HSIL lesion of the cervix uteri

N14_CERVICAL_HSIL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D06, N87.1, N87.2
  • Hospital discharge: ICD-9 6221B|6221C|2331A
  • Cause of death: ICD-10 D06, N87.1, N87.2
  • Cause of death: ICD-9 6221B|6221C|2331A

2 out of 7 registries used, show all original rules.

8207

4. Check minimum number of events

None

8207

5. Include endpoints

None

8207

6. Filter based on genotype QC (FinnGen only)

8207

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Similar endpoints

List of similar endpoints to HSIL lesion of the cervix uteri based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 53171 53171 -
Only index persons 51989 51989 -
Unadjusted period prevalence (%)
Whole population 1.52 1.52 -
Only index persons 1.91 1.91 -
Median age at first event (years)
Whole population - 34.59 -
Only index persons - 34.40 -

-FinnGen-

Key figures

All Female Male
Number of individuals 8207 8207 -
Unadjusted period prevalence (%) 2.80 2.80 -
Median age at first event (years) 35.09 35.09 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
7298
Matched controls
72980
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LDA10
NOMESCO Finland
Curettage of cervix uteri
19.2
323.0
2427
1850
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
38.4
323.0
5593
5736
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
9036.7
323.0
3796
8
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
+∞
323.0
381
*
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
26.1
323.0
4218
3641
N87.0
ICD-10 Finland
Mild cervical dysplasia
9.0
323.0
1040
1325
N87.1
ICD-10 Finland
Moderate cervical dysplasia
16384.0
323.0
3559
*
ULA02
NOMESCO Finland
Kolposcopy
42.2
323.0
5673
5571
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
406.1
323.0
2289
82
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
14.6
323.0
4556
7471
C539, 6666, 0
ICD-O-3
NA
216.4
323.0
1119
61
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
137.3
323.0
4864
1044
ZXC00
NOMESCO Finland
Use of diathermy
39.8
301.8
385
102
8070/2-C53.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of cervix uteri
83.5
283.2
319
40
A63.0
ICD-10 Finland
Anogenital (venereal) warts
5.1
273.7
950
2087
D06.1
ICD-10 Finland
Carcinoma in situ: Exocervix
+∞
254.7
243
*
8326
FHL
Batch conization
62.0
229.0
269
45
6221C
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI GRAVIS]
+∞
217.8
208
*
6221B
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI MODERATA]
+∞
184.1
176
*
LEB00
NOMESCO Finland
Biopsy of vagina
8.2
183.4
428
547
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.0
168.0
3672
24614
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
9.8
159.4
334
354
8140/2-C53.9
ICD-O-3
Adenocarcinoma in situ, NOS, of cervix uteri
310.8
149.2
151
5
G01AA10
ATC
clindamycin; vaginal
2.0
130.5
2013
11453
8077/2-C53.1
ICD-O-3
Squamous intraepithelial neoplasia, high grade of exocervix
265.2
127.5
130
5
D06.9
ICD-10 Finland
Carcinoma in situ: Cervix, unspecified
+∞
123.3
118
*
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
6.0
117.7
340
585
N87.9
ICD-10 Finland
Dysplasia of cervix uteri, unspecified
18.0
117.1
186
106
2331A
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Cervix uteri
+∞
99.2
95
*
LDC00
NOMESCO Finland
Conisation of cervix uteri using knife
82.0
72.1
81
10
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
3.8
70.9
314
844
R87.2
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of other drugs, medicaments and biological substances
26.8
70.5
98
37
X86
ICPC
Abnormal cervix smear
5.2
70.5
227
445
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
9.2
63.1
135
149
R87.1
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of hormones
33.2
62.4
82
25
LCA06
NOMESCO Finland
Biopsy of endometrium
1.8
62.1
1270
7683
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
10.2
61.9
125
124
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
59.4
2361
17135
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.5
58.0
487
2028
C53.11
ICD-10 Finland
Squamous cell carcinoma and exocervix
20.5
52.6
79
39
P01AB01
ATC
metronidazole; oral, rectal
1.5
49.8
3112
24650
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
15.3
47.5
79
52
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.6
46.7
1272
8296
8070/3-C53.9
ICD-O-3
Squamous cell carcinoma, NOS, of cervix uteri
24.8
41.8
59
24
D06BB04
ATC
podophyllotoxin; topical
1.9
41.1
617
3323
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
19.8
40.4
61
31
C53.01
ICD-10 Finland
Squamous cell carcinoma of the endocervix
17.3
37.9
60
35
N89.0
ICD-10 Finland
Mild vaginal dysplasia
7.6
36.7
87
115
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1.6
36.6
1133
7591
TLC02
NOMESCO Finland
Simple extraction of IUD
1.9
32.8
540
2997
8140/2-C53.0
ICD-O-3
Adenocarcinoma in situ, NOS, of endocervix
+∞
32.3
31
*
WX110
NOMESCO Finland
Local anesthesy
1.3
29.5
4960
44666
C53.02
ICD-10 Finland
Adenocarcinoma of the endocervix
12.8
29.2
52
41
8140/2-C53.1
ICD-O-3
Adenocarcinoma in situ, NOS, of exocervix
150.6
28.6
30
*
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
11.9
28.3
52
44
O34.4
ICD-10 Finland
Maternal care for other abnormalities of cervix
8.8
28.3
61
70
SPAT1193
SPAT
Pap smear
1.5
28.3
1212
8694
N07BA03
ATC
varenicline; oral
2.0
28.2
385
1997
N87
ICD-10 Finland
Dysplasia of cervix uteri
17.0
27.9
44
26
N90.0
ICD-10 Finland
Mild vulvar dysplasia
8.2
27.2
61
75
R2110
NOMESCO Finland
Giving the first information
1.7
27.2
630
3892
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
26.8
2027
16101
R87.9
ICD-10 Finland
Abnormal findings in specimens from female genital organs, unspecified abnormal finding
8.7
26.4
57
66
LDB00
NOMESCO Finland
Excision of lesion of cervix uteri
3.2
26.3
141
445
8076/3-C53.9
ICD-O-3
Squamous cell carcinoma, microinvasive of cervix uteri
70.1
24.8
28
*
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
10.3
24.4
48
47
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.4
23.8
1155
8463
D06BB10
ATC
imiquimod; topical
2.0
23.6
318
1641
X23
ICPC
Fear sexually transm dis female
1.6
23.5
591
3728
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.5
23.4
798
5429
N76.0
ICD-10 Finland
Acute vaginitis
1.6
23.0
689
4548
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
15.1
21.9
36
24
X92
ICPC
Chlamydia infection genital female
2.6
21.6
157
605
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
3.8
21.4
92
246
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
2.1
21.1
251
1234
LCH11
NOMESCO Finland
Pharmacologic abortion
1.6
21.0
522
3282
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.3
20.9
1686
13425
8140/3-C53.9
ICD-O-3
Adenocarcinoma, NOS, of cervix uteri
16.6
20.9
33
20
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
2.3
20.4
183
792
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
7.2
19.2
46
64
SPAT1283
SPAT
Restricted health certificate
1.3
18.8
1780
14475
8325
FHL
Coagulation, cryo or laser in anesthesia or operating room
6.0
18.5
51
86
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
1.8
18.5
304
1688
N02AX02
ATC
tramadol; systemic, rectal
1.3
17.9
2095
17499
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.5
17.9
594
4009
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
17.3
368
2217
K05.31
ICD-10 Finland
Periodontitis pronounced
1.7
17.1
368
2220
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
2.2
17.0
170
774
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
1.5
16.7
546
3671
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
1.3
16.6
1404
11210
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
1.9
16.4
228
1194
M03BX02
ATC
tizanidine; oral
1.2
16.4
4365
39905
SPAT1308
SPAT
Sexual health counselling
1.3
16.2
1408
11279
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
1.9
16.2
256
1404
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.4
16.2
905
6768
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
1.7
16.0
322
1909
R87.3
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of substances chiefly nonmedicinal as to source
33.4
15.7
20
6
8010/2-C53.9
ICD-O-3
Carcinoma in situ, NOS, of cervix uteri
+∞
15.6
15
*
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
15.5
5154
48100
G01AF01
ATC
metronidazole; vaginal
1.4
15.4
731
5303
0781C
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Viral warts[CONDYLOMA ACCUMINATUM]
3.4
15.2
72
211
Z72.0
ICD-10 Finland
Tobacco use
2.2
15.1
155
717
LCD10
NOMESCO Finland
Vaginal hysterectomy
1.9
15.0
234
1278
Z30.4
ICD-10 Finland
Surveillance of contraceptive drugs
1.4
15.0
714
5187
N02BE01
ATC
paracetamol; systemic, rectal
1.3
14.9
5729
54205
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
14.9
2490
21581
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
4.3
14.8
54
126
M54.5
ICD-10 Finland
Low back pain
1.2
14.7
2128
18143
W11
ICPC
Contraception oral
1.4
14.5
923
7048
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.5
14.3
527
3638
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
14.2
1420
11564
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.5
14.2
549
3826
LCD31
NOMESCO Finland
Radical laparoscopic hysterectomy
9.7
14.2
28
29
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
14.0
2794
24617
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
14.0
175
882
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.3
13.1
1010
7930
EBA00
NOMESCO Finland
Extraction of tooth
1.2
13.1
1886
16030
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
13.0
6572
63548
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
1.7
12.9
287
1750
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
13.0
12.9
22
17
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.0
12.8
159
797
J01DB01
ATC
cefalexin; oral
1.2
12.6
5645
53588
N93.0
ICD-10 Finland
Postcoital and contact bleeding
2.6
12.5
90
349
J01CA08
ATC
pivmecillinam; oral
1.2
12.4
3454
31296
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
12.3
3342
30209
K02.1
ICD-10 Finland
Caries of dentine
1.2
12.2
4060
37367
R87.0
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of enzymes
6.7
12.2
30
45
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
1.2
12.1
1502
12537
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
11.9
3717
33976
D82
ICPC
Teeth/gum disease
1.2
11.9
2436
21413
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
1.7
11.8
263
1606
N06AX11
ATC
mirtazapine; oral
1.2
11.7
1857
15905
WX290
NOMESCO Finland
Other blockade of nerve
1.2
11.7
3352
30388
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
1.6
11.6
303
1932
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.2
11.5
1957
16883
X15
ICPC
Vaginal symptom/complaint other
1.6
11.3
326
2134
SPAT1312
SPAT
General health counselling
1.2
11.1
1981
17159
8070/3-C53.1
ICD-O-3
Squamous cell carcinoma, NOS, of exocervix
20.0
11.1
16
8
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.2
11.0
2471
21880
PJA01
NOMESCO Finland
Laparoscopic sentinel node excision
4.4
11.0
38
86
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
10.8
2438
21585
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
2.5
10.8
83
336
R74
ICPC
Upper respiratory infection acute
1.2
10.7
2364
20886
T36
ICD-10 Finland
Poisoning by systemic antibiotics
1.6
10.7
294
1901
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
2.2
10.6
100
449
SPAT1263
SPAT
Sampling
1.2
10.6
2645
23618
WX408
NOMESCO Finland
General anesthesy, balanced
1.2
10.3
1374
11538
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
1.7
10.2
189
1096
LBE20
NOMESCO Finland
Laparoscopic bilateral salpingectomy
1.8
10.1
158
872
W14
ICPC
Contraception female other
1.4
10.0
496
3625
8327
FHL
Amputation portionis and conization
40.1
10.0
12
*
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
9.9
3590
33014
N05CF01
ATC
zopiclone; oral
1.2
9.9
1503
12786
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.3
9.9
1026
8365
X85
ICPC
Cervical disease NOS
7.6
9.9
22
29
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.2
9.8
2338
20755
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
3.9
9.8
38
97
7950A
ICD-9 Finland
Nonspecific abnormal histological and immunological findings, Nonspecific abnormal Papanicolaou smear of cervix
8.7
9.8
20
23
J02AC01
ATC
fluconazole; systemic
1.2
9.7
3504
32185
C53.12
ICD-10 Finland
Adenocarcinoma of the exocervix
9.5
9.7
19
20
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
1.6
9.7
240
1514
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
9.6
4929
46572
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
1.4
9.6
383
2692
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.2
9.5
1239
10360
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
9.5
3576
32935
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
9.4
2175
19238
8077/2-C53.0
ICD-O-3
Squamous intraepithelial neoplasia, high grade of endocervix
+∞
9.4
9
*
D06.7
ICD-10 Finland
Carcinoma in situ: Other parts of cervix
+∞
9.4
9
*
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
9.3
2607
23430
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.2
9.3
1520
13018
M03BC01
ATC
orphenadrine (citrate); systemic
1.2
9.2
1608
13861
Z30.0
ICD-10 Finland
General counselling and advice on contraception
1.3
9.2
638
4927
T74.1
ICD-10 Finland
Physical abuse
1.8
9.0
139
762
LDA96
NOMESCO Finland
Other biopsy of cervix uteri
15.6
9.0
14
9
J01AA02
ATC
doxycycline; systemic
1.2
9.0
4997
47369
A03
ICPC
Fever
1.2
8.8
1112
9263
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
3.5
8.8
39
112
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
5.1
8.7
26
51
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
1.3
8.7
551
4200
Z30.2
ICD-10 Finland
Sterilization
1.3
8.6
854
6916
M01AE03
ATC
ketoprofen; systemic, rectal
1.2
8.4
1922
16953
M01AB05
ATC
diclofenac; systemic, rectal
1.2
8.3
4223
39619
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.2
8.3
1363
11666
LDA00
NOMESCO Finland
Dilatation of cervix uteri
2.3
8.2
70
304
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
0.8
8.1
818
9904
J01DA01
ATC
[U] cefalexin; systemic
1.2
8.0
4135
38776
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
2.5
8.0
59
235
21899
ICD-8 Finland
Uterine fibroma
0.2
7.9
7
368
WX002
NOMESCO Finland
Sedation and analgesia
1.3
7.8
794
6448
X29
ICPC
Genital sympt/compl female other
1.9
7.8
105
549
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
1.2
7.8
971
8069
J01FF01
ATC
clindamycin; systemic
1.2
7.8
1430
12365
SPAT1192
SPAT
Gynaecological examination
1.2
7.7
1072
9018
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.2
7.7
1188
10099
D11
ICPC
Diarrhoea
1.3
7.7
768
6229
C53.00
ICD-10 Finland
Malignant tumor of endocervix without histology
7.4
7.7
17
23
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.3
7.6
64
276
J05AB01
ATC
aciclovir; systemic
1.2
7.6
1302
11182
N88.2
ICD-10 Finland
Stricture and stenosis of cervix uteri
4.9
7.6
23
47
L04AX01
ATC
azathioprine; systemic
1.5
7.5
221
1460
O04.6
ICD-10 Finland
Medical abortion, complete or unspecified, complicated by delayed or excessive haemorrhage
1.8
7.5
118
656
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
2.3
7.4
62
268
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.1
7.4
4003
37567
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.3
7.3
584
4602
T810, N872
ICD-10 Finland
NA
+∞
7.3
7
*
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
1.5
7.3
236
1595
N06AX16
ATC
venlafaxine; oral
1.2
7.3
931
7759
LCH13
NOMESCO Finland
Vacuum aspiration from uterus after medically induced abortion
1.6
7.2
173
1086
X14
ICPC
Vaginal discharge
1.5
7.2
206
1350
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
0.8
7.2
392
5110
Z87.4
ICD-10 Finland
Personal history of diseases of the genitourinary system
2.0
7.1
81
401
LDC96
NOMESCO Finland
Other excision of cervix uteri
20.0
7.1
10
5
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.2
7.1
1548
13577
LDB10
NOMESCO Finland
Cryotherapy of cervix uteri
3.0
7.1
38
128
ZXC96
NOMESCO Finland
Robot assisted procedure
2.2
7.0
65
294
N76.1
ICD-10 Finland
Subacute and chronic vaginitis
1.6
7.0
174
1104
XLA10
NOMESCO Finland
NA
1.4
6.9
368
2726
R21
ICPC
Throat symptom/complaint
1.2
6.9
1576
13861
LCD30
NOMESCO Finland
Radical hysterectomy
6.3
6.9
17
27
X91
ICPC
Condylomata acuminata female
3.0
6.9
36
119
D10
ICPC
Vomiting
1.3
6.9
451
3456
L03
ICPC
Low back symptom/complaint
1.2
6.9
1385
12053
M54
ICD-10 Finland
Dorsalgia
1.3
6.9
674
5451
LDC10
NOMESCO Finland
Partial excision of cervix uteri
8.2
6.8
14
17
ZX040
NOMESCO Finland
Intracavity HDR radiotherapy
4.7
6.7
21
45
SXA20
NOMESCO Finland
Local application of medicine to mouth
1.3
6.7
397
3001
8070/3-C53.0
ICD-O-3
Squamous cell carcinoma, NOS, of endocervix
22.5
6.7
9
*
A02BC02
ATC
pantoprazole; systemic
1.1
6.7
3646
34131
N72
ICD-10 Finland
Inflammatory disease of cervix uteri
2.1
6.6
67
314
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
1.6
6.6
159
1000
N97.2
ICD-10 Finland
Female infertility of uterine origin
4.2
6.6
23
55
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
2.1
6.6
65
305
N05BA04
ATC
oxazepam; oral
1.2
6.6
1435
12570
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
6.6
1668
14797
M77.1
ICD-10 Finland
Lateral epicondylitis
1.3
6.5
469
3641
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.2
6.5
997
8459
H02AB06
ATC
prednisolone; systemic
1.1
6.5
2546
23298
P17
ICPC
Tobacco abuse
1.9
6.5
82
424
SAA02
NOMESCO Finland
Basic examination of mouth
1.1
6.5
4672
44495
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.3
6.4
604
4860
1390
FHL
Colposcopy
4.2
6.4
22
52
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.2
6.4
1662
14764
W12
ICPC
Contraception intrauterine
1.2
6.3
1053
9003
R51.80
ICD-10 Finland
Headache
1.2
6.3
991
8427
8111
FHL
Taking a biopsy from the mouth of the uterus at the operating room or under anesthesia (vulvabiopsia 8474, vaginabiopsia 8411)
4.4
6.3
21
48
8140/3-C53.0
ICD-O-3
Adenocarcinoma, NOS, of endocervix
8.1
6.3
13
16
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
1.8
6.3
93
508
4044
NOMESCO Finland
NA
5.5
6.3
17
31
SPAT1249
SPAT
Treatment-related counselling outside office
1.1
6.3
2514
23032
M01AH05
ATC
etoricoxib; oral
1.1
6.2
3616
33925
J01FA10
ATC
azithromycin; systemic
1.1
6.2
4174
39515
R05
ICPC
Cough
1.2
6.2
1253
10907
SPAT1301
SPAT
No procedures
1.2
6.1
1606
14267
TPH04
NOMESCO Finland
Cathetrisation of vein
1.2
6.1
872
7349
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
0.6
6.1
96
1556
R87.8
ICD-10 Finland
Abnormal findings in specimens from female genital organs, other abnormal findings
2.9
6.0
35
123
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
1.7
6.0
125
759
M79.6
ICD-10 Finland
Pain in limb
1.1
6.0
2004
18115
AA1AD
NOMESCO Finland
CT of head and brain
1.2
6.0
764
6363
Z09.9
ICD-10 Finland
Follow-up examination after unspecified treatment for other conditions
1.8
6.0
89
489

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1487
1766
10.06
307.65
2.3
1.5
—
—
—
0
0
4612
29962
2.23
267.21
2.7
1.9
—
—
—
0
0
899
4734
2.01
75.65
1.4
1.3
—
—
—
0
0
82
148
5.59
43.29
1.6
2.2
7.0
4.4
ug/l
0.18
54
84
5245
48479
1.23
16.73
4.2
3.9
—
—
—
0
0
1157
9025
1.33
16.53
1.3
1.2
—
—
—
0
0
5069
46717
1.22
16.51
4.0
3.9
1963.0
1858.5
e6/l
0.03
50
479
2798
24447
1.22
15.22
2.1
2.0
—
—
—
0
0
5428
50885
1.20
12.75
4.0
3.7
9.6
9.7
mm/h
0.30
5119
48062
7308
70716
1.31
12.37
11.0
10.1
18.8
18.2
mg/l
0.86
5643
54215
2448
21448
1.20
12.28
6.1
5.8
—
—
—
0
0
2457
21545
1.20
12.20
2.1
1.9
—
—
—
0
0
3868
35329
1.18
11.92
3.4
3.2
0.0
0.0
estimate
2.96
774
6967
6994
67376
1.26
11.80
10.3
9.7
3.9
3.9
mmol/l
0.37
6780
65466
3840
35094
1.18
11.64
4.5
4.4
0.0
0.0
estimate
0.00
790
7072
6967
67182
1.25
11.04
10.3
9.6
139.5
139.6
mmol/l
2.05
6768
65442
5133
48154
1.18
10.94
7.0
6.6
71.2
72.0
u/l
0.88
4833
45563
1001
8089
1.27
10.68
2.2
2.2
4224.9
5999.1
u/l
1.19
396
3346
3809
34936
1.17
10.67
3.3
3.2
0.0
0.0
estimate
0.04
763
6842
3723
34226
1.16
9.79
5.9
5.7
0.0
0.0
e9/l
0.43
3302
30322
2450
21808
1.18
9.75
3.3
3.2
58.2
74.4
e6/l
0.97
1572
14089
432
3174
1.38
9.06
4.0
2.5
—
—
—
0
0
3698
34104
1.15
9.04
5.9
5.6
0.5
0.5
e9/l
0.75
3301
30297
3478
32005
1.15
8.62
6.1
5.6
2.7
2.8
%
0.82
3262
29995
7527
73557
1.28
8.55
9.1
8.5
23.7
23.9
u/l
0.19
7321
71625
3690
34122
1.15
8.48
3.9
3.8
—
—
—
0
0
1804
15818
1.18
8.40
2.1
1.9
—
—
—
0
0
3489
32167
1.15
8.31
6.3
5.9
7.8
7.9
%
0.12
3298
30414
1765
15482
1.18
8.15
2.9
2.7
0.3
0.3
e6/l
0.15
1283
11278
3352
30881
1.14
7.95
6.2
5.7
0.7
0.7
%
0.26
3137
28947
3820
35523
1.14
7.85
6.2
5.8
0.2
0.2
e9/l
0.10
3463
32067
1074
9048
1.22
7.73
2.4
2.3
1.0
1.2
e6/l
0.69
572
4845
3812
35467
1.14
7.72
5.9
5.6
2.0
2.0
e9/l
0.27
3453
32154
4168
39024
1.14
7.63
8.4
8.3
4.0
3.9
e9/l
0.72
3702
34551
3567
33111
1.14
7.35
5.8
5.5
56.5
56.5
%
0.01
3360
31294
3325
30737
1.14
7.28
5.4
5.2
9.2
9.5
umol/l
1.35
3114
28965
1777
15723
1.17
7.26
3.3
3.3
—
—
—
0
0
1346
11662
1.18
7.11
1.7
1.6
—
—
—
0
0
729
5963
1.24
6.96
2.2
2.7
48.6
37.4
u/ml
0.26
705
5765
5290
50449
1.14
6.93
2.9
2.7
34.6
33.3
u/l
0.70
5061
48371
3601
33537
1.13
6.88
6.1
5.6
29.7
29.8
%
0.22
3386
31599
2905
26693
1.14
6.87
5.8
5.3
1.2
1.2
mmol/l
1.07
2471
22647
277
1988
1.41
6.76
3.4
2.4
—
—
—
0
0
2602
23763
1.14
6.73
5.1
4.7
1.2
1.2
mmol/l
0.84
2365
21778
530
4200
1.28
6.63
2.8
1.9
—
—
—
0
0
1756
15621
1.16
6.61
2.8
2.6
—
—
—
0
0
1905
17056
1.15
6.56
2.9
2.7
39.2
72.8
e6/l
1.43
1405
12649
996
8464
1.20
6.52
2.6
2.4
4.8
5.0
e6/l
0.13
495
4280
570
4580
1.26
6.37
2.7
1.8
—
—
—
0
0
2119
19146
1.14
6.37
2.5
2.4
—
—
—
0
0
2042
18430
1.14
6.21
3.7
3.5
0.0
0.0
estimate
0.02
792
6993
572
4620
1.26
6.12
2.8
1.8
—
—
—
0
0
1635
14545
1.15
6.10
1.3
1.3
11.4
9.1
u/ml
0.72
639
6304
569
4604
1.25
6.00
2.3
1.8
—
—
—
0
0
448
3526
1.29
5.94
3.0
1.9
—
—
—
0
0
1677
14972
1.15
5.94
3.6
3.3
98.1
98.8
%
0.59
1623
14488
2591
23814
1.13
5.88
4.5
4.2
36.8
36.8
g/l
0.10
2440
22264
7633
75077
1.24
5.67
10.2
9.6
—
—
—
0
0
71
387
1.84
5.59
1.2
1.1
—
—
—
0
0
6936
67677
1.16
5.50
5.1
5.1
1.7
2.0
mu/l
3.48
6557
64526
3237
30243
1.12
5.42
8.3
7.9
0.0
0.0
e9/l
3.16
2677
24870
2414
22196
1.12
5.34
1.7
1.8
99.3
99.8
pmol/l
0.18
1329
11884
555
4559
1.23
5.14
2.5
1.8
—
—
—
0
0
8022
79502
1.40
4.89
16.5
15.3
269.8
269.5
e9/l
0.12
7886
78148
8027
79562
1.41
4.87
16.4
15.2
30.2
30.0
pg
31.78
7958
78927
8027
79565
1.40
4.83
16.4
15.3
90.7
90.1
fl
29.35
7956
78933
8027
79574
1.40
4.74
16.4
15.3
4.4
4.5
e12/l
13.47
7883
78138
8028
79591
1.40
4.68
16.5
15.4
6.8
6.7
e9/l
4.96
7885
78108
8028
79606
1.39
4.52
16.5
15.4
133.0
133.0
g/l
0.01
7960
78964
1667
15133
1.13
4.46
1.3
1.3
45.1
29.1
iu/ml
0.39
518
4725
2085
19177
1.12
4.45
2.4
2.4
53.1
56.5
u/l
3.78
1927
17854
6221
60510
1.12
4.31
4.4
4.4
14.3
14.3
pmol/l
0.18
5840
57175
1213
10814
1.14
4.31
2.7
2.4
519.5
522.3
mosm/kgh2o
0.16
1027
9155
3628
34379
1.10
4.27
4.0
3.8
6.2
6.3
mmol/l
0.87
3261
30878
228
1719
1.34
4.24
2.2
1.9
1.4
1.4
g/l
0.46
198
1493
1000
8807
1.15
4.23
1.3
1.3
24.9
25.9
iu/l
0.51
874
7734
505
4200
1.22
4.20
1.4
1.3
—
—
—
0
0
1666
15181
1.12
4.16
1.9
2.0
178.5
137.9
u/l
0.72
1585
14415
1988
18321
1.11
4.05
4.8
5.1
1.1
1.1
inr
0.08
660
6195
384
3120
1.24
4.00
1.6
1.7
—
—
—
0
0
1297
11701
1.13
3.82
1.4
1.4
549.6
566.2
titre
0.11
269
2384
74
463
1.60
3.69
1.6
1.6
1.5
1.2
promille
1.13
55
348
1857
17126
1.11
3.69
1.7
1.7
—
—
—
0
0
1801
16587
1.11
3.67
6.2
6.3
—
—
—
0
0
1983
18357
1.11
3.66
2.5
2.5
29.9
69.2
ng/l
0.46
794
7593
569
4855
1.18
3.62
1.3
1.2
—
—
—
0
0
4333
41592
1.09
3.58
2.7
2.7
—
—
—
0
0
2117
19686
1.10
3.56
3.0
3.1
2.3
2.3
mmol/l
0.22
1913
17775
1620
14864
1.11
3.54
3.5
3.4
1.0
1.0
kg/l
0.28
232
2269
70
438
1.60
3.51
4.9
2.1
—
—
—
0
0
1309
11885
1.12
3.45
2.4
2.3
9.2
8.6
e6/l
0.42
1124
10272
2247
20983
1.10
3.44
1.7
1.7
—
—
—
0
0
88
584
1.51
3.43
1.7
1.4
55.8
67.0
mmol/l
1.69
75
457
14
47
2.98
3.40
9.1
11.1
4.6
5.0
mmol/l
0.28
14
47
7
10
7.00
3.36
1.0
1.0
—
—
—
0
0
1730
16007
1.10
3.19
4.0
3.5
7.4
7.4
ph
0.29
331
3050
580
5024
1.17
3.11
7.3
6.2
104.7
104.9
mmol/l
0.41
570
4930
565
4894
1.17
3.04
3.0
3.3
—
—
—
0
0
6532
64038
1.10
2.94
3.4
3.5
5.6
5.6
mmol/l
0.94
6127
60424
495
4261
1.17
2.89
7.1
6.5
13.3
13.8
kpa
1.25
469
4069
495
4262
1.17
2.88
7.1
6.5
5.1
5.0
kpa
0.24
471
4074
873
7832
1.13
2.84
1.8
1.8
—
—
—
0
0
1037
9412
1.12
2.76
2.4
2.4
2.4
2.4
mmol/l
0.04
905
8190
978
8853
1.12
2.73
2.7
2.8
253.2
281.7
ng/l
0.17
489
4503
1224
11216
1.11
2.73
2.5
2.4
107.1
97.8
ug/g
0.47
928
8804
2444
23108
1.08
2.71
3.3
3.0
29.6
29.5
u/l
0.01
2318
22152
789
7061
1.13
2.68
3.1
2.4
5.7
6.0
umol/l
0.21
641
5905
1289
11859
1.10
2.65
3.9
3.6
—
—
—
0
0
847
7624
1.12
2.62
1.6
1.6
—
—
—
0
0
427
3665
1.17
2.62
7.4
7.0
96.2
96.4
%
0.20
410
3507
410
3508
1.18
2.61
7.9
7.2
120.0
120.9
g/l
0.44
398
3372
35
199
1.76
2.59
2.9
2.8
—
—
—
0
0
222
1792
1.25
2.58
1.5
1.6
—
—
—
0
0
233
1892
1.24
2.57
10.2
8.3
24.2
24.2
mmol/l
0.01
217
1783
382
3254
1.18
2.57
9.6
7.5
—
—
—
0
0
81
565
1.44
2.56
2.2
2.0
46.3
45.7
%
0.06
13
92
836
7535
1.12
2.53
1.5
1.5
—
—
—
0
0
318
2672
1.20
2.51
1.4
1.4
20.9
24.7
u/l
1.42
240
2226
148
1143
1.30
2.48
1.3
1.5
—
—
—
0
0
6311
61906
1.08
2.48
13.1
12.3
13.4
13.5
%
1.12
6199
60775
776
6980
1.12
2.44
1.4
1.3
—
—
—
0
0
491
4286
1.15
2.44
7.0
6.5
0.8
0.8
mmol/l
0.05
369
3241
2588
24607
1.08
2.44
1.7
1.7
—
—
—
0
0
272
2261
1.21
2.41
9.4
8.1
93.7
94.4
%
0.72
272
2250
94
682
1.38
2.40
3.2
2.5
1.3
1.4
%
0.14
66
541
593
5258
1.14
2.36
2.5
2.3
4.3
4.1
e9/l
1.11
483
4471
2116
19991
1.08
2.36
1.3
1.3
1.7
1.5
u/ml
0.37
626
5996
244
2014
1.22
2.34
8.6
8.3
—
—
—
0
0
115
866
1.33
2.33
1.0
1.1
—
—
—
0
0
918
8368
1.11
2.28
1.7
1.7
1159.8
1196.0
nmol/l
0.63
732
6629
60
406
1.48
2.25
3.5
2.4
57.2
56.3
%
0.10
38
260
1269
11761
1.09
2.25
1.4
1.4
21.3
21.2
nmol/l
0.09
1114
10483
335
2860
1.18
2.24
1.4
1.5
84.1
99.2
pmol/l
0.40
330
2793
892
8138
1.11
2.19
3.2
3.0
0.8
0.8
mmol/l
0.72
838
7640
1772
16680
1.08
2.16
1.4
1.4
2.1
2.1
g/l
0.60
1088
10764
46
297
1.55
2.15
1.9
1.9
—
—
—
0
0
9
30
3.00
2.14
1.2
1.3
—
—
—
0
0
46
298
1.55
2.12
2.2
2.4
126.5
174.6
umol/l
0.72
31
148
31
511
0.61
2.11
1.2
1.5
—
—
—
0
0
888
8119
1.11
2.10
2.4
2.2
2.4
2.5
g/l
2.13
801
7545
568
5070
1.13
2.07
2.5
2.5
10.5
10.5
g/l
0.18
520
4658
171
1380
1.24
2.07
2.9
3.3
165.8
267.6
u/ml
0.34
146
1179
40
253
1.58
2.05
2.1
2.0
—
—
—
0
0
461
4064
1.14
2.04
1.4
1.4
—
—
—
0
0
139
1098
1.27
2.02
1.8
1.9
38.6
39.0
g/l
0.36
122
979
272
2305
1.19
2.02
3.4
4.6
—
—
—
0
0
165
1331
1.24
2.01
3.6
3.0
1.4
1.3
mg/l
0.37
158
1255
72
518
1.39
1.99
2.2
2.3
—
—
—
0
0
64
452
1.42
1.97
2.8
2.7
814.3
910.3
e6/l
0.46
28
198
36
225
1.60
1.95
22.9
25.7
110.4
113.1
ug/l
0.10
30
186
764
6964
1.11
1.93
1.2
1.2
—
—
—
0
0
701
6370
1.11
1.89
3.8
3.3
—
—
—
0
0
172
1407
1.23
1.87
1.9
2.0
3.7
3.7
g/l
0.20
130
1025
219
1836
1.20
1.86
2.5
2.1
10.5
10.2
mg/l
0.31
210
1733
486
4330
1.13
1.85
3.4
3.3
—
—
—
0
0
49
333
1.47
1.85
3.2
3.0
9.6
7.8
mg/l
0.57
39
250
10
40
2.50
1.83
1.0
1.6
—
—
—
0
0
794
7279
1.10
1.81
2.0
2.1
29.2
29.1
s
0.24
770
7036
298
2575
1.16
1.78
2.6
2.0
0.2
0.2
g/l
0.61
279
2456
309
2679
1.16
1.77
1.8
1.9
7.1
5.2
ug/l
0.34
271
2337
496
4441
1.12
1.76
3.2
3.6
6.1
22.5
ug/l
1.17
366
3177
520
4670
1.12
1.75
4.1
3.8
0.9
0.6
%
0.38
106
813
45
305
1.48
1.74
1.1
1.1
2.1
2.5
u/ml
0.09
27
163
5866
57635
1.06
1.73
4.0
4.1
36.8
37.4
mmol/mol
5.77
5525
54736
437
3889
1.13
1.72
1.6
1.8
1.3
1.3
g/l
0.21
403
3611
306
2660
1.16
1.70
2.6
1.9
1.1
1.2
g/l
0.97
289
2545
0
48
0.00
1.69
0.0
1.6
—
32.6
—
0
37
520
4683
1.12
1.68
2.3
2.2
0.2
0.2
g/l
2.17
484
4438
26
157
1.66
1.65
4.6
4.8
—
—
—
0
0
2151
20569
1.06
1.63
3.0
2.8
—
—
—
0
0
5
14
3.57
1.61
1.0
1.3
—
—
—
0
0
1705
16192
1.07
1.61
2.1
2.1
2.7
2.7
mg/l
0.18
1460
14026
112
892
1.26
1.59
2.7
3.2
34.6
41.2
mg/l
0.45
93
718
156
1290
1.21
1.58
2.0
2.0
10.5
10.2
g/l
0.31
134
1115
6921
68427
1.07
1.56
11.8
10.9
39.6
39.5
%
0.22
5723
56604
34
223
1.53
1.56
1.1
1.4
—
—
—
0
0
974
9078
1.08
1.55
2.4
2.2
14.9
14.5
umol/l
0.98
890
8444
53
381
1.39
1.54
3.0
2.5
0.1
0.3
e9/l
1.34
53
376
337
2975
1.14
1.53
1.3
1.2
—
—
—
0
0
1446
13681
1.07
1.53
2.7
2.7
—
—
—
0
0
28
432
0.65
1.52
1.1
1.3
—
—
—
0
0
0
43
0.00
1.52
0.0
1.7
—
10.9
—
0
37
264
2295
1.16
1.50
1.5
1.6
8.6
10.0
u/ml
—
5
63
111
893
1.25
1.47
2.7
3.2
27.4
38.6
mg/l
0.81
92
720
781
7233
1.09
1.46
2.6
2.3
24.5
23.9
%
0.65
669
6278
555
5062
1.10
1.45
4.3
4.0
0.7
0.9
%
0.37
140
1085
99
788
1.26
1.44
3.7
2.9
31.6
33.1
umol/l
0.38
90
684
143
1186
1.21
1.43
3.2
2.8
7.4
7.4
ph
0.36
112
989
241
2769
0.87
1.42
1.1
1.2
—
—
—
0
0
339
3015
1.13
1.40
2.3
2.5
71.3
72.0
e9/l
0.11
255
2188
277
2433
1.14
1.39
1.9
2.0
—
—
—
0
0
172
1457
1.18
1.38
1.3
1.3
—
—
—
0
0
117
955
1.23
1.38
2.9
2.8
24.9
24.2
mmol/l
1.17
100
842
533
4869
1.10
1.36
4.4
4.1
0.1
0.2
%
1.31
134
1013
5
17
2.94
1.36
1.0
1.2
160.0
219.2
nmol/l
—
5
17
1050
11158
0.93
1.35
1.3
1.3
—
—
—
0
0
258
2261
1.15
1.35
1.4
1.3
15.0
7.0
u/ml
0.72
39
234
470
4274
1.11
1.32
2.7
2.6
—
—
—
0
0
218
1890
1.16
1.32
6.1
4.1
24.2
24.3
mmol/l
0.09
194
1685
562
5158
1.10
1.31
1.2
1.3
25.5
36.7
au/ml
1.40
15
212
261
2295
1.14
1.31
1.3
1.3
7.0
8.4
u/ml
0.30
52
380
9
43
2.09
1.30
1.0
1.6
—
—
—
0
0
104
845
1.23
1.30
3.2
2.4
8.9
8.8
kpa
0.20
94
790
6838
67672
1.06
1.29
3.6
3.7
2.9
2.9
mmol/l
0.63
6480
64234
101
821
1.23
1.26
5.4
3.7
—
—
—
0
0
105
858
1.23
1.25
2.8
3.1
1.5
1.3
ratio
—
6
100
1700
16270
1.06
1.25
1.7
1.7
1.0
0.8
mg/l
0.99
1256
12116
605
5586
1.09
1.25
2.3
2.3
17.9
22.3
au/ml
0.70
39
458
385
3478
1.11
1.25
4.5
3.6
5.9
5.8
kpa
0.27
377
3364
787
7347
1.08
1.24
1.4
1.4
—
—
—
0
0
506
4636
1.10
1.24
11.6
12.2
1.1
1.1
inr
0.19
88
791
389
3520
1.11
1.23
8.1
6.1
1.2
1.2
mmol/l
0.00
374
3403
11
56
1.97
1.22
14.5
4.2
—
—
—
0
0
4101
40117
1.04
1.21
2.9
3.0
72.9
67.0
ug/l
1.54
3872
38261
44
322
1.37
1.20
2.3
2.8
42.1
46.3
%
—
10
115
381
3449
1.11
1.20
4.5
3.6
1.9
1.8
mmol/l
0.27
308
2791
288
2567
1.13
1.19
3.0
2.7
—
—
—
0
0
285
2539
1.13
1.19
1.3
1.3
36.6
35.5
u/ml
0.04
22
183
173
1491
1.16
1.17
1.9
1.9
—
—
—
0
0
198
1725
1.15
1.16
1.2
1.2
—
—
—
0
0
364
3294
1.11
1.16
9.6
7.0
7.8
7.1
mmol/l
1.22
345
3175
0
34
0.00
1.16
0.0
1.5
—
1.0
—
0
28
28
190
1.48
1.15
3.8
4.7
6259.2
2794.0
mg/l
0.23
21
136
103
849
1.22
1.15
5.4
5.6
376.4
374.5
umol/l
0.04
97
724
103
849
1.22
1.15
1.5
1.6
—
—
—
0
0
510
4695
1.09
1.15
4.3
4.1
0.1
0.2
%
0.21
108
873
44
326
1.35
1.13
2.3
2.4
10.6
10.8
%
0.17
44
326
101
833
1.22
1.13
1.1
1.1
1.5
1.5
g/l
0.02
94
762
3034
29522
1.04
1.13
2.3
2.3
75.4
3032.1
nmol/l
0.50
2817
27729
34
242
1.41
1.11
1.4
1.7
191.3
145.5
au/ml
—
5
31
28
192
1.46
1.11
1.9
1.6
—
—
—
0
0
64
503
1.27
1.10
3.0
2.7
—
—
—
0
0
620
5768
1.08
1.10
2.5
2.3
34.0
35.4
u/l
0.20
520
4928
406
3710
1.10
1.09
1.3
1.3
1.4
1.0
u/ml
0.21
30
307
8
41
1.95
1.08
5.3
3.4
—
—
—
0
0
685
7323
0.93
1.08
1.6
1.7
—
—
—
0
0
7
32
2.19
1.08
1.6
1.3
320.3
535.4
nmol/l
—
7
32
242
2718
0.89
1.08
1.2
1.2
—
—
—
0
0
107
893
1.20
1.07
4.3
6.5
11.1
11.1
mmol/l
0.10
96
797
83
675
1.23
1.07
1.1
1.1
—
—
—
0
0
121
1022
1.19
1.07
2.5
2.0
131.7
130.6
g/l
0.22
90
765
308
2778
1.11
1.07
3.8
3.1
4.6
4.7
kpa
0.12
301
2676
299
2693
1.11
1.06
2.3
2.5
138.0
107.8
ng/l
0.63
264
2398
107
894
1.20
1.06
4.3
6.5
106.4
105.6
mmol/l
1.31
96
798
135
1573
0.86
1.03
1.1
1.1
12.4
10.6
au/ml
0.12
11
119
5
22
2.27
1.03
3.4
2.2
—
—
—
0
0
233
2080
1.12
0.99
1.3
1.3
—
—
—
0
0
7
133
0.53
0.98
1.3
1.1
—
—
—
0
0
12
69
1.74
0.96
1.7
1.8
—
—
—
0
0
114
970
1.18
0.95
2.1
1.7
32.2
35.5
iu/ml
—
10
55
28
199
1.41
0.95
1.0
1.1
—
—
—
0
0
183
1614
1.14
0.95
1.3
1.4
332.6
313.5
ug/g
0.50
101
825
0
32
0.00
0.95
0.0
1.0
—
0.1
—
0
23
75
614
1.22
0.94
1.2
1.2
—
—
—
0
0
503
4677
1.08
0.94
1.4
1.3
200.9
237.1
miu/ml
1.84
249
2414
28
200
1.40
0.93
2.8
2.7
117.3
100.6
ng/l
0.09
13
102
105
890
1.18
0.92
2.9
2.1
17.0
16.8
%
0.26
54
430
480
4459
1.08
0.92
2.3
2.5
1.7
1.7
%
0.26
428
3991
458
4250
1.08
0.90
3.4
3.1
1.2
1.2
mmol/l
1.01
399
3728
56
446
1.26
0.90
4.1
2.8
—
—
—
0
0
630
5918
1.07
0.90
6.5
4.9
1.0
1.0
mmol/l
0.46
595
5561
6
29
2.07
0.89
1.2
1.1
—
—
—
0
0
103
1208
0.85
0.89
1.4
1.5
0.5
0.6
g/l
0.93
72
918
114
1326
0.86
0.89
1.1
1.1
115.0
119.4
%
0.76
104
1218
8
42
1.91
0.88
1.4
1.6
322.3
306.2
umol/24h
—
8
42
5
105
0.48
0.88
1.4
1.1
—
—
—
0
0
12
193
0.62
0.87
1.0
1.2
—
1.9
—
0
38
6733
66785
1.05
0.84
3.4
3.4
1.6
1.6
mmol/l
0.08
6420
63722
737
6977
1.06
0.84
1.3
1.4
—
—
—
0
0
8
45
1.78
0.84
1.0
1.6
—
—
—
0
0
257
2334
1.10
0.83
5.3
6.4
24.2
24.3
mmol/l
0.16
242
2163
116
1002
1.16
0.83
3.4
2.8
2.0
2.2
mmol/l
0.28
63
618
1827
17698
1.04
0.83
4.1
3.9
—
—
—
0
0
6765
67116
1.05
0.83
3.4
3.5
4.9
4.9
mmol/l
0.31
6459
64138
166
1472
1.13
0.82
3.2
4.3
—
—
—
0
0
11
65
1.69
0.82
1.0
1.1
1.5
1.5
umol/24h
0.04
11
65
181
1616
1.12
0.81
1.3
1.3
—
—
—
0
0
162
1437
1.13
0.80
3.9
5.0
1.2
1.2
mmol/l
0.21
146
1257
193
1732
1.12
0.79
3.8
3.2
1.6
1.3
%
1.77
193
1722
20
139
1.44
0.79
3.4
2.1
—
—
—
0
0
6475
64200
1.04
0.78
3.1
3.1
1.2
1.2
mmol/l
0.69
6147
61156
75
890
0.84
0.77
2.7
2.6
53.6
79.9
ug/min
0.48
49
569
40
313
1.28
0.77
1.7
1.9
8.6
9.6
mg/l
0.56
31
256
2829
28914
0.97
0.76
2.2
2.2
—
—
—
0
0
30
227
1.32
0.74
1.2
1.3
—
—
—
0
0
80
679
1.18
0.74
6.3
3.7
60.2
62.4
%
0.41
80
679
188
1694
1.11
0.74
3.8
3.1
0.6
0.7
%
1.72
176
1625
37
289
1.28
0.73
2.6
3.1
0.8
0.8
nmol/l
0.07
24
217
5
25
2.00
0.72
1.2
1.1
—
—
—
0
0
15
100
1.50
0.72
1.1
1.2
—
—
—
0
0
340
3154
1.08
0.72
1.2
1.2
10.5
11.9
u/l
1.29
283
2643
32
246
1.30
0.71
1.2
1.2
6.0
6.1
mmol/l
0.09
27
226
233
2128
1.10
0.71
1.1
1.1
—
—
—
0
0
154
1721
0.89
0.71
1.6
1.6
7.7
7.6
mmol/l
0.29
100
1064
19
134
1.42
0.71
1.1
1.1
—
—
—
0
0
9
57
1.58
0.71
1.1
1.0
—
—
—
0
0
31
400
0.77
0.71
1.1
1.1
—
—
—
0
0
170
1528
1.11
0.71
4.3
4.8
0.9
0.9
%
1.08
160
1423
89
1031
0.86
0.70
1.4
1.5
10.4
11.0
mmol/l
0.30
12
124
248
2274
1.09
0.70
1.2
1.2
—
—
—
0
0
171
1539
1.11
0.70
4.3
4.7
1.9
1.7
%
0.84
160
1432
1531
14839
1.04
0.69
3.5
3.1
7.4
7.5
mmol/l
0.17
1323
12854
199
1808
1.10
0.68
1.1
1.1
—
—
—
0
0
338
3144
1.08
0.68
2.3
2.3
67.0
67.3
g/l
0.28
310
2907
24
319
0.75
0.68
1.5
1.7
—
—
—
0
0
11
69
1.60
0.68
1.0
1.1
0.1
0.6
u/ml
—
5
27
127
1430
0.89
0.67
1.3
1.2
2.9
4.1
u/ml
1.09
60
575
1148
11902
0.96
0.67
2.0
2.1
—
—
—
0
0
15
102
1.47
0.67
1.0
1.3
—
—
—
0
0
7
43
1.63
0.66
1.0
1.1
—
—
—
0
0
14
94
1.49
0.66
1.0
1.4
—
161.3
—
0
14
79
678
1.17
0.66
3.3
2.4
—
—
—
0
0
167
1509
1.11
0.65
1.4
1.3
147.5
107.8
u/ml
0.72
36
365
50
413
1.21
0.64
1.3
1.5
31232.4
33755.4
e6/l
0.03
32
285
144
1292
1.12
0.64
2.5
2.6
—
—
—
0
0
44
536
0.82
0.63
17.1
16.8
1510.3
4627.0
nmol/l
0.79
44
514
198
1808
1.10
0.63
1.1
1.1
—
—
—
0
0
130
1161
1.12
0.63
1.3
1.4
—
—
—
0
0
25
190
1.32
0.62
1.0
1.0
—
—
—
0
0
25
190
1.32
0.62
1.0
1.0
—
—
—
0
0
25
190
1.32
0.62
1.0
1.0
—
—
—
0
0
125
1398
0.89
0.61
1.2
1.2
—
—
—
0
0
6
105
0.57
0.61
1.0
1.4
—
—
—
0
0
59
498
1.19
0.61
1.6
1.8
280.6
282.6
mosm/kgh2o
0.29
45
406
13
88
1.48
0.60
1.8
2.0
—
—
—
0
0
122
1089
1.12
0.60
1.6
1.7
6455.5
8456.5
e6/l
0.70
91
820
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
177
1613
1.10
0.60
1.3
1.3
19.3
20.8
u/ml
—
5
36
23
300
0.77
0.59
1.3
1.2
—
—
—
0
0
268
2489
1.08
0.59
2.4
2.1
47.8
4.4
iu/l
0.51
126
1066
39
317
1.23
0.59
2.4
2.4
—
—
—
0
0
42
509
0.82
0.59
1.0
1.1
1441.2
1505.7
miu/ml
0.14
42
509
83
949
0.87
0.58
3.8
4.3
111.5
93.7
u/ml
0.09
34
313
43
355
1.21
0.57
2.6
2.3
—
—
—
0
0
248
2671
0.93
0.57
2.3
2.2
—
—
—
0
0
66
567
1.17
0.57
1.1
1.1
—
—
—
0
0
58
493
1.18
0.57
1.7
1.4
—
—
—
0
0
171
1561
1.10
0.57
1.3
1.2
280.6
269.0
u/ml
0.23
121
1053
21
158
1.33
0.57
1.7
1.7
—
—
—
0
0
71
818
0.87
0.56
1.4
1.4
0.4
0.4
g/l
0.30
47
577
11
73
1.51
0.56
2.7
2.2
—
—
—
0
0
8
55
1.45
0.56
2.9
2.1
—
—
—
0
0
112
1001
1.12
0.55
3.2
3.3
—
—
—
0
0
71
817
0.87
0.55
1.4
1.4
2.8
3.0
g/l
0.45
46
573
71
817
0.87
0.55
1.4
1.4
6.9
6.6
g/l
0.22
46
575
43
516
0.83
0.55
13.5
11.9
861.0
836.7
nmol/l
0.15
43
496
555
5292
1.05
0.55
1.2
1.2
—
—
—
0
0
569
5431
1.05
0.55
1.5
1.6
285.2
314.1
mu/l
1.06
508
4825
6362
64047
0.97
0.55
13.8
12.8
332.2
331.8
g/l
2.97
6318
63602
909
8772
1.04
0.54
1.2
1.2
—
—
—
0
0
182
1674
1.09
0.53
2.8
2.5
—
—
—
0
0
6
39
1.54
0.53
1.2
1.2
—
—
—
0
0
1496
14576
1.03
0.53
2.2
2.0
1942.4
2497.9
umol/l
0.41
1344
13068
13
91
1.43
0.52
1.0
1.0
0.1
0.2
u/ml
—
5
36
65
563
1.16
0.52
1.1
1.2
—
—
—
0
0
29
359
0.81
0.51
1.3
1.5
124.6
130.6
nmol/l
0.34
29
359
497
5211
0.95
0.51
1.4
1.5
—
—
—
0
0
110
1221
0.90
0.50
3.8
3.3
28.8
21.3
mg/l
0.71
54
730
79
697
1.13
0.50
1.3
1.2
—
—
—
0
0
497
5206
0.95
0.50
1.4
1.4
—
—
—
0
0
61
529
1.15
0.49
4.0
4.3
6.0
7.2
mmol/l
2.36
52
435
10
144
0.69
0.49
1.3
1.6
—
—
—
0
0
844
8156
1.04
0.48
1.2
1.2
175.9
151.9
iu/ml
0.71
335
3273
206
1915
1.08
0.48
1.3
1.3
122.6
155.3
titre
0.18
19
185
38
317
1.20
0.48
3.5
3.1
—
—
—
0
0
30
244
1.23
0.48
1.0
1.1
—
—
—
0
0
28
344
0.81
0.47
2.7
3.0
—
—
—
0
0
1290
12567
1.03
0.47
1.4
1.4
—
—
—
0
0
75
663
1.13
0.47
1.6
2.0
3.5
222.3
u/ml
0.53
66
565
46
538
0.85
0.47
5.8
6.6
—
—
—
0
0
10
68
1.47
0.47
1.1
2.1
0.5
0.9
u/field
—
10
68
12
85
1.41
0.46
1.2
1.2
—
—
—
0
0
7
48
1.46
0.46
1.9
3.9
—
—
—
0
0
512
5347
0.95
0.46
1.5
1.5
—
—
—
0
0
15
111
1.35
0.46
1.5
1.4
—
—
—
0
0
152
1398
1.09
0.46
1.0
1.1
0.2
0.3
u/ml
0.09
21
288
657
6325
1.04
0.46
1.4
1.4
—
—
—
0
0
47
402
1.17
0.46
1.4
1.3
—
—
—
0
0
91
816
1.12
0.46
1.2
1.4
—
—
—
0
0
117
1283
0.91
0.44
2.4
1.9
4.8
1.7
ug/l
0.89
99
1130
435
4155
1.05
0.44
1.1
1.1
—
—
—
0
0
1170
12008
0.97
0.44
3.3
3.3
399.9
504.1
mg/l
0.32
729
7282
82
734
1.12
0.43
1.0
1.1
0.3
1.4
u/ml
1.03
18
194
75
668
1.12
0.43
1.0
1.0
—
—
—
0
0
14
104
1.35
0.43
1.1
1.2
—
—
—
0
0
17
218
0.78
0.42
1.4
1.5
—
—
—
0
0
658
6352
1.04
0.42
3.4
3.4
4.6
4.5
pmol/l
0.52
590
5751
257
2424
1.06
0.42
3.2
2.7
5.2
5.1
kpa
1.92
236
2272
309
3256
0.95
0.41
1.7
1.7
—
—
—
0
0
59
669
0.88
0.41
1.1
1.2
0.1
0.9
u/ml
1.60
21
250
215
2290
0.94
0.41
1.2
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
76
680
1.12
0.41
2.7
3.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
0.2
—
0
9
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
35
296
1.18
0.40
1.0
1.1
—
—
—
0
0
21
260
0.81
0.40
1.5
2.3
323.6
178.0
e6/l
0.42
11
142
0
18
0.00
0.40
0.0
2.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
2.0
—
—
—
0
0
0
18
0.00
0.40
0.0
2.0
—
—
—
0
0
96
873
1.10
0.39
1.6
1.4
—
—
—
0
0
7
103
0.68
0.39
1.1
1.0
—
—
—
0
0
25
205
1.22
0.39
1.2
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
187
1751
1.07
0.39
3.4
2.8
0.2
0.3
g/l
4.71
67
694
63
560
1.13
0.38
1.9
2.1
10.8
13.0
%
0.80
21
303
18
142
1.27
0.38
1.1
1.4
—
—
—
0
0
42
363
1.16
0.38
1.5
1.5
1713.6
2249.1
ml
—
5
61
20
246
0.81
0.36
1.0
1.1
5.1
5.0
mg/g
0.01
20
231
131
1214
1.08
0.36
3.1
2.3
—
—
—
0
0
52
587
0.89
0.36
1.3
1.4
—
—
—
0
0
52
587
0.89
0.36
1.3
1.4
—
—
—
0
0
52
587
0.89
0.36
1.3
1.4
—
—
—
0
0
52
587
0.89
0.36
1.3
1.4
—
—
—
0
0
74
818
0.90
0.36
1.4
1.5
—
—
—
0
0
6
43
1.40
0.35
1.7
1.3
—
—
—
0
0
6
43
1.40
0.35
1.0
1.2
—
—
—
0
0
139
1295
1.07
0.35
1.1
1.1
—
—
—
0
0
24
287
0.84
0.34
1.2
1.1
—
—
—
0
0
21
172
1.22
0.34
1.0
1.0
—
—
—
0
0
76
690
1.10
0.34
2.6
2.4
1.5
1.3
e9/l
0.30
42
408
622
6031
1.03
0.34
1.2
1.3
250.0
183.1
u/ml
0.56
576
5592
19
154
1.23
0.33
2.1
2.1
—
—
—
0
0
754
7749
0.97
0.33
1.5
1.4
—
—
—
0
0
486
4693
1.04
0.33
1.1
1.1
72.8
229.0
titre
3.16
13
121
136
1456
0.93
0.33
1.3
1.2
—
—
—
0
0
16
199
0.80
0.33
1.1
1.0
0.1
1.0
u/ml
—
9
133
79
721
1.10
0.32
1.4
1.5
—
—
—
0
0
124
1155
1.07
0.32
1.4
1.3
34.0
57.7
u/ml
—
8
74
209
1982
1.06
0.32
1.1
1.1
1.6
1.7
u/ml
0.05
44
489
103
953
1.08
0.32
2.0
2.0
—
—
—
0
0
19
230
0.83
0.31
1.1
1.2
—
—
—
0
0
48
538
0.89
0.31
1.1
1.1
—
—
—
0
0
159
1498
1.06
0.30
1.2
1.2
—
—
—
0
0
377
3633
1.04
0.30
3.8
3.3
80.4
75.0
ng/l
0.49
347
3250
16
129
1.24
0.30
1.9
1.7
—
—
—
0
0
151
1603
0.94
0.30
1.0
1.1
2.5
2.7
u/ml
0.11
88
891
24
203
1.18
0.29
1.1
1.1
—
—
—
0
0
59
534
1.11
0.29
1.5
1.6
—
—
—
0
0
32
278
1.15
0.29
1.6
1.9
—
—
—
0
0
29
250
1.16
0.29
1.2
1.4
14180.8
3013.7
e6/l
0.47
24
173
268
2798
0.96
0.29
1.1
1.1
3.7
4.5
u/ml
0.28
55
454
49
439
1.12
0.29
2.1
2.3
—
—
—
0
0
104
968
1.08
0.29
1.5
1.4
—
—
—
0
0
151
1600
0.94
0.28
1.5
1.5
7.1
6.6
mmol/l
0.69
114
1149
279
2676
1.04
0.28
2.4
2.4
0.2
0.2
e6/l
0.10
267
2546
64
584
1.10
0.28
1.8
1.7
47.7
49.6
%
0.15
40
359
250
2394
1.05
0.28
3.3
2.7
7.4
7.4
ph
0.09
43
321
9
118
0.76
0.27
3.8
5.0
—
—
—
0
0
49
442
1.11
0.27
1.7
1.6
39.2
40.7
%
0.09
29
259
14
113
1.24
0.26
1.1
1.2
—
—
—
0
0
105
982
1.07
0.26
4.0
2.7
—
—
—
0
0
13
104
1.25
0.26
2.3
2.1
—
—
—
0
0
24
277
0.87
0.25
2.7
2.2
1.6
1.2
ug/l
0.33
24
264
9
76
1.18
0.24
2.4
2.5
—
—
—
0
0
9
77
1.17
0.24
1.6
1.1
—
—
—
0
0
60
551
1.09
0.24
1.2
1.2
15.1
21.2
u/l
0.85
54
479
66
609
1.08
0.24
1.1
1.2
—
—
—
0
0
6
82
0.73
0.24
2.8
2.3
—
—
—
0
0
69
638
1.08
0.24
1.1
1.1
1.0
1.1
ratio
0.03
20
246
6
83
0.72
0.24
2.8
2.1
1.2
1.2
mmol/l
—
6
77
24
208
1.15
0.24
1.3
1.5
—
—
—
0
0
107
1136
0.94
0.23
1.1
1.1
137.8
9114.3
iu/ml
0.63
27
295
5
39
1.28
0.23
1.0
1.0
—
—
—
0
0
63
582
1.08
0.23
1.1
1.2
—
—
—
0
0
33
369
0.89
0.22
2.0
2.1
—
—
—
0
0
5
40
1.25
0.22
1.0
1.2
286.8
153.2
ug/g
—
5
30
15
125
1.20
0.22
1.7
1.1
—
—
—
0
0
204
2124
0.96
0.22
8.0
7.0
—
—
—
0
0
65
603
1.08
0.21
2.8
3.1
—
—
—
0
0
1600
15804
1.02
0.21
1.6
1.6
1.4
1.3
mmol/l
0.36
1382
13815
5
42
1.19
0.21
1.0
1.2
—
—
—
0
0
214
2060
1.04
0.21
1.3
1.3
46.4
38.0
u/ml
0.35
30
210
43
392
1.10
0.21
3.1
2.5
123.6
93.2
nmol/l
0.25
43
385
78
731
1.07
0.20
3.4
3.5
198.1
555.7
u/ml
0.48
72
676
328
3187
1.03
0.20
1.7
1.7
—
—
—
0
0
122
1161
1.05
0.20
1.1
1.1
—
—
—
0
0
16
136
1.18
0.20
1.1
1.7
—
—
—
0
0
132
1259
1.05
0.20
2.3
2.1
410.3
328.3
ug/l
0.22
120
1109
9
114
0.79
0.20
5.6
5.6
—
—
—
0
0
12
144
0.83
0.19
1.0
1.1
—
—
—
0
0
339
3485
0.97
0.19
1.1
1.1
—
—
—
0
0
21
239
0.88
0.19
1.7
2.1
—
—
—
0
0
644
6563
0.98
0.19
1.3
1.3
—
—
—
0
0
60
559
1.07
0.19
1.4
1.6
5.8
5.8
mmol/l
0.02
47
455
41
447
0.92
0.19
1.0
1.1
0.1
2.5
nmol/l
—
6
78
15
175
0.86
0.18
1.0
1.0
—
—
—
0
0
10
81
1.23
0.18
1.0
1.1
—
—
—
0
0
33
299
1.10
0.18
1.1
1.2
—
—
—
0
0
128
1224
1.05
0.18
1.2
1.1
—
—
—
0
0
79
837
0.94
0.18
1.2
1.2
—
—
—
0
0
261
2533
1.03
0.18
2.0
2.2
4.4
5.0
umol/l
0.66
186
1839
12
100
1.20
0.18
1.2
1.3
—
—
—
0
0
170
1637
1.04
0.18
1.1
1.1
4.5
3.9
u/ml
0.22
65
673
37
403
0.92
0.17
1.5
1.4
—
—
—
0
0
76
719
1.06
0.16
1.0
1.0
1.3
0.7
u/ml
0.23
12
160
20
177
1.13
0.16
8.0
2.2
11.3
9.2
mmol/l
0.85
14
137
180
1741
1.03
0.16
1.1
1.1
3.7
4.4
u/ml
0.17
64
658
19
168
1.13
0.15
1.2
1.1
—
—
—
0
0
46
429
1.07
0.15
2.8
2.8
167.5
59.1
mg/l
0.40
32
301
312
3050
1.02
0.14
1.3
1.3
3.9
3.1
ug/l
0.32
287
2815
29
316
0.92
0.14
1.3
1.1
—
—
—
0
0
25
227
1.10
0.14
1.1
1.4
—
—
—
0
0
74
704
1.05
0.14
1.3
1.3
—
—
—
0
0
64
675
0.95
0.14
1.3
1.2
—
—
—
0
0
165
1702
0.97
0.14
1.1
1.2
3.5
3.6
mmol/l
0.46
159
1596
12
103
1.17
0.13
1.8
2.8
—
—
—
0
0
120
1158
1.04
0.13
1.2
1.3
—
—
—
0
0
126
1304
0.97
0.13
1.4
1.4
30.8
31.7
nmol/l
0.14
119
1197
25
273
0.92
0.13
2.5
2.4
594.4
621.9
ml
0.18
20
218
126
1302
0.97
0.12
1.4
1.3
1.5
1.3
nmol/l
0.35
106
1072
26
282
0.92
0.12
1.1
1.2
—
—
—
0
0
276
2704
1.02
0.12
1.5
1.5
0.5
0.5
nmol/l
0.32
223
2188
39
415
0.94
0.11
1.3
1.2
63.4
71.2
%
—
7
43
237
2319
1.02
0.11
1.1
1.1
0.9
1.1
u/ml
0.30
91
867
54
513
1.05
0.11
1.2
1.2
219.1
196.8
titre
0.07
11
102
165
1694
0.97
0.11
1.2
1.4
704.7
3628.9
e6/l
0.73
132
1397
158
1623
0.97
0.11
1.1
1.1
—
—
—
0
0
14
124
1.13
0.11
2.5
2.4
407.0
786.3
e6/l
—
8
87
165
1693
0.97
0.11
1.2
1.3
86.3
24.0
e6/l
0.39
128
1326
61
584
1.04
0.10
1.1
1.2
—
—
—
0
0
195
1909
1.02
0.09
1.3
1.3
1291.8
950.7
titre
0.33
11
85
67
644
1.04
0.09
1.0
1.1
8.6
7.6
iu/ml
0.18
21
203
163
1668
0.98
0.09
3.3
2.7
—
—
—
0
0
30
281
1.07
0.09
1.3
1.2
—
—
—
0
0
23
248
0.93
0.09
1.7
1.5
2.4
4.5
%
—
5
50
1245
12536
0.99
0.09
3.9
4.0
12.3
10.2
mg/mmol
0.48
779
7798
77
797
0.97
0.09
1.2
1.5
—
—
—
0
0
55
527
1.04
0.09
1.1
1.2
7.0
16.5
u/ml
—
6
63
213
2091
1.02
0.08
1.0
1.1
5.4
4.9
u/ml
0.18
99
1082
195
1914
1.02
0.08
1.2
1.3
524.0
455.0
mg/l
0.36
187
1834
200
1964
1.02
0.08
1.0
1.1
1.5
0.9
u/ml
0.39
73
802
5
65
0.77
0.08
1.0
1.2
—
—
—
0
0
43
450
0.96
0.08
1.0
1.1
13.1
9.8
u/ml
—
6
84
705
6991
1.01
0.08
2.0
2.0
387.5
376.8
nmol/l
0.77
653
6446
6
73
0.82
0.07
1.5
1.6
—
—
—
0
0
61
589
1.04
0.07
2.0
1.6
—
—
—
0
0
38
398
0.95
0.07
2.0
1.6
1.4
16.6
nmol/l
0.59
32
325
76
783
0.97
0.07
1.6
1.5
368.9
389.5
pmol/l
0.11
62
624
36
343
1.05
0.07
1.1
1.1
—
—
—
0
0
35
367
0.95
0.07
1.3
1.2
—
—
—
0
0
24
255
0.94
0.07
1.0
1.1
—
—
—
0
0
162
1592
1.02
0.06
1.2
1.3
—
—
—
0
0
17
183
0.93
0.06
1.1
1.5
—
—
—
0
0
1201
11949
1.01
0.06
1.6
1.6
31831979.4
28013428.5
pmol/l
0.10
1021
10463
9
105
0.86
0.06
1.1
1.1
—
—
—
0
0
72
740
0.97
0.06
2.4
2.4
1.4
1.4
mmol/l
0.18
72
721
14
152
0.92
0.06
1.1
1.0
—
—
—
0
0
97
992
0.98
0.06
2.1
2.2
—
—
—
0
0
147
1495
0.98
0.06
3.3
2.6
24.8
24.7
mmol/l
0.22
140
1396
51
494
1.03
0.05
2.4
2.5
—
—
—
0
0
146
1438
1.02
0.05
3.2
3.7
36.1
26.5
u/ml
0.51
136
1390
51
524
0.97
0.04
3.0
2.5
565.8
509.2
e6/l
0.60
45
426
16
170
0.94
0.04
1.1
1.1
—
—
—
0
0
53
517
1.03
0.04
1.2
1.5
—
—
—
0
0
20
190
1.05
0.04
1.6
2.0
—
—
—
0
0
23
220
1.05
0.03
1.3
1.4
27432.9
79434.4
e6/l
0.71
17
119
48
492
0.98
0.03
1.1
1.1
—
—
—
0
0
71
697
1.02
0.03
1.1
1.0
—
—
—
0
0
80
813
0.98
0.03
1.0
1.1
196.0
205.0
mg/l
0.35
65
717
11
102
1.08
0.03
1.2
1.1
—
—
—
0
0
16
168
0.95
0.02
1.2
1.1
—
—
—
0
0
16
168
0.95
0.02
1.2
1.1
—
—
—
0
0
16
168
0.95
0.02
1.2
1.1
—
—
—
0
0
10
107
0.93
0.02
2.6
2.5
—
—
—
0
0
83
838
0.99
0.01
1.1
1.2
32.0
35.6
mg/l
0.56
60
710
86
852
1.01
0.01
1.7
1.6
—
—
—
0
0
33
323
1.02
0.01
1.4
1.6
1.9
2.4
u/field
0.29
21
236
14
134
1.04
0.00
1.1
1.1
—
—
—
0
0
24
246
0.98
0.00
1.2
1.2
27.8
14.0
%
—
5
38
51
516
0.99
0.00
3.1
2.5
0.2
0.2
e9/l
0.26
46
427
264
2646
1.00
0.00
1.8
1.9
20.6
20.6
s
0.01
219
2210
18
177
1.02
0.00
3.2
2.2
—
—
—
0
0
22
217
1.01
0.00
2.5
3.0
7.4
7.4
ph
0.09
11
48
16
156
1.03
0.00
1.7
1.6
—
—
—
0
0
64
637
1.00
0.00
1.3
1.3
—
—
—
0
0
25
246
1.02
0.00
1.0
1.1
—
3.6
iu/ml
—
0
17
35
346
1.01
0.00
1.1
1.1
—
—
—
0
0
36
356
1.01
0.00
1.2
1.1
—
—
—
0
0
40
404
0.99
0.00
1.7
1.8
5.2
1.9
u/field
0.88
20
206
43
434
0.99
0.00
1.5
1.4
4.3
5.2
u/l
1.86
33
374
13
125
1.04
0.00
1.2
1.2
—
—
—
0
0
14
145
0.97
0.00
1.1
1.1
—
213.3
—
0
9
103
1035
1.00
0.00
2.9
2.8
0.9
0.8
nmol/l
0.71
90
872
37
369
1.00
0.00
1.0
1.0
—
—
—
0
0
68
679
1.00
0.00
2.5
2.5
6.8
7.1
mmol/l
0.48
68
662
11
111
0.99
0.00
2.9
2.2
1075.0
23899.0
e6/l
—
5
60
10
101
0.99
0.00
3.7
2.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
8
89
0.90
0.00
1.5
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
25
250
1.00
0.00
1.2
1.2
6.4
5.6
nmol/l
0.63
25
236
6
61
0.98
0.00
12.3
8.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
1398.9
—
0
9
7
77
0.91
0.00
3.0
7.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
0.5
—
0
7

Mortality – FinRegistry

Association

Association between endpoint N14_CERVICAL_HSIL and mortality.

Females

Parameter HR [95% CI] p-value
N14_CERVICAL_HSIL 1.314 [1.17, 1.48] < 0.001
Birth year 0.991 [0.98, 1.0] 0.045

During the follow-up period (1.1.1998 — 31.12.2019), 1401 out of 43721 females with N14_CERVICAL_HSIL died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_CERVICAL_HSIL.

N-year risk Females Males
1 0.103% No data
5 0.634% No data
10 1.524% No data
15 3.107% No data
20 5.718% No data

Relationships between endpoints

Index endpoint: N14_CERVICAL_HSIL – HSIL lesion of the cervix uteri

GWS hits: 4

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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