No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleonly females |
293218 |
2. Check conditionsNone |
293218 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
572 |
4. Check minimum number of eventsNone |
572 |
5. Include endpointsNone |
572 |
6. Filter based on genotype QC (FinnGen only) |
551 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Similar endpoints
↥List of similar endpoints to
LSIL lesion of the vagina
based on the number of shared cases.
Similar with more cases:
- All dysplastic lesions of the vagina
- Other noninflammatory disorders of vagina
- LSIL lesion of the cervix uteri, vagina or vulva
- All dysplastic lesions of the cervix uteri, vagina or vulva
- Noninflammatory disorders of female genital tract
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2429 | 2429 | - |
| Only index persons | 2363 | 2363 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.07 | - |
| Only index persons | 0.09 | 0.09 | - |
| Median age at first event (years) | |||
| Whole population | - | 50.78 | - |
| Only index persons | - | 50.56 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 551 | 551 | - |
| Unadjusted period prevalence (%) | 0.20 | 0.20 | - |
| Median age at first event (years) | 52.54 | 52.54 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 572
- Matched controls
- 5720
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
34.2
307.7
440
508
N89.0
ICD-10 Finland
Mild vaginal dysplasia
+∞
307.7
572
*
LEB00
NOMESCO Finland
Biopsy of vagina
143.0
307.7
319
50
ULA02
NOMESCO Finland
Kolposcopy
61.2
307.7
490
509
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
195.7
299.5
146
10
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
15.6
254.2
371
606
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
16.1
247.9
285
332
N87.0
ICD-10 Finland
Mild cervical dysplasia
26.4
240.6
183
100
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
21.2
173.1
141
87
A63.0
ICD-10 Finland
Anogenital (venereal) warts
18.1
170.4
152
112
LDA10
NOMESCO Finland
Curettage of cervix uteri
11.1
132.7
166
204
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
11.4
130.3
157
183
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
20.5
122.4
98
57
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
273.9
72.1
72
*
N90.0
ICD-10 Finland
Mild vulvar dysplasia
108.2
62.4
67
7
N87.1
ICD-10 Finland
Moderate cervical dysplasia
10.0
57.9
70
79
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
17.8
55.3
46
28
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
11.0
50.3
56
56
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
162.5
43.4
45
*
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
449.4
42.8
42
*
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
7.2
39.5
62
95
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.5
25.6
303
1772
D06BB10
ATC
imiquimod; topical
4.7
25.5
63
147
L04AX01
ATC
azathioprine; systemic
5.5
24.7
50
98
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
65.2
22.0
25
*
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
22.5
21.0
30
14
G01AA10
ATC
clindamycin; vaginal
2.5
21.0
178
877
ZXC10
NOMESCO Finland
Use of laser
6.4
19.6
33
54
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
31.1
16.2
21
7
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
39.2
15.5
19
5
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.0
13.4
381
2857
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.5
12.4
88
391
D06BB04
ATC
podophyllotoxin; topical
3.0
11.2
53
191
LEB10
NOMESCO Finland
Excision of lesion of vagina
15.9
10.9
17
11
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
28.6
10.8
14
5
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.7
9.9
57
229
X86
ICPC
Abnormal cervix smear
7.3
9.6
22
31
LCA06
NOMESCO Finland
Biopsy of endometrium
2.0
9.5
120
671
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
8.5
9.1
19
23
ZXC00
NOMESCO Finland
Use of diathermy
9.6
8.3
16
17
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.0
8.3
104
579
ULC02
NOMESCO Finland
Hysteroscopy
2.5
7.9
51
216
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
15.3
7.7
12
8
P01BA02
ATC
hydroxychloroquine; oral
2.2
7.7
68
331
L04AD02
ATC
tacrolimus; systemic
10.2
7.6
14
14
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.2
7.4
66
323
R87.0
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of enzymes
20.3
7.2
10
5
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
7.1
228
1659
N87.9
ICD-10 Finland
Dysplasia of cervix uteri, unspecified
12.4
6.6
11
9
L04AA06
ATC
mycophenolic acid; systemic
5.4
6.5
18
34
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.9
6.5
29
102
M05BA04
ATC
alendronic acid; oral
2.3
6.4
50
231
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
2.4
6.4
42
180
127
Kela drug reimbursment
Transplant complication
6.7
6.4
15
23
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.7
6.3
156
1057
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.5
6.3
40
169
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
5.4
6.2
17
32
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
12.7
6.1
10
8
XG410
NOMESCO Finland
Flow-volume spirometry
3.1
6.0
25
84
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
6.0
199
1445
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
77
33
26.81
108.96
3.8
1.6
—
—
—
0
0
373
1414
5.71
92.01
2.9
1.4
—
—
—
0
0
144
311
5.85
66.27
2.7
1.5
—
—
—
0
0
131
694
2.15
12.25
2.0
1.8
—
—
—
0
0
96
470
2.25
10.83
1.7
1.7
—
—
—
0
0
135
759
2.02
10.64
2.2
2.0
—
—
—
0
0
79
369
2.32
9.93
1.7
1.6
—
—
—
0
0
105
575
2.01
8.78
3.9
3.9
32.16
32.97
%
0.30
63
393
439
3703
1.80
7.99
5.5
4.0
11.82
11.05
mm/h
0.71
405
3444
24
76
3.25
6.36
2.2
1.7
—
—
—
0
0
161
1136
1.58
5.41
2.6
2.0
—
—
—
0
0
37
163
2.36
5.33
4.1
1.6
0.19
0.24
g/l
3.01
37
154
38
170
2.32
5.29
4.1
1.5
1.02
1.22
g/l
4.19
38
160
252
1970
1.50
5.25
6.9
4.9
1.22
1.22
mmol/l
0.14
220
1804
32
134
2.47
5.15
2.5
2.3
1.47
1.48
g/l
0.01
27
113
24
87
2.84
5.10
2.8
3.9
40.35
23.62
mg/l
0.73
24
69
24
87
2.84
5.10
2.8
3.9
33.09
37.81
mg/l
0.22
24
71
39
181
2.24
5.00
3.6
1.8
—
—
—
0
0
274
2202
1.47
4.86
8.0
5.6
1.22
1.22
mmol/l
0.14
232
1875
15
34
4.50
4.77
1.3
1.2
—
—
—
0
0
235
1840
1.47
4.72
5.7
4.0
36.88
36.24
g/l
1.18
217
1728
40
193
2.15
4.68
1.4
1.7
—
—
—
0
0
52
277
1.96
4.68
11.7
7.2
7.51
7.98
mmol/l
0.26
47
262
85
531
1.71
4.58
6.5
5.0
—
—
—
0
0
420
3697
1.51
4.52
10.4
6.7
75.20
75.48
u/l
0.06
398
3467
21
78
2.76
4.30
13.5
5.4
593.00
164.78
iu/ml
—
7
9
36
173
2.15
4.27
2.1
1.8
—
—
—
0
0
100
666
1.61
4.21
3.1
2.3
0.94
1.19
e6/l
0.31
59
352
186
1422
1.46
4.11
3.4
2.3
56.75
56.72
u/l
0.00
177
1312
286
2374
1.41
3.98
9.5
5.6
30.44
29.33
%
1.09
266
2230
12
27
4.52
3.95
1.8
2.4
824.33
537.82
e6/l
0.91
12
22
506
4689
1.69
3.91
11.5
10.2
85.45
85.75
ml/min/173m2
0.11
417
3803
283
2352
1.40
3.87
9.2
5.3
55.47
56.51
%
0.81
263
2207
32
153
2.16
3.86
1.6
1.2
15.89
2.09
u/ml
—
7
18
369
3214
1.42
3.82
5.5
4.1
—
1282.59
—
0
44
331
2833
1.40
3.77
12.4
8.5
3.69
3.89
e9/l
1.27
297
2491
32
157
2.10
3.63
1.6
1.2
17.29
15.96
u/ml
—
8
32
222
1798
1.38
3.42
1.9
1.9
99.01
98.81
pmol/l
0.02
105
892
13
37
3.57
3.42
1.4
1.4
—
—
—
0
0
32
161
2.05
3.41
1.9
1.7
—
—
—
0
0
91
626
1.54
3.32
3.2
2.5
4.45
4.69
e6/l
0.07
49
314
75
496
1.59
3.25
4.6
2.3
5.21
5.85
umol/l
0.29
67
427
19
78
2.49
3.25
1.7
1.3
119.67
125.90
u/ml
—
6
20
16
62
2.63
3.07
1.3
1.3
—
—
—
0
0
8
16
5.05
3.06
1.4
1.1
—
—
—
0
0
8
16
5.05
3.06
1.0
1.9
—
—
—
0
0
8
16
5.05
3.06
1.4
1.1
—
—
—
0
0
8
16
5.05
3.06
1.0
1.9
—
—
—
0
0
72
479
1.58
3.05
8.9
4.3
1.04
1.04
mmol/l
0.07
65
438
7
12
5.89
3.03
3.1
2.4
43.29
56.30
ug/l
—
7
12
88
615
1.51
2.99
1.8
1.8
—
—
—
0
0
16
63
2.58
2.98
1.3
1.3
—
—
—
0
0
16
63
2.58
2.98
1.3
1.3
—
—
—
0
0
21
95
2.26
2.93
1.5
1.2
—
—
—
0
0
8
17
4.76
2.93
1.4
1.1
—
—
—
0
0
8
17
4.76
2.93
1.4
1.1
—
—
—
0
0
507
4767
1.56
2.89
4.5
4.1
5.63
5.73
mmol/l
1.48
450
4411
16
64
2.54
2.89
1.3
1.3
—
—
—
0
0
260
2203
1.33
2.86
2.7
2.3
78.72
77.35
nmol/l
0.34
226
2015
16
65
2.50
2.81
1.3
1.3
—
—
—
0
0
16
65
2.50
2.81
1.3
1.3
—
—
—
0
0
280
2409
1.32
2.72
8.4
5.5
9.38
9.50
umol/l
0.13
271
2279
546
5244
1.91
2.71
13.6
9.4
24.04
23.79
u/l
0.13
528
5080
146
1142
1.37
2.70
3.9
2.7
0.30
0.39
e6/l
0.37
110
848
144
1126
1.37
2.66
2.4
2.1
2.70
2.92
mg/l
0.73
115
963
22
106
2.12
2.66
1.3
1.3
—
—
—
0
0
25
128
2.00
2.59
1.5
1.2
44.34
27.45
u/ml
—
7
11
565
5525
2.85
2.58
22.8
17.1
39.63
39.76
%
0.29
539
5229
565
5531
2.76
2.45
22.7
17.1
4.39
4.44
e12/l
1.65
550
5399
565
5528
2.80
2.44
22.7
17.2
270.70
265.61
e9/l
1.06
551
5409
17
77
2.24
2.39
1.3
1.3
—
—
—
0
0
522
4976
1.56
2.38
14.6
12.0
139.66
139.74
mmol/l
0.29
500
4833
270
2341
1.29
2.37
2.8
2.3
—
—
—
0
0
12
46
2.64
2.37
1.8
1.7
24.40
15.85
mg/l
—
5
11
523
4989
1.56
2.36
14.9
12.0
3.91
3.92
mmol/l
0.33
500
4836
158
1276
1.33
2.34
1.3
1.3
0.67
1.94
u/ml
1.83
37
343
83
603
1.44
2.34
2.7
2.1
2.39
2.45
g/l
0.39
76
558
565
5532
2.74
2.31
22.8
17.2
132.14
132.98
g/l
1.03
557
5466
77
553
1.45
2.30
2.9
2.2
23.12
23.35
%
0.06
69
467
11
40
2.78
2.28
2.5
1.6
0.96
1.00
g/l
0.28
11
40
289
2548
1.27
2.15
5.2
3.9
6.37
6.43
mmol/l
0.14
265
2349
25
138
1.85
2.12
1.2
1.2
—
—
—
0
0
5
10
5.03
2.07
2.0
3.6
—
—
—
0
0
112
880
1.34
1.99
3.3
2.4
7.02
8.80
e6/l
0.34
103
791
86
649
1.38
1.97
3.0
2.2
12.91
13.96
umol/l
0.80
81
606
7
21
3.36
1.97
1.4
1.1
—
—
—
0
0
87
659
1.38
1.95
4.5
2.9
0.81
0.81
mmol/l
0.06
77
620
5
11
4.57
1.94
1.8
1.1
—
—
—
0
0
8
27
2.99
1.94
1.5
2.0
—
—
—
0
0
13
58
2.27
1.92
1.2
1.1
—
—
—
0
0
42
277
1.56
1.90
1.6
1.5
—
—
—
0
0
183
1546
1.27
1.89
3.1
3.0
18.19
26.18
ng/l
0.51
108
897
18
93
1.97
1.87
1.7
1.2
—
—
—
0
0
123
991
1.31
1.83
1.6
1.5
22.22
22.31
nmol/l
0.02
103
854
8
29
2.78
1.79
1.1
1.1
—
—
—
0
0
26
155
1.71
1.75
1.7
1.5
0.01
0.01
iu/ml
—
5
17
52
368
1.45
1.71
4.5
3.4
4.42
4.60
pmol/l
0.76
46
323
191
1638
1.25
1.71
5.4
2.9
29.31
28.02
u/l
0.41
185
1568
6
19
3.18
1.66
1.3
1.1
—
—
—
0
0
22
128
1.75
1.62
1.1
1.4
24.67
26.17
u/l
0.07
15
104
44
306
1.47
1.59
1.0
1.1
—
—
—
0
0
11
51
2.18
1.51
2.1
2.1
—
—
—
0
0
13
65
2.02
1.49
5.0
2.9
27.62
31.90
umol/l
0.51
13
58
45
320
1.44
1.47
1.8
1.5
—
—
—
0
0
9
38
2.39
1.46
1.0
1.1
312.67
289.97
mg/l
—
9
33
9
40
2.27
1.40
1.6
1.7
—
—
—
0
0
116
961
1.26
1.39
2.7
2.9
492.63
888.59
ng/l
2.13
100
810
5
121
0.41
1.39
1.4
1.5
—
—
—
0
0
9
41
2.21
1.37
1.0
1.0
—
—
—
0
0
365
3395
1.21
1.37
4.0
2.8
38.33
39.13
u/l
0.10
346
3217
30
439
0.67
1.37
2.9
3.0
—
—
—
0
0
97
788
1.28
1.37
2.4
2.6
2.42
2.44
mmol/l
1.40
85
702
15
83
1.83
1.32
1.1
1.2
2.80
6.28
u/ml
—
5
29
9
44
2.06
1.27
1.4
1.1
—
—
—
0
0
183
1608
1.20
1.25
2.9
3.3
2.35
2.36
mmol/l
0.68
154
1441
12
63
1.92
1.23
1.7
1.2
—
—
—
0
0
5
19
2.65
1.22
2.2
3.2
—
—
—
0
0
420
4402
0.83
1.19
17.5
13.6
14.95
14.58
%
0.65
411
4330
512
4963
1.30
1.14
15.5
11.3
19.27
19.38
mg/l
0.02
411
3780
7
30
2.35
1.12
1.3
1.1
—
—
—
0
0
5
21
2.39
1.09
1.2
1.6
115.20
71.24
nmol/24h
—
5
21
5
21
2.39
1.09
1.8
1.4
7.89
8.43
ug/l
—
5
21
88
728
1.25
1.09
1.6
1.7
1021.54
1203.89
nmol/l
1.31
66
547
7
34
2.07
1.03
2.1
1.6
—
—
—
0
0
507
4920
1.27
1.03
4.3
4.1
4.94
4.89
mmol/l
0.55
465
4627
52
407
1.31
1.00
1.7
1.8
—
—
—
0
0
46
354
1.33
1.00
5.0
3.0
94.72
73.97
ng/l
0.56
41
318
151
1331
1.18
0.99
2.7
2.0
93.76
190.26
u/l
1.31
144
1259
0
29
0.00
0.98
0.0
1.3
—
—
—
0
0
7
36
1.96
0.97
2.3
1.4
—
—
—
0
0
7
36
1.96
0.97
2.3
1.4
—
—
—
0
0
7
36
1.96
0.97
2.3
1.4
—
—
—
0
0
9
50
1.81
0.97
1.3
1.2
—
—
—
0
0
9
50
1.81
0.97
1.3
1.2
—
—
—
0
0
0
31
0.00
0.96
0.0
1.5
—
—
—
0
0
21
141
1.51
0.96
3.4
2.0
198.30
167.76
%
1.08
21
135
6
27
2.23
0.93
4.3
1.9
94.50
104.07
%
—
6
27
51
403
1.29
0.93
1.6
1.7
—
—
—
0
0
10
55
1.83
0.92
1.1
1.1
101.70
98.10
%
—
10
50
261
2414
1.15
0.90
4.3
3.4
0.00
0.00
estimate
-0.00
40
496
59
477
1.26
0.90
2.4
2.1
393.98
370.65
nmol/l
0.45
52
443
11
63
1.76
0.90
1.2
1.0
—
—
—
0
0
39
298
1.33
0.90
1.7
2.6
66.46
67.40
g/l
0.30
34
272
261
2422
1.14
0.85
5.8
4.7
0.00
0.00
estimate
0.50
41
474
31
232
1.36
0.83
1.5
1.3
127.01
233.38
miu/ml
0.96
14
115
143
1274
1.16
0.82
3.5
2.9
6.56
6.98
mmol/l
0.77
122
1097
104
905
1.18
0.80
1.5
1.6
460.51
36788006.60
pmol/l
1.31
90
772
9
148
0.60
0.80
1.6
1.7
—
—
—
0
0
27
199
1.37
0.79
1.6
1.8
—
—
—
0
0
8
48
1.68
0.79
1.4
1.5
—
—
—
0
0
8
48
1.68
0.79
1.4
1.5
—
—
—
0
0
0
26
0.00
0.78
0.0
1.3
—
—
—
0
0
0
26
0.00
0.78
0.0
1.1
—
119.84
—
0
19
7
125
0.55
0.78
2.3
1.6
—
—
—
0
0
0
28
0.00
0.76
0.0
1.1
—
—
—
0
0
10
59
1.71
0.76
2.5
1.7
35.81
70.26
u/ml
—
10
59
131
1168
1.16
0.75
1.8
1.7
0.96
0.90
mg/l
0.12
91
889
5
24
2.09
0.74
2.6
2.8
42200.00
35737.71
ug/l
—
5
24
5
24
2.09
0.74
2.8
3.8
5329.00
711.17
u/ml
—
5
24
502
4898
1.20
0.74
4.4
4.0
1.61
1.59
mmol/l
0.33
452
4585
7
39
1.80
0.72
2.6
2.0
—
—
—
0
0
7
39
1.80
0.72
2.1
1.5
—
—
—
0
0
261
2443
1.13
0.71
4.3
3.4
0.00
0.01
estimate
0.80
41
463
117
1039
1.16
0.71
1.3
1.3
12.20
12.11
u/ml
0.00
44
420
5
26
1.93
0.70
1.0
1.1
—
—
—
0
0
379
3631
1.13
0.69
3.4
3.4
—
—
—
0
0
68
578
1.20
0.69
2.1
1.5
1.24
1.33
%
0.84
58
516
12
77
1.57
0.69
1.2
1.2
—
—
—
0
0
28
214
1.32
0.68
4.4
2.9
1.45
1.85
mmol/l
0.25
22
164
5
28
1.79
0.66
3.2
1.5
29.97
25.79
ug/l
—
5
28
38
305
1.26
0.65
5.5
3.1
5.77
5.85
kpa
0.20
38
300
14
95
1.49
0.64
2.7
2.2
—
—
—
0
0
66
766
0.84
0.63
2.6
3.2
220.67
269.74
ng/l
0.11
42
490
11
71
1.56
0.62
1.2
1.3
—
—
—
0
0
5
30
1.67
0.61
1.2
1.6
1.43
1.03
promille
—
5
22
0
22
0.00
0.59
0.0
1.4
—
—
—
0
0
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
0
22
0.00
0.59
0.0
1.4
—
—
—
0
0
458
4459
1.14
0.58
5.1
4.9
37.61
38.50
mmol/mol
1.97
413
4173
6
35
1.72
0.58
1.0
1.0
—
—
—
0
0
509
4992
1.18
0.58
4.7
4.5
2.93
2.90
mmol/l
0.31
459
4663
117
1056
1.14
0.57
1.4
1.3
22.27
29.44
iu/ml
0.62
33
354
29
362
0.79
0.57
1.2
1.5
—
—
—
0
0
20
150
1.35
0.56
1.0
1.1
—
—
—
0
0
29
360
0.80
0.54
3.7
3.5
1.23
1.23
mmol/l
0.45
29
314
20
151
1.34
0.54
1.2
1.3
—
—
—
0
0
35
423
0.82
0.52
1.4
1.3
33.84
28.80
iu/l
0.31
27
361
435
4231
1.12
0.52
4.6
4.4
14.52
14.46
pmol/l
0.18
402
3928
46
389
1.20
0.52
2.6
2.1
71.33
73.66
ml/min/173m2
0.13
15
149
6
40
1.51
0.51
1.5
1.3
—
—
—
0
0
20
153
1.32
0.51
1.5
1.4
352.64
304.18
ug/g
0.48
14
86
257
2440
1.10
0.50
3.3
2.8
88.42
78.07
ug/l
0.61
237
2287
131
1205
1.11
0.48
4.0
3.6
18.61
8.99
mg/mmol
0.59
67
709
7
47
1.50
0.47
1.0
1.2
—
—
—
0
0
7
47
1.50
0.47
1.0
1.2
—
—
—
0
0
481
4713
1.13
0.47
3.9
3.6
1.23
1.23
mmol/l
0.07
427
4386
7
48
1.46
0.47
1.0
1.2
—
—
—
0
0
7
48
1.46
0.47
1.0
1.2
—
—
—
0
0
7
48
1.46
0.47
1.0
1.2
—
—
—
0
0
8
119
0.67
0.46
1.3
1.4
—
—
—
0
0
8
121
0.66
0.46
1.1
1.5
—
—
—
0
0
123
1131
1.11
0.45
4.0
2.3
309.60
4693.11
umol/l
3.88
107
1004
39
330
1.20
0.45
1.9
1.4
—
—
—
0
0
113
1035
1.11
0.45
5.4
3.6
1.02
1.02
kg/l
—
8
149
7
50
1.40
0.45
1.0
1.1
—
—
—
0
0
10
69
1.46
0.44
2.0
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
6.3
—
—
—
0
0
8
59
1.36
0.41
1.3
1.5
—
—
—
0
0
20
249
0.80
0.41
1.3
1.4
—
—
—
0
0
11
79
1.40
0.41
1.2
1.2
—
—
—
0
0
18
227
0.79
0.41
1.3
1.5
—
—
—
0
0
17
216
0.78
0.41
1.2
1.4
—
—
—
0
0
17
216
0.78
0.41
1.2
1.4
—
—
—
0
0
17
216
0.78
0.41
1.2
1.4
—
—
—
0
0
17
216
0.78
0.41
1.2
1.4
—
—
—
0
0
18
141
1.29
0.40
1.2
1.7
—
—
—
0
0
10
71
1.42
0.39
2.0
1.5
—
—
—
0
0
10
71
1.42
0.39
2.0
1.5
—
—
—
0
0
126
1171
1.10
0.39
1.6
1.5
—
—
—
0
0
28
234
1.21
0.38
1.5
1.5
—
—
—
0
0
49
554
0.87
0.37
1.7
1.6
—
—
—
0
0
14
179
0.78
0.36
1.2
1.5
—
—
—
0
0
5
77
0.65
0.36
1.0
1.6
—
—
—
0
0
35
302
1.17
0.35
9.1
6.1
1.33
1.21
mmol/l
0.17
35
295
20
163
1.24
0.34
1.2
1.2
—
—
—
0
0
20
164
1.23
0.33
1.2
1.2
—
—
—
0
0
11
83
1.33
0.32
1.1
1.1
—
—
—
0
0
11
84
1.32
0.30
1.1
1.0
—
—
—
0
0
19
157
1.22
0.30
4.3
2.3
0.65
0.66
%
0.03
19
157
8
107
0.74
0.29
3.4
4.1
60.13
58.77
%
—
8
107
7
57
1.23
0.29
1.0
1.1
—
—
—
0
0
10
76
1.32
0.28
1.2
1.1
120.00
119.49
%
—
10
69
8
62
1.29
0.28
1.0
1.1
—
—
—
0
0
8
67
1.20
0.26
1.3
1.1
—
—
—
0
0
30
263
1.15
0.26
2.5
2.2
5.38
5.72
ug/l
0.06
23
231
189
1819
1.06
0.24
11.0
8.9
1.10
1.12
inr
0.18
40
581
5
38
1.32
0.23
1.4
1.1
—
—
—
0
0
5
38
1.32
0.23
1.0
1.1
25.70
27.67
nmol/l
—
5
28
19
162
1.18
0.23
4.3
2.3
1.11
1.09
%
0.04
19
162
5
40
1.25
0.22
1.0
1.0
—
—
—
0
0
5
41
1.22
0.22
1.0
1.5
—
—
—
0
0
19
220
0.86
0.22
1.7
1.6
—
—
—
0
0
39
429
0.90
0.21
3.8
3.9
3.19
8.29
ug/l
2.09
32
347
0
10
0.00
0.21
0.0
1.0
—
16.40
—
0
10
8
105
0.76
0.21
2.9
3.7
4.13
4.40
e9/l
—
8
105
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
14
164
0.85
0.18
2.4
1.9
2.99
5.54
iu/l
—
7
59
7
58
1.21
0.18
1.0
1.1
—
—
—
0
0
133
1281
1.05
0.17
5.2
3.6
0.00
0.01
estimate
1.08
40
478
10
83
1.21
0.15
1.3
1.8
—
—
—
0
0
9
79
1.14
0.15
1.8
1.3
—
—
—
0
0
9
79
1.14
0.15
1.8
1.3
—
—
—
0
0
10
85
1.18
0.12
2.6
2.0
13.00
13.25
%
—
10
85
16
146
1.10
0.08
4.8
3.4
42.88
49.52
%
0.61
16
146
129
1317
0.97
0.08
1.8
1.6
1.31
1.35
mmol/l
0.18
117
1136
192
1891
1.02
0.07
4.4
3.4
—
—
—
0
0
484
4817
1.03
0.07
5.5
5.1
1.77
2.05
mu/l
0.58
443
4496
47
488
0.96
0.07
1.2
1.2
96.28
146.27
iu/ml
0.76
17
210
27
284
0.95
0.06
2.1
2.1
238.54
3636.13
u/l
—
7
120
60
589
1.02
0.03
2.7
1.8
28.56
29.39
s
0.62
60
569
15
142
1.06
0.02
1.3
1.2
—
—
—
0
0
10
94
1.06
0.01
2.0
1.5
—
—
—
0
0
12
123
0.98
0.00
1.2
1.1
0.60
2.33
u/ml
—
5
60
38
384
0.99
0.00
7.5
7.0
0.60
1.33
mmol/l
0.70
27
312
10
99
1.01
0.00
2.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
29.70
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
12
120
1.00
-0.00
1.1
1.2
3.34
3.66
mmol/l
1.17
12
109
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
7
69
1.01
-0.00
1.4
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
19
190
1.00
-0.00
1.6
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.2
—
1.21
—
0
9
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
51
0.98
-0.00
1.6
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint N14_VAGINAL_LSIL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_VAGINAL_LSIL | 1.229 [1.05, 1.44] | 0.012 |
| Birth year | 1.0 [0.99, 1.01] | 0.998 |
During the follow-up period (1.1.1998 — 31.12.2019), 199 out of 2071 females with N14_VAGINAL_LSIL died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_VAGINAL_LSIL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.104% | No data |
| 5 | 0.814% | No data |
| 10 | 2.011% | No data |
| 15 | 4.023% | No data |
| 20 | 7.318% | No data |
Relationships between endpoints
↥Index endpoint: N14_VAGINAL_LSIL – LSIL lesion of the vagina
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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