LSIL lesion of the cervix uteri, vagina or vulva

N14_FEMALE_GENITAL_LSIL

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N87.0, N89.0, N90.0
  • Hospital discharge: ICD-9 6221A|0781C
  • Cause of death: ICD-10 N87.0, N89.0, N90.0
  • Cause of death: ICD-9 6221A|0781C

2 out of 7 registries used, show all original rules.

6446

4. Check minimum number of events

None

6446

5. Include endpoints

None

6446

6. Filter based on genotype QC (FinnGen only)

6214

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 36492 36492 -
Only index persons 35540 35540 -
Unadjusted period prevalence (%)
Whole population 1.05 1.05 -
Only index persons 1.31 1.31 -
Median age at first event (years)
Whole population - 35.02 -
Only index persons - 34.91 -

-FinnGen-

Key figures

All Female Male
Number of individuals 6214 6214 -
Unadjusted period prevalence (%) 2.20 2.20 -
Median age at first event (years) 36.66 36.66 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
6446
Matched controls
64460
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
23.0
307.7
4485
5831
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
5.8
307.7
676
1275
ULA02
NOMESCO Finland
Kolposcopy
27.5
307.7
4667
5606
N89.0
ICD-10 Finland
Mild vaginal dysplasia
+∞
307.7
572
*
8474
FHL
Coagulation, excision, or biopsy of local change (eg, condyloma, tumor) in operating room or anesthesia
43.0
307.7
196
47
A63.0
ICD-10 Finland
Anogenital (venereal) warts
7.7
307.7
1069
1631
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
18.5
307.7
3415
3692
N90.0
ICD-10 Finland
Mild vulvar dysplasia
4807.0
307.7
458
*
8325
FHL
Coagulation, cryo or laser in anesthesia or operating room
75.3
307.7
183
25
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
10.6
307.7
688
719
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
8.9
307.7
672
830
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
24.4
307.7
249
106
LEB00
NOMESCO Finland
Biopsy of vagina
13.2
307.7
651
543
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
9.5
307.7
3560
7387
0781C
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Viral warts[CONDYLOMA ACCUMINATUM]
+∞
307.7
650
*
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
13.8
307.7
368
282
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
17.4
307.7
2356
2060
N87.1
ICD-10 Finland
Moderate cervical dysplasia
9.0
307.7
840
1057
LDA10
NOMESCO Finland
Curettage of cervix uteri
11.8
307.7
1766
2000
N87.0
ICD-10 Finland
Mild cervical dysplasia
5801.5
307.7
4958
37
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
6.5
291.5
499
823
8411
FHL
Local change laser, coagulation, biopsy or removal
47.2
213.8
125
27
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
40.5
209.5
127
32
6221A
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI LEVIS]
+∞
199.0
190
*
ZXC00
NOMESCO Finland
Use of diathermy
12.4
189.8
189
157
8326
FHL
Batch conization
18.0
185.7
150
85
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
22.2
127.7
94
43
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
43.4
122.4
73
17
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
19.5
120.8
94
49
R87.0
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of enzymes
28.3
120.4
81
29
N87.9
ICD-10 Finland
Dysplasia of cervix uteri, unspecified
10.3
115.8
130
129
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
14.5
115.2
104
73
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
21.5
114.1
85
40
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.8
111.6
3146
22352
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
8.0
111.0
151
192
G01AA10
ATC
clindamycin; vaginal
1.9
106.2
1703
10128
D06BB10
ATC
imiquimod; topical
3.0
94.2
440
1532
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
8.5
92.2
119
142
D06BB04
ATC
podophyllotoxin; topical
2.5
91.2
635
2713
X86
ICPC
Abnormal cervix smear
4.6
83.2
200
444
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
5.0
70.0
152
310
LDB10
NOMESCO Finland
Cryotherapy of cervix uteri
9.3
67.5
81
88
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
18.1
64.6
52
29
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
9.3
61.0
73
79
C539, 6666, 0
ICD-O-3
3.9
51.5
151
390
8111
FHL
Taking a biopsy from the mouth of the uterus at the operating room or under anesthesia (vulvabiopsia 8474, vaginabiopsia 8411)
15.7
48.6
42
27
LCA06
NOMESCO Finland
Biopsy of endometrium
1.7
48.5
1133
7302
1390
FHL
Colposcopy
13.3
47.6
45
34
J02AC01
ATC
fluconazole; systemic
1.5
46.5
3434
28291
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
46.3
2118
15897
P01AB01
ATC
metronidazole; oral, rectal
1.5
45.0
2887
23105
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.6
42.6
1151
7670
6221B
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI MODERATA]
12.6
40.9
40
32
Z3231
NOMESCO Finland
Registered nurse
1.5
38.6
1486
10690
Z3232
NOMESCO Finland
Midwife
1.6
37.2
982
6485
Z2221
NOMESCO Finland
Medical doctor
1.4
36.3
1820
13759
N93.0
ICD-10 Finland
Postcoital and contact bleeding
3.4
33.4
123
371
X23
ICPC
Fear sexually transm dis female
1.8
33.3
562
3293
R87.9
ICD-10 Finland
Abnormal findings in specimens from female genital organs, unspecified abnormal finding
6.5
33.2
54
84
N72
ICD-10 Finland
Inflammatory disease of cervix uteri
3.9
32.1
93
239
G01AF01
ATC
metronidazole; vaginal
1.6
31.3
757
4882
LFC00
NOMESCO Finland
Partial excision of vulva
7.5
30.9
44
59
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.4
30.1
1675
12827
N76.0
ICD-10 Finland
Acute vaginitis
1.6
29.7
710
4561
N87
ICD-10 Finland
Dysplasia of cervix uteri
8.6
29.2
37
43
LDC00
NOMESCO Finland
Conisation of cervix uteri using knife
11.2
28.4
30
27
R2110
NOMESCO Finland
Giving the first information
1.7
27.1
546
3354
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
27.1
1947
15497
TLC02
NOMESCO Finland
Simple extraction of IUD
1.8
26.7
462
2723
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
1.7
24.9
489
2982
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1.5
24.7
886
6218
R87.2
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of other drugs, medicaments and biological substances
7.1
24.1
36
51
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
23.8
350
1965
N07BA03
ATC
varenicline; oral
1.9
22.3
306
1682
SPAT1193
SPAT
Pap smear
1.4
22.1
999
7322
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.4
21.3
1016
7513
M03BX02
ATC
tizanidine; oral
1.3
21.2
4061
36601
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
20.6
4762
43911
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
20.4
4502
41211
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
20.4
2958
25681
N02AX02
ATC
tramadol; systemic, rectal
1.3
20.1
2126
17714
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
2.0
19.9
218
1112
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
19.8
2061
17129
ZXC10
NOMESCO Finland
Use of laser
2.5
19.8
122
491
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
19.6
1712
13888
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
19.5
339
1999
X92
ICPC
Chlamydia infection genital female
2.4
19.4
130
544
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
19.3
2404
20425
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
19.2
2418
20571
8113
FHL
Fractional scraping
1.9
18.9
258
1415
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
2.2
18.8
163
762
M54.5
ICD-10 Finland
Low back pain
1.3
18.6
2256
19082
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
2.1
18.2
174
845
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.5
18.0
524
3513
7950A
ICD-9 Finland
Nonspecific abnormal histological and immunological findings, Nonspecific abnormal Papanicolaou smear of cervix
16.5
17.8
28
17
X15
ICPC
Vaginal symptom/complaint other
1.7
17.6
354
2172
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
17.4
3671
33055
J01CA08
ATC
pivmecillinam; oral
1.3
17.1
3288
29263
J01DB01
ATC
cefalexin; oral
1.3
16.9
5161
48518
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.5
16.9
633
4467
J05AB01
ATC
aciclovir; systemic
1.3
16.7
1350
10800
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.3
16.6
1712
14145
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
2.2
16.5
141
655
L04AX01
ATC
azathioprine; systemic
1.8
16.4
246
1390
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
16.3
2445
21113
R87.1
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of hormones
6.3
16.3
27
43
SDA03
NOMESCO Finland
Periodontal treatment
1.3
16.2
2567
22301
J01AA02
ATC
doxycycline; systemic
1.3
16.1
4649
43197
SPAT1308
SPAT
Sexual health counselling
1.3
16.1
1162
9142
R87.8
ICD-10 Finland
Abnormal findings in specimens from female genital organs, other abnormal findings
3.7
16.1
50
136
Z01.2
ICD-10 Finland
Dental examination
1.2
15.9
2944
26013
8077/2-C53.1
ICD-O-3
Squamous intraepithelial neoplasia, high grade of exocervix
6.0
15.6
27
45
8339
FHL
Other measure in this category
5.6
15.5
29
52
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.3
15.3
2168
18564
SFA10
NOMESCO Finland
One-surface restoration
1.2
15.0
3436
30976
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.4
14.9
843
6385
N30.0
ICD-10 Finland
Acute cystitis
1.3
14.9
1052
8240
A02BC02
ATC
pantoprazole; systemic
1.2
14.4
3782
34516
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.4
14.2
657
4811
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
3.5
14.1
47
134
UJF32
NOMESCO Finland
Coloscopy
1.3
14.1
1098
8718
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
14.1
2963
26408
SFA20
NOMESCO Finland
Two-surface restoration
1.2
14.0
3766
34400
N02BE01
ATC
paracetamol; systemic, rectal
1.3
13.9
5452
51962
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
13.9
811
6169
Z71.8
ICD-10 Finland
Other specified counselling
1.2
13.9
1945
16596
WX110
NOMESCO Finland
Infiltration anesthesia
1.2
13.8
4478
41691
LCH11
NOMESCO Finland
Pharmacologic abortion
1.5
13.6
397
2660
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
13.5
2495
21905
J01EA01
ATC
trimethoprim; systemic
1.3
13.5
1697
14295
N03AX16
ATC
[U] pregabalin
1.3
13.4
1150
9244
XLA10, ,
NOMESCO Finland
1.5
13.3
367
2429
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
1.7
13.2
249
1504
LDB00
NOMESCO Finland
Excision of lesion of cervix uteri
2.2
13.1
104
471
J01DA01
ATC
[U] cefalexin
1.2
13.1
3744
34302
J05AB11
ATC
valaciclovir; oral
1.3
13.0
832
6418
Z30.0
ICD-10 Finland
General counselling and advice on contraception
1.4
12.9
573
4168
8070/2-C53.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of cervix uteri
3.6
12.8
41
114
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
12.8
2488
21925
ULC02
NOMESCO Finland
Hysteroscopy
1.5
12.6
370
2482
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.3
12.5
1432
11913
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.4
12.5
639
4760
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
12.5
3392
30854
N90.3
ICD-10 Finland
Dysplasia of vulva, unspecified
24.3
12.4
17
7
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
12.4
1300
10705
N90.4
ICD-10 Finland
Leukoplakia of vulva
4.0
12.3
34
85
L04AA01
ATC
[U] ciclosporin
2.5
12.1
74
298
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
5.4
11.8
23
43
N06AX11
ATC
mirtazapine; oral
1.2
11.8
1910
16490
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.3
11.7
1204
9881
N90.9
ICD-10 Finland
Noninflammatory disorder of vulva and perineum, unspecified
2.7
11.7
63
239
N06AB04
ATC
citalopram; systemic
1.3
11.7
1195
9803
L04AD02
ATC
tacrolimus; systemic
3.1
11.7
48
157
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
11.5
4313
40288
K05.31
ICD-10 Finland
Periodontitis pronounced
1.5
11.4
400
2783
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
2.6
11.4
62
236
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.3
11.4
716
5504
D19
ICPC
Teeth/gum symptom/complaint
1.2
11.3
1746
14982
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
11.3
3658
33670
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.5
11.2
414
2909
SCA01
NOMESCO Finland
Preventive oral health care, short
1.2
11.2
1797
15476
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
1.5
11.2
296
1943
N76.6
ICD-10 Finland
Ulceration of vulva
2.4
11.2
74
310
N05CF01
ATC
zopiclone; oral
1.2
11.1
1503
12721
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.4
11.1
519
3808
WZA90
NOMESCO Finland
Other medical or dental certificate
1.3
11.0
1270
10553
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.5
11.0
303
2005
D07AD01
ATC
clobetasol; topical
1.3
11.0
861
6823
K02.1
ICD-10 Finland
Caries of dentine
1.2
10.9
3742
34569
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
10.9
977
7878
A05
ICPC
Feeling ill
1.5
10.8
335
2275
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
10.8
1837
15908
D82
ICPC
Teeth/gum disease
1.2
10.8
2345
20788
WX290
NOMESCO Finland
Other blockage of nerve
1.2
10.5
3098
28196
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
1.7
10.5
194
1168
G01AF04
ATC
miconazole; vaginal
1.5
10.5
352
2431
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
10.4
5858
56788
7020X
ICD-9 Finland
Other dermatoses, Actinic keratosis[DERMATOSES PRAECANCEROSAE ALIAE]
110.2
10.4
11
*
EBA00
NOMESCO Finland
Extraction of tooth
1.2
10.4
1874
16306
D06.1
ICD-10 Finland
Carcinoma in situ: Exocervix
3.9
10.3
29
74
R74
ICPC
Upper respiratory infection acute
1.2
10.2
2369
21089
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
10.2
2333
20740
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.4
10.2
554
4161
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.4
10.2
584
4424
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
1.8
10.2
154
876
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
1.5
10.2
338
2329
ZXE00
NOMESCO Finland
One hour or less
1.2
10.1
2219
19652
R4110
NOMESCO Finland
Physiotherapy
1.2
10.1
1274
10682
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.4
10.1
526
3925
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.3
10.1
840
6705
L29.2
ICD-10 Finland
Pruritus vulvae
1.9
10.0
130
706
8112
FHL
Scraping the cervix
8.4
10.0
21
25
O34.4
ICD-10 Finland
Maternal care for other abnormalities of cervix
4.0
10.0
28
71
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
9.1
10.0
20
22
C07AA05
ATC
propranolol; systemic
1.2
9.9
1292
10870
L82
ICD-10 Finland
Seborrhoeic keratosis
1.3
9.9
772
6111
X14
ICPC
Vaginal discharge
1.6
9.9
199
1226
J01MA02
ATC
ciprofloxacin; systemic
1.2
9.8
1756
15250
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.2
9.7
1293
10902
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
2.2
9.6
81
377
N88.2
ICD-10 Finland
Stricture and stenosis of cervix uteri
4.2
9.6
25
60
M01AH05
ATC
etoricoxib; oral
1.2
9.6
3679
34128
N05BA04
ATC
oxazepam; oral
1.2
9.5
1460
12491
WZC00
NOMESCO Finland
Treatment plan or consultation
1.2
9.5
1957
17217
J01FF01
ATC
clindamycin; systemic
1.2
9.4
1373
11680
M01AB05
ATC
diclofenac; systemic, rectal
1.2
9.3
3860
35991
62191
ICD-8 Finland
Other diseases of cervix, Dysplasia portionis uteri
3.5
9.3
31
89
6221C
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI GRAVIS]
4.4
9.3
23
53
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
4.9
9.3
20
41
P17
ICPC
Tobacco abuse
2.2
9.3
76
350
127
Kela drug reimbursment
Transplant complication
2.4
9.3
61
256
N95.0
ICD-10 Finland
Postmenopausal bleeding
1.4
9.2
435
3194
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
9.2
2276
20322
ZX120
NOMESCO Finland
Intravenous
1.4
9.2
402
2916
Z3226
NOMESCO Finland
Physiotherapist
1.3
9.2
833
6721
WX002
NOMESCO Finland
Sedation and analgesia
1.3
9.2
792
6352
8070/3-C51.9
ICD-O-3
Squamous cell carcinoma, NOS, of vulva, NOS
11.5
9.0
16
14
N76.1
ICD-10 Finland
Subacute and chronic vaginitis
1.6
9.0
207
1317
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
1.3
9.0
525
3987
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.2
9.0
1116
9332
XLD00, ,
SPAT
1.8
9.0
122
674
W11
ICPC
Contraception oral
1.3
8.9
747
5964
M79.6
ICD-10 Finland
Pain in limb
1.2
8.9
2415
21725
C51.11
ICD-10 Finland
Squamous cell carcinoma of the labium minus
12.5
8.8
15
12
ZXA00
NOMESCO Finland
Right side
1.2
8.8
1027
8525
E000006, ,
ATC
1.4
8.8
341
2421
J01FA10
ATC
azithromycin; systemic
1.2
8.7
3773
35209
N30
ICD-10 Finland
Cystitis
1.3
8.7
566
4368
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
8.7
1615
14048
KMAK, ,
NOMESCO Finland
1.2
8.6
3374
31219
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.2
8.6
1477
12752
M25.5
ICD-10 Finland
Pain in joint
1.2
8.6
1943
17198
R51.80
ICD-10 Finland
Headache
1.2
8.5
1008
8387
LEB10
NOMESCO Finland
Excision of lesion of vagina
2.8
8.5
41
148
6230A
ICD-9 Finland
Noninflammatory disorders of vagina, Dysplasia of vagina[DYSPLASIA VAGINAE LEVIS]
20.0
8.5
12
6
SFA00
NOMESCO Finland
Small restoration
1.3
8.3
744
5989
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.5
8.3
227
1504
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.2
8.3
1204
10224
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.2
8.2
1045
8756
M54.4
ICD-10 Finland
Lumbago with sciatica
1.2
8.2
997
8315
Z01.8
ICD-10 Finland
Other specified special examinations
1.2
8.2
1137
9616
H02AB06
ATC
prednisolone; systemic
1.2
8.1
2489
22556
Z00.0
ICD-10 Finland
General medical examination
1.2
8.1
888
7321
A02BC03
ATC
lansoprazole; oral
1.2
8.0
1307
11227
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
1.6
8.0
164
1018
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
1.5
7.9
246
1674
SFA30
NOMESCO Finland
Three-surface restoration
1.2
7.9
2283
20590
H02AB07
ATC
prednisone; oral
1.3
7.8
621
4923
P01BA02
ATC
hydroxychloroquine; oral
1.3
7.8
438
3308
R53
ICD-10 Finland
Malaise and fatigue
1.2
7.8
1329
11453
M03BC01
ATC
orphenadrine (citrate); systemic
1.2
7.8
1395
12076
N05AH04
ATC
quetiapine; oral
1.2
7.8
996
8347
A11CC03
ATC
alfacalcidol; systemic
2.1
7.8
73
356
Z30.2
ICD-10 Finland
Sterilization
1.3
7.8
754
6129
A12AA04
ATC
calcium carbonate; oral
2.5
7.7
46
185
N86
ICD-10 Finland
Erosion and ectropion of cervix uteri
2.9
7.6
35
123
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
3.0
7.6
32
107
A06AC01
ATC
ispaghula (psylla seeds); oral
1.2
7.6
1231
10559
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.2
7.6
957
8007
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
1.6
7.6
167
1055
F41.1
ICD-10 Finland
Generalized anxiety disorder
1.4
7.5
376
2792
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.3
7.5
736
5990
N06AX16
ATC
venlafaxine; oral
1.2
7.5
907
7558
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
3.1
7.4
30
98
F32.1
ICD-10 Finland
Moderate depressive episode
1.3
7.4
420
3179
A03
ICPC
Fever
1.2
7.4
1051
8898
R05
ICPC
Cough
1.2
7.4
1317
11397
K50.8
ICD-10 Finland
Other Crohn disease
1.9
7.3
83
433
J02AC02
ATC
itraconazole; systemic
1.2
7.3
980
8245
S22.3
ICD-10 Finland
Fracture of rib
1.5
7.3
219
1481
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.6
7.3
41
160
G01AF05
ATC
econazole; vaginal
1.3
7.3
577
4572
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.3
7.3
758
6207
K03.64
ICD-10 Finland
Dental calculus supragingival
1.2
7.3
2022
18144
P01
ICPC
Feeling anxious/nervous/tense
1.2
7.3
898
7497
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.2
7.2
1464
12804
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.3
7.2
488
3789
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.2
7.2
996
8409
N90.8
ICD-10 Finland
Other specified noninflammatory disorders of vulva and perineum
2.0
7.2
78
402
Z2446
NOMESCO Finland
Social worker
1.4
7.2
296
2129
WX408
NOMESCO Finland
General anesthesy, balanced
1.2
7.2
1213
10442
N06AB10
ATC
escitalopram; oral
1.2
7.1
1380
12019
N03AX12
ATC
[U] gabapentin; oral
1.2
7.1
761
6253
G44.2
ICD-10 Finland
Tension-type headache
1.2
7.1
883
7374
ZXE20
NOMESCO Finland
More than three and less than five hours
1.3
7.1
479
3718
S18
ICPC
Laceration/cut
1.2
7.1
2018
18137
TK800
NOMESCO Finland
Hemodialysis
2.2
7.1
56
256
K05.30
ICD-10 Finland
Periodontitis complex
1.3
7.0
588
4693
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.2
7.0
54
244
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
3.3
7.0
25
76
L03
ICPC
Low back symptom/complaint
1.2
6.9
1566
13815
SPAT1283
SPAT
Restricted health certificate
1.2
6.9
1381
12056
8511
FHL
Cervical dilation and drainage with suction
1.5
6.9
216
1475
X59
ICD-10 Finland
Exposure to unspecified factor
1.2
6.9
844
7036
N77.1*A60.0
ICD-10 Finland
Vaginitis, vulvitis and vulvovaginitis in herpesviral [herpes simplex] infection
2.2
6.9
54
246
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.2
6.9
54
246
T36
ICD-10 Finland
Poisoning by systemic antibiotics
1.5
6.9
237
1650
J01CA04
ATC
amoxicillin; systemic
1.2
6.8
5174
49889
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.3
6.8
678
5524
8070/2-C51.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of vulva, NOS
40.1
6.8
8
*
SPAT1192
SPAT
Gynaecological examination
1.2
6.7
863
7228
R87
ICD-10 Finland
Abnormal findings in specimens from female genital organs
3.6
6.7
21
58
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.3
6.7
404
3085
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.2
6.7
1740
15523
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.3
6.6
418
3216
E0000UV, ,
ATC
1.2
6.6
2390
21834
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.3
6.6
469
3667
K30
ICD-10 Finland
Functional dyspepsia
1.3
6.5
614
4970
R87.4
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal immunological findings
8.7
6.5
13
15
R07.0
ICD-10 Finland
Pain in throat
1.3
6.5
438
3399
EB1VA, ,
NOMESCO Finland
1.3
6.5
653
5328
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
1.8
6.5
91
510
N06AX21
ATC
duloxetine; oral
1.2
6.5
676
5538
N06AB06
ATC
sertraline; oral
1.2
6.5
686
5632
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.3
6.5
475
3731
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.3
6.5
414
3192
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
2.1
6.4
60
293
Z94.4
ICD-10 Finland
Liver transplant status
3.9
6.4
18
46
4044, ,
NOMESCO Finland
7.4
6.4
14
19
R42
ICD-10 Finland
Dizziness and giddiness
1.2
6.4
995
8493
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.2
6.4
890
7517
L04AX03
ATC
methotrexate; systemic
1.3
6.4
475
3738
L04AA06
ATC
mycophenolic acid; systemic
1.9
6.4
75
398
M01AH01
ATC
celecoxib; oral
1.2
6.4
775
6458
G03CA04
ATC
estriol; systemic, vaginal
1.5
6.3
191
1296
D06BB03
ATC
aciclovir; topical
1.4
6.3
254
1820
SPAT1307
SPAT
Psychosocial counselling and guidance
1.3
6.3
402
3097
R07.4
ICD-10 Finland
Chest pain, unspecified
1.2
6.3
1087
9367
JAH01
NOMESCO Finland
Laparoscopy
1.4
6.3
286
2094
M01AE02
ATC
naproxen; oral, rectal
1.1
6.3
3448
32364
SDA12
NOMESCO Finland
Treatment of complicated periodontal disease
1.9
6.3
73
386
TK810
NOMESCO Finland
Hemofiltration
3.8
6.2
18
47
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.3
6.2
527
4214
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
1.5
6.2
175
1171
W12
ICPC
Contraception intrauterine
1.2
6.2
909
7713
SPAT1312
SPAT
General health counselling
1.2
6.2
1689
15101
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.3
6.2
568
4586
X91
ICPC
Condylomata acuminata female
2.9
6.2
28
98
Z94.0
ICD-10 Finland
Kidney transplant status
2.4
6.2
38
156
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.2
6.2
1329
11667
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
1.7
6.2
103
608
B37.3
ICD-10 Finland
Candidiasis of vulva and vagina
1.6
6.2
131
823
XF400
NOMESCO Finland
ECG with 12 standard connections
1.3
6.2
476
3764
A07EC02
ATC
mesalazine; oral, rectal
1.4
6.2
249
1787
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.2
6.1
734
6102
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
1.5
6.1
205
1420
VALMI, ,
NOMESCO Finland
1.2
6.1
1435
12679
09992
ICD-8 Finland
Other veneral disease, Condyloma acuminatum
3.2
6.1
23
72
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
1.3
6.1
421
3279
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.4
6.1
284
2087
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.3
6.1
388
2989
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
1.5
6.1
190
1300
N02AA05
ATC
oxycodone; systemic
1.3
6.1
492
3914
ZXA05
NOMESCO Finland
Left side
1.2
6.1
914
7776
Z72.0
ICD-10 Finland
Tobacco use
1.6
6.1
117
718
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.2
6.0
1089
9416
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.2
6.0
1636
14618

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1203
1413
10.24
307.65
2.4
1.6
—
—
—
0
0
3614
24004
2.15
191.08
2.7
2.0
—
—
—
0
0
650
4139
1.63
28.13
1.3
1.4
—
—
—
0
0
952
6833
1.46
23.64
2.7
2.5
4.53
4.71
e6/l
0.17
517
3475
2075
17317
1.29
19.17
3.9
3.2
67.11
77.38
e6/l
0.56
1391
11344
4038
36574
1.28
19.14
4.4
4.0
1035.34
2074.48
e6/l
0.88
32
397
4423
40531
1.29
19.07
4.2
3.8
10.06
10.21
mm/h
0.42
4192
38182
984
7370
1.40
18.96
2.6
2.4
1.06
1.19
e6/l
0.40
546
3984
1102
8431
1.37
18.62
1.7
1.6
—
—
—
0
0
1553
12522
1.32
18.41
3.0
2.6
—
—
—
0
0
1673
13698
1.30
17.57
3.2
2.8
29.71
73.97
e6/l
2.75
1251
10235
1539
12512
1.30
16.94
3.1
2.7
0.35
0.32
e6/l
0.24
1140
9269
4150
37974
1.26
16.77
4.5
4.0
—
—
—
0
0
2894
25453
1.25
16.50
6.5
6.1
—
—
—
0
0
3059
27075
1.25
16.46
6.5
5.7
0.52
0.53
e9/l
0.66
2740
23993
1625
13349
1.29
16.44
6.8
6.4
—
—
—
0
0
2010
16970
1.27
16.28
2.2
2.0
—
—
—
0
0
1516
12390
1.29
15.87
3.6
3.3
—
—
—
0
0
3057
27139
1.24
15.72
6.5
5.7
0.04
0.04
e9/l
0.57
2733
23981
3447
31064
1.24
15.19
9.0
8.5
3.92
3.93
e9/l
0.17
3053
27472
4223
38908
1.25
15.15
7.5
6.7
71.74
73.18
u/l
1.88
3980
36830
3145
28175
1.23
14.27
6.6
5.9
0.18
0.18
e9/l
0.77
2884
25294
3139
28130
1.23
14.15
6.5
5.7
1.98
1.96
e9/l
0.29
2912
25474
2854
25407
1.22
13.48
6.5
5.7
2.75
2.77
%
0.28
2684
23914
2860
25544
1.22
12.84
6.7
6.0
7.94
7.93
%
0.09
2694
24108
2123
18415
1.23
12.72
1.8
1.8
98.88
99.59
pmol/l
0.28
1133
9613
2750
24483
1.21
12.71
6.6
5.8
0.69
0.69
%
0.27
2577
22915
515
3685
1.43
12.68
1.3
1.2
—
—
—
0
0
3050
27441
1.21
12.62
3.5
3.3
0.00
0.00
estimate
0.18
603
5614
2271
19900
1.22
12.17
5.4
4.8
1.22
1.22
mmol/l
0.27
2109
18345
3071
27729
1.21
11.99
3.5
3.3
0.00
0.00
estimate
0.04
570
5384
3051
27548
1.20
11.87
4.8
4.5
0.00
0.00
estimate
0.42
579
5459
2949
26574
1.20
11.63
6.5
5.7
30.10
29.63
%
1.85
2787
25149
2914
26231
1.20
11.62
6.4
5.6
55.98
56.47
%
1.69
2752
24799
2670
23911
1.20
11.07
8.5
8.1
0.00
0.00
e9/l
0.62
2217
19661
1449
12222
1.24
11.01
3.9
3.2
96.40
98.32
%
2.55
1407
11835
1053
8569
1.27
10.92
2.5
2.3
110.62
99.92
ug/g
0.45
842
6716
614
4670
1.35
10.45
2.3
2.3
41.39
35.86
u/l
0.37
527
3973
263
1726
1.55
9.99
1.2
1.1
—
—
—
0
0
2481
22281
1.18
9.49
6.1
5.5
1.22
1.22
mmol/l
0.68
2180
18968
2760
25056
1.18
9.18
5.7
5.3
9.35
9.60
umol/l
0.99
2630
23630
5560
53694
1.26
8.95
11.7
10.5
139.57
139.59
mmol/l
0.29
5438
52335
1801
15814
1.19
8.76
2.8
2.6
—
—
—
0
0
5572
53857
1.26
8.68
11.9
10.6
3.90
3.90
mmol/l
0.47
5438
52352
739
5921
1.28
8.59
1.7
1.6
—
—
—
0
0
878
7211
1.25
8.28
1.2
1.2
—
—
—
0
0
1737
15302
1.18
8.00
1.3
1.3
1.52
1.48
u/ml
0.04
544
4467
5723
55576
1.27
7.97
12.3
10.6
18.42
18.66
mg/l
0.23
4479
42857
1056
8889
1.22
7.91
3.0
2.6
498.78
517.76
mosm/kgh2o
2.00
916
7597
1532
13367
1.19
7.86
4.4
3.5
7.40
7.40
ph
0.35
241
2600
2457
22299
1.16
7.78
3.3
3.1
5.92
5.95
ph
0.25
261
2435
1474
12835
1.19
7.72
1.5
1.4
2.17
2.13
g/l
0.55
889
8206
1145
9740
1.21
7.71
1.5
1.5
22.12
21.29
nmol/l
0.77
1019
8560
1124
9578
1.21
7.41
2.7
2.3
7.57
8.61
e6/l
1.14
1000
8512
2180
19662
1.16
7.38
4.9
4.2
36.69
36.60
g/l
0.35
2057
18387
325
2363
1.40
7.37
1.7
1.7
—
—
—
0
0
3622
33912
1.16
7.37
3.0
2.9
—
—
—
0
0
6012
58826
1.33
7.35
10.8
10.0
—
—
—
0
0
340
2498
1.38
7.25
1.9
1.7
—
—
—
0
0
691
5640
1.25
6.86
1.4
1.3
—
—
—
0
0
2589
23750
1.15
6.81
2.4
2.3
77.02
3776.67
nmol/l
0.50
2395
22155
1735
15457
1.17
6.77
2.4
2.4
54.51
58.18
u/l
1.89
1630
14346
1333
11624
1.19
6.76
3.9
3.6
1.02
1.02
kg/l
0.12
177
1745
202
1374
1.49
6.61
3.8
2.5
—
—
—
0
0
2019
18226
1.16
6.58
3.5
3.0
30.92
29.91
u/l
0.18
1935
17426
950
8063
1.21
6.48
2.4
2.5
2.42
2.43
mmol/l
0.49
796
7057
38
153
2.49
6.41
3.4
2.5
—
—
—
0
0
5942
58168
1.28
6.31
10.0
8.8
23.58
23.89
u/l
0.47
5802
56573
1615
14377
1.16
6.29
3.8
3.6
0.00
0.00
estimate
0.11
584
5397
1424
12562
1.17
6.22
2.1
1.9
—
—
—
0
0
201
1384
1.47
6.21
2.4
2.2
—
—
—
0
0
4822
46347
1.16
6.13
4.5
4.4
37.28
37.72
mmol/mol
3.27
4550
43797
661
5445
1.24
6.04
1.5
1.4
—
—
—
0
0
1051
9062
1.19
6.02
1.4
1.4
557.94
593.18
titre
0.29
253
1888
1875
16948
1.15
5.87
2.2
2.0
—
—
—
0
0
52
250
2.09
5.85
3.2
2.7
42.66
47.22
%
1.01
23
164
5498
53461
1.19
5.80
5.3
5.1
2.14
1.93
mu/l
0.20
5219
50712
347
2669
1.32
5.54
1.1
1.1
40.10
3.12
u/ml
—
8
34
434
3442
1.28
5.51
2.4
2.7
—
—
—
0
0
1433
12759
1.16
5.47
1.9
2.0
114.18
140.51
u/l
2.75
1373
12085
602
4963
1.23
5.46
6.8
4.7
1.05
1.04
mmol/l
0.79
561
4630
1284
11339
1.17
5.46
1.3
1.3
9.20
9.59
u/ml
0.09
538
4841
368
2860
1.30
5.46
1.4
1.3
1.87
1.19
u/ml
0.31
34
241
4929
47576
1.15
5.43
4.5
4.4
14.36
14.35
pmol/l
0.05
4650
44764
797
6779
1.20
5.29
3.2
3.0
0.82
0.82
mmol/l
0.91
745
6381
1333
11836
1.16
5.26
1.4
1.3
26.32
28.34
iu/ml
0.21
445
3871
1607
14471
1.15
5.21
1.7
1.7
—
—
—
0
0
746
6316
1.20
5.20
1.9
1.8
—
—
—
0
0
1422
12712
1.15
5.10
1.7
1.7
0.88
0.87
mg/l
0.03
1038
9499
680
5720
1.21
5.07
2.9
2.3
5.29
6.12
umol/l
1.28
586
4809
64
350
1.84
5.04
2.7
2.9
665.72
839.92
e6/l
2.29
64
342
256
1917
1.35
4.95
1.4
1.4
27.79
25.37
u/l
0.59
211
1588
5270
51206
1.16
4.95
3.8
3.6
5.60
5.62
mmol/l
0.65
4942
48032
1284
11419
1.16
4.93
1.7
1.7
—
—
—
0
0
865
7464
1.18
4.87
3.0
3.0
250.85
287.97
ng/l
0.14
470
4169
1437
12910
1.15
4.77
1.6
1.6
1.36
1.34
mmol/l
0.19
1267
11218
6301
62378
1.45
4.70
17.8
16.0
30.24
30.03
pg
19.82
6247
61840
6289
62240
1.43
4.67
17.8
16.0
39.81
39.83
%
0.08
6061
59460
259
1961
1.33
4.67
2.7
2.0
0.22
0.23
g/l
1.32
244
1857
6301
62381
1.45
4.67
17.8
16.0
90.84
90.31
fl
19.11
6247
61845
493
4050
1.24
4.65
2.9
2.6
10.32
10.44
g/l
0.32
460
3711
73
426
1.72
4.65
3.9
2.7
—
—
—
0
0
6301
62388
1.44
4.59
17.9
16.0
4.42
4.45
e12/l
5.52
6171
61192
6301
62391
1.44
4.55
17.9
16.1
6.68
6.65
e9/l
0.34
6174
61146
6301
62411
1.43
4.33
17.9
16.1
133.14
132.94
g/l
0.75
6252
61863
5461
53321
1.16
4.29
3.8
3.6
4.85
4.87
mmol/l
0.93
5219
50778
5241
51025
1.15
4.29
3.4
3.3
1.19
1.20
mmol/l
0.48
4956
48273
2934
27653
1.11
4.26
4.2
3.8
6.27
6.33
mmol/l
0.61
2709
25045
66
386
1.72
4.21
1.1
1.2
362.86
196.43
titre
0.60
14
84
66
386
1.72
4.21
1.1
1.2
26.00
98.75
titre
—
5
8
356
2854
1.26
4.20
1.4
1.3
—
—
—
0
0
1785
16395
1.12
4.09
3.1
3.1
2.34
2.35
mmol/l
1.82
1592
14843
348
2794
1.26
4.07
8.7
6.6
8.15
7.49
mmol/l
1.12
333
2682
170
1235
1.39
4.04
1.6
1.6
—
—
—
0
0
6292
62337
1.39
4.00
17.9
16.0
269.64
269.06
e9/l
0.32
6175
61220
820
7164
1.17
3.97
1.2
1.2
—
—
—
0
0
261
2032
1.30
3.92
2.7
1.9
1.12
1.17
g/l
2.00
248
1930
685
5906
1.18
3.91
1.5
1.4
—
—
—
0
0
185
1371
1.36
3.91
1.4
1.4
325.53
306.14
ug/g
0.66
117
712
5508
53884
1.15
3.90
4.0
3.9
2.90
2.92
mmol/l
0.83
5216
51049
256
1994
1.30
3.83
1.3
1.3
38.01
33.19
u/ml
0.17
29
149
345
2794
1.25
3.76
7.4
7.7
—
—
—
0
0
365
2976
1.24
3.75
4.0
3.6
5.88
5.82
kpa
0.61
358
2876
47
259
1.82
3.71
4.8
3.1
—
—
—
0
0
362
2953
1.24
3.70
4.0
3.6
1.95
1.85
mmol/l
0.20
313
2500
111
760
1.47
3.69
2.4
1.6
31.30
31.00
iu/ml
—
10
39
553
4713
1.19
3.62
2.5
2.9
31.06
39.30
u/ml
1.16
528
4569
815
7168
1.16
3.61
1.6
1.7
1197.01
1191.73
nmol/l
0.06
668
5594
283
2253
1.27
3.59
2.5
2.6
—
—
—
0
0
13
35
3.72
3.58
5.3
12.5
4.82
5.05
mmol/l
0.08
13
35
5422
53050
1.14
3.56
3.7
3.6
1.57
1.56
mmol/l
0.32
5148
50417
494
4191
1.19
3.42
1.2
1.2
—
—
—
0
0
2798
26505
1.10
3.40
2.4
2.4
—
—
—
0
0
567
4873
1.18
3.38
3.1
3.4
4.51
4.52
pmol/l
0.08
497
4399
5086
49609
1.12
3.37
14.5
12.8
14.39
14.46
%
0.30
5020
48831
3194
30459
1.10
3.35
3.0
2.9
73.07
71.82
ug/l
0.21
3046
28891
423
3546
1.21
3.34
1.1
1.1
368.33
228.22
titre
—
9
93
1401
12833
1.12
3.29
2.2
2.1
2.71
2.74
mg/l
0.13
1215
11069
65
407
1.60
3.28
2.1
2.4
—
—
—
0
0
186
1421
1.32
3.27
2.6
2.4
—
—
—
0
0
643
5603
1.16
3.24
1.4
1.4
—
—
—
0
0
1097
9916
1.13
3.23
3.9
3.7
—
—
—
0
0
817
7246
1.15
3.23
2.6
2.2
14.46
14.21
umol/l
0.45
776
6790
1358
12430
1.12
3.23
3.4
3.1
7.25
7.26
mmol/l
0.05
1174
10855
739
6509
1.15
3.22
2.6
2.2
2.42
2.47
g/l
1.34
682
6045
308
2511
1.24
3.21
2.3
2.0
—
—
—
0
0
381
3177
1.21
3.19
4.0
3.3
80.50
75.48
ng/l
0.49
348
2802
32
164
1.96
3.18
1.3
1.3
—
—
—
0
0
680
5960
1.16
3.17
2.2
2.0
29.35
29.09
s
0.55
662
5761
212
1657
1.29
3.16
8.2
7.4
—
—
—
0
0
155
1161
1.34
3.13
1.5
1.5
11.67
14.99
iu/ml
—
7
27
1657
15352
1.11
3.13
2.7
2.7
22.23
79.81
ng/l
0.70
733
7115
42
237
1.78
3.12
1.8
2.3
153.30
161.25
umol/l
0.06
27
126
514
4415
1.18
3.11
2.3
2.3
24.32
24.64
au/ml
0.02
38
438
144
1068
1.36
3.10
3.8
2.8
1.40
1.34
mg/l
0.52
133
1007
4061
39228
1.10
3.10
3.0
2.8
35.04
34.83
u/l
0.07
3908
37392
269
2172
1.25
3.07
2.2
2.1
—
—
—
0
0
40
224
1.79
3.05
2.2
1.9
9.38
9.90
mg/l
0.21
34
182
207
1622
1.29
3.04
1.1
1.1
—
—
—
0
0
415
3512
1.19
2.99
3.8
3.3
—
—
—
0
0
362
3027
1.21
2.97
1.1
1.1
—
—
—
0
0
161
1224
1.32
2.96
3.1
3.2
228.65
371.87
u/ml
0.27
134
1032
620
5432
1.16
2.92
1.2
1.2
—
—
—
0
0
357
2996
1.20
2.83
2.3
1.9
—
—
—
0
0
33
181
1.83
2.72
1.8
1.6
119.66
141.95
au/ml
—
7
26
292
2415
1.22
2.71
3.1
3.0
4.45
4.65
kpa
0.97
282
2327
471
4069
1.17
2.69
1.2
1.3
32.78
42.12
au/ml
0.53
17
214
23
112
2.06
2.66
4.7
5.3
—
—
—
0
0
387
3295
1.19
2.64
2.3
1.9
—
—
—
0
0
184
1450
1.28
2.63
2.1
1.8
1.42
1.45
g/l
0.14
162
1255
368
3123
1.19
2.61
1.9
1.8
1.27
1.35
g/l
0.72
341
2880
940
8530
1.12
2.59
2.5
2.5
665.09
715.51
ng/l
0.26
780
6984
661
5872
1.14
2.58
2.8
2.3
23.84
23.55
%
0.23
596
5077
383
3266
1.18
2.57
2.2
1.9
—
—
—
0
0
73
500
1.47
2.54
1.6
2.0
26.00
27.29
mg/l
0.08
25
138
384
3287
1.18
2.48
2.2
1.8
—
—
—
0
0
265
2194
1.22
2.46
1.2
1.2
—
—
—
0
0
227
1852
1.23
2.43
1.5
1.6
4.65
7.56
u/ml
—
6
51
618
5492
1.14
2.41
2.1
2.1
383.69
374.21
nmol/l
0.54
580
5053
24
124
1.94
2.39
2.0
1.4
—
—
—
0
0
8
22
3.64
2.36
1.0
1.0
—
—
—
0
0
615
5479
1.14
2.32
2.1
2.1
4146.61
6019.24
u/l
0.69
222
2262
258
2145
1.21
2.32
2.9
2.4
0.25
0.24
e6/l
0.05
242
2044
87
629
1.39
2.29
1.6
1.4
—
—
—
0
0
199
1613
1.24
2.29
1.3
1.3
34.17
40.12
u/ml
0.27
19
177
378
3256
1.17
2.28
2.3
1.8
—
—
—
0
0
218
1786
1.23
2.27
1.4
1.3
17.87
7.13
u/ml
0.75
33
186
221
1814
1.23
2.26
1.4
1.3
18.63
8.34
u/ml
0.94
44
312
1894
17905
1.08
2.19
8.9
8.0
1.11
1.09
inr
0.43
559
5756
713
6436
1.12
2.18
1.3
1.3
27.20
27.65
iu/l
0.13
616
5640
353
3039
1.17
2.16
5.8
6.2
1.11
1.24
mmol/l
2.21
343
2967
51
337
1.52
2.15
3.1
2.6
—
—
—
0
0
9
30
3.00
2.14
1.0
1.7
—
—
—
0
0
111
844
1.32
2.14
3.6
3.3
34.37
41.55
mg/l
0.57
95
687
111
846
1.32
2.11
3.6
3.3
30.46
40.31
mg/l
0.59
96
688
5
10
5.00
2.07
1.0
1.0
—
—
—
0
0
26
147
1.77
2.01
2.0
1.9
1.52
3.97
ug/l
0.68
13
85
383
3345
1.15
1.97
1.4
1.3
209.22
235.72
miu/ml
0.82
195
1723
133
1050
1.27
1.96
1.3
1.2
2.69
3.94
u/ml
1.79
62
424
26
149
1.75
1.94
2.0
1.5
—
—
—
0
0
473
4200
1.14
1.92
3.3
3.5
—
—
—
0
0
119
933
1.28
1.87
1.5
1.5
0.60
0.62
g/l
0.10
95
694
138
1102
1.26
1.87
1.2
1.3
—
—
—
0
0
11
46
2.39
1.85
1.0
1.1
1.53
1.41
umol/24h
0.25
11
46
52
359
1.45
1.82
3.0
2.7
107.41
48.34
mg/l
0.38
33
246
174
1430
1.22
1.82
2.8
2.9
0.29
0.31
g/l
0.12
72
532
99
761
1.31
1.81
1.4
1.3
—
—
—
0
0
1262
11824
1.08
1.81
2.4
2.1
1660.57
2876.27
umol/l
1.12
1131
10666
28
168
1.67
1.80
1.3
1.1
—
—
—
0
0
181
1498
1.21
1.78
1.2
1.2
—
—
—
0
0
144
1164
1.24
1.77
1.3
1.2
320.45
268.67
u/ml
1.25
105
770
172
1420
1.22
1.74
1.4
1.3
1.17
3.59
u/ml
1.39
18
102
23
385
0.60
1.72
7.7
12.3
762.35
848.59
nmol/l
0.36
23
372
2142
22363
0.94
1.72
2.2
2.3
—
—
—
0
0
42
283
1.49
1.68
2.2
2.3
10.11
10.99
%
0.72
42
283
257
2209
1.17
1.67
1.2
1.2
—
—
—
0
0
104
816
1.28
1.66
3.4
3.2
1.01
1.39
ratio
—
8
87
83
632
1.32
1.66
4.0
3.4
—
—
—
0
0
51
361
1.42
1.60
2.4
2.5
53.88
55.68
%
0.30
41
307
440
3940
1.13
1.60
2.6
2.2
0.23
0.22
g/l
0.36
420
3717
25
401
0.62
1.60
8.3
17.5
1277.28
3893.06
nmol/l
0.57
25
387
159
1316
1.21
1.59
1.5
1.4
24647.71
1362.82
e6/l
0.49
125
1071
159
1316
1.21
1.59
1.4
1.3
56.21
23.75
e6/l
0.68
120
1013
113
905
1.25
1.55
1.7
1.5
—
—
—
0
0
81
624
1.30
1.51
1.4
1.5
—
—
—
0
0
287
2511
1.15
1.51
1.6
1.7
—
—
—
0
0
170
1426
1.20
1.50
2.4
2.2
9.55
10.46
mg/l
1.02
164
1342
145
1198
1.22
1.50
1.4
1.3
—
—
—
0
0
185
1567
1.19
1.47
2.6
2.5
3.58
3.61
g/l
0.12
178
1470
81
627
1.30
1.47
1.3
1.4
2.73
2.94
g/l
0.64
62
429
81
628
1.29
1.45
1.3
1.4
0.38
0.37
g/l
0.04
62
429
7
28
2.50
1.45
1.0
1.6
—
—
—
0
0
1670
15938
1.06
1.43
2.8
2.9
—
—
—
0
0
419
3774
1.12
1.41
2.8
2.5
1.74
1.73
%
0.06
376
3361
435
3930
1.11
1.39
3.5
3.6
24.73
24.34
ug/l
0.01
329
2880
12
60
2.00
1.38
1.2
1.3
—
—
—
0
0
24
150
1.60
1.37
1.5
4.9
64.83
1138.91
mg/l
0.49
18
102
51
373
1.37
1.37
1.0
1.1
—
—
—
0
0
16
89
1.80
1.37
1.1
1.1
0.55
0.62
umol/24h
0.38
11
46
33
223
1.48
1.35
1.2
1.1
—
—
—
0
0
248
2169
1.15
1.34
2.8
2.9
—
—
—
0
0
424
3836
1.11
1.33
4.1
4.1
0.02
0.35
%
1.20
95
821
134
1114
1.21
1.33
1.4
1.3
111.71
110.87
u/ml
0.04
28
251
69
531
1.30
1.33
1.1
1.2
—
—
—
0
0
80
629
1.28
1.32
1.3
1.4
7.84
6.43
g/l
1.84
61
431
134
1118
1.20
1.29
2.5
2.1
438.24
502.22
ug/l
0.08
117
994
92
739
1.25
1.28
1.5
1.6
—
—
—
0
0
119
983
1.21
1.28
2.0
1.9
38.90
38.85
g/l
0.03
109
890
85
678
1.26
1.26
1.2
1.2
—
—
—
0
0
417
3788
1.11
1.23
1.4
1.6
287.77
316.75
mu/l
1.17
377
3361
46
338
1.36
1.23
1.1
1.1
4.29
7.97
u/ml
—
9
63
436
3978
1.10
1.19
4.1
4.1
0.11
0.14
%
0.36
104
957
18
109
1.65
1.18
1.1
1.2
361.28
311.26
pmol/l
0.21
18
77
22
335
0.66
1.18
1.9
2.0
—
—
—
0
0
9
169
0.53
1.18
1.1
1.2
—
—
—
0
0
54
410
1.32
1.18
1.1
1.1
—
—
—
0
0
250
2213
1.13
1.17
1.3
1.5
69.29
109.53
pmol/l
2.73
245
2164
1143
10858
1.06
1.14
4.1
3.7
10.86
9.40
mg/mmol
0.41
683
6600
1096
10400
1.06
1.13
3.7
3.2
364.90
490.17
mg/l
0.40
666
6227
142
1209
1.18
1.13
2.6
2.1
2.87
2.87
g/l
0.01
132
1117
232
2050
1.14
1.12
2.2
1.9
21.00
20.67
s
0.41
201
1716
81
653
1.24
1.12
4.0
5.6
379.32
374.40
umol/l
0.10
66
560
57
440
1.30
1.12
1.2
1.2
—
—
—
0
0
106
880
1.21
1.11
2.4
2.6
—
—
—
0
0
44
327
1.35
1.11
3.0
3.2
0.76
0.79
nmol/l
0.22
35
244
53
406
1.31
1.10
3.0
2.6
0.21
0.21
e9/l
0.16
47
336
11
59
1.87
1.07
1.1
1.1
—
—
—
0
0
38
278
1.37
1.07
2.6
1.9
—
—
—
0
0
25
169
1.48
1.07
1.0
1.1
5.18
4.96
mg/g
0.14
25
161
36
262
1.38
1.05
2.8
2.7
—
—
—
0
0
5
22
2.27
1.03
1.2
1.3
—
—
—
0
0
5
22
2.27
1.03
1.0
1.0
—
—
—
0
0
449
4137
1.09
1.03
4.0
4.0
0.71
0.91
%
0.51
117
1116
16
252
0.63
1.03
1.1
1.1
—
—
—
0
0
118
999
1.18
1.03
1.2
1.1
122.00
119.05
%
0.55
109
917
20
130
1.54
1.02
1.0
1.0
—
—
—
0
0
9
47
1.92
1.02
1.3
1.1
—
11.54
—
0
15
68
545
1.25
1.01
2.9
2.5
1.24
1.34
e9/l
0.51
62
473
371
3391
1.10
1.01
1.4
1.4
—
—
—
0
0
458
4952
0.92
1.00
3.4
3.4
—
—
—
0
0
53
413
1.29
0.99
2.9
2.6
578.11
514.74
e6/l
0.50
47
336
80
656
1.22
0.98
1.3
1.4
—
—
—
0
0
50
388
1.29
0.97
1.6
1.3
—
—
—
0
0
301
2730
1.11
0.97
2.3
2.4
66.35
67.32
g/l
1.31
272
2515
266
2397
1.11
0.97
2.0
2.0
4.87
5.30
ug/l
0.25
235
2094
78
640
1.22
0.96
1.6
1.4
393.26
614.01
pmol/l
0.70
69
572
102
1206
0.84
0.95
6.2
5.1
1.13
1.22
mmol/l
0.77
90
1054
90
750
1.20
0.95
1.2
1.2
0.48
2.08
nmol/l
0.54
90
728
0
32
0.00
0.95
0.0
7.5
—
—
—
0
0
587
5492
1.08
0.94
3.7
3.6
32.17
32.86
%
0.88
441
4069
19
125
1.52
0.93
1.8
1.6
—
—
—
0
0
45
347
1.30
0.93
1.4
1.5
8437.50
58220.08
e6/l
1.15
32
240
134
1159
1.16
0.92
2.6
2.1
9.57
10.18
g/l
0.93
123
1060
768
8118
0.94
0.92
1.3
1.3
—
—
—
0
0
74
609
1.22
0.90
1.1
1.2
33.61
35.42
mg/l
0.19
64
510
135
1172
1.16
0.89
1.1
1.1
6.74
11.36
au/ml
—
10
80
62
501
1.24
0.89
1.0
1.0
—
—
—
0
0
5
101
0.49
0.89
1.0
1.1
—
—
—
0
0
19
127
1.50
0.88
1.2
1.2
—
—
—
0
0
83
693
1.20
0.87
2.1
1.6
85.04
51.37
mu/l
0.57
76
633
412
3817
1.08
0.87
3.9
3.8
0.69
0.71
%
0.02
106
988
21
144
1.46
0.87
1.3
2.2
—
—
—
0
0
21
144
1.46
0.87
1.9
2.0
2.60
101.16
ug/min
—
5
31
60
486
1.24
0.85
1.6
1.6
—
—
—
0
0
169
1497
1.13
0.85
1.4
1.3
472.55
462.57
mg/l
0.06
161
1435
26
356
0.73
0.85
1.5
1.5
—
—
—
0
0
144
1263
1.14
0.84
2.6
2.0
3.33
3.58
g/l
2.33
134
1172
646
6094
1.07
0.84
1.2
1.2
143.39
153.10
iu/ml
0.27
228
2493
214
1926
1.11
0.83
2.2
2.0
3.75
4.40
iu/l
0.70
91
794
52
416
1.25
0.83
1.5
1.6
5.92
6.00
mmol/l
0.07
40
330
144
1265
1.14
0.83
2.6
2.0
7.23
7.31
g/l
0.25
134
1172
46
363
1.27
0.82
1.4
1.6
1.19
1.26
promille
0.14
38
272
6
32
1.88
0.81
1.0
1.2
—
—
—
0
0
25
341
0.73
0.81
1.1
1.3
—
—
—
0
0
24
172
1.40
0.80
2.5
2.0
16.48
15.65
umol/l
0.18
24
172
70
581
1.21
0.80
2.3
2.7
1.45
1.44
%
0.00
64
528
32
419
0.76
0.79
1.2
1.3
1.66
1.62
g/l
0.46
32
419
0
24
0.00
0.79
0.0
1.0
—
0.06
—
0
12
161
1431
1.13
0.78
3.1
2.8
—
—
—
0
0
16
106
1.51
0.78
1.1
1.3
166.91
110.29
nmol/l
0.38
11
80
246
2240
1.10
0.78
2.4
2.3
—
—
—
0
0
58
474
1.23
0.78
1.0
1.1
5.08
8.81
iu/ml
1.27
19
129
69
825
0.83
0.77
4.2
2.7
—
—
—
0
0
0
27
0.00
0.77
0.0
1.0
—
0.21
—
0
19
946
9053
1.05
0.77
1.5
1.4
—
—
—
0
0
115
1001
1.15
0.77
2.0
2.0
5.35
5.43
mmol/24h
0.10
109
904
19
268
0.71
0.76
1.1
1.1
—
—
—
0
0
60
494
1.22
0.76
1.7
1.7
54.27
50.00
%
0.35
40
295
58
476
1.22
0.75
1.7
1.6
—
—
—
0
0
105
911
1.16
0.74
1.4
1.3
47.94
58.35
u/ml
—
8
66
49
602
0.81
0.73
2.1
2.5
7.07
7.20
mmol/l
0.14
49
587
23
167
1.38
0.73
3.5
2.9
31.38
27.60
umol/l
1.05
17
121
283
2605
1.09
0.73
2.6
2.5
68.50
72.36
e9/l
1.11
207
1901
83
708
1.17
0.73
3.3
3.7
—
—
—
0
0
189
1706
1.11
0.72
7.6
8.3
24.36
24.22
mmol/l
0.31
180
1669
105
914
1.15
0.71
1.0
1.1
—
—
—
0
0
149
1329
1.12
0.71
1.3
1.2
3.47
3.59
mmol/l
0.99
142
1252
75
880
0.85
0.70
3.8
3.7
—
—
—
0
0
43
532
0.81
0.70
1.1
1.2
0.38
1.51
u/ml
2.15
21
273
26
195
1.33
0.69
2.2
2.2
192.67
179.07
e6/l
0.09
15
107
144
1285
1.12
0.69
1.1
1.1
—
—
—
0
0
144
1285
1.12
0.69
1.1
1.1
—
—
—
0
0
12
77
1.56
0.68
1.1
1.0
—
—
—
0
0
47
383
1.23
0.67
2.6
3.1
—
—
—
0
0
80
686
1.17
0.67
1.5
1.6
—
—
—
0
0
340
3646
0.93
0.67
3.9
3.1
1.22
1.23
mmol/l
2.29
300
3188
17
119
1.43
0.66
1.3
1.2
—
—
—
0
0
91
790
1.15
0.66
1.3
1.3
—
—
—
0
0
13
86
1.51
0.66
1.1
1.1
—
—
—
0
0
102
894
1.14
0.65
1.0
1.1
—
—
—
0
0
446
4202
1.07
0.65
2.1
2.3
4.86
4.38
e9/l
0.29
388
3634
35
438
0.80
0.64
6.9
6.5
—
—
—
0
0
40
493
0.81
0.64
1.1
1.2
—
—
—
0
0
820
8546
0.95
0.63
2.0
2.0
—
—
—
0
0
17
121
1.41
0.62
1.3
2.2
—
—
—
0
0
69
590
1.17
0.62
1.0
1.1
199.49
209.54
mg/l
0.38
62
521
73
846
0.86
0.61
5.1
2.9
2.00
2.38
mmol/l
0.58
45
542
142
1278
1.11
0.61
3.2
2.8
24.80
24.79
mmol/l
0.03
134
1191
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
0.54
—
0
5
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
38
308
1.24
0.59
3.3
2.8
0.30
0.28
e9/l
0.05
38
302
95
837
1.14
0.58
1.8
2.1
—
—
—
0
0
8
54
1.48
0.57
2.3
2.0
0.75
0.85
u/field
—
8
54
55
647
0.85
0.56
2.1
2.4
1.34
1.40
mmol/l
0.20
55
630
103
1157
0.89
0.56
3.1
3.4
59.10
57.12
%
1.29
103
1157
66
764
0.86
0.56
8.0
6.5
105.63
105.46
mmol/l
0.13
60
685
114
1020
1.12
0.56
1.6
1.4
—
—
—
0
0
6
37
1.62
0.55
1.0
1.1
—
—
—
0
0
66
763
0.86
0.55
8.0
6.5
10.88
11.06
mmol/l
0.17
60
684
32
257
1.25
0.55
2.9
3.0
7.71
7.60
mg/l
0.03
24
194
34
276
1.23
0.53
1.2
1.3
151.88
139.72
mmol/24h
0.62
34
276
134
1214
1.11
0.53
1.2
1.1
—
—
—
0
0
154
1408
1.10
0.51
1.2
1.2
—
—
—
0
0
36
297
1.21
0.50
1.5
1.7
2.03
1.92
umol/l
0.47
31
276
238
2221
1.07
0.50
1.2
1.2
14.47
12.03
u/l
1.43
205
1841
35
422
0.83
0.49
8.2
4.2
5.80
7.39
mmol/l
2.73
26
351
26
207
1.26
0.49
1.3
1.9
—
—
—
0
0
18
136
1.32
0.49
1.1
1.1
—
—
—
0
0
119
1078
1.11
0.49
1.2
1.2
—
—
—
0
0
142
1298
1.10
0.49
5.3
4.2
—
—
—
0
0
30
244
1.23
0.48
1.1
1.1
—
—
—
0
0
221
2062
1.07
0.47
3.2
2.8
5.06
5.12
kpa
0.83
209
1978
19
146
1.30
0.47
2.0
1.7
7.17
8.35
ug/l
1.75
19
146
66
750
0.88
0.46
4.8
4.3
42.45
87.78
u/ml
0.80
15
262
23
182
1.26
0.46
1.7
2.3
166.61
161.63
nmol/l
0.09
23
158
48
412
1.17
0.45
1.3
1.4
12.51
9.86
umol/l
1.11
48
395
21
165
1.27
0.44
2.5
2.1
—
—
—
0
0
10
69
1.45
0.44
1.1
1.2
—
—
—
0
0
31
373
0.83
0.44
3.3
3.2
—
—
—
0
0
57
498
1.15
0.43
3.3
2.7
—
—
—
0
0
136
1251
1.09
0.43
1.5
1.3
—
—
—
0
0
55
480
1.15
0.42
1.1
1.2
52.04
55.69
nmol/l
0.34
55
475
336
3194
1.05
0.42
7.1
7.1
96.41
96.16
%
0.31
320
3072
0
15
0.00
0.41
0.0
2.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
2.0
—
—
—
0
0
0
15
0.00
0.41
0.0
2.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
69.00
—
0
11
104
948
1.10
0.40
1.8
1.7
7514.47
8382.44
e6/l
0.23
81
691
0
18
0.00
0.40
0.0
1.1
—
36.85
—
0
18
0
19
0.00
0.39
0.0
1.2
—
69.88
—
0
19
83
750
1.11
0.39
2.6
2.5
77.22
78.93
ug/min
0.02
50
467
16
124
1.29
0.38
2.4
1.6
—
—
—
0
0
9
67
1.34
0.38
1.4
1.9
1.23
0.99
mmol/l
—
9
62
56
495
1.13
0.38
1.2
1.2
—
—
—
0
0
50
568
0.88
0.37
1.0
1.0
0.21
1.68
u/ml
1.42
17
177
182
1940
0.94
0.37
1.6
1.5
0.34
0.49
nmol/l
3.26
149
1542
216
2037
1.06
0.37
3.1
2.8
7.41
7.41
ph
0.54
22
283
10
72
1.39
0.36
1.1
1.2
—
—
—
0
0
32
272
1.18
0.36
1.6
1.4
—
—
—
0
0
12
90
1.33
0.35
1.9
1.5
—
—
—
0
0
388
3724
1.04
0.35
6.6
6.6
1.10
0.92
mmol/l
0.44
301
2897
37
319
1.16
0.35
2.8
2.9
—
—
—
0
0
25
208
1.20
0.35
2.6
2.1
—
—
—
0
0
61
546
1.12
0.35
2.1
1.7
—
—
—
0
0
39
339
1.15
0.34
1.1
1.1
—
—
—
0
0
64
576
1.11
0.33
2.4
2.4
—
—
—
0
0
70
634
1.11
0.33
1.4
1.4
—
—
—
0
0
41
359
1.14
0.33
1.0
1.1
0.35
4.27
nmol/l
—
10
66
6
46
1.30
0.33
1.2
1.4
19.67
20.76
%
—
6
37
24
201
1.19
0.32
1.2
1.2
—
—
—
0
0
5003
49778
1.02
0.31
15.4
13.4
331.92
331.64
g/l
1.60
4973
49448
119
1110
1.07
0.30
1.1
1.1
—
—
—
0
0
385
3712
1.04
0.30
6.7
6.6
5.08
5.05
kpa
0.37
367
3559
385
3712
1.04
0.30
6.7
6.5
13.64
13.47
kpa
0.22
365
3553
22
184
1.20
0.30
1.0
1.0
264.57
337.92
ng/l
1.17
14
138
10
75
1.33
0.30
1.1
1.1
—
—
—
0
0
7
55
1.27
0.30
1.6
1.7
—
—
—
0
0
67
734
0.91
0.29
1.1
1.1
—
—
—
0
0
10
130
0.77
0.29
1.0
1.1
—
—
—
0
0
10
130
0.77
0.29
1.0
1.1
—
—
—
0
0
10
130
0.77
0.29
1.0
1.1
—
—
—
0
0
58
526
1.10
0.28
1.1
1.1
—
—
—
0
0
29
251
1.16
0.28
1.0
1.1
—
—
—
0
0
49
441
1.11
0.27
1.2
1.2
—
—
—
0
0
20
168
1.19
0.27
1.1
1.2
5.60
5.46
nmol/l
0.06
20
156
254
2437
1.04
0.26
2.2
2.5
173.00
121.10
ng/l
0.89
223
2180
107
1142
0.94
0.26
1.4
1.5
7.03
6.76
mmol/l
0.50
100
1035
315
3038
1.04
0.26
7.6
7.3
117.49
120.86
g/l
2.78
307
2951
11
138
0.80
0.25
1.0
1.1
0.10
0.07
u/ml
0.14
11
138
116
1091
1.06
0.25
1.2
1.2
—
—
—
0
0
9
73
1.23
0.25
2.0
1.7
2.65
3.09
mmol/l
—
9
67
22
188
1.17
0.25
1.0
1.0
579.79
776.02
ng/l
1.66
14
139
18
213
0.84
0.25
1.7
1.5
—
—
—
0
0
31
273
1.14
0.25
1.0
1.1
—
—
—
0
0
44
487
0.90
0.25
1.5
1.6
90.57
90.62
%
0.03
44
481
42
378
1.11
0.24
1.5
1.6
31.24
39.65
%
0.80
29
209
6
82
0.73
0.24
1.3
1.1
—
—
—
0
0
157
1494
1.05
0.24
3.2
2.8
25.66
25.39
mmol/l
0.52
151
1435
42
379
1.11
0.23
2.2
2.6
2.19
1.24
g/24h
1.00
16
194
5
40
1.25
0.22
5.6
1.4
—
—
—
0
0
7
95
0.74
0.22
3.3
1.9
—
—
—
0
0
21
242
0.87
0.22
1.2
1.0
0.22
2.99
u/ml
1.87
14
128
45
493
0.91
0.22
1.3
1.2
44.84
19.20
u/l
0.41
36
430
482
4939
0.97
0.21
1.4
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
6.1
—
349.91
—
0
11
0
10
0.00
0.21
0.0
1.1
—
127.20
—
0
5
13
156
0.83
0.21
4.7
2.8
198.08
94.65
ng/l
—
5
70
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
96
905
1.06
0.21
1.3
1.3
1.13
1.30
nmol/l
1.25
90
774
79
843
0.94
0.21
1.1
1.1
106.21
12154.09
iu/ml
0.63
21
221
32
356
0.90
0.21
1.3
1.4
67.88
68.17
umol/l
0.04
32
356
22
251
0.88
0.20
1.1
1.1
—
—
—
0
0
165
1721
0.96
0.20
1.2
1.1
2.28
2.06
u/ml
0.12
71
810
122
1282
0.95
0.20
1.0
1.1
1.15
4.18
u/ml
3.95
45
574
78
831
0.94
0.20
3.4
2.4
0.79
0.83
nmol/l
0.25
64
703
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
5.95
—
0
5
0
14
0.00
0.20
0.0
1.1
—
15.32
—
0
8
13
108
1.20
0.20
1.5
1.6
—
—
—
0
0
9
115
0.78
0.20
1.0
1.0
—
—
—
0
0
15
127
1.18
0.19
1.0
1.0
—
—
—
0
0
37
406
0.91
0.19
2.8
2.5
—
—
—
0
0
6
52
1.15
0.19
1.0
1.1
—
3.50
—
0
5
124
1299
0.95
0.19
5.5
4.8
0.84
0.93
%
2.21
118
1213
71
756
0.94
0.18
2.1
2.1
16.65
16.70
%
0.04
34
365
277
2690
1.03
0.18
1.1
1.1
—
—
—
0
0
477
4870
0.98
0.17
1.2
1.3
—
—
—
0
0
36
393
0.92
0.17
1.7
2.1
—
—
—
0
0
1198
11838
1.01
0.17
3.0
2.9
—
—
—
0
0
29
262
1.11
0.17
1.3
1.5
127.34
129.18
nmol/l
0.10
29
262
11
131
0.84
0.17
1.2
1.0
—
—
—
0
0
11
131
0.84
0.17
1.2
1.0
—
—
—
0
0
11
131
0.84
0.17
1.2
1.0
—
—
—
0
0
392
4009
0.98
0.17
1.4
1.4
—
—
—
0
0
5
69
0.72
0.16
1.0
1.0
—
—
—
0
0
8
68
1.18
0.16
2.5
2.2
—
—
—
0
0
8
72
1.11
0.16
1.0
1.3
—
263.13
—
0
7
126
1310
0.96
0.15
5.2
4.7
1.75
1.71
%
0.13
117
1223
27
245
1.10
0.15
1.7
1.7
—
—
—
0
0
12
102
1.18
0.15
2.7
1.9
954.14
26870.79
e6/l
—
7
52
16
140
1.14
0.15
1.4
1.5
—
—
—
0
0
53
564
0.94
0.15
1.0
1.0
0.41
0.77
u/ml
0.87
15
126
19
213
0.89
0.15
1.6
1.5
3.88
4.80
%
—
8
41
13
112
1.16
0.14
1.2
1.2
—
—
—
0
0
35
378
0.93
0.14
1.1
1.1
1403.29
1522.84
miu/ml
0.29
35
378
115
1195
0.96
0.14
1.0
1.1
1.24
3.75
u/ml
4.96
39
469
14
122
1.15
0.13
1.0
1.1
—
213.33
—
0
9
158
1531
1.03
0.13
1.3
1.3
189.17
142.01
titre
0.18
12
144
8
100
0.80
0.13
1.5
2.0
—
—
—
0
0
50
471
1.06
0.13
1.1
1.1
1.06
1.05
ratio
0.36
20
176
197
2023
0.97
0.13
5.6
4.6
—
—
—
0
0
30
324
0.93
0.12
1.5
1.2
42.14
70.71
%
—
7
34
10
85
1.18
0.12
1.3
1.3
—
—
—
0
0
39
365
1.07
0.12
1.3
1.3
—
—
—
0
0
29
268
1.08
0.12
1.0
1.1
10.32
10.97
u/ml
—
10
175
23
210
1.10
0.12
1.5
1.4
—
—
—
0
0
33
307
1.08
0.12
1.5
1.7
1.75
3.22
nmol/l
0.96
25
249
16
143
1.12
0.11
3.2
1.6
—
—
—
0
0
193
1885
1.02
0.11
1.3
1.3
—
—
—
0
0
541
5479
0.99
0.10
1.7
1.7
—
—
—
0
0
109
1123
0.97
0.10
2.0
1.9
1.05
1.88
ug/l
0.98
96
988
5
45
1.11
0.09
3.4
2.8
—
—
—
0
0
5
45
1.11
0.09
1.2
1.1
6.32
13.13
pmol/l
—
5
45
12
106
1.13
0.09
1.0
1.1
—
—
—
0
0
10
114
0.88
0.09
1.0
7.3
—
—
—
0
0
322
3270
0.98
0.09
1.4
1.4
—
—
—
0
0
98
1010
0.97
0.09
3.3
3.4
15.71
22.80
mg/l
2.26
48
612
28
262
1.07
0.09
1.2
1.4
71.29
141.57
nmol/24h
0.63
28
262
469
4634
1.01
0.09
1.3
1.3
131.59
178.93
u/ml
0.95
431
4289
25
268
0.93
0.09
1.6
1.5
1.89
2.76
u/field
0.24
18
190
21
227
0.92
0.09
1.5
1.5
—
—
—
0
0
26
243
1.07
0.08
1.3
1.2
—
—
—
0
0
5
61
0.82
0.08
1.8
7.5
—
—
—
0
0
17
185
0.92
0.08
1.0
1.1
—
—
—
0
0
982
9886
0.99
0.07
1.6
1.6
60648592.12
31167140.05
pmol/l
0.65
864
8554
11
98
1.12
0.07
1.0
1.1
—
—
—
0
0
23
215
1.07
0.07
1.1
1.1
—
—
—
0
0
60
580
1.03
0.07
1.6
1.4
55.76
65.49
mmol/l
1.44
55
452
322
3259
0.99
0.07
1.4
1.4
—
—
—
0
0
9
85
1.06
0.07
1.1
1.3
—
99.48
—
0
5
212
2088
1.02
0.07
1.1
1.1
7.92
5.19
u/ml
0.20
39
333
49
472
1.04
0.06
1.3
1.5
5.31
5.23
mmol/l
0.26
44
451
196
1990
0.98
0.06
7.6
6.4
24.65
24.43
mmol/l
0.43
185
1885
9
102
0.88
0.06
2.3
2.9
—
—
—
0
0
174
1768
0.98
0.06
1.2
1.2
—
—
—
0
0
155
1524
1.02
0.06
1.3
1.3
773.75
1003.47
titre
—
8
75
20
213
0.94
0.06
2.5
2.1
1.73
1.16
ug/l
0.44
20
201
49
474
1.03
0.05
1.2
1.3
—
—
—
0
0
142
1443
0.98
0.05
1.1
1.1
0.64
1.47
u/ml
2.26
56
676
88
861
1.02
0.05
1.7
2.0
127.90
130.49
g/l
0.57
59
632
16
149
1.07
0.05
2.8
2.0
2.99
2.96
ug/l
0.02
16
136
21
222
0.95
0.05
1.4
1.4
13718.00
79994.38
e6/l
1.05
12
119
44
427
1.03
0.04
1.3
1.5
278.86
279.61
mosm/kgh2o
0.07
35
338
173
1749
0.99
0.04
9.9
8.5
—
—
—
0
0
19
200
0.95
0.03
1.2
1.2
—
0.31
g/l
—
0
10
21
200
1.05
0.03
1.2
1.2
16.83
9.85
%
—
6
26
146
1443
1.01
0.03
1.1
1.1
0.43
1.00
u/ml
1.46
51
569
1815
18189
1.00
0.03
1.6
1.7
—
—
—
0
0
61
598
1.02
0.03
1.0
1.1
—
—
—
0
0
44
429
1.03
0.03
1.3
1.2
—
—
—
0
0
119
1176
1.01
0.03
1.1
1.1
2.60
3.06
u/ml
0.23
67
659
71
698
1.02
0.03
1.2
1.5
—
—
—
0
0
333
3349
0.99
0.03
1.5
1.5
—
—
—
0
0
200
1984
1.01
0.03
1.3
1.3
2.84
3.48
ug/l
1.39
181
1806
47
460
1.02
0.02
1.1
1.1
—
—
—
0
0
34
331
1.03
0.02
1.1
1.1
—
—
—
0
0
42
429
0.98
0.02
1.2
1.3
—
—
—
0
0
152
1530
0.99
0.01
1.1
1.1
4.94
4.95
u/ml
0.01
67
772
102
1027
0.99
0.00
1.0
1.1
0.02
0.27
u/ml
1.14
24
247
102
1027
0.99
0.00
3.2
2.2
—
—
—
0
0
166
1666
1.00
0.00
2.1
2.1
4.67
5.07
umol/l
0.29
124
1217
10
98
1.02
0.00
5.6
2.0
—
—
—
0
0
20
198
1.01
0.00
1.6
1.6
13.05
11.43
u/l
0.34
20
191
20
202
0.99
0.00
1.1
1.0
—
—
—
0
0
23
228
1.01
0.00
1.1
1.0
—
—
—
0
0
10
105
0.95
0.00
1.1
1.1
—
—
—
0
0
25
252
0.99
0.00
1.3
1.4
17562.72
2742.41
e6/l
0.46
18
180
35
352
0.99
0.00
1.8
1.4
5.35
5.08
u/l
0.19
25
308
52
525
0.99
0.00
1.0
1.0
0.17
0.30
u/ml
0.59
13
114
83
825
1.01
0.00
1.2
1.4
28.06
31.59
nmol/l
0.70
77
754
11
107
1.03
0.00
1.0
1.2
—
—
—
0
0
34
343
0.99
0.00
1.8
1.9
2.72
2.01
u/field
0.31
18
167
17
171
0.99
0.00
2.1
1.4
—
—
—
0
0
7
70
1.00
0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
6.08
—
0
7
0
8
0.00
0.00
0.0
1.5
—
1433.49
—
0
8
6
59
1.02
-0.00
1.2
1.2
—
2.16
—
0
9
0
9
0.00
-0.00
0.0
5.2
—
1.14
—
0
9
7
79
0.89
-0.00
1.7
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
20
200
1.00
-0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
308.80
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
82
0.98
-0.00
1.7
1.9
—
—
—
0
0
10
100
1.00
-0.00
2.5
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
-0.00
4.1
2.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_FEMALE_GENITAL_LSIL and mortality.

Females

Parameter HR [95% CI] p-value
N14_FEMALE_GENITAL_LSIL 1.019 [0.91, 1.15] 0.75
Birth year 0.991 [0.98, 1.0] 0.052

During the follow-up period (1.1.1998 — 31.12.2019), 1028 out of 27266 females with N14_FEMALE_GENITAL_LSIL died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_FEMALE_GENITAL_LSIL.

N-year risk Females Males
1 0.107% No data
5 0.611% No data
10 1.459% No data
15 2.814% No data
20 4.773% No data

Relationships between endpoints

Index endpoint: N14_FEMALE_GENITAL_LSIL – LSIL lesion of the cervix uteri, vagina or vulva

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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