hematologic disease: A disease involving the hematopoietic system.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2630 |
4. Check minimum number of eventsNone |
2630 |
5. Include endpoints |
2774 |
6. Filter based on genotype QC (FinnGen only) |
2706 |
Control definitions (FinnGen only)
- Control exclude
- D3_BLOODOTHER
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D70-D77
- Name in latin
- Alii morbi sanguinis et organorum haematopoeticorum
Similar endpoints
↥List of similar endpoints to
Other diseases of blood and blood-forming organs
based on the number of shared cases.
Similar with more cases:
- Other diseases of blood and blood-forming organs, wide
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 17063 | 8307 | 8588 |
| Only index persons | 14250 | 7111 | 7139 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.24 | 0.24 | 0.24 |
| Only index persons | 0.27 | 0.26 | 0.27 |
| Median age at first event (years) | |||
| Whole population | 60.51 | 61.34 | 59.66 |
| Only index persons | 59.31 | 60.14 | 58.49 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2706 | 1335 | 1371 |
| Unadjusted period prevalence (%) | 0.55 | 0.47 | 0.63 |
| Median age at first event (years) | 59.65 | 58.01 | 61.24 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2774
- Matched controls
- 27740
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
26.8
307.7
886
478
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
155.6
307.7
618
51
L01XX05
ATC
hydroxycarbamide; oral
103.7
307.7
740
97
D45
ICD-10 Finland
Polycythaemia vera
52.2
307.7
368
81
D75.1
ICD-10 Finland
Secondary polycythaemia
1202.3
307.7
839
10
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
1562.3
307.7
786
7
D75.2
ICD-10 Finland
Essential thrombocytosis
2481.8
307.7
966
6
XW000
NOMESCO Finland
Bone marrow biopsy
22.9
307.7
763
452
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
44.5
307.7
302
76
9962/3-C42.1
ICD-O-3
Essential thrombocythemia of bone marrow
232.9
307.7
254
12
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
89.3
274.1
144
17
TPH00
NOMESCO Finland
Phlebotomy
37.4
228.4
142
40
SPAT1074
SPAT
Venesection
42.0
225.6
136
34
D75.0
ICD-10 Finland
Familial erythrocytosis
1012.3
195.2
189
*
L03AB05
ATC
interferon alfa-2b; parenteral
49.3
187.7
109
23
D75.8
ICD-10 Finland
Other specified diseases of blood and blood-forming organs
763.0
148.6
145
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
147.6
613
2068
9950/3-C42.1
ICD-O-3
Polycythemia vera of bone marrow
38.7
146.4
90
24
L01XX35
ATC
anagrelide; oral
368.0
141.2
141
*
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
46.3
100.2
59
13
L03AB04
ATC
interferon alfa-2a; parenteral
52.9
99.5
57
11
B99
ICPC
Blood/lymph/spleen disease other
24.0
95.0
68
29
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.2
87.6
393
1362
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
14.6
86.3
78
55
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
13.8
83.7
78
58
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
70.7
1443
9673
M04AA01
ATC
allopurinol; systemic
2.5
66.7
494
2211
R71
ICD-10 Finland
Abnormality of red blood cells
22.2
65.0
48
22
9960/3-C42.1
ICD-O-3
Myeloproliferative neoplasm, NOS, of bone marrow
83.3
58.2
65
8
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
75.5
52.2
59
8
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
6.6
49.1
80
125
28900
ICD-8 Finland
Other disease of blood and blood-forming organs, Polycythaemia, secondary
+∞
48.1
46
*
212
Kela drug reimbursment
Gout
4.8
42.9
98
210
174
Kela drug reimbursment
Ruxolitinib
79.8
42.0
47
6
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
13.9
40.0
37
27
TPH00, ,
SPAT
74.6
39.0
44
6
374
Kela drug reimbursment
Ruxolitinib
87.4
38.9
43
5
28998
ICD-8 Finland
Other disease of blood and blood-forming organs, Alii definiti
+∞
38.6
37
*
L01EJ01
ATC
ruxolitinib; oral
85.3
37.9
42
5
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
11.3
37.1
39
35
WW500
NOMESCO Finland
Blood transfusion
3.3
36.4
142
447
Z2221
NOMESCO Finland
Medical doctor
1.8
36.2
770
4956
B01AB05
ATC
enoxaparin; parenteral
1.7
35.6
895
6032
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
10.1
34.5
39
39
28999
ICD-8 Finland
Other disease of blood and blood-forming organs, Other and unspecified
+∞
34.4
33
*
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.6
34.1
213
868
C03CA01
ATC
furosemide; systemic
1.7
34.1
864
5823
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
33.1
838
5636
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
4.6
31.6
75
166
ZXE00
NOMESCO Finland
One hour or less
1.6
30.6
1046
7561
B28
ICPC
Limited function/disability (B)
9.5
28.9
34
36
C07AB07
ATC
bisoprolol; oral
1.6
28.4
1354
10520
H02AB06
ATC
prednisolone; systemic
1.6
27.4
1278
9852
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
27.0
536
3345
N02AX02
ATC
tramadol; systemic, rectal
1.6
26.8
1171
8882
Z3231
NOMESCO Finland
Registered nurse
1.6
26.7
745
5086
R06.0
ICD-10 Finland
Dyspnoea
1.6
26.5
739
5044
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
26.3
482
2939
C03DA01
ATC
spironolactone; oral
1.9
26.0
353
1961
A02BC02
ATC
pantoprazole; systemic
1.6
25.7
1826
15342
D70.82
ICD-10 Finland
Drug-induced neutropenia
136.3
25.6
27
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
25.3
25.3
35
14
T90
ICPC
Diabetes non-insulin dependent
1.6
24.9
671
4530
G47.3
ICD-10 Finland
Sleep apnoea
1.6
24.5
640
4284
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
5.1
24.5
51
101
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
23.9
223
1080
Y28
ICPC
Limited function/disability (Y)
9.1
23.9
29
32
Z3226
NOMESCO Finland
Physiotherapist
1.7
23.8
502
3176
B01AA03
ATC
warfarin; systemic
1.7
23.6
537
3466
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
23.6
304
1656
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
23.5
1646
13650
SPAT1262
SPAT
Handing over of treatment supplies
1.7
23.5
492
3107
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
23.3
613
4104
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
23.2
392
2326
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
23.1
680
4678
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.2
23.1
192
888
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
22.2
638
4358
103
Kela drug reimbursment
Diabetes, insulin-treated
1.6
21.9
737
5219
L01XE18
ATC
[U] ruxolitinib
63.0
21.9
25
*
XX7BT
NOMESCO Finland
Radioactive phosphorus therapy
115.9
21.6
23
*
E29.1
ICD-10 Finland
Testicular hypofunction
4.4
21.6
54
125
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
21.2
660
4589
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.0
21.1
255
1358
R50.9
ICD-10 Finland
Fever, unspecified
1.7
21.0
391
2383
A10BA02
ATC
metformin; oral
1.5
21.0
772
5568
R4110
NOMESCO Finland
Physiotherapy
1.5
20.7
728
5197
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.1
20.5
216
1096
UJF30
NOMESCO Finland
Ileoscopy through colon
1.9
20.2
282
1574
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
20.2
433
2741
D75
ICD-10 Finland
Other diseases of blood and blood-forming organs
+∞
19.8
19
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
19.7
891
6693
B04
ICPC
Blood symptom/complaint
6.5
19.6
32
50
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.9
19.6
262
1443
J01DB01
ATC
cefalexin; oral
1.6
19.6
2179
19470
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
18.3
19.1
29
16
C08CA01
ATC
amlodipine; oral
1.5
19.1
1022
7925
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.6
18.9
112
444
J96.1
ICD-10 Finland
Chronic respiratory failure
3.2
18.8
76
245
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.1
18.8
175
847
S97
ICPC
Chronic ulcer skin
2.1
18.4
176
861
R03AC02
ATC
salbutamol; inhalant
1.4
18.3
1379
11357
D58.2
ICD-10 Finland
Other haemoglobinopathies
44.3
18.2
22
5
ZX120
NOMESCO Finland
Intravenous
1.9
17.9
250
1395
R03BB04
ATC
tiotropium bromide; inhalant
1.8
17.8
285
1659
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
20.2
17.7
26
13
B01AC14
ATC
[U] anagrelide
+∞
17.7
17
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
17.5
291
1712
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
17.4
266
1526
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
17.4
304
1817
N06AX11
ATC
mirtazapine; oral
1.5
17.2
852
6477
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
17.2
561
3920
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
13.3
16.9
29
22
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
16.8
435
2880
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
16.6
829
6303
L03AA04, ,
ATC
16.4
16.5
26
16
M79.6
ICD-10 Finland
Pain in limb
1.4
16.5
1042
8269
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
4.4
16.4
41
95
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
16.3
917
7124
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.2
16.1
140
659
WW200
NOMESCO Finland
Immunization
2.8
16.0
81
297
B74
ICPC
Malignant neoplasm blood other
18.6
16.0
24
13
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
15.8
298
1818
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
15.7
678
5005
B01AB04
ATC
dalteparin; parenteral
2.1
15.6
141
675
E66.8
ICD-10 Finland
Other obesity
2.2
15.5
139
663
J01MA12
ATC
levofloxacin; systemic
1.5
15.4
474
3260
C90.0
ICD-10 Finland
Multiple myeloma
3.9
15.3
45
118
E83.1
ICD-10 Finland
Disorders of iron metabolism
6.5
14.9
24
37
J01MA02
ATC
ciprofloxacin; systemic
1.4
14.8
989
7887
B03XA01
ATC
erythropoietin; parenteral
4.5
14.7
35
78
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
14.3
1051
8497
ZXD05
NOMESCO Finland
Urgent procedure
1.4
14.3
746
5689
C09AA05
ATC
ramipril; oral
1.4
14.3
649
4828
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
14.2
441
3034
B03XA02
ATC
darbepoetin alfa; parenteral
2.8
14.1
69
249
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.7
14.0
258
1561
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.6
14.0
413
2811
AA1AD
NOMESCO Finland
CT of head and brain
1.4
13.8
691
5227
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
13.8
289
1811
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
20.1
13.8
20
10
M10.9
ICD-10 Finland
Gout, unspecified
1.9
13.8
189
1049
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.7
13.7
284
1774
R04.0
ICD-10 Finland
Epistaxis
1.8
13.7
200
1132
N02BE01
ATC
paracetamol; systemic, rectal
1.5
13.6
2345
21725
A10AE04
ATC
insulin glargine; parenteral
1.7
13.6
251
1521
D73.5
ICD-10 Finland
Infarction of spleen
+∞
13.5
13
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
13.4
631
4718
L01EA01
ATC
imatinib; oral
25.9
13.4
18
7
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
13.2
322
2095
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
13.1
640
4813
189
Kela drug reimbursment
Imatinib
12.2
13.1
23
19
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.0
13.0
146
758
UJF32
NOMESCO Finland
Coloscopy
1.4
13.0
655
4954
R53
ICD-10 Finland
Malaise and fatigue
1.4
13.0
568
4186
C07AB02
ATC
metoprolol; systemic
1.5
12.9
507
3660
Z2446
NOMESCO Finland
Social worker
1.9
12.8
164
889
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
12.7
553
4071
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.7
12.6
222
1326
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
4.8
12.6
28
59
D72.1
ICD-10 Finland
Eosinophilia
70.2
12.6
14
*
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
3.3
12.6
47
145
WX402
NOMESCO Finland
General anaesthesia
1.5
12.6
507
3675
WX002
NOMESCO Finland
Sedation and analgesia
1.5
12.6
481
3451
H02AB09
ATC
hydrocortisone; systemic
2.7
12.6
67
253
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
12.6
1274
10761
2890X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Polycythaemia, secondary[ERYTHROCYTOSIS SECUNDARIA, NUD]
+∞
12.5
12
*
2898X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Other specified diseases of blood and blood-forming organs
+∞
12.5
12
*
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.9
12.5
169
934
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.6
12.5
267
1682
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
3.2
12.2
47
148
207
Kela drug reimbursment
Chronic arrhythmias
1.5
12.2
396
2748
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
2.7
12.1
65
247
205
Kela drug reimbursment
Chronic hypertension
1.4
12.1
686
5288
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.6
12.0
326
2173
R72
ICD-10 Finland
Abnormality of white blood cells, not elsewhere classified
11.1
12.0
22
20
B01AC04
ATC
clopidogrel; oral
1.5
11.9
418
2944
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.1
11.9
110
531
A46
ICD-10 Finland
Erysipelas
1.5
11.9
364
2491
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.7
11.9
201
1188
TFP20
NOMESCO Finland
Cardiodefibrillation
1.8
11.9
193
1128
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
11.8
701
5437
C08CA05
ATC
nifedipine; systemic
1.9
11.7
155
850
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
4.0
11.7
33
84
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
4.5
11.7
28
63
316
Kela drug reimbursment
Imatinib
30.1
11.6
15
5
I50.0
ICD-10 Finland
Congestive heart failure
1.8
11.6
186
1082
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.9
11.5
153
840
J01FF01
ATC
clindamycin; systemic
1.4
11.4
657
5066
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.3
11.4
85
377
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.1
11.4
112
555
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
11.4
327
2209
121
Kela drug reimbursment
Severe hypofunction of sexual glands
2.9
11.3
53
187
XF600
NOMESCO Finland
Bloodpressure measurement
1.8
11.2
157
878
R11
ICD-10 Finland
Nausea and vomiting
1.7
11.2
200
1201
D69.1
ICD-10 Finland
Qualitative platelet defects
20.1
11.1
16
8
R4190
NOMESCO Finland
Nutritional therapy
2.2
11.1
89
407
L04AD01
ATC
ciclosporin; systemic
2.9
11.1
52
184
E66.00
ICD-10 Finland
Metabolic syndrome
1.9
11.1
143
779
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
11.1
322
2180
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
13.9
11.0
18
13
C10AA01
ATC
simvastatin; oral
1.3
11.0
1061
8848
R80
ICD-10 Finland
Isolated proteinuria
4.2
10.8
28
67
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
10.7
924
7570
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.9
10.7
141
772
A10BH01
ATC
sitagliptin; oral
1.6
10.7
241
1537
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
10.7
449
3274
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
12.9
10.6
18
14
JN4BD
NOMESCO Finland
Extensive body CT
1.6
10.6
248
1595
JN3AD
NOMESCO Finland
Abdominal CT examination
1.6
10.6
273
1798
E66.01
ICD-10 Finland
Obesity due to excess calories
1.7
10.5
199
1213
J01CA04
ATC
amoxicillin; systemic
1.4
10.5
2060
18892
R51.80
ICD-10 Finland
Headache
1.5
10.5
343
2381
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.7
10.4
178
1055
2387X
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Other lymphatic and haematopoietic tissues[STATUS LYMPHO- ET MYELOPROLIFERATIVUS NUD]
+∞
10.4
10
*
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
5.4
10.4
20
37
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
10.2
170
1000
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
4.0
10.2
28
70
A10BK03
ATC
empagliflozin; oral
1.6
10.2
246
1595
315
Kela drug reimbursment
Clopidogrel
3.4
10.1
35
103
N07BA03
ATC
varenicline; oral
2.0
10.1
115
601
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
10.1
1751
15731
E0000UV, ,
ATC
1.3
10.0
970
8060
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.6
10.0
237
1529
127
Kela drug reimbursment
Transplant complication
3.1
9.9
41
135
3AC01, ,
NOMESCO Finland
3.6
9.9
32
90
N05CF02
ATC
zolpidem; oral
1.4
9.9
406
2944
C01AA05
ATC
digoxin; systemic
1.7
9.9
198
1226
N05BA04
ATC
oxazepam; oral
1.4
9.9
603
4683
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
9.8
1088
9200
C10AA05
ATC
atorvastatin; oral
1.3
9.8
1046
8803
D64.8
ICD-10 Finland
Other specified anaemias
2.8
9.8
49
180
S16
ICPC
Bruise/contusion
2.3
9.8
74
331
N05CF01
ATC
zopiclone; oral
1.3
9.7
782
6326
XG466
NOMESCO Finland
Sleep oxymetry
2.2
9.7
82
384
WX723
NOMESCO Finland
CPAP therapy
2.0
9.7
105
540
N03AX16
ATC
[U] pregabalin
1.4
9.7
559
4302
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
3.1
9.6
39
127
A10BK01
ATC
dapagliflozin; oral
1.7
9.6
172
1033
J01DA01
ATC
[U] cefalexin
1.3
9.6
1527
13518
XF402
NOMESCO Finland
ECG with work load test
1.6
9.6
260
1733
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
1.8
9.5
134
752
R42
ICD-10 Finland
Dizziness and giddiness
1.4
9.5
532
4074
M54.5
ICD-10 Finland
Low back pain
1.3
9.4
828
6777
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
1.9
9.4
118
638
L28
ICPC
Limited function/disability (L)
1.4
9.4
417
3067
2899X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Unspecified diseases of blood and blood-forming organs
+∞
9.4
9
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.0
9.4
104
539
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
5.2
9.4
19
37
A10BJ02
ATC
liraglutide; parenteral
2.2
9.3
73
331
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.7
9.3
153
897
A10BJ06
ATC
semaglutide; parenteral
1.9
9.2
122
671
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
9.2
437
3252
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.5
9.2
301
2088
TK800
NOMESCO Finland
Hemodialysis
2.5
9.1
57
234
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.8
9.1
147
858
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
9.1
420
3108
B01AB10
ATC
tinzaparin; parenteral
1.6
9.1
234
1541
L01XE01
ATC
[U] imatinib
11.5
9.1
16
14
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
9.0
911
7588
H02AB07
ATC
prednisone; oral
1.5
9.0
324
2289
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.7
9.0
150
885
WX892
NOMESCO Finland
Monitored bed care
1.6
8.9
188
1179
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.5
8.9
263
1787
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.6
8.8
186
1168
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
8.8
560
4368
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
8.8
429
3205
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.4
8.7
363
2638
101
Kela drug reimbursment
Anterior pituitary hypofunction
3.9
8.7
25
65
D68.8
ICD-10 Finland
Other specified coagulation defects
3.3
8.6
31
94
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
2.7
8.6
43
158
N06AX12
ATC
bupropion; oral
1.8
8.6
138
805
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
8.6
467
3553
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
16.3
8.5
13
8
D47.0
ICD-10 Finland
Histiocytic and mast cell tumours of uncertain and unknown behaviour
16.3
8.5
13
8
201
Kela drug reimbursment
Chronic cardiac insufficiency
1.8
8.5
127
725
C09CA01
ATC
losartan; oral
1.3
8.5
618
4913
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
2.6
8.5
48
188
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
1.8
8.5
115
638
SPAT1260
SPAT
Consultation of another employee
1.4
8.5
397
2945
L14
ICPC
Leg/thigh symptom/complaint
1.6
8.4
182
1149
WX780
NOMESCO Finland
Remote monitoring CPAP
1.9
8.4
106
575
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
2.1
8.3
76
367
R02
ICPC
Shortness of breath/dyspnoea
1.5
8.3
297
2094
Q21.81
ICD-10 Finland
Eisenmenger's syndrome
+∞
8.3
8
*
D73.0
ICD-10 Finland
Hyposplenism
+∞
8.3
8
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
1.8
8.3
117
656
D07AC01
ATC
betamethasone; topical
1.3
8.3
849
7071
J01FA10
ATC
azithromycin; systemic
1.3
8.2
1328
11684
ZXA10
NOMESCO Finland
Bilateral
1.4
8.2
423
3186
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
8.2
438
3318
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
1.9
8.2
93
486
P01AB01
ATC
metronidazole; oral, rectal
1.3
8.2
911
7661
SPAT1263
SPAT
Sampling
1.3
8.2
969
8215
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
4.4
8.1
20
46
TKC20
NOMESCO Finland
Catheterisation of bladder
1.7
8.1
163
1010
N06AX16
ATC
venlafaxine; oral
1.5
8.1
309
2206
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
8.1
1032
8823
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
17.2
8.1
12
7
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
8.0
732
6002
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
1.8
8.0
107
592
A10AB05
ATC
insulin aspart; parenteral
1.6
7.9
177
1127
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
7.9
367
2717
S18
ICPC
Laceration/cut
1.3
7.9
1097
9470
Z01.9
ICD-10 Finland
Special examination, unspecified
1.7
7.9
135
803
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
7.8
7.9
17
22
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
7.8
599
4791
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
1.7
7.8
143
866
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
7.7
447
3429
C02AC05
ATC
moxonidine; oral
1.8
7.7
116
664
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
7.7
223
1506
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
4.2
7.7
20
48
I50.1
ICD-10 Finland
Left ventricular failure
1.8
7.7
118
679
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
1.9
7.7
91
483
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
2.0
7.7
75
372
K92.1
ICD-10 Finland
Melaena
1.7
7.7
126
740
N30.0
ICD-10 Finland
Acute cystitis
1.4
7.7
335
2454
A41.9
ICD-10 Finland
Sepsis, unspecified
2.0
7.7
83
428
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
7.6
681
5559
Z71.8
ICD-10 Finland
Other specified counselling
1.3
7.6
672
5477
K99
ICPC
Cardiovascular disease other
2.1
7.6
68
327
D69.4
ICD-10 Finland
Other primary thrombocytopenia
25.1
7.6
10
*
SPAT1377
SPAT
Polysomnography
2.0
7.5
79
403
H02AB04
ATC
methylprednisolone; systemic
1.4
7.5
323
2359
SPAT1281
SPAT
Other administrative function
1.6
7.5
172
1103
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
2.3
7.5
55
244
I50
ICD-10 Finland
Heart failure
2.0
7.5
72
356
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
7.4
821
6884
L01AB01
ATC
busulfan; systemic
80.3
7.4
8
*
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
1.8
7.4
108
614
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.5
7.4
206
1382
A04AA01
ATC
ondansetron; systemic, rectal
1.6
7.4
171
1100
J45.8
ICD-10 Finland
Mixed asthma
2.0
7.3
70
346
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
7.2
642
5232
S01GX01
ATC
cromoglicic acid; ophthalmic
1.4
7.2
417
3197
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
1.9
7.2
82
430
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.4
7.2
320
2349
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
7.2
662
5421
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
2.1
7.2
63
301
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
2.3
7.2
53
236
R89.8
ICD-10 Finland
Abnormal findings in specimens from other organs, systems and tissues, other abnormal findings
30.1
7.1
9
*
A02BC05
ATC
esomeprazole; systemic
1.3
7.1
957
8202
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.5
7.1
246
1724
M10
ICD-10 Finland
Gout
1.8
7.1
106
606
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.4
7.1
272
1944
R06AE07
ATC
cetirizine; oral
1.3
7.1
986
8483
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
1.7
7.1
115
674
ZY010
NOMESCO Finland
Hospital outpatient
1.8
7.1
104
592
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.1
7.0
63
303
ZXE20
NOMESCO Finland
More than three and less than five hours
1.4
7.0
311
2284
A91
ICPC
Abnormal result investigation NOS
1.7
7.0
117
692
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
7.0
1635
14881
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
7.0
313
2303
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
6.9
378
2873
Z2445
NOMESCO Finland
Psychologist
1.9
6.9
80
423
J96.9
ICD-10 Finland
Respiratory failure, unspecified
3.6
6.9
22
62
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.3
6.8
525
4197
E66.9
ICD-10 Finland
Obesity, unspecified
1.9
6.8
78
411
XW000, ,
SPAT
16.7
6.7
10
6
R20.2
ICD-10 Finland
Paraesthesia of skin
1.6
6.7
148
941
A07EA06
ATC
budesonide; oral, local oral
1.9
6.7
80
427
P06
ICPC
Sleep disturbance
1.4
6.7
249
1770
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.4
6.7
342
2571
K59.0
ICD-10 Finland
Constipation
1.7
6.7
121
732
R4120
NOMESCO Finland
Occupational therapy
1.6
6.7
147
935
E53.8
ICD-10 Finland
Deficiency of other specified B group vitamins
4.0
6.6
18
45
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.5
6.6
184
1234
C09CA06
ATC
candesartan; oral
1.3
6.6
539
4342
R5110, ,
SPAT
1.6
6.5
145
924
N02AA05
ATC
oxycodone; systemic
1.3
6.5
402
3111
Z01.7
ICD-10 Finland
Laboratory examination
1.4
6.5
318
2374
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
1.7
6.5
103
601
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
1.9
6.5
75
397
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.5
6.5
227
1597
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
2.2
6.5
49
221
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
2.5
6.4
39
159
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
1.9
6.4
76
405
Z72.0
ICD-10 Finland
Tobacco use
2.1
6.4
58
281
R52.9
ICD-10 Finland
Pain, unspecified
1.5
6.4
213
1483
Z3229
NOMESCO Finland
Other healthcare associate professional
1.5
6.4
187
1268
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
2.2
6.4
53
248
A02BC01
ATC
omeprazole; systemic
1.3
6.4
621
5113
B01AF02
ATC
apixaban; oral
1.4
6.4
287
2113
N05BA01
ATC
diazepam; systemic, rectal
1.4
6.4
287
2113
I48.4
ICD-10 Finland
Atypical atrial flutter
3.7
6.4
19
51
M01AG02
ATC
tolfenamic acid; oral, rectal
1.4
6.3
304
2261
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.3
6.3
429
3366
N05CD07
ATC
temazepam; oral
1.4
6.3
267
1944
C09AA02
ATC
enalapril; systemic
1.3
6.3
446
3520
-50
ICPC
Medication/prescr/renewal
1.8
6.3
94
539
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.2
6.3
50
230
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.0
6.3
64
324
C92.9
ICD-10 Finland
Myeloid leukaemia, unspecified
+∞
6.3
6
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
2.3
6.2
43
186
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.0
6.2
63
318
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.3
6.2
380
2936
B86
ICPC
OTHER HAEMATOLOGICAL ABNORMALITY
26.7
6.2
8
*
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
2.4
6.2
41
174
R01AD12
ATC
fluticasone furoate; nasal
1.3
6.2
665
5538
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.5
6.2
182
1236
SPAT1254
SPAT
Administration of medicine
1.4
6.2
318
2393
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
2.3
6.2
43
187
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
6.2
323
2437
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.6
6.2
151
985
N06AA09
ATC
amitriptyline; systemic
1.5
6.2
213
1494
K60
ICPC
Cardiovascular, Result test/procedure
3.2
6.1
23
72
J01AA02
ATC
doxycycline; systemic
1.2
6.1
1951
18214
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
12.5
6.1
10
8
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
6.1
451
3583
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.3
6.1
440
3484
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
6.0
491
3949
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.7
6.0
113
691
N06AX21
ATC
duloxetine; oral
1.4
6.0
249
1807
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1025
3044
4.75
320.94
2.8
2.6
24.94
22.90
%
3.68
914
2609
2122
10776
5.12
319.44
13.1
5.9
27.17
27.44
%
0.51
2032
10093
2157
11183
5.18
313.38
11.6
5.6
0.06
0.04
e9/l
32.92
1948
9644
2150
11156
5.12
310.98
11.7
5.6
0.65
0.59
e9/l
8.41
1943
9625
2086
10626
4.88
308.01
12.2
5.7
57.86
57.61
%
0.43
1987
9937
885
1871
6.48
307.65
3.6
2.5
79.55
70.04
e9/l
8.25
633
1416
1343
2506
9.45
307.65
7.1
3.9
260.53
244.77
u/l
2.24
1282
2366
815
225
50.88
307.65
1.1
1.1
—
—
—
0
0
551
331
20.52
307.65
1.5
1.5
—
—
—
0
0
834
344
34.24
307.65
1.4
1.2
28.37
44.72
u/l
0.98
737
295
2085
10166
5.23
307.65
12.7
5.8
0.85
0.67
%
29.36
1993
9464
2115
10501
5.27
307.65
13.4
6.1
8.82
8.69
%
0.80
2023
9805
2108
10455
5.23
307.65
12.7
5.8
2.76
2.84
%
0.92
2016
9749
1068
2523
6.26
307.65
3.3
2.5
1.85
1.80
%
0.76
939
2222
2157
10484
5.75
307.65
13.9
6.1
—
—
—
0
0
1042
3247
4.54
304.30
2.6
2.5
2.42
2.31
g/l
8.48
975
3007
2183
11591
5.15
302.61
12.6
5.8
0.22
0.19
e9/l
3.36
1995
10125
2166
11479
5.05
299.73
11.8
5.7
2.11
1.91
e9/l
1.72
2004
10128
1057
3522
4.23
278.38
2.8
2.5
14.66
13.06
umol/l
7.84
997
3288
2236
13036
4.69
248.80
17.1
8.5
4.68
4.15
e9/l
8.19
2030
11347
1309
6061
3.20
193.20
3.8
2.6
2309.24
5493.39
umol/l
2.80
1183
5293
589
1697
4.14
181.61
7.3
3.7
0.94
0.62
%
2.11
254
532
585
1767
3.93
167.86
7.4
4.0
0.14
0.10
%
0.74
235
539
1718
9917
2.92
160.42
17.9
9.4
0.02
0.00
e9/l
3.70
1466
8097
1883
11869
2.83
140.57
9.0
6.1
12.24
11.59
umol/l
1.41
1829
11273
1590
9278
2.67
137.36
4.0
2.8
151.77
135.13
ug/l
0.91
1463
8531
300
643
5.11
132.88
3.0
2.5
3.25
3.63
g/l
4.32
289
606
230
443
5.57
114.56
4.3
3.7
59.18
58.09
%
0.55
230
443
218
430
5.42
105.63
3.6
3.5
4.63
4.23
e9/l
1.11
218
430
352
1017
3.82
105.02
2.4
1.8
1.20
1.54
g/l
8.24
301
875
2301
17583
2.81
93.55
13.0
7.4
81.69
78.23
u/l
3.07
2218
16555
1031
5688
2.29
89.73
2.8
2.2
3.96
2.97
mg/l
9.09
878
4816
52
11
48.16
88.96
2.4
4.8
—
—
—
0
0
238
600
4.25
85.29
3.2
3.2
1.36
1.58
mg/l
3.65
221
546
262
711
3.96
84.92
4.3
3.7
45.55
65.81
mg/l
1.00
228
572
1558
10301
2.17
84.68
8.1
6.0
1.22
1.21
mmol/l
3.25
1431
9356
1664
11311
2.18
83.90
8.7
6.8
1.21
1.21
mmol/l
0.51
1351
9609
261
713
3.94
83.78
4.3
3.7
52.36
78.92
mg/l
0.60
228
577
255
691
3.96
82.77
4.2
3.7
5.49
2.50
ratio
0.33
19
58
468
1855
2.83
81.82
3.4
2.8
66.85
66.35
g/l
0.67
422
1703
265
745
3.83
81.61
4.3
2.5
1.74
1.08
g/l
1.33
237
653
245
660
3.97
80.12
4.4
2.4
0.04
0.02
g/l
0.36
226
611
48
12
40.69
78.94
1.1
1.0
—
—
—
0
0
275
817
3.63
77.99
4.1
2.5
2.99
2.95
g/l
0.29
252
742
232
617
4.01
77.18
4.2
2.4
0.00
0.00
g/l
-0.00
213
571
248
697
3.81
76.29
2.8
2.1
92.39
91.12
%
0.38
223
677
243
683
3.80
74.71
4.1
2.3
38.43
37.77
g/l
0.93
221
607
418
1635
2.83
74.50
2.8
2.7
10.53
10.72
g/l
0.25
377
1485
1479
9890
2.06
74.29
6.2
4.8
35.48
35.48
g/l
0.00
1375
9205
227
611
3.96
74.21
4.3
2.4
0.00
0.00
g/l
-0.00
213
570
280
873
3.46
73.63
4.1
2.5
3.62
3.65
g/l
0.12
258
798
280
874
3.45
73.49
4.1
2.5
—
—
—
0
0
280
874
3.45
73.49
4.1
2.5
6.94
7.34
g/l
3.50
258
798
353
1283
3.01
71.82
2.0
1.8
1.52
1.37
g/l
0.41
320
1175
554
2553
2.46
70.52
4.2
2.7
7.80
8.29
umol/l
0.25
488
2244
263
817
3.45
69.45
4.0
2.5
10.62
10.23
g/l
0.58
240
738
987
5836
2.07
67.87
6.1
3.9
85.78
89.13
%
3.52
944
5696
197
511
4.07
67.68
1.6
1.5
—
—
—
0
0
594
3029
2.22
58.73
6.3
5.9
1.05
1.04
mmol/l
0.60
563
2807
2099
16691
2.06
56.75
5.1
4.0
12.38
12.26
mm/h
0.11
1955
15415
1786
13444
1.92
56.68
6.9
4.8
6.77
6.77
mmol/l
0.01
1724
12636
1349
9370
1.86
54.16
2.4
2.0
92.76
94.98
pmol/l
0.97
796
4843
1059
6871
1.88
52.31
3.8
3.3
82.02
81.70
e6/l
0.00
829
5316
203
648
3.30
51.01
3.1
2.4
184.98
190.61
%
0.34
194
615
985
6287
1.88
50.89
3.7
3.2
0.56
0.43
e6/l
0.68
768
4809
858
5271
1.91
49.66
1.8
1.5
20.48
20.45
nmol/l
0.02
759
4480
47
38
12.56
47.87
1.0
1.4
—
—
—
0
0
1478
10809
1.79
47.79
20.3
15.6
1.30
1.28
inr
0.32
545
3145
71
105
6.91
45.86
1.6
1.5
—
—
—
0
0
71
105
6.91
45.86
1.6
1.5
—
—
—
0
0
133
349
3.95
44.81
6.1
3.2
1.37
1.38
%
0.01
111
311
39
26
15.20
44.28
1.1
1.2
—
—
—
0
0
387
1848
2.27
43.88
4.0
3.8
1.22
1.23
mmol/l
0.38
338
1604
1151
7966
1.76
43.78
4.6
3.7
110.74
108.11
e6/l
0.03
855
5705
1071
7382
1.73
40.45
4.2
3.1
34.61
36.63
u/l
0.34
1032
7006
764
4809
1.81
39.28
3.1
2.6
4.37
5.18
e6/l
1.61
686
4326
781
4976
1.79
38.41
2.2
1.8
1.20
1.20
mg/l
0.00
604
3791
603
3550
1.89
38.28
3.0
2.1
31.22
29.84
s
5.43
578
3447
625
3723
1.88
38.25
4.2
3.2
0.82
0.82
mmol/l
0.09
597
3497
689
4284
1.81
36.48
1.9
1.8
1139.46
1168.02
nmol/l
0.33
508
3227
656
4094
1.79
33.97
1.8
1.5
2.46
2.49
g/l
0.12
435
2489
153
533
2.98
33.02
5.6
4.5
2.95
2.65
mmol/l
0.47
108
361
118
367
3.31
30.83
1.4
1.4
107.84
120.37
u/ml
0.39
19
74
950
6723
1.63
30.20
3.5
3.1
1727.46
1414.29
ng/l
1.23
785
5729
124
403
3.17
30.15
1.2
1.2
—
—
—
0
0
2500
22548
2.10
30.13
24.1
14.3
20.44
24.46
mg/l
9.46
2162
17889
2214
19369
1.71
27.43
32.7
16.9
15.71
14.98
%
7.34
2194
18985
416
2413
1.85
26.80
4.1
3.4
—
—
—
0
0
363
2028
1.91
26.25
2.6
2.1
357.84
369.96
nmol/l
0.60
342
1849
113
379
3.07
26.06
1.2
1.2
249.34
260.27
u/ml
0.15
70
236
958
6984
1.57
25.93
3.6
3.3
781.96
294.60
mg/l
1.60
629
4480
32
8
40.49
25.83
7.0
11.4
—
—
—
0
0
155
621
2.58
25.62
1.9
1.6
0.24
0.24
g/l
0.17
141
589
1388
11020
1.52
25.16
3.8
3.7
0.00
0.01
estimate
1.32
395
1962
995
7355
1.55
25.13
4.2
3.9
14.01
9.10
mg/mmol
1.78
612
4673
1374
10896
1.52
24.97
5.0
4.9
0.00
0.00
estimate
0.50
413
2041
140
542
2.67
24.79
1.6
1.4
8.18
9.20
u/l
0.48
108
446
130
485
2.76
24.73
3.4
2.4
18.06
16.16
%
3.14
72
245
367
2107
1.85
24.29
8.1
7.6
9.74
9.93
mmol/l
0.22
345
2008
156
646
2.50
24.06
1.8
1.5
1.22
1.18
g/l
0.91
143
612
1030
7726
1.53
24.06
3.5
3.3
2.35
2.35
mmol/l
0.86
907
6788
1370
10912
1.50
24.02
3.8
3.6
0.00
0.00
estimate
0.99
421
2167
567
3704
1.67
23.83
2.2
1.8
—
—
—
0
0
555
3618
1.67
23.48
3.4
3.0
2.31
2.10
e6/l
0.21
296
1964
118
430
2.82
23.47
5.6
5.0
785.38
726.75
iu/ml
0.03
13
56
2378
21467
1.75
23.29
24.6
13.4
78.88
80.06
ml/min/173m2
1.86
2102
17785
985
7363
1.52
23.16
3.7
3.2
7.78
7.60
mmol/l
0.54
793
6214
1175
9149
1.49
22.51
2.7
2.2
76.70
77.36
nmol/l
0.34
1049
8160
366
2149
1.81
22.43
2.5
2.4
33.61
60.90
u/l
0.67
323
1860
370
2191
1.79
22.02
2.5
2.2
0.22
0.21
g/l
0.25
337
2054
62
158
3.99
21.81
1.9
2.0
39.02
37.80
%
0.23
62
158
2532
23391
1.95
21.69
26.6
16.7
139.45
139.67
mmol/l
4.53
2485
22790
622
4252
1.60
21.51
3.4
3.1
2.46
2.45
mmol/l
0.28
532
3754
146
623
2.42
21.11
1.3
1.3
—
—
—
0
0
1730
14663
1.48
20.90
5.2
4.5
227.25
1784.82
e6/l
2.21
20
211
933
7012
1.50
20.84
2.3
2.1
186.28
227.86
u/l
0.80
862
6591
2533
23461
1.92
20.66
27.8
16.8
3.99
3.98
mmol/l
1.45
2479
22825
258
1391
1.94
20.58
3.7
3.5
2.46
1.82
mmol/l
1.78
185
1030
346
2054
1.78
20.34
8.5
7.4
1.43
1.36
mmol/l
0.44
341
2008
73
222
3.35
19.84
6.7
2.9
61.43
57.62
%
0.77
54
189
1948
16993
1.49
19.68
4.6
3.9
15.04
14.84
pmol/l
2.82
1745
15377
1733
14779
1.46
19.64
4.0
3.1
61.57
50.87
u/l
3.82
1624
13721
262
1467
1.87
18.59
3.9
3.6
5.30
5.16
kpa
1.66
245
1396
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
166
791
2.17
18.52
4.1
3.1
0.36
0.35
u/ml
0.12
99
441
53
136
3.95
18.50
1.2
1.2
—
—
—
0
0
2274
20589
1.58
18.49
5.6
4.7
1.94
2.14
mu/l
0.97
2077
18764
137
606
2.33
18.29
3.7
3.2
25.61
24.87
mmol/l
1.05
137
596
2305
20994
1.58
17.62
7.1
5.8
40.21
40.03
mmol/mol
0.35
2132
19380
555
3850
1.55
17.59
3.3
2.8
0.92
1.09
e6/l
0.51
302
2182
280
1631
1.80
17.45
1.9
1.6
—
—
—
0
0
417
2719
1.63
17.16
8.7
7.8
11.23
12.23
kpa
3.30
407
2586
304
1825
1.75
17.08
3.7
2.2
13.10
13.09
nmol/l
0.01
277
1632
397
2563
1.64
16.99
2.0
1.7
—
—
—
0
0
416
2719
1.62
16.94
8.8
7.8
5.21
5.11
kpa
1.01
407
2588
230
1277
1.87
16.73
3.0
3.4
4.45
4.45
pmol/l
0.01
191
1128
920
7128
1.43
16.68
2.9
2.6
52.68
71.62
u/l
1.03
839
6581
397
2581
1.63
16.50
2.1
1.7
—
—
—
0
0
625
4532
1.49
15.88
4.7
3.7
554.70
634.38
ng/l
0.07
506
3597
409
2709
1.60
15.70
8.9
7.8
1.07
1.08
mmol/l
0.02
339
2146
1089
8780
1.40
15.42
4.4
3.7
32.33
102.74
ng/l
0.77
818
6170
799
6107
1.43
15.34
1.7
1.7
1.58
1.39
mmol/l
5.44
630
5122
66
223
3.01
15.13
1.8
1.4
28.60
30.27
iu/ml
—
5
11
28
50
5.65
15.08
1.1
1.2
—
—
—
0
0
2337
21541
1.54
14.91
4.9
4.0
1.46
1.31
mmol/l
14.36
2152
19635
2557
24098
1.78
14.86
19.0
10.3
29.17
26.90
u/l
3.88
2484
23221
67
236
2.88
14.29
1.6
1.6
—
—
—
0
0
762
5893
1.40
13.35
4.1
4.0
0.00
0.00
estimate
1.28
388
1957
2394
22305
1.54
13.23
5.4
4.4
1.29
1.45
mmol/l
66.70
2221
20492
139
705
2.02
13.20
2.2
1.8
35.32
39.15
nmol/l
1.23
133
676
117
556
2.15
13.20
2.0
2.0
15.49
11.83
mg/l
1.07
105
508
45
132
3.45
13.03
1.8
2.0
—
—
—
0
0
362
2437
1.56
12.82
9.4
8.3
94.22
95.65
%
3.44
355
2343
103
471
2.23
12.79
1.5
1.5
—
—
—
0
0
36
92
3.95
12.71
1.6
7.9
6673.07
62.77
mg/l
0.49
28
65
65
244
2.70
12.35
2.4
2.4
1.63
1.48
g/24h
0.13
33
123
2402
22466
1.52
12.28
5.4
4.5
4.32
4.63
mmol/l
43.43
2253
20760
103
480
2.19
12.22
1.6
1.3
—
—
—
0
0
103
480
2.19
12.22
1.6
1.3
—
—
—
0
0
2438
22896
1.54
12.00
6.0
5.0
2.55
2.74
mmol/l
20.97
2269
21041
79
332
2.42
11.92
1.2
1.1
—
—
—
0
0
43
130
3.34
11.91
2.0
2.3
631.79
568.85
e6/l
0.22
33
112
321
2138
1.57
11.88
4.8
3.6
5.80
5.85
kpa
0.39
309
2071
50
167
3.03
11.76
1.1
1.3
194.00
193.64
titre
—
10
33
318
2127
1.56
11.54
4.9
3.6
1.63
1.99
mmol/l
0.86
266
1772
81
350
2.35
11.51
1.4
1.2
2.10
3.93
u/ml
0.90
31
121
11
0
+∞
11.46
1.2
0.0
—
—
—
0
0
41
124
3.34
11.36
2.0
2.3
0.25
0.22
e9/l
0.16
32
111
27
61
4.46
11.19
1.0
1.1
—
—
—
0
0
67
269
2.53
11.16
1.3
1.4
340.36
313.08
pmol/l
0.23
58
233
1014
8385
1.33
11.16
3.9
3.8
—
—
—
0
0
223
1380
1.67
11.14
1.9
1.6
—
—
—
0
0
125
650
1.97
11.10
1.8
1.7
—
—
—
0
0
80
350
2.32
11.06
1.3
1.2
—
—
—
0
0
706
5551
1.36
10.80
4.1
2.3
—
—
—
0
0
35
99
3.57
10.74
28.8
27.1
119.60
120.39
ug/l
0.02
30
81
83
374
2.26
10.72
1.9
1.6
—
—
—
0
0
164
942
1.79
10.70
1.7
1.8
40.58
38.42
u/l
0.66
138
833
103
508
2.07
10.61
1.9
1.5
—
—
—
0
0
1240
10598
1.31
10.60
4.0
2.6
—
—
—
0
0
57
218
2.65
10.50
2.1
2.2
—
—
—
0
0
77
340
2.30
10.44
1.4
1.2
5.38
5.08
u/ml
0.06
39
145
103
512
2.05
10.39
2.5
2.2
147.66
129.27
g/l
5.96
86
372
105
526
2.04
10.37
1.8
1.5
—
—
—
0
0
263
1729
1.58
10.28
4.4
3.9
93.20
91.95
ng/l
0.08
227
1496
144
809
1.82
10.12
2.9
2.3
562.35
502.85
ug/l
0.10
136
760
63
262
2.44
9.79
1.1
1.1
—
—
—
0
0
71
313
2.30
9.69
1.4
1.3
0.18
0.35
nmol/l
—
5
22
205
1289
1.64
9.63
12.0
11.0
—
—
—
0
0
323
2254
1.49
9.58
10.3
8.7
127.85
122.19
g/l
3.24
318
2185
26
65
4.03
9.50
1.2
1.1
68.75
92.67
%
2.23
16
36
234
1526
1.58
9.46
11.6
9.7
92.29
93.92
%
2.67
234
1518
71
319
2.26
9.28
1.2
1.1
110.64
115.39
%
0.54
61
295
115
624
1.88
9.05
1.9
1.6
269.84
285.44
mu/l
0.35
107
570
288
1987
1.50
9.02
3.0
3.0
234.87
202.33
ng/l
0.70
262
1806
2337
22019
1.39
8.89
5.3
4.6
6.12
5.99
mmol/l
4.38
2105
20003
25
64
3.93
8.86
1.2
1.4
77.25
89.58
%
0.59
16
36
16
15
10.72
8.78
1.5
1.4
—
—
—
0
0
119
660
1.84
8.76
1.9
1.7
—
—
—
0
0
132
759
1.78
8.63
1.6
1.4
19.55
28.54
iu/l
3.55
114
646
66
303
2.21
8.23
1.6
1.5
—
—
—
0
0
365
2694
1.41
8.00
1.8
1.8
1.53
1.49
%
0.58
307
2372
135
808
1.71
7.70
1.2
1.2
0.20
1.20
u/ml
—
6
63
56
248
2.28
7.64
1.2
1.1
91.86
96.55
%
0.58
50
235
42
164
2.58
7.51
1.5
1.9
17.73
18.14
nmol/l
0.10
42
150
113
648
1.78
7.50
1.3
1.2
—
—
—
0
0
53
232
2.31
7.43
2.6
2.3
—
—
—
0
0
114
660
1.76
7.33
1.5
1.4
295.18
282.94
ug/g
0.23
65
387
18
42
4.31
7.21
1.2
1.2
77.00
82.80
%
0.29
11
15
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
18
42
4.31
7.21
1.2
1.2
78.82
81.14
%
0.08
11
14
67
327
2.07
7.21
1.1
1.1
1.52
1.51
g/l
0.01
59
290
36
133
2.73
7.18
1.5
1.2
—
—
—
0
0
15
19
7.93
7.10
1.1
1.0
—
—
—
0
0
15
19
7.93
7.10
1.4
1.6
—
—
—
0
0
35
130
2.71
6.92
1.7
1.6
3.52
6.78
u/l
1.19
29
112
39
154
2.55
6.85
1.3
1.1
—
—
—
0
0
39
154
2.55
6.85
1.3
1.1
—
—
—
0
0
35
131
2.69
6.83
1.2
1.1
—
—
—
0
0
343
2582
1.37
6.66
2.4
2.3
148.61
149.18
ug/g
0.01
275
2080
578
4693
1.29
6.65
1.3
1.2
1.68
1.57
u/ml
0.09
132
1229
39
157
2.51
6.60
1.3
1.1
—
—
—
0
0
39
157
2.51
6.60
1.3
1.1
—
—
—
0
0
39
157
2.51
6.60
1.3
1.1
—
—
—
0
0
61
301
2.05
6.41
1.4
1.5
—
—
—
0
0
79
431
1.86
6.22
1.3
1.2
21.43
46.57
u/ml
—
7
44
598
4923
1.27
6.12
1.7
1.7
41037191.46
26598520.80
pmol/l
0.25
463
4083
69
365
1.91
5.98
1.9
1.5
—
—
—
0
0
69
365
1.91
5.98
1.9
1.5
—
—
—
0
0
17
44
3.88
5.98
2.8
2.8
14.79
14.73
ml/dl
0.02
17
39
242
1751
1.42
5.93
3.8
2.9
5.15
4.57
kpa
2.84
230
1693
12
15
8.03
5.83
1.0
1.0
—
—
—
0
0
71
385
1.87
5.73
2.1
2.0
4.92
5.23
mmol/24h
0.29
65
330
2581
25047
1.44
5.56
40.1
21.1
42.10
40.45
%
10.65
2456
23411
93
553
1.71
5.53
1.4
1.2
5.13
7.88
u/ml
—
9
89
2582
25063
1.44
5.50
39.7
21.0
329.80
247.64
e9/l
121.81
2539
24399
2582
25076
1.43
5.35
39.7
21.0
4.65
4.50
e12/l
14.84
2531
24333
2582
25077
1.43
5.34
39.7
21.0
7.98
6.70
e9/l
23.77
2534
24327
91
545
1.69
5.28
1.4
1.2
37.53
3.15
u/ml
—
9
50
2582
25083
1.42
5.27
40.0
21.1
140.15
135.94
g/l
18.80
2555
24691
78
448
1.76
5.25
1.3
1.1
—
10.98
—
0
5
69
384
1.82
5.16
1.5
1.5
—
—
—
0
0
24
89
2.71
4.84
1.1
1.2
—
—
—
0
0
37
169
2.21
4.81
1.6
1.5
—
—
—
0
0
48
243
1.99
4.79
3.3
3.7
—
—
—
0
0
84
507
1.68
4.77
4.6
2.8
36.01
36.81
umol/l
0.09
78
458
133
897
1.51
4.74
3.8
3.8
24.80
24.87
mmol/l
0.11
115
838
455
3731
1.26
4.73
1.3
1.3
31.85
35.44
iu/ml
0.18
141
1209
29
120
2.43
4.71
1.2
1.2
1.10
1.05
ratio
0.97
12
46
39
184
2.14
4.69
2.5
2.1
613.72
609.44
ml
0.02
25
117
31
133
2.35
4.66
1.5
2.9
35.95
43.52
%
—
8
77
48
248
1.95
4.54
1.5
1.5
0.31
0.30
nmol/l
0.02
36
191
49
255
1.94
4.54
1.6
1.5
—
—
—
0
0
49
255
1.94
4.54
1.6
1.5
—
—
—
0
0
29
124
2.35
4.41
1.4
1.4
1.85
1.24
nmol/l
1.27
22
96
102
661
1.56
4.38
1.8
1.8
—
—
—
0
0
64
368
1.76
4.35
1.3
1.1
—
—
—
0
0
40
197
2.05
4.33
1.2
1.2
—
—
—
0
0
105
688
1.55
4.30
1.5
1.6
0.41
9.67
iu/ml
0.48
26
126
53
290
1.84
4.25
1.3
1.4
—
—
—
0
0
113
755
1.52
4.24
2.2
2.8
—
—
—
0
0
12
25
4.82
4.18
1.8
2.5
—
—
—
0
0
24
97
2.49
4.13
2.8
3.7
—
—
—
0
0
18
63
2.87
4.06
1.7
1.2
20.33
15.90
%
—
6
10
181
1334
1.38
4.05
1.4
1.3
209.73
218.19
u/ml
0.05
167
1234
182
1352
1.37
3.90
1.3
1.2
126.66
145.50
iu/ml
0.23
56
506
298
2376
1.28
3.90
3.3
4.1
3.83
16.11
ug/l
2.95
241
1952
35
173
2.04
3.79
1.2
1.3
—
—
—
0
0
82
524
1.58
3.79
1.5
1.9
2.61
4.73
iu/l
2.93
24
180
1455
13508
1.16
3.76
3.0
2.8
—
—
—
0
0
27
121
2.24
3.73
1.4
1.5
—
—
—
0
0
29
135
2.16
3.67
1.1
1.0
—
—
—
0
0
24
103
2.34
3.66
1.5
1.2
70.00
70.00
%
—
6
15
424
3556
1.23
3.58
1.2
1.2
14.32
11.17
u/ml
0.36
142
1382
78
501
1.57
3.55
1.5
1.4
708.06
1740.14
e6/l
0.60
69
403
78
501
1.57
3.55
1.4
1.4
14.31
31.82
e6/l
0.69
67
383
230
2910
0.77
3.50
8.6
7.0
—
—
—
0
0
31
152
2.05
3.46
1.5
1.4
13.06
13.64
u/l
0.20
31
144
11
27
4.09
3.39
1.4
1.5
—
—
—
0
0
26
121
2.16
3.32
1.4
1.5
—
—
—
0
0
39
211
1.86
3.31
1.1
1.1
—
—
—
0
0
84
559
1.52
3.29
1.2
1.1
—
—
—
0
0
6
7
8.59
3.26
1.3
2.0
—
—
—
0
0
74
480
1.56
3.25
3.5
3.2
0.82
0.83
nmol/l
0.07
61
370
10
24
4.18
3.19
1.9
3.0
0.30
0.58
u/field
—
10
24
27
131
2.07
3.12
1.1
1.1
—
—
—
0
0
33
173
1.92
3.09
1.6
1.6
—
—
—
0
0
126
923
1.38
3.00
2.0
1.9
1.65
2.23
ug/l
0.27
109
814
5
5
10.01
2.98
1.2
1.0
—
—
—
0
0
5
5
10.01
2.98
1.2
1.4
—
—
—
0
0
23
107
2.16
2.96
5.6
3.7
—
—
—
0
0
84
573
1.48
2.96
1.4
1.3
—
—
—
0
0
36
198
1.83
2.93
1.0
1.0
306.63
285.38
mg/l
0.88
30
177
12
37
3.25
2.93
1.3
1.2
—
—
—
0
0
401
3420
1.20
2.86
1.5
1.4
—
—
—
0
0
28
144
1.95
2.80
1.4
1.4
—
—
—
0
0
6
10
6.01
2.70
1.2
1.6
1.53
1.36
%
—
6
10
49
303
1.63
2.68
1.4
1.4
—
—
—
0
0
40
241
1.67
2.44
1.3
1.3
278.52
280.54
mosm/kgh2o
0.17
31
176
17
76
2.24
2.44
1.5
1.6
—
—
—
0
0
39
234
1.68
2.42
1.1
1.1
—
—
—
0
0
39
234
1.68
2.42
2.3
1.4
—
—
—
0
0
33
190
1.75
2.37
1.7
1.4
161.65
164.31
pmol/l
0.03
33
190
83
593
1.41
2.36
2.6
2.2
139.09
117.07
ug/min
0.13
46
362
52
339
1.54
2.33
1.4
1.4
—
—
—
0
0
47
300
1.58
2.30
1.1
1.1
—
—
—
0
0
14
59
2.38
2.29
1.6
1.6
—
—
—
0
0
28
156
1.80
2.25
1.0
1.1
58.32
43.06
mg/l
0.50
17
126
113
860
1.33
2.19
2.6
3.4
363.96
4783.31
u/ml
0.76
95
732
111
846
1.33
2.14
1.1
1.1
—
1.56
—
0
11
11
42
2.63
2.14
1.3
1.2
—
—
—
0
0
166
1337
1.26
2.10
1.6
1.5
—
—
—
0
0
35
213
1.65
2.10
2.4
1.5
—
—
—
0
0
188
1538
1.24
2.08
2.4
2.4
22.56
22.52
au/ml
—
9
116
899
8317
1.12
2.07
4.5
4.8
2.79
3.34
ug/l
0.28
787
7444
19
96
1.99
2.05
1.4
3.1
66.87
118.25
umol/l
—
8
57
14
63
2.23
2.01
1.7
1.6
85.00
191.33
nmol/24h
0.52
14
63
19
97
1.97
2.00
1.2
1.3
158.58
170.75
mmol/24h
0.16
19
97
68
487
1.41
1.96
1.5
2.0
1.07
0.80
nmol/l
2.06
56
405
18
91
1.98
1.95
1.1
1.1
111.85
94.42
%
0.56
13
72
35
218
1.61
1.94
1.0
1.1
—
—
—
0
0
536
4824
1.14
1.94
3.0
3.0
0.67
0.74
ug/l
1.96
357
3177
11
45
2.45
1.93
2.7
1.9
1.17
1.19
mmol/l
0.32
11
45
45
299
1.51
1.90
1.3
1.5
29.83
31.89
g/l
0.53
38
269
14
65
2.16
1.88
2.4
2.3
—
—
—
0
0
25
145
1.73
1.81
1.1
1.1
—
—
—
0
0
221
1867
1.20
1.81
2.8
2.7
60.78
65.27
ml/min/173m2
1.15
127
756
7
23
3.05
1.80
1.1
1.1
—
—
—
0
0
155
1887
0.81
1.79
1.8
1.8
—
—
—
0
0
27
162
1.67
1.74
2.1
1.5
0.92
0.97
g/l
0.32
27
162
109
857
1.28
1.73
2.1
1.8
—
—
—
0
0
168
1390
1.22
1.71
1.3
1.3
33.75
56.42
au/ml
1.27
12
78
5
13
3.85
1.71
1.2
1.2
—
—
—
0
0
196
1647
1.20
1.71
2.0
1.9
—
—
—
0
0
177
1475
1.21
1.69
8.9
7.4
25.32
24.54
mmol/l
1.58
171
1392
20
111
1.81
1.68
1.5
1.4
6.20
4.21
%
—
5
24
25
149
1.68
1.66
1.6
1.7
—
—
—
0
0
118
943
1.26
1.65
2.4
1.9
—
—
—
0
0
88
677
1.31
1.65
1.1
1.1
—
—
—
0
0
44
301
1.47
1.65
1.1
1.1
—
—
—
0
0
16
83
1.93
1.64
3.1
1.5
—
—
—
0
0
16
83
1.93
1.64
3.1
1.5
—
—
—
0
0
20
112
1.79
1.64
2.7
1.4
—
—
—
0
0
20
112
1.79
1.64
2.7
1.4
—
—
—
0
0
37
246
1.51
1.60
1.3
1.4
182932.16
101789.83
e6/l
0.41
25
145
25
151
1.66
1.60
1.1
1.1
274.26
287.84
mg/l
0.14
19
128
38
556
0.68
1.59
1.2
1.5
—
—
—
0
0
14
70
2.01
1.59
1.6
1.6
0.29
3.02
%
1.90
14
61
7
26
2.70
1.58
1.0
1.4
—
—
—
0
0
33
215
1.54
1.56
1.2
1.5
—
—
—
0
0
16
85
1.89
1.55
3.1
1.4
—
—
—
0
0
8
33
2.43
1.53
2.3
2.2
12.07
17.86
umol/l
—
8
33
5
15
3.34
1.52
1.6
1.0
4.42
5.45
nmol/l
—
5
15
86
672
1.29
1.47
1.1
1.1
—
—
—
0
0
17
293
0.58
1.47
1.4
1.5
—
—
—
0
0
32
211
1.52
1.46
1.4
1.5
21.91
28.93
%
0.55
14
133
11
52
2.12
1.44
1.5
1.4
0.41
0.37
ug/l
—
5
32
60
447
1.35
1.44
1.6
1.6
—
—
—
0
0
16
278
0.57
1.43
1.4
1.4
—
—
—
0
0
16
278
0.57
1.43
1.3
1.4
—
—
—
0
0
34
495
0.68
1.42
1.4
1.5
—
—
—
0
0
16
277
0.58
1.41
1.3
1.4
—
—
—
0
0
16
277
0.58
1.41
1.3
1.4
—
—
—
0
0
211
1821
1.17
1.40
2.1
2.0
—
—
—
0
0
435
4783
0.89
1.40
3.9
4.1
1.02
1.02
kg/l
0.46
81
688
11
53
2.08
1.38
1.0
1.3
50.87
26.34
ug/l
—
6
26
21
334
0.63
1.34
1.2
1.5
—
—
—
0
0
42
299
1.41
1.33
1.2
1.1
11.64
2.16
u/ml
0.88
14
125
12
61
1.97
1.32
1.3
1.1
—
—
—
0
0
15
83
1.81
1.31
1.0
1.1
1490.87
1640.67
miu/ml
0.20
15
83
17
98
1.74
1.31
1.1
1.2
145.42
216.60
iu/ml
0.95
17
98
40
284
1.41
1.29
1.3
1.4
1761.77
1659.05
e6/l
0.06
31
201
8
34
2.36
1.29
3.5
5.8
—
—
—
0
0
8
34
2.36
1.29
1.5
1.5
82.20
132.18
ng/l
—
8
34
12
62
1.94
1.27
1.3
1.1
—
—
—
0
0
18
107
1.69
1.25
1.1
1.0
—
—
—
0
0
6
25
2.40
1.24
1.5
1.9
48.83
47.76
umol/l
—
6
25
13
70
1.86
1.24
1.4
1.1
—
—
—
0
0
22
139
1.59
1.23
1.7
1.2
—
—
—
0
0
128
1072
1.20
1.23
4.0
2.5
0.62
0.65
%
0.44
128
1066
16
93
1.72
1.21
1.1
1.2
—
—
—
0
0
70
551
1.28
1.18
1.2
1.2
193.85
227.87
miu/ml
0.34
29
239
114
949
1.21
1.17
5.2
5.7
2.19
1.62
%
2.60
108
875
24
158
1.52
1.14
1.7
1.9
5.65
6.97
umol/l
0.26
15
97
22
142
1.55
1.14
1.7
1.2
—
—
—
0
0
14
80
1.75
1.12
1.3
1.2
0.35
0.30
g/l
—
8
65
7
30
2.34
1.12
1.0
1.1
—
—
—
0
0
73
585
1.25
1.09
1.2
1.1
36.16
5.81
u/ml
—
5
65
7
32
2.19
1.08
1.0
1.1
—
—
—
0
0
64
802
0.79
1.06
1.9
1.7
4.59
4.14
mg/l
0.17
57
586
28
195
1.44
1.04
2.3
1.4
—
—
—
0
0
28
195
1.44
1.04
2.3
1.4
—
—
—
0
0
28
195
1.44
1.04
2.3
1.4
—
—
—
0
0
77
625
1.24
1.04
1.4
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
20
130
1.54
1.02
1.4
1.1
—
—
—
0
0
49
377
1.31
1.01
1.1
1.1
213.09
102.58
iu/ml
0.34
11
82
38
282
1.35
1.00
1.6
1.6
67.65
62.56
%
0.43
20
179
25
172
1.46
0.99
1.2
1.4
0.98
1.20
promille
0.28
16
131
24
165
1.46
0.96
1.6
1.2
0.47
0.91
u/ml
0.48
16
90
70
568
1.24
0.96
1.3
1.2
—
—
—
0
0
9
51
1.77
0.94
1.0
1.2
—
—
—
0
0
27
192
1.41
0.92
4.0
4.8
67.36
47.03
u/ml
—
9
56
21
142
1.48
0.92
1.1
1.5
2.32
2.61
ug/l
0.19
15
118
26
184
1.42
0.91
1.3
1.2
—
—
—
0
0
19
126
1.51
0.91
1.2
1.1
0.98
1.18
u/l
1.76
11
62
13
79
1.65
0.88
1.7
2.2
17.86
119.67
ug/l
0.50
13
69
15
95
1.58
0.87
1.5
1.3
—
—
—
0
0
15
95
1.58
0.87
1.5
1.3
—
—
—
0
0
162
1431
1.14
0.87
4.6
3.1
137.66
129.36
g/l
3.00
155
1389
6
31
1.94
0.84
1.5
1.7
5.17
7.06
%
—
6
16
6
31
1.94
0.84
1.0
1.0
—
—
—
0
0
45
354
1.28
0.83
1.2
1.1
1.66
2.23
u/ml
0.17
28
175
6
114
0.53
0.82
1.3
1.3
—
—
—
0
0
19
130
1.46
0.80
1.4
1.5
—
—
—
0
0
17
114
1.49
0.79
1.1
1.8
—
—
—
0
0
121
1057
1.15
0.78
1.2
1.3
—
—
—
0
0
698
6648
1.07
0.78
3.9
4.2
22.38
21.52
%
0.77
320
3190
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
23
166
1.39
0.75
1.4
1.1
—
3.89
—
0
9
7
38
1.84
0.73
1.3
1.3
—
—
—
0
0
18
126
1.43
0.70
1.1
1.1
—
—
—
0
0
18
126
1.43
0.70
2.6
1.8
—
—
—
0
0
11
69
1.60
0.68
1.1
1.1
—
—
—
0
0
11
69
1.60
0.68
1.1
1.1
—
—
—
0
0
18
127
1.42
0.68
2.6
2.0
38.17
166.27
ug/min
—
6
33
7
44
1.59
0.65
1.0
1.0
—
—
—
0
0
7
44
1.59
0.65
1.1
1.1
—
—
—
0
0
5
29
1.73
0.64
1.2
1.0
—
—
—
0
0
14
198
0.71
0.60
1.3
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.4
—
—
—
0
0
17
122
1.40
0.60
1.1
1.2
157.71
137.14
nmol/l
0.50
17
122
20
148
1.35
0.59
1.1
1.1
10.09
4.68
nmol/l
—
5
36
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
121
1083
1.12
0.59
1.0
1.0
—
—
—
0
0
10
64
1.56
0.58
1.1
1.2
—
—
—
0
0
8
55
1.46
0.56
1.0
1.1
—
—
—
0
0
17
124
1.37
0.55
1.5
1.3
—
—
—
0
0
15
108
1.39
0.53
2.2
2.5
—
—
—
0
0
9
62
1.45
0.53
1.1
1.1
—
—
—
0
0
61
704
0.86
0.52
2.2
1.8
—
—
—
0
0
17
126
1.35
0.51
1.5
1.3
—
—
—
0
0
63
550
1.15
0.47
1.6
1.6
17202.72
15085.66
e6/l
0.13
46
394
55
480
1.15
0.43
1.8
2.2
13137.45
3159.62
u/l
0.53
14
194
11
78
1.41
0.43
1.2
1.2
—
—
—
0
0
42
359
1.17
0.42
1.5
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
0.07
—
0
10
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
33
278
1.19
0.40
2.2
1.3
—
—
—
0
0
33
279
1.18
0.38
2.2
1.3
—
—
—
0
0
33
280
1.18
0.37
2.2
1.3
—
—
—
0
0
55
487
1.13
0.37
2.1
1.3
—
—
—
0
0
34
290
1.17
0.36
1.0
1.0
1.35
1.67
u/ml
0.10
22
140
218
2061
1.06
0.36
2.5
2.4
7.81
7.41
ug/l
0.09
181
1831
312
2981
1.05
0.36
1.4
1.4
—
—
—
0
0
9
71
1.27
0.36
1.2
2.1
—
—
—
0
0
55
488
1.13
0.36
2.3
3.6
204.86
827.31
u/ml
0.60
49
461
26
218
1.19
0.34
1.7
2.6
—
—
—
0
0
11
82
1.34
0.34
1.0
1.0
—
—
—
0
0
17
138
1.23
0.30
1.1
1.1
—
—
—
0
0
45
499
0.90
0.26
3.1
3.7
16.56
27.46
mg/l
2.96
31
307
31
274
1.13
0.24
2.2
1.3
—
—
—
0
0
31
274
1.13
0.24
2.2
1.3
—
—
—
0
0
11
88
1.25
0.22
1.6
1.8
—
—
—
0
0
11
88
1.25
0.22
1.3
1.1
—
—
—
0
0
31
276
1.12
0.22
2.2
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
2.55
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
22.86
—
0
5
0
12
0.00
0.21
0.0
5.1
—
—
—
0
0
33
298
1.11
0.19
1.9
1.6
—
—
—
0
0
21
238
0.88
0.18
1.5
1.5
—
—
—
0
0
22
194
1.14
0.18
1.6
1.5
—
—
—
0
0
7
60
1.17
0.17
1.6
1.6
—
—
—
0
0
7
62
1.13
0.17
1.0
1.1
—
—
—
0
0
14
120
1.17
0.16
16.1
11.3
0.57
0.63
mmol/l
0.42
14
112
76
722
1.05
0.15
6.3
4.2
3.88
3.89
mmol/l
0.08
76
715
15
171
0.88
0.14
1.4
1.5
—
—
—
0
0
13
112
1.16
0.14
2.5
1.3
12.80
26.61
umol/l
4.28
13
105
19
211
0.90
0.13
1.0
1.0
0.78
0.29
u/ml
—
8
64
67
639
1.05
0.12
1.7
1.4
—
—
—
0
0
281
2864
0.98
0.11
5.1
4.6
30.38
32.32
%
2.44
209
1921
30
279
1.08
0.11
2.5
2.3
13.00
22.48
mg/l
—
5
70
69
661
1.04
0.11
1.8
1.9
—
—
—
0
0
88
849
1.04
0.10
1.9
1.9
—
—
—
0
0
16
177
0.90
0.10
1.0
1.0
726.40
709.20
ng/l
—
10
109
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
16
176
0.91
0.09
1.0
1.0
43.55
44.30
ng/l
0.02
11
107
16
176
0.91
0.09
1.0
1.0
302.55
298.24
ng/l
0.02
11
111
6
58
1.03
0.08
1.0
1.1
—
—
—
0
0
7
64
1.09
0.08
1.0
1.2
—
—
—
0
0
7
66
1.06
0.08
1.1
1.3
8.45
9.00
ug/l
—
7
66
15
137
1.10
0.07
1.0
1.4
1.49
1.54
g/l
0.19
15
137
32
305
1.05
0.06
1.0
1.1
0.11
1.88
u/ml
2.14
14
124
33
316
1.04
0.05
1.1
1.1
3.23
5.99
u/ml
0.74
18
152
48
495
0.97
0.05
3.1
3.2
1.50
1.56
mmol/l
0.14
43
479
22
213
1.03
0.01
1.5
1.7
—
—
—
0
0
10
94
1.06
0.01
1.6
1.3
—
—
—
0
0
22
214
1.03
0.00
1.1
1.3
92175.24
103038.56
e6/l
0.05
17
145
17
166
1.02
0.00
1.8
1.5
85.29
85.28
umol/l
0.00
17
166
23
234
0.98
0.00
1.0
1.0
2.49
3.81
u/ml
0.32
12
91
5
56
0.89
-0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
86
0.93
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
8.0
—
74.80
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
-0.00
18.2
7.7
—
—
—
0
0
7
70
1.00
-0.00
3.4
3.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
70
1.00
-0.00
3.4
3.0
—
—
—
0
0
26
260
1.00
-0.00
1.0
1.0
2.16
2.69
u/ml
0.18
17
123
5
56
0.89
-0.00
1.0
1.1
8.28
10.90
u/ml
—
5
33
Mortality – FinRegistry
↥Association
Association between endpoint D3_OTHERBLOOD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_OTHERBLOOD | 1.985 [1.78, 2.22] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.293 |
During the follow-up period (1.1.1998 — 31.12.2019), 1658 out of 6103 females with D3_OTHERBLOOD died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_OTHERBLOOD | 1.825 [1.62, 2.05] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 1754 out of 6045 males with D3_OTHERBLOOD died.
Mortality risk
Mortality risk for people of age
years, who have D3_OTHERBLOOD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.216% | 0.396% |
| 5 | 1.289% | 2.196% |
| 10 | 3.139% | 5.364% |
| 15 | 5.656% | 9.533% |
| 20 | 10.057% | 16.307% |
Relationships between endpoints
↥Index endpoint: D3_OTHERBLOOD – Other diseases of blood and blood-forming organs
GWS hits: 8
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data