LSIL lesion of the cervix uteri

N14_CERVICAL_LSIL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N87.0
  • Hospital discharge: ICD-9 6221A
  • Cause of death: ICD-10 N87.0
  • Cause of death: ICD-9 6221A

2 out of 7 registries used, show all original rules.

4823

4. Check minimum number of events

None

4823

5. Include endpoints

None

4823

6. Filter based on genotype QC (FinnGen only)

4823

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 28833 28833 -
Only index persons 28289 28289 -
Unadjusted period prevalence (%)
Whole population 0.83 0.83 -
Only index persons 1.04 1.04 -
Median age at first event (years)
Whole population - 34.92 -
Only index persons - 34.83 -

-FinnGen-

Key figures

All Female Male
Number of individuals 4823 4823 -
Unadjusted period prevalence (%) 1.64 1.64 -
Median age at first event (years) 36.00 36.00 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
4260
Matched controls
42599
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
26.2
323.0
2619
2447
LDA10
NOMESCO Finland
Curettage of cervix uteri
15.2
323.0
1367
1284
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
37.4
323.0
3344
3789
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
24.0
323.0
1902
1387
ULA02
NOMESCO Finland
Kolposcopy
40.5
323.0
3388
3730
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
12.0
323.0
2537
4642
N87.0
ICD-10 Finland
Mild cervical dysplasia
4503599627370496.0
323.0
4093
21
N87.1
ICD-10 Finland
Moderate cervical dysplasia
10.7
317.5
651
706
A63.0
ICD-10 Finland
Anogenital (venereal) warts
8.0
317.0
781
1161
6221A
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI LEVIS]
+∞
180.5
172
*
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
14.9
174.9
301
216
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
6.0
157.7
470
866
LEB00
NOMESCO Finland
Biopsy of vagina
8.6
136.0
309
383
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
8.9
128.2
285
340
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
6.2
113.2
324
560
N89.0
ICD-10 Finland
Mild vaginal dysplasia
32.8
107.9
143
45
ZXC00
NOMESCO Finland
Use of diathermy
12.9
90.7
165
133
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
5.4
84.5
270
531
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.9
84.2
2062
14124
G01AA10
ATC
clindamycin; vaginal
2.0
73.7
1188
6874
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
14.6
72.5
124
87
8326
FHL
Batch conization
18.0
52.8
83
47
R87.0
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of enzymes
35.8
52.0
67
19
N87.9
ICD-10 Finland
Dysplasia of cervix uteri, unspecified
10.6
50.7
100
96
D06BB04
ATC
podophyllotoxin; topical
2.4
44.7
418
1858
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
10.5
44.6
88
85
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
23.0
40.9
59
26
N90.0
ICD-10 Finland
Mild vulvar dysplasia
14.3
38.1
65
46
LDB10
NOMESCO Finland
Cryotherapy of cervix uteri
10.4
37.0
73
71
X86
ICPC
Abnormal cervix smear
4.5
35.6
130
296
LCA06
NOMESCO Finland
Biopsy of endometrium
1.7
34.0
737
4550
C539, 6666, 0
ICD-O-3
NA
4.4
33.0
122
281
D06BB10
ATC
imiquimod; topical
2.6
32.2
240
941
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
30.5
1363
10114
P01AB01
ATC
metronidazole; oral, rectal
1.4
28.4
1809
14385
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
5.8
28.3
81
141
N93.0
ICD-10 Finland
Postcoital and contact bleeding
4.9
26.9
90
188
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
24.9
26.5
37
15
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
46.0
26.5
32
7
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
11.9
25.2
46
39
N72
ICD-10 Finland
Inflammatory disease of cervix uteri
5.4
24.5
75
142
J02AC01
ATC
fluconazole; systemic
1.4
24.5
2233
18786
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.5
21.9
1040
7708
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
14.5
21.6
36
25
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
8.3
20.4
45
55
R87.9
ICD-10 Finland
Abnormal findings in specimens from female genital organs, unspecified abnormal finding
9.6
19.8
40
42
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.5
19.5
687
4757
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1.5
18.6
622
4251
G01AF01
ATC
metronidazole; vaginal
1.6
18.3
492
3185
N76.0
ICD-10 Finland
Acute vaginitis
1.7
17.9
421
2630
X23
ICPC
Fear sexually transm dis female
1.7
17.8
349
2067
LDC00
NOMESCO Finland
Conisation of cervix uteri using knife
17.0
17.4
27
16
R2110
NOMESCO Finland
Giving the first information
1.7
17.0
377
2313
0781C
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Viral warts[CONDYLOMA ACCUMINATUM]
5.0
17.0
54
109
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
16.8
2852
25697
SPAT1193
SPAT
Pap smear
1.5
16.4
684
4901
8325
FHL
Coagulation, cryo or laser in anesthesia or operating room
7.7
15.8
36
47
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.9
15.2
234
1277
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
14.8
2417
21439
N87
ICD-10 Finland
Dysplasia of cervix uteri
12.6
14.3
25
20
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
9.7
14.2
28
29
TLC02
NOMESCO Finland
Simple extraction of IUD
1.7
14.0
294
1775
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
14.4
14.0
23
16
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
2.0
13.8
187
976
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.4
13.3
656
4838
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
13.2
891
6940
N07BA03
ATC
varenicline; oral
1.8
13.1
211
1174
R87.2
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of other drugs, medicaments and biological substances
7.7
12.8
29
38
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
1.6
12.6
329
2110
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
12.5
1150
9378
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.5
12.2
384
2582
X92
ICPC
Chlamydia infection genital female
2.5
11.8
92
374
LDB00
NOMESCO Finland
Excision of lesion of cervix uteri
2.8
11.7
75
275
M03BX02
ATC
tizanidine; oral
1.3
11.5
2573
23363
N02AX02
ATC
tramadol; systemic, rectal
1.3
11.1
1252
10455
J05AB01
ATC
aciclovir; systemic
1.3
11.1
834
6585
SPAT1308
SPAT
Sexual health counselling
1.3
11.0
820
6460
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
11.0
1486
12697
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.3
10.8
1498
12829
X15
ICPC
Vaginal symptom/complaint other
1.7
10.7
206
1217
WX110
NOMESCO Finland
Local anesthesy
1.3
10.6
2834
26132
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
1.3
10.6
903
7261
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
10.5
2407
21802
M54.5
ICD-10 Finland
Low back pain
1.3
10.4
1268
10677
XLA10
NOMESCO Finland
NA
1.6
10.4
247
1548
LCH11
NOMESCO Finland
Pharmacologic abortion
1.6
10.1
286
1874
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.5
10.0
333
2264
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
2.9
9.7
57
198
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
9.6
1563
13578
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
4.1
9.6
36
89
J01CA08
ATC
pivmecillinam; oral
1.2
9.6
2038
18231
N02BE01
ATC
paracetamol; systemic, rectal
1.3
9.5
3366
31815
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
9.4
2999
27971
K05.31
ICD-10 Finland
Periodontitis pronounced
1.6
9.4
214
1324
J01AA02
ATC
doxycycline; systemic
1.2
9.3
3001
28010
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
2.0
9.2
122
634
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
9.2
2087
18756
SDA02
NOMESCO Finland
Parodonthologic therapy
1.2
9.1
1304
11159
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
9.1
1534
13367
J01DB01
ATC
cefalexin; oral
1.3
8.9
3305
31242
L04AX01
ATC
azathioprine; systemic
1.8
8.9
152
866
ULC02
NOMESCO Finland
Hysteroscopy
1.6
8.8
246
1608
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.4
8.8
523
3971
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
8.8
3837
37027
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
2.0
8.7
103
515
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.2
8.5
1155
9804
8474
FHL
Coagulation, excision, or biopsy of local change (eg, condyloma, tumor) in operating room or anesthesia
4.9
8.5
26
53
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.4
8.4
407
2987
D06.1
ICD-10 Finland
Carcinoma in situ: Exocervix
4.7
8.2
26
55
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.4
8.2
419
3102
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.5
8.2
310
2171
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.6
8.2
214
1378
N86
ICD-10 Finland
Erosion and ectropion of cervix uteri
4.3
8.1
28
65
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
8.1
1622
14333
J05AB11
ATC
valaciclovir; oral
1.4
8.1
475
3601
D82
ICPC
Teeth/gum disease
1.2
8.1
1435
12524
Z30.0
ICD-10 Finland
General counselling and advice on contraception
1.4
8.0
377
2748
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.3
8.0
955
7978
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
1.9
7.9
110
588
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
7.7
1963
17725
R87.8
ICD-10 Finland
Abnormal findings in specimens from female genital organs, other abnormal findings
3.9
7.6
29
74
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
7.6
2132
19409
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
1.6
7.6
183
1153
J01DA01
ATC
[U] cefalexin; systemic
1.2
7.4
2444
22570
WX290
NOMESCO Finland
Other blockade of nerve
1.2
7.3
1937
17517
Z30.2
ICD-10 Finland
Sterilization
1.3
7.3
521
4070
ZXC10
NOMESCO Finland
Use of laser
2.2
7.3
69
316
8077/2-C53.1
ICD-O-3
Squamous intraepithelial neoplasia, high grade of exocervix
6.2
7.2
18
29
J01EA01
ATC
trimethoprim; systemic
1.2
7.1
1015
8634
A05
ICPC
Feeling ill
1.5
7.1
212
1410
Z71.8
ICD-10 Finland
Other specified counselling
1.2
7.1
931
7848
8411
FHL
Local change laser, coagulation, biopsy or removal
5.6
7.0
19
34
W11
ICPC
Contraception oral
1.3
7.0
505
3948
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
2.0
7.0
88
454
D19
ICPC
Teeth/gum symptom/complaint
1.2
7.0
1030
8795
R05
ICPC
Cough
1.3
6.9
770
6365
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
6.9
2856
26819
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
6.9
1473
13039
R87.1
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of hormones
5.4
6.9
19
35
N05CF01
ATC
zopiclone; oral
1.2
6.8
901
7596
N30.0
ICD-10 Finland
Acute cystitis
1.3
6.8
505
3963
Z01.2
ICD-10 Finland
Dental examination
1.2
6.8
1657
14841
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
1.8
6.7
113
644
O34.4
ICD-10 Finland
Maternal care for other abnormalities of cervix
4.1
6.7
24
59
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
6.7
2157
19790
P01
ICPC
Feeling anxious/nervous/tense
1.3
6.7
502
3951
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.3
6.7
405
3085
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
6.6
1440
12760
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
1.2
6.5
794
6635
8113
FHL
Fractional scraping
1.7
6.4
125
749
R74
ICPC
Upper respiratory infection acute
1.2
6.4
1355
11970
N06AB04
ATC
citalopram; systemic
1.2
6.4
779
6511
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.3
6.3
414
3187
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.3
6.3
677
5568
Z09.9
ICD-10 Finland
Follow-up examination after unspecified treatment for other conditions
2.2
6.3
58
265
WZA90
NOMESCO Finland
Other doctors statement
1.2
6.3
786
6584
K02.1
ICD-10 Finland
Caries of dentine
1.2
6.2
2344
21737
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
1.8
6.1
97
543
KMAK
NOMESCO Finland
NA
1.2
6.1
2285
21149
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.2
6.1
997
8581
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
1.6
6.1
142
893
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
1.6
6.1
162
1054
T36
ICD-10 Finland
Poisoning by systemic antibiotics
1.5
6.1
171
1127
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
1.4
6.0
324
2422

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
869
1151
8.99
307.65
2.5
1.6
—
—
—
0
0
2668
17874
2.10
135.09
2.6
1.9
—
—
—
0
0
472
2954
1.66
22.10
1.3
1.4
—
—
—
0
0
853
6605
1.35
13.47
1.7
1.6
—
—
—
0
0
664
5018
1.37
12.15
2.6
2.4
4.4
4.6
e6/l
0.17
351
2536
1129
9291
1.28
11.25
3.3
3.3
—
—
—
0
0
1613
13871
1.24
11.00
2.2
2.0
—
—
—
0
0
3239
30039
1.24
10.56
4.1
3.8
9.7
9.9
mm/h
0.57
3073
28315
2996
27605
1.23
10.18
4.0
3.9
1191.3
1896.7
e6/l
0.44
27
302
3087
28544
1.23
10.08
7.1
6.6
71.0
72.2
u/l
1.01
2900
26988
691
5408
1.32
9.93
2.4
2.3
1.1
1.1
e6/l
0.04
375
2907
3090
28609
1.22
9.80
4.2
3.9
—
—
—
0
0
2240
20133
1.21
9.49
6.2
5.7
0.5
0.5
e9/l
0.75
1988
17850
1170
9855
1.25
9.32
6.3
6.4
—
—
—
0
0
1498
12957
1.23
9.31
3.5
3.2
58.9
69.7
e6/l
0.58
978
8391
2240
20213
1.20
8.87
6.3
5.7
0.0
0.0
e9/l
0.14
1985
17873
1193
10147
1.23
8.58
2.9
2.7
24.6
80.2
e6/l
3.09
878
7555
1102
9298
1.24
8.54
2.7
2.6
—
—
—
0
0
1095
9243
1.24
8.43
2.8
2.6
0.4
0.3
e6/l
1.08
791
6774
2271
20581
1.20
8.41
3.3
3.2
0.0
0.0
estimate
0.08
436
4017
2518
23046
1.19
8.30
8.5
8.4
3.9
3.9
e9/l
0.17
2216
20411
453
3438
1.35
7.98
2.3
2.2
41.5
35.0
u/l
0.35
388
2922
1452
12676
1.21
7.95
6.3
5.8
—
—
—
0
0
2087
18863
1.19
7.72
6.2
5.7
2.8
2.8
%
0.02
1948
17641
2301
20988
1.18
7.62
6.4
5.9
0.2
0.2
e9/l
0.41
2107
18897
2675
24722
1.18
7.56
2.8
2.8
—
—
—
0
0
2293
20926
1.18
7.50
6.2
5.6
2.0
2.0
e9/l
0.23
2111
18913
1978
17832
1.19
7.45
8.1
7.9
0.0
0.0
e9/l
1.31
1621
14685
2283
20849
1.18
7.35
3.3
3.3
0.0
0.0
estimate
0.04
439
4080
2091
18963
1.18
7.29
6.4
5.9
7.9
7.9
%
0.17
1967
17898
2267
20708
1.18
7.23
4.5
4.4
0.0
0.0
estimate
0.46
448
4146
2009
18186
1.18
7.10
6.3
5.8
0.7
0.7
%
0.37
1876
17007
1605
14276
1.19
6.94
4.6
4.7
1.2
1.2
mmol/l
0.20
1493
13054
192
1288
1.51
6.75
1.2
1.1
—
—
—
0
0
1110
9572
1.21
6.73
3.9
3.5
7.4
7.4
ph
0.29
179
1868
778
6473
1.24
6.70
2.5
2.4
100.7
98.3
ug/g
0.08
616
5056
364
2755
1.35
6.55
1.3
1.2
—
—
—
0
0
4512
44111
1.35
6.20
9.9
9.7
—
—
—
0
0
4119
39820
1.24
6.17
10.4
9.9
139.6
139.6
mmol/l
0.21
4023
38774
2154
19766
1.16
6.09
6.2
5.7
30.4
29.8
%
2.17
2014
18603
1038
8975
1.20
6.04
3.8
3.2
95.9
98.6
%
3.37
1004
8672
2129
19530
1.16
6.02
6.1
5.5
55.8
56.5
%
2.11
1998
18430
4128
39945
1.23
5.95
10.5
10.0
3.9
3.9
mmol/l
0.47
4023
38788
1993
18270
1.15
5.53
5.3
5.2
9.5
9.5
umol/l
0.16
1875
17218
1742
15821
1.16
5.48
3.1
3.0
—
6.1
—
0
6
1486
13336
1.17
5.47
1.8
1.8
98.2
99.6
pmol/l
0.60
810
7148
998
8708
1.18
5.16
3.6
3.5
1.0
1.0
kg/l
0.70
134
1279
1758
16030
1.15
5.15
5.4
5.3
1.2
1.2
mmol/l
0.08
1535
13537
204
1470
1.40
5.03
1.3
1.4
26.4
23.7
u/l
0.62
172
1216
4264
41559
1.22
4.78
11.3
10.3
18.3
18.4
mg/l
0.06
3325
31967
1219
10880
1.16
4.71
3.5
3.5
0.0
0.0
estimate
2.55
449
4106
245
1855
1.34
4.48
1.8
1.7
—
—
—
0
0
133
910
1.47
4.38
1.9
1.9
—
—
—
0
0
515
4293
1.22
4.33
1.5
1.4
—
—
—
0
0
628
5341
1.20
4.30
1.2
1.2
—
—
—
0
0
4094
39831
1.18
4.22
5.2
5.1
2.3
1.9
mu/l
0.31
3905
37878
237
1806
1.33
4.17
1.7
1.7
—
—
—
0
0
4723
46734
1.51
4.09
16.4
15.5
30.2
30.0
pg
20.20
4682
46339
122
833
1.48
4.09
3.1
3.3
277.2
329.4
u/ml
0.06
103
707
4723
46735
1.51
4.08
16.4
15.5
90.8
90.2
fl
19.36
4682
46342
3677
35516
1.15
4.02
4.5
4.5
14.3
14.3
pmol/l
0.20
3482
33516
4723
46741
1.50
4.01
16.5
15.6
4.4
4.5
e12/l
5.95
4621
45868
143
1013
1.42
3.96
1.6
1.6
—
—
—
0
0
4723
46748
1.50
3.92
16.5
15.6
6.7
6.7
e9/l
0.43
4622
45836
955
8477
1.16
3.90
1.3
1.3
9.4
8.9
u/ml
0.12
418
3653
4421
43374
1.23
3.87
9.4
8.6
23.7
23.8
u/l
0.05
4319
42197
4723
46759
1.49
3.79
16.5
15.7
133.3
133.0
g/l
1.07
4686
46354
269
2116
1.29
3.78
1.3
1.3
2.5
1.1
u/ml
0.50
25
185
1482
13578
1.13
3.78
3.4
2.9
30.8
28.6
u/l
0.37
1415
13012
140
999
1.41
3.75
3.1
2.5
—
—
—
0
0
1281
11638
1.14
3.72
1.3
1.3
1.4
1.6
u/ml
0.17
405
3437
3544
34212
1.14
3.68
4.1
4.2
36.8
37.5
mmol/mol
6.91
3354
32404
3743
36274
1.14
3.61
13.4
12.5
13.5
13.5
%
0.40
3681
35601
735
6432
1.17
3.61
2.5
2.4
498.8
522.7
mosm/kgh2o
2.13
631
5453
492
4160
1.20
3.60
3.2
2.3
5.3
6.0
umol/l
0.67
420
3503
483
4080
1.20
3.57
1.4
1.4
—
—
—
0
0
234
1824
1.30
3.55
2.4
2.7
—
—
—
0
0
800
7070
1.16
3.45
2.4
2.3
8.1
8.5
e6/l
0.22
686
6109
1021
9182
1.14
3.43
1.8
2.0
116.0
137.4
u/l
1.36
978
8707
1288
11762
1.13
3.41
1.7
1.7
—
—
—
0
0
491
4174
1.20
3.40
1.4
1.3
—
—
—
0
0
615
5331
1.18
3.40
2.8
2.8
132.5
345.0
ng/l
2.50
325
2830
256
2036
1.27
3.33
1.1
1.1
53.2
3.0
u/ml
—
6
27
4715
46705
1.43
3.32
16.5
15.6
270.1
269.5
e9/l
0.31
4619
45886
314
2561
1.24
3.30
2.3
2.6
—
—
—
0
0
1257
11483
1.13
3.29
2.6
2.5
—
—
—
0
0
23
102
2.26
3.28
4.0
2.5
—
—
—
0
0
34
176
1.94
3.28
1.9
2.5
147.9
167.7
umol/l
0.16
23
97
650
5679
1.17
3.26
2.4
2.5
2.4
2.4
mmol/l
0.19
548
4952
47
271
1.74
3.24
1.1
1.2
526.7
211.3
titre
—
9
61
152
1135
1.35
3.15
2.3
2.6
—
—
—
0
0
251
2007
1.26
3.15
2.3
2.1
—
—
—
0
0
559
4841
1.18
3.13
2.9
3.0
0.8
0.8
mmol/l
0.10
517
4542
981
8853
1.14
3.11
1.4
1.3
28.5
26.3
iu/ml
0.19
317
2801
1048
9499
1.13
3.10
1.6
1.7
0.9
0.8
mg/l
0.19
769
7031
4058
39649
1.15
3.07
3.5
3.5
4.8
4.9
mmol/l
0.90
3887
37773
3894
37948
1.14
3.04
3.6
3.5
5.6
5.6
mmol/l
1.59
3663
35660
150
1128
1.34
2.99
3.5
3.5
24.1
24.2
mmol/l
0.12
138
1002
4091
40013
1.15
2.97
3.8
3.8
2.9
2.9
mmol/l
0.56
3883
37864
319
2640
1.22
2.95
1.4
1.3
219.2
237.3
miu/ml
0.43
171
1357
45
265
1.70
2.91
3.0
2.8
693.3
847.0
e6/l
0.67
16
119
1529
14211
1.11
2.90
4.7
4.1
36.9
36.7
g/l
0.56
1431
13281
761
6784
1.14
2.90
1.4
1.4
552.0
608.3
titre
0.38
174
1378
49
296
1.66
2.89
3.3
2.6
—
—
—
0
0
188
1467
1.29
2.89
2.5
2.0
0.2
0.2
g/l
0.54
174
1386
24
115
2.09
2.88
1.1
1.2
—
—
—
0
0
311
2576
1.22
2.86
3.6
3.2
—
—
—
0
0
1861
17488
1.10
2.84
2.3
2.3
76.9
74.9
nmol/l
2.48
1731
16366
44
260
1.70
2.82
2.1
2.8
—
—
—
0
0
3886
37910
1.13
2.82
3.2
3.2
1.2
1.2
mmol/l
0.61
3695
35979
531
4624
1.17
2.79
1.7
1.8
—
—
—
0
0
290
2398
1.22
2.73
2.3
2.0
—
—
—
0
0
1070
9783
1.12
2.72
1.4
1.4
2.2
2.1
g/l
1.18
656
6281
325
2720
1.21
2.71
1.1
1.1
413.7
230.0
titre
—
8
78
4033
39459
1.13
2.70
3.5
3.5
1.6
1.6
mmol/l
0.24
3846
37521
33
182
1.82
2.68
3.9
2.9
—
—
—
0
0
413
3540
1.18
2.65
5.9
4.7
1.1
1.0
mmol/l
0.39
386
3315
1051
9615
1.12
2.64
1.7
1.7
—
—
—
0
0
288
2389
1.22
2.63
1.4
1.3
—
—
—
0
0
1024
9364
1.12
2.59
1.6
1.6
1.4
1.3
mmol/l
0.20
904
8169
35
200
1.76
2.55
3.7
2.6
38.3
46.2
%
—
7
78
315
2649
1.20
2.51
2.2
2.0
—
—
—
0
0
45
277
1.63
2.51
1.8
2.3
—
—
—
0
0
424
3660
1.17
2.51
3.0
3.4
4.6
4.5
pmol/l
0.28
371
3303
507
4438
1.16
2.51
1.6
1.6
—
—
—
0
0
79
555
1.43
2.43
2.4
2.2
—
—
—
0
0
186
1488
1.26
2.40
1.3
1.3
40.5
33.0
u/ml
0.24
24
113
311
2629
1.20
2.36
2.2
2.0
—
—
—
0
0
312
2640
1.19
2.35
2.2
1.9
—
—
—
0
0
189
1520
1.25
2.34
2.5
1.9
1.1
1.2
g/l
1.26
177
1440
1026
9446
1.11
2.28
1.9
1.9
—
—
—
0
0
279
2351
1.20
2.21
1.1
1.1
—
—
—
0
0
50
327
1.53
2.21
2.7
2.1
39.8
46.8
%
—
6
49
781
7096
1.12
2.21
1.5
1.4
21.5
21.3
nmol/l
0.21
693
6288
554
4937
1.14
2.15
1.3
1.3
25.9
26.3
iu/l
0.10
490
4302
1218
11344
1.10
2.14
2.4
2.4
53.0
57.1
u/l
3.17
1136
10549
306
2618
1.18
2.06
2.3
1.9
—
—
—
0
0
360
3125
1.16
2.03
1.2
1.2
—
—
—
0
0
30
177
1.70
2.01
2.3
2.0
9.1
10.0
mg/l
0.30
25
143
492
4372
1.14
2.01
2.0
2.0
29.4
29.1
s
0.73
479
4217
348
3020
1.16
1.98
2.8
2.6
10.5
10.4
g/l
0.15
325
2789
67
477
1.41
1.97
1.3
1.4
—
—
—
0
0
1355
12729
1.09
1.95
2.0
2.0
—
—
—
0
0
78
572
1.37
1.94
2.5
1.7
32.3
34.3
iu/ml
—
9
31
39
250
1.56
1.92
2.8
2.8
—
22.3
—
0
6
376
3291
1.15
1.92
2.3
2.3
20.8
23.3
au/ml
0.24
20
260
348
3031
1.16
1.90
5.7
6.1
104.9
104.8
mmol/l
0.06
340
2969
38
243
1.57
1.89
1.1
1.1
5.2
7.6
u/ml
—
6
49
334
2901
1.16
1.89
13.7
13.2
1.1
1.1
inr
0.19
35
489
25
144
1.74
1.84
1.9
1.7
154.6
169.1
au/ml
—
5
21
104
804
1.30
1.83
1.3
1.2
2.8
4.2
u/ml
1.42
48
324
7
23
3.05
1.80
6.3
10.2
4.1
5.4
mmol/l
—
7
23
7
24
2.92
1.72
1.0
1.8
—
—
—
0
0
0
46
0.00
1.70
0.0
1.1
—
—
—
0
0
2080
19970
1.07
1.67
3.6
3.8
—
—
—
0
0
258
2222
1.17
1.66
3.5
3.2
72.4
73.4
ng/l
0.08
238
1974
17
305
0.56
1.66
8.2
11.9
758.6
859.3
nmol/l
0.31
17
293
386
3427
1.14
1.64
2.2
2.7
33.3
37.5
u/ml
0.34
367
3322
75
564
1.33
1.64
1.3
1.3
—
—
—
0
0
563
5114
1.11
1.63
1.6
1.7
1211.7
1192.8
nmol/l
0.20
462
4017
65
480
1.36
1.60
4.3
5.5
387.6
370.7
umol/l
0.36
55
411
482
4347
1.12
1.59
1.5
1.4
—
—
—
0
0
122
984
1.25
1.57
1.3
1.3
324.4
310.7
ug/g
0.35
78
502
230
1973
1.17
1.57
5.9
7.1
—
—
—
0
0
24
144
1.67
1.57
1.0
1.1
—
—
—
0
0
152
1256
1.22
1.56
7.6
7.4
—
—
—
0
0
27
168
1.61
1.54
1.1
1.2
—
—
—
0
0
10
44
2.28
1.53
1.2
1.3
—
—
—
0
0
505
4580
1.11
1.52
2.2
2.2
3974.5
6161.2
u/l
0.72
185
1916
2118
20407
1.07
1.48
3.9
3.8
6.2
6.3
mmol/l
1.25
1945
18347
240
2082
1.16
1.44
3.3
3.2
2.0
1.8
mmol/l
0.46
199
1685
228
1971
1.16
1.44
8.1
6.7
8.2
7.2
mmol/l
1.55
220
1891
5
16
3.13
1.44
1.0
1.0
—
—
—
0
0
19
316
0.60
1.43
9.1
16.9
1312.8
4548.2
nmol/l
0.54
19
303
342
3043
1.13
1.43
1.2
1.3
34.5
38.2
au/ml
0.13
11
129
73
561
1.31
1.41
4.3
3.5
38.6
42.3
mg/l
0.16
60
455
161
1355
1.19
1.40
1.4
1.3
20.1
9.0
u/ml
0.76
34
235
1244
11791
1.07
1.40
3.0
3.0
2.3
2.3
mmol/l
1.55
1113
10638
73
562
1.30
1.40
4.3
3.5
32.1
31.0
mg/l
0.06
60
456
219
1896
1.16
1.37
1.6
1.7
—
—
—
0
0
247
2158
1.15
1.37
3.2
3.2
—
7.4
—
0
10
145
1212
1.20
1.36
1.3
1.3
37.4
41.0
u/ml
0.12
15
130
1017
9579
1.08
1.35
2.2
2.1
2.7
2.7
mg/l
0.44
875
8267
2405
23313
1.06
1.35
3.0
3.0
69.0
68.5
ug/l
0.08
2293
22177
241
2104
1.15
1.35
3.3
3.2
5.9
5.8
kpa
0.80
236
2030
1167
11050
1.07
1.35
2.5
2.6
22.2
28.9
ng/l
0.38
470
4784
147
1234
1.20
1.33
1.1
1.1
—
—
—
0
0
158
1336
1.19
1.32
1.4
1.3
17.2
5.2
u/ml
0.78
28
140
22
136
1.62
1.32
1.0
1.1
4.9
4.8
mg/g
0.04
22
131
53
393
1.35
1.32
1.7
2.5
60.0
61.6
%
0.20
53
393
13
232
0.56
1.30
1.6
2.0
—
—
—
0
0
1262
11999
1.07
1.29
2.7
2.8
—
—
—
0
0
8
34
2.36
1.29
1.0
1.1
1.5
1.4
umol/24h
—
8
34
1621
16887
0.94
1.28
2.1
2.2
—
—
—
0
0
29
425
0.68
1.27
1.8
2.4
6.3
7.1
mmol/l
1.32
29
414
302
2691
1.13
1.27
3.4
3.6
34.9
29.1
ug/l
0.08
223
1957
449
4094
1.11
1.26
1.2
1.2
—
—
—
0
0
17
101
1.69
1.19
1.4
6.6
53.5
62.2
mg/l
0.25
12
71
18
109
1.65
1.18
1.7
1.5
—
—
—
0
0
46
614
0.75
1.18
3.9
3.6
—
—
—
0
0
103
847
1.22
1.18
1.2
1.3
—
—
—
0
0
52
393
1.33
1.17
1.1
1.2
—
—
—
0
0
63
490
1.29
1.16
1.3
1.3
—
—
—
0
0
566
5242
1.09
1.16
1.2
1.2
—
—
—
0
0
101
832
1.22
1.15
1.6
1.4
12.7
9.7
iu/ml
—
6
15
12
210
0.57
1.14
1.1
1.1
—
—
—
0
0
0
36
0.00
1.14
0.0
2.1
—
1.2
—
0
24
19
295
0.64
1.13
1.6
1.5
—
—
—
0
0
37
267
1.39
1.12
1.1
1.1
—
—
—
0
0
55
423
1.30
1.11
4.7
3.7
—
—
—
0
0
68
538
1.27
1.11
1.5
1.7
—
—
—
0
0
21
135
1.56
1.11
1.1
1.3
—
—
—
0
0
919
8697
1.07
1.08
2.3
2.1
1446.5
2526.0
umol/l
0.81
817
7758
758
7127
1.08
1.07
3.6
3.7
—
—
—
0
0
95
784
1.22
1.07
4.0
2.9
1.4
1.3
mg/l
0.40
89
740
15
89
1.69
1.07
1.7
1.8
—
—
—
0
0
21
315
0.67
1.07
1.5
5.7
5.5
7.3
mmol/l
2.81
14
265
60
470
1.28
1.07
1.3
1.4
—
—
—
0
0
117
986
1.19
1.07
1.2
1.3
74.0
21.6
e6/l
0.84
86
767
117
986
1.19
1.07
1.3
1.3
34649.2
1616.7
e6/l
0.48
88
808
3013
29525
1.05
1.04
2.9
2.7
33.6
33.4
u/l
0.05
2905
28240
504
4677
1.09
1.01
1.2
1.2
144.9
152.1
iu/ml
0.16
181
1914
27
188
1.44
1.01
1.8
2.3
9.8
10.9
%
0.58
27
188
17
262
0.65
1.00
1.1
1.3
—
—
—
0
0
12
201
0.60
0.99
1.2
1.1
—
—
—
0
0
34
460
0.74
0.99
1.7
2.4
1.2
1.4
mmol/l
0.69
34
447
60
476
1.26
0.98
1.3
1.4
0.4
0.4
g/l
0.23
42
331
60
476
1.26
0.98
1.3
1.4
7.8
6.4
g/l
1.33
42
333
60
476
1.26
0.98
1.3
1.4
2.6
2.9
g/l
1.21
43
331
942
8953
1.06
0.98
3.3
3.1
7.5
7.4
mmol/l
0.22
816
7750
5
23
2.18
0.98
1.0
1.7
—
—
—
0
0
7
135
0.52
0.98
1.1
1.2
—
—
—
0
0
0
30
0.00
0.97
0.0
4.2
—
—
—
0
0
16
100
1.60
0.96
1.1
1.1
—
—
—
0
0
257
2314
1.12
0.96
1.9
1.8
1.3
1.4
g/l
0.45
238
2152
45
581
0.77
0.96
2.9
2.6
—
—
—
0
0
442
4092
1.09
0.95
2.1
2.1
384.9
376.7
nmol/l
0.35
416
3770
26
183
1.42
0.93
2.8
2.1
—
—
—
0
0
84
698
1.21
0.92
1.5
1.5
0.5
0.6
g/l
0.73
62
526
50
392
1.28
0.92
1.0
1.0
—
—
—
0
0
18
118
1.53
0.90
1.0
1.1
—
0.7
—
0
5
49
384
1.28
0.90
1.1
1.3
—
—
—
0
0
177
1567
1.13
0.89
1.2
1.2
—
—
—
0
0
30
404
0.74
0.88
1.1
1.2
0.1
0.7
u/ml
—
7
147
8
45
1.78
0.84
1.1
1.1
—
—
—
0
0
35
265
1.32
0.84
1.0
1.1
0.5
3.8
nmol/l
—
7
47
136
1190
1.15
0.83
1.2
1.2
—
—
—
0
0
60
488
1.23
0.83
1.1
1.2
33.4
34.7
mg/l
0.11
53
411
171
1520
1.13
0.83
2.7
2.2
—
—
—
0
0
34
257
1.33
0.82
2.0
2.3
51.3
54.8
%
0.46
23
168
18
121
1.49
0.82
3.2
2.7
30.7
28.1
umol/l
0.60
13
88
1083
10398
1.05
0.81
3.7
3.9
—
—
—
0
0
173
1543
1.13
0.80
2.0
1.8
20.8
20.5
s
0.42
149
1261
238
2162
1.11
0.79
4.5
5.8
1.1
1.2
mmol/l
1.79
226
2090
1149
11055
1.05
0.79
5.3
5.5
1.1
1.1
inr
0.19
370
3698
0
25
0.00
0.79
0.0
6.4
—
—
—
0
0
78
657
1.19
0.78
1.0
1.1
—
—
—
0
0
0
27
0.00
0.77
0.0
7.0
—
—
—
0
0
188
1690
1.12
0.77
2.4
2.7
4.3
4.6
kpa
1.29
182
1625
38
296
1.29
0.76
1.1
1.1
—
—
—
0
0
16
107
1.50
0.76
1.2
2.5
—
—
—
0
0
41
323
1.27
0.76
1.2
1.2
—
—
—
0
0
118
1031
1.15
0.75
1.8
1.9
1.4
1.4
g/l
0.03
103
887
128
1125
1.14
0.75
1.2
1.2
484.8
460.2
mg/l
0.12
121
1078
13
83
1.57
0.74
3.2
5.1
—
—
—
0
0
11
172
0.64
0.73
2.5
2.3
560.0
597.0
ml
0.19
11
135
44
352
1.25
0.73
1.0
1.1
4.8
9.1
iu/ml
1.33
16
95
638
6714
0.94
0.72
2.0
2.1
—
—
—
0
0
78
663
1.18
0.72
1.6
1.5
—
—
—
0
0
161
1442
1.12
0.72
2.3
2.1
4.1
4.3
iu/l
0.13
68
604
27
355
0.76
0.71
1.1
1.2
—
—
—
0
0
7
41
1.71
0.70
1.1
2.4
19.3
21.4
mg/l
—
7
41
18
251
0.72
0.69
1.7
1.9
2.5
2.1
u/field
—
10
131
9
146
0.62
0.69
1.2
1.5
—
—
—
0
0
5
27
1.85
0.68
1.0
1.3
12.2
19.1
%
—
5
21
11
69
1.60
0.68
1.1
1.1
—
—
—
0
0
174
1572
1.11
0.68
2.5
2.8
—
—
—
0
0
103
901
1.15
0.67
1.2
1.2
332.0
262.5
u/ml
1.36
71
612
80
687
1.17
0.66
1.0
1.1
—
—
—
0
0
62
735
0.84
0.66
2.6
2.7
7.4
7.4
ph
1.24
51
606
19
136
1.40
0.66
2.7
2.1
15.3
16.5
umol/l
0.24
19
136
19
136
1.40
0.66
1.8
2.3
169.5
161.0
nmol/l
0.14
19
115
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
265
2449
1.09
0.65
1.4
1.4
—
—
—
0
0
119
1055
1.13
0.64
3.0
2.9
0.3
0.3
g/l
0.28
50
393
51
613
0.83
0.64
2.6
2.7
1.4
2.4
mmol/l
3.37
28
382
603
6329
0.95
0.63
1.3
1.3
—
—
—
0
0
36
288
1.25
0.62
1.8
1.3
—
—
—
0
0
8
49
1.63
0.62
1.5
1.6
1.9
0.6
mmol/l
—
8
44
42
343
1.23
0.61
1.2
1.5
—
—
—
0
0
42
343
1.23
0.61
1.2
1.5
—
—
—
0
0
42
343
1.23
0.61
1.2
1.5
—
—
—
0
0
42
343
1.23
0.61
1.2
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
0.1
—
0
15
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
0.1
—
0
12
148
1337
1.11
0.60
1.4
1.6
2.4
8.1
u/ml
—
5
38
0
21
0.00
0.60
0.0
1.1
—
0.5
—
0
5
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
12
80
1.50
0.59
1.3
2.2
—
—
—
0
0
505
4799
1.06
0.58
2.4
2.2
2.4
2.5
g/l
0.83
466
4451
8
53
1.51
0.58
1.1
1.2
—
—
—
0
0
48
572
0.84
0.57
5.1
4.3
64.0
76.4
u/ml
—
9
192
12
81
1.48
0.57
1.2
1.2
—
—
—
0
0
16
115
1.39
0.56
1.1
1.9
1.6
1.9
ug/l
—
9
64
14
98
1.43
0.56
3.6
1.6
—
—
—
0
0
132
1461
0.90
0.56
3.4
2.8
7.4
7.4
ph
0.80
13
205
92
813
1.13
0.55
1.2
1.2
—
—
—
0
0
170
1556
1.10
0.55
2.5
2.4
0.3
0.2
e6/l
0.55
160
1481
29
231
1.26
0.53
2.6
2.5
—
—
—
0
0
55
469
1.17
0.53
1.0
1.1
190.2
205.1
mg/l
0.62
49
417
112
1005
1.12
0.53
1.1
1.1
—
—
—
0
0
559
5346
1.05
0.53
2.4
2.2
14.7
14.3
umol/l
0.78
527
4966
25
316
0.79
0.52
7.3
6.7
—
—
—
0
0
112
1006
1.12
0.52
1.1
1.1
—
—
—
0
0
30
241
1.25
0.52
1.4
1.5
9577.1
44284.4
e6/l
0.68
21
166
297
2791
1.07
0.51
2.6
2.2
0.2
0.2
g/l
0.26
281
2643
741
7142
1.04
0.51
1.5
1.4
—
—
—
0
0
17
225
0.75
0.50
1.2
1.5
—
2386.1
—
0
40
118
1066
1.11
0.50
2.8
2.1
9.4
10.5
mg/l
0.91
113
1005
696
7227
0.96
0.50
1.6
1.6
85342448.5
33482218.4
pmol/l
0.91
614
6287
6
41
1.46
0.50
1.2
1.2
—
2.3
—
0
8
34
279
1.22
0.50
1.4
1.5
69.4
72.1
%
0.39
34
265
287
2699
1.07
0.49
2.6
2.5
1.7
1.7
%
0.37
257
2399
35
289
1.21
0.48
1.5
1.6
1.2
1.3
promille
0.27
29
220
22
172
1.28
0.48
1.2
1.2
—
—
—
0
0
98
880
1.12
0.48
1.1
1.1
5.4
11.0
au/ml
—
8
60
81
719
1.13
0.47
2.4
2.6
—
—
—
0
0
36
299
1.21
0.47
3.7
2.6
—
—
—
0
0
33
272
1.21
0.47
1.5
1.5
340.3
456.8
mu/l
1.11
33
258
356
3751
0.95
0.47
3.1
3.3
—
—
—
0
0
38
318
1.20
0.47
1.4
1.6
6.0
5.9
mmol/l
0.04
27
254
55
476
1.16
0.46
2.8
2.8
34.3
33.3
umol/l
0.10
48
422
246
2620
0.94
0.46
3.6
3.1
1.2
1.2
mmol/l
2.09
213
2283
75
665
1.13
0.45
1.8
1.8
7220.4
8025.5
e6/l
0.18
54
484
56
487
1.15
0.45
1.9
2.7
—
—
—
0
0
26
210
1.24
0.45
2.7
2.5
—
—
—
0
0
136
1479
0.92
0.44
3.4
2.8
5.1
5.1
kpa
0.34
129
1389
75
667
1.13
0.44
2.5
2.0
39.5
39.0
g/l
0.31
67
607
7
51
1.37
0.44
2.1
2.8
—
—
—
0
0
34
405
0.84
0.44
1.1
1.1
—
—
—
0
0
110
1001
1.10
0.43
1.2
1.2
3.4
3.6
mmol/l
2.18
105
942
54
618
0.87
0.43
4.4
2.5
0.8
0.8
nmol/l
0.17
44
529
8
56
1.43
0.42
1.1
1.1
—
—
—
0
0
76
679
1.12
0.42
1.5
1.3
54.7
57.0
u/ml
—
7
50
12
87
1.38
0.42
2.7
1.7
—
—
—
0
0
102
927
1.10
0.42
1.2
1.1
—
—
—
0
0
77
859
0.89
0.42
5.4
5.5
1.1
1.2
mmol/l
0.58
71
751
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
0.1
—
0
7
0
17
0.00
0.40
0.0
1.1
—
37.7
—
0
17
8
60
1.33
0.40
1.1
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
70.1
—
0
18
7
104
0.67
0.39
1.3
1.0
—
—
—
0
0
7
104
0.67
0.39
1.3
1.0
—
—
—
0
0
7
104
0.67
0.39
1.3
1.0
—
—
—
0
0
41
353
1.16
0.39
1.8
1.8
51.3
51.0
%
0.02
26
203
41
353
1.16
0.39
1.7
1.6
—
—
—
0
0
143
1327
1.08
0.38
1.3
1.3
—
—
—
0
0
10
136
0.73
0.37
1.4
1.4
28500.0
118909.1
e6/l
—
5
77
48
546
0.88
0.37
2.1
2.0
17.1
16.8
%
0.21
19
261
72
798
0.90
0.36
2.0
1.9
1.4
2.1
ug/l
0.46
64
710
294
2801
1.05
0.36
3.9
4.1
0.0
0.3
%
0.85
55
537
77
850
0.90
0.36
2.7
3.5
58.9
57.3
%
0.87
77
850
100
917
1.09
0.36
4.7
4.2
—
—
—
0
0
50
441
1.14
0.35
1.5
1.4
311.5
333.4
pmol/l
0.17
36
350
13
168
0.77
0.35
1.3
1.4
39.1
35.1
g/l
0.53
13
157
54
479
1.13
0.35
2.4
1.6
79.5
46.4
mu/l
0.57
49
440
30
254
1.18
0.35
2.9
3.0
136.5
62.3
mg/l
0.28
20
183
320
3061
1.05
0.34
1.4
1.6
288.4
307.9
mu/l
0.52
294
2706
4029
40080
1.03
0.34
12.1
11.1
39.7
39.5
%
1.29
3360
32943
6
44
1.36
0.34
1.5
1.6
—
—
—
0
0
53
595
0.89
0.34
1.6
2.0
—
—
—
0
0
19
154
1.23
0.33
2.7
2.1
—
—
—
0
0
57
636
0.89
0.33
1.8
2.0
129.4
130.5
g/l
0.18
37
475
158
1683
0.94
0.33
1.3
1.3
2.8
3.5
ug/l
1.58
146
1547
102
941
1.09
0.33
1.2
1.3
—
—
—
0
0
6
88
0.68
0.33
1.0
1.0
—
—
—
0
0
86
788
1.09
0.32
2.5
2.1
583.8
299.2
ug/l
0.35
73
687
21
173
1.21
0.32
1.3
1.9
—
—
—
0
0
47
416
1.13
0.32
3.2
2.4
1.2
1.3
e9/l
0.21
26
248
111
1029
1.08
0.32
2.1
2.5
0.7
0.7
%
0.14
106
987
11
143
0.77
0.32
2.3
2.2
485.2
499.0
min
0.32
11
117
157
1667
0.94
0.31
2.3
2.6
164.8
106.5
ng/l
0.71
139
1478
36
314
1.15
0.31
3.1
2.5
0.2
0.2
e9/l
0.29
31
261
19
156
1.22
0.31
2.4
2.2
197.3
185.4
e6/l
0.06
11
87
195
1849
1.06
0.30
2.4
2.5
67.0
72.6
e9/l
1.70
146
1335
303
2907
1.05
0.30
3.9
4.1
0.2
0.2
%
0.13
59
630
39
343
1.14
0.30
2.8
2.1
8.6
12.6
%
2.45
19
186
12
93
1.29
0.30
1.3
1.2
—
—
—
0
0
51
458
1.11
0.29
1.4
1.5
—
—
—
0
0
146
1548
0.94
0.28
1.5
1.5
0.4
0.5
nmol/l
1.89
119
1251
41
364
1.13
0.28
1.2
1.2
—
—
—
0
0
12
94
1.28
0.28
1.0
1.0
—
—
—
0
0
60
658
0.91
0.27
1.1
1.1
95.3
15320.5
iu/ml
0.63
16
175
31
354
0.87
0.27
1.2
1.3
—
—
—
0
0
8
64
1.25
0.27
1.3
1.2
91.7
80.5
ng/l
—
8
64
57
518
1.10
0.27
2.7
2.6
80.0
92.5
ug/min
0.10
35
339
183
1741
1.05
0.27
1.2
1.2
—
—
—
0
0
110
1030
1.07
0.27
1.2
1.2
—
—
—
0
0
20
236
0.85
0.26
1.7
1.6
1.9
3.7
nmol/l
0.84
15
183
8
67
1.19
0.26
1.0
1.2
—
—
—
0
0
36
320
1.13
0.25
3.1
2.5
606.5
508.1
e6/l
0.63
31
262
3771
37531
1.02
0.25
14.3
13.0
332.2
331.7
g/l
2.82
3751
37271
40
445
0.90
0.25
1.1
1.0
0.2
1.8
u/ml
0.98
12
118
9
77
1.17
0.24
2.7
1.3
—
—
—
0
0
27
236
1.14
0.24
1.0
1.1
—
—
—
0
0
121
1143
1.06
0.24
1.1
1.1
0.5
1.0
u/ml
1.10
45
463
273
2830
0.96
0.24
1.5
1.4
—
—
—
0
0
52
475
1.10
0.23
1.2
1.3
—
—
—
0
0
86
804
1.07
0.23
1.2
1.2
—
—
—
0
0
20
171
1.17
0.23
1.1
1.2
—
—
—
0
0
57
524
1.09
0.23
1.2
1.3
0.5
0.5
nmol/l
1.60
57
510
144
1370
1.05
0.23
2.0
2.2
4.4
5.0
umol/l
0.50
108
1005
17
200
0.85
0.22
1.1
1.0
—
—
—
0
0
34
304
1.12
0.22
1.3
1.6
277.8
280.7
mosm/kgh2o
0.26
29
244
10
79
1.27
0.22
1.6
1.5
—
—
—
0
0
87
927
0.94
0.22
4.6
4.9
1.8
1.7
%
0.40
82
862
14
116
1.21
0.22
1.1
1.3
—
—
—
0
0
47
513
0.92
0.21
1.1
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
324
3145
1.03
0.21
2.2
2.2
4.0
4.1
e9/l
0.71
274
2653
80
750
1.07
0.21
1.1
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
2.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
15.3
—
0
8
0
13
0.00
0.21
0.0
2.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
176
1689
1.04
0.20
1.8
2.0
4.9
5.0
ug/l
0.02
157
1472
442
4313
1.03
0.20
2.6
2.2
24.2
23.7
%
0.41
401
3725
17
198
0.86
0.20
1.2
1.1
—
—
—
0
0
55
594
0.93
0.20
2.6
2.9
24.6
24.5
mmol/l
0.11
50
527
23
261
0.88
0.20
1.3
1.4
4.9
5.0
u/l
0.08
15
230
6
48
1.25
0.20
2.2
2.3
—
—
—
0
0
273
2817
0.97
0.20
1.5
1.4
—
—
—
0
0
41
374
1.10
0.20
1.7
1.4
59.4
66.5
mmol/l
0.63
36
304
25
221
1.13
0.20
1.6
1.4
—
—
—
0
0
288
2794
1.03
0.20
3.6
3.8
1.1
0.6
%
0.28
51
504
97
1025
0.95
0.20
3.4
2.8
—
—
—
0
0
313
3041
1.03
0.20
3.3
3.4
—
—
—
0
0
97
1024
0.95
0.19
1.0
1.1
0.8
4.9
u/ml
3.99
30
378
11
133
0.83
0.19
1.4
1.5
—
—
—
0
0
11
133
0.83
0.19
1.5
1.5
—
—
—
0
0
14
118
1.19
0.19
2.7
2.1
—
—
—
0
0
312
3035
1.03
0.18
3.8
4.0
0.9
0.9
%
0.04
62
682
6
53
1.13
0.18
1.0
1.4
—
263.1
—
0
7
106
1114
0.95
0.18
1.4
1.2
838.6
1046.7
titre
—
7
58
36
328
1.10
0.18
1.3
1.2
—
—
—
0
0
14
164
0.85
0.18
1.1
1.1
—
—
—
0
0
194
2009
0.96
0.18
1.1
1.1
—
—
—
0
0
7
58
1.21
0.18
1.1
1.1
—
—
—
0
0
233
2259
1.03
0.17
6.1
7.1
96.6
96.3
%
0.51
224
2170
11
131
0.84
0.17
1.0
1.1
5.1
5.5
nmol/l
0.18
11
123
126
1208
1.04
0.17
6.3
8.0
24.3
24.2
mmol/l
0.27
117
1141
5
70
0.71
0.16
2.0
1.9
—
—
—
0
0
8
68
1.18
0.16
1.3
1.5
—
—
—
0
0
282
2895
0.97
0.16
1.5
1.5
—
—
—
0
0
29
319
0.91
0.16
3.2
3.3
—
—
—
0
0
87
915
0.95
0.16
3.6
2.7
24.8
24.7
mmol/l
0.11
82
857
60
564
1.06
0.16
1.4
1.5
8.1
11.3
mmol/l
—
10
70
96
916
1.05
0.16
1.3
1.3
—
—
—
0
0
37
341
1.09
0.15
1.5
1.4
—
—
—
0
0
337
3447
0.98
0.15
1.4
1.4
—
—
—
0
0
418
4263
0.98
0.15
1.7
1.7
—
—
—
0
0
417
4252
0.98
0.15
1.4
1.4
—
—
—
0
0
14
121
1.16
0.15
1.0
1.0
551.1
819.5
ng/l
—
9
88
14
121
1.16
0.15
1.0
1.0
287.2
332.2
ng/l
—
9
90
33
358
0.92
0.14
1.5
1.6
90.9
90.9
%
0.01
33
353
137
1419
0.96
0.14
5.1
4.8
—
—
—
0
0
37
343
1.08
0.14
1.1
1.1
—
—
—
0
0
10
84
1.19
0.14
1.0
1.1
—
—
—
0
0
72
685
1.05
0.14
4.7
3.9
3.7
3.8
mmol/l
0.12
65
639
270
2638
1.02
0.13
5.8
6.6
1.1
0.9
mmol/l
0.46
202
2003
42
449
0.93
0.13
1.0
1.0
0.4
0.9
u/ml
0.79
11
94
38
407
0.93
0.13
2.2
2.4
—
—
—
0
0
49
519
0.94
0.12
1.1
1.1
—
—
—
0
0
38
355
1.07
0.12
1.2
1.2
—
—
—
0
0
185
1802
1.03
0.12
1.2
1.2
13.6
11.4
u/l
1.19
161
1498
1401
14114
0.99
0.12
1.6
1.7
—
—
—
0
0
164
1597
1.03
0.11
1.1
1.1
2.6
5.2
u/ml
1.26
32
258
45
425
1.06
0.11
1.9
2.6
1.5
1.4
%
0.12
36
337
89
857
1.04
0.11
1.3
1.3
111.9
108.2
u/ml
0.15
19
191
125
1212
1.03
0.11
1.1
1.1
4.9
5.3
u/ml
0.14
58
626
27
250
1.08
0.11
1.0
1.1
—
—
—
0
0
24
221
1.09
0.11
3.0
2.8
—
—
—
0
0
92
953
0.96
0.10
1.0
1.1
1.4
3.9
u/ml
3.89
32
384
76
731
1.04
0.10
2.8
2.2
—
—
—
0
0
67
643
1.04
0.10
1.3
1.3
—
—
—
0
0
121
1245
0.97
0.10
7.9
8.5
—
—
—
0
0
51
486
1.05
0.10
1.7
1.7
—
—
—
0
0
12
106
1.13
0.09
1.1
1.2
—
—
—
0
0
39
369
1.06
0.09
1.1
1.1
1.1
1.0
ratio
1.03
16
132
381
3757
1.02
0.09
1.2
1.3
—
—
—
0
0
16
145
1.10
0.09
1.4
1.2
30.8
35.8
mmol/l
0.44
16
133
90
872
1.03
0.09
1.2
1.2
—
—
—
0
0
6
54
1.11
0.09
1.3
2.5
—
—
—
0
0
94
912
1.03
0.09
1.1
1.1
2.1
3.4
u/ml
1.19
55
508
148
1513
0.98
0.08
1.2
1.2
—
—
—
0
0
267
2629
1.02
0.08
5.8
6.6
13.7
13.7
kpa
0.00
254
2516
267
2629
1.02
0.08
5.8
6.6
5.1
5.0
kpa
0.37
255
2521
5
61
0.82
0.08
1.0
1.7
2.5
3.1
mmol/l
—
5
56
37
389
0.95
0.08
1.2
1.3
—
—
—
0
0
7
65
1.08
0.08
1.0
1.5
—
20.0
—
0
5
7
66
1.06
0.08
1.3
1.2
21.2
72.3
mu/l
—
7
52
117
1142
1.03
0.08
1.1
1.1
0.5
1.3
u/ml
1.31
24
278
7
67
1.04
0.08
1.0
1.1
—
—
—
0
0
7
68
1.03
0.07
1.3
1.3
—
—
—
0
0
730
7357
0.99
0.07
3.6
3.2
523.6
495.7
mg/l
0.05
448
4406
8
77
1.04
0.07
1.0
7.2
—
—
—
0
0
8
77
1.04
0.07
1.0
1.2
534.6
291.2
pmol/l
—
8
55
7
80
0.87
0.07
4.6
2.1
—
—
—
0
0
7
82
0.85
0.07
1.1
1.1
—
—
—
0
0
109
1115
0.98
0.07
1.4
1.3
86.7
159.2
titre
—
9
105
45
433
1.04
0.06
1.0
1.1
—
—
—
0
0
15
138
1.09
0.06
1.0
1.1
—
—
—
0
0
71
730
0.97
0.06
1.3
1.3
1.1
1.4
nmol/l
1.84
64
603
162
1594
1.02
0.06
2.3
2.2
—
—
—
0
0
28
266
1.05
0.06
1.6
1.7
34.7
41.7
%
0.43
17
145
17
182
0.93
0.05
1.0
1.2
—
—
—
0
0
10
90
1.11
0.05
1.2
1.1
—
—
—
0
0
133
1352
0.98
0.05
1.2
1.1
2.0
1.3
u/ml
0.38
48
499
31
298
1.04
0.04
1.2
1.4
10.2
9.9
umol/l
0.09
31
284
10
91
1.10
0.04
1.1
1.1
—
—
—
0
0
74
725
1.02
0.04
3.1
3.3
15.8
22.5
mg/l
1.50
34
444
34
352
0.97
0.04
1.4
1.2
51.4
19.4
u/l
0.41
29
309
11
101
1.09
0.04
2.4
1.4
—
—
—
0
0
11
101
1.09
0.04
2.7
2.1
3.0
3.2
ug/l
0.11
11
90
16
170
0.94
0.04
2.9
2.1
1.8
1.1
ug/l
0.45
16
161
26
271
0.96
0.04
1.2
1.3
—
—
—
0
0
84
825
1.02
0.04
1.1
1.1
0.0
0.3
u/ml
0.98
17
162
763
7662
1.00
0.04
4.0
3.9
12.1
9.8
mg/mmol
0.49
455
4701
29
279
1.04
0.04
2.1
3.1
—
—
—
0
0
21
200
1.05
0.03
1.2
1.6
123.3
127.6
nmol/l
0.21
21
200
12
129
0.93
0.03
1.3
1.4
—
—
—
0
0
835
8380
1.00
0.03
2.8
2.8
—
—
—
0
0
195
1933
1.01
0.03
2.7
2.4
66.5
67.5
g/l
0.97
176
1795
19
182
1.04
0.02
1.6
1.7
—
—
—
0
0
13
137
0.95
0.01
2.8
2.0
—
—
—
0
0
141
1420
0.99
0.01
7.4
6.7
24.5
24.4
mmol/l
0.21
133
1320
16
167
0.96
0.01
1.1
1.1
—
—
—
0
0
351
3499
1.00
0.01
1.3
1.3
127.8
186.5
u/ml
0.93
321
3251
27
263
1.03
0.01
4.9
7.3
11.9
11.3
mg/l
0.26
27
248
14
146
0.96
0.00
1.2
1.2
—
0.2
g/l
—
0
8
26
266
0.98
0.00
3.2
2.4
—
—
—
0
0
38
386
0.98
0.00
2.8
1.7
—
—
—
0
0
18
182
0.99
0.00
1.0
1.2
—
—
—
0
0
10
104
0.96
0.00
1.0
1.0
—
—
—
0
0
14
144
0.97
0.00
1.3
1.1
16.8
10.1
%
—
5
19
16
156
1.03
0.00
1.6
1.6
4.4
5.8
%
—
7
28
18
184
0.98
0.00
1.4
1.2
—
—
—
0
0
42
416
1.01
0.00
1.0
1.0
0.3
0.3
u/ml
—
5
54
14
139
1.01
0.00
1.1
1.3
—
—
—
0
0
6
59
1.02
0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
573.6
—
0
5
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
5.0
—
11.3
—
0
7
0
5
0.00
0.00
0.0
1.0
—
7.7
—
0
5
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
0.2
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
31
310
1.00
0.00
1.1
1.1
1396.3
1526.4
miu/ml
0.28
31
310
9
93
0.97
0.00
1.0
1.1
—
—
—
0
0
9
94
0.96
0.00
1.0
1.1
—
200.0
—
0
8
9
93
0.97
0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
0.00
1.0
1.1
—
—
—
0
0
7
69
1.01
0.00
1.6
1.7
—
—
—
0
0
5
57
0.88
0.00
1.2
1.6
—
—
—
0
0
5
52
0.96
0.00
1.8
7.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_CERVICAL_LSIL and mortality.

Females

Parameter HR [95% CI] p-value
N14_CERVICAL_LSIL 0.988 [0.86, 1.13] 0.866
Birth year 0.997 [0.99, 1.01] 0.519

During the follow-up period (1.1.1998 — 31.12.2019), 701 out of 24340 females with N14_CERVICAL_LSIL died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_CERVICAL_LSIL.

N-year risk Females Males
1 0.097% No data
5 0.671% No data
10 1.573% No data
15 3.058% No data
20 5.365% No data

Relationships between endpoints

Index endpoint: N14_CERVICAL_LSIL – LSIL lesion of the cervix uteri

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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