Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder

CD2_BENIGN_CONNSOFT_UPPERLIMB

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D21.1&
  • Hospital discharge: ICD-9 2152
  • Hospital discharge: ICD-8 21503
  • Cause of death: ICD-10 D21.1&
  • Cause of death: ICD-9 2152
  • Cause of death: ICD-8 21503

2 out of 7 registries used, show all original rules.

1709

4. Check minimum number of events

None

1709

5. Include endpoints

None

1709

6. Filter based on genotype QC (FinnGen only)

1709

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D21
Name in latin
Neoplasma benignum textus connectivi/textus mollis regionis deltoideae

Similar endpoints

List of similar endpoints to Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11643 6413 5178
Only index persons 10885 6072 4813
Unadjusted period prevalence (%)
Whole population 0.17 0.18 0.14
Only index persons 0.21 0.22 0.18
Median age at first event (years)
Whole population 46.94 47.68 45.95
Only index persons 46.41 47.26 45.33

-FinnGen-

Key figures

All Female Male
Number of individuals 1709 1042 667
Unadjusted period prevalence (%) 0.33 0.36 0.29
Median age at first event (years) 50.03 48.71 52.10

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1530
Matched controls
15297
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
144.1
323.0
498
51
D21.1
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder
4503599627370496.0
323.0
1250
*
21503
ICD-8 Finland
Other benign neoplasm of muscular and connective tissue, Extremitatis superioris (regione scapulari inclusa)
+∞
186.3
175
*
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
16.1
114.4
191
134
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
14.1
78.1
137
106
M67.4
ICD-10 Finland
Ganglion
5.6
74.1
235
481
NDR30
NOMESCO Finland
Complete excision of soft tissue tumour of wrist or hand
93.0
64.5
71
8
R22.3
ICD-10 Finland
Localized swelling, mass and lump, upper limb
12.2
57.4
107
94
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
11.3
57.0
110
104
2152A
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Upper limb, including shoulder[YLÄRAAJAN BENIGNI PEHMYTKUDOSKASVAIN,SIDEKUDOSPERÄI]
+∞
46.1
44
*
2152X
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Upper limb, including shoulder[YLÄRAAJAN BENIGNI PEHMYTKUDOSKASVAIN,TARK MÄÄRITTEL]
+∞
35.5
34
*
NDM99
NOMESCO Finland
Other operation on fascia, ganglion, synovial sheath or bursa of wrist or hand
18.2
32.9
51
29
SPAT1153
SPAT
Removal of sutures
1.9
26.0
509
3189
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.8
24.7
175
685
S18
ICPC
Laceration/cut
1.8
24.1
636
4374
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
7.5
22.8
54
74
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
52.8
22.1
26
5
2152D
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Upper limb, including shoulder[YLÄRAAJAN BENIGNI PEHMYTKUDOSKASVAIN,MUU]
+∞
21.9
21
*
WX204
NOMESCO Finland
Axillary plexus blockaced
4.3
21.9
83
201
D16.1
ICD-10 Finland
Benign neoplasm: Short bones of upper limb
21.8
20.8
30
14
9491
FHL
Local soft tissue exploration, drainage, or removal
15.8
19.3
31
20
ZXA00
NOMESCO Finland
Right side
1.8
19.0
413
2624
NCR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of elbow or forearm
55.7
18.9
22
*
N02BE01
ATC
paracetamol; systemic, rectal
1.9
18.4
1293
11413
D17.2
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
4.9
18.1
59
123
NDR99
NOMESCO Finland
Other operation for tumour of wrist or hand
182.0
17.5
18
*
D21.2
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of lower limb, including hip
14.0
17.3
29
21
ZXA05
NOMESCO Finland
Left side
1.8
17.1
385
2458
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
6.1
17.0
46
77
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.0
16.3
221
1181
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.6
16.2
125
512
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.2
16.0
167
798
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
3.7
15.5
69
195
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.7
15.3
365
2361
ND2CG
NOMESCO Finland
Extensive MRI of hand
17.9
15.2
23
13
WX702
NOMESCO Finland
Supraglottic ventilation device
2.7
14.4
100
384
S04
ICPC
Lump/swelling localized
2.2
14.1
148
707
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
3.6
13.6
62
179
QCE99
NOMESCO Finland
Other excision or repair of lesion of skin of upper limb
8.6
13.3
28
33
M01AH05
ATC
etoricoxib; oral
1.5
13.1
869
7154
WX400
NOMESCO Finland
Inhalation anesthesy
2.9
13.0
81
293
9474
FHL
Soft tissue tumor removal (subcutaneous tumor 9736 skin tumor 9733)
50.4
12.8
15
*
D36.1
ICD-10 Finland
Benign neoplasm: Peripheral nerves and autonomic nervous system
15.6
12.6
20
13
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
12.5
676
5303
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
6.6
12.3
31
48
D21.9
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue, unspecified
14.5
12.3
20
14
SPAT1301
SPAT
No procedures
1.5
12.0
439
3153
L12
ICPC
Hand/finger symptom/complaint
1.8
11.8
204
1186
M01AE01
ATC
ibuprofen; systemic, rectal
1.7
11.8
1344
12353
ND1DG
NOMESCO Finland
Wrist and hand very extensive MRI examination with high intensity magnet
30.3
11.6
15
5
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
11.3
217
1305
A02BC03
ATC
lansoprazole; oral
1.5
10.6
413
2995
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
10.1
10.5
20
20
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
2.2
10.4
107
507
WX720
NOMESCO Finland
Own respiration
2.7
10.3
69
262
M03BX02
ATC
tizanidine; oral
1.4
10.2
902
7679
ACC51
NOMESCO Finland
Release of median nerve
2.1
10.1
114
562
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
3.8
10.1
41
109
N03AX16
ATC
pregabalin; oral
1.6
10.0
335
2335
L08
ICPC
Shoulder symptom/complaint
1.6
10.0
259
1697
WX725
NOMESCO Finland
Noninvasive ventilation
2.5
10.0
77
317
WX704
NOMESCO Finland
Intubation
2.1
9.7
111
551
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.3
9.7
90
409
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
9.6
219
1383
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
3.0
9.5
54
185
ND3CG
NOMESCO Finland
Extensive MRI of fingers
30.2
9.4
12
*
N03AX12
ATC
gabapentin; oral
1.7
9.3
219
1397
M01AB05
ATC
diclofenac; systemic, rectal
1.4
9.0
955
8299
J01DB01
ATC
cefalexin; oral
1.5
8.9
1188
10767
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
4.1
8.9
33
82
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
8.9
522
4085
J01FA10
ATC
azithromycin; systemic
1.4
8.8
818
6936
M48.0
ICD-10 Finland
Spinal stenosis
1.8
8.8
156
914
D18.0
ICD-10 Finland
Haemangioma, any site
3.2
8.5
42
132
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.0
8.4
104
533
N02AX02
ATC
tramadol; systemic, rectal
1.4
8.4
577
4630
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
3.9
8.3
33
87
M01AC06
ATC
meloxicam; systemic, rectal
1.4
8.3
511
4025
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
2.0
8.3
105
547
SPAT1324
SPAT
Screening procedure
1.5
8.2
261
1794
C49.19
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder other or unspecified tumor
33.5
8.1
10
*
D48.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Peripheral nerves and autonomic nervous system
33.5
8.1
10
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
8.0
351
2588
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
2.2
7.9
75
343
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.0
7.8
103
544
WZA90
NOMESCO Finland
Other doctors statement
1.5
7.8
305
2195
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
7.7
274
1928
P01BA02
ATC
hydroxychloroquine; oral
1.9
7.7
120
672
SPAT1263
SPAT
Sampling
1.4
7.7
568
4598
XA402
NOMESCO Finland
ENMG
2.8
7.6
47
173
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
18.4
7.6
11
6
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
7.6
461
3608
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
2.7
7.5
49
186
M79.6
ICD-10 Finland
Pain in limb
1.4
7.5
483
3818
SPAT1285
SPAT
Provision of consultation response
2.2
7.4
74
348
SPAT1260
SPAT
Consultation of another employee
1.5
7.4
234
1607
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
3.1
7.4
38
125
2152C
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Upper limb, including shoulder[YLÄRAAJAN BENIGNI PEHMYTKUDOSKASVAIN,HERMOPERÄINEN]
+∞
7.3
7
*
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
7.3
983
8732
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.5
7.2
264
1870
NBR30
NOMESCO Finland
Extensive or radical excision of soft tissue tumour of shoulder or upper arm
30.1
7.1
9
*
NC1DG
NOMESCO Finland
Elbow and forearm very extensive MRI examination with high intensity magnet
20.1
7.1
10
5
WX110
NOMESCO Finland
Local anesthesy
1.3
7.0
966
8577
M54.2
ICD-10 Finland
Cervicalgia
1.9
6.8
100
551
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
2.9
6.8
39
135
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
3.5
6.8
30
88
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
6.8
518
4197
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.7
658
5537
SPAT1310
SPAT
Counselling related to known health issue
1.4
6.6
408
3187
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
6.5
143
894
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
5.7
6.5
17
30
9473
FHL
Local soft tissue removal or exploration (eg Bursa)
4.9
6.4
19
39
QCC00
NOMESCO Finland
Removal of foreign body from skin or subcutaneous tissue of upper limb
11.1
6.3
11
10
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.2
6.2
57
261
M25.5
ICD-10 Finland
Pain in joint
1.4
6.2
373
2898
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.5
6.2
195
1334
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
2.1
6.1
68
338
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
3.7
6.1
24
65
UJF32
NOMESCO Finland
Coloscopy
1.4
6.1
318
2411
N04BC04
ATC
ropinirole; oral
4.9
6.0
18
37

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
744
5870
1.47
13.38
4.6
4.8
36.1
35.7
g/l
1.00
694
5472
76
300
2.60
13.15
6.1
8.8
11.3
11.3
mmol/l
0.03
70
274
76
300
2.60
13.15
6.1
8.8
105.4
105.4
mmol/l
0.03
70
274
192
1098
1.84
13.03
4.0
3.3
—
—
—
0
0
1207
10503
1.51
12.97
4.8
4.0
11.5
11.8
mm/h
0.33
1126
9765
92
409
2.32
12.34
5.8
7.7
1.2
1.3
mmol/l
0.39
85
363
153
838
1.91
11.86
8.2
7.5
24.2
24.6
mmol/l
0.81
143
787
409
2955
1.50
10.97
4.5
3.9
1.0
1.0
kg/l
0.02
37
426
487
3650
1.47
10.86
4.6
3.8
0.0
0.0
estimate
1.28
171
1269
273
1824
1.59
10.38
1.3
1.3
—
—
—
0
0
151
879
1.79
9.64
5.8
5.3
—
—
—
0
0
343
2448
1.50
9.62
1.3
1.3
16.6
12.3
u/ml
0.41
148
961
1130
9992
1.39
9.01
4.0
3.6
—
—
—
0
0
662
5415
1.36
8.48
8.0
8.6
1.2
1.2
inr
0.37
207
1609
168
1050
1.67
8.31
2.8
2.7
133.7
189.4
ng/l
1.59
161
953
193
1260
1.60
8.02
6.9
9.3
122.5
121.5
g/l
0.23
184
1220
802
6824
1.33
7.65
4.0
3.5
0.0
0.0
estimate
0.00
165
1280
693
5773
1.34
7.65
2.3
2.1
—
—
—
0
0
933
8124
1.33
7.52
4.6
4.8
6.6
6.7
mmol/l
0.72
868
7600
1512
14235
1.54
7.42
14.5
13.4
21.6
23.0
mg/l
0.92
1229
11223
202
1357
1.55
7.42
6.6
8.8
96.4
95.7
%
1.15
195
1313
807
6913
1.32
7.17
4.0
3.5
0.0
0.0
estimate
1.08
165
1249
97
541
1.84
7.16
5.7
6.1
1.0
0.9
%
1.26
91
509
771
6583
1.31
6.94
4.5
3.9
—
—
—
0
0
342
2586
1.40
6.86
3.4
3.5
354.1
417.9
ng/l
0.14
242
1926
1566
14909
1.60
6.76
14.1
12.7
—
—
—
0
0
218
1522
1.50
6.68
6.5
8.3
5.0
5.1
kpa
1.36
210
1467
218
1522
1.50
6.68
6.5
8.3
12.3
12.4
kpa
0.12
210
1467
411
3221
1.36
6.61
5.2
4.6
—
—
—
0
0
509
4122
1.33
6.59
2.1
2.1
172.4
219.3
u/l
0.83
482
3894
217
1518
1.49
6.59
6.5
8.3
1.2
1.2
mmol/l
0.00
160
1200
794
6850
1.30
6.45
4.9
4.8
0.0
0.0
estimate
0.41
171
1300
338
2588
1.38
6.25
1.3
1.3
42.7
31.9
iu/ml
0.59
118
840
115
704
1.68
6.19
6.9
12.1
—
—
—
0
0
94
545
1.77
6.15
5.7
6.1
2.1
1.6
%
2.85
88
513
32
127
2.55
5.63
1.6
1.4
23.3
30.9
%
0.56
12
79
1010
9088
1.27
5.49
4.5
4.2
3849.6
2229.7
e6/l
0.18
13
132
1640
15895
1.79
5.37
21.6
19.9
136.0
135.8
g/l
0.22
1628
15685
1285
11935
1.31
5.36
16.0
16.3
13.7
13.7
%
0.13
1261
11679
1532
14625
1.46
5.32
16.0
15.3
4.0
4.0
mmol/l
0.37
1504
14253
1528
14580
1.45
5.32
15.9
15.2
139.8
139.7
mmol/l
1.46
1501
14228
1638
15887
1.75
5.11
21.4
19.7
90.7
90.9
fl
1.01
1626
15683
1638
15890
1.74
5.07
21.4
19.7
30.3
30.3
pg
0.00
1626
15684
1637
15878
1.74
5.06
21.5
19.8
256.2
253.3
e9/l
1.12
1618
15516
1638
15891
1.74
5.05
21.5
19.8
4.5
4.5
e12/l
0.45
1616
15484
1638
15894
1.74
5.01
21.5
19.8
6.6
6.7
e9/l
1.07
1613
15488
775
6808
1.25
4.97
6.7
6.7
1.2
1.2
mmol/l
0.06
652
5777
385
3125
1.30
4.69
4.4
3.5
—
—
—
0
0
445
3694
1.28
4.53
2.7
2.6
2331.3
5316.5
umol/l
1.21
388
3222
520
4430
1.25
4.20
2.7
2.5
56.4
57.0
u/l
0.14
490
4108
790
7056
1.22
4.06
6.3
5.9
0.0
0.0
e9/l
0.56
725
6169
1045
9604
1.23
4.04
4.6
4.2
—
—
—
0
0
253
1980
1.33
3.98
1.8
2.0
—
—
—
0
0
786
7029
1.22
3.95
6.3
5.9
0.6
0.6
e9/l
0.58
720
6133
6
225
0.26
3.92
7.8
5.9
378.7
365.9
umol/l
—
6
202
87
561
1.58
3.90
1.4
1.3
0.9
1.0
u/ml
—
7
43
288
3553
0.77
3.87
3.3
3.8
91.4
92.1
%
0.20
277
3460
1170
10912
1.23
3.78
8.0
7.5
75.9
77.4
u/l
0.49
1114
10305
1374
13054
1.27
3.69
5.0
4.8
1.8
2.1
mu/l
1.07
1285
12037
695
6170
1.21
3.68
5.9
6.0
1.2
1.2
mmol/l
0.11
631
5619
1376
13087
1.26
3.59
5.7
5.5
39.1
39.6
mmol/mol
1.39
1299
12184
809
7302
1.20
3.57
6.4
6.1
0.2
0.2
e9/l
0.94
750
6468
472
4043
1.23
3.54
4.1
4.0
7.4
7.4
ph
0.23
82
774
798
7214
1.20
3.41
6.4
5.9
1.9
2.0
e9/l
1.26
742
6425
80
526
1.55
3.34
6.2
4.5
—
—
—
0
0
589
5192
1.21
3.27
3.3
3.4
25.2
57.4
ng/l
2.14
362
3432
22
98
2.26
3.13
1.2
1.1
—
—
—
0
0
1171
11009
1.20
3.11
4.4
4.0
14.8
14.7
pmol/l
0.48
1095
10110
891
8182
1.19
3.07
9.1
9.2
4.0
4.0
e9/l
0.07
816
7212
463
4017
1.21
3.00
2.9
2.9
—
—
—
0
0
203
1605
1.30
2.99
1.8
1.7
—
—
—
0
0
460
3991
1.21
2.98
3.3
3.3
628.8
409.4
mg/l
0.32
279
2504
135
1010
1.37
2.90
1.4
1.4
—
—
—
0
0
20
89
2.26
2.87
5.4
6.6
—
—
—
0
0
805
7357
1.18
2.86
5.8
6.2
10.6
11.1
umol/l
0.62
765
7006
27
136
2.00
2.86
4.0
4.8
33.7
44.8
u/ml
—
7
42
1475
14234
1.26
2.83
4.7
4.4
4.7
4.7
mmol/l
0.84
1402
13282
1563
15197
1.33
2.82
11.4
10.2
26.9
26.6
u/l
0.20
1527
14727
204
1637
1.28
2.69
25.0
22.3
1.2
1.3
inr
0.30
25
217
414
3589
1.20
2.67
3.6
4.3
—
—
—
0
0
45
273
1.67
2.67
2.7
3.6
4.6
4.1
e9/l
0.32
45
273
21
99
2.14
2.65
1.4
1.0
—
—
—
0
0
1494
14460
1.26
2.65
5.1
4.8
2.8
2.8
mmol/l
0.37
1411
13414
333
2833
1.22
2.61
2.3
2.5
5.5
6.1
e6/l
0.36
293
2508
240
1972
1.25
2.60
1.4
1.3
588.2
541.4
titre
0.16
44
408
29
157
1.86
2.53
1.1
1.5
—
—
—
0
0
29
157
1.86
2.53
1.1
1.5
—
—
—
0
0
29
157
1.86
2.53
1.1
1.5
—
—
—
0
0
29
157
1.86
2.53
1.1
1.5
—
—
—
0
0
46
286
1.63
2.50
2.7
3.9
59.0
57.4
%
0.35
46
286
169
2113
0.78
2.50
2.9
2.8
3.9
2.6
e6/l
0.51
89
1149
531
4734
1.18
2.47
5.5
5.8
—
—
—
0
0
76
531
1.45
2.45
2.2
2.0
1.8
1.8
ug/l
0.04
70
479
94
683
1.40
2.45
2.4
2.4
—
—
—
0
0
11
268
0.41
2.44
2.8
2.9
8.0
7.4
mmol/l
0.32
11
260
386
3356
1.19
2.40
2.4
2.1
2.7
3.0
mg/l
1.52
350
2874
475
4208
1.18
2.37
3.9
4.0
8.7
8.8
mg/mmol
0.01
291
2624
152
1197
1.30
2.34
4.7
4.2
1.1
1.0
%
0.08
40
351
150
1184
1.29
2.28
4.1
3.7
—
—
—
0
0
439
3876
1.18
2.28
1.8
1.7
1.4
1.4
mmol/l
0.06
378
3277
13
287
0.45
2.28
2.5
2.8
1.5
1.5
mmol/l
0.26
13
276
38
231
1.66
2.27
1.5
1.4
—
—
—
0
0
39
616
0.62
2.26
3.6
3.5
—
—
—
0
0
419
3692
1.18
2.22
2.7
2.9
1149.7
1140.5
ng/l
0.02
370
3110
26
143
1.83
2.19
2.3
2.1
—
—
—
0
0
521
4677
1.16
2.19
3.2
3.4
2.4
2.4
mmol/l
0.13
465
4131
136
1068
1.30
2.16
5.0
4.3
0.0
0.7
%
1.02
28
273
69
487
1.43
2.14
5.3
3.8
1.3
1.4
mmol/l
0.49
69
477
7
20
3.51
2.05
1.4
1.5
—
—
—
0
0
664
6090
1.15
2.05
3.1
2.7
112.5
122.7
ug/l
0.67
632
5663
115
890
1.31
2.04
3.4
3.2
4.5
4.5
pmol/l
0.15
105
782
6
160
0.37
2.02
2.5
2.3
—
—
—
0
0
24
414
0.57
2.00
3.1
3.2
—
—
—
0
0
475
4269
1.16
1.94
3.2
3.2
7.8
7.5
mmol/l
0.52
405
3618
19
344
0.55
1.89
5.1
4.2
—
—
—
0
0
238
2024
1.20
1.89
1.3
1.2
—
—
—
0
0
136
1091
1.27
1.86
4.7
4.0
1.0
0.6
%
0.28
25
257
285
2468
1.19
1.85
2.5
3.0
2.5
2.4
mmol/l
0.32
255
2175
1456
14155
1.19
1.85
4.5
4.3
1.5
1.5
mmol/l
1.22
1375
13129
61
843
0.71
1.85
3.1
3.4
5.1
5.2
kpa
0.23
61
797
1425
13833
1.18
1.82
4.6
4.4
5.9
5.9
mmol/l
0.65
1337
12686
49
336
1.47
1.81
1.9
1.7
5114.6
12615.7
e6/l
2.24
34
246
24
138
1.75
1.79
1.4
1.3
4171.3
93550.3
e6/l
1.07
15
93
61
833
0.72
1.73
3.1
3.4
7.4
7.4
ph
—
10
109
14
68
2.07
1.70
1.0
1.3
244.2
429.0
u/l
0.57
14
62
12
238
0.50
1.63
1.3
1.5
—
—
—
0
0
14
70
2.01
1.59
1.4
1.6
—
—
—
0
0
22
129
1.71
1.57
1.2
1.4
0.4
0.4
g/l
0.35
14
89
22
129
1.71
1.57
1.2
1.4
2.9
2.8
g/l
0.04
14
88
22
129
1.71
1.57
1.2
1.4
8.8
7.1
g/l
0.31
14
89
421
3805
1.14
1.56
3.2
3.2
—
—
—
0
0
105
836
1.27
1.56
7.7
10.3
93.8
93.9
%
0.06
105
829
64
851
0.74
1.56
1.5
1.7
—
—
—
0
0
29
184
1.59
1.54
1.7
1.6
62.2
60.3
%
—
9
118
12
233
0.51
1.54
1.2
1.4
—
—
—
0
0
10
206
0.48
1.53
2.8
2.3
—
—
—
0
0
138
1138
1.23
1.52
5.0
4.3
0.0
0.1
%
2.43
34
323
12
231
0.52
1.51
1.2
1.4
—
—
—
0
0
15
79
1.91
1.49
1.1
1.1
1.1
1.1
ratio
—
5
32
32
211
1.53
1.46
1.3
1.7
0.5
0.9
g/l
1.44
19
161
22
133
1.66
1.42
1.2
1.4
—
—
—
0
0
234
2669
0.86
1.41
2.7
2.6
519.1
545.6
mosm/kgh2o
1.13
202
2295
34
493
0.68
1.41
2.6
3.5
0.2
0.3
g/l
0.52
14
208
362
3999
0.88
1.38
3.7
3.6
—
—
—
0
0
350
3154
1.14
1.36
1.3
1.2
2.2
1.4
u/ml
0.45
120
851
5
17
2.95
1.36
1.6
1.2
151.8
88.8
ng/l
—
5
17
55
409
1.36
1.36
2.9
2.2
6281.4
2680.9
u/l
0.40
20
164
250
2201
1.16
1.35
2.8
3.3
0.8
0.8
mmol/l
1.16
241
2073
237
2079
1.16
1.35
1.6
2.1
29.4
29.7
s
0.21
228
2017
0
40
0.00
1.32
0.0
1.0
—
—
—
0
0
97
784
1.25
1.31
1.3
1.2
—
—
—
0
0
15
83
1.81
1.31
2.4
1.7
19.3
8.8
ug/l
0.47
15
69
112
1354
0.82
1.31
4.1
4.1
—
—
—
0
0
69
536
1.30
1.28
1.1
1.1
—
—
—
0
0
342
3091
1.13
1.27
1.6
1.5
20.0
20.8
nmol/l
0.57
294
2649
15
84
1.79
1.27
1.0
1.1
—
—
—
0
0
102
833
1.24
1.27
7.8
10.2
0.7
0.7
%
0.37
102
826
300
3335
0.88
1.27
2.2
2.3
—
—
—
0
0
32
219
1.47
1.26
1.4
1.2
—
—
—
0
0
118
983
1.22
1.22
1.6
2.9
3.8
4.0
e9/l
0.61
101
783
32
221
1.46
1.21
1.1
1.2
—
—
—
0
0
102
839
1.23
1.20
7.8
10.1
1.5
1.4
%
0.92
102
832
17
101
1.69
1.20
3.5
2.9
35.8
42.0
%
—
9
29
14
79
1.78
1.17
1.0
1.0
—
—
—
0
0
8
152
0.52
1.14
1.0
1.1
—
—
—
0
0
35
250
1.41
1.13
3.0
2.9
—
—
—
0
0
78
958
0.81
1.09
1.6
1.4
—
—
—
0
0
5
21
2.38
1.09
2.2
1.7
—
—
—
0
0
14
231
0.60
1.09
1.1
1.2
2.8
5.4
u/ml
—
5
94
188
1654
1.15
1.06
6.2
7.4
104.4
104.3
mmol/l
0.14
181
1616
51
392
1.31
1.06
1.6
1.8
41.9
38.1
nmol/l
0.48
51
379
14
82
1.71
1.05
1.3
1.3
143.9
140.9
nmol/l
0.07
14
82
55
429
1.29
1.03
1.5
1.3
255.9
220.4
miu/ml
0.23
21
197
316
2881
1.12
1.03
1.6
1.7
32950613.1
36708761.9
pmol/l
0.04
261
2400
16
98
1.64
1.03
3.1
2.2
18.9
15.1
%
—
8
42
8
150
0.53
1.03
1.0
1.2
—
—
—
0
0
386
3559
1.11
1.03
6.4
6.6
—
—
—
0
0
408
4397
0.91
1.00
2.3
2.3
—
—
—
0
0
9
160
0.56
0.98
1.9
2.5
—
—
—
0
0
110
934
1.19
0.97
1.4
1.3
165.3
199.0
u/ml
0.34
105
861
17
108
1.58
0.96
1.2
1.5
1.7
1.2
promille
0.61
12
85
183
1623
1.14
0.94
1.5
1.7
—
—
—
0
0
93
781
1.20
0.94
3.0
3.2
219.8
49.3
u/ml
0.61
88
756
8
143
0.56
0.93
3.3
3.4
—
—
—
0
0
1347
13182
1.10
0.92
14.6
14.3
40.6
40.0
%
2.14
930
9722
76
630
1.22
0.88
1.8
1.8
—
—
—
0
0
155
1366
1.15
0.88
1.4
1.4
—
—
—
0
0
31
415
0.74
0.88
2.5
2.4
36.7
37.9
g/l
0.42
26
366
8
43
1.86
0.87
1.3
1.0
—
—
—
0
0
122
1059
1.16
0.86
4.0
3.7
95.3
83.3
ng/l
0.69
109
923
8
44
1.82
0.86
2.1
2.1
—
—
—
0
0
416
3886
1.09
0.85
5.0
4.6
2.1
2.3
ug/l
0.45
388
3489
32
239
1.35
0.84
1.2
1.6
—
—
—
0
0
25
179
1.40
0.84
2.3
2.6
—
—
—
0
0
41
318
1.30
0.84
2.1
2.1
—
—
—
0
0
177
1581
1.13
0.84
1.6
1.6
—
—
—
0
0
6
112
0.53
0.83
1.0
1.1
—
—
—
0
0
1392
13666
1.10
0.82
4.1
3.9
1.3
1.3
mmol/l
0.36
1312
12624
30
223
1.35
0.82
1.1
1.0
6.4
2.2
u/ml
1.01
16
102
19
272
0.70
0.82
1.3
1.2
296.8
258.0
u/ml
0.27
13
163
126
1102
1.15
0.81
3.3
2.8
10.1
10.6
g/l
0.54
113
1006
140
1236
1.14
0.79
1.4
1.4
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
10
163
0.61
0.78
1.2
1.2
—
—
—
0
0
192
1732
1.12
0.78
2.8
2.3
168.0
123.3
ug/g
0.72
158
1382
42
527
0.79
0.76
1.2
2.0
21.9
21.4
s
0.15
30
470
14
91
1.54
0.75
1.5
1.2
—
—
—
0
0
11
67
1.65
0.75
1.0
1.0
—
0.3
—
0
10
11
67
1.65
0.75
1.2
1.2
—
—
—
0
0
40
501
0.79
0.73
2.8
3.4
55.0
873.6
u/ml
1.45
29
429
5
25
2.00
0.72
7.2
7.4
—
—
—
0
0
125
1105
1.14
0.71
2.3
2.3
5.0
7.3
ug/l
1.39
117
987
228
2091
1.10
0.70
2.6
2.4
13.0
13.5
umol/l
0.44
213
1925
5
27
1.85
0.68
1.4
2.2
—
—
—
0
0
11
69
1.60
0.68
1.5
1.2
—
—
—
0
0
9
59
1.53
0.68
1.7
2.2
33.6
156.5
ug/l
—
9
50
30
232
1.30
0.66
1.3
1.2
—
—
—
0
0
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
55
458
1.21
0.66
11.1
9.8
—
—
—
0
0
57
477
1.20
0.65
1.6
1.8
—
—
—
0
0
7
44
1.59
0.65
1.0
1.1
—
—
—
0
0
103
906
1.15
0.65
1.3
1.3
69.0
42.3
au/ml
—
7
44
26
337
0.77
0.64
1.9
2.7
24.7
25.0
mmol/l
0.12
26
301
57
480
1.19
0.62
1.6
1.9
—
—
—
0
0
57
480
1.19
0.62
1.6
1.9
—
—
—
0
0
48
576
0.83
0.61
1.4
2.0
1.5
1.6
g/l
0.11
42
499
197
1810
1.10
0.60
5.0
5.6
1.0
1.0
mmol/l
0.07
181
1673
0
21
0.00
0.60
0.0
2.1
—
3.5
—
0
7
0
22
0.00
0.59
0.0
4.1
—
44.4
—
0
15
18
131
1.38
0.59
3.1
2.3
1.1
1.1
e9/l
0.02
13
80
41
336
1.23
0.59
2.1
2.4
122.8
115.2
ug/min
0.04
23
208
57
483
1.19
0.58
1.6
1.9
—
—
—
0
0
69
596
1.16
0.57
1.3
1.2
—
—
—
0
0
11
73
1.51
0.56
1.2
1.4
—
—
—
0
0
666
6426
1.06
0.56
6.3
6.0
0.7
0.7
%
1.43
635
6021
145
1319
1.11
0.55
1.8
2.2
0.2
0.2
g/l
0.18
121
1240
10
148
0.67
0.55
2.5
2.3
—
—
—
0
0
18
133
1.36
0.55
2.4
3.5
66.8
54.0
%
3.29
11
96
685
6618
1.06
0.55
6.3
6.0
3.0
2.8
%
0.81
652
6187
6
38
1.58
0.54
1.2
1.2
—
—
—
0
0
11
159
0.69
0.54
2.0
2.3
—
—
—
0
0
27
213
1.27
0.54
1.3
1.2
—
—
—
0
0
50
425
1.18
0.51
1.1
1.2
—
—
—
0
0
186
1721
1.09
0.51
1.2
1.4
—
—
—
0
0
24
303
0.79
0.51
1.1
2.0
0.9
0.9
nmol/l
0.14
18
257
36
434
0.83
0.51
1.1
1.2
—
—
—
0
0
110
992
1.12
0.50
2.4
2.4
28.4
23.0
au/ml
—
9
58
262
2780
0.93
0.48
1.6
1.5
2.4
2.4
g/l
0.06
175
1741
215
2296
0.93
0.47
3.1
2.9
0.8
0.7
ug/l
0.13
130
1434
28
227
1.24
0.46
1.5
1.5
—
—
—
0
0
154
1421
1.09
0.46
1.4
1.4
—
—
—
0
0
12
165
0.73
0.46
1.2
1.2
—
—
—
0
0
686
6655
1.05
0.46
6.5
6.2
8.5
8.5
%
0.01
659
6252
389
3718
1.06
0.45
2.9
3.0
0.5
0.5
e6/l
0.03
311
2827
46
394
1.17
0.45
1.1
1.3
—
1094.2
—
0
12
7
50
1.40
0.45
2.0
1.3
—
—
—
0
0
21
166
1.27
0.43
1.9
1.6
—
—
—
0
0
5
31
1.61
0.43
1.6
1.3
—
—
—
0
0
213
2001
1.07
0.42
1.5
1.6
—
—
—
0
0
144
1332
1.09
0.42
2.0
2.2
361.7
368.8
nmol/l
0.19
126
1226
12
87
1.38
0.42
1.0
1.6
—
10.1
—
0
8
5
32
1.56
0.42
7.2
6.7
—
—
—
0
0
13
173
0.75
0.42
1.2
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
8
59
1.36
0.41
1.0
1.2
537.4
248.0
iu/ml
—
8
59
371
3870
0.95
0.40
1.4
1.4
—
—
—
0
0
15
114
1.32
0.40
1.2
1.4
10.8
12.4
mmol/l
—
6
29
0
17
0.00
0.40
0.0
5.9
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
122.6
—
0
7
23
282
0.81
0.40
1.2
1.3
—
—
—
0
0
5
34
1.47
0.40
1.2
1.1
—
—
—
0
0
5
34
1.47
0.40
1.2
1.1
—
—
—
0
0
5
34
1.47
0.40
1.2
1.1
—
—
—
0
0
21
260
0.81
0.40
1.2
1.6
—
—
—
0
0
42
486
0.86
0.40
2.5
2.6
—
—
—
0
0
8
60
1.33
0.40
6.9
2.7
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
643
6258
1.04
0.37
9.2
9.4
0.0
0.0
e9/l
0.62
564
5178
5
37
1.35
0.37
1.0
1.3
26.6
80.8
mu/l
—
5
28
31
262
1.19
0.37
1.7
1.6
—
—
—
0
0
31
364
0.85
0.36
1.5
1.3
—
—
—
0
0
5
77
0.65
0.35
1.4
2.8
—
—
—
0
0
61
680
0.89
0.35
3.3
3.3
—
—
—
0
0
9
122
0.74
0.35
1.8
1.5
—
—
—
0
0
9
122
0.74
0.35
1.4
1.3
—
—
—
0
0
29
245
1.19
0.35
1.0
1.1
—
—
—
0
0
556
5406
1.04
0.34
2.7
2.8
—
—
—
0
0
35
304
1.15
0.32
1.5
1.8
—
—
—
0
0
15
119
1.26
0.31
1.3
1.4
1.0
1.0
g/l
0.30
15
119
26
222
1.17
0.29
2.3
3.5
1.3
1.5
%
0.13
19
185
698
6835
1.04
0.29
6.3
6.0
28.5
28.2
%
0.28
670
6394
171
1622
1.06
0.29
1.5
1.3
—
—
—
0
0
112
1047
1.07
0.29
2.2
2.9
68.0
70.8
e9/l
0.42
90
815
67
613
1.10
0.28
2.6
2.4
1.4
1.2
%
0.46
67
608
111
1039
1.07
0.28
1.3
1.4
—
—
—
0
0
30
261
1.15
0.27
1.2
1.2
—
—
—
0
0
120
1127
1.07
0.27
1.1
1.2
—
—
—
0
0
9
121
0.74
0.27
2.4
2.0
—
42.3
—
0
14
28
321
0.87
0.26
1.9
2.6
—
—
—
0
0
32
281
1.14
0.26
3.3
3.6
—
—
—
0
0
94
878
1.07
0.25
2.1
1.8
1.4
1.4
g/l
0.07
84
809
12
149
0.80
0.25
2.3
2.7
—
—
—
0
0
202
1934
1.05
0.25
2.7
2.4
2.4
2.4
g/l
1.39
189
1791
32
360
0.89
0.24
2.0
1.9
3.0
5.0
iu/l
1.81
13
123
28
246
1.14
0.23
1.0
1.1
—
—
—
0
0
27
237
1.14
0.23
1.1
1.1
—
—
—
0
0
27
237
1.14
0.23
1.0
1.1
4.5
4.2
u/ml
0.04
12
121
103
971
1.06
0.23
2.1
2.2
13.2
13.1
nmol/l
0.03
93
861
397
4073
0.97
0.22
3.1
3.1
301.1
71.0
e6/l
0.40
325
3153
7
92
0.76
0.22
3.1
3.7
—
—
—
0
0
44
400
1.10
0.22
1.1
1.1
—
—
—
0
0
5
40
1.25
0.22
1.0
1.2
195.2
314.5
pmol/l
—
5
27
5
40
1.25
0.22
1.6
1.6
—
—
—
0
0
26
229
1.14
0.21
1.0
1.1
0.5
1.3
u/ml
—
10
96
14
167
0.84
0.21
1.3
1.4
—
—
—
0
0
10
124
0.81
0.21
1.8
1.4
2.7
3.7
ug/l
—
10
107
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
125
1313
0.95
0.21
2.2
2.4
144.3
39.5
u/l
0.46
104
1132
374
3646
1.03
0.21
2.7
2.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
173.2
—
0
5
0
13
0.00
0.21
0.0
6.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
35.6
—
0
14
16
187
0.85
0.20
1.0
1.0
8.4
2.8
u/ml
—
6
71
13
155
0.84
0.20
1.4
1.5
—
—
—
0
0
9
111
0.81
0.20
1.0
1.4
—
—
—
0
0
6
49
1.23
0.20
1.0
1.5
—
—
—
0
0
6
51
1.18
0.19
1.3
1.3
158.8
140.6
nmol/l
—
6
39
21
184
1.14
0.19
3.4
2.5
—
—
—
0
0
186
1797
1.04
0.18
2.7
2.5
22.0
23.4
%
0.63
152
1533
683
6734
1.02
0.17
6.2
5.8
56.6
57.0
%
0.39
658
6324
108
1131
0.95
0.17
1.7
1.6
—
—
—
0
0
106
1110
0.95
0.17
3.0
2.9
67.2
66.8
g/l
0.20
99
1018
23
205
1.12
0.17
1.1
1.3
—
0.4
nmol/l
—
0
17
21
236
0.89
0.17
2.0
2.5
—
—
—
0
0
27
298
0.90
0.16
3.0
3.8
35.4
24.8
mg/l
0.58
17
184
8
70
1.14
0.16
2.1
1.2
—
—
—
0
0
154
1486
1.04
0.16
1.3
1.4
—
—
—
0
0
63
593
1.06
0.16
2.5
2.3
0.7
0.7
%
0.67
57
576
30
273
1.10
0.16
2.7
2.6
—
—
—
0
0
11
130
0.85
0.16
1.5
1.5
—
—
—
0
0
12
140
0.86
0.15
1.0
1.1
—
—
—
0
0
12
102
1.18
0.15
2.1
1.7
10.6
10.9
%
0.08
12
102
84
802
1.05
0.14
2.9
2.9
122.3
129.1
g/l
1.82
79
784
42
392
1.07
0.14
2.0
3.1
1.4
1.5
mg/l
0.35
37
365
10
84
1.19
0.14
1.2
1.9
—
—
—
0
0
14
122
1.15
0.13
1.6
1.3
38474.9
125332.4
e6/l
—
8
65
22
199
1.11
0.13
1.4
2.3
—
4.8
—
0
5
105
1011
1.04
0.13
1.2
1.2
115.3
142.3
iu/ml
0.36
44
392
20
180
1.11
0.13
1.2
1.3
—
—
nmol/l
—
0
0
13
113
1.15
0.13
1.6
1.5
18.7
12.7
umol/l
0.76
13
107
11
94
1.17
0.13
2.5
2.1
—
—
—
0
0
123
1190
1.04
0.12
3.3
3.4
5.7
5.8
kpa
0.62
118
1155
156
1603
0.97
0.12
2.8
2.7
7.4
8.0
umol/l
0.21
137
1405
35
374
0.93
0.11
1.8
1.8
—
—
—
0
0
244
2391
1.02
0.11
1.8
1.7
1343.9
1197.9
nmol/l
1.84
197
1823
80
769
1.04
0.11
6.6
7.9
25.2
24.9
mmol/l
0.21
80
763
17
153
1.11
0.11
3.1
4.0
—
—
—
0
0
28
260
1.08
0.10
1.0
1.1
0.1
2.0
u/ml
—
9
111
27
290
0.93
0.10
1.4
1.4
—
—
—
0
0
5
47
1.06
0.09
2.2
2.1
—
—
—
0
0
10
87
1.15
0.09
1.5
1.4
4.8
7.8
u/l
—
10
72
145
1416
1.03
0.09
2.2
2.7
1.7
1.8
%
0.45
124
1267
29
309
0.94
0.09
1.1
1.4
—
—
—
0
0
36
380
0.95
0.09
1.1
1.2
—
—
—
0
0
6
55
1.09
0.09
2.3
1.9
—
—
—
0
0
93
903
1.03
0.08
3.2
2.8
—
—
—
0
0
95
923
1.03
0.08
1.3
1.2
—
—
—
0
0
71
686
1.04
0.08
7.1
11.1
23.8
24.4
mmol/l
0.74
63
651
121
1181
1.03
0.08
3.3
3.5
1.8
2.0
mmol/l
0.24
94
950
5
62
0.81
0.08
2.2
2.5
—
—
—
0
0
325
3209
1.02
0.08
1.6
1.7
1.0
1.1
mg/l
0.37
257
2436
10
88
1.14
0.08
1.9
2.2
464.2
500.8
min
—
5
65
38
399
0.95
0.08
1.8
1.5
287.0
285.1
ug/g
0.02
23
236
7
66
1.06
0.08
1.7
1.1
674.3
1699.1
miu/ml
—
7
66
6
70
0.86
0.07
1.0
1.7
—
—
—
0
0
10
112
0.89
0.07
2.3
2.3
798.0
612.1
ml
—
5
76
64
661
0.97
0.07
1.0
1.1
—
—
—
0
0
7
80
0.87
0.07
2.3
2.1
2.2
3.4
ug/l
—
7
70
7
83
0.84
0.07
14.7
11.9
0.6
0.6
mmol/l
—
7
76
11
122
0.90
0.07
1.1
1.2
—
—
—
0
0
27
285
0.95
0.06
1.9
2.5
8.1
8.1
kpa
0.00
27
263
58
598
0.97
0.06
3.4
3.6
23.7
24.2
mmol/l
0.57
48
543
10
110
0.91
0.05
1.4
1.1
—
—
—
0
0
239
2415
0.99
0.05
1.7
1.7
—
—
—
0
0
25
239
1.05
0.04
1.4
1.4
—
—
—
0
0
92
936
0.98
0.04
3.0
2.6
—
—
—
0
0
14
131
1.07
0.03
1.0
1.3
—
—
—
0
0
15
141
1.06
0.03
1.3
1.1
—
—
—
0
0
25
240
1.04
0.03
1.4
1.2
13.9
38.7
u/l
1.86
20
204
20
191
1.05
0.03
1.1
1.3
—
—
—
0
0
45
440
1.02
0.02
1.7
2.0
—
—
—
0
0
477
4788
0.99
0.02
3.5
3.6
65.7
84.3
e6/l
0.37
371
3387
13
123
1.06
0.01
1.2
1.1
—
—
—
0
0
38
372
1.02
0.01
1.4
1.4
7.4
9.9
u/l
0.95
33
299
21
217
0.97
0.01
1.2
1.2
—
—
—
0
0
111
1118
0.99
0.01
4.9
3.8
1.2
1.2
mmol/l
1.13
94
971
54
547
0.99
0.01
1.7
1.6
—
—
—
0
0
14
146
0.96
0.00
1.9
1.6
—
—
—
0
0
18
174
1.03
0.00
1.1
1.1
1.0
3.0
u/ml
—
5
67
18
186
0.97
0.00
1.4
1.8
—
—
—
0
0
30
306
0.98
0.00
5.4
4.1
4.9
5.1
kpa
0.59
30
301
11
105
1.05
0.00
1.4
1.3
—
—
—
0
0
14
145
0.97
0.00
1.2
1.2
—
—
—
0
0
23
235
0.98
0.00
1.3
1.3
67.8
61.1
mmol/l
0.33
16
197
30
305
0.98
0.00
5.4
4.1
2.9
2.8
mmol/l
0.10
23
208
37
365
1.01
0.00
4.8
3.8
7.4
7.4
ph
0.87
30
300
31
306
1.01
0.00
5.4
4.1
8.4
8.7
kpa
0.42
31
301
31
314
0.99
0.00
6.3
4.1
—
—
—
0
0
41
412
1.00
0.00
4.2
3.8
1.3
1.8
ratio
—
6
35
109
1091
1.00
0.00
6.9
9.1
—
—
—
0
0
547
5469
1.00
0.00
2.1
1.9
93.9
96.2
pmol/l
0.59
274
2843
15
153
0.98
0.00
1.2
1.4
—
—
—
0
0
26
263
0.99
0.00
1.5
1.4
107.0
108.1
u/ml
—
8
54
139
1385
1.00
0.00
3.5
4.2
63.1
19.6
ug/l
0.33
118
1130
5
49
1.02
0.00
1.0
1.0
—
—
—
0
0
6
66
0.91
0.00
1.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
2.4
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
4.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
27
270
1.00
0.00
2.2
2.5
16.8
16.3
%
0.36
13
138
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
0.00
11.0
11.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
0.00
10.2
2.9
—
—
—
0
0
0
8
0.00
0.00
0.0
2.8
—
—
—
0
0
224
2240
1.00
0.00
2.5
2.6
1.3
1.1
e6/l
0.45
139
1276
8
83
0.96
0.00
1.4
1.1
—
—
—
0
0
7
75
0.93
0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
0.00
2.0
2.5
—
—
—
0
0
8
86
0.93
0.00
1.4
1.2
—
—
—
0
0
8
83
0.96
0.00
1.0
1.1
—
11.3
—
0
23
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
7
78
0.90
0.00
2.9
2.1
1.5
2.1
ug/l
—
7
67
0
8
0.00
0.00
0.0
1.6
—
16.9
—
0
8
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
23
230
1.00
0.00
1.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_CONNSOFT_UPPERLIMB and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_CONNSOFT_UPPERLIMB 0.94 [0.82, 1.08] 0.387
Birth year 0.99 [0.98, 1.0] 0.028

During the follow-up period (1.1.1998 — 31.12.2019), 318 out of 4348 females with CD2_BENIGN_CONNSOFT_UPPERLIMB died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_CONNSOFT_UPPERLIMB 0.861 [0.75, 0.99] 0.039
Birth year 0.99 [0.98, 1.0] 0.028

During the follow-up period (1.1.1998 — 31.12.2019), 344 out of 3643 males with CD2_BENIGN_CONNSOFT_UPPERLIMB died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_CONNSOFT_UPPERLIMB.

N-year risk Females Males
1 0.063% 0.184%
5 0.461% 1.067%
10 1.17% 2.703%
15 2.402% 5.095%
20 4.083% 8.63%

Relationships between endpoints

Index endpoint: CD2_BENIGN_CONNSOFT_UPPERLIMB – Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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