Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder

CD2_BENIGN_CONNSOFT_UPPERLIMB

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D21.1&
  • Hospital discharge: ICD-9 2152
  • Hospital discharge: ICD-8 21503
  • Cause of death: ICD-10 D21.1&
  • Cause of death: ICD-9 2152
  • Cause of death: ICD-8 21503

2 out of 7 registries used, show all original rules.

1775

4. Check minimum number of events

None

1775

5. Include endpoints

None

1775

6. Filter based on genotype QC (FinnGen only)

1713

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D21
Name in latin
Neoplasma benignum textus connectivi/textus mollis regionis deltoideae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11643 6413 5178
Only index persons 10885 6072 4813
Unadjusted period prevalence (%)
Whole population 0.17 0.18 0.14
Only index persons 0.21 0.22 0.18
Median age at first event (years)
Whole population 46.94 47.68 45.95
Only index persons 46.41 47.26 45.33

-FinnGen-

Key figures

All Female Male
Number of individuals 1713 1045 668
Unadjusted period prevalence (%) 0.35 0.37 0.31
Median age at first event (years) 50.55 49.09 52.82

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1775
Matched controls
17750
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
196.3
307.7
625
49
D21.1
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder
12226.1
307.7
1478
7
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
13.9
230.8
223
181
21503
ICD-8 Finland
Other benign neoplasm of muscular and connective tissue, Extremitatis superioris (regione scapulari inclusa)
+∞
199.9
188
*
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
12.7
162.0
163
140
M67.4
ICD-10 Finland
Ganglion
5.6
142.7
303
626
R22.3
ICD-10 Finland
Localized swelling, mass and lump, upper limb
11.4
136.9
147
139
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
11.5
124.9
133
124
NDR30
NOMESCO Finland
Complete excision of soft tissue tumour of wrist or hand
125.9
78.6
84
7
NDM99
NOMESCO Finland
Other operation on fascia, ganglion, synovial sheath or bursa of wrist or hand
20.6
76.0
58
29
D21.2
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of lower limb, including hip
22.8
51.9
38
17
2152A
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Upper limb, including shoulder[YLÄRAAJAN BENIGNI PEHMYTKUDOSKASVAIN,SIDEKUDOSPERÄI]
+∞
47.1
45
*
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
7.8
40.9
57
75
2152X
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Upper limb, including shoulder[YLÄRAAJAN BENIGNI PEHMYTKUDOSKASVAIN,TARK MÄÄRITTEL]
+∞
38.7
37
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.7
37.6
223
895
9491
FHL
Local soft tissue exploration, drainage, or removal
11.8
35.2
36
31
S18
ICPC
Laceration/cut
1.8
31.9
842
5913
SPAT1153
SPAT
Removal of sutures
1.9
31.7
605
3846
D17.2
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
4.7
31.7
75
166
WX204
NOMESCO Finland
Axillary plexus blockaced
3.7
30.4
98
274
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.3
27.8
231
1080
QCE99
NOMESCO Finland
Other excision or repair of lesion of skin of upper limb
10.2
26.5
30
30
WX702
NOMESCO Finland
Supraglottic ventilation device
2.6
22.8
133
527
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
3.5
22.5
79
234
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
6.2
22.4
38
62
SPAT1301
SPAT
No procedures
1.7
22.2
532
3543
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.7
22.0
476
3081
2152D
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Upper limb, including shoulder[YLÄRAAJAN BENIGNI PEHMYTKUDOSKASVAIN,MUU]
+∞
21.9
21
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.0
21.7
285
1579
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
22.5
21.7
31
14
D16.1
ICD-10 Finland
Benign neoplasm: Short bones of upper limb
20.3
21.7
32
16
NCR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of elbow or forearm
50.7
21.1
25
5
ZXA05
NOMESCO Finland
Left side
1.8
21.0
435
2776
L12
ICPC
Hand/finger symptom/complaint
1.9
20.9
303
1734
NDR99
NOMESCO Finland
Other operation for tumour of wrist or hand
212.4
20.6
21
*
N02BE01
ATC
paracetamol; systemic, rectal
2.1
20.6
1578
14110
ND2CG
NOMESCO Finland
Extensive MRI of hand
33.0
20.2
26
8
S04
ICPC
Lump/swelling localized
2.1
20.2
199
992
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.4
20.0
149
661
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
19.2
796
6030
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
4.1
19.1
52
129
ZXA00
NOMESCO Finland
Right side
1.7
18.6
457
3041
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
3.0
18.5
81
275
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
18.2
282
1643
WX720
NOMESCO Finland
Own respiration
2.6
18.0
107
428
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
4.0
17.2
48
121
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.1
17.0
161
790
WX400
NOMESCO Finland
Inhalation anesthesy
2.7
16.3
91
352
M01AH05
ATC
etoricoxib; oral
1.5
16.3
1099
9134
WX725
NOMESCO Finland
Noninvasive ventilation
2.4
16.2
112
481
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
3.5
15.4
52
150
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
15.1
733
5653
WX704
NOMESCO Finland
Intubation
2.1
15.1
151
756
ACC51
NOMESCO Finland
Release of median nerve
2.1
15.1
151
756
ZXD20
NOMESCO Finland
Day surgery
1.8
15.1
234
1361
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
15.0
265
1601
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
4.4
15.0
37
85
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.2
14.4
118
545
D36.1
ICD-10 Finland
Benign neoplasm: Peripheral nerves and autonomic nervous system
12.1
13.6
24
20
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.6
13.5
80
320
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
6.2
12.9
22
36
D18.0
ICD-10 Finland
Haemangioma, any site
3.1
12.9
54
179
N03AX16
ATC
[U] pregabalin
1.6
12.9
395
2743
SPAT1263
SPAT
Sampling
1.5
12.7
674
5242
N02AX02
ATC
tramadol; systemic, rectal
1.5
12.6
713
5611
ND1DG
NOMESCO Finland
Wrist and hand very extensive MRI examination with high intensity magnet
17.4
12.5
19
11
M01AE01
ATC
ibuprofen; systemic, rectal
1.8
12.4
1582
14605
A02BC03
ATC
lansoprazole; oral
1.5
12.3
485
3550
M03BX02
ATC
tizanidine; oral
1.4
12.3
1084
9243
D21.9
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue, unspecified
10.6
12.3
23
22
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.1
12.2
122
610
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
4.3
12.2
31
73
WX203
NOMESCO Finland
Infraclavicular plexus blockade
3.1
12.2
50
164
9473
FHL
Local soft tissue removal or exploration (eg Bursa)
5.3
12.0
24
46
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
2.0
11.9
123
623
M79.6
ICD-10 Finland
Pain in limb
1.4
11.9
697
5505
J01DB01
ATC
cefalexin; oral
1.5
11.7
1416
12768
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
5.6
11.7
22
40
ND3CG
NOMESCO Finland
Extensive MRI of fingers
30.2
11.6
15
5
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
11.5
373
2615
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
2.8
11.3
57
210
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
11.3
354
2463
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
11.3
585
4507
M48.0
ICD-10 Finland
Spinal stenosis
1.7
11.2
202
1225
SPAT1260
SPAT
Consultation of another employee
1.6
11.2
276
1817
N03AX12
ATC
[U] gabapentin; oral
1.6
11.1
281
1861
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
2.3
11.0
86
390
M01AC06
ATC
meloxicam; systemic, rectal
1.4
11.0
609
4742
J01FA10
ATC
azithromycin; systemic
1.4
11.0
960
8097
SPAT1324
SPAT
Screening procedure
1.6
10.9
312
2124
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
10.9
1210
10632
L08
ICPC
Shoulder symptom/complaint
1.5
10.9
357
2508
C49.19
ICD-10 Finland
Malignant tumor of connective tissue and soft tissue of upper extremity including shoulder other or unspecified tumor
+∞
10.4
10
*
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
10.2
300
2053
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
10.2
1191
10492
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
2.9
10.0
45
156
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
2.6
10.0
58
230
SFA20
NOMESCO Finland
Two-surface restoration
1.4
10.0
978
8348
WX120
NOMESCO Finland
Intravenous local anesthesy of arm
3.4
9.9
34
100
M01AB05
ATC
diclofenac; systemic, rectal
1.4
9.8
1121
9805
WZA90
NOMESCO Finland
Other medical or dental certificate
1.5
9.7
372
2691
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.9
9.7
123
670
XA402
NOMESCO Finland
ENMG
2.7
9.7
50
187
P01BA02
ATC
hydroxychloroquine; oral
1.8
9.6
139
789
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.8
9.6
133
745
N04BC04
ATC
ropinirole; oral
4.6
9.5
22
48
M54.5
ICD-10 Finland
Low back pain
1.4
9.3
590
4677
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
9.3
179
1105
9474
FHL
Soft tissue tumor removal (subcutaneous tumor 9736 skin tumor 9733)
13.7
9.2
15
11
NBF25
NOMESCO Finland
Operation for humeroscapular osteochondritis, arthroscopic
2.8
9.1
46
170
SFA10
NOMESCO Finland
One-surface restoration
1.4
9.1
899
7637
SPAT1310
SPAT
Counselling related to known health issue
1.4
9.0
481
3696
SPAT1285
SPAT
Provision of consultation response
2.1
8.9
88
439
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
2.9
8.8
40
140
A02BC05
ATC
esomeprazole; systemic
1.4
8.7
655
5321
QX3HE, ,
SPAT
2.9
8.7
41
146
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.6
8.5
191
1225
NBR30
NOMESCO Finland
Extensive or radical excision of soft tissue tumour of shoulder or upper arm
90.5
8.4
9
*
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
2.1
8.4
81
401
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
8.3
774
6482
2152C
ICD-9 Finland
Other benign neoplasm of connective and other soft tissue, Upper limb, including shoulder[YLÄRAAJAN BENIGNI PEHMYTKUDOSKASVAIN,HERMOPERÄINEN]
+∞
8.3
8
*
N02BF01
ATC
gabapentin; oral
1.7
8.2
138
819
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
8.2
1085
9566
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
2.0
8.1
82
414
M65.3
ICD-10 Finland
Trigger finger
2.0
8.0
84
430
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.4
7.9
330
2418
M72.0
ICD-10 Finland
Palmar fascial fibromatosis [Dupuytren]
2.4
7.9
54
232
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.8
7.9
108
603
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
7.9
399
3028
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
2.5
7.9
48
196
M25.5
ICD-10 Finland
Pain in joint
1.4
7.8
524
4164
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.4
7.8
51
215
SPAT1202
SPAT
Intra-articular injection
2.4
7.7
50
210
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
7.7
651
5360
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
7.6
597
4860
H02AB06
ATC
prednisolone; systemic
1.3
7.5
750
6316
M54.2
ICD-10 Finland
Cervicalgia
1.7
7.5
134
809
M01AH01
ATC
celecoxib; oral
1.5
7.5
275
1966
A02BC01
ATC
omeprazole; systemic
1.4
7.5
412
3170
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.7
7.5
138
842
UJF32
NOMESCO Finland
Coloscopy
1.4
7.4
395
3020
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.6
7.4
24
68
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
2.7
7.3
37
138
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
3.4
7.3
25
74
WX290
NOMESCO Finland
Other blockage of nerve
1.3
7.2
755
6389
NC1DG
NOMESCO Finland
Elbow and forearm very extensive MRI examination with high intensity magnet
20.1
7.1
10
5
J01DA01
ATC
[U] cefalexin
1.3
7.1
1010
8910
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
2.1
7.0
63
304
NDK99
NOMESCO Finland
Other operation on bone of hand or wrist
10.1
7.0
13
13
ND1AA
NOMESCO Finland
Wrist X-ray examination
1.8
7.0
101
575
D21.6
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of trunk, unspecified
40.2
6.8
8
*
-1, ,
NOMESCO Finland
1.3
6.7
512
4136
G56.2
ICD-10 Finland
Lesion of ulnar nerve
2.1
6.7
60
290
M70.6
ICD-10 Finland
Trochanteric bursitis
1.5
6.7
205
1413
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.8
6.7
90
502
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
6.7
615
5103
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
6.6
167
1101
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
1.9
6.6
83
452
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
12.3
6.6
11
9
L17
ICPC
Foot/toe symptom/complaint
1.4
6.6
432
3411
NDF25
NOMESCO Finland
Operation for osteochondritis of joint of wrist, arthroscopic
4.2
6.6
17
41
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.5
942
8283
NBL05
NOMESCO Finland
Arthroscopic suture or reinsertation of rotator cuff of shoulder
3.0
6.5
27
90
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.6
6.5
132
827
KMAK, ,
NOMESCO Finland
1.3
6.5
828
7166
R51.80
ICD-10 Finland
Headache
1.5
6.4
237
1694
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
6.4
345
2637
J01CA04
ATC
amoxicillin; systemic
1.3
6.4
1348
12454
D48.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Peripheral nerves and autonomic nervous system
14.4
6.4
10
7
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
3.0
6.4
27
91
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.4
6.4
291
2163
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
2.9
6.4
29
102
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.8
6.4
96
554
T14.0
ICD-10 Finland
Superficial injury of unspecified body region
3.1
6.4
26
86
A54
ICPC
General and Unspecified, Repair/fix-suture/cast/prosth device
2.6
6.3
34
131
G56.4
ICD-10 Finland
Causalgia
6.0
6.3
16
27
WX402
NOMESCO Finland
General anaesthesia
1.4
6.3
325
2467
WX200
NOMESCO Finland
Interscalenous plexus blockade
2.5
6.3
39
161
D17
ICD-10 Finland
Benign lipomatous neoplasm
3.0
6.3
27
92
D17.9
ICD-10 Finland
Benign lipomatous neoplasm, unspecified
3.0
6.3
27
92
D16.0
ICD-10 Finland
Benign neoplasm: Scapula and long bones of upper limb
18.1
6.3
9
5
ND3CM
NOMESCO Finland
Extensive MRI of fingers (more than 1.5 T)
+∞
6.3
6
*
M19.2
ICD-10 Finland
Other secondary arthrosis
3.0
6.2
26
87
NDG76
NOMESCO Finland
Fusion of DIP joint
3.7
6.2
19
52
ND1BG, ,
SPAT
3.1
6.2
24
77
J01AA02
ATC
doxycycline; systemic
1.3
6.2
1290
11866
ENC40
NOMESCO Finland
Uvulopalatopharyngoplasty
3.2
6.2
23
72
S21
ICPC
Skin texture symptom/complaint
1.5
6.1
198
1378
TQW40, ,
SPAT
1.7
6.1
112
682
-, ,
ICD-10 Finland
2.4
6.1
39
163
D21.0
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of head, face and neck
7.7
6.1
13
17
R06AX27
ATC
desloratadine; oral
1.3
6.1
444
3555
J01DA09
ATC
[U] cefadroxil
1.3
6.1
411
3256
QCA99
NOMESCO Finland
Other local destruction of skin of upper limb
10.1
6.0
11
11
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
6.0
376
2941
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
6.0
148
971

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
81
307
2.72
15.14
6.0
10.3
11.13
11.30
mmol/l
0.17
75
280
81
307
2.72
15.14
6.0
10.3
105.43
105.40
mmol/l
0.01
75
280
774
6094
1.48
14.12
4.6
4.8
36.18
35.77
g/l
1.26
724
5693
1256
10903
1.52
13.90
4.8
4.0
11.41
11.78
mm/h
0.43
1170
10143
97
426
2.35
13.35
5.7
8.7
1.20
1.27
mmol/l
0.48
90
379
159
868
1.91
12.42
8.0
8.0
24.30
24.59
mmol/l
0.50
154
830
194
1142
1.78
11.92
4.0
3.4
—
—
—
0
0
793
6413
1.43
11.87
13.3
13.5
1.18
1.23
inr
0.93
239
1892
428
3081
1.51
11.70
4.5
3.9
1.02
1.02
kg/l
0.16
41
445
503
3774
1.46
11.11
4.5
3.8
0.00
0.01
estimate
1.28
174
1308
282
1896
1.58
10.39
1.3
1.3
—
—
—
0
0
1178
10380
1.40
9.87
4.0
3.6
—
—
—
0
0
356
2546
1.50
9.85
1.3
1.3
15.85
11.97
u/ml
0.38
155
1003
156
912
1.78
9.79
5.7
5.8
—
—
—
0
0
978
8410
1.36
9.19
4.5
4.9
6.58
6.68
mmol/l
0.90
912
7881
176
1090
1.68
8.99
2.8
2.7
131.97
189.01
ng/l
1.76
169
988
104
552
1.94
8.87
5.5
7.0
0.98
0.89
%
1.62
98
518
1575
14790
1.58
8.35
14.3
13.5
21.20
22.90
mg/l
1.21
1280
11667
725
6017
1.35
8.29
2.3
2.1
—
—
—
0
0
836
7115
1.33
7.95
4.0
3.5
0.00
0.00
estimate
0.50
177
1409
199
1313
1.58
7.88
6.8
9.5
122.88
121.60
g/l
0.37
194
1282
359
2676
1.43
7.86
3.4
3.5
339.49
414.16
ng/l
0.18
253
1996
101
557
1.86
7.70
5.6
6.9
2.06
1.60
%
2.84
95
524
811
6904
1.32
7.56
6.4
6.3
—
—
—
0
0
840
7191
1.32
7.51
4.0
3.5
0.00
0.01
estimate
1.08
168
1288
1629
15489
1.63
7.36
14.0
12.7
—
—
—
0
0
208
1411
1.54
7.29
6.5
9.1
96.41
95.73
%
1.09
201
1365
801
6851
1.31
7.05
2.5
2.5
—
—
—
0
0
354
2687
1.40
6.91
1.3
1.3
41.67
32.18
iu/ml
0.53
125
894
826
7124
1.30
6.72
4.8
4.8
0.01
0.00
estimate
0.41
174
1338
121
738
1.69
6.58
6.7
12.4
—
—
—
0
0
225
1588
1.48
6.51
6.4
8.5
4.99
5.11
kpa
1.07
217
1531
225
1588
1.48
6.51
6.3
8.5
12.23
12.42
kpa
0.21
217
1531
524
4272
1.32
6.38
2.1
2.1
171.18
217.69
u/l
0.86
497
4034
223
1582
1.47
6.29
6.4
8.5
1.25
1.16
mmol/l
0.14
169
1264
1595
15188
1.49
6.08
15.8
15.4
3.97
3.96
mmol/l
0.24
1565
14806
1590
15141
1.48
5.95
15.7
15.3
139.83
139.69
mmol/l
1.75
1562
14780
1704
16501
1.82
5.82
21.3
19.9
40.51
40.26
%
0.91
1547
15508
1706
16528
1.83
5.79
21.3
19.9
136.12
135.82
g/l
0.37
1693
16313
1704
16519
1.79
5.53
21.2
19.7
90.73
90.93
fl
1.09
1691
16310
1047
9437
1.27
5.51
4.5
4.2
3128.69
2200.92
e6/l
0.12
16
134
1704
16521
1.79
5.50
21.3
19.8
6.57
6.68
e9/l
1.10
1678
16103
1704
16522
1.78
5.49
21.2
19.7
30.30
30.30
pg
0.00
1691
16311
1703
16510
1.78
5.48
21.3
19.8
256.50
253.44
e9/l
1.25
1683
16138
1704
16523
1.78
5.47
21.3
19.8
4.52
4.51
e12/l
0.61
1681
16104
32
133
2.43
5.14
1.6
1.4
23.25
32.08
%
0.69
12
82
1359
12704
1.30
5.04
19.1
17.1
333.19
332.56
g/l
1.79
1354
12616
1376
12885
1.30
5.03
15.8
16.0
14.38
14.86
%
3.21
1353
12654
801
7060
1.25
4.88
6.6
6.8
1.21
1.21
mmol/l
0.05
679
6040
542
4574
1.27
4.82
2.6
2.5
56.46
76.80
u/l
0.61
510
4251
462
3826
1.28
4.79
2.7
2.6
2248.05
5096.16
umol/l
1.20
405
3371
825
7326
1.24
4.60
6.2
5.9
0.04
0.04
e9/l
0.54
758
6405
823
7310
1.23
4.57
6.2
5.9
0.56
0.57
e9/l
0.81
755
6388
263
2037
1.34
4.43
1.8
2.1
—
—
—
0
0
296
3696
0.76
4.38
3.3
3.8
91.74
92.19
%
0.12
285
3597
1086
9971
1.23
4.26
4.6
4.2
—
—
—
0
0
847
7584
1.22
4.24
6.2
6.1
0.20
0.19
e9/l
0.86
786
6714
6
236
0.25
4.19
7.8
5.9
378.67
363.95
umol/l
—
6
212
395
3260
1.27
4.15
4.4
3.5
—
—
—
0
0
1216
11326
1.23
4.04
7.9
7.5
75.45
77.20
u/l
0.68
1163
10717
653
5720
1.22
3.99
3.8
3.3
5.87
5.82
ph
0.12
42
476
14
43
3.27
3.91
1.3
1.2
53.56
48.92
%
—
9
38
835
7512
1.21
3.85
6.2
5.9
1.86
1.96
e9/l
1.26
779
6718
1432
13618
1.27
3.75
5.0
4.8
1.82
2.09
mu/l
1.09
1342
12570
22
90
2.46
3.72
5.5
6.5
—
—
—
0
0
1429
13599
1.26
3.64
5.6
5.5
39.07
39.58
mmol/mol
1.58
1351
12671
88
580
1.54
3.61
1.4
1.2
0.94
1.01
u/ml
—
7
45
1222
11446
1.22
3.57
4.4
4.1
14.76
14.72
pmol/l
0.27
1145
10519
487
4183
1.23
3.52
4.0
4.0
7.40
7.40
ph
0.08
85
796
611
5379
1.21
3.43
3.3
3.4
24.96
57.17
ng/l
2.27
372
3558
29
140
2.09
3.38
4.0
4.8
31.99
44.70
u/ml
—
9
42
214
1678
1.31
3.32
1.8
1.7
—
—
—
0
0
926
8488
1.19
3.29
9.0
9.2
4.00
4.04
e9/l
0.19
849
7479
714
6400
1.19
3.26
5.8
6.0
1.21
1.21
mmol/l
0.16
657
5867
1628
15804
1.36
3.24
11.2
10.2
26.90
26.59
u/l
0.24
1592
15320
142
1052
1.38
3.21
1.4
1.4
—
—
—
0
0
102
714
1.45
3.17
2.4
2.4
—
—
—
0
0
1536
14803
1.28
3.14
4.7
4.3
4.70
4.74
mmol/l
0.85
1464
13836
834
7609
1.18
3.04
5.8
6.2
10.63
11.11
umol/l
0.73
793
7256
464
4021
1.21
3.02
1.8
1.7
1.39
1.39
mmol/l
0.01
399
3407
22
101
2.19
2.93
1.2
1.1
—
—
—
0
0
483
4213
1.20
2.92
2.9
2.9
—
—
—
0
0
1555
15038
1.27
2.88
5.1
4.8
2.80
2.82
mmol/l
0.37
1474
13977
174
2208
0.77
2.86
3.0
2.8
4.18
2.65
e6/l
0.63
93
1197
474
4137
1.20
2.84
3.3
3.3
768.54
404.40
mg/l
0.55
291
2617
80
547
1.48
2.83
6.2
4.5
—
—
—
0
0
48
295
1.64
2.70
2.7
3.9
58.77
57.38
%
0.29
48
295
124
928
1.36
2.67
3.3
3.3
4.49
4.49
pmol/l
0.00
114
813
159
1236
1.31
2.66
4.6
4.2
1.00
1.02
%
0.02
50
438
46
282
1.65
2.62
2.6
3.6
4.56
4.14
e9/l
0.32
46
282
344
2934
1.21
2.61
2.4
2.5
5.25
6.00
e6/l
0.54
317
2646
402
3485
1.20
2.57
2.4
2.1
2.73
2.97
mg/l
1.41
362
2979
64
427
1.52
2.57
1.1
1.1
23.20
5.36
u/ml
—
8
52
8
20
4.01
2.57
1.4
1.5
—
—
—
0
0
555
4951
1.18
2.55
3.3
3.2
32.58
31.83
u/l
0.11
525
4713
11
273
0.40
2.54
2.8
2.9
7.95
7.36
mmol/l
0.32
11
265
63
423
1.51
2.47
5.6
4.0
3.93
3.85
mmol/l
0.56
63
418
246
2042
1.24
2.43
1.4
1.3
588.18
530.54
titre
0.21
44
425
665
6036
1.16
2.43
2.5
2.3
77.61
77.03
nmol/l
0.23
609
5467
142
1102
1.31
2.42
4.9
4.3
0.03
0.66
%
0.97
31
303
424
3712
1.19
2.42
3.6
4.3
—
—
—
0
0
40
639
0.62
2.41
3.5
3.6
—
—
—
0
0
13
292
0.44
2.37
2.5
2.8
1.46
1.54
mmol/l
0.25
13
281
39
237
1.66
2.33
1.5
1.4
—
—
—
0
0
489
4358
1.17
2.24
3.8
3.8
8.85
8.74
mg/mmol
0.02
300
2719
77
550
1.42
2.23
2.2
2.1
1.84
1.81
ug/l
0.02
70
495
20
100
2.01
2.21
1.4
1.0
—
—
—
0
0
540
4855
1.16
2.20
3.2
3.4
2.35
2.35
mmol/l
0.27
485
4323
431
3808
1.17
2.19
2.7
2.9
1133.00
1141.28
ng/l
0.02
379
3204
247
2077
1.22
2.17
1.3
1.2
—
—
—
0
0
1517
14719
1.21
2.15
4.5
4.3
1.46
1.48
mmol/l
1.09
1437
13674
692
6344
1.15
2.14
3.1
2.8
111.11
122.40
ug/l
0.82
660
5899
444
3940
1.17
2.14
3.2
3.2
—
—
—
0
0
153
1223
1.27
2.11
4.0
3.7
—
—
—
0
0
298
2566
1.19
2.05
2.5
3.0
2.45
2.45
mmol/l
0.13
269
2260
141
1122
1.28
2.03
4.6
4.0
0.95
0.70
%
0.24
40
371
12
259
0.46
2.01
1.3
1.5
—
—
—
0
0
6
163
0.37
2.01
2.5
2.3
—
—
—
0
0
70
505
1.40
1.95
5.2
3.9
1.26
1.37
mmol/l
0.41
70
495
26
149
1.76
1.95
2.3
2.1
—
—
—
0
0
63
872
0.71
1.91
3.0
3.5
5.12
5.16
kpa
0.18
63
842
12
253
0.47
1.90
1.2
1.4
—
—
—
0
0
12
251
0.47
1.86
1.2
1.4
—
—
—
0
0
1480
14369
1.18
1.86
4.6
4.4
5.86
5.91
mmol/l
0.71
1392
13190
51
351
1.47
1.84
1.8
1.7
5726.83
12237.33
e6/l
1.80
36
258
26
428
0.60
1.83
3.0
3.2
—
—
—
0
0
106
825
1.30
1.83
1.3
1.2
—
—
—
0
0
305
3480
0.85
1.82
2.2
2.3
—
—
—
0
0
63
862
0.72
1.80
3.0
3.5
7.43
7.41
ph
—
10
110
61
437
1.41
1.79
2.9
2.2
5464.93
2930.54
u/l
0.31
23
176
20
350
0.57
1.78
5.2
4.2
—
—
—
0
0
144
1173
1.25
1.74
4.9
4.3
0.03
0.14
%
2.57
35
374
489
4433
1.14
1.73
3.2
3.2
7.80
7.53
mmol/l
0.62
419
3777
10
216
0.46
1.71
2.8
2.4
—
—
—
0
0
113
1411
0.79
1.70
4.0
4.1
—
—
—
0
0
367
3273
1.15
1.64
1.3
1.2
2.17
1.39
u/ml
0.48
127
877
30
189
1.60
1.63
1.7
1.5
62.22
58.98
%
—
9
121
35
230
1.53
1.60
1.4
1.2
—
—
—
0
0
246
2822
0.85
1.57
2.9
2.8
520.39
537.87
mosm/kgh2o
0.64
214
2446
16
85
1.89
1.55
2.3
1.7
18.54
8.91
ug/l
0.45
16
70
24
145
1.66
1.54
1.4
1.3
4171.33
86809.32
e6/l
1.05
15
99
0
42
0.00
1.52
0.0
1.0
—
—
—
0
0
14
72
1.95
1.49
1.2
1.4
—
—
—
0
0
14
72
1.95
1.49
1.0
1.3
244.21
421.30
u/l
0.58
14
66
356
3197
1.14
1.44
1.6
1.5
20.27
20.88
nmol/l
0.36
307
2734
72
554
1.31
1.41
1.1
1.1
—
—
—
0
0
10
46
2.18
1.40
1.9
2.1
—
—
—
0
0
376
4142
0.88
1.36
3.7
3.6
—
—
—
0
0
33
223
1.49
1.36
1.3
1.7
0.50
0.86
g/l
1.51
20
171
22
135
1.64
1.36
1.2
1.4
2.89
2.82
g/l
0.06
14
93
22
135
1.64
1.36
1.2
1.4
8.78
6.99
g/l
0.33
14
94
22
135
1.64
1.36
1.2
1.4
0.44
0.36
g/l
0.36
14
94
5
17
2.95
1.36
1.6
1.2
151.80
88.84
ng/l
—
5
17
15
83
1.81
1.31
1.1
1.1
1.07
1.05
ratio
—
5
34
14
244
0.57
1.29
1.1
1.2
2.80
5.22
u/ml
—
5
100
18
106
1.71
1.29
1.6
1.4
84.56
78.72
umol/l
0.28
18
106
329
2963
1.14
1.28
1.6
1.7
31734736.50
35654011.12
pmol/l
0.04
271
2471
421
4586
0.89
1.26
2.2
2.3
—
—
—
0
0
8
159
0.50
1.24
1.0
1.1
—
—
—
0
0
22
139
1.59
1.23
1.2
1.4
—
—
—
0
0
15
85
1.77
1.23
1.0
1.0
—
—
—
0
0
245
2172
1.15
1.21
1.6
2.0
29.36
29.66
s
0.30
235
2108
258
2299
1.14
1.19
2.7
3.4
0.84
0.82
mmol/l
1.50
250
2171
37
509
0.72
1.17
2.7
3.6
0.20
0.27
g/l
0.53
14
219
72
900
0.79
1.16
1.4
1.7
—
—
—
0
0
192
1686
1.16
1.10
1.5
1.7
—
—
—
0
0
5
21
2.38
1.09
2.2
1.7
—
—
—
0
0
14
81
1.73
1.09
1.0
1.0
—
—
—
0
0
9
162
0.55
1.08
1.0
1.2
—
—
—
0
0
105
878
1.21
1.07
7.7
10.1
93.76
93.92
%
0.10
105
871
49
374
1.32
1.07
3.0
2.3
—
—
—
0
0
32
228
1.41
1.06
1.1
1.0
6.42
2.15
u/ml
1.01
16
103
13
75
1.74
1.02
1.2
1.3
—
—
—
0
0
115
975
1.19
1.02
1.4
1.2
164.04
201.50
u/ml
0.41
110
899
202
1792
1.14
1.02
2.8
2.3
161.50
121.15
ug/g
0.67
167
1437
42
551
0.76
1.01
1.2
2.0
21.93
21.53
s
0.11
30
490
165
1445
1.16
1.00
1.4
1.4
—
—
—
0
0
52
405
1.29
0.99
1.6
1.8
41.90
38.32
nmol/l
0.45
52
392
18
115
1.57
0.99
1.2
1.5
1.60
1.22
promille
0.41
13
90
148
1286
1.16
0.99
1.4
1.4
—
—
—
0
0
401
3712
1.10
0.98
6.3
6.7
—
—
—
0
0
110
936
1.19
0.95
1.3
1.3
61.94
44.49
au/ml
—
8
59
35
259
1.36
0.95
3.0
2.9
—
—
—
0
0
14
85
1.65
0.94
1.3
1.3
143.93
140.48
nmol/l
0.08
14
85
84
1005
0.83
0.94
1.6
1.4
—
—
—
0
0
10
172
0.58
0.93
1.9
2.5
—
—
—
0
0
8
146
0.55
0.92
3.3
3.3
—
—
—
0
0
433
4036
1.10
0.92
4.9
4.6
2.09
2.31
ug/l
0.57
402
3623
1448
14204
1.11
0.90
4.1
3.9
1.32
1.31
mmol/l
0.30
1368
13132
185
1650
1.14
0.88
1.6
1.6
—
—
—
0
0
10
169
0.59
0.88
1.2
1.1
—
—
—
0
0
699
6662
1.08
0.88
6.2
6.0
0.72
0.68
%
1.30
667
6246
20
288
0.69
0.87
1.3
1.2
296.85
258.79
u/ml
0.26
13
171
8
43
1.86
0.87
1.3
1.0
—
—
—
0
0
95
806
1.19
0.87
3.0
3.2
215.38
48.73
u/ml
0.61
90
780
79
659
1.21
0.87
1.8
1.8
—
—
—
0
0
720
6874
1.08
0.86
6.1
6.0
2.96
2.82
%
0.87
690
6452
32
238
1.35
0.86
1.1
1.2
—
—
—
0
0
239
2172
1.12
0.84
2.6
2.4
13.05
13.51
umol/l
0.43
224
2019
102
875
1.18
0.83
7.8
10.0
0.72
0.69
%
0.38
102
868
6
115
0.52
0.82
1.0
1.1
—
—
—
0
0
130
1140
1.15
0.81
3.3
2.8
10.24
10.58
g/l
0.36
117
1041
41
520
0.78
0.80
2.8
3.5
53.60
2748.46
u/ml
0.79
30
445
30
224
1.35
0.80
1.2
1.2
—
—
—
0
0
0
24
0.00
0.79
0.0
3.9
—
44.09
—
0
17
0
25
0.00
0.79
0.0
1.1
—
—
—
0
0
0
25
0.00
0.79
0.0
1.1
—
—
—
0
0
8
48
1.67
0.78
1.0
1.5
49.50
87.50
nmol/24h
—
8
48
11
66
1.67
0.78
2.2
2.4
35.66
49.74
umol/l
1.15
11
55
102
881
1.17
0.78
7.8
9.9
1.48
1.36
%
0.87
102
874
721
6913
1.07
0.75
6.3
6.3
8.52
8.51
%
0.01
693
6496
1040
10102
1.07
0.74
3.2
3.1
47.20
47.23
u/l
0.00
983
9483
117
1026
1.15
0.74
2.4
2.4
23.42
25.56
au/ml
0.09
12
81
26
345
0.75
0.73
1.9
2.7
24.73
24.82
mmol/l
0.04
26
340
55
452
1.22
0.73
1.5
1.3
255.86
219.68
miu/ml
0.24
21
215
5
25
2.00
0.72
6.0
7.8
—
—
—
0
0
14
92
1.53
0.72
1.7
1.5
—
—
—
0
0
124
1095
1.14
0.72
4.0
3.7
94.59
83.37
ng/l
0.64
111
957
117
1030
1.15
0.71
1.6
2.8
6.50
5.74
e9/l
0.10
104
851
132
1175
1.13
0.69
1.1
1.2
—
—
—
0
0
5
27
1.85
0.68
1.0
1.1
89.92
69.21
ug/l
—
5
22
5
27
1.85
0.68
1.4
2.2
—
—
—
0
0
50
605
0.82
0.68
1.4
2.0
1.51
1.55
g/l
0.13
44
526
72
613
1.18
0.67
1.3
1.2
—
—
—
0
0
32
250
1.29
0.66
1.2
1.7
—
—
—
0
0
11
71
1.55
0.62
1.4
1.2
—
—
—
0
0
28
217
1.29
0.62
2.5
2.7
—
—
—
0
0
5
30
1.67
0.61
1.0
1.1
0.17
2.40
u/ml
—
5
24
30
235
1.28
0.61
1.4
1.5
—
—
—
0
0
128
1148
1.12
0.61
2.3
2.3
4.90
7.44
ug/l
1.62
120
1026
0
20
0.00
0.60
0.0
5.9
—
—
—
0
0
37
455
0.81
0.60
1.1
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
2.1
—
3.46
—
0
7
23
174
1.33
0.60
1.8
1.6
—
—
—
0
0
0
22
0.00
0.59
0.0
1.4
—
—
—
0
0
166
1514
1.11
0.59
1.4
1.4
—
—
—
0
0
226
2097
1.09
0.57
1.5
1.6
—
—
—
0
0
30
238
1.26
0.57
1.3
1.2
—
—
—
0
0
735
7107
1.06
0.56
6.2
6.0
28.55
28.23
%
0.35
706
6699
13
183
0.71
0.55
1.2
1.2
—
—
—
0
0
49
414
1.19
0.53
1.1
1.1
—
—
—
0
0
9
62
1.45
0.53
1.7
2.2
33.63
151.04
ug/l
—
9
52
21
271
0.77
0.52
1.2
1.6
—
—
—
0
0
58
499
1.17
0.52
1.6
1.9
—
—
—
0
0
25
314
0.79
0.51
1.1
2.2
0.91
0.86
nmol/l
0.17
18
267
11
75
1.47
0.50
1.2
1.4
—
—
—
0
0
14
101
1.39
0.49
1.3
1.3
1.53
1.57
g/l
0.15
14
101
58
502
1.16
0.49
1.6
1.9
—
—
—
0
0
13
93
1.40
0.48
1.4
1.4
186.27
162.65
pmol/l
0.34
13
93
58
503
1.16
0.48
1.6
1.9
—
—
—
0
0
202
1883
1.08
0.47
5.0
5.7
1.03
1.03
mmol/l
0.10
186
1742
7
47
1.49
0.47
1.0
1.1
—
—
—
0
0
149
1371
1.09
0.47
1.8
2.3
0.21
0.22
g/l
0.17
125
1284
671
6503
1.05
0.46
9.1
9.3
0.00
0.00
e9/l
0.63
590
5366
583
5630
1.05
0.46
2.7
2.8
—
—
—
0
0
224
2387
0.93
0.46
3.1
2.9
0.77
0.75
ug/l
0.12
134
1488
58
506
1.15
0.45
1.6
1.9
—
—
—
0
0
55
478
1.16
0.45
11.1
9.7
—
—
—
0
0
7
50
1.40
0.45
1.4
1.9
41.47
50.15
ug/l
—
7
50
41
348
1.18
0.44
1.9
2.3
122.82
113.66
ug/min
0.05
23
211
191
1783
1.08
0.44
1.2
1.4
—
—
—
0
0
32
383
0.83
0.44
2.0
1.9
2.99
4.96
iu/l
1.76
13
129
37
312
1.19
0.43
1.4
1.8
—
—
—
0
0
9
127
0.71
0.43
2.4
2.0
44.93
38.51
%
—
9
127
13
174
0.75
0.43
1.2
1.2
—
—
—
0
0
5
31
1.61
0.43
1.6
1.3
—
—
—
0
0
5
32
1.56
0.42
6.0
7.1
—
—
—
0
0
387
4037
0.95
0.42
1.4
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
2.1
—
37.13
—
0
15
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
28
337
0.83
0.41
1.9
2.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
115
1055
1.10
0.41
1.2
1.2
115.40
142.05
iu/ml
0.38
48
406
5
34
1.47
0.40
1.2
1.1
—
—
—
0
0
5
34
1.47
0.40
1.2
1.1
—
—
—
0
0
5
34
1.47
0.40
1.2
1.1
—
—
—
0
0
117
1075
1.09
0.40
1.4
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
122.61
—
0
7
149
1385
1.08
0.40
2.0
2.2
360.94
367.52
nmol/l
0.17
131
1277
47
409
1.15
0.39
1.1
1.3
—
1094.17
—
0
12
179
1678
1.07
0.39
1.5
1.3
—
—
—
0
0
32
270
1.19
0.38
1.7
1.6
—
—
—
0
0
51
448
1.14
0.38
1.1
1.2
—
—
—
0
0
32
271
1.18
0.37
1.2
1.2
—
—
—
0
0
32
374
0.85
0.35
1.4
1.3
—
—
—
0
0
5
76
0.66
0.35
2.8
2.8
37620.00
38874.32
ug/l
—
5
76
718
7010
1.04
0.35
6.1
5.8
56.51
56.96
%
0.49
693
6597
9
126
0.71
0.35
1.4
1.3
—
—
—
0
0
212
2012
1.06
0.33
2.7
2.4
2.44
2.34
g/l
1.60
198
1863
64
706
0.90
0.32
3.3
3.3
—
—
—
0
0
7
52
1.35
0.31
2.0
1.3
—
—
—
0
0
25
294
0.85
0.31
1.2
1.3
—
—
—
0
0
12
153
0.78
0.30
2.3
2.7
—
—
—
0
0
44
391
1.13
0.30
1.4
1.4
6.78
10.09
u/l
1.70
39
316
14
174
0.80
0.29
1.3
1.4
—
—
—
0
0
399
3865
1.04
0.29
3.0
3.0
0.44
0.46
e6/l
0.05
326
2948
25
213
1.18
0.29
1.1
1.3
—
0.41
nmol/l
—
0
17
33
288
1.15
0.29
1.6
2.0
4.41
5.26
mmol/24h
0.93
28
252
277
2879
0.96
0.28
1.6
1.5
2.40
2.42
g/l
0.04
185
1800
33
289
1.14
0.28
3.2
3.6
—
—
—
0
0
45
501
0.90
0.27
2.5
2.6
—
—
—
0
0
8
64
1.25
0.27
1.0
1.2
537.38
244.09
iu/ml
—
8
64
5
73
0.68
0.26
1.4
2.9
—
—
—
0
0
5
75
0.67
0.25
3.0
3.0
370.40
1321.76
u/ml
—
5
75
15
123
1.22
0.25
1.3
1.5
1.04
0.98
g/l
0.31
15
123
97
908
1.07
0.25
2.1
1.8
1.37
1.42
g/l
0.07
87
837
13
159
0.82
0.24
1.4
1.5
—
—
—
0
0
164
1564
1.05
0.24
1.3
1.4
—
—
—
0
0
9
77
1.17
0.24
1.1
1.5
—
70.40
%
—
0
10
30
265
1.13
0.23
1.0
1.1
—
—
—
0
0
412
4227
0.97
0.23
3.2
3.1
290.64
69.22
e6/l
0.40
337
3264
27
306
0.88
0.23
1.4
1.4
—
—
—
0
0
11
88
1.25
0.22
1.2
1.9
—
—
—
0
0
5
40
1.25
0.22
1.0
1.3
26.60
74.61
mu/l
—
5
31
5
40
1.25
0.22
1.6
1.6
—
—
—
0
0
7
94
0.74
0.22
3.1
3.7
—
—
—
0
0
114
1203
0.94
0.22
1.7
1.6
—
—
—
0
0
115
1090
1.06
0.22
2.2
2.9
67.56
70.95
e9/l
0.54
92
845
24
210
1.14
0.21
1.4
2.3
—
4.17
—
0
6
5
42
1.19
0.21
1.0
1.2
195.20
322.21
pmol/l
—
5
29
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
27
239
1.13
0.21
1.0
1.1
0.46
1.55
u/ml
—
10
101
195
1877
1.04
0.21
2.7
2.5
22.03
23.48
%
0.71
159
1597
0
13
0.00
0.21
0.0
6.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
173.20
—
0
5
11
134
0.82
0.20
1.5
1.4
—
—
—
0
0
109
1148
0.95
0.20
3.0
2.9
67.19
66.78
g/l
0.25
102
1049
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
20
229
0.87
0.20
1.1
1.0
0.61
1.83
u/ml
—
8
115
28
250
1.12
0.19
1.0
1.1
4.47
4.40
u/ml
0.01
12
129
254
2463
1.04
0.19
1.8
1.7
1339.18
1195.30
nmol/l
1.85
206
1880
11
90
1.22
0.19
1.5
1.4
4.91
7.76
u/l
0.80
11
73
109
1145
0.95
0.19
6.9
8.9
—
—
—
0
0
6
52
1.15
0.19
1.3
1.3
158.83
139.29
nmol/l
—
6
40
131
1369
0.95
0.19
2.2
2.4
137.94
73.57
u/l
0.25
110
1186
106
1010
1.05
0.18
2.1
2.2
13.20
13.01
nmol/l
0.09
97
911
17
195
0.87
0.17
1.0
1.0
8.36
2.78
u/ml
—
6
89
37
403
0.92
0.17
1.1
1.2
—
—
—
0
0
38
413
0.92
0.17
1.8
1.5
287.00
286.99
ug/g
0.00
23
245
99
945
1.05
0.16
3.2
2.7
—
—
—
0
0
36
391
0.92
0.16
1.8
1.8
—
—
—
0
0
8
71
1.13
0.16
2.1
1.2
—
—
—
0
0
21
187
1.12
0.16
1.1
1.3
—
—
nmol/l
—
0
0
341
3338
1.03
0.15
1.6
1.7
0.98
1.08
mg/l
0.36
268
2531
6
78
0.77
0.15
1.3
2.8
—
—
—
0
0
22
197
1.12
0.15
1.1
1.3
—
—
—
0
0
9
80
1.13
0.15
1.3
1.3
36.73
24.03
umol/l
—
9
74
21
188
1.12
0.14
3.4
2.4
—
—
—
0
0
161
1662
0.97
0.14
2.8
2.8
7.18
7.83
umol/l
0.23
142
1460
7
90
0.78
0.14
14.7
12.1
0.58
0.64
mmol/l
—
7
83
10
118
0.85
0.14
1.4
1.2
0.24
0.81
u/ml
—
5
62
29
266
1.09
0.14
1.0
1.1
—
—
—
0
0
13
149
0.87
0.13
2.8
2.3
—
—
—
0
0
27
247
1.09
0.13
1.1
1.1
—
—
—
0
0
67
637
1.05
0.13
2.6
2.4
1.36
1.22
%
0.41
67
632
229
2343
0.97
0.12
2.6
2.6
1.30
1.10
e6/l
0.39
143
1330
489
4958
0.98
0.12
3.6
3.6
65.63
82.31
e6/l
0.34
380
3499
10
116
0.86
0.12
1.0
1.4
—
—
—
0
0
13
114
1.14
0.11
1.6
1.5
18.73
12.64
umol/l
0.76
13
108
11
126
0.87
0.11
1.1
1.2
—
—
—
0
0
10
115
0.87
0.10
2.3
2.3
798.00
612.05
ml
—
5
76
22
239
0.92
0.10
2.0
2.5
—
—
—
0
0
13
146
0.89
0.10
1.1
1.1
—
—
—
0
0
29
271
1.07
0.09
1.0
1.1
0.39
2.18
u/ml
2.39
11
141
16
145
1.10
0.09
1.3
1.1
—
—
—
0
0
29
309
0.94
0.09
2.9
3.8
33.61
24.36
mg/l
0.55
19
190
11
97
1.13
0.09
2.5
2.1
—
—
—
0
0
26
278
0.93
0.09
1.5
1.4
107.00
107.54
u/ml
—
8
55
6
54
1.11
0.09
1.0
1.6
—
—
—
0
0
6
56
1.07
0.08
2.3
1.9
—
—
—
0
0
10
113
0.88
0.08
1.4
1.1
—
—
—
0
0
5
63
0.79
0.08
2.2
2.8
—
—
—
0
0
83
805
1.03
0.08
6.4
7.8
25.19
24.97
mmol/l
0.19
83
799
20
185
1.08
0.08
2.8
2.3
—
—
—
0
0
17
156
1.09
0.08
3.1
4.0
—
—
—
0
0
14
127
1.10
0.08
1.6
1.3
38474.88
122249.51
e6/l
—
8
67
7
68
1.03
0.07
1.7
1.1
674.29
1711.12
miu/ml
—
7
68
98
955
1.03
0.07
1.3
1.2
—
—
—
0
0
30
284
1.06
0.07
2.5
2.7
—
—
—
0
0
94
964
0.97
0.07
3.0
2.6
—
—
—
0
0
7
82
0.85
0.07
2.3
2.1
2.19
3.31
ug/l
—
7
75
14
153
0.91
0.07
2.2
2.7
0.76
1.66
g/24h
—
6
81
45
432
1.04
0.07
5.0
3.9
44.66
61.67
mg/l
0.47
40
349
571
5668
1.01
0.07
2.1
1.9
94.36
96.07
pmol/l
0.42
282
2956
85
828
1.03
0.07
2.9
3.0
122.39
129.31
g/l
1.93
80
810
383
3793
1.01
0.06
2.9
3.0
—
—
—
0
0
33
315
1.05
0.06
5.1
4.1
8.37
8.64
kpa
0.42
33
310
12
109
1.10
0.06
2.1
1.7
10.60
10.80
%
0.06
12
109
26
247
1.05
0.05
1.4
1.5
—
—
—
0
0
256
2535
1.01
0.05
1.7
1.7
—
—
—
0
0
26
248
1.05
0.05
1.4
1.2
13.65
38.01
u/l
1.91
21
211
116
1142
1.02
0.04
4.8
3.8
1.24
1.23
mmol/l
1.13
99
991
16
150
1.07
0.04
1.7
1.6
—
—
—
0
0
10
91
1.10
0.04
1.9
2.1
464.20
500.83
min
—
5
65
15
160
0.94
0.04
1.2
1.4
—
—
—
0
0
39
379
1.03
0.03
4.6
3.8
7.42
7.42
ph
0.07
39
335
28
290
0.96
0.03
1.9
2.6
8.09
8.12
kpa
0.04
28
284
19
181
1.05
0.03
1.1
1.1
1.00
3.40
u/ml
—
5
69
22
211
1.04
0.03
1.7
1.8
1.49
1.68
mmol/l
0.60
22
206
55
561
0.98
0.03
1.7
1.6
—
—
—
0
0
122
1233
0.99
0.02
3.3
3.5
1.76
1.96
mmol/l
0.29
102
1023
42
411
1.02
0.02
2.1
3.1
1.43
1.51
mg/l
0.35
37
383
23
238
0.97
0.02
1.0
1.1
—
—
—
0
0
29
298
0.97
0.02
2.1
2.2
130.63
130.22
g/l
0.03
24
222
31
318
0.97
0.02
1.2
1.4
—
—
—
0
0
68
689
0.99
0.01
1.0
1.1
—
—
—
0
0
142
1427
0.99
0.00
3.5
4.2
61.63
19.11
ug/l
0.33
121
1165
32
314
1.02
0.00
5.2
4.1
2.86
2.76
mmol/l
0.07
24
214
33
324
1.02
0.00
6.0
4.0
—
—
—
0
0
40
406
0.98
0.00
1.4
1.2
4.03
11.58
u/ml
—
7
70
19
195
0.97
0.00
1.4
1.8
—
—
—
0
0
11
111
0.99
0.00
1.4
1.3
—
—
—
0
0
14
139
1.01
0.00
1.0
1.3
—
—
—
0
0
15
149
1.01
0.00
1.2
1.2
—
—
—
0
0
32
315
1.02
0.00
5.2
4.1
4.90
5.06
kpa
0.49
32
310
24
244
0.98
0.00
1.3
1.3
68.41
60.85
mmol/l
0.42
17
202
28
276
1.01
0.00
2.2
2.4
16.84
16.26
%
0.37
13
139
42
424
0.99
0.00
4.1
3.8
1.34
1.82
ratio
—
6
35
124
1242
1.00
0.00
3.3
3.4
5.73
5.84
kpa
0.65
119
1207
19
193
0.98
0.00
1.4
2.0
—
1506.67
—
0
6
148
1477
1.00
0.00
2.1
2.7
1.71
1.79
%
0.53
126
1320
7
70
1.00
0.00
1.3
1.3
149.71
171.04
mmol/24h
—
7
70
8
86
0.93
-0.00
1.0
1.1
—
11.48
—
0
24
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
69
0.87
-0.00
1.0
1.8
—
—
—
0
0
5
57
0.88
-0.00
2.0
2.5
—
—
—
0
0
8
88
0.91
-0.00
1.4
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
2.2
2.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
1.83
—
0
9
0
8
0.00
-0.00
0.0
1.6
—
16.86
—
0
8
38
380
1.00
-0.00
1.1
1.2
—
5.38
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
-0.00
10.2
2.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
77
0.91
-0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
46
460
1.00
-0.00
1.7
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
8
87
0.92
-0.00
1.4
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
-0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
13
130
1.00
-0.00
1.2
1.1
—
—
—
0
0
7
79
0.89
-0.00
2.9
2.1
1.46
2.10
ug/l
—
7
68
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
2.38
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
11.0
11.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_CONNSOFT_UPPERLIMB and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_CONNSOFT_UPPERLIMB 0.94 [0.82, 1.08] 0.387
Birth year 0.99 [0.98, 1.0] 0.028

During the follow-up period (1.1.1998 — 31.12.2019), 318 out of 4348 females with CD2_BENIGN_CONNSOFT_UPPERLIMB died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_CONNSOFT_UPPERLIMB 0.861 [0.75, 0.99] 0.039
Birth year 0.99 [0.98, 1.0] 0.028

During the follow-up period (1.1.1998 — 31.12.2019), 344 out of 3643 males with CD2_BENIGN_CONNSOFT_UPPERLIMB died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_CONNSOFT_UPPERLIMB.

N-year risk Females Males
1 0.063% 0.184%
5 0.461% 1.067%
10 1.17% 2.703%
15 2.402% 5.095%
20 4.083% 8.63%

Relationships between endpoints

Index endpoint: CD2_BENIGN_CONNSOFT_UPPERLIMB – Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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