No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
517 |
4. Check minimum number of eventsNone |
517 |
5. Include endpointsNone |
517 |
6. Filter based on genotype QC (FinnGen only) |
517 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Similar endpoints
↥List of similar endpoints to
LSIL lesion of the vagina
based on the number of shared cases.
Similar with more cases:
- All dysplastic lesions of the vagina
- Other noninflammatory disorders of vagina
- LSIL lesion of the cervix uteri, vagina or vulva
- All dysplastic lesions of the cervix uteri, vagina or vulva
- Noninflammatory disorders of female genital tract
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2429 | 2429 | - |
| Only index persons | 2363 | 2363 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.07 | - |
| Only index persons | 0.09 | 0.09 | - |
| Median age at first event (years) | |||
| Whole population | - | 50.78 | - |
| Only index persons | - | 50.56 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 517 | 517 | - |
| Unadjusted period prevalence (%) | 0.18 | 0.18 | - |
| Median age at first event (years) | 51.57 | 51.57 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 449
- Matched controls
- 4491
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N89.0
ICD-10 Finland
Mild vaginal dysplasia
+∞
323.0
449
*
ULA02
NOMESCO Finland
Kolposcopy
74.3
290.3
394
394
LEB00
NOMESCO Finland
Biopsy of vagina
118.6
246.3
255
49
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
37.2
229.0
351
394
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
16.0
143.7
289
455
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
246.4
126.9
125
7
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
17.0
126.1
225
250
N87.0
ICD-10 Finland
Mild cervical dysplasia
25.4
99.0
143
81
A63.0
ICD-10 Finland
Anogenital (venereal) warts
21.1
83.6
128
83
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
24.9
77.9
112
59
LDA10
NOMESCO Finland
Curettage of cervix uteri
12.2
67.1
131
147
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
12.4
65.4
126
137
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
162.7
55.3
57
*
N90.0
ICD-10 Finland
Mild vulvar dysplasia
143.4
48.9
51
*
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
+∞
31.6
30
*
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
27.3
29.3
40
16
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
71.0
29.3
33
5
N87.1
ICD-10 Finland
Moderate cervical dysplasia
10.0
26.9
55
62
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
14.3
25.3
43
33
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
15.7
23.9
39
27
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
8.2
19.9
45
60
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.5
19.0
233
1356
G01AA10
ATC
clindamycin; vaginal
2.7
17.7
150
703
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
165.5
15.6
16
*
D06BB10
ATC
imiquimod; topical
4.9
13.7
45
99
ZXC10
NOMESCO Finland
Use of laser
9.3
13.7
28
32
X86
ICPC
Abnormal cervix smear
19.0
13.5
20
11
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
23.4
13.0
18
8
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
123.0
11.5
12
*
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.9
10.3
282
2089
L04AX01
ATC
azathioprine; systemic
4.1
10.0
38
98
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
26.7
9.9
13
5
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.6
9.4
74
321
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
51.0
8.7
10
*
ZXC00
NOMESCO Finland
Use of diathermy
9.1
7.6
15
17
D06BB04
ATC
podophyllotoxin; topical
3.1
7.3
39
134
P01BA02
ATC
hydroxychloroquine; oral
2.4
6.9
57
255
LEB10
NOMESCO Finland
Excision of lesion of vagina
8.5
6.9
14
17
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.7
6.8
44
171
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
3.6
6.8
29
85
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
5.7
6.0
16
29
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
70
31
25.96
97.78
3.8
1.5
—
—
—
0
0
329
1275
5.35
77.51
2.9
1.4
—
—
—
0
0
127
283
5.62
56.29
2.8
1.4
—
—
—
0
0
114
623
2.06
9.77
2.0
1.8
—
—
—
0
0
85
425
2.20
9.13
1.8
1.7
—
—
—
0
0
99
532
2.06
8.82
3.8
3.9
32.3
33.1
%
0.29
59
354
69
327
2.28
8.41
1.6
1.6
—
—
—
0
0
117
679
1.93
8.35
2.2
2.0
—
—
—
0
0
401
3371
1.84
7.72
5.7
4.0
11.7
11.2
mm/h
0.46
373
3126
24
70
3.55
7.20
2.2
1.7
—
—
—
0
0
15
32
4.80
6.73
1.3
1.2
—
—
—
0
0
39
167
2.44
5.98
3.6
1.9
—
—
—
0
0
12
24
5.10
5.77
1.8
1.7
824.3
501.1
e6/l
1.09
12
19
12
24
5.10
5.77
1.8
1.4
876.8
840.4
e6/l
—
5
8
150
1032
1.64
5.76
2.5
1.9
—
—
—
0
0
235
1800
1.56
5.72
6.7
4.9
1.2
1.2
mmol/l
0.32
202
1632
35
150
2.43
5.37
4.1
1.5
0.2
0.2
g/l
4.06
35
141
36
157
2.39
5.32
4.1
1.5
1.0
1.2
g/l
4.50
36
147
50
251
2.10
5.29
11.0
7.0
7.5
7.9
mmol/l
0.21
45
238
385
3335
1.60
5.15
10.7
6.8
75.8
75.7
u/l
0.02
362
3118
254
2014
1.51
5.08
7.6
5.6
1.2
1.2
mmol/l
0.04
212
1694
218
1674
1.52
5.07
5.6
4.0
36.8
36.2
g/l
0.99
201
1569
80
483
1.78
4.91
6.9
5.1
—
—
—
0
0
23
84
2.82
4.84
2.9
4.0
33.4
38.8
mg/l
0.25
23
68
23
84
2.82
4.84
2.9
4.0
41.2
23.8
mg/l
0.72
23
66
13
33
4.02
4.74
1.4
1.4
—
—
—
0
0
32
143
2.32
4.51
1.6
1.2
15.9
2.2
u/ml
—
7
17
305
2555
1.47
4.39
13.0
8.6
3.7
3.9
e9/l
1.48
278
2247
20
72
2.85
4.33
13.8
5.7
593.0
164.8
iu/ml
—
7
9
32
146
2.27
4.31
1.6
1.2
17.3
11.6
u/ml
—
8
30
37
181
2.12
4.21
1.4
1.7
—
—
—
0
0
170
1285
1.48
4.08
3.0
2.3
56.4
55.7
u/l
0.11
160
1184
92
608
1.62
4.04
3.2
2.4
1.0
1.2
e6/l
0.28
55
325
70
436
1.70
3.85
8.0
4.2
1.0
1.0
mmol/l
0.09
63
398
11
29
3.85
3.82
2.5
1.6
1.0
1.0
g/l
0.33
11
29
33
163
2.09
3.69
2.2
1.8
—
—
—
0
0
21
87
2.47
3.51
1.5
1.2
—
—
—
0
0
69
442
1.65
3.42
4.8
2.3
5.4
6.0
umol/l
0.26
61
379
16
59
2.77
3.35
1.3
1.3
—
—
—
0
0
241
1998
1.39
3.31
2.7
2.3
78.4
77.3
nmol/l
0.24
210
1819
16
60
2.72
3.25
1.3
1.3
—
—
—
0
0
16
60
2.72
3.25
1.3
1.3
—
—
—
0
0
18
72
2.55
3.24
1.7
1.3
126.6
121.3
u/ml
—
5
17
30
151
2.05
3.22
2.0
1.7
—
—
—
0
0
8
15
5.40
3.20
1.4
1.1
—
—
—
0
0
8
15
5.40
3.20
1.4
1.1
—
—
—
0
0
83
566
1.56
3.19
3.4
2.5
4.2
4.8
e6/l
0.20
45
285
454
4224
1.61
3.18
11.8
10.3
84.9
85.5
ml/min/173m2
0.24
375
3407
332
2919
1.38
3.09
5.7
4.2
—
1309.1
—
0
42
16
62
2.63
3.07
1.3
1.3
—
—
—
0
0
16
62
2.63
3.07
1.3
1.3
—
—
—
0
0
16
62
2.63
3.07
1.3
1.3
—
—
—
0
0
8
16
5.06
3.06
1.4
1.1
—
—
—
0
0
8
16
5.06
3.06
1.0
1.9
—
—
—
0
0
8
16
5.06
3.06
1.4
1.1
—
—
—
0
0
8
16
5.06
3.06
1.0
1.9
—
—
—
0
0
7
12
5.90
3.03
3.1
2.4
43.3
56.3
ug/l
—
7
12
17
69
2.51
2.99
1.3
1.3
—
—
—
0
0
256
2169
1.36
2.97
8.8
5.5
9.4
9.5
umol/l
0.17
247
2051
22
102
2.21
2.91
1.3
1.3
—
—
—
0
0
270
2316
1.35
2.84
4.8
3.9
6.4
6.4
mmol/l
0.01
245
2127
133
1024
1.40
2.76
2.5
2.1
2.7
2.9
mg/l
0.43
106
878
200
1647
1.35
2.73
1.9
1.9
100.3
98.7
pmol/l
0.18
94
814
248
2111
1.34
2.70
4.0
3.7
—
—
—
0
0
459
4315
1.57
2.68
4.5
4.1
5.7
5.7
mmol/l
0.90
406
3986
24
120
2.05
2.65
1.5
1.2
44.3
27.5
u/ml
—
7
11
134
1042
1.39
2.61
4.0
2.7
0.3
0.4
e6/l
0.66
102
768
5
8
6.30
2.37
2.0
1.6
—
—
—
0
0
44
278
1.64
2.35
1.8
1.5
—
—
—
0
0
11
41
2.72
2.29
1.8
1.7
24.4
16.8
mg/l
—
5
10
82
602
1.43
2.21
4.6
2.8
0.8
0.8
mmol/l
0.08
73
564
143
1152
1.33
2.19
1.3
1.2
0.6
2.0
u/ml
1.91
32
310
8
25
3.23
2.10
1.5
2.1
—
—
—
0
0
75
547
1.43
2.10
2.8
2.1
2.4
2.4
g/l
0.33
68
507
510
4994
2.57
2.07
23.6
17.4
132.1
132.9
g/l
0.88
503
4929
7
20
3.53
2.06
1.4
1.1
—
—
—
0
0
176
1471
1.30
2.06
5.4
2.9
29.5
28.1
u/l
0.42
170
1407
17
83
2.08
2.03
1.6
1.2
—
—
—
0
0
170
1417
1.30
2.02
3.1
3.0
19.2
26.0
ng/l
0.38
98
826
492
4749
1.74
2.01
14.1
9.4
24.2
23.7
u/l
0.26
475
4595
69
500
1.44
2.00
3.0
2.2
22.8
23.1
%
0.07
61
424
54
373
1.50
1.99
5.5
6.0
104.1
104.3
mmol/l
0.06
54
362
77
570
1.41
1.99
1.9
1.8
—
—
—
0
0
336
3055
1.29
1.98
3.9
2.8
38.4
39.8
u/l
0.16
317
2890
21
113
1.89
1.94
1.1
1.4
26.2
25.6
u/l
0.02
14
94
9
34
2.68
1.87
1.0
1.1
312.7
291.7
mg/l
—
9
29
470
4499
1.49
1.87
14.8
12.1
139.6
139.7
mmol/l
0.37
449
4363
471
4511
1.50
1.86
15.1
12.2
3.9
3.9
mmol/l
0.08
449
4365
49
338
1.50
1.83
4.4
3.5
4.4
4.6
pmol/l
0.85
44
300
9
35
2.60
1.81
1.6
1.7
—
—
—
0
0
12
54
2.25
1.75
1.2
1.1
—
—
—
0
0
6
18
3.36
1.75
1.3
1.1
—
—
—
0
0
37
244
1.56
1.70
1.7
1.6
—
—
—
0
0
113
911
1.31
1.70
1.6
1.5
22.8
22.3
nmol/l
0.12
95
779
77
593
1.35
1.59
3.0
2.1
13.0
13.8
umol/l
0.51
70
549
7
27
2.61
1.52
1.1
1.1
—
—
—
0
0
145
1224
1.26
1.51
2.7
2.0
93.8
192.9
u/l
1.20
138
1159
21
125
1.71
1.46
1.3
1.2
—
—
—
0
0
466
4486
1.39
1.45
15.8
11.5
19.5
19.6
mg/l
0.02
375
3432
9
39
2.33
1.43
1.0
1.0
—
—
—
0
0
361
3833
0.81
1.42
18.2
14.0
13.6
13.6
%
0.26
352
3758
11
53
2.10
1.39
1.2
1.0
—
—
—
0
0
462
4448
1.36
1.38
4.4
4.1
4.9
4.9
mmol/l
0.72
423
4166
107
883
1.27
1.35
2.7
2.9
518.2
918.1
ng/l
1.90
91
743
39
277
1.44
1.31
1.0
1.1
—
—
—
0
0
27
178
1.55
1.29
1.6
1.7
—
—
—
0
0
28
405
0.67
1.23
2.9
3.0
—
—
—
0
0
30
205
1.49
1.23
1.5
1.3
127.0
238.2
miu/ml
1.01
14
105
83
672
1.28
1.23
1.6
1.7
1027.7
1205.1
nmol/l
1.15
61
499
5
19
2.65
1.22
2.2
3.2
—
—
—
0
0
38
274
1.42
1.19
1.7
2.7
66.4
67.5
g/l
0.37
33
249
6
26
2.32
1.19
4.3
1.9
94.5
104.3
%
—
6
26
8
39
2.07
1.15
5.8
2.5
5.9
2.7
nmol/l
—
8
39
167
1469
1.20
1.15
2.7
3.3
2.4
2.4
mmol/l
0.27
139
1305
5
113
0.44
1.14
1.4
1.5
—
—
—
0
0
7
31
2.27
1.10
2.1
1.5
—
—
—
0
0
5
21
2.39
1.09
2.8
4.2
5329.0
685.8
u/ml
—
5
21
5
21
2.39
1.09
1.8
1.4
7.9
8.4
ug/l
—
5
21
8
41
1.97
1.09
1.5
1.0
—
—
—
0
0
7
32
2.20
1.08
2.3
1.3
—
—
—
0
0
7
32
2.20
1.08
2.3
1.3
—
—
—
0
0
7
32
2.20
1.08
2.3
1.3
—
—
—
0
0
21
137
1.56
1.07
6.0
3.0
23.5
24.4
mmol/l
0.64
21
126
9
46
1.97
1.04
1.3
1.2
—
—
—
0
0
9
46
1.97
1.04
1.3
1.2
—
—
—
0
0
238
2178
1.17
1.02
4.3
3.4
0.0
0.0
estimate
0.00
30
416
19
123
1.57
1.01
3.6
2.1
196.0
168.5
%
0.86
19
118
43
328
1.34
0.99
4.9
3.0
97.9
72.3
ng/l
0.68
38
295
457
4429
1.27
0.99
4.4
4.0
1.6
1.6
mmol/l
0.43
411
4132
7
36
1.96
0.97
2.1
1.5
—
—
—
0
0
7
36
1.96
0.97
2.6
1.9
—
—
—
0
0
0
31
0.00
0.96
0.0
1.5
—
—
—
0
0
54
428
1.29
0.96
2.4
2.1
396.3
370.0
nmol/l
0.50
47
399
97
825
1.22
0.95
1.5
1.6
460.7
30186424.3
pmol/l
1.05
84
699
86
724
1.23
0.93
2.5
2.6
2.4
2.4
mmol/l
0.81
75
642
12
70
1.73
0.93
1.2
1.2
—
—
—
0
0
238
2191
1.16
0.92
5.9
4.7
0.0
0.0
estimate
0.50
35
421
6
30
2.01
0.87
1.3
1.1
—
—
—
0
0
110
957
1.19
0.85
1.3
1.3
12.4
12.2
u/ml
0.01
43
383
14
88
1.61
0.85
2.7
2.2
—
—
—
0
0
8
138
0.57
0.84
1.6
1.7
—
—
—
0
0
6
113
0.53
0.84
2.5
1.6
—
—
—
0
0
11
65
1.71
0.83
1.2
1.3
—
—
—
0
0
24
326
0.72
0.80
4.2
3.5
1.2
1.2
mmol/l
0.20
24
281
0
24
0.00
0.79
0.0
1.4
—
—
—
0
0
30
393
0.75
0.79
1.4
1.3
40.0
28.7
iu/l
0.73
22
337
6
33
1.83
0.79
1.2
1.0
—
—
—
0
0
238
2210
1.14
0.79
4.4
3.4
0.0
0.0
estimate
0.80
35
412
463
4515
1.24
0.78
4.7
4.5
2.9
2.9
mmol/l
0.43
415
4199
0
26
0.00
0.78
0.0
1.1
—
—
—
0
0
0
28
0.00
0.76
0.0
1.3
—
—
—
0
0
119
1054
1.17
0.75
1.8
1.7
1.0
0.9
mg/l
0.16
80
804
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
58
692
0.82
0.73
2.6
3.3
95.1
293.6
ng/l
0.99
37
442
6
109
0.55
0.73
1.2
1.6
—
—
—
0
0
9
57
1.59
0.71
1.9
1.3
—
—
—
0
0
5
26
1.93
0.71
3.2
1.5
30.0
27.0
ug/l
—
5
26
116
1033
1.16
0.69
4.1
2.3
309.6
5167.0
umol/l
3.88
102
906
438
4262
1.18
0.67
4.0
3.6
1.2
1.2
mmol/l
0.03
387
3958
28
216
1.31
0.65
1.5
1.4
—
—
—
0
0
395
3821
1.14
0.63
4.7
4.4
14.6
14.5
pmol/l
0.55
364
3542
0
21
0.00
0.60
0.0
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
0.3
—
0
15
415
4032
1.15
0.60
5.1
4.9
37.8
38.5
mmol/mol
1.39
374
3764
19
140
1.37
0.59
1.5
1.4
343.2
315.6
ug/g
0.22
13
80
0
23
0.00
0.58
0.0
1.1
—
121.4
—
0
16
108
971
1.14
0.57
1.5
1.3
19.6
28.8
iu/ml
1.03
30
315
45
377
1.21
0.55
1.8
1.8
—
—
—
0
0
25
195
1.30
0.55
4.7
2.9
1.5
1.9
mmol/l
0.24
20
147
6
38
1.59
0.54
1.5
1.3
—
—
—
0
0
34
278
1.24
0.53
5.5
3.0
5.7
5.9
kpa
0.62
34
273
61
529
1.17
0.52
2.1
1.5
1.2
1.3
%
1.38
52
472
42
353
1.21
0.51
2.6
2.1
71.0
74.5
ml/min/173m2
0.20
14
136
10
67
1.50
0.50
2.0
1.5
—
—
—
0
0
7
46
1.53
0.48
1.0
1.1
—
—
—
0
0
19
146
1.31
0.47
1.2
1.2
—
—
—
0
0
27
331
0.81
0.47
1.2
1.5
—
—
—
0
0
44
375
1.19
0.47
1.7
1.7
—
—
—
0
0
18
232
0.77
0.47
1.3
1.5
—
—
—
0
0
19
147
1.30
0.46
1.2
1.2
—
—
—
0
0
232
2207
1.09
0.44
3.4
2.8
89.1
75.8
ug/l
0.77
213
2067
15
196
0.76
0.43
1.3
1.4
—
—
—
0
0
15
196
0.76
0.43
1.3
1.4
—
—
—
0
0
15
196
0.76
0.43
1.3
1.4
—
—
—
0
0
15
196
0.76
0.43
1.3
1.4
—
—
—
0
0
35
295
1.20
0.43
1.9
1.4
—
—
—
0
0
16
206
0.77
0.42
1.3
1.5
—
—
—
0
0
8
58
1.39
0.41
1.0
1.1
—
—
—
0
0
115
1061
1.11
0.41
1.6
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
6.5
—
—
—
0
0
8
59
1.36
0.41
1.3
1.5
—
—
—
0
0
17
132
1.30
0.41
1.2
1.8
—
—
—
0
0
32
269
1.20
0.40
6.7
5.9
1.3
1.2
mmol/l
0.14
32
258
5
35
1.43
0.39
1.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.5
—
—
—
0
0
119
1106
1.10
0.37
4.0
3.8
12.6
8.2
mg/mmol
0.38
63
643
9
69
1.31
0.37
1.2
1.2
—
—
—
0
0
338
3284
1.08
0.37
3.3
3.4
—
—
—
0
0
9
70
1.29
0.37
1.1
1.1
—
—
—
0
0
18
144
1.26
0.35
4.5
2.1
1.0
1.1
%
0.24
18
144
6
47
1.28
0.32
1.2
1.3
223.0
415.5
pmol/l
—
6
35
7
53
1.33
0.31
1.0
1.1
—
—
—
0
0
28
240
1.18
0.31
2.4
2.2
5.5
5.5
ug/l
0.01
21
211
7
54
1.30
0.30
1.0
1.1
—
—
—
0
0
10
75
1.34
0.30
1.3
1.8
—
—
—
0
0
13
163
0.79
0.30
1.2
1.5
—
—
—
0
0
8
108
0.74
0.29
1.3
1.4
—
—
—
0
0
17
140
1.22
0.28
1.0
1.1
—
—
—
0
0
17
141
1.21
0.26
1.2
1.3
—
—
—
0
0
113
1194
0.93
0.25
1.8
1.7
1.3
1.4
mmol/l
0.39
103
1028
57
524
1.10
0.24
2.7
1.8
28.7
29.5
s
0.56
57
507
10
79
1.27
0.22
1.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
15
129
1.17
0.17
1.3
1.2
—
—
—
0
0
7
63
1.11
0.17
1.3
1.2
—
—
—
0
0
423
4186
1.06
0.17
15.6
12.3
39.6
39.5
%
0.12
323
3221
8
68
1.18
0.16
1.3
1.1
117.3
120.6
%
—
8
61
36
390
0.92
0.16
4.0
3.9
3.4
8.5
ug/l
1.86
29
317
8
72
1.11
0.16
1.9
1.3
—
—
—
0
0
8
72
1.11
0.16
1.9
1.3
—
—
—
0
0
24
261
0.92
0.12
2.2
2.1
238.5
3873.0
u/l
—
7
111
119
1159
1.03
0.10
5.5
3.7
0.0
0.0
estimate
0.80
34
425
18
197
0.91
0.10
1.7
1.6
—
—
—
0
0
5
45
1.11
0.10
1.0
1.2
—
—
—
0
0
5
45
1.11
0.10
1.0
1.2
—
—
—
0
0
5
46
1.09
0.09
1.0
1.2
—
—
—
0
0
5
46
1.09
0.09
1.0
1.2
—
—
—
0
0
5
46
1.09
0.09
1.0
1.2
—
—
—
0
0
174
1708
1.03
0.09
4.6
3.5
—
—
—
0
0
10
113
0.88
0.08
1.1
1.2
3.2
3.7
mmol/l
—
10
102
7
66
1.06
0.08
1.4
1.5
—
—
—
0
0
46
477
0.96
0.06
1.7
1.6
—
—
—
0
0
436
4342
1.03
0.05
5.6
5.2
1.8
2.1
mu/l
0.58
398
4049
14
150
0.93
0.04
2.4
2.0
3.0
5.6
iu/l
—
7
56
10
92
1.09
0.03
2.0
1.5
—
—
—
0
0
14
132
1.06
0.02
5.1
3.2
44.0
49.6
%
0.44
14
132
44
448
0.98
0.01
1.2
1.2
105.3
150.5
iu/ml
0.57
15
197
35
344
1.02
0.00
5.1
7.2
0.8
1.5
mmol/l
0.58
23
275
10
96
1.04
0.00
2.0
1.5
—
—
—
0
0
17
174
0.98
0.00
1.7
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
18.3
—
0
8
5
49
1.02
0.00
1.6
1.5
—
—
—
0
0
5
52
0.96
0.00
1.4
1.8
7.2
7.1
mmol/l
—
5
30
0
8
0.00
0.00
0.0
2.4
—
1.2
—
0
8
8
80
1.00
0.00
3.0
2.1
13.1
13.2
%
—
8
80
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
29.7
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint N14_VAGINAL_LSIL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_VAGINAL_LSIL | 1.229 [1.05, 1.44] | 0.012 |
| Birth year | 1.0 [0.99, 1.01] | 0.998 |
During the follow-up period (1.1.1998 — 31.12.2019), 199 out of 2071 females with N14_VAGINAL_LSIL died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_VAGINAL_LSIL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.104% | No data |
| 5 | 0.814% | No data |
| 10 | 2.011% | No data |
| 15 | 4.023% | No data |
| 20 | 7.318% | No data |
Relationships between endpoints
↥Index endpoint: N14_VAGINAL_LSIL – LSIL lesion of the vagina
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data