All dysplastic lesions of the cervix uteri

N14_CERVICAL_DYSPLASIA_ALL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D06, N87
  • Hospital discharge: ICD-9 6221A|6221B|6221C|2331A
  • Cause of death: ICD-10 D06, N87
  • Cause of death: ICD-9 6221A|6221B|6221C|2331A

2 out of 7 registries used, show all original rules.

12059

4. Check minimum number of events

None

12059

5. Include endpoints

None

12059

6. Filter based on genotype QC (FinnGen only)

12059

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 76103 76103 -
Only index persons 74438 74438 -
Unadjusted period prevalence (%)
Whole population 2.18 2.18 -
Only index persons 2.74 2.74 -
Median age at first event (years)
Whole population - 34.69 -
Only index persons - 34.52 -

-FinnGen-

Key figures

All Female Male
Number of individuals 12059 12059 -
Unadjusted period prevalence (%) 4.11 4.11 -
Median age at first event (years) 35.33 35.33 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
10697
Matched controls
106899
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N87.9
ICD-10 Finland
Dysplasia of cervix uteri, unspecified
110.1
323.0
413
39
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
+∞
323.0
381
*
ULA02
NOMESCO Finland
Kolposcopy
51.7
323.0
8262
6579
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
46.3
323.0
8128
6843
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
16.8
323.0
561
350
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
267.9
323.0
2314
110
A63.0
ICD-10 Finland
Anogenital (venereal) warts
6.7
323.0
1515
2555
N87.1
ICD-10 Finland
Moderate cervical dysplasia
12995.6
323.0
3562
*
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
164.0
323.0
6041
841
ZXC00
NOMESCO Finland
Use of diathermy
55.1
323.0
490
93
LDA10
NOMESCO Finland
Curettage of cervix uteri
22.8
323.0
3406
2145
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
34.9
323.0
6193
4049
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
5519.0
323.0
3796
10
N87.0
ICD-10 Finland
Mild cervical dysplasia
1546.3
323.0
4115
43
C539, 6666, 0
ICD-O-3
NA
125.1
323.0
1131
101
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
15.0
323.0
6457
9825
8326
FHL
Batch conization
108.3
307.1
336
32
LEB00
NOMESCO Finland
Biopsy of vagina
9.5
302.4
651
725
8070/2-C53.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of cervix uteri
51.0
265.0
322
65
D06.1
ICD-10 Finland
Carcinoma in situ: Exocervix
+∞
254.1
243
*
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
8.0
232.0
550
715
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.9
222.5
5222
35379
6221C
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI GRAVIS]
+∞
217.3
208
*
G01AA10
ATC
clindamycin; vaginal
2.0
188.7
2908
16488
6221B
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI MODERATA]
+∞
183.8
176
*
6221A
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI LEVIS]
+∞
179.6
172
*
8140/2-C53.9
ICD-O-3
Adenocarcinoma in situ, NOS, of cervix uteri
220.1
147.3
152
7
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
4.6
141.6
526
1196
8077/2-C53.1
ICD-O-3
Squamous intraepithelial neoplasia, high grade of exocervix
328.4
129.7
131
*
N89.0
ICD-10 Finland
Mild vaginal dysplasia
18.8
125.4
196
106
D06.9
ICD-10 Finland
Carcinoma in situ: Cervix, unspecified
+∞
124.1
119
*
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
13.3
120.6
216
165
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
11.7
101.5
193
168
X86
ICPC
Abnormal cervix smear
5.4
101.5
322
616
2331A
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Cervix uteri
+∞
99.1
95
*
LCA06
NOMESCO Finland
Biopsy of endometrium
1.8
93.4
1861
11149
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
28.8
83.4
114
40
D06BB04
ATC
podophyllotoxin; topical
2.2
80.3
935
4545
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
80.2
3401
24902
LDC00
NOMESCO Finland
Conisation of cervix uteri using knife
49.8
77.6
94
19
R87.2
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of other drugs, medicaments and biological substances
24.5
75.0
107
44
R87.1
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of hormones
29.6
67.2
91
31
P01AB01
ATC
metronidazole; oral, rectal
1.4
65.1
4510
36113
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.2
61.8
653
3027
R87.0
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of enzymes
21.9
59.1
87
40
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
23.6
57.0
82
35
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.6
57.0
1778
11926
N90.0
ICD-10 Finland
Mild vulvar dysplasia
11.2
55.8
107
96
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1.6
50.2
1599
10742
R87.9
ICD-10 Finland
Abnormal findings in specimens from female genital organs, unspecified abnormal finding
11.4
50.0
95
84
D06BB10
ATC
imiquimod; topical
2.3
48.9
495
2245
C53.11
ICD-10 Finland
Squamous cell carcinoma and exocervix
13.3
46.9
83
63
N87
ICD-10 Finland
Dysplasia of cervix uteri
26.6
44.1
61
23
TLC02
NOMESCO Finland
Simple extraction of IUD
1.8
42.2
756
4296
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
4.6
42.2
151
332
SPAT1193
SPAT
Pap smear
1.5
41.2
1738
12392
LDB10
NOMESCO Finland
Cryotherapy of cervix uteri
6.9
40.3
102
148
R2110
NOMESCO Finland
Giving the first information
1.7
40.1
916
5612
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
10.5
40.0
79
76
8325
FHL
Coagulation, cryo or laser in anesthesia or operating room
9.3
39.9
84
91
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
28.5
39.8
54
19
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
10.8
38.6
75
70
0781C
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Viral warts[CONDYLOMA ACCUMINATUM]
5.2
38.3
121
233
N76.0
ICD-10 Finland
Acute vaginitis
1.6
37.2
1004
6435
X23
ICPC
Fear sexually transm dis female
1.7
36.8
851
5224
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.4
36.5
2491
19369
N07BA03
ATC
varenicline; oral
1.9
36.2
529
2796
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.4
34.3
1666
12166
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
11.3
33.8
64
57
WX110
NOMESCO Finland
Local anesthesy
1.3
33.6
7172
65273
C53.01
ICD-10 Finland
Squamous cell carcinoma of the endocervix
10.9
33.3
64
59
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
32.3
2894
23396
8140/2-C53.0
ICD-O-3
Adenocarcinoma in situ, NOS, of endocervix
+∞
32.3
31
*
O34.4
ICD-10 Finland
Maternal care for other abnormalities of cervix
8.3
31.3
70
85
X92
ICPC
Chlamydia infection genital female
2.7
31.0
223
847
G01AF01
ATC
metronidazole; vaginal
1.5
30.9
1119
7679
LDB00
NOMESCO Finland
Excision of lesion of cervix uteri
2.9
30.7
194
679
8070/3-C53.9
ICD-O-3
Squamous cell carcinoma, NOS, of cervix uteri
10.8
30.6
59
55
N93.0
ICD-10 Finland
Postcoital and contact bleeding
3.3
29.6
152
462
8140/2-C53.1
ICD-O-3
Adenocarcinoma in situ, NOS, of exocervix
150.3
28.6
30
*
C53.02
ICD-10 Finland
Adenocarcinoma of the endocervix
9.5
28.2
58
61
J02AC01
ATC
fluconazole; systemic
1.3
28.2
5290
46831
8076/3-C53.9
ICD-O-3
Squamous cell carcinoma, microinvasive of cervix uteri
77.8
27.7
31
*
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.5
27.7
1114
7811
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
2.2
26.7
265
1195
LCH11
NOMESCO Finland
Pharmacologic abortion
1.6
26.4
720
4612
N72
ICD-10 Finland
Inflammatory disease of cervix uteri
3.4
26.4
130
384
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
5.8
24.9
71
123
M03BX02
ATC
tizanidine; oral
1.2
24.6
6421
58575
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
2.3
23.8
231
1032
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
1.5
23.7
783
5256
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
1.3
23.5
2042
16310
N02AX02
ATC
tramadol; systemic, rectal
1.3
22.4
3079
26058
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
1.8
22.4
425
2457
K05.31
ICD-10 Finland
Periodontitis pronounced
1.6
22.3
540
3349
8140/3-C53.9
ICD-O-3
Adenocarcinoma, NOS, of cervix uteri
15.7
22.3
36
23
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
21.9
2104
17011
SPAT1308
SPAT
Sexual health counselling
1.3
21.9
2008
16141
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
21.5
7515
70161
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
21.4
9631
92832
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.5
21.2
808
5591
N02BE01
ATC
paracetamol; systemic, rectal
1.3
21.1
8402
79497
J01DB01
ATC
cefalexin; oral
1.3
20.9
8287
78300
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.6
20.2
521
3289
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
1.9
19.8
309
1677
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.3
19.6
1298
9930
M54.5
ICD-10 Finland
Low back pain
1.2
19.5
3121
26781
SPAT1283
SPAT
Restricted health certificate
1.3
19.4
2496
20897
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.5
19.0
767
5368
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
18.1
3620
31720
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.2
17.9
3638
31921
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
1.6
17.6
435
2717
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
1.8
17.6
284
1562
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
9.7
17.6
35
36
W11
ICPC
Contraception oral
1.3
17.5
1289
10013
J01CA08
ATC
pivmecillinam; oral
1.2
17.4
5054
45821
X15
ICPC
Vaginal symptom/complaint other
1.6
17.3
479
3083
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
1.2
16.9
2191
18306
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
16.3
4055
36174
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
1.7
16.2
365
2224
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
16.2
4879
44269
J01AA02
ATC
doxycycline; systemic
1.2
16.0
7415
69854
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
16.0
5208
47560
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
15.8
6913
64729
XLA10
NOMESCO Finland
NA
1.5
15.5
571
3922
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
15.4
5415
49696
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
15.2
3820
34037
Z72.0
ICD-10 Finland
Tobacco use
2.0
15.1
204
1055
K02.1
ICD-10 Finland
Caries of dentine
1.2
15.0
5901
54611
Z30.4
ICD-10 Finland
Surveillance of contraceptive drugs
1.3
15.0
968
7359
LCD31
NOMESCO Finland
Radical laparoscopic hysterectomy
7.7
15.0
34
44
WX290
NOMESCO Finland
Other blockade of nerve
1.2
15.0
4858
44236
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
14.9
5269
48328
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
1.6
14.7
420
2725
J05AB01
ATC
aciclovir; systemic
1.2
14.6
1952
16327
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.3
14.6
1383
11103
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
1.6
14.5
344
2128
8010/2-C53.9
ICD-O-3
Carcinoma in situ, NOS, of cervix uteri
150.1
14.5
15
*
Z30.0
ICD-10 Finland
General counselling and advice on contraception
1.3
14.4
916
6949
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
2.4
14.4
120
503
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
14.0
3577
31862
R87.3
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of substances chiefly nonmedicinal as to source
15.7
13.9
22
14
8111
FHL
Taking a biopsy from the mouth of the uterus at the operating room or under anesthesia (vulvabiopsia 8474, vaginabiopsia 8411)
6.8
13.8
34
50
N05CF01
ATC
zopiclone; oral
1.2
13.7
2224
18983
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
1.7
13.7
302
1833
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.4
13.6
800
5992
Z30.2
ICD-10 Finland
Sterilization
1.3
13.5
1258
10072
R74
ICPC
Upper respiratory infection acute
1.2
13.4
3406
30298
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
13.3
5909
54958
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.2
13.1
2310
19869
T36
ICD-10 Finland
Poisoning by systemic antibiotics
1.5
12.9
414
2760
N06AX11
ATC
mirtazapine; oral
1.2
12.9
2677
23374
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.3
12.8
872
6681
1390
FHL
Colposcopy
5.7
12.6
35
61
7950A
ICD-9 Finland
Nonspecific abnormal histological and immunological findings, Nonspecific abnormal Papanicolaou smear of cervix
8.2
12.5
27
33
ULC02
NOMESCO Finland
Hysteroscopy
1.4
12.4
550
3923
D82
ICPC
Teeth/gum disease
1.2
12.4
3502
31370
EBA00
NOMESCO Finland
Extraction of tooth
1.2
12.3
2695
23618
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
1.7
12.3
239
1400
SPAT1312
SPAT
General health counselling
1.2
12.2
2845
25064
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
12.2
220
1260
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.8
12.2
214
1215
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
12.2
3157
28072
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.2
12.1
1949
16589
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.2
12.1
2817
24816
R87.8
ICD-10 Finland
Abnormal findings in specimens from female genital organs, other abnormal findings
3.3
12.1
60
184
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
12.0
5826
54355
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
2.6
11.9
83
315
L04AX01
ATC
azathioprine; systemic
1.6
11.7
328
2124
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
11.6
7163
67951
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
1.5
11.5
389
2628
LDA96
NOMESCO Finland
Other biopsy of cervix uteri
11.1
11.5
21
19
J01DA01
ATC
[U] cefalexin; systemic
1.2
11.5
6060
56794
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.2
11.4
1804
15322
X91
ICPC
Condylomata acuminata female
3.6
11.4
50
140
LCD10
NOMESCO Finland
Vaginal hysterectomy
1.6
11.3
301
1922
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
2.0
11.3
135
669
8327
FHL
Amputation portionis and conization
35.0
11.2
14
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
11.2
3705
33523
M03BC01
ATC
orphenadrine (citrate); systemic
1.2
11.1
2333
20344
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.2
10.9
3415
30765
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
1.2
10.8
1537
12911
C53.12
ICD-10 Finland
Adenocarcinoma of the exocervix
9.6
10.7
21
22
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.2
10.5
2735
24267
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
1.5
10.4
341
2288
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
2.8
10.4
65
232
LDC96
NOMESCO Finland
Other excision of cervix uteri
23.3
10.2
14
6
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.1
10.2
3900
35601
8474
FHL
Coagulation, excision, or biopsy of local change (eg, condyloma, tumor) in operating room or anesthesia
3.4
10.2
47
138
J05AB11
ATC
valaciclovir; oral
1.3
10.0
1091
8898
P01BA02
ATC
hydroxychloroquine; oral
1.3
9.9
636
4834
LCH13
NOMESCO Finland
Vacuum aspiration from uterus after medically induced abortion
1.6
9.9
239
1495
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.2
9.9
1464
12342
8070/3-C53.1
ICD-O-3
Squamous cell carcinoma, NOS, of exocervix
12.2
9.8
17
14
M01AE03
ATC
ketoprofen; systemic, rectal
1.2
9.8
2798
24977
R05
ICPC
Cough
1.2
9.8
1868
16127
SDA02
NOMESCO Finland
Parodonthologic therapy
1.2
9.8
3084
27741
N88.2
ICD-10 Finland
Stricture and stenosis of cervix uteri
4.4
9.8
34
78
SPAT1263
SPAT
Sampling
1.1
9.8
3790
34604
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
1.6
9.7
216
1320
8411
FHL
Local change laser, coagulation, biopsy or removal
4.2
9.6
35
84
N06AB04
ATC
citalopram; systemic
1.2
9.6
1860
16079
Z09.9
ICD-10 Finland
Follow-up examination after unspecified treatment for other conditions
1.9
9.5
127
659
M79.6
ICD-10 Finland
Pain in limb
1.2
9.4
2975
26750
D19
ICPC
Teeth/gum symptom/complaint
1.2
9.4
2472
21917
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.3
9.4
985
7995
D06.7
ICD-10 Finland
Carcinoma in situ: Other parts of cervix
+∞
9.4
9
*
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
0.8
9.4
1184
14063
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.2
9.3
2413
21375
M01AB05
ATC
diclofenac; systemic, rectal
1.1
9.3
6157
58176
WX408
NOMESCO Finland
General anesthesy, balanced
1.2
9.2
1960
17073
W14
ICPC
Contraception female other
1.3
9.2
670
5185
J01MA02
ATC
ciprofloxacin; systemic
1.2
9.2
2654
23698
Z71.8
ICD-10 Finland
Other specified counselling
1.2
9.1
2239
19739
M54.4
ICD-10 Finland
Lumbago with sciatica
1.2
9.1
1337
11255
PJA01
NOMESCO Finland
Laparoscopic sentinel node excision
3.3
9.1
44
135
Z01.2
ICD-10 Finland
Dental examination
1.1
9.0
4014
36930
X85
ICPC
Cervical disease NOS
5.6
9.0
25
45
LDC10
NOMESCO Finland
Partial excision of cervix uteri
7.4
8.9
20
27
A03
ICPC
Fever
1.2
8.9
1587
13615
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
1.4
8.9
414
2988
N30.0
ICD-10 Finland
Acute cystitis
1.2
8.9
1173
9768
4044
NOMESCO Finland
NA
5.7
8.9
24
42
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.3
8.8
863
6952
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
1.4
8.8
392
2806
21899
ICD-8 Finland
Uterine fibroma
0.3
8.8
19
616
N76.1
ICD-10 Finland
Subacute and chronic vaginitis
1.6
8.7
244
1585
SPAT1301
SPAT
No procedures
1.2
8.7
2335
20714
Z87.4
ICD-10 Finland
Personal history of diseases of the genitourinary system
2.0
8.7
111
570
ZXC10
NOMESCO Finland
Use of laser
1.8
8.7
137
757
A02BC02
ATC
pantoprazole; systemic
1.1
8.7
5392
50637
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
1.3
8.6
528
3986
R51.80
ICD-10 Finland
Headache
1.2
8.6
1453
12396
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
1.3
8.6
776
6185
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.3
8.6
650
5063
T74.1
ICD-10 Finland
Physical abuse
1.7
8.6
177
1063
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.2
8.5
928
7563
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.2
8.5
1410
12008
W12
ICPC
Contraception intrauterine
1.2
8.4
1500
12862
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.2
8.4
1624
14026
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
8.4
2452
21893
SPAT1192
SPAT
Gynaecological examination
1.2
8.4
1501
12875
X14
ICPC
Vaginal discharge
1.5
8.3
277
1875
WZA90
NOMESCO Finland
Other doctors statement
1.2
8.3
1881
16465
J01FF01
ATC
clindamycin; systemic
1.2
8.2
2089
18448
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.2
8.2
2182
19336
R21
ICPC
Throat symptom/complaint
1.2
8.2
2250
19988
M03BC51
ATC
orphenadrine, combinations; systemic
1.1
8.1
2617
23525
P01
ICPC
Feeling anxious/nervous/tense
1.2
8.0
1182
9950
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.2
8.0
1198
10100
D01
ICPC
Abdominal pain/cramps general
1.2
7.9
912
7483
C53.00
ICD-10 Finland
Malignant tumor of endocervix without histology
7.7
7.8
17
22
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.1
7.8
3446
31606
J01EA01
ATC
trimethoprim; systemic
1.1
7.7
2408
21578
P17
ICPC
Tobacco abuse
1.9
7.7
107
569
8077/2-C53.0
ICD-O-3
Squamous intraepithelial neoplasia, high grade of endocervix
45.0
7.7
9
*
G01AX03
ATC
policresulen; vaginal
2.0
7.7
89
440
X29
ICPC
Genital sympt/compl female other
1.7
7.7
137
789
KAY40
NOMESCO Finland
NA
0.6
7.6
107
1789
H02AB06
ATC
prednisolone; systemic
1.1
7.6
3740
34528
8140/3-C53.0
ICD-O-3
Adenocarcinoma, NOS, of endocervix
8.0
7.6
16
20
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
3.0
7.6
41
138
XQ900
NOMESCO Finland
Photography of physically assaulted person
11.8
7.6
13
11
ZX040
NOMESCO Finland
Intracavity HDR radiotherapy
4.2
7.6
27
65
D11
ICPC
Diarrhoea
1.2
7.5
1079
9055
J01FA10
ATC
azithromycin; systemic
1.1
7.5
6103
57996
EMB10
NOMESCO Finland
Tonsillectomy
1.3
7.5
677
5399
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
2.7
7.5
46
168
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
2.1
7.5
76
358
N05BA04
ATC
oxazepam; oral
1.2
7.4
2082
18507
D10
ICPC
Vomiting
1.3
7.4
630
4986
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.2
7.4
774
6283
WX002
NOMESCO Finland
Sedation and analgesia
1.2
7.4
1149
9722
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.3
7.4
671
5359
Z30.8
ICD-10 Finland
Other contraceptive management
1.4
7.4
294
2065
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
1.3
7.3
751
6082
N86
ICD-10 Finland
Erosion and ectropion of cervix uteri
2.6
7.3
49
188
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
3.9
7.3
28
72
T810, N872
ICD-10 Finland
NA
+∞
7.3
7
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.3
7.2
671
5374
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
1.6
7.2
175
1104
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.2
7.2
957
7978
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
2.0
7.2
81
399
AA1AD
NOMESCO Finland
CT of head and brain
1.2
7.2
1115
9433
M01AH05
ATC
etoricoxib; oral
1.1
7.1
5304
50080
O04.6
ICD-10 Finland
Medical abortion, complete or unspecified, complicated by delayed or excessive haemorrhage
1.7
7.1
146
877
8113
FHL
Fractional scraping
1.5
7.1
261
1803
KMAK
NOMESCO Finland
NA
1.1
7.1
5619
53231
K05.30
ICD-10 Finland
Periodontitis complex
1.3
7.1
693
5581
B02AA02
ATC
tranexamic acid; systemic
1.2
7.1
1679
14729
TPH04
NOMESCO Finland
Cathetrisation of vein
1.2
7.1
1269
10878
R87.4
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal immunological findings
7.9
7.1
15
19
8323
FHL
Suturation
12.0
7.1
12
10
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.1
7.0
2399
21615
L03
ICPC
Low back symptom/complaint
1.2
7.0
2018
17966
LBE20
NOMESCO Finland
Laparoscopic bilateral salpingectomy
1.5
7.0
192
1246
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.2
7.0
955
7980
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.2
6.8
1459
12698
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
1.5
6.8
187
1215
SGC10
NOMESCO Finland
Covering pulpa of tooth
1.2
6.8
893
7430
F41.09
ICD-10 Finland
UNS Panic Syndrome
1.4
6.7
280
1985
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
3.8
6.7
26
68
F43.20
ICD-10 Finland
Adaptation disorder with short-term depression
1.7
6.7
137
827
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.3
6.6
654
5273
M01AE02
ATC
naproxen; oral, rectal
1.1
6.6
5455
51706
ZXC96
NOMESCO Finland
Robot assisted procedure
1.9
6.6
83
427
N93.8
ICD-10 Finland
Other specified abnormal uterine and vaginal bleeding
1.6
6.6
179
1160
Z00.0
ICD-10 Finland
General medical examination
1.2
6.5
1256
10831
C53.09
ICD-10 Finland
Malignant tumor of endocervix, unspecified histology
10.0
6.5
12
12
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
0.7
6.5
149
2238
LGA21
NOMESCO Finland
Laparoscopic sterilisation by constriction of Fallopian tubes
1.3
6.5
605
4847
YX9VG
NOMESCO Finland
Other MRI eamination with high intensity magnet for dose design of radiotherapy
6.8
6.5
15
22
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.2
6.5
1326
11496
8112
FHL
Scraping the cervix
4.5
6.4
21
47
ZX120
NOMESCO Finland
Intravenous
1.3
6.4
548
4341
KAY20
NOMESCO Finland
NA
0.6
6.4
81
1390
M25.5
ICD-10 Finland
Pain in joint
1.1
6.4
2531
22999
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
1.7
6.4
118
693
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
0.8
6.3
587
7198
C53.1
ICD-10 Finland
Malignant neoplasm: Exocervix
11.0
6.3
11
10
N06AX16
ATC
venlafaxine; oral
1.2
6.2
1338
11641
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.1
6.2
1915
17123
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
1.9
6.2
84
445
N06AB06
ATC
sertraline; oral
1.2
6.2
994
8440
K50.8
ICD-10 Finland
Other Crohn disease
1.7
6.2
114
668
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.2
6.1
1692
15004
A51.3
ICD-10 Finland
Secondary syphilis of skin and mucous membranes
5.3
6.1
17
32
N06AB10
ATC
escitalopram; oral
1.1
6.1
2083
18745
R03AC02
ATC
salbutamol; inhalant
1.1
6.1
5015
47445
8070/3-C53.0
ICD-O-3
Squamous cell carcinoma, NOS, of endocervix
12.5
6.1
10
8
N07BB01
ATC
disulfiram; oral
1.5
6.1
217
1498
N03AX16
ATC
pregabalin; oral
1.2
6.0
1603
14176
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.2
6.0
1552
13695
L02
ICPC
Back symptom/complaint
1.2
6.0
736
6084
SPAT1153
SPAT
Removal of sutures
1.1
6.0
1989
17862

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
6653
43816
2.15
307.65
2.6
1.9
—
—
—
0
0
2145
2253
11.34
307.65
2.3
1.4
—
—
—
0
0
1236
7022
1.84
80.50
1.4
1.4
—
—
—
0
0
91
223
4.10
33.27
1.5
2.1
6.5
3.9
ug/l
0.21
60
132
4010
34711
1.23
23.40
2.1
2.0
—
—
—
0
0
7433
68449
1.22
23.06
4.0
3.9
1883.0
1890.3
e6/l
0.00
72
722
7672
71018
1.21
21.96
4.2
3.9
—
—
—
0
0
8000
74819
1.20
18.63
4.0
3.7
9.7
9.9
mm/h
0.92
7560
70577
2690
22818
1.23
18.12
3.3
3.3
—
—
—
0
0
5611
51004
1.18
17.70
3.3
3.2
0.0
0.0
estimate
0.26
1096
10088
5673
51641
1.18
17.53
3.4
3.3
0.0
0.0
estimate
0.63
1110
10252
3637
31869
1.20
17.38
3.4
3.2
58.9
76.2
e6/l
1.57
2350
20652
5631
51253
1.18
17.35
4.5
4.4
0.0
0.0
estimate
0.16
1130
10397
10306
99088
1.26
17.10
10.4
9.9
3.9
3.9
mmol/l
0.16
10007
96289
7606
71067
1.18
16.90
7.0
6.6
71.2
72.5
u/l
2.29
7150
67223
10276
98792
1.26
16.89
10.3
9.8
139.5
139.6
mmol/l
1.87
10000
96238
3571
31467
1.19
15.64
6.1
5.7
—
—
—
0
0
1623
13234
1.26
15.43
2.4
2.3
1.0
1.2
e6/l
0.66
872
7016
5473
50032
1.17
15.14
6.0
5.6
0.0
0.0
e9/l
0.11
4846
44314
1527
12413
1.26
14.87
2.6
2.5
4.6
5.1
e6/l
0.80
781
6241
5449
49865
1.16
14.70
6.0
5.6
0.5
0.5
e9/l
0.16
4848
44274
10696
103598
1.27
14.62
11.1
10.2
18.8
18.4
mg/l
0.50
8279
79612
1623
13314
1.25
14.58
1.2
1.2
—
—
—
0
0
1976
16575
1.23
14.43
1.7
1.6
—
—
—
0
0
2627
22711
1.20
13.98
2.9
2.7
0.3
0.3
e6/l
0.48
1911
16556
5632
51919
1.15
13.20
6.2
5.8
0.2
0.2
e9/l
0.19
5121
46797
2625
22830
1.19
12.91
2.8
2.6
—
—
—
0
0
5108
46808
1.15
12.89
6.1
5.6
2.7
2.8
%
0.47
4778
43887
2850
24996
1.18
12.66
2.9
2.7
34.2
73.1
e6/l
2.74
2107
18584
5610
51831
1.15
12.45
6.0
5.6
2.0
2.0
e9/l
0.36
5105
46893
5123
47044
1.15
12.37
6.4
5.8
7.9
7.9
%
0.23
4827
44506
4930
45154
1.15
12.34
6.3
5.7
0.7
0.7
%
0.52
4605
42343
6151
57232
1.15
12.26
8.4
8.3
4.0
3.9
e9/l
0.31
5439
50670
11066
107981
1.27
11.72
9.1
8.5
23.8
23.9
u/l
0.18
10771
105076
5230
48352
1.14
10.95
5.9
5.4
56.3
56.5
%
0.99
4916
45710
2749
24283
1.17
10.93
6.2
6.2
—
—
—
0
0
10934
106653
1.25
10.84
11.4
10.7
66.3
66.1
umol/l
0.49
10929
106595
4819
44331
1.14
10.84
8.2
8.0
0.0
0.0
e9/l
4.91
3969
36477
5285
48984
1.14
10.47
6.1
5.6
29.9
29.8
%
0.56
4955
46156
4923
45447
1.14
10.33
5.3
5.2
9.3
9.5
umol/l
1.14
4615
42827
11223
109938
1.27
9.77
10.0
9.7
—
—
—
0
0
3883
35404
1.14
9.68
5.0
4.8
1.2
1.2
mmol/l
0.49
3559
32404
2500
22155
1.16
9.32
3.7
3.3
97.3
98.7
%
2.38
2424
21448
1360
11463
1.21
9.20
2.2
2.2
3994.9
6107.1
u/l
2.08
526
4776
3477
31559
1.14
9.18
2.1
1.9
—
—
—
0
0
4321
39770
1.13
9.16
5.7
5.4
1.2
1.2
mmol/l
0.90
3706
33658
3127
28296
1.14
8.53
2.5
2.5
—
—
—
0
0
6500
61501
1.12
8.28
2.8
2.8
—
—
—
0
0
2996
27079
1.14
8.28
3.7
3.5
0.0
0.0
estimate
0.30
1134
10296
585
4560
1.29
7.99
3.5
2.8
—
—
—
0
0
2379
21235
1.15
7.87
1.3
1.3
10.8
9.3
u/ml
0.53
965
9170
10191
99227
1.16
7.79
5.1
5.1
1.9
2.0
mu/l
0.04
9668
94434
2573
23162
1.14
7.45
2.0
1.9
—
—
—
0
0
378
2802
1.36
7.37
3.1
2.6
—
—
—
0
0
3600
33115
1.12
7.29
1.7
1.8
98.8
99.7
pmol/l
0.60
1968
17643
728
5903
1.25
7.20
1.4
1.3
—
—
—
0
0
2412
21673
1.14
7.15
3.5
3.5
1.0
1.0
kg/l
1.10
337
3397
575
4550
1.27
7.01
1.7
1.7
—
—
—
0
0
2633
23825
1.13
6.97
3.9
3.5
7.4
7.4
ph
0.47
469
4614
1798
15881
1.15
6.83
2.7
2.4
512.0
521.7
mosm/kgh2o
1.05
1528
13484
852
7074
1.22
6.74
1.3
1.2
—
—
—
0
0
7674
73657
1.11
6.72
2.9
2.7
34.0
33.7
u/l
0.15
7356
70503
1837
16274
1.15
6.68
2.5
2.4
100.5
100.1
ug/g
0.02
1419
12738
11788
116602
1.39
6.66
16.4
15.4
90.7
90.2
fl
40.22
11687
115644
11787
116591
1.39
6.65
16.4
15.4
30.2
30.0
pg
43.91
11688
115631
11788
116612
1.39
6.55
16.4
15.5
4.4
4.5
e12/l
14.16
11561
114455
11789
116642
1.38
6.36
16.5
15.5
6.8
6.7
e9/l
3.25
11564
114420
5298
49998
1.10
6.36
3.8
3.8
—
—
—
0
0
11776
116497
1.37
6.32
16.5
15.5
269.7
269.5
e9/l
0.13
11564
114472
11789
116654
1.38
6.24
16.5
15.5
133.1
133.0
g/l
0.89
11694
115692
9134
88639
1.12
6.13
4.4
4.4
14.3
14.3
pmol/l
0.18
8607
83613
3807
35394
1.11
6.09
4.5
4.2
36.8
36.7
g/l
0.45
3576
33028
2443
22170
1.12
6.07
1.3
1.3
39.0
28.6
iu/ml
0.37
781
6954
1200
10375
1.17
6.04
3.0
2.3
5.6
6.0
umol/l
0.53
992
8677
723
5977
1.22
6.00
2.6
2.0
—
—
—
0
0
782
6530
1.21
5.86
2.5
1.9
—
—
—
0
0
786
6576
1.21
5.78
2.5
1.9
—
—
—
0
0
1226
10659
1.16
5.75
1.5
1.5
—
—
—
0
0
3636
33807
1.10
5.74
3.3
3.0
30.2
29.3
u/l
0.25
3454
32363
9317
90615
1.11
5.70
13.3
12.4
13.5
13.5
%
0.53
9154
88972
1943
17461
1.13
5.64
2.4
2.3
8.9
8.5
e6/l
0.31
1666
15081
98
588
1.67
5.50
4.1
2.1
—
—
—
0
0
781
6563
1.20
5.49
2.2
1.9
—
—
—
0
0
1893
17016
1.13
5.47
1.4
1.4
549.8
571.9
titre
0.19
406
3431
614
5044
1.23
5.45
2.7
2.0
—
—
—
0
0
286
2141
1.34
5.35
1.9
1.9
—
—
—
0
0
3070
28399
1.11
5.29
2.4
2.4
53.1
56.8
u/l
6.66
2848
26386
94
565
1.67
5.26
1.1
1.2
—
—
—
0
0
1015
8765
1.17
5.20
2.2
2.8
45.2
36.9
u/ml
0.27
980
8488
986
8514
1.17
5.06
2.4
2.3
37.3
35.8
u/l
0.13
830
7278
764
6473
1.19
4.93
2.4
1.9
—
—
—
0
0
9652
94246
1.11
4.89
3.5
3.5
5.6
5.6
mmol/l
1.93
9064
88794
1248
11003
1.15
4.84
1.6
1.6
—
—
—
0
0
1171
10312
1.15
4.63
1.4
1.3
—
—
—
0
0
2462
22667
1.11
4.58
1.8
2.0
157.1
139.3
u/l
0.40
2346
21482
3202
29856
1.10
4.57
1.7
1.7
—
—
—
0
0
1568
14102
1.13
4.47
2.4
2.5
2.4
2.4
mmol/l
0.30
1348
12324
2628
24311
1.10
4.42
1.7
1.7
—
—
—
0
0
322
2521
1.28
4.42
1.5
1.6
—
—
—
0
0
350
2770
1.27
4.41
5.0
4.2
24.2
24.2
mmol/l
0.04
317
2469
575
4809
1.20
4.32
8.3
7.8
—
—
—
0
0
10
22
4.54
4.28
1.0
1.0
—
—
—
0
0
52
282
1.84
4.22
3.4
2.7
—
—
—
0
0
3125
29224
1.09
4.12
1.3
1.3
1.7
1.4
u/ml
0.47
943
8677
463
3822
1.22
4.01
1.3
1.4
23.6
24.4
u/l
0.25
365
3167
2627
24407
1.09
3.99
1.4
1.4
2.2
2.1
g/l
1.75
1612
15700
1419
12779
1.12
3.96
1.3
1.3
25.3
26.2
iu/l
0.53
1251
11167
117
798
1.47
3.88
2.5
2.0
43.9
46.1
%
0.23
16
135
1475
13333
1.12
3.86
2.8
2.8
195.9
289.4
ng/l
1.20
765
6901
97
639
1.52
3.81
2.9
2.6
765.2
885.9
e6/l
0.80
38
304
3132
29383
1.09
3.78
3.0
3.1
2.3
2.3
mmol/l
0.19
2821
26491
8714
85005
1.08
3.69
4.1
4.2
36.9
37.5
mmol/mol
10.73
8222
80600
852
7461
1.15
3.69
2.6
2.5
10.5
10.4
g/l
0.54
785
6837
72
447
1.61
3.67
2.8
2.7
42.1
44.5
%
0.23
16
175
727
6296
1.16
3.66
2.5
2.6
—
—
—
0
0
10126
99457
1.10
3.57
3.7
3.7
2.9
2.9
mmol/l
0.45
9594
94252
1277
11503
1.12
3.56
1.8
1.8
—
—
—
0
0
730
6356
1.16
3.44
3.4
3.3
—
—
—
0
0
268
2123
1.27
3.44
3.1
3.4
231.9
359.3
u/ml
0.39
226
1803
1899
17504
1.10
3.40
1.5
1.5
21.5
21.1
nmol/l
0.47
1677
15537
1134
10183
1.12
3.34
1.3
1.4
—
—
—
0
0
2924
27485
1.08
3.31
2.5
2.5
25.4
56.4
ng/l
0.58
1176
11702
436
3652
1.20
3.31
1.3
1.3
39.7
33.0
u/ml
0.34
41
254
107
744
1.44
3.27
2.1
2.3
—
—
—
0
0
584
5034
1.17
3.17
1.1
1.1
35.8
8.7
u/ml
—
9
72
96
661
1.45
3.11
1.5
1.5
1.4
1.3
promille
0.32
74
495
19
79
2.40
3.11
7.7
10.2
4.5
5.0
mmol/l
0.40
19
79
750
6606
1.14
3.04
1.4
1.3
207.7
233.7
miu/ml
1.42
385
3406
398
3339
1.20
3.00
1.2
1.2
—
—
—
0
0
43
721
0.59
3.00
1.3
1.5
—
—
—
0
0
437
3700
1.19
2.98
2.5
1.9
0.2
0.2
g/l
1.14
408
3525
849
7552
1.13
2.96
6.8
6.3
104.8
104.9
mmol/l
0.31
833
7411
5284
50887
1.06
2.91
4.0
3.8
6.2
6.3
mmol/l
1.46
4796
45744
10022
98577
1.09
2.90
3.5
3.5
4.9
4.9
mmol/l
0.30
9581
94059
447
3805
1.18
2.87
2.5
1.9
1.1
1.2
g/l
2.17
420
3635
9596
94241
1.08
2.85
3.1
3.2
1.2
1.2
mmol/l
0.05
9107
89595
9972
98084
1.08
2.83
3.4
3.5
1.6
1.6
mmol/l
0.26
9503
93435
297
2443
1.22
2.78
3.0
2.5
—
—
—
0
0
66
433
1.52
2.75
2.0
2.3
131.9
171.3
umol/l
0.64
43
207
690
6091
1.14
2.73
1.3
1.4
—
—
—
0
0
317
2631
1.21
2.72
2.2
1.9
1.4
1.4
g/l
0.52
273
2273
103
739
1.39
2.71
3.3
2.7
—
—
—
0
0
649
5712
1.14
2.69
1.7
1.8
1.3
1.3
g/l
0.52
600
5289
584
5107
1.15
2.66
4.0
3.6
2.0
1.8
mmol/l
0.70
477
4142
783
6994
1.13
2.58
12.7
12.7
1.1
1.1
inr
0.08
114
1199
489
4233
1.16
2.58
1.2
1.2
—
—
—
0
0
4517
43422
1.06
2.54
2.3
2.3
75.9
2089.2
nmol/l
0.50
4190
40715
1334
12269
1.10
2.53
3.2
3.0
0.8
0.8
mmol/l
0.96
1247
11494
854
7679
1.12
2.52
2.4
2.3
4.2
4.1
e9/l
0.41
708
6478
66
444
1.49
2.48
2.0
2.0
—
—
—
0
0
2501
23608
1.07
2.48
2.1
2.1
2.7
2.7
mg/l
0.54
2144
20428
241
1969
1.23
2.46
3.9
2.9
1.4
1.3
mg/l
0.64
229
1846
585
5150
1.14
2.45
4.1
3.6
5.9
5.8
kpa
0.70
572
4984
421
3626
1.16
2.40
2.1
2.0
—
—
—
0
0
609
5386
1.14
2.38
1.3
1.3
1.6
1.0
u/ml
0.41
52
433
2521
23836
1.07
2.38
1.7
1.7
0.9
0.9
mg/l
0.53
1860
17716
337
2855
1.18
2.36
9.1
8.8
24.2
24.1
mmol/l
0.08
315
2693
5994
58184
1.06
2.32
2.9
3.0
71.8
68.3
ug/l
1.06
5673
55419
1358
12551
1.09
2.32
1.7
1.7
1178.8
1186.5
nmol/l
0.12
1095
9920
891
8071
1.11
2.32
2.3
2.3
18.8
22.4
au/ml
0.72
57
652
434
3758
1.16
2.32
6.1
6.1
24.6
24.5
mmol/l
0.08
429
3729
386
3315
1.17
2.30
1.4
1.3
12.1
8.6
u/ml
0.40
70
542
380
3260
1.17
2.29
1.4
1.3
15.6
5.5
u/ml
1.16
54
344
251
2078
1.21
2.27
2.3
2.0
3.6
3.7
g/l
0.02
189
1520
66
453
1.46
2.27
3.9
3.1
—
—
—
0
0
523
4597
1.14
2.27
1.7
1.8
—
—
—
0
0
40
629
0.63
2.23
1.1
1.2
—
—
—
0
0
1170
10766
1.09
2.22
1.5
1.4
—
—
—
0
0
433
3768
1.15
2.18
2.9
2.8
—
—
—
0
0
117
892
1.31
2.16
1.6
1.4
57.2
66.8
mmol/l
1.84
99
697
200
1630
1.23
2.14
1.8
1.9
39.0
38.9
g/l
0.10
179
1445
171
1371
1.25
2.13
3.2
3.1
37.3
38.3
mg/l
0.07
141
1099
1110
10213
1.09
2.12
1.2
1.2
—
—
—
0
0
54
364
1.48
2.06
2.4
2.0
—
—
—
0
0
44
284
1.55
2.05
1.8
1.6
—
—
—
0
0
170
1370
1.24
2.03
3.2
3.1
29.0
35.0
mg/l
0.57
140
1100
1173
10840
1.09
2.03
2.0
2.1
29.4
29.1
s
0.60
1141
10477
622
5570
1.12
2.03
7.1
7.2
96.3
96.4
%
0.05
595
5339
2894
27616
1.06
2.02
5.0
5.1
1.1
1.1
inr
0.04
954
9290
54
367
1.47
1.99
2.4
2.0
7.7
8.6
%
0.28
54
361
37
231
1.60
1.99
4.5
5.2
—
—
—
0
0
156
1249
1.25
1.99
5.2
5.4
383.0
376.1
umol/l
0.23
140
1080
174
1414
1.23
1.94
2.2
1.7
32.6
35.2
iu/ml
0.11
17
77
1884
17761
1.07
1.94
3.9
3.6
—
—
—
0
0
588
5267
1.12
1.93
6.9
6.4
1.2
1.2
mmol/l
0.82
564
5089
1294
12049
1.08
1.88
2.4
2.2
2.4
2.5
g/l
2.46
1179
11207
713
6465
1.11
1.88
6.7
6.7
13.4
13.7
kpa
0.63
675
6172
713
6467
1.11
1.87
6.8
6.7
5.1
5.0
kpa
0.62
678
6179
48
324
1.48
1.85
24.0
24.8
112.9
112.5
ug/l
0.01
40
262
818
7473
1.10
1.85
1.3
1.3
30.6
39.6
au/ml
0.84
24
303
248
2097
1.18
1.85
1.2
1.3
—
—
—
0
0
734
6673
1.10
1.84
3.3
3.6
18.1
23.3
ug/l
0.20
546
4799
3138
30091
1.05
1.83
2.9
2.8
—
—
—
0
0
713
6474
1.11
1.83
6.7
6.7
0.9
0.8
mmol/l
0.12
536
4904
13
59
2.20
1.83
1.0
1.6
—
—
—
0
0
341
2962
1.15
1.82
1.3
1.3
—
—
—
0
0
151
1219
1.24
1.82
4.2
3.5
—
—
—
0
0
467
4150
1.13
1.78
3.3
3.0
4.5
4.7
kpa
0.92
453
4006
54
378
1.43
1.75
1.7
1.6
172.9
136.7
au/ml
—
10
45
10
41
2.43
1.74
1.2
1.2
—
—
—
0
0
42
281
1.49
1.71
1.1
1.1
—
—
—
0
0
305
2644
1.15
1.69
2.4
2.1
10.0
10.1
mg/l
0.14
291
2489
227
1923
1.18
1.69
2.3
2.0
10.3
10.1
g/l
0.25
196
1653
380
3346
1.14
1.69
1.4
1.5
6.4
9.5
u/ml
—
8
87
337
2944
1.15
1.68
1.3
1.3
46.5
39.7
u/ml
0.35
40
314
546
4916
1.11
1.67
9.2
7.0
7.9
7.2
mmol/l
1.77
522
4734
108
848
1.27
1.67
1.3
1.3
21.0
59.5
u/ml
—
5
43
13
62
2.09
1.64
1.0
1.6
—
—
—
0
0
588
5322
1.11
1.64
7.5
7.4
119.1
120.8
g/l
1.32
571
5117
161
1328
1.21
1.61
3.3
3.1
1.4
1.9
ratio
—
10
145
278
2404
1.16
1.61
1.3
1.4
331.4
308.1
ug/g
1.03
163
1228
348
3058
1.14
1.61
1.1
1.1
—
—
—
0
0
45
311
1.45
1.59
1.2
1.3
—
—
—
0
0
755
6934
1.09
1.57
2.4
2.2
0.2
0.2
g/l
1.76
708
6548
457
4092
1.12
1.57
1.9
2.0
6.3
5.5
ug/l
0.18
407
3567
256
2206
1.16
1.57
1.3
1.2
288.2
258.8
u/ml
1.01
180
1491
1531
16146
0.94
1.57
1.3
1.3
—
—
—
0
0
202
1709
1.18
1.55
1.4
1.5
—
—
—
0
0
2440
23344
1.05
1.55
1.6
1.6
1.4
1.3
mmol/l
0.25
2123
20415
82
629
1.30
1.54
3.2
2.5
57.0
56.2
%
0.11
52
398
346
3059
1.13
1.48
8.4
8.6
—
—
—
0
0
243
2098
1.16
1.47
1.4
1.4
10.1
13.2
iu/ml
—
9
51
32
210
1.52
1.46
1.7
1.7
—
—
—
0
0
66
497
1.33
1.43
2.2
2.5
10.4
11.1
%
0.79
66
497
6
22
2.72
1.43
1.0
1.1
178.5
242.4
nmol/l
—
6
22
21
125
1.68
1.42
1.2
1.2
—
—
—
0
0
4117
42217
0.96
1.41
2.2
2.2
—
—
—
0
0
73
561
1.30
1.38
3.2
2.5
0.2
0.2
e9/l
0.21
73
552
647
5942
1.09
1.38
1.1
1.1
—
—
—
0
0
10132
100226
1.05
1.38
12.0
11.0
39.6
39.5
%
1.55
8412
82299
61
458
1.33
1.36
2.8
3.1
0.8
0.8
nmol/l
0.41
45
333
0
37
0.00
1.34
0.0
1.3
—
—
—
0
0
142
1185
1.20
1.32
3.3
3.0
33.2
33.0
umol/l
0.02
127
1025
88
698
1.26
1.32
1.6
1.3
—
—
—
0
0
125
1031
1.21
1.31
1.2
1.2
—
—
—
0
0
0
41
0.00
1.31
0.0
1.0
—
0.0
—
0
30
126
1041
1.21
1.30
2.9
2.6
1.2
1.4
%
0.42
91
811
292
2582
1.13
1.29
1.2
1.3
—
—
—
0
0
41
292
1.40
1.28
3.1
4.1
4122.2
3208.4
mg/l
0.08
32
212
844
7865
1.08
1.28
1.2
1.2
—
—
—
0
0
10
192
0.52
1.27
1.2
1.2
—
—
—
0
0
790
7345
1.08
1.27
3.1
3.4
—
—
—
0
0
8
35
2.28
1.26
1.0
1.0
—
—
—
0
0
63
482
1.31
1.26
2.0
1.8
8.8
9.6
mg/l
0.48
51
390
28
187
1.50
1.22
1.1
1.1
—
—
—
0
0
214
2443
0.87
1.22
1.6
1.6
7.6
7.5
mmol/l
0.03
134
1500
1648
17196
0.95
1.20
2.0
2.0
—
—
—
0
0
1244
11774
1.06
1.19
1.2
1.2
162.3
152.2
iu/ml
0.32
481
4715
1138
10747
1.06
1.18
2.6
2.3
24.6
23.7
%
1.40
989
9312
153
1307
1.17
1.13
1.5
1.6
—
—
—
0
0
355
3908
0.90
1.12
1.2
1.2
—
—
—
0
0
716
6671
1.08
1.12
2.4
2.5
1.7
1.7
%
0.04
643
5952
97
796
1.22
1.11
2.3
2.0
10.3
13.0
%
1.53
40
423
39
284
1.37
1.10
1.0
1.1
—
—
—
0
0
35
480
0.73
1.10
1.6
1.6
4.6
5.8
mmol/24h
—
5
42
1414
13471
1.05
1.09
2.4
2.2
14.9
14.4
umol/l
1.94
1306
12534
457
4187
1.09
1.09
1.4
1.4
81.2
97.8
pmol/l
0.65
451
4082
122
1027
1.19
1.08
3.5
3.2
—
—
—
0
0
1001
10554
0.94
1.07
1.6
1.7
—
—
—
0
0
15
89
1.68
1.06
1.0
1.1
1.6
1.5
umol/24h
0.13
15
89
286
2565
1.12
1.05
3.2
2.8
0.2
0.3
g/l
1.53
109
1009
260
2320
1.12
1.04
1.3
1.4
—
—
—
0
0
736
6886
1.07
1.04
4.0
3.8
0.7
0.6
%
0.13
143
1207
947
8934
1.06
1.04
6.3
4.9
1.0
1.0
mmol/l
0.07
891
8402
153
1321
1.16
1.01
1.1
1.1
—
—
—
0
0
1876
18038
1.04
1.00
1.4
1.4
—
—
—
0
0
1362
13001
1.05
0.99
1.2
1.2
—
—
—
0
0
493
4558
1.08
0.97
2.4
2.5
70.4
72.4
e9/l
0.50
369
3290
1512
14479
1.05
0.97
2.5
2.4
616.8
622.8
ng/l
0.03
1233
11725
16
100
1.60
0.95
1.6
2.2
0.6
0.9
u/field
0.43
16
100
203
1797
1.13
0.95
2.5
2.6
—
—
—
0
0
60
477
1.26
0.95
2.4
2.4
258.4
154.6
au/ml
—
5
81
281
2535
1.11
0.95
3.3
3.0
0.6
0.7
%
0.63
267
2428
976
9249
1.06
0.94
3.3
3.4
4.6
4.5
pmol/l
0.35
867
8370
384
3521
1.09
0.93
4.0
4.6
—
—
—
0
0
736
6918
1.07
0.93
1.1
1.1
202.7
197.5
titre
0.02
21
166
108
916
1.18
0.92
1.2
1.2
—
—
—
0
0
197
1746
1.13
0.92
1.4
1.4
—
—
—
0
0
2665
25858
1.04
0.91
4.0
3.9
—
—
—
0
0
367
3365
1.09
0.90
3.3
3.2
128.7
129.6
g/l
0.37
361
3279
66
535
1.23
0.90
2.4
2.4
—
—
—
0
0
25
348
0.72
0.90
1.3
1.5
—
—
—
0
0
140
1216
1.15
0.89
1.1
1.1
1.4
1.5
g/l
0.68
131
1105
3661
35734
1.03
0.88
1.7
1.7
—
—
—
0
0
20
135
1.48
0.88
1.1
1.2
—
—
—
0
0
918
8708
1.06
0.87
1.2
1.3
211.3
175.6
u/ml
0.39
847
8087
185
1640
1.13
0.87
1.4
1.3
49.6
51.4
u/ml
0.03
13
108
89
747
1.19
0.87
1.1
1.2
20.0
97.1
titre
—
5
14
116
996
1.16
0.86
2.8
2.3
1.4
1.3
e9/l
0.11
67
572
89
748
1.19
0.86
1.1
1.2
338.8
182.9
titre
0.66
16
144
66
801
0.82
0.85
6.2
6.5
—
—
—
0
0
42
326
1.29
0.83
1.2
1.5
—
—
—
0
0
10
57
1.75
0.83
5.1
3.6
—
—
—
0
0
74
614
1.20
0.82
1.3
1.5
23901.9
50400.2
e6/l
0.53
50
422
240
2170
1.11
0.81
1.3
1.3
134.6
109.3
u/ml
0.64
53
527
59
479
1.23
0.81
2.4
2.5
—
—
—
0
0
6
32
1.87
0.81
1.2
1.0
—
—
—
0
0
504
4706
1.07
0.81
2.4
2.3
67.0
67.2
g/l
0.27
459
4354
56
453
1.23
0.80
1.1
1.1
1.7
2.0
u/ml
0.08
35
251
28
206
1.36
0.80
2.8
2.1
—
—
—
0
0
582
5465
1.07
0.80
3.7
3.4
77.9
75.9
ng/l
0.21
533
4855
33
430
0.77
0.79
2.5
2.1
1.5
1.3
ug/l
0.13
33
411
762
7215
1.06
0.79
4.2
4.1
0.1
0.2
%
0.94
177
1531
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
254
2308
1.10
0.79
1.3
1.3
19.3
18.8
u/ml
—
5
49
444
4133
1.07
0.78
2.3
2.4
141.6
108.7
ng/l
0.89
391
3687
33
250
1.32
0.78
1.0
1.0
—
—
—
0
0
8
48
1.66
0.78
1.5
1.3
294.7
519.4
nmol/l
—
8
48
0
26
0.00
0.78
0.0
1.0
—
0.1
—
0
20
20
139
1.44
0.78
1.1
1.2
—
—
—
0
0
5
96
0.52
0.78
1.2
1.5
—
14.4
—
0
11
60
726
0.82
0.78
14.4
16.9
1447.4
3828.8
nmol/l
0.82
60
694
57
693
0.82
0.77
11.7
12.0
834.5
845.3
nmol/l
0.06
57
670
504
4716
1.07
0.77
1.6
1.7
—
—
—
0
0
12
74
1.62
0.77
14.3
7.4
—
—
—
0
0
2281
22144
1.03
0.77
3.4
3.1
7.4
8.1
mmol/l
0.47
1980
19134
95
813
1.17
0.76
1.6
1.7
—
—
—
0
0
26
348
0.74
0.76
1.1
1.2
—
—
—
0
0
789
7497
1.05
0.74
4.2
4.0
0.7
0.9
%
1.01
186
1643
10
160
0.62
0.74
5.6
5.3
—
—
—
0
0
7
38
1.84
0.73
1.1
1.1
—
—
—
0
0
2224
21603
1.03
0.73
2.2
2.0
1795.6
2599.5
umol/l
0.89
1991
19298
730
6925
1.06
0.73
4.2
4.1
0.1
0.2
%
0.21
149
1311
329
3041
1.08
0.72
7.6
7.1
—
—
—
0
0
5
26
1.92
0.70
1.0
1.3
—
—
—
0
0
91
784
1.16
0.69
1.3
1.2
28.6
30.8
u/l
0.06
81
689
9
58
1.55
0.69
1.0
1.2
—
—
—
0
0
98
1122
0.87
0.68
2.3
2.4
1.4
1.4
mmol/l
0.07
98
1096
186
1681
1.11
0.68
1.1
1.1
—
—
—
0
0
83
712
1.16
0.67
3.2
2.6
—
—
—
0
0
134
1192
1.12
0.65
1.2
1.3
—
—
—
0
0
2104
20469
1.03
0.64
2.8
2.8
—
—
—
0
0
158
1421
1.11
0.64
1.4
1.4
—
—
—
0
0
84
725
1.16
0.64
1.5
1.7
279.9
281.4
mosm/kgh2o
0.24
66
580
281
2597
1.08
0.64
1.1
1.1
—
—
—
0
0
181
1640
1.10
0.64
1.7
1.7
6506.3
8226.9
e6/l
0.75
133
1217
86
987
0.87
0.64
1.2
1.2
0.1
0.9
u/ml
2.33
28
371
125
1398
0.89
0.63
4.2
4.3
110.9
106.2
u/ml
0.03
42
446
27
207
1.30
0.62
1.6
1.5
—
—
—
0
0
47
566
0.83
0.62
1.9
2.0
—
—
—
0
0
45
544
0.82
0.62
1.1
1.2
—
—
—
0
0
112
990
1.13
0.62
1.0
1.0
—
—
—
0
0
91
1037
0.87
0.62
2.4
2.5
6.8
7.1
mmol/l
0.85
91
1016
390
3656
1.07
0.61
2.3
2.1
36.0
10.5
iu/l
0.38
173
1525
6
105
0.57
0.61
3.2
3.1
589.0
3189.2
u/l
—
6
97
280
2595
1.08
0.61
1.1
1.1
—
—
—
0
0
31
244
1.27
0.60
1.2
1.2
—
—
—
0
0
242
2232
1.08
0.59
3.8
4.4
—
—
—
0
0
61
518
1.18
0.58
3.0
2.9
9.0
8.0
mg/l
0.35
48
405
143
1288
1.11
0.58
2.9
2.4
9.1
8.8
kpa
0.55
132
1207
25
192
1.30
0.58
1.8
1.8
—
—
—
0
0
8
53
1.51
0.58
1.8
1.4
—
—
—
0
0
120
1072
1.12
0.57
1.4
1.4
—
—
—
0
0
158
1433
1.10
0.57
2.2
2.3
—
—
—
0
0
194
1777
1.09
0.57
1.1
1.1
—
—
—
0
0
36
291
1.24
0.57
2.5
2.8
7.4
7.4
ph
0.25
13
75
34
418
0.81
0.56
1.1
1.1
—
—
—
0
0
166
1814
0.91
0.56
3.4
3.2
25.1
23.0
mg/l
0.21
80
1095
5
87
0.57
0.56
1.0
1.4
3.2
3.8
%
—
5
78
16
115
1.39
0.56
1.4
1.1
—
—
—
0
0
127
1141
1.11
0.55
1.3
1.4
—
—
—
0
0
93
820
1.13
0.55
1.1
1.1
—
—
—
0
0
140
1540
0.91
0.54
3.7
2.9
0.9
0.9
nmol/l
0.12
121
1304
22
284
0.77
0.54
1.0
1.1
0.1
0.9
u/ml
1.49
14
201
77
671
1.15
0.54
1.1
1.1
—
—
—
0
0
8
124
0.64
0.54
2.5
2.0
1.2
1.2
mmol/l
—
8
115
207
1907
1.08
0.54
1.1
1.1
—
—
—
0
0
397
4190
0.94
0.54
1.1
1.1
3.4
4.9
u/ml
0.81
77
671
6
38
1.58
0.54
1.0
1.0
—
—
—
0
0
6
38
1.58
0.54
1.0
1.0
—
—
—
0
0
6
38
1.58
0.54
1.0
1.0
—
—
—
0
0
6
38
1.58
0.54
1.0
1.0
—
—
—
0
0
111
992
1.12
0.53
1.9
2.0
177.8
1495.7
u/ml
0.63
100
847
703
7309
0.96
0.53
1.4
1.4
—
—
—
0
0
6
39
1.54
0.53
1.0
1.0
—
—
—
0
0
224
2407
0.93
0.52
1.1
1.1
2.5
2.8
u/ml
0.25
129
1320
141
1544
0.91
0.51
3.7
2.7
—
—
—
0
0
6
40
1.50
0.51
1.0
1.4
83.7
68.9
%
—
6
35
703
7298
0.96
0.51
1.4
1.4
—
—
—
0
0
19
247
0.77
0.50
1.2
1.4
206.1
107.9
nmol/l
1.05
14
194
30
242
1.24
0.50
2.4
2.0
—
—
—
0
0
375
3543
1.06
0.49
6.0
6.3
24.3
24.4
mmol/l
0.10
352
3271
21
162
1.29
0.49
1.4
1.5
—
—
—
0
0
18
136
1.32
0.48
1.2
1.3
—
—
—
0
0
160
1468
1.09
0.48
2.8
2.6
24.8
24.3
mmol/l
0.95
140
1298
185
1992
0.93
0.47
1.1
1.1
116.5
120.5
%
1.05
167
1815
299
2811
1.06
0.47
1.3
1.3
107.6
145.6
titre
0.36
29
272
723
7486
0.96
0.47
1.5
1.5
—
—
—
0
0
7
48
1.46
0.46
2.1
2.0
—
—
—
0
0
45
382
1.18
0.46
1.5
1.8
—
—
—
0
0
76
672
1.13
0.46
1.1
1.1
8.5
11.1
u/ml
0.25
13
114
382
4010
0.95
0.46
1.2
1.2
—
—
—
0
0
7
49
1.43
0.45
1.0
1.0
—
—
—
0
0
23
182
1.26
0.45
1.7
1.7
—
—
—
0
0
23
182
1.26
0.45
1.5
1.1
—
—
—
0
0
125
1138
1.10
0.45
1.3
1.4
2.7
3.0
g/l
1.66
84
808
173
1863
0.93
0.45
1.4
1.3
1.4
1.4
nmol/l
0.00
149
1541
125
1139
1.10
0.45
1.3
1.4
0.4
0.4
g/l
0.22
84
814
7
50
1.40
0.45
1.0
1.3
256.7
143.3
ug/g
—
7
40
46
534
0.86
0.44
1.3
1.5
123.9
131.7
nmol/l
0.71
46
534
125
1140
1.10
0.44
1.3
1.4
7.1
6.6
g/l
0.63
83
811
291
2742
1.06
0.44
1.2
1.3
523.3
442.9
mg/l
0.62
278
2624
196
2097
0.93
0.44
1.2
1.2
—
—
—
0
0
178
1910
0.93
0.43
2.3
2.0
3.5
1.9
ug/l
0.61
153
1700
122
1330
0.91
0.43
2.7
2.5
67.5
75.5
ug/min
0.12
79
843
105
951
1.10
0.43
1.0
1.0
0.5
0.3
u/ml
—
9
128
5
31
1.61
0.43
3.4
2.1
—
—
—
0
0
19
148
1.28
0.42
1.0
1.4
—
134.6
—
0
17
11
78
1.41
0.42
1.4
1.9
—
—
—
0
0
8
56
1.43
0.42
1.0
1.1
—
—
—
0
0
201
1876
1.07
0.42
2.2
2.1
492.3
420.2
ug/l
0.13
176
1651
28
230
1.22
0.41
2.6
1.5
—
—
—
0
0
53
604
0.88
0.41
1.9
1.6
1.6
11.6
nmol/l
0.59
42
492
216
2296
0.94
0.41
1.5
1.5
7.0
6.6
mmol/l
0.82
155
1655
229
2149
1.06
0.41
1.2
1.2
—
—
—
0
0
114
1041
1.09
0.40
1.0
1.1
0.3
1.3
u/ml
1.53
28
269
1754
17855
0.98
0.40
1.6
1.6
56040046.1
36097804.0
pmol/l
0.61
1515
15569
92
832
1.10
0.40
1.2
1.2
—
—
—
0
0
258
2433
1.06
0.40
1.2
1.3
87.6
20.6
e6/l
0.73
198
1878
8
61
1.31
0.39
1.4
1.6
322.3
305.7
umol/24h
—
8
61
1781
18117
0.98
0.39
3.5
3.2
472.1
491.6
mg/l
0.06
1101
10893
5
35
1.43
0.39
1.2
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
2.0
—
—
—
0
0
0
19
0.00
0.39
0.0
2.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.9
—
—
—
0
0
29
345
0.84
0.39
1.4
1.4
24946.0
53834.6
e6/l
0.58
20
193
415
3967
1.05
0.38
2.5
2.4
0.3
0.3
e6/l
0.02
394
3788
110
1006
1.09
0.38
1.1
1.1
—
—
—
0
0
258
2436
1.06
0.38
1.2
1.3
15369.1
1400.1
e6/l
0.47
204
1975
90
815
1.10
0.38
1.4
1.6
5.8
5.9
mmol/l
0.19
70
654
249
2349
1.06
0.38
1.2
1.1
—
—
—
0
0
126
1160
1.08
0.38
1.2
1.4
—
—
—
0
0
137
1266
1.08
0.38
1.5
1.4
—
—
—
0
0
229
2156
1.06
0.38
4.3
4.8
1.2
1.2
mmol/l
0.23
206
1898
139
1495
0.93
0.38
1.4
1.5
9.2
10.9
mmol/l
1.48
20
187
36
419
0.86
0.38
2.5
2.3
575.6
605.4
ml
0.26
30
336
54
608
0.89
0.36
1.7
1.8
4.2
2.2
u/field
0.74
31
314
85
772
1.10
0.35
1.4
1.5
—
—
—
0
0
1065
10885
0.97
0.35
1.4
1.4
—
—
—
0
0
211
2229
0.94
0.35
3.3
2.8
24.7
24.7
mmol/l
0.09
201
2078
5
80
0.62
0.35
5.2
1.9
14.4
14.7
ml/dl
—
5
73
15
117
1.28
0.34
2.3
2.3
—
—
—
0
0
67
602
1.11
0.34
1.3
1.3
—
—
—
0
0
16
126
1.27
0.34
1.6
2.0
—
—
—
0
0
47
413
1.14
0.34
2.1
2.0
53.9
20.1
ug/l
0.64
47
406
179
1680
1.06
0.34
3.5
4.0
3.7
3.8
mmol/l
0.10
169
1577
146
1361
1.07
0.34
5.2
6.2
11.1
11.1
mmol/l
0.01
132
1223
146
1362
1.07
0.33
5.2
6.2
105.9
105.6
mmol/l
0.35
132
1224
40
456
0.87
0.33
1.6
1.7
—
—
—
0
0
99
910
1.09
0.33
1.1
1.2
—
—
—
0
0
116
1247
0.93
0.33
1.7
1.6
—
—
—
0
0
35
302
1.16
0.33
3.6
2.7
147.2
85.5
ng/l
0.45
17
153
113
1046
1.08
0.32
3.0
2.4
—
—
—
0
0
171
1607
1.06
0.32
1.3
1.3
—
—
—
0
0
497
5128
0.97
0.32
1.1
1.1
—
—
—
0
0
11
83
1.32
0.31
1.1
1.0
—
—
—
0
0
41
360
1.14
0.31
1.0
1.1
—
—
—
0
0
969
9450
1.03
0.31
3.6
3.3
—
—
—
0
0
153
1623
0.94
0.31
1.1
1.1
104.1
6410.6
iu/ml
0.63
42
420
11
142
0.77
0.31
1.1
1.4
—
—
—
0
0
7
99
0.71
0.30
1.0
1.2
—
—
—
0
0
97
896
1.08
0.30
1.7
2.0
—
0.8
—
0
6
15
185
0.81
0.30
1.7
1.3
29.2
44.2
%
—
10
120
326
3382
0.96
0.29
1.2
1.3
—
—
—
0
0
100
927
1.08
0.29
1.0
1.1
7.3
8.8
iu/ml
0.41
34
284
166
1568
1.06
0.28
2.3
1.9
131.1
130.7
g/l
0.07
119
1175
171
1800
0.95
0.28
1.3
1.4
29.5
31.8
nmol/l
0.60
162
1649
21
176
1.19
0.28
1.0
1.1
0.6
0.6
umol/24h
0.14
16
88
11
85
1.29
0.27
2.6
2.1
—
—
—
0
0
12
150
0.80
0.27
1.2
1.1
—
—
—
0
0
46
510
0.90
0.27
1.2
1.1
—
—
—
0
0
49
541
0.90
0.27
1.0
1.0
—
—
—
0
0
91
845
1.08
0.26
1.1
1.2
—
—
—
0
0
62
674
0.92
0.25
1.4
1.4
64.8
64.9
umol/l
—
5
54
54
591
0.91
0.25
1.0
1.1
—
—
—
0
0
81
750
1.08
0.25
3.1
2.4
0.2
0.2
e9/l
0.05
71
628
66
607
1.09
0.24
3.3
2.7
1078.0
847.7
u/ml
0.25
66
602
15
180
0.83
0.24
2.7
6.3
—
—
—
0
0
39
349
1.12
0.24
1.2
1.2
22.3
18.5
%
—
10
62
82
762
1.07
0.24
3.0
2.4
569.6
516.6
e6/l
0.61
71
624
30
264
1.13
0.24
1.1
1.5
—
—
—
0
0
799
7813
1.02
0.23
1.5
1.6
287.5
311.6
mu/l
1.10
722
6921
47
515
0.91
0.23
2.9
2.9
—
—
—
0
0
105
986
1.06
0.23
1.3
1.2
—
—
—
0
0
902
8834
1.02
0.23
1.4
1.4
—
—
—
0
0
75
696
1.08
0.23
3.7
2.9
—
—
—
0
0
5
39
1.28
0.23
1.0
1.0
—
—
—
0
0
5
39
1.28
0.23
1.2
1.2
—
—
—
0
0
1873
18917
0.99
0.22
4.0
3.9
12.0
9.7
mg/mmol
0.72
1147
11670
41
370
1.11
0.22
1.0
1.1
—
—
—
0
0
61
562
1.08
0.22
3.1
2.6
118.7
104.2
nmol/l
0.15
61
550
7
92
0.76
0.22
14.3
12.4
—
—
—
0
0
5
40
1.25
0.22
1.0
1.1
—
—
—
0
0
26
294
0.88
0.22
1.0
1.0
267.6
336.9
ng/l
1.21
18
223
15
125
1.20
0.22
2.6
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
—
—
0
0
5
42
1.19
0.21
1.0
1.1
—
—
—
0
0
18
209
0.86
0.21
1.1
1.1
—
—
—
0
0
66
708
0.93
0.21
1.1
1.1
1446.1
1497.5
miu/ml
0.14
66
708
70
749
0.93
0.21
1.3
1.4
5.1
7.1
ug/l
1.91
65
672
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
6.8
—
0
6
424
4343
0.97
0.21
1.3
1.3
3.6
3.1
ug/l
0.28
391
3991
33
366
0.90
0.21
1.7
1.5
3.8
4.9
%
0.35
11
79
14
166
0.84
0.21
2.8
2.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
0.4
—
0
13
0
13
0.00
0.21
0.0
1.1
—
0.1
—
0
5
12
98
1.22
0.21
1.0
1.1
0.1
22.5
u/ml
—
6
40
192
1842
1.04
0.20
3.1
2.4
—
—
—
0
0
39
354
1.10
0.20
1.9
2.1
253.2
181.3
e6/l
0.38
22
187
238
2295
1.04
0.20
1.2
1.3
—
—
—
0
0
9
115
0.78
0.20
1.0
1.0
0.2
0.5
u/ml
—
9
104
14
165
0.85
0.19
1.7
2.6
—
—
—
0
0
128
1218
1.05
0.19
1.1
1.2
33.0
36.8
mg/l
0.65
100
1022
42
384
1.09
0.19
1.2
1.2
6.1
6.1
mmol/l
0.01
37
357
17
196
0.87
0.19
1.5
1.6
—
—
—
0
0
12
143
0.84
0.19
1.3
1.1
—
—
—
0
0
28
311
0.90
0.19
3.0
2.9
30.2
27.8
umol/l
0.96
21
230
352
3604
0.97
0.18
3.2
2.8
7.4
7.4
ph
0.42
54
511
10
121
0.82
0.18
3.0
2.2
5.4
6.5
mmol/l
—
5
65
217
2238
0.97
0.18
1.1
1.1
9.4
10.3
au/ml
0.08
17
168
59
630
0.93
0.18
1.5
1.4
4.4
5.2
u/l
1.99
44
542
1045
10283
1.02
0.18
2.0
2.0
382.9
376.0
nmol/l
0.55
972
9484
7
59
1.18
0.18
1.1
1.1
—
—
—
0
0
9400
93591
1.01
0.17
14.0
12.9
332.2
331.8
g/l
4.55
9341
92938
364
3545
1.03
0.17
2.0
2.2
4.3
5.0
umol/l
1.42
265
2532
67
629
1.06
0.17
2.8
2.7
177.8
55.6
mg/l
0.62
45
426
5
66
0.76
0.17
1.2
1.2
0.0
0.0
mg/l
—
5
58
29
262
1.10
0.16
6.0
2.5
9.7
9.3
mmol/l
0.16
22
195
32
291
1.10
0.16
2.1
2.1
—
—
—
0
0
466
4561
1.02
0.15
1.2
1.2
11.6
12.1
u/l
0.35
395
3805
36
389
0.92
0.15
2.9
2.5
52.3
49.5
umol/l
0.26
30
331
27
296
0.91
0.15
1.0
1.0
721.5
787.3
ng/l
0.30
19
218
292
2844
1.03
0.15
1.1
1.1
1.3
0.9
u/ml
0.33
108
1149
12
102
1.17
0.14
1.0
1.2
—
1.1
—
0
12
240
2459
0.97
0.14
3.2
2.9
—
—
—
0
0
104
995
1.04
0.14
1.3
1.3
—
—
—
0
0
78
741
1.05
0.14
1.1
1.1
—
—
—
0
0
45
420
1.07
0.14
1.1
1.1
—
—
—
0
0
20
222
0.90
0.14
1.1
1.1
—
210.9
—
0
11
309
3016
1.02
0.14
1.1
1.1
5.3
4.8
u/ml
0.23
145
1536
153
1577
0.97
0.14
3.3
3.0
9.2
9.0
kpa
0.47
148
1550
211
2049
1.03
0.14
1.1
1.0
0.2
0.3
u/ml
0.54
32
396
655
6442
1.02
0.14
3.6
3.1
1.2
1.2
mmol/l
1.71
569
5654
389
3956
0.98
0.13
2.3
2.2
—
—
—
0
0
12
103
1.16
0.13
2.5
7.0
—
—
—
0
0
10
117
0.85
0.13
1.0
1.1
—
—
—
0
0
209
2141
0.97
0.13
3.2
3.7
33.3
28.2
u/ml
0.33
196
2058
46
431
1.07
0.13
1.2
1.1
—
—
—
0
0
19
170
1.12
0.13
1.1
1.2
—
—
—
0
0
109
1129
0.96
0.13
3.2
3.4
226.8
466.2
u/ml
0.46
101
1031
107
1028
1.04
0.13
1.1
1.0
—
—
—
0
0
48
451
1.06
0.13
1.2
1.1
—
—
—
0
0
297
2902
1.02
0.12
1.1
1.1
1.3
1.9
u/ml
0.58
63
705
89
852
1.04
0.12
1.1
1.2
—
—
—
0
0
75
783
0.96
0.12
1.1
1.2
28.5
15.2
u/ml
—
8
90
16
179
0.89
0.12
1.1
1.2
—
—
—
0
0
119
1228
0.97
0.12
1.2
1.2
—
—
—
0
0
384
3897
0.98
0.11
1.5
1.4
0.5
0.5
nmol/l
0.04
310
3121
123
1189
1.03
0.11
1.0
1.1
193.7
205.6
mg/l
0.71
104
1046
188
1831
1.02
0.11
3.1
2.9
7.4
7.4
ph
0.07
149
1537
102
1053
0.97
0.11
1.2
1.1
—
—
—
0
0
17
153
1.11
0.10
1.1
1.1
—
—
—
0
0
23
211
1.09
0.10
1.3
1.2
—
—
—
0
0
46
435
1.06
0.10
1.2
1.2
—
—
—
0
0
14
156
0.90
0.10
3.1
2.0
—
—
—
0
0
51
534
0.95
0.10
1.1
1.1
13.9
8.8
u/ml
—
5
81
248
2428
1.02
0.10
1.2
1.2
3.5
3.6
mmol/l
1.13
239
2268
29
270
1.07
0.10
1.1
1.1
—
—
—
0
0
29
270
1.07
0.10
1.1
1.1
—
—
—
0
0
29
270
1.07
0.10
1.1
1.1
—
—
—
0
0
148
1440
1.03
0.10
1.9
2.0
—
—
—
0
0
55
574
0.96
0.10
1.5
1.4
—
—
—
0
0
238
2330
1.02
0.09
4.5
4.5
1.8
1.7
%
0.48
222
2172
107
1036
1.03
0.09
1.0
1.0
0.9
2.0
u/ml
0.51
21
229
153
1564
0.98
0.09
3.3
2.9
4.9
5.0
kpa
0.91
148
1537
153
1564
0.98
0.09
3.3
2.9
1.9
2.3
mmol/l
1.09
83
951
88
907
0.97
0.09
1.3
1.3
—
—
—
0
0
45
428
1.05
0.09
1.1
1.2
—
—
—
0
0
134
1370
0.98
0.09
1.2
1.2
0.5
1.7
nmol/l
0.75
129
1330
6
58
1.03
0.08
1.2
1.0
—
—
—
0
0
5
60
0.83
0.08
1.0
1.3
—
23.4
—
0
17
5
64
0.78
0.08
1.0
1.0
—
—
—
0
0
7
64
1.09
0.08
2.9
3.0
—
—
—
0
0
942
9332
1.01
0.08
1.3
1.3
—
—
—
0
0
14
127
1.10
0.07
1.0
1.0
0.1
1.5
u/ml
—
5
49
93
904
1.03
0.07
2.2
1.7
—
—
—
0
0
15
137
1.09
0.07
1.7
1.9
—
—
—
0
0
7
82
0.85
0.07
1.9
4.5
—
—
—
0
0
23
244
0.94
0.06
1.0
1.0
—
—
—
0
0
9
101
0.89
0.06
1.3
1.6
—
—
—
0
0
174
1709
1.02
0.06
1.4
1.5
0.5
0.6
g/l
0.96
124
1302
362
3646
0.99
0.05
3.2
2.8
5.2
5.1
kpa
0.87
337
3395
14
151
0.93
0.05
2.8
1.7
6.7
382932.7
nmol/l
—
9
123
52
535
0.97
0.05
1.1
1.1
—
—
—
0
0
234
2309
1.01
0.05
4.6
4.6
0.9
0.9
%
2.40
221
2157
100
979
1.02
0.05
1.1
1.1
1.1
1.1
ratio
0.02
34
365
252
2541
0.99
0.05
1.1
1.1
3.0
4.8
u/ml
0.74
84
954
115
1167
0.98
0.05
1.6
1.4
358.7
388.0
pmol/l
0.24
89
927
238
2400
0.99
0.04
1.1
1.1
3.7
4.7
u/ml
0.54
89
981
79
772
1.02
0.04
3.4
3.6
5.9
7.0
mmol/l
3.23
63
634
20
189
1.06
0.04
2.4
2.1
473.0
793.5
e6/l
0.60
13
117
148
1493
0.99
0.03
3.5
3.5
—
—
—
0
0
125
1262
0.99
0.03
2.2
1.8
50.6
55.5
mu/l
0.14
116
1159
282
2795
1.01
0.03
1.3
1.3
1226.9
857.1
titre
0.51
16
113
11
118
0.93
0.03
2.2
2.4
—
—
—
0
0
96
971
0.99
0.03
1.4
1.5
5.4
5.2
mmol/l
1.21
91
926
339
3364
1.01
0.02
1.1
1.1
1.4
1.3
u/ml
0.05
127
1248
82
830
0.99
0.02
3.0
3.2
—
—
—
0
0
32
310
1.03
0.02
1.3
1.5
—
—
—
0
0
68
668
1.02
0.02
1.0
1.1
0.3
3.4
nmol/l
1.49
11
121
87
857
1.01
0.02
1.3
1.4
—
—
—
0
0
87
857
1.01
0.02
1.3
1.4
—
—
—
0
0
34
348
0.97
0.02
2.1
2.0
—
—
—
0
0
38
388
0.98
0.02
1.3
1.4
11468.8
2787.7
e6/l
0.47
31
281
46
468
0.98
0.02
1.5
1.6
2.1
2.2
u/field
0.04
33
341
87
858
1.01
0.02
1.3
1.4
—
—
—
0
0
87
858
1.01
0.02
1.3
1.4
—
—
—
0
0
397
3947
1.00
0.02
1.8
1.9
20.7
20.7
s
0.06
335
3259
257
2577
1.00
0.01
2.8
2.9
25.5
25.3
mmol/l
0.61
249
2485
34
332
1.02
0.01
1.1
1.4
—
—
—
0
0
138
1386
0.99
0.01
2.7
2.1
17.1
16.9
%
0.30
69
673
209
2076
1.00
0.01
1.2
1.2
—
—
—
0
0
22
213
1.03
0.01
2.7
2.6
—
—
—
0
0
209
2094
1.00
0.01
1.3
1.2
2.8
4.0
u/ml
2.03
98
858
68
672
1.01
0.00
2.4
2.5
—
—
—
0
0
17
166
1.02
0.00
2.2
1.9
—
—
—
0
0
36
356
1.01
0.00
1.0
1.0
5.0
5.1
mg/g
0.04
36
331
46
459
1.00
0.00
1.2
1.4
13.8
13.4
pmol/l
0.20
41
378
90
896
1.00
0.00
1.8
1.6
46.3
48.3
%
0.19
56
550
43
431
1.00
0.00
1.0
1.2
—
—
—
0
0
13
134
0.97
0.00
1.2
1.6
139.0
55.6
ng/l
—
6
73
20
197
1.01
0.00
1.1
1.1
—
—
—
0
0
68
676
1.00
0.00
1.7
1.6
39.8
40.2
%
0.03
42
405
24
235
1.02
0.00
1.1
1.1
—
—
—
0
0
24
235
1.02
0.00
1.1
1.1
—
—
—
0
0
24
235
1.02
0.00
1.1
1.1
—
—
—
0
0
13
127
1.02
0.00
1.4
1.2
—
—
—
0
0
13
127
1.02
0.00
1.0
1.0
0.1
0.4
u/ml
—
7
62
14
140
1.00
0.00
1.1
1.0
—
—
—
0
0
24
242
0.99
0.00
1.1
1.1
—
—
—
0
0
17
171
0.99
0.00
2.6
1.9
1036.6
19518.1
e6/l
—
9
76
20
202
0.99
0.00
1.1
1.0
—
—
—
0
0
51
507
1.00
0.00
1.3
1.2
—
—
—
0
0
55
552
0.99
0.00
1.4
1.6
1639.2
2063.2
ml
—
6
103
58
576
1.00
0.00
1.3
1.2
55.4
69.9
%
—
10
65
34
341
0.99
0.00
1.3
1.2
5.9
5.6
nmol/l
0.18
34
319
32
316
1.01
0.00
2.5
2.3
12.2
15.5
umol/l
—
5
27
31
312
0.99
0.00
1.4
1.5
—
—
—
0
0
6
66
0.91
0.00
1.0
1.1
—
—
—
0
0
7
76
0.92
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
0.00
3.2
3.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
145.3
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
5.0
—
0
6

Mortality – FinRegistry

Association

Association between endpoint N14_CERVICAL_DYSPLASIA_ALL and mortality.

Females

Parameter HR [95% CI] p-value
N14_CERVICAL_DYSPLASIA_ALL 1.091 [0.96, 1.24] 0.167
Birth year 0.993 [0.98, 1.0] 0.085

During the follow-up period (1.1.1998 — 31.12.2019), 1991 out of 62972 females with N14_CERVICAL_DYSPLASIA_ALL died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_CERVICAL_DYSPLASIA_ALL.

N-year risk Females Males
1 0.083% No data
5 0.599% No data
10 1.599% No data
15 3.141% No data
20 5.265% No data

Relationships between endpoints

Index endpoint: N14_CERVICAL_DYSPLASIA_ALL – All dysplastic lesions of the cervix uteri

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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