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Antenatal screening

Z21_ANTEN_SCREE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Z36
  • Cause of death: ICD-10 Z36

2 out of 7 registries used, show all original rules.

59960

4. Check minimum number of events

None

59960

5. Include endpoints

None

59960

6. Filter based on genotype QC (FinnGen only)

59960

Control definitions (FinnGen only)

Control exclude
Z21_PERSONS_ENCOUNTERI_HEALTH_SERVI_CIRCUMSTANC_RELATED_REPRODUCTION

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Z3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 59960 59960 -
Unadjusted period prevalence (%) 20.44 20.44 -
Median age at first event (years) 30.07 30.07 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2274
Matched controls
18645
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
554.1
323.0
524
10
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
322.6
323.0
607
21
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
4503599627370496.0
323.0
1818
*
W78
ICPC
Pregnancy
97.3
323.0
603
69
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
191.6
323.0
509
28
Z30.2
ICD-10 Finland
Sterilization
+∞
323.0
376
*
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
37.2
323.0
559
162
O80.0
ICD-10 Finland
Spontaneous vertex delivery
33.8
323.0
1370
800
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
188.0
323.0
398
21
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
1438.0
323.0
537
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
83.5
323.0
389
46
SPAT1197
SPAT
Extensive health check-up of expecting family
234.0
323.0
457
20
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
7681.7
323.0
676
*
Z37.0
ICD-10 Finland
Single live birth
+∞
323.0
330
*
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
8227.2
323.0
709
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2973.2
323.0
572
*
SPAT1380
SPAT
Postpartum check-up
646.4
323.0
393
6
SPAT1379
SPAT
Health check-up of pregnant person
130.0
323.0
535
44
Z32.1
ICD-10 Finland
Pregnancy confirmed
57.5
323.0
415
72
Z39.2
ICD-10 Finland
Routine postpartum follow-up
648.4
323.0
447
7
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
34.3
284.3
396
114
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
29.3
280.1
406
137
MA3AE
NOMESCO Finland
Combined first trimester screening
+∞
263.6
267
*
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
+∞
262.6
266
*
MAA00
NOMESCO Finland
Amniocentesis
220.5
259.5
283
12
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
153.5
236.6
265
16
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
550.3
229.4
241
*
WX307
NOMESCO Finland
Obstetric epidural analgesia
519.7
217.4
229
*
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
+∞
194.2
198
*
O82.0
ICD-10 Finland
Delivery by elective caesarean section
29.0
180.0
261
83
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
31.3
177.2
252
74
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
+∞
172.3
176
*
Z36.9
ICD-10 Finland
Antenatal screening, unspecified
+∞
171.3
175
*
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
37.6
170.4
232
56
XMA22
NOMESCO Finland
General examination of pregnant woman
145.5
159.4
180
11
Z31.5
ICD-10 Finland
Genetic counselling
708.6
153.4
161
*
MAX99
NOMESCO Finland
Assistance to normal delivery
282.3
146.7
159
5
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
343.2
146.2
157
*
OAA11
SPAT
NA
117.4
139.0
160
12
O99.80
ICD-10 Finland
The fear of childbirth
88.1
134.8
160
16
LGA21
NOMESCO Finland
Laparoscopic sterilisation by constriction of Fallopian tubes
104.8
133.1
155
13
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
61.1
128.5
160
23
O81.4
ICD-10 Finland
Vacuum extractor delivery
35.6
125.6
173
43
W90
ICPC
Uncompl labour/delivery livebirth
359.3
116.4
125
*
MAE00
NOMESCO Finland
Outlet vacuum delivery
42.2
116.0
154
32
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
26.6
112.3
166
55
O80.8
ICD-10 Finland
Other single spontaneous delivery
42.1
112.1
149
31
O32.1
ICD-10 Finland
Maternal care for breech presentation
35.5
111.9
154
38
O02.1
ICD-10 Finland
Missed abortion
11.4
107.7
219
173
O48
ICD-10 Finland
Prolonged pregnancy
81.2
101.8
122
13
O20.0
ICD-10 Finland
Threatened abortion
32.6
101.2
142
38
W85
ICPC
Gestational diabetes
295.5
96.0
104
*
W84
ICPC
Pregnancy high risk
221.1
93.6
103
*
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
12.0
93.1
184
136
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
45.0
87.8
115
22
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
+∞
87.4
90
*
OAA10
SPAT
NA
135.3
83.5
95
6
MA4AT
NOMESCO Finland
Chorion biopsy with ultrasound guidance
704.8
78.7
83
*
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
50.4
77.9
100
17
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
39.7
76.1
102
22
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
12.4
76.1
147
103
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
66.2
75.6
93
12
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
71.4
75.6
92
11
LGA10
NOMESCO Finland
Sterilisation by destruction or division of Fallopian tubes
77.7
75.6
91
10
V252A
ICD-9 Finland
Contraceptive management, Sterilisation
0.1
73.3
18
1906
XMA00
NOMESCO Finland
NA
90.4
71.9
85
8
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
+∞
71.8
74
*
Z35.5
ICD-10 Finland
Supervision of elderly primigravida
634.4
70.9
75
*
OAA12
SPAT
NA
634.4
70.9
75
*
Z36.8
ICD-10 Finland
Other antenatal screening
+∞
70.8
73
*
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
10.9
69.5
143
114
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
608.1
68.0
72
*
SPAT1189
SPAT
Other ultrasound examination during pregnancy
46.3
66.9
87
16
ZXD05
NOMESCO Finland
Urgent procedure
2.6
66.1
620
2364
Z34
ICD-10 Finland
Supervision of normal pregnancy
590.6
66.1
70
*
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
53.5
64.7
82
13
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
+∞
63.0
65
*
SPAT1373
SPAT
Combined screening in early pregnancy
191.4
61.3
68
*
W92
ICPC
Compl labour/ delivery livebirth
538.4
60.3
64
*
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
23.0
58.2
89
33
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
111.4
57.1
66
5
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
4.3
55.4
227
468
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
165.4
52.7
59
*
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
25.4
52.6
78
26
Z3232
NOMESCO Finland
Midwife
7.2
52.4
137
165
SPAT1200
SPAT
Guidance for breast-feeding and breast care
41.6
52.1
69
14
WX234
NOMESCO Finland
Paracervical blockade
15.1
50.5
89
50
W29
ICPC
Pregnancy symptom/complaint other
99.2
50.5
59
5
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
97.5
49.6
58
5
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
82.7
49.5
59
6
O60
ICD-10 Finland
Preterm labour and delivery
18.8
49.2
80
36
OAA70
SPAT
NA
222.8
48.2
53
*
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
222.8
48.2
53
*
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
222.8
48.2
53
*
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
+∞
47.4
49
*
Z39.1
ICD-10 Finland
Care and examination of lactating mother
+∞
46.4
48
*
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
34.8
45.2
62
15
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
8.0
45.1
109
116
O47.9
ICD-10 Finland
False labour, unspecified
109.0
45.0
52
*
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
400.3
44.8
48
*
MAA10
NOMESCO Finland
Biopsy of chorionic villus
+∞
44.5
46
*
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
57.6
44.0
55
8
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
13.1
44.0
82
53
LGA00
NOMESCO Finland
Sterilisation by ligature of Fallopian tubes
51.3
43.2
55
9
O72.0
ICD-10 Finland
Third-stage haemorrhage
26.5
43.1
63
20
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
49.4
41.4
53
9
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
33.6
40.6
56
14
G03DA04
ATC
progesterone; systemic, rectal, vaginal
3.4
40.0
210
534
Z35.7
ICD-10 Finland
Supervision of high-risk pregnancy due to social problems
+∞
39.6
41
*
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
19.6
39.5
63
27
LGA20
NOMESCO Finland
Sterilisation by constriction of Fallopian tubes
58.7
39.4
49
7
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
26.6
39.1
57
18
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
27.6
38.8
56
17
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
+∞
38.7
40
*
SPAT1195
SPAT
Antenatal classes
122.5
38.5
44
*
O41.0
ICD-10 Finland
Oligohydramnios
36.3
38.4
52
12
G03GA01
ATC
chorionic gonadotrophin; parenteral
5.1
37.8
129
219
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
175.3
37.7
42
*
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
+∞
37.7
39
*
TMA00
NOMESCO Finland
Episiotomy
+∞
37.7
39
*
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
28.3
37.7
54
16
1412
FHL
Laparoscopy and sterilization
0.1
37.3
18
1166
G03GA06
ATC
follitropin beta; parenteral
7.3
36.7
94
110
WX322
NOMESCO Finland
Combined spinal-epidural analgesia in obstetrics
+∞
35.8
37
*
O75.6
ICD-10 Finland
Delayed delivery after spontaneous or unspecified rupture of membranes
114.0
35.7
41
*
WYA40
NOMESCO Finland
Assessment of oral health and treatment needs for family expecting first child
87.7
35.6
42
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.9
35.1
730
3765
XLA10
NOMESCO Finland
NA
3.3
34.5
194
519
WX306
NOMESCO Finland
Lumbar epidural anesthesy
4.9
34.3
119
206
N97.9
ICD-10 Finland
Female infertility, unspecified
5.3
33.5
109
175
O23.5
ICD-10 Finland
Infections of the genital tract in pregnancy
297.9
33.3
36
*
H01CA02
ATC
nafarelin; nasal
5.0
33.2
114
195
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
26.8
33.1
48
15
W05
ICPC
Pregnancy vomiting/nausea
55.5
32.0
40
6
OAA41
SPAT
NA
14.2
31.4
56
33
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
145.6
31.1
35
*
Z36.2
ICD-10 Finland
Other antenatal screening based on amniocentesis
+∞
30.9
32
*
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
272.4
30.4
33
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
30.4
577
2855
R2110
NOMESCO Finland
Giving the first information
2.9
30.4
197
581
G03GB02
ATC
clomifene; oral
3.7
29.9
139
319
C07AG01
ATC
labetalol; systemic
7.4
29.6
74
84
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
137.2
29.2
33
*
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
9.0
29.2
65
61
O40
ICD-10 Finland
Polyhydramnios
72.8
29.1
35
*
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
27.0
29.1
42
13
8221
FHL
Sterilization of the laparotomy pathway
0.1
28.8
7
765
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
44.0
28.5
37
7
XMA20
NOMESCO Finland
Early examination of pregnancy
259.5
28.5
31
*
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
32.5
28.3
39
10
WX230
NOMESCO Finland
Plexus blockade of nervus pudendus
91.5
28.2
33
*
FM1QE
NOMESCO Finland
Extensive ultrasound of fetal heart
+∞
28.0
29
*
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
23.4
28.0
42
15
O21
ICD-10 Finland
Excessive vomiting in pregnancy
128.7
27.3
31
*
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
+∞
27.0
28
*
MAC96
NOMESCO Finland
Other induction or advancement of labour
124.5
26.4
30
*
Z35.6
ICD-10 Finland
Supervision of very young primigravida
+∞
26.1
27
*
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
20.8
25.8
40
16
LCH11
NOMESCO Finland
Pharmacologic abortion
4.9
25.8
90
157
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
30.0
25.7
36
10
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
+∞
25.1
26
*
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
12.3
24.9
47
32
OAB30
SPAT
NA
+∞
24.1
25
*
WZB00
SPAT
NA
0.4
24.1
84
1794
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
215.9
23.7
26
*
G03GA05
ATC
follitropin alfa; parenteral
6.3
23.7
66
88
ZXE00
NOMESCO Finland
One hour or less
1.6
23.1
775
4490
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
58.2
22.7
28
*
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
107.7
22.6
26
*
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
74.7
22.6
27
*
MAB20
NOMESCO Finland
Failed external version
74.7
22.6
27
*
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
46.4
21.9
28
5
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
21.7
777
4558
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
+∞
21.2
22
*
SPAT1391
SPAT
Counselling and guidance related to family situation
11.9
21.0
40
28
MAC02
NOMESCO Finland
Rupture of aminiotic membrane for advancement of labor
+∞
20.3
21
*
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
66.3
19.9
24
*
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
66.3
19.9
24
*
Z86.4
ICD-10 Finland
Personal history of psychoactive substance abuse
66.3
19.9
24
*
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
95.2
19.8
23
*
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.0
19.4
288
1281
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
18.4
19.4
31
14
W79
ICPC
Unwanted pregnancy
6.1
19.1
54
74
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
63.5
18.9
23
*
W01
ICPC
Question of pregnancy
6.7
18.6
49
61
O62.1
ICD-10 Finland
Secondary uterine inertia
17.8
18.6
30
14
LGA11
NOMESCO Finland
Laparoscopic sterilisation by destruction or division of Fallopian tubes
39.7
18.3
24
5
SPAT1381
SPAT
Extensive health check-up at 4 months of age
165.3
18.0
20
*
O44.1
ICD-10 Finland
Placenta praevia with haemorrhage
60.7
18.0
22
*
WZC00
SPAT
NA
0.3
17.4
37
992
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
+∞
17.4
18
*
MAB10
NOMESCO Finland
External version
+∞
17.4
18
*
ZYC02
SPAT
NA
0.3
17.4
27
850
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
14.6
17.4
30
17
Z30.0
ICD-10 Finland
General counselling and advice on contraception
2.2
17.2
184
712
O30.0
ICD-10 Finland
Twin pregnancy
9.7
17.2
36
31
O12.1
ICD-10 Finland
Gestational proteinuria
58.0
17.1
21
*
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
58.0
17.1
21
*
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
157.0
17.1
19
*
G02CB01
ATC
bromocriptine; systemic
3.6
16.9
78
180
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.8
16.8
355
1777
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
36.4
16.6
22
5
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.5
16.5
1297
8885
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
30.3
15.9
22
6
OAB42
SPAT
NA
0.4
15.9
53
1157
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.9
15.9
263
1214
O28.1
ICD-10 Finland
Abnormal biochemical finding on antenatal screening of mother
23.8
15.7
23
8
OAA48
SPAT
NA
+∞
15.4
16
*
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
140.3
15.2
17
*
O65.4
ICD-10 Finland
Obstructed labour due to fetopelvic disproportion, unspecified
33.0
14.8
20
5
R51.80
ICD-10 Finland
Headache
1.7
14.8
364
1905
G03GA04
ATC
urofollitropin; parenteral
4.0
14.7
60
125
MAA96
NOMESCO Finland
Other intrauterine operation on pregnant uterus or fetus
+∞
14.5
15
*
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
+∞
14.5
15
*
J01DA01
ATC
[U] cefalexin; systemic
1.4
14.3
1285
8911
LBF60
NOMESCO Finland
Partial excision and anastomosis of Fallopian tube
132.0
14.3
16
*
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
0.6
14.2
397
4593
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
15.3
14.2
24
13
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
27.5
14.2
20
6
SPAT1393
SPAT
Guidance to support interaction between parent and child
31.4
13.9
19
5
L02AE01
ATC
buserelin; implant, nasal, parenteral
3.7
13.9
61
136
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
13.8
273
1336
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
8.3
13.8
31
31
N61
ICD-10 Finland
Inflammatory disorders of breast
3.6
13.7
63
146
XLA00
NOMESCO Finland
NA
9.2
13.7
29
26
SPAT1283
SPAT
Restricted health certificate
1.5
13.7
585
3500
ZYC01
SPAT
NA
0.4
13.5
71
1300
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
13.5
1646
12014
Z31.0
ICD-10 Finland
Tuboplasty or vasoplasty after previous sterilization
+∞
13.5
14
*
Z36.1
ICD-10 Finland
Antenatal screening for raised alphafetoprotein level
+∞
13.5
14
*
O68.2
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly with meconium in amniotic fluid
26.2
13.4
19
6
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
123.7
13.3
15
*
W27
ICPC
Fear of complications of pregnancy
123.7
13.3
15
*
SPAT1187
SPAT
General ultrasound examination in early pregnancy
123.7
13.3
15
*
G03GA02
ATC
human menopausal gonadotrophin; parenteral
2.9
13.3
81
231
R3110
NOMESCO Finland
Psychosocial training
20.7
13.2
20
8
OAB39
SPAT
NA
0.4
13.2
42
936
O03.0
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection
15.2
13.1
22
12
O33.9
ICD-10 Finland
Maternal care for disproportion, unspecified
35.1
12.8
17
*
LCA30
NOMESCO Finland
Transfer of oocyte or embryo to uterus in assisted fertilisation
9.8
12.7
26
22
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
44.0
12.6
16
*
O16
ICD-10 Finland
Unspecified maternal hypertension
44.0
12.6
16
*
O35.2
ICD-10 Finland
Maternal care for (suspected) hereditary disease in fetus
+∞
12.5
13
*
O41.8
ICD-10 Finland
Other specified disorders of amniotic fluid and membranes
+∞
12.5
13
*
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
12.5
1195
8289
O85
ICD-10 Finland
Puerperal sepsis
28.1
12.2
17
5
O14.1
ICD-10 Finland
Severe pre-eclampsia
21.2
12.0
18
7
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
21.2
12.0
18
7
O69.1
ICD-10 Finland
Labour and delivery complicated by cord around neck, with compression
33.0
11.9
16
*
O70.0
ICD-10 Finland
First degree perineal laceration during delivery
17.4
11.9
19
9
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
4.1
11.8
46
93
O68.8
ICD-10 Finland
Labour and delivery complicated by other evidence of fetal stress
23.4
11.7
17
6
O71.4
ICD-10 Finland
Obstetric high vaginal laceration
+∞
11.6
12
*
O47
ICD-10 Finland
False labour
57.8
11.5
14
*
MA2AE
SPAT
NA
57.8
11.5
14
*
G02AB01
ATC
methylergometrine; systemic
13.8
11.5
20
12
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
10.7
11.3
22
17
O80.9
ICD-10 Finland
Single spontaneous delivery, unspecified
8.3
11.2
25
25
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
12.7
11.2
20
13
O36.3
ICD-10 Finland
Maternal care for signs of fetal hypoxia
31.0
11.1
15
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.3
11.0
106
394
M01AX17
ATC
nimesulide; oral
0.6
10.9
203
2581
O36.4
ICD-10 Finland
Maternal care for intrauterine death
22.0
10.8
16
6
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
38.5
10.8
14
*
O61.0
ICD-10 Finland
Failed medical induction of labour
13.1
10.8
19
12
Z39
ICD-10 Finland
Postpartum care and examination
+∞
10.6
11
*
K02.1
ICD-10 Finland
Caries of dentine
1.3
10.6
1281
9119
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
98.9
10.5
12
*
W03
ICPC
Antepartum bleeding
98.9
10.5
12
*
MAG00
NOMESCO Finland
Assisted breech delivery
18.9
10.4
16
7
O75.0
ICD-10 Finland
Maternal distress during labour and delivery
15.6
10.3
17
9
N97.0
ICD-10 Finland
Female infertility associated with anovulation
6.1
10.3
28
38
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
10.3
727
4741
Z2221
NOMESCO Finland
Medical doctor
1.4
10.2
485
2944
TLW00
NOMESCO Finland
Insemination
11.2
10.1
19
14
WX740
NOMESCO Finland
Nitrogen oxide therapy
20.6
10.0
15
6
O03.6
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by delayed or excessive haemorrhage
10.5
9.8
19
15
O32.0
ICD-10 Finland
Maternal care for unstable lie
49.4
9.7
12
*
MBC33
NOMESCO Finland
Repair of complete rupture of perineum
+∞
9.6
10
*
H01
ICPC
Ear pain/earache
1.6
9.5
286
1569
LCH13
NOMESCO Finland
Vacuum aspiration from uterus after medically induced abortion
4.7
9.4
32
57
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.7
9.4
208
1050
A05
ICPC
Feeling ill
1.6
9.3
285
1569
D10
ICPC
Vomiting
1.9
9.3
146
664
IHZ05
SPAT
NA
0.4
9.3
28
637
G01AF05
ATC
econazole; vaginal
1.6
9.2
222
1148
LCD00
NOMESCO Finland
Hysterectomy
0.4
8.9
35
714
SPAT1192
SPAT
Gynaecological examination
1.7
8.8
206
1056
H01CC01
ATC
ganirelix; parenteral
6.3
8.8
23
30
MA3AE
SPAT
NA
45.3
8.8
11
*
O23.1
ICD-10 Finland
Infections of bladder in pregnancy
45.3
8.8
11
*
O61.8
ICD-10 Finland
Other failed induction of labour
45.3
8.8
11
*
O12.0
ICD-10 Finland
Gestational oedema
45.3
8.8
11
*
TLC02
NOMESCO Finland
Simple extraction of IUD
2.4
8.8
75
263
O99.8
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
16.5
8.8
14
7
FM1NE
NOMESCO Finland
Ultrasound examination of fetal heart
+∞
8.7
9
*
Z31.2
ICD-10 Finland
In vitrofertilization
+∞
8.7
9
*
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
+∞
8.7
9
*
O83.8
ICD-10 Finland
Other specified assisted single delivery
82.3
8.6
10
*
MBC20
NOMESCO Finland
Repair of obstetric laceration of vulva
82.3
8.6
10
*
WX290
NOMESCO Finland
Other blockade of nerve
1.3
8.6
1057
7440
205
Kela drug reimbursment
Chronic hypertension
0.6
8.6
103
1456
LCH03
NOMESCO Finland
Evacuation of products of conception and curettage of uterus
3.8
8.5
35
76
OAB36
SPAT
NA
0.2
8.5
9
350
K04.08
ICD-10 Finland
Other specified pulpit
1.9
8.5
130
587
N96
ICD-10 Finland
Habitual aborter
17.9
8.4
13
6
N01
ICPC
Headache
1.4
8.4
436
2681
WYA50
NOMESCO Finland
Student oral health check consistent with decree to assess need for oral health guidance and services
0.4
8.4
46
827
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
3.0
8.3
47
130
MA5AE
SPAT
NA
30.2
8.2
11
*
O24.1
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
30.2
8.2
11
*
SPAT1246
SPAT
Screening of depression or other psychiatric problem
1.9
8.1
116
510
KMAK
NOMESCO Finland
NA
1.3
8.1
917
6362
TQX20
NOMESCO Finland
Implantation of subcutaneous medicament implant
8.8
8.1
17
16
J01CA04
ATC
amoxicillin; systemic
1.4
8.1
1863
14289
Z71.8
ICD-10 Finland
Other specified counselling
1.4
8.1
497
3144
O00.1
ICD-10 Finland
Tubal pregnancy
4.3
8.0
29
56
L02AE02
ATC
leuprorelin; implant, parenteral
4.0
8.0
31
64
J01CA08
ATC
pivmecillinam; oral
1.3
8.0
963
6742
Z31.4
ICD-10 Finland
Procreative investigation and testing
41.1
7.9
10
*
R21
ICPC
Throat symptom/complaint
1.4
7.9
561
3633
N76.0
ICD-10 Finland
Acute vaginitis
1.7
7.9
151
731
D01
ICPC
Abdominal pain/cramps general
1.5
7.7
278
1586
ZXD00
NOMESCO Finland
Emergency procedure
3.3
7.7
38
96
O22.3
ICD-10 Finland
Deep phlebothrombosis in pregnancy
+∞
7.7
8
*
NE1AG
NOMESCO Finland
MRI pelvimetry with high intensity magnet
+∞
7.7
8
*
O22.4
ICD-10 Finland
Haemorrhoids in pregnancy
+∞
7.7
8
*
O62.0
ICD-10 Finland
Primary inadequate contractions
13.4
7.6
13
8
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
7.4
1239
9015
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
10.5
7.4
14
11
OAB47
SPAT
NA
0.3
7.3
19
461
QXA70
SPAT
NA
0.1
7.2
*
238
G02CB03
ATC
cabergoline; oral (prolactine inhibitors)
8.8
7.2
15
14
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
18.1
7.2
11
5
O64.8
ICD-10 Finland
Obstructed labour due to other malposition and malpresentation
18.1
7.2
11
5
C03CA01
ATC
furosemide; systemic
0.6
7.2
101
1372
P23
ICPC
Adolescent behaviour sympt/compl
2.8
7.1
43
126
WX320
NOMESCO Finland
Spinalanesthesy
1.4
7.1
311
1848
OAB44
SPAT
NA
0.5
7.1
53
859
IGY99
SPAT
NA
0.2
7.1
10
329
Z30.5
ICD-10 Finland
Surveillance of (intrauterine) contraceptive device
1.8
7.1
109
494
O68.1
ICD-10 Finland
Labour and delivery complicated by meconium in amniotic fluid
37.0
7.0
9
*
O86.8
ICD-10 Finland
Other specified puerperal infections
37.0
7.0
9
*
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
7.0
1956
15202
C10AA01
ATC
simvastatin; oral
0.7
7.0
239
2704
O33.3
ICD-10 Finland
Maternal care for disproportion due to outlet contraction of pelvis
10.7
6.9
13
10
D10BA01
ATC
isotretinoin; oral
0.5
6.9
49
808
D06
ICPC
Abdominal pain localized other
1.6
6.9
170
887
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.9
6.9
41
119
N97.4
ICD-10 Finland
Female infertility associated with male factors
4.8
6.9
22
38
M54.5
ICD-10 Finland
Low back pain
1.3
6.9
606
4043
WX110
NOMESCO Finland
Local anesthesy
1.3
6.8
1501
11246
SPAT1307
SPAT
Psychosocial counselling and guidance
1.5
6.8
228
1280
O33.5
ICD-10 Finland
Maternal care for disproportion due to unusually large fetus
20.6
6.8
10
*
O33.1
ICD-10 Finland
Maternal care for disproportion due to generally contracted pelvis
20.6
6.8
10
*
SPAT1364
SPAT
Health check-up performed during second study year in students of upper secondary schools, vocational schools etc.
0.7
6.8
161
1951
Z32
ICD-10 Finland
Pregnancy examination and test
65.8
6.8
8
*
W78
ICD-10 Finland
Inhalation of gastric contents
65.8
6.8
8
*
W94
ICPC
Puerperal mastitis
65.8
6.8
8
*
O03
ICD-10 Finland
Spontaneous abortion
65.8
6.8
8
*
O04.0
ICD-10 Finland
Medical abortion, incomplete, complicated by genital tract and pelvic infection
15.1
6.8
11
6
O90.9
ICD-10 Finland
Complication of the puerperium, unspecified
+∞
6.7
7
*
O26.80
ICD-10 Finland
Gingivitis associated with pregnancy
+∞
6.7
7
*
O46.8
ICD-10 Finland
Other antepartum haemorrhage
+∞
6.7
7
*
O20
ICD-10 Finland
Haemorrhage in early pregnancy
+∞
6.7
7
*
ZXD20
NOMESCO Finland
Day surgery
1.5
6.7
241
1373
D09
ICPC
Nausea
1.6
6.7
166
867
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.4
6.7
54
187
Z30.8
ICD-10 Finland
Other contraceptive management
2.1
6.7
76
309
ZYC05
SPAT
NA
0.3
6.6
14
375
SGA01
NOMESCO Finland
Tooth opening as first aid
1.4
6.5
313
1895
G03DB01
ATC
dydrogesterone; oral
1.4
6.5
359
2227
G01AF04
ATC
miconazole; vaginal
1.7
6.4
131
652
WX600
NOMESCO Finland
Single shot through catheter
4.3
6.3
22
42
D25.9
ICD-10 Finland
Leiomyoma of uterus, unspecified
0.6
6.3
123
1547
O80.1
ICD-10 Finland
Spontaneous breech delivery
9.9
6.2
12
10
IHZ02
SPAT
NA
0.3
6.2
11
318
O86.4
ICD-10 Finland
Pyrexia of unknown origin following delivery
32.9
6.1
8
*
O35.4
ICD-10 Finland
Maternal care for (suspected) damage to fetus from alcohol
32.9
6.1
8
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
6.1
1043
7535
Z29
ICPC
Social problem NOS
2.6
6.1
43
138
8513
FHL
Softening of cervix with abortifacient or laminars and associated surgical emptying of the uterus
2.2
6.0
58
220
J01FA01
ATC
erythromycin; systemic
1.4
6.0
246
1439
SPAT1196
SPAT
Monitoring of normal pregnancy
18.5
6.0
9
*
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
18.5
6.0
9
*

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: Z21_ANTEN_SCREE – Antenatal screening

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).