hematologic disease: A disease involving the hematopoietic system.
Other and unspecified diseases of blood and blood-forming organs
DOID EFO Endpoint Browser PheWeb
D3_BLOODNAS
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
983 |
4. Check minimum number of eventsNone |
983 |
5. Include endpointsNone |
983 |
6. Filter based on genotype QC (FinnGen only) |
957 |
Control definitions (FinnGen only)
- Control exclude
- D3_BLOODOTHER
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other and unspecified diseases of blood and blood-forming organs
based on the number of shared cases.
Similar with more cases:
- Other diseases of blood and blood-forming organs
- Other diseases of blood and blood-forming organs, wide
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6321 | 3318 | 2939 |
| Only index persons | 5103 | 2725 | 2378 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.10 | 0.08 |
| Only index persons | 0.10 | 0.10 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 59.07 | 58.15 | 60.11 |
| Only index persons | 57.37 | 55.93 | 59.01 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 957 | 509 | 448 |
| Unadjusted period prevalence (%) | 0.19 | 0.18 | 0.21 |
| Median age at first event (years) | 60.15 | 58.01 | 62.58 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 983
- Matched controls
- 9830
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
79.4
307.7
187
29
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
22.7
307.7
279
169
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
4503599627370496.0
307.7
772
*
XW000
NOMESCO Finland
Bone marrow biopsy
38.4
307.7
370
152
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
116.6
307.5
157
16
L01XX05
ATC
hydroxycarbamide; oral
57.7
301.6
172
36
D45
ICD-10 Finland
Polycythaemia vera
38.3
160.3
100
29
D75.8
ICD-10 Finland
Other specified diseases of blood and blood-forming organs
839.9
150.4
144
*
D75.2
ICD-10 Finland
Essential thrombocytosis
686.4
125.3
121
*
TPH00
NOMESCO Finland
Phlebotomy
49.9
89.3
52
11
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.2
76.6
248
724
9962/3-C42.1
ICD-O-3
Essential thrombocythemia of bone marrow
185.3
66.9
69
*
D75.1
ICD-10 Finland
Secondary polycythaemia
182.8
50.4
52
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.7
44.3
156
472
Z2221
NOMESCO Finland
Medical doctor
2.6
41.0
354
1767
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
40.1
552
3397
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
146.1
40.1
42
*
28998
ICD-8 Finland
Other disease of blood and blood-forming organs, Alii definiti
+∞
38.8
37
*
D64.9
ICD-10 Finland
Anaemia, unspecified
3.2
35.5
157
546
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
8.2
34.7
47
60
28999
ICD-8 Finland
Other disease of blood and blood-forming organs, Other and unspecified
+∞
34.6
33
*
SPAT1074
SPAT
Venesection
36.5
33.0
42
12
WW500
NOMESCO Finland
Blood transfusion
4.7
31.1
75
170
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
88.0
30.9
34
*
R4110
NOMESCO Finland
Physiotherapy
2.2
28.3
332
1841
C90.0
ICD-10 Finland
Multiple myeloma
9.7
27.2
32
34
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
8.2
26.1
35
44
9950/3-C42.1
ICD-O-3
Polycythemia vera of bone marrow
40.0
25.0
31
8
D75.0
ICD-10 Finland
Familial erythrocytosis
256.3
24.8
25
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
66.6
22.9
26
*
ZX120
NOMESCO Finland
Intravenous
2.8
22.9
127
497
Z3226
NOMESCO Finland
Physiotherapist
2.3
22.8
219
1106
M04AA01
ATC
allopurinol; systemic
2.5
22.6
166
746
ZXE00
NOMESCO Finland
One hour or less
2.0
22.5
417
2689
9960/3-C42.1
ICD-O-3
Myeloproliferative neoplasm, NOS, of bone marrow
82.0
21.8
24
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
21.4
195
961
WW200
NOMESCO Finland
Immunization
5.2
21.1
44
88
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
20.8
327
1980
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
20.0
200
1023
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
75.1
19.8
22
*
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
25.2
19.6
27
11
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.8
19.1
101
384
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.5
19.1
128
549
L01XX35
ATC
anagrelide; oral
193.5
18.6
19
*
B99
ICPC
Blood/lymph/spleen disease other
33.6
18.0
23
7
D64.8
ICD-10 Finland
Other specified anaemias
6.0
18.0
32
55
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
17.8
244
1397
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
19.0
17.4
26
14
H02AB06
ATC
prednisolone; systemic
1.8
17.2
483
3458
L03AB05
ATC
interferon alfa-2b; parenteral
32.1
17.1
22
7
Z3231
NOMESCO Finland
Registered nurse
1.9
17.1
291
1791
TPH00, ,
SPAT
64.5
16.8
19
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
16.8
397
2699
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
16.3
381
2575
189
Kela drug reimbursment
Imatinib
61.0
15.8
18
*
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
13.2
15.7
27
21
L03AA02
ATC
filgrastim; parenteral
4.1
15.7
44
112
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.1
15.6
68
232
WX402
NOMESCO Finland
General anaesthesia
1.9
14.6
215
1253
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
14.3
207
1199
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
19.5
14.3
21
11
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
14.2
128
622
XF600
NOMESCO Finland
Bloodpressure measurement
2.7
14.1
80
315
C03CA01
ATC
furosemide; systemic
1.8
14.1
309
2034
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
14.0
236
1436
B01AB05
ATC
enoxaparin; parenteral
1.7
13.7
324
2174
374
Kela drug reimbursment
Ruxolitinib
76.2
13.6
15
*
174
Kela drug reimbursment
Ruxolitinib
76.2
13.6
15
*
R50.9
ICD-10 Finland
Fever, unspecified
2.0
13.5
156
834
316
Kela drug reimbursment
Imatinib
141.9
13.5
14
*
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
141.9
13.5
14
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
13.4
172
954
WX002
NOMESCO Finland
Sedation and analgesia
1.9
13.4
212
1261
L01EA01
ATC
imatinib; oral
50.7
12.9
15
*
WX892
NOMESCO Finland
Monitored bed care
2.4
12.8
91
399
A02BC02
ATC
pantoprazole; systemic
1.7
12.8
664
5430
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
12.6
126
637
L01EJ01
ATC
ruxolitinib; oral
70.8
12.6
14
*
2898X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Other specified diseases of blood and blood-forming organs
+∞
12.5
12
*
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
10.7
12.3
23
22
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
12.2
335
2327
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.6
12.2
74
302
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.5
12.0
41
120
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.6
12.0
72
292
UJF30
NOMESCO Finland
Ileoscopy through colon
2.2
11.8
111
549
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.6
11.7
68
271
L04AD01
ATC
ciclosporin; systemic
4.3
11.6
30
72
UJF92
NOMESCO Finland
Capsular endoscopy
4.3
11.6
30
72
D70.82
ICD-10 Finland
Drug-induced neutropenia
+∞
11.5
11
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.3
11.2
86
391
R72
ICD-10 Finland
Abnormality of white blood cells, not elsewhere classified
20.3
11.1
16
8
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.7
11.0
35
98
212
Kela drug reimbursment
Gout
4.3
10.9
28
67
R11
ICD-10 Finland
Nausea and vomiting
2.2
10.8
92
437
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
4.8
10.8
24
51
JN4BD
NOMESCO Finland
Extensive body CT
2.1
10.7
111
569
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.1
10.6
101
502
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
10.5
200
1250
R06.0
ICD-10 Finland
Dyspnoea
1.7
10.4
267
1808
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.0
10.4
45
153
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.1
10.4
110
568
R4190
NOMESCO Finland
Nutritional therapy
3.1
10.1
43
145
J01MA02
ATC
ciprofloxacin; systemic
1.6
10.0
370
2731
N02AX02
ATC
tramadol; systemic, rectal
1.6
10.0
421
3200
L03AB04
ATC
interferon alfa-2a; parenteral
26.3
9.8
13
5
B74
ICPC
Malignant neoplasm blood other
55.6
9.7
11
*
R4120
NOMESCO Finland
Occupational therapy
2.3
9.5
72
325
A04AA01
ATC
ondansetron; systemic, rectal
2.2
9.5
82
391
J01MA12
ATC
levofloxacin; systemic
1.7
9.5
184
1154
L01XE18
ATC
[U] ruxolitinib
101.0
9.4
10
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
9.4
252
1720
ZXD05
NOMESCO Finland
Urgent procedure
1.6
9.4
291
2057
2899X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Unspecified diseases of blood and blood-forming organs
+∞
9.4
9
*
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
+∞
9.4
9
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.0
9.3
97
499
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
9.2
183
1155
J01DB01
ATC
cefalexin; oral
1.7
9.2
781
6881
ZXA10
NOMESCO Finland
Bilateral
1.7
9.1
184
1165
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
7.1
9.1
21
30
L01XE01
ATC
[U] imatinib
37.0
9.0
11
*
ZXA00
NOMESCO Finland
Right side
1.6
9.0
266
1856
AA1AD
NOMESCO Finland
CT of head and brain
1.6
9.0
260
1805
C03DA01
ATC
spironolactone; oral
1.9
9.0
127
724
B03XA02
ATC
darbepoetin alfa; parenteral
3.6
8.8
29
83
TK800
NOMESCO Finland
Hemodialysis
3.6
8.8
29
83
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
10.8
8.8
16
15
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.5
8.8
55
228
Z2446
NOMESCO Finland
Social worker
2.2
8.8
71
330
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
8.6
322
2367
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
8.5
231
1576
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.0
8.5
89
458
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
20.2
8.5
12
6
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
90.8
8.4
9
*
C07AB07
ATC
bisoprolol; oral
1.5
8.4
466
3714
D72.1
ICD-10 Finland
Eosinophilia
+∞
8.3
8
*
B01AA03
ATC
warfarin; systemic
1.7
8.3
179
1152
T90
ICPC
Diabetes non-insulin dependent
1.6
8.3
228
1560
B01AB04
ATC
dalteparin; parenteral
2.5
8.3
52
216
R71
ICD-10 Finland
Abnormality of red blood cells
14.6
8.2
13
9
B03XA01
ATC
erythropoietin; parenteral
6.6
8.2
20
31
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
8.2
162
1020
H02AB07
ATC
prednisone; oral
1.8
8.0
132
788
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
8.0
417
3270
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
7.9
168
1076
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
7.8
7.9
17
22
R53
ICD-10 Finland
Malaise and fatigue
1.6
7.9
215
1468
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.2
7.8
62
286
S16
ICPC
Bruise/contusion
2.9
7.8
35
122
122
Kela drug reimbursment
Aplastic anaemia
45.3
7.7
9
*
M79.6
ICD-10 Finland
Pain in limb
1.5
7.7
382
2961
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.5
7.7
49
205
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.4
7.7
53
230
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
7.7
292
2145
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
7.7
179
1175
D07AC01
ATC
betamethasone; topical
1.5
7.6
327
2461
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
25.2
7.6
10
*
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
10.1
7.5
14
14
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.0
7.5
84
442
127
Kela drug reimbursment
Transplant complication
4.0
7.5
21
54
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
7.5
646
5558
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.1
7.4
70
346
R5110, ,
SPAT
2.1
7.4
68
333
J01CA04
ATC
amoxicillin; systemic
1.5
7.3
754
6704
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
7.3
110
639
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
11.0
7.3
13
12
D73.0
ICD-10 Finland
Hyposplenism
+∞
7.3
7
*
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.5
7.2
45
187
Z71.8
ICD-10 Finland
Other specified counselling
1.5
7.2
266
1940
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
20.2
7.1
10
5
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
8.0
7.1
15
19
N03AX16
ATC
[U] pregabalin
1.6
7.0
216
1511
R03AC02
ATC
salbutamol; inhalant
1.4
7.0
495
4078
3AC01, ,
NOMESCO Finland
6.4
7.0
17
27
L29
ICPC
Musculoskeletal sympt/complt other
1.9
6.9
82
441
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
6.9
134
837
P01AB01
ATC
metronidazole; oral, rectal
1.4
6.9
358
2785
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
6.9
228
1621
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
3.3
6.9
25
77
J01FA10
ATC
azithromycin; systemic
1.4
6.8
504
4177
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
8.3
6.8
14
17
UJF32
NOMESCO Finland
Coloscopy
1.5
6.8
245
1772
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
6.7
398
3168
SPAT1262
SPAT
Handing over of treatment supplies
1.6
6.7
162
1070
Z01.7
ICD-10 Finland
Laboratory examination
1.7
6.6
134
847
E66.8
ICD-10 Finland
Other obesity
2.3
6.6
50
227
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
3.9
6.6
19
50
A02BC01
ATC
omeprazole; systemic
1.5
6.5
252
1848
N06AX11
ATC
mirtazapine; oral
1.5
6.5
306
2333
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
6.4
566
4821
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
6.4
239
1740
A28
ICPC
Limited function/disability NOS
1.6
6.3
155
1027
B82
ICPC
Anaemia other/unspecified
2.9
6.3
29
103
ZXA05
NOMESCO Finland
Left side
1.5
6.3
229
1658
C91.4
ICD-10 Finland
Hairy-cell leukaemia
+∞
6.3
6
*
9940/3-C42.1
ICD-O-3
Hairy cell leukemia, NOS, of bone marrow
+∞
6.3
6
*
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
26.9
6.2
8
*
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
26.9
6.2
8
*
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
26.9
6.2
8
*
D58.2
ICD-10 Finland
Other haemoglobinopathies
26.9
6.2
8
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
6.2
455
3744
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
6.3
6.2
15
24
A41.9
ICD-10 Finland
Sepsis, unspecified
2.5
6.2
37
151
XCK10
NOMESCO Finland
Photography of fundus of eye
1.8
6.1
90
519
103
Kela drug reimbursment
Diabetes, insulin-treated
1.5
6.1
245
1806
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
6.1
199
1407
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.6
6.0
33
129
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
296
101
41.50
307.65
1.8
1.7
—
—
—
0
0
510
863
11.20
307.65
7.7
3.7
255.47
248.88
u/l
0.24
502
812
220
119
23.53
286.52
1.5
1.2
59.16
36.75
u/l
0.55
192
109
191
84
27.98
270.17
1.0
1.0
—
—
—
0
0
460
877
8.98
257.76
4.0
2.4
1.88
1.82
%
0.45
424
785
388
642
9.33
245.11
4.2
2.6
77.23
71.33
e9/l
1.55
254
498
386
1071
5.29
134.95
3.4
2.5
24.96
22.69
%
1.71
347
912
768
3731
5.84
130.03
14.0
5.7
2.81
2.88
%
0.39
742
3488
773
3833
5.76
125.85
14.2
5.8
28.51
27.60
%
1.25
748
3598
387
1140
4.95
124.39
3.3
2.4
2.32
2.33
g/l
0.10
371
1059
759
3791
5.40
120.04
13.6
5.5
56.21
57.41
%
1.73
732
3556
396
1250
4.63
115.28
3.4
2.4
13.91
12.84
umol/l
1.68
381
1165
781
4120
5.36
111.46
14.5
5.8
0.22
0.19
e9/l
1.26
701
3622
774
4078
5.22
109.99
13.3
5.7
2.34
1.92
e9/l
1.31
699
3609
156
231
7.84
103.37
5.2
2.6
0.06
0.02
g/l
0.38
148
217
163
254
7.49
103.17
5.1
2.9
2.02
1.25
g/l
0.88
152
232
188
348
6.44
100.76
2.8
1.8
1.25
1.53
g/l
3.04
166
302
148
219
7.78
97.97
5.0
2.6
0.00
0.00
g/l
-0.00
140
205
167
284
6.88
97.17
5.1
2.6
3.03
2.98
g/l
0.21
159
261
145
217
7.67
94.93
5.1
2.7
0.00
0.00
g/l
-0.00
140
204
802
4627
4.98
93.59
20.7
8.5
4.62
4.13
e9/l
2.84
716
4039
150
244
7.07
90.85
5.0
2.5
38.07
37.70
g/l
0.26
142
221
168
307
6.39
90.82
5.0
2.5
—
—
—
0
0
168
307
6.39
90.82
5.0
2.5
3.69
3.57
g/l
0.43
160
284
168
307
6.39
90.82
5.0
2.5
6.92
7.39
g/l
2.43
160
284
158
285
6.41
86.38
4.9
2.5
10.54
10.59
g/l
0.04
149
261
94
95
10.84
83.80
2.8
2.2
32.67
33.00
pg
0.24
94
95
143
248
6.58
81.14
5.5
3.6
50.34
80.02
mg/l
0.57
129
204
143
249
6.55
80.80
5.5
3.6
66.16
41.97
mg/l
0.60
129
207
237
661
4.41
77.90
4.2
2.9
66.88
66.70
g/l
0.12
223
607
139
244
6.47
77.83
5.5
3.6
11.83
1.84
ratio
—
7
26
469
2091
3.38
76.12
4.3
2.6
3061.66
7432.23
umol/l
1.55
436
1822
212
597
4.25
68.15
3.0
2.6
11.18
10.92
g/l
0.19
197
543
125
225
6.22
67.99
3.2
2.1
91.06
90.21
%
0.14
117
217
183
471
4.55
66.08
2.4
1.7
1.65
1.53
g/l
0.18
168
433
437
2002
3.13
65.50
8.0
3.9
86.67
90.45
%
2.21
421
1955
693
4203
3.20
61.35
10.6
6.1
11.23
11.51
umol/l
0.36
677
4005
428
2010
3.00
60.29
3.0
2.1
3.37
3.04
mg/l
0.80
366
1698
105
186
6.20
57.83
1.6
1.6
—
—
—
0
0
54
42
13.55
56.66
1.6
1.4
—
—
—
0
0
54
42
13.55
56.66
1.6
1.4
—
—
—
0
0
589
3366
2.87
56.21
5.0
2.7
176.54
133.50
ug/l
1.13
558
3095
607
3634
2.75
51.05
9.6
6.0
1.22
1.21
mmol/l
0.86
576
3312
589
3475
2.73
50.98
8.0
4.7
35.34
35.47
g/l
0.23
559
3248
241
892
3.25
50.25
5.6
2.9
6.07
8.81
umol/l
2.92
214
784
104
224
5.07
46.11
1.3
1.3
—
—
—
0
0
632
3999
2.63
45.23
10.5
6.9
1.21
1.21
mmol/l
0.04
530
3429
261
1074
2.95
44.72
7.6
5.7
1.06
1.03
mmol/l
0.82
250
989
829
6221
3.12
38.91
15.6
7.4
80.52
78.32
u/l
0.87
804
5836
409
2237
2.42
38.30
4.1
3.1
0.68
0.45
e6/l
0.79
312
1721
432
2446
2.37
37.11
4.2
3.3
46.77
93.51
e6/l
0.80
331
1910
76
152
5.34
36.52
4.8
3.5
57.95
58.09
%
0.02
76
152
67
121
5.87
35.93
1.4
1.4
83.38
111.19
u/ml
—
8
21
72
147
5.21
33.78
3.6
3.2
5.00
4.29
e9/l
0.84
72
147
265
1248
2.54
33.73
3.6
2.0
30.32
29.77
s
0.87
256
1209
299
1502
2.42
32.98
2.1
1.4
2.45
2.51
g/l
0.16
208
912
271
1304
2.49
32.84
3.5
3.0
1.86
2.35
e6/l
0.56
147
732
182
724
2.86
32.29
2.7
2.4
36.08
33.79
u/l
0.23
160
607
522
3330
2.21
32.28
2.6
2.0
89.83
94.82
pmol/l
1.88
327
1698
35
6
60.39
30.27
1.1
1.2
—
—
—
0
0
40
50
8.30
30.04
1.2
1.3
—
—
—
0
0
430
2605
2.16
29.55
5.3
3.3
33.77
33.03
u/l
0.13
416
2479
293
1529
2.31
29.07
4.8
4.0
104.48
465.46
ng/l
2.97
241
1205
261
1305
2.36
28.53
4.7
3.3
0.81
0.81
mmol/l
0.08
252
1226
345
1938
2.20
28.52
2.0
1.5
20.73
20.79
nmol/l
0.03
321
1630
775
5955
2.42
28.52
5.5
4.1
15.82
12.36
mm/h
5.13
733
5476
68
153
4.70
28.43
5.5
5.8
1046.22
393.63
iu/ml
—
9
19
317
1754
2.19
26.94
2.5
1.6
1.41
1.15
mg/l
0.85
264
1345
25
0
+∞
26.16
7.6
0.0
—
—
—
0
0
63
145
4.57
25.60
1.3
1.2
—
—
—
0
0
35
14
25.85
25.40
1.1
1.5
—
—
—
0
0
280
1525
2.17
24.39
1.9
1.7
1096.78
1188.33
nmol/l
0.78
212
1156
257
1388
2.15
22.65
3.3
2.8
0.80
1.18
e6/l
1.17
135
815
272
1517
2.10
21.95
3.5
3.0
2.45
2.45
mmol/l
0.29
244
1332
294
1691
2.05
21.81
3.2
2.5
4.00
5.10
e6/l
1.65
263
1532
57
140
4.26
21.32
1.4
1.2
231.39
279.90
u/ml
0.51
36
81
630
4723
1.93
20.92
8.7
4.9
6.72
6.72
mmol/l
0.02
606
4450
157
714
2.43
20.69
10.3
7.6
9.99
9.70
mmol/l
0.19
150
678
24
5
49.11
20.22
1.1
1.0
—
—
—
0
0
134
580
2.52
19.61
2.1
1.6
—
—
—
0
0
50
120
4.34
19.27
6.2
3.4
1.13
1.28
%
0.13
39
111
28
40
7.18
18.73
2.1
2.1
—
—
—
0
0
410
2747
1.84
18.70
4.2
3.3
2.34
2.35
mmol/l
0.91
376
2405
38
75
5.23
18.47
2.0
2.0
—
—
—
0
0
537
3931
1.81
18.07
3.8
3.7
0.00
0.00
estimate
0.50
138
708
823
6912
2.17
18.04
40.7
16.9
15.33
14.99
%
1.24
817
6789
72
235
3.23
17.78
2.2
1.6
0.25
0.23
g/l
0.67
65
225
531
3888
1.80
17.72
5.2
5.1
0.00
0.00
estimate
0.50
144
726
520
3786
1.79
17.67
21.2
14.9
1.25
1.25
inr
0.02
169
1101
28
43
6.67
17.54
2.0
2.2
691.52
522.06
e6/l
0.60
23
35
53
147
3.75
16.80
1.5
1.3
—
—
—
0
0
53
147
3.75
16.80
1.5
1.3
—
—
—
0
0
36
74
5.01
16.72
1.1
1.1
—
—
—
0
0
72
244
3.11
16.70
2.3
1.6
1.25
1.16
g/l
1.32
66
232
525
3886
1.75
16.37
3.7
3.8
0.00
0.00
estimate
0.50
144
777
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
76
272
2.94
16.03
4.5
2.7
0.32
0.36
u/ml
0.44
45
149
661
5257
1.79
15.74
5.5
4.5
349.50
2838.23
e6/l
—
6
88
172
906
2.09
15.64
2.2
1.8
—
—
—
0
0
901
7973
2.56
15.54
29.1
14.2
22.06
24.18
mg/l
1.29
791
6318
172
911
2.08
15.40
2.2
1.8
—
—
—
0
0
361
2441
1.76
15.17
2.4
2.1
166.02
233.02
u/l
1.09
341
2305
76
284
2.82
14.82
1.5
1.6
—
180.00
—
0
9
152
782
2.12
14.66
3.1
2.3
0.21
0.21
g/l
0.20
137
732
220
1293
1.90
14.56
2.3
1.8
—
—
—
0
0
30
61
5.04
14.12
1.2
1.1
270.00
85.45
titre
—
6
11
327
2192
1.74
13.92
1.8
1.6
1.54
1.39
mmol/l
2.34
256
1834
97
428
2.40
13.50
11.1
12.0
—
—
—
0
0
291
1933
1.72
12.57
5.3
2.3
—
—
—
0
0
23
41
5.72
12.46
1.6
1.1
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
23
22
10.68
12.29
1.5
2.9
146.09
124.00
%
0.51
23
22
443
3299
1.62
12.20
3.0
2.2
78.58
76.96
nmol/l
0.58
404
2934
18
10
18.31
12.07
1.1
1.2
—
—
—
0
0
155
863
1.95
11.89
4.2
3.2
—
—
—
0
0
139
750
1.99
11.67
5.8
3.7
0.91
1.95
mmol/l
1.83
115
620
38
109
3.59
11.51
1.4
1.2
1.44
2.30
u/ml
0.61
16
33
39
114
3.52
11.48
1.4
1.2
4.95
6.02
u/ml
0.15
22
42
11
0
+∞
11.48
1.2
0.0
—
—
—
0
0
139
759
1.97
11.26
5.8
3.7
5.82
5.77
kpa
0.23
132
737
161
938
1.86
10.70
9.0
8.3
0.25
1.21
mmol/l
1.97
142
742
132
722
1.96
10.62
2.5
2.0
334.96
377.65
nmol/l
1.90
125
666
631
5255
1.56
9.83
4.5
3.1
61.11
49.68
u/l
1.41
601
4893
21
43
4.97
9.82
2.5
1.2
11.31
5.89
ug/l
1.28
21
37
121
664
1.94
9.62
3.1
2.9
221.39
204.80
ng/l
0.17
111
611
40
1017
0.37
9.42
7.7
7.2
—
—
—
0
0
96
491
2.06
9.31
2.1
1.7
—
—
—
0
0
34
105
3.32
9.24
1.2
1.1
—
—
—
0
0
28
76
3.76
9.21
2.7
2.2
—
—
—
0
0
822
7353
1.72
8.98
5.5
4.7
1.91
2.10
mu/l
0.56
764
6689
902
8308
2.04
8.83
30.3
16.5
139.37
139.69
mmol/l
3.05
888
8094
26
70
3.79
8.65
1.2
1.2
—
—
—
0
0
903
8331
2.03
8.63
32.3
16.6
3.98
3.98
mmol/l
0.02
887
8100
117
658
1.88
8.63
5.2
3.7
1.23
1.23
mmol/l
0.04
96
572
842
7608
1.74
8.53
29.0
13.0
79.88
79.96
ml/min/173m2
0.03
744
6257
45
173
2.68
8.37
1.6
1.5
—
—
—
0
0
22
54
4.14
8.29
1.5
3.0
41.60
41.49
%
—
5
31
96
512
1.97
8.29
12.2
10.0
93.59
94.07
%
0.30
96
507
114
646
1.87
8.21
5.1
3.8
105.57
88.43
ng/l
1.02
103
569
55
236
2.41
8.17
1.8
1.6
—
—
—
0
0
469
3761
1.47
8.06
5.0
2.5
—
—
—
0
0
15
16
9.50
7.79
1.0
1.0
—
—
—
0
0
342
2599
1.48
7.60
4.6
3.8
20.68
9.22
mg/mmol
1.87
217
1633
71
350
2.11
7.60
2.0
2.1
38.24
38.43
u/l
0.02
61
312
341
2605
1.47
7.32
4.3
3.1
7.48
7.55
mmol/l
0.10
273
2193
11
7
15.86
7.24
1.2
1.1
—
—
—
0
0
697
6104
1.49
7.22
4.5
3.9
14.81
14.84
pmol/l
0.11
627
5534
913
8533
1.98
7.21
20.8
10.3
27.08
26.26
u/l
0.77
888
8223
324
2460
1.47
7.14
4.2
3.2
788.77
255.44
mg/l
0.90
222
1577
35
129
2.78
7.09
1.3
1.3
—
—
—
0
0
54
246
2.26
7.04
1.5
1.6
0.04
0.09
iu/ml
0.41
17
44
20
52
3.91
7.00
1.2
1.2
—
—
—
0
0
20
52
3.91
7.00
1.2
1.2
—
—
—
0
0
821
7463
1.61
7.00
6.8
5.9
39.80
39.94
mmol/mol
0.16
768
6910
17
39
4.42
6.98
1.2
1.1
—
—
—
0
0
20
53
3.83
6.83
1.2
1.2
—
—
—
0
0
20
53
3.83
6.83
1.2
1.2
—
—
—
0
0
20
53
3.83
6.83
1.2
1.2
—
—
—
0
0
316
2405
1.46
6.82
3.7
3.0
2210.40
1324.77
ng/l
1.75
260
2059
10
6
16.82
6.75
1.0
1.0
—
—
—
0
0
27
89
3.09
6.66
1.5
1.6
—
—
—
0
0
27
89
3.09
6.66
1.5
1.6
—
—
—
0
0
45
195
2.37
6.59
1.6
1.3
8.38
9.74
u/l
0.30
30
159
17
31
5.56
6.32
1.2
1.5
65.50
72.74
mg/l
0.17
12
23
27
92
2.99
6.31
1.6
1.7
—
—
—
0
0
56
272
2.12
6.26
1.6
1.3
21.05
27.40
iu/l
0.97
44
234
24
77
3.17
6.19
7.5
3.0
58.87
55.27
%
0.22
15
69
52
248
2.16
6.10
2.3
1.7
—
—
—
0
0
79
443
1.85
5.90
3.0
3.4
4.39
4.51
pmol/l
0.49
71
389
42
186
2.31
5.88
1.8
1.6
—
—
—
0
0
32
126
2.59
5.75
1.7
1.6
—
—
—
0
0
32
126
2.59
5.75
1.7
1.6
—
—
—
0
0
42
189
2.28
5.68
1.7
1.6
—
—
—
0
0
140
930
1.59
5.65
2.5
2.3
160.75
123.98
ug/g
0.41
116
741
38
164
2.37
5.64
4.9
2.3
16.11
16.15
%
0.01
23
88
44
208
2.17
5.30
1.4
1.2
—
23.86
—
0
14
9
8
11.34
5.29
1.1
1.0
103.22
111.00
%
—
9
8
14
26
5.45
5.23
1.1
2.5
—
73835.50
—
0
6
26
100
2.64
4.92
1.5
1.2
0.72
0.62
nmol/l
0.53
26
94
17
51
3.37
4.90
1.6
1.4
12.06
14.00
u/l
0.51
17
46
23
84
2.78
4.80
2.8
4.0
—
—
—
0
0
43
211
2.09
4.74
1.2
1.1
—
—
—
0
0
226
1715
1.41
4.72
1.4
1.2
2.20
1.72
u/ml
0.16
43
472
20
69
2.94
4.62
1.2
1.0
—
—
—
0
0
47
241
2.00
4.61
1.5
1.2
—
—
—
0
0
43
215
2.05
4.53
1.4
1.3
—
—
—
0
0
8
8
10.07
4.52
1.0
2.3
—
—
—
0
0
314
2538
1.35
4.41
3.0
2.5
53.69
90.16
u/l
0.61
290
2358
25
101
2.51
4.32
1.3
1.3
—
—
—
0
0
14
41
3.45
4.19
1.1
1.2
—
—
—
0
0
31
142
2.22
4.09
6.9
1.9
63.20
60.65
%
0.24
31
142
96
635
1.57
3.96
4.2
2.9
4.69
4.57
kpa
0.20
89
613
64
1025
0.60
3.90
4.8
4.6
29.00
32.28
%
2.00
50
691
539
4755
1.30
3.89
3.2
2.8
—
—
—
0
0
7
8
8.80
3.77
1.1
1.0
—
—
—
0
0
29
135
2.18
3.70
1.3
1.1
—
—
—
0
0
179
1358
1.39
3.69
1.3
1.3
37.30
32.30
iu/ml
0.12
54
439
47
265
1.81
3.54
2.3
3.0
—
—
—
0
0
86
576
1.54
3.39
3.6
2.3
12.68
13.08
nmol/l
0.17
80
514
23
102
2.28
3.31
1.3
1.4
1036.35
1600.01
e6/l
0.79
17
69
857
8136
1.42
3.30
5.9
5.0
2.58
2.74
mmol/l
5.64
812
7472
35
184
1.94
3.28
3.1
2.1
132.46
130.09
g/l
0.15
26
135
838
7934
1.38
3.21
5.3
4.4
1.31
1.47
mmol/l
24.89
794
7279
15
55
2.75
3.16
2.4
1.8
0.87
1.02
g/l
0.61
15
55
354
3019
1.27
3.15
3.9
3.9
—
—
—
0
0
14
50
2.83
3.09
1.5
2.0
—
—
—
0
0
829
7846
1.36
3.09
5.0
4.6
5.99
5.98
mmol/l
0.09
758
7133
24
112
2.17
3.08
1.4
1.4
29.03
31.68
g/l
0.44
19
98
24
112
2.17
3.08
1.6
1.5
—
—
—
0
0
33
174
1.93
3.08
1.6
1.3
130.86
742.71
e6/l
0.47
28
140
33
174
1.93
3.08
1.6
1.3
4.25
61.39
e6/l
0.98
28
135
6
8
7.54
3.06
1.0
1.0
—
—
—
0
0
21
93
2.29
3.05
1.3
1.4
213095.50
37777.88
e6/l
0.63
14
51
42
245
1.75
2.87
1.3
1.5
290.21
288.98
ug/g
0.01
24
146
164
1278
1.34
2.85
1.3
1.3
20.80
11.80
u/ml
0.47
44
487
809
7653
1.32
2.83
4.7
4.0
1.44
1.29
mmol/l
5.48
764
6978
71
476
1.53
2.82
1.6
1.4
—
—
—
0
0
8
18
4.47
2.80
1.5
1.4
106.25
69.56
nmol/24h
—
8
18
214
1736
1.30
2.79
1.7
1.7
35151997.16
35978160.00
pmol/l
0.01
165
1437
12
39
3.10
2.77
1.2
1.2
—
—
—
0
0
116
860
1.40
2.75
3.0
4.1
3.42
24.66
ug/l
1.49
93
708
838
7981
1.34
2.69
5.5
4.5
4.34
4.64
mmol/l
13.64
803
7373
253
2107
1.27
2.67
4.2
4.0
0.00
0.01
estimate
0.69
132
709
71
482
1.51
2.67
1.3
1.3
46.80
53.20
au/ml
—
5
33
70
476
1.51
2.62
1.5
1.2
187.79
231.72
u/ml
0.21
61
433
918
8884
1.50
2.62
46.1
21.0
40.07
40.16
%
0.14
867
8280
918
8888
1.50
2.57
45.5
20.8
311.31
248.39
e9/l
28.29
896
8662
6
11
5.48
2.54
4.2
6.0
—
—
—
0
0
918
8891
1.49
2.53
45.4
20.8
4.47
4.49
e12/l
0.33
895
8640
918
8893
1.49
2.50
45.8
21.0
132.89
135.36
g/l
3.17
909
8753
11
37
2.99
2.49
1.0
1.1
—
—
—
0
0
26
137
1.92
2.47
1.9
1.7
—
—
—
0
0
159
1263
1.31
2.42
1.6
1.4
—
—
—
0
0
11
38
2.92
2.42
1.2
1.0
—
—
—
0
0
92
672
1.41
2.40
3.1
2.6
60.97
66.19
ml/min/173m2
0.70
58
270
122
936
1.35
2.36
1.8
1.8
1.62
1.50
%
0.96
100
816
12
47
2.57
2.27
1.6
1.3
—
—
—
0
0
7
18
3.91
2.25
2.0
1.8
—
—
—
0
0
16
73
2.21
2.22
1.3
1.8
—
—
—
0
0
72
514
1.43
2.15
1.3
1.2
177.74
151.18
iu/ml
0.19
29
205
26
146
1.80
2.08
1.5
1.5
—
—
—
0
0
7
20
3.52
2.05
1.1
1.1
—
—
—
0
0
39
248
1.60
2.01
1.7
2.1
—
—
—
0
0
9
32
2.83
2.00
2.0
2.3
17.54
278.30
ug/l
—
9
27
17
84
2.04
1.96
1.0
1.1
—
—
—
0
0
5
11
4.56
1.94
5.0
5.7
5.10
6.75
mmol/l
—
5
11
22
120
1.85
1.94
1.0
1.1
—
—
—
0
0
31
188
1.67
1.92
4.4
2.7
8.09
8.06
kpa
0.03
31
181
15
72
2.10
1.87
1.0
1.1
—
—
—
0
0
70
513
1.39
1.84
3.9
3.6
2.08
1.85
mmol/l
0.19
50
380
6
17
3.54
1.84
1.3
1.3
—
—
—
0
0
38
247
1.56
1.81
1.2
1.2
—
—
—
0
0
30
186
1.63
1.74
1.9
1.4
—
—
—
0
0
14
68
2.07
1.70
1.3
1.2
—
—
—
0
0
30
189
1.61
1.64
1.5
1.9
2.97
5.00
iu/l
—
8
64
10
42
2.40
1.62
1.4
1.3
178.80
160.99
mmol/24h
—
10
42
5
14
3.58
1.61
2.0
1.4
—
—
—
0
0
184
1563
1.22
1.60
2.9
3.0
0.62
0.75
ug/l
1.74
132
1042
8
32
2.51
1.60
3.3
3.9
—
—
—
0
0
19
107
1.79
1.55
1.2
1.0
9.78
2.07
u/ml
—
6
43
345
3115
1.17
1.50
4.6
3.6
41.37
49.50
ng/l
0.27
245
2214
15
79
1.91
1.50
1.0
1.1
—
—
—
0
0
20
116
1.74
1.49
1.4
1.5
—
—
—
0
0
16
87
1.85
1.46
2.1
1.7
—
—
—
0
0
9
38
2.38
1.46
1.1
1.3
—
—
—
0
0
36
246
1.48
1.42
1.2
1.2
—
—
—
0
0
18
103
1.76
1.41
1.2
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
10
47
2.14
1.34
1.5
1.2
—
—
—
0
0
6
24
2.51
1.30
1.0
1.0
1398.67
1761.67
miu/ml
—
6
24
5
18
2.79
1.28
1.6
1.8
1.17
1.23
mmol/l
—
5
18
16
267
0.59
1.27
2.6
1.7
—
—
—
0
0
8
35
2.30
1.27
1.1
1.6
1.20
7.27
nmol/l
—
8
26
8
37
2.17
1.21
1.0
1.2
—
—
—
0
0
10
50
2.01
1.16
1.1
1.0
—
—
—
0
0
13
222
0.58
1.15
1.2
1.4
—
—
—
0
0
44
327
1.36
1.14
3.3
3.4
789.20
4275.30
u/ml
0.57
38
282
12
65
1.86
1.13
2.2
2.2
666.50
649.88
ml
—
6
43
10
183
0.54
1.12
1.8
3.7
28.44
25.75
mg/l
—
10
118
7
31
2.27
1.10
1.0
1.5
—
—
—
0
0
7
31
2.27
1.10
1.7
1.1
—
—
—
0
0
51
391
1.32
1.09
1.3
1.3
—
—
—
0
0
5
21
2.39
1.09
1.0
1.2
—
—
—
0
0
5
21
2.39
1.09
1.6
1.1
—
—
—
0
0
5
21
2.39
1.09
1.6
1.1
—
—
—
0
0
13
74
1.77
1.07
1.2
1.1
—
—
—
0
0
9
46
1.97
1.03
1.0
1.1
—
—
—
0
0
5
22
2.28
1.03
1.2
1.2
—
—
—
0
0
9
48
1.88
1.00
1.1
1.4
—
—
—
0
0
24
164
1.48
1.00
1.7
2.1
8863.00
2912.67
u/l
—
7
62
16
100
1.61
0.97
2.0
1.5
65.78
58.13
%
—
9
68
13
77
1.70
0.95
2.3
1.8
—
—
—
0
0
21
303
0.69
0.93
3.5
4.1
1.30
1.36
mmol/l
0.19
21
295
10
55
1.83
0.92
2.2
1.2
—
—
—
0
0
10
55
1.83
0.92
1.4
1.3
134.11
172.75
pmol/l
—
10
55
10
55
1.83
0.92
2.2
1.2
—
—
—
0
0
6
29
2.08
0.89
1.0
1.1
105.13
211.66
iu/ml
—
6
29
31
230
1.36
0.85
2.1
1.4
—
—
—
0
0
158
1768
0.87
0.83
3.4
4.1
1.02
1.02
kg/l
0.22
33
245
6
34
1.77
0.76
1.0
1.0
—
—
—
0
0
13
197
0.66
0.76
1.2
1.5
—
—
—
0
0
18
255
0.70
0.75
3.9
4.1
3.84
3.89
mmol/l
0.14
18
250
9
58
1.56
0.70
1.8
1.1
—
43.40
—
0
5
12
77
1.57
0.68
1.4
2.6
—
—
—
0
0
9
59
1.53
0.68
1.8
1.2
—
61.88
—
0
8
26
198
1.32
0.64
1.3
1.2
—
—
—
0
0
5
29
1.73
0.64
2.8
1.9
—
—
—
0
0
5
29
1.73
0.64
2.8
1.9
—
—
—
0
0
5
30
1.67
0.61
2.8
1.9
—
—
—
0
0
0
20
0.00
0.60
0.0
7.2
—
73.07
—
0
15
124
1115
1.13
0.60
1.5
1.4
—
—
—
0
0
8
53
1.51
0.58
1.4
1.4
—
34.29
—
0
7
18
132
1.37
0.57
1.8
1.5
—
—
—
0
0
6
37
1.63
0.55
2.0
1.7
50.17
52.41
ug/l
—
6
37
6
96
0.62
0.52
1.5
1.6
—
—
—
0
0
11
75
1.47
0.51
1.5
1.2
—
—
—
0
0
10
67
1.50
0.49
1.8
1.5
—
—
—
0
0
7
45
1.56
0.49
1.0
1.1
353.43
539.36
u/l
—
7
39
27
217
1.25
0.48
3.2
2.3
265.20
100.16
ug/min
0.41
15
131
17
128
1.33
0.48
1.7
1.6
—
—
—
0
0
5
33
1.52
0.41
1.2
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
1.08
—
0
6
0
16
0.00
0.41
0.0
1.0
—
25.12
—
0
16
59
659
0.89
0.36
1.8
1.7
—
—
—
0
0
9
125
0.72
0.35
1.2
1.5
—
—
—
0
0
10
73
1.37
0.34
1.3
1.1
1.25
1.55
nmol/l
—
10
67
69
625
1.11
0.34
2.3
1.9
—
—
—
0
0
9
117
0.77
0.27
1.2
1.4
—
—
—
0
0
9
117
0.77
0.27
1.2
1.4
—
—
—
0
0
9
117
0.77
0.27
1.1
1.4
—
—
—
0
0
9
117
0.77
0.27
1.1
1.4
—
—
—
0
0
8
65
1.23
0.27
1.4
1.4
—
—
—
0
0
281
2718
1.05
0.25
4.3
5.0
2.09
2.52
ug/l
0.72
250
2424
74
688
1.08
0.24
2.4
2.0
—
—
—
0
0
5
38
1.32
0.23
2.8
1.7
—
—
—
0
0
5
38
1.32
0.23
2.8
1.7
—
—
—
0
0
26
228
1.14
0.23
1.3
1.4
—
—
—
0
0
23
200
1.15
0.22
1.8
1.6
24159.39
16273.19
e6/l
0.22
18
144
10
124
0.80
0.21
1.2
1.4
—
—
—
0
0
5
42
1.19
0.21
1.0
1.5
1.37
1.56
g/l
—
5
42
29
325
0.89
0.21
2.7
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.6
—
—
—
0
0
0
10
0.00
0.21
0.0
6.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
5
43
1.16
0.21
1.4
1.4
—
—
—
0
0
5
43
1.16
0.21
1.4
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
42
384
1.10
0.20
1.0
1.0
—
—
—
0
0
6
50
1.20
0.19
1.7
1.8
18.17
20.11
nmol/l
—
6
43
19
165
1.15
0.19
1.7
1.6
—
—
—
0
0
27
300
0.90
0.18
2.4
1.7
—
—
—
0
0
5
67
0.75
0.17
1.4
1.4
—
—
—
0
0
15
130
1.16
0.15
1.6
1.4
—
—
—
0
0
6
78
0.77
0.15
1.3
1.6
—
—
—
0
0
13
112
1.16
0.14
1.7
1.5
—
—
—
0
0
18
162
1.11
0.12
1.6
3.5
431.72
325.91
u/ml
0.09
18
153
69
720
0.96
0.11
2.2
2.4
7.24
6.89
ug/l
0.08
61
632
18
198
0.91
0.10
1.2
1.3
233.23
243.09
miu/ml
0.04
11
97
10
115
0.87
0.10
2.1
1.4
—
—
—
0
0
10
115
0.87
0.10
2.1
1.4
—
—
—
0
0
5
46
1.09
0.09
7.2
3.1
—
—
—
0
0
10
114
0.88
0.09
2.1
1.4
—
—
—
0
0
10
113
0.88
0.08
2.1
1.4
—
—
—
0
0
10
113
0.88
0.08
2.1
1.4
—
—
—
0
0
10
113
0.88
0.08
2.1
1.4
—
—
—
0
0
7
66
1.06
0.08
2.3
1.6
—
—
—
0
0
7
66
1.06
0.08
2.3
1.6
—
—
—
0
0
7
66
1.06
0.08
2.3
1.6
—
—
—
0
0
7
83
0.84
0.07
1.9
1.5
—
—
—
0
0
222
2190
1.02
0.07
3.6
4.3
24.07
21.26
%
1.39
92
1049
9
104
0.86
0.06
1.2
1.3
7.48
7.21
mmol/l
—
9
86
34
325
1.05
0.06
1.5
1.8
—
—
—
0
0
24
253
0.95
0.05
1.4
1.8
—
—
—
0
0
45
455
0.99
0.00
3.4
2.7
0.13
0.22
e6/l
0.64
45
441
0
5
0.00
-0.00
0.0
1.0
—
65.20
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
-0.00
1.8
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_BLOODNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_BLOODNAS | 2.238 [1.91, 2.63] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.245 |
During the follow-up period (1.1.1998 — 31.12.2019), 570 out of 2131 females with D3_BLOODNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_BLOODNAS | 2.256 [1.9, 2.67] | < 0.001 |
| Birth year | 0.981 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 665 out of 1883 males with D3_BLOODNAS died.
Mortality risk
Mortality risk for people of age
years, who have D3_BLOODNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.227% | 0.362% |
| 5 | 1.374% | 2.281% |
| 10 | 3.61% | 5.483% |
| 15 | 6.907% | 9.997% |
| 20 | 11.592% | 16.14% |
Relationships between endpoints
↥Index endpoint: D3_BLOODNAS – Other and unspecified diseases of blood and blood-forming organs
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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