3.8
—
—
—
0
0
264
1170
8.51
56.47
13.1
4.9
0.17
0.21
e9/l
4.75
247
1020
272
1251
9.27
55.52
38.7
5.7
3.11
4.44
e9/l
31.61
258
1100
83
127
8.50
54.83
2.2
1.3
0.88
1.07
g/l
0.84
75
118
245
1050
6.87
53.16
10.3
3.7
33.99
35.38
g/l
3.37
238
960
43
38
12.93
42.24
2.9
1.4
—
—
—
0
0
245
1193
5.64
41.48
12.4
5.7
1.21
1.21
mmol/l
1.08
208
1021
187
760
4.56
39.63
9.5
2.0
2.34
2.34
mmol/l
0.20
177
625
44
46
10.95
38.60
1.4
1.1
—
—
—
0
0
166
638
4.36
37.48
2.7
1.6
—
—
—
0
0
226
1087
4.76
37.37
10.8
5.2
1.21
1.20
mmol/l
0.61
221
962
171
682
4.27
36.44
9.3
3.2
7.39
7.40
ph
0.92
48
107
36
34
11.82
33.71
1.4
1.0
403.85
303.00
u/ml
0.31
13
19
35
5
78.25
31.58
1.1
1.0
—
—
—
0
0
36
38
10.56
31.20
3.1
1.4
33.64
33.29
pg
0.14
36
38
39
12
36.82
30.81
5.9
2.7
25.69
49.51
%
—
29
7
32
30
11.75
30.02
2.5
3.0
—
—
—
0
0
111
366
4.13
29.92
1.9
1.8
—
—
—
0
0
73
176
5.09
29.41
1.7
1.3
—
—
—
0
0
34
40
9.40
27.14
1.1
1.3
—
—
—
0
0
199
1015
3.58
26.93
6.0
2.4
—
—
—
0
0
130
508
3.64
26.91
24.2
4.2
—
—
—
0
0
37
17
24.47
26.33
5.9
4.0
—
—
—
0
0
156
698
3.43
25.83
6.8
2.2
—
—
—
0
0
32
39
9.01
24.82
1.1
1.1
—
—
—
0
0
192
996
3.35
24.51
22.2
8.3
0.00
0.00
e9/l
0.24
173
811
276
1807
5.08
24.36
27.2
5.3
79.74
76.95
u/l
0.76
271
1648
89
294
3.82
23.32
1.7
1.5
—
—
—
0
0
79
243
4.00
22.89
7.6
2.3
4.73
8.59
umol/l
4.11
72
211
125
536
3.20
21.44
6.1
2.2
—
—
—
0
0
32
18
19.62
21.36
2.9
2.4
—
—
—
0
0
28
35
8.68
21.22
5.5
2.3
51.79
60.06
%
1.34
28
35
50
114
5.02
21.20
2.1
1.4
2.84
2.60
ug/l
0.16
40
91
102
391
3.37
21.03
2.1
1.2
1.94
2.95
g/l
5.20
83
226
81
268
3.72
20.98
4.3
3.4
1.99
1.98
mmol/l
0.01
69
222
70
214
3.91
20.29
6.4
7.4
—
—
—
0
0
124
549
3.07
19.86
1.6
1.3
—
—
—
0
0
59
163
4.22
19.63
1.6
1.1
—
—
—
0
0
149
738
2.92
19.36
3.9
3.0
23.06
139.71
e6/l
0.74
120
571
261
1768
3.70
18.97
7.7
4.0
16.38
12.41
mm/h
3.05
250
1586
137
655
2.92
18.92
3.6
2.7
—
—
—
0
0
28
16
19.06
18.61
1.5
1.2
—
—
—
0
0
114
510
2.93
17.57
2.9
2.1
2.89
3.67
e6/l
0.68
103
453
138
685
2.80
17.46
3.8
2.8
0.21
0.49
e6/l
2.05
111
515
236
1547
3.06
17.29
5.4
4.1
2.43
992.00
e6/l
—
7
26
231
1501
2.99
17.12
7.6
4.3
6.55
6.86
mmol/l
1.88
226
1400
157
845
2.70
16.78
4.6
3.4
45.63
104.52
e6/l
1.31
124
611
108
493
2.81
15.78
3.0
2.6
535.04
572.75
mosm/kgh2o
0.97
97
406
28
51
5.93
15.06
1.8
3.5
—
—
—
0
0
22
33
7.09
14.21
1.1
1.0
—
—
—
0
0
40
105
4.22
14.09
1.5
1.2
—
—
—
0
0
21
13
17.19
13.65
1.1
1.1
—
—
—
0
0
196
1275
2.41
12.76
16.8
17.5
1.29
1.41
inr
0.94
61
351
54
191
3.20
12.21
4.7
3.5
7.46
7.40
ph
2.68
12
19
22
22
10.66
11.70
1.0
1.0
—
—
—
0
0
31
77
4.35
11.69
1.3
1.3
59.08
56.23
mg/l
0.07
25
62
31
78
4.30
11.50
1.3
1.3
34.01
40.13
mg/l
0.32
23
64
15
6
26.12
11.24
1.1
1.2
—
—
—
0
0
53
196
3.05
11.08
4.8
3.4
4.97
5.21
kpa
1.47
53
187
14
5
29.17
10.81
1.9
1.8
—
—
—
0
0
15
8
19.60
10.36
1.5
1.3
—
—
—
0
0
22
28
8.36
10.29
1.0
1.2
—
—
—
0
0
39
125
3.42
10.28
1.5
1.6
1.60
1.50
g/l
0.21
30
107
147
908
2.15
10.06
3.2
2.6
502.82
162.58
ug/l
6.54
134
818
23
53
4.60
9.50
3.4
2.5
—
—
—
0
0
21
47
4.71
8.97
2.7
2.0
14.59
16.27
%
1.53
15
29
112
647
2.13
8.88
2.0
2.1
3.06
2.91
mg/l
0.30
94
539
79
396
2.33
8.88
3.6
2.9
0.85
1.80
e6/l
1.08
44
223
25
65
4.09
8.87
1.4
1.2
—
—
—
0
0
116
681
2.11
8.81
3.9
3.0
—
—
—
0
0
63
289
2.47
8.61
2.2
1.7
—
—
—
0
0
141
905
2.01
8.28
3.2
3.2
1341.82
1734.57
ng/l
0.79
130
774
221
1663
2.09
8.23
5.1
4.0
—
—
—
0
0
51
217
2.61
8.13
1.4
1.3
—
—
—
0
0
11
5
22.71
8.07
3.1
1.4
24.95
33.48
u/l
—
11
5
19
45
4.43
7.58
3.2
3.7
1.73
2.26
mmol/l
0.44
11
22
37
138
2.90
7.56
5.5
3.7
—
—
—
0
0
21
55
4.02
7.38
1.2
1.2
—
—
—
0
0
86
481
2.08
7.23
2.3
1.7
1.84
1.37
mg/l
0.42
77
374
21
56
3.95
7.20
2.9
2.4
—
—
—
0
0
10
5
20.58
7.17
1.2
1.0
—
—
—
0
0
28
93
3.21
6.96
1.3
1.2
—
—
—
0
0
51
237
2.37
6.71
7.3
3.5
—
—
—
0
0
24
76
3.33
6.44
1.9
1.3
37.10
36.69
g/l
0.12
24
64
161
1152
1.81
6.24
3.9
3.6
0.00
0.00
estimate
0.50
51
210
136
925
1.82
6.24
3.3
3.4
5.90
5.78
ph
—
5
55
160
1145
1.80
6.18
5.0
4.9
0.00
0.00
estimate
-0.00
49
193
278
2384
2.35
6.06
52.5
13.6
22.41
26.53
mg/l
2.02
270
1835
161
1167
1.77
5.85
4.0
3.6
0.00
0.00
estimate
-0.00
50
187
42
192
2.37
5.72
5.0
3.0
—
—
—
0
0
8
5
16.35
5.44
3.8
1.0
—
—
—
0
0
5
0
+∞
5.22
1.2
0.0
—
—
—
0
0
5
0
+∞
5.22
1.2
0.0
—
—
—
0
0
5
0
+∞
5.22
1.0
0.0
—
—
—
0
0
5
0
+∞
5.22
1.2
0.0
—
—
—
0
0
115
776
1.76
5.22
2.5
2.3
51.76
63.37
u/l
1.13
110
710
12
20
6.19
4.96
1.3
1.0
—
—
—
0
0
87
556
1.78
4.69
3.2
3.9
122.91
361.34
ng/l
1.57
77
471
17
54
3.27
4.55
1.1
1.3
284.00
316.41
ug/g
—
7
30
13
28
4.79
4.42
2.1
1.9
—
—
—
0
0
7
6
11.89
4.29
1.0
1.0
632.14
2566.17
miu/ml
—
7
6
18
62
3.02
4.24
2.6
2.0
114.28
133.31
g/l
3.14
18
45
10
17
6.04
4.16
1.1
1.2
—
—
—
0
0
101
694
1.67
4.13
1.9
1.6
18.43
20.27
nmol/l
0.68
91
579
14
42
3.44
4.09
1.0
1.7
—
—
—
0
0
14
36
4.02
4.05
1.1
1.1
—
—
—
0
0
54
311
1.89
4.03
1.3
1.2
—
—
—
0
0
38
195
2.08
3.93
2.3
2.2
33.56
33.51
u/l
0.00
25
164
8
11
7.43
3.88
1.9
1.9
1331.63
852.82
u/ml
—
8
11
56
332
1.83
3.82
6.9
6.3
1.97
1.31
mmol/l
0.51
42
262
143
1096
1.56
3.62
4.4
4.0
28.53
47.28
ng/l
2.19
126
833
10
21
4.88
3.58
1.3
1.4
90.71
89.01
%
—
10
21
7
10
7.13
3.38
3.4
1.3
2.31
4.75
nmol/l
—
7
10
10
23
4.45
3.33
1.2
1.3
—
—
—
0
0
29
143
2.13
3.33
6.0
2.5
1.18
1.16
%
0.03
29
143
6
7
8.71
3.27
1.3
1.3
—
—
—
0
0
6
7
8.71
3.27
1.2
1.3
—
—
—
0
0
28
138
2.13
3.22
3.8
2.4
0.69
0.65
%
0.35
28
138
204
2330
0.65
3.20
5.5
6.6
41.00
41.03
mmol/mol
0.02
182
2124
87
611
1.58
3.16
4.1
3.2
—
—
—
0
0
89
629
1.58
3.15
4.7
3.8
0.00
0.02
estimate
0.50
45
180
37
208
1.88
2.98
5.2
4.3
—
—
—
0
0
28
144
2.04
2.90
3.1
2.9
6.40
4.93
e9/l
0.22
22
100
7
13
5.48
2.88
1.7
1.3
14.22
12.11
ug/l
—
7
13
12
38
3.24
2.88
1.8
1.8
0.41
1.01
g/l
—
6
32
9
23
4.00
2.79
1.8
1.3
—
—
—
0
0
5
6
8.44
2.76
1.0
1.0
—
—
—
0
0
5
6
8.44
2.76
2.0
1.2
—
—
—
0
0
7
14
5.09
2.74
1.1
1.1
—
—
—
0
0
7
14
5.09
2.74
1.1
1.1
—
—
—
0
0
209
1797
1.48
2.73
5.4
4.2
—
—
—
0
0
9
24
3.83
2.69
2.0
1.2
—
—
—
0
0
24
121
2.06
2.63
5.3
4.1
—
—
—
0
0
10
30
3.41
2.62
1.0
1.1
—
—
—
0
0
5
7
7.23
2.56
1.2
1.0
—
—
—
0
0
105
802
1.46
2.51
4.9
4.1
—
—
—
0
0
9
26
3.53
2.50
1.6
1.3
—
—
—
0
0
7
17
4.19
2.37
3.0
1.6
5481.50
2.46
u/ml
—
7
17
13
54
2.47
2.23
1.2
1.1
—
—
—
0
0
34
205
1.74
2.22
2.0
2.1
193.22
154.06
ug/g
0.27
27
163
11
42
2.68
2.16
1.7
2.5
—
—
—
0
0
42
271
1.63
2.14
1.3
1.3
960.00
530.00
titre
—
5
60
215
2373
0.71
2.11
3.9
4.9
1.31
1.39
mmol/l
2.10
184
2145
0
55
0.00
2.09
0.0
1.2
—
—
—
0
0
174
1489
1.37
2.07
3.6
3.1
60.40
53.85
u/l
0.41
161
1358
74
548
1.46
2.04
3.4
3.7
—
—
—
0
0
7
22
3.23
1.89
1.7
1.6
—
—
—
0
0
5
12
4.21
1.83
2.2
2.3
—
—
—
0
0
6
18
3.38
1.75
1.3
1.3
—
—
—
0
0
267
2486
1.47
1.72
36.4
13.3
—
—
—
0
0
5
13
3.89
1.72
4.4
2.4
—
—
—
0
0
18
97
1.91
1.70
1.8
1.7
—
—
—
0
0
220
2393
0.74
1.69
4.0
4.9
4.55
4.40
mmol/l
1.27
193
2185
48
658
0.68
1.67
2.1
1.7
1.51
1.36
mmol/l
0.56
35
535
227
2456
0.73
1.66
4.4
5.5
2.72
2.57
mmol/l
1.66
193
2225
7
25
2.84
1.66
2.4
1.2
16.71
50.94
u/ml
—
7
25
5
14
3.61
1.62
1.2
1.2
—
—
—
0
0
24
146
1.70
1.56
11.5
8.9
—
—
—
0
0
6
21
2.89
1.51
4.5
2.4
—
—
—
0
0
135
1153
1.30
1.47
2.1
2.1
90.32
93.04
pmol/l
0.35
82
600
279
2641
1.47
1.43
67.5
19.9
185.76
234.39
e9/l
26.54
274
2551
279
2641
1.47
1.43
67.3
20.1
36.55
40.27
%
23.42
265
2408
15
260
0.56
1.42
1.2
1.4
—
—
—
0
0
73
574
1.35
1.42
1.7
1.8
1315.43
1130.30
nmol/l
0.81
57
439
78
962
0.75
1.41
3.4
3.8
15.11
8.60
mg/mmol
0.34
44
628
279
2643
1.46
1.40
67.4
19.9
3.99
4.52
e12/l
36.31
272
2532
279
2644
1.46
1.39
67.3
20.0
6.91
6.77
e9/l
0.11
272
2538
5
17
2.97
1.36
1.8
1.5
9.20
11.18
mmol/l
—
5
17
17
98
1.78
1.34
1.6
2.8
3.94
4.37
pmol/l
1.96
17
85
9
43
2.12
1.31
1.2
1.2
—
—
—
0
0
6
25
2.43
1.25
1.0
1.0
—
—
—
0
0
186
1678
1.26
1.24
3.5
3.4
15.00
15.02
pmol/l
0.05
168
1477
75
907
0.77
1.15
2.9
3.3
78.57
195.21
mg/l
0.57
44
602
77
922
0.78
1.08
2.8
3.1
6.41
7.99
mmol/l
4.54
60
762
215
2299
0.80
1.06
3.9
4.4
1.37
1.28
mmol/l
0.76
186
2062
12
67
1.82
1.06
4.2
3.0
—
—
—
0
0
5
22
2.29
1.03
1.0
1.4
—
—
—
0
0
12
68
1.79
1.02
1.1
1.1
—
—
u/ml
—
0
0
0
29
0.00
0.98
0.0
3.0
—
—
—
0
0
6
118
0.50
0.96
1.3
1.4
—
—
—
0
0
27
194
1.43
0.92
1.3
1.5
—
—
—
0
0
8
43
1.88
0.88
5.5
2.4
—
—
—
0
0
8
45
1.80
0.85
5.5
2.3
4.19
4.12
mmol/l
—
8
45
8
45
1.80
0.85
5.5
2.3
105.13
105.67
mmol/l
—
8
45
10
58
1.75
0.80
2.1
3.0
1.00
0.91
nmol/l
—
5
45
10
59
1.72
0.76
1.1
2.9
—
—
—
0
0
9
55
1.65
0.74
1.2
1.3
12.22
139.04
e6/l
—
9
47
9
55
1.65
0.74
1.2
1.5
258.44
238.31
e6/l
—
9
48
52
433
1.24
0.68
1.1
1.2
0.72
1.53
u/ml
1.79
14
117
70
602
1.21
0.68
1.6
1.8
499.21
410.01
pmol/l
1.08
58
487
15
104
1.46
0.63
1.3
1.3
—
—
—
0
0
12
79
1.54
0.63
3.8
4.2
—
—
—
0
0
11
73
1.53
0.57
1.3
1.2
—
0.26
—
0
8
20
153
1.33
0.51
1.1
1.2
—
—
—
0
0
140
1500
0.88
0.51
4.9
4.0
3.73
2.06
ug/l
0.51
124
1322
28
343
0.80
0.50
1.1
1.2
1.15
12.17
u/ml
2.56
12
123
5
81
0.61
0.46
2.4
2.0
36.80
43.24
nmol/l
—
5
75
68
760
0.87
0.46
3.0
3.4
—
—
—
0
0
7
51
1.38
0.44
1.1
2.3
62.57
67.53
%
—
7
51
0
18
0.00
0.40
0.0
1.8
—
—
—
0
0
32
372
0.84
0.36
1.1
1.2
10.90
35.75
iu/ml
—
7
105
6
45
1.34
0.34
1.2
1.2
—
—
—
0
0
222
2151
1.11
0.33
4.3
4.2
2.26
1.99
mu/l
1.55
202
1908
8
66
1.22
0.27
1.6
1.7
—
—
—
0
0
15
179
0.83
0.23
3.7
3.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
148.67
—
0
12
0
12
0.00
0.21
0.0
1.2
—
224.50
—
0
12
0
13
0.00
0.21
0.0
1.5
—
1.03
—
0
8
0
14
0.00
0.20
0.0
1.5
—
59.63
—
0
8
236
2397
0.94
0.16
5.0
5.1
6.01
6.14
mmol/l
0.94
211
2134
16
141
1.14
0.14
3.2
2.5
—
—
—
0
0
5
60
0.83
0.08
1.2
1.1
—
98.33
—
0
6
25
234
1.07
0.08
3.6
3.0
—
—
—
0
0
7
66
1.06
0.08
1.4
2.3
29.43
31.86
umol/l
—
7
59
17
184
0.92
0.07
1.5
1.5
—
—
—
0
0
53
545
0.97
0.05
4.3
4.0
1.01
1.02
kg/l
—
6
91
14
147
0.95
0.01
4.6
3.5
—
—
—
0
0
13
133
0.98
0.00
1.2
1.3
—
—
—
0
0
14
143
0.98
0.00
1.2
1.2
—
22.53
—
0
11
83
835
0.99
0.00
3.5
2.6
0.73
0.74
ug/l
0.03
61
569
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
-0.00
1.3
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.4
—
—
—
0
0
9
99
0.91
-0.00
24.0
10.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
27.67
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
390.50
—
0
6
0
7
0.00
-0.00
0.0
1.6
—
15.61
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
17.92
—
0
5
0
7
0.00
-0.00
0.0
9.7
—
1012.43
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
29.38
—
0
5
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
11.6
—
1463.43
—
0
7
0
7
0.00
-0.00
0.0
6.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
94
0.96
-0.00
3.7
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
6.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
47144.44
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_MANTLE_CELL_LYMPHOMA – Mantle cell lymphoma

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).