Risteys · I9_SAHANEUR

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters None 0 out of 7 registries used, show all original rules.	0
4. Check minimum number of events None	0
5. Include endpoints I9_ANEUR I9_ANEURYSM I9_SAH	7026
6. Filter based on genotype QC (FinnGen only)	7026

	All	Female	Male
Number of individuals
Whole population	62174	32691	28490
Only index persons	40631	22510	18121
Unadjusted period prevalence (%)
Whole population	0.87	0.94	0.80
Only index persons	0.77	0.83	0.69
Median age at first event (years)
Whole population	57.71	59.42	55.75
Only index persons	57.42	58.55	56.02

	All	Female	Male
Number of individuals	7026	3992	3034
Unadjusted period prevalence (%)	1.35	1.36	1.34
Median age at first event (years)	56.92	56.29	57.75

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
6415: Matched controls
64150

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

I60.0

ICD-10 Finland

Subarachnoid haemorrhage from carotid siphon and bifurcation

+∞

323.0

430

PA2LT

NOMESCO Finland

Endovascular closure of extensive brain aneurysm

2141.2

323.0

422

I69.0

ICD-10 Finland

Sequelae of subarachnoid haemorrhage

6118.2

323.0

1052

I60.2

ICD-10 Finland

Subarachnoid haemorrhage from anterior communicating artery

+∞

323.0

563

I63.9

ICD-10 Finland

Cerebral infarction, unspecified

129.6

323.0

922

2161

FHL

Neck ligation, big brain

+∞

323.0

429

AAC00

NOMESCO Finland

Ligature of intracranial aneurysm

+∞

323.0

1568

AAL00

NOMESCO Finland

Endovascular occlusion of intracranial aneurysm

+∞

323.0

316

I60.9

ICD-10 Finland

Subarachnoid haemorrhage, unspecified

4079.5

323.0

1855

I63.3

ICD-10 Finland

Cerebral infarction due to thrombosis of cerebral arteries

1382.3

323.0

390

PA2BC

NOMESCO Finland

Cerebral extensive angiography with X-ray

561.0

323.0

1042

I69.1

ICD-10 Finland

Sequelae of intracerebral haemorrhage

971.2

323.0

367

PA2BD

NOMESCO Finland

Extensive CT angiography of brain

64.6

323.0

964

175

AAF00

NOMESCO Finland

Ventriculostomy

135.8

323.0

431

I69.3

ICD-10 Finland

Sequelae of cerebral infarction

106.2

323.0

808

I60.7

ICD-10 Finland

Subarachnoid haemorrhage from intracranial artery, unspecified

+∞

323.0

416

AA1AD

NOMESCO Finland

CT of head and brain

5.7

323.0

2853

7875

I67.1

ICD-10 Finland

Cerebral aneurysm, nonruptured

10415.0

323.0

2969

4300A

ICD-9 Finland

Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACHNOID. POST ANEURYSMA SACCULARE]

+∞

323.0

434

I60.1

ICD-10 Finland

Subarachnoid haemorrhage from middle cerebral artery

+∞

323.0

673

PA2CC

NOMESCO Finland

Cerebral very extensive angiography with X-ray

477.6

323.0

801

I61.9

ICD-10 Finland

Intracerebral haemorrhage, unspecified

660.3

320.9

315

PA3AC

NOMESCO Finland

Carotis angiography with X-ray

323.8

303.6

306

PA2KT

NOMESCO Finland

Endovascular closure of brain aneurysm

2881.5

297.9

286

K90

ICPC

Stroke/cerebrovascular accident

34.1

292.3

386

120

I61.0

ICD-10 Finland

Intracerebral haemorrhage in hemisphere, subcortical

591.9

288.2

284

PA2AC

NOMESCO Finland

Cerebral angiography with X-ray

304.0

258.0

261

R51.80

ICD-10 Finland

Headache

3.6

254.1

1315

4237

I60.8

ICD-10 Finland

Other subarachnoid haemorrhage

+∞

246.4

235

43090

ICD-8 Finland

Subarachnoid haemorrhage, Postaneurysma sacculare, hypertonia non indicata

+∞

243.2

232

PA2YT

NOMESCO Finland

Cerebral artery PTA with stent

+∞

243.2

232

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

3.3

233.8

1419

5135

PA2MT

NOMESCO Finland

Endovascular closure of very extensive brain aneurysm

+∞

220.0

210

PA2BG

NOMESCO Finland

MRI examination of vessels in the head with high intensity magnet

49.8

220.0

268

111

Kela drug reimbursment

Epilepsy and comparable convulsive disorders

6.1

216.4

637

1146

I60.3

ICD-10 Finland

Subarachnoid haemorrhage from posterior communicating artery

+∞

212.6

203

XA800

NOMESCO Finland

Neuropsychological investigation

8.4

206.9

479

609

I60.6

ICD-10 Finland

Subarachnoid haemorrhage from other intracranial arteries

+∞

201.1

192

N03AB02

ATC

phenytoin; systemic

19.5

197.9

307

165

B01AC04

ATC

clopidogrel; oral

3.0

191.5

1278

4862

PA6BD

NOMESCO Finland

Extensive CT of neck arteries

7.7

189.7

466

649

AA1BG

NOMESCO Finland

Standard MRI examination of brain with high intensity magnet

4.3

189.3

780

2017

AA1CG

NOMESCO Finland

Extensive MRI examination of brain with high intensity magnet

4.2

183.6

759

1966

WX700

NOMESCO Finland

Respiratory and circulatory monitoring

2.8

182.9

1392

5748

I63.4

ICD-10 Finland

Cerebral infarction due to embolism of cerebral arteries

913.7

182.2

178

AAF05

NOMESCO Finland

Ventriculoperitoneal shunt

15.7

174.3

293

195

43099

ICD-8 Finland

Subarachnoid haemorrhage, Without mention of hypertension

+∞

173.7

166

4309X

ICD-9 Finland

Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACHNOIDALIS NUD]

+∞

171.6

164

G91.0

ICD-10 Finland

Communicating hydrocephalus

37.4

168.2

217

S06.5

ICD-10 Finland

Traumatic subdural haemorrhage

7.2

161.9

412

602

B01AC30

ATC

platelet aggregation inhibitors excl. heparin - combinations

5.8

160.2

485

894

4373A

ICD-9 Finland

Other and ill-defined cerebrovascular disease, Cerebral aneurysm, nonruptured

+∞

160.0

153

PA2AD

NOMESCO Finland

CT angiography of brain

63.4

158.3

185

I60.4

ICD-10 Finland

Subarachnoid haemorrhage from basilar artery

+∞

156.9

150

XXA00

NOMESCO Finland

Clinical examination requiring general anaesthesia

34.1

153.4

202

ZXD05

NOMESCO Finland

Urgent procedure

2.2

151.8

2208

12568

K91

ICPC

Cerebrovascular disease

29.8

150.5

205

AA5PD

NOMESCO Finland

CT examination of brain pefusion

58.6

149.6

177

AA9CW

NOMESCO Finland

110.8

148.8

162

N03AX14

ATC

levetiracetam; systemic

8.4

145.3

334

416

PA4AC

NOMESCO Finland

Vertebralis angiography with X-ray

142.4

143.9

153

GD1QA

NOMESCO Finland

Supine thorax X-ray examination

2.6

138.0

1193

5212

I61.1

ICD-10 Finland

Intracerebral haemorrhage in hemisphere, cortical

+∞

136.9

131

AA5BD

NOMESCO Finland

CT of cerebral ischaemia

15.6

135.7

228

151

G40.29

ICD-10 Finland

Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures

10.5

129.6

262

260

N18

ICPC

Paralysis/weakness

13.3

125.7

226

176

I63.0

ICD-10 Finland

Cerebral infarction due to thrombosis of precerebral arteries

1221.3

123.3

120

G45.9

ICD-10 Finland

Transient cerebral ischaemic attack, unspecified

3.6

122.6

604

1797

I65.2

ICD-10 Finland

Occlusion and stenosis of carotid artery

90.6

119.5

133

G40.22

ICD-10 Finland

Complex partial epileptic seizure with secondary generalization

9.1

119.4

261

298

G40.9

ICD-10 Finland

Epilepsy, unspecified

5.8

114.9

345

625

H53.4

ICD-10 Finland

Visual field defects

9.9

114.6

238

248

S06.6

ICD-10 Finland

Traumatic subarachnoid haemorrhage

14.1

109.9

192

140

205

Kela drug reimbursment

Chronic hypertension

1.9

106.8

2046

12581

I63.8

ICD-10 Finland

Other cerebral infarction

138.5

102.3

109

R4150

NOMESCO Finland

Neuropsychological rehabilitation

27.4

102.3

142

4380A

ICD-9 Finland

Late effects of cerebrovascular disease[SEQUELAE MORBI CEREBROVASCULARIS]

+∞

101.3

I10

ICD-10 Finland

Essential (primary) hypertension

1.7

97.3

3820

29382

N03AF02

ATC

oxcarbazepine; oral

5.2

93.5

308

621

I63.1

ICD-10 Finland

Cerebral infarction due to embolism of precerebral arteries

+∞

88.7

Z2445

NOMESCO Finland

Psychologist

4.9

88.2

305

648

N03AF01

ATC

carbamazepine; oral, rectal

3.4

87.6

460

1428

I62.0

ICD-10 Finland

Nontraumatic subdural haemorrhage

299.4

86.9

R29.8

ICD-10 Finland

Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems

2.7

85.2

625

2432

ZXD35

NOMESCO Finland

Usual procedure

4.2

85.1

345

860

182

Kela drug reimbursment

Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide

6.9

83.3

216

322

PA7BD

NOMESCO Finland

CT angiography of neck and brain

8.4

81.6

186

228

I67.9

ICD-10 Finland

Cerebrovascular disease, unspecified

57.3

81.1

PA7AD

NOMESCO Finland

CT angiography of head and neck vasculature

6.2

80.2

226

377

PA7CD

NOMESCO Finland

CT angiography of neck and brain, extensive

13.5

78.9

140

106

Q28.2

ICD-10 Finland

Arteriovenous malformation of cerebral vessels

43.2

78.7

AA1DG

NOMESCO Finland

Very extensive MRI examination of brain with high intensity magnet

4.9

77.7

269

572

R56.8

ICD-10 Finland

Other and unspecified convulsions

3.6

77.5

373

1079

PAF14

NOMESCO Finland

Thrombendarterectomy of internal carotid artery

87.2

77.1

R42

ICD-10 Finland

Dizziness and giddiness

1.9

75.3

1401

8330

C08CA06

ATC

nimodipine; systemic

83.1

73.1

PA2AG

NOMESCO Finland

Restrected MRI examination of vessels in the head with high intensity magnet

45.6

73.1

ZXE10

NOMESCO Finland

More than one and less than three hours

1.7

73.1

2315

16215

I63.5

ICD-10 Finland

Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries

+∞

73.0

I60.5

ICD-10 Finland

Subarachnoid haemorrhage from vertebral artery

+∞

72.0

G44.2

ICD-10 Finland

Tension-type headache

2.2

71.8

849

4213

N03AG01

ATC

valproic acid; systemic, rectal

3.1

70.5

422

1435

XCK00

NOMESCO Finland

Perimetry

2.6

68.2

531

2128

G40.20

ICD-10 Finland

Complex partial seizures with only alteration of consciousness

10.7

68.2

135

129

G45.1

ICD-10 Finland

Carotid artery syndrome (hemispheric)

4.4

67.0

256

602

WX882

NOMESCO Finland

High dependency care

4.2

65.6

261

638

ZXE20

NOMESCO Finland

More than three and less than five hours

2.0

65.0

947

5113

PA2CG

NOMESCO Finland

Extensive MRI examination of vessels in the head with high intensity magnet

30.4

64.7

C08CA01

ATC

amlodipine; oral

1.6

62.7

2257

16179

AAD10

NOMESCO Finland

Evacuation of chronic subdural haematoma

9.0

61.2

133

151

I69.8

ICD-10 Finland

Sequelae of other and unspecified cerebrovascular diseases

85.9

61.0

R4120

NOMESCO Finland

Occupational therapy

2.9

60.9

388

1373

AA1BM

NOMESCO Finland

MRI examination of brain with 3 Tesla magnet

7.5

59.7

145

197

I60

ICD-10 Finland

Subarachnoid haemorrhage

573.1

57.7

4340A

ICD-9 Finland

Occlusion of cerebral arteries, Cerebral thrombosis

+∞

55.3

W01

ICD-10 Finland

Fall on same level from slipping, tripping and stumbling

1.6

55.2

1808

12546

I63.2

ICD-10 Finland

Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries

542.5

54.6

Z03.3

ICD-10 Finland

Observation for suspected nervous system disorder

2.6

53.8

431

1752

I69.2

ICD-10 Finland

Sequelae of other nontraumatic intracranial haemorrhage

267.9

52.2

WX000

NOMESCO Finland

Monitoring vital functions without anesthesy

3.2

52.2

294

957

TAB00

NOMESCO Finland

Lumbar puncture

3.1

52.1

307

1031

ZXM40

NOMESCO Finland

Use of fluorescent substance

55.9

51.6

Z50.8

ICD-10 Finland

Care involving use of other rehabilitation procedures

2.4

51.1

465

2021

XX4AW

NOMESCO Finland

34.0

49.1

PA6DE

NOMESCO Finland

Neck artery ultrasound examination with Doppler method

3.2

48.5

275

896

R47.0

ICD-10 Finland

Dysphasia and aphasia

14.2

48.3

I61.8

ICD-10 Finland

Other intracerebral haemorrhage

+∞

48.0

G40.2

ICD-10 Finland

Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures

9.5

47.7

100

107

N02BE01

ATC

paracetamol; systemic, rectal

1.6

47.6

5254

47345

AAB30

NOMESCO Finland

Evacuation of spontaneous intracranial haematoma

241.7

47.0

43000

ICD-8 Finland

Subarachnoid haemorrhage, Post aneyrisma sacculare, cum hypertonia

+∞

46.9

I61.5

ICD-10 Finland

Intracerebral haemorrhage, intraventricular

+∞

45.9

H53.2

ICD-10 Finland

Diplopia

3.4

45.1

226

674

C10AA05

ATC

atorvastatin; oral

1.5

44.1

2224

16867

I67.0

ICD-10 Finland

Dissection of cerebral arteries, nonruptured

+∞

43.8

R51

ICD-10 Finland

Headache

2.7

42.7

307

1170

N19

ICPC

Speech disorder

9.1

42.6

101

Q61.2

ICD-10 Finland

Polycystic kidney, autosomal dominant

9.3

42.6

AAF20

NOMESCO Finland

Revision of shunt of ventricle of brain

14.2

42.6

B01AC07

ATC

dipyridamole; systemic

2.9

42.4

268

943

AA1AM

NOMESCO Finland

Short MRI examination of brain with 3 Tesla magnet

26.6

41.9

XFP96

NOMESCO Finland

Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation

3.7

41.8

193

539

G91.9

ICD-10 Finland

Hydrocephalus, unspecified

12.4

41.7

C07AB07

ATC

bisoprolol; oral

1.4

41.3

2841

22846

G45.0

ICD-10 Finland

Vertebro-basilar artery syndrome

3.8

41.1

180

481

XF400

NOMESCO Finland

ECG with 12 standard connections

1.7

41.1

953

5944

I64

ICD-10 Finland

Stroke, not specified as haemorrhage or infarction

39.6

40.6

WX872

NOMESCO Finland

Intensive care

2.5

40.4

329

1347

R41.8

ICD-10 Finland

Other and unspecified symptoms and signs involving cognitive functions and awareness

2.0

40.0

524

2683

GD1PA

NOMESCO Finland

X-ray examination of the lungs in one projection

2.1

39.6

506

2560

AAL10

NOMESCO Finland

Intracranial endovascular thrombolysis

+∞

39.6

H49.0

ICD-10 Finland

Third [oculomotor] nerve palsy

11.3

39.5

G81.9

ICD-10 Finland

Hemiplegia, unspecified

8.4

38.9

105

WX408

NOMESCO Finland

General anesthesy, balanced

1.5

38.7

1538

11001

C07AB02

ATC

metoprolol; systemic

1.6

38.7

1292

8868

Q28.3

ICD-10 Finland

Other malformations of cerebral vessels

13.9

38.2

GBB00

NOMESCO Finland

Tracheostomy

5.7

37.6

111

198

C10AA01

ATC

simvastatin; oral

1.4

37.5

2619

20981

GD1AA

NOMESCO Finland

Thorax X-ray examination

1.4

37.0

2524

20115

R1230

NOMESCO Finland

Neuropsychological evaluation of need and possibilities to rehabilitation

10.1

36.8

I62.9

ICD-10 Finland

Intracranial haemorrhage (nontraumatic), unspecified

191.0

36.8

G91.1

ICD-10 Finland

Obstructive hydrocephalus

13.1

36.8

JN3AA

NOMESCO Finland

Abdominal X-ray examination without contrast

2.5

36.3

308

1288

F10.1

ICD-10 Finland

Mental and behavioural disorders due to use of alcohol, Harmful use

2.3

35.9

359

1630

C09AA02

ATC

enalapril; systemic

1.6

35.3

1211

8344

A28

ICPC

Limited function/disability NOS

1.7

35.3

880

5583

Z01.0

ICD-10 Finland

Examination of eyes and vision

1.6

35.2

937

6052

J18.9

ICD-10 Finland

Pneumonia, unspecified

1.5

35.0

1363

9670

WX730

NOMESCO Finland

Conventional respirator

4.5

34.9

128

291

G40.10

ICD-10 Finland

Simple partial seizures

7.8

34.7

105

Z3231

NOMESCO Finland

Registered nurse

1.5

33.8

1535

11248

G46.3*I67.9

ICD-10 Finland

Brain stem stroke syndrome (I60-I67+)

175.9

33.7

AA1CM

NOMESCO Finland

Extensive MRI examination of brain with 3 Tesla magnet

3.8

33.5

146

390

G40.12

ICD-10 Finland

Simple partial seizures with secondary generalization

8.9

33.4

43098

ICD-8 Finland

Subarachnoid haemorrhage, Alia definita, hypertonia non indicata

+∞

33.4

G43.1

ICD-10 Finland

Migraine with aura [classical migraine]

2.4

33.2

307

1342

N06AB04

ATC

citalopram; systemic

1.5

33.1

1202

8377

R1260

NOMESCO Finland

Evaluation of communicative skills

4.8

32.9

111

232

S06.3

ICD-10 Finland

Focal brain injury

5.0

32.5

107

218

H53.1

ICD-10 Finland

Subjective visual disturbances

2.2

32.3

364

1745

G46.4*I67.9

ICD-10 Finland

Cerebellar stroke syndrome

+∞

32.3

I61.4

ICD-10 Finland

Intracerebral haemorrhage in cerebellum

+∞

32.3

W19

ICD-10 Finland

Unspecified fall

1.9

32.2

522

2891

SPAT1224

SPAT

Implementation of speech therapy rehabilitation plan

5.3

32.0

100

192

R4130

NOMESCO Finland

Speech therapy

4.1

31.0

123

302

WX892

NOMESCO Finland

Monitored bed care

2.0

31.0

414

2130

SPAT1217

SPAT

Assessment of need for services (elderly/care support)

1.9

30.8

445

2361

PA7RT

NOMESCO Finland

Medical infusion to cerebral artery

110.5

30.7

I67.2

ICD-10 Finland

Cerebral atherosclerosis

46.5

30.6

J69.0

ICD-10 Finland

Pneumonitis due to food and vomit

3.8

30.5

133

356

PA2VT

NOMESCO Finland

Intravascular evacuation of brain artery embolus

+∞

30.2

I67.6

ICD-10 Finland

Nonpyogenic thrombosis of intracranial venous system

+∞

30.2

I61

ICD-10 Finland

Intracerebral haemorrhage

+∞

30.2

AAD05

NOMESCO Finland

Evacuation of acute subdural haematoma

13.8

30.2

I69

ICD-10 Finland

Sequelae of cerebrovascular disease

38.2

30.2

AAK00

NOMESCO Finland

Cranioplasty

38.2

30.2

T90.5

ICD-10 Finland

Sequelae of intracranial injury

5.5

30.2

164

AAC40

NOMESCO Finland

Extirpation of intracranial arterio-venous malformation

58.6

30.1

B01AA03

ATC

warfarin; systemic

1.5

29.8

1121

7853

R55

ICD-10 Finland

Syncope and collapse

1.7

29.8

603

3589

PAN14

NOMESCO Finland

Plastic repair of arteries internal carotid artery

83.0

29.7

AAK80

NOMESCO Finland

Partial excision of skull cap

155.7

29.7

M03BX01

ATC

baclofen; systemic

4.0

29.4

122

313

TPH15

NOMESCO Finland

Insertion of central venous catheter through external or internal jugular vein

2.1

29.4

347

1697

ICD-10 Finland

2.9

29.3

185

649

NK6AI

NOMESCO Finland

Other cone beam scan

50.2

29.3

Z2446

NOMESCO Finland

Social worker

2.1

29.0

342

1672

Z3226

NOMESCO Finland

Physiotherapist

1.5

29.0

1003

6890

AAF15

NOMESCO Finland

Ventriculoatrial shunt

15.3

28.5

AA7AA

NOMESCO Finland

Liquor cerebri shunt X-ray examinatin without contrast

15.3

28.5

S06.0

ICD-10 Finland

Concussion

1.8

28.3

534

3109

PA6AD

NOMESCO Finland

CT of neck arteries

5.9

28.2

137

AAF25

NOMESCO Finland

Removal of shunt of ventricle of brain

18.8

28.2

4301A

ICD-9 Finland

Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACH.POST MALFORMAT.ARTERIOVENOSAM]

+∞

28.1

I72.0

ICD-10 Finland

Aneurysm and dissection of carotid artery

18.0

27.8

C09AA05

ATC

ramipril; oral

1.4

27.8

1382

10248

ZXY02

NOMESCO Finland

Neuropsychologist

10.1

27.6

SPAT1229

SPAT

Assessment of need for aid

1.8

27.6

472

2659

Z00.4

ICD-10 Finland

General psychiatric examination, not elsewhere classified

1.9

27.4

394

2086

N28

ICPC

Limited function/disability (N)

4.1

27.3

109

270

SPAT1292

SPAT

Other function in accordance with SHToL (Finnish classification of nursing interventions)

1.8

27.3

522

3047

WW200

SPAT

1.7

27.3

568

3404

N05AH04

ATC

quetiapine; oral

1.6

27.3

800

5276

XPX99

NOMESCO Finland

Other diagnostic examination of periferal vessel

2.0

27.2

366

1890

43009

ICD-8 Finland

Subarachnoid haemorrhage, NUD, cum hypertonia

+∞

27.1

R20.2

ICD-10 Finland

Paraesthesia of skin

2.1

26.8

333

1663

I61.6

ICD-10 Finland

Intracerebral haemorrhage, multiple localized

272.1

26.7

F32.9

ICD-10 Finland

Depressive episode, unspecified

1.7

26.7

559

3360

N06AB10

ATC

escitalopram; oral

1.5

26.5

951

6576

G40

ICD-10 Finland

Epilepsy

6.5

26.3

107

SPAT1216

SPAT

Assessment of functional ability

1.5

26.0

870

5918

N06AX11

ATC

mirtazapine; oral

1.4

25.9

1703

13261

R53

ICD-10 Finland

Malaise and fatigue

1.5

25.9

1062

7558

G43.0

ICD-10 Finland

Migraine without aura [common migraine]

2.4

25.7

228

976

G43.9

ICD-10 Finland

Migraine, unspecified

2.3

25.4

246

1101

TPH04

NOMESCO Finland

Cathetrisation of vein

1.5

25.2

1092

7854

R41.0

ICD-10 Finland

Disorientation, unspecified

2.7

25.2

179

680

315

Kela drug reimbursment

Clopidogrel

5.8

24.5

122

G40.19

ICD-10 Finland

Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures

7.2

24.2

SPAT1226

SPAT

Implementation of occupational therapy rehabilitation plan

2.8

24.0

159

579

I61.3

ICD-10 Finland

Intracerebral haemorrhage in brain stem

+∞

24.0

SPAT1230

SPAT

Aid fitting and borrowing and monitoring of use

1.5

23.7

933

6567

AA1AA

NOMESCO Finland

Head X-ray examination

5.0

23.4

154

N05BA04

ATC

oxazepam; oral

1.4

23.3

1321

9995

N05BA01

ATC

diazepam; systemic, rectal

1.6

23.1

734

4922

I65.0

ICD-10 Finland

Occlusion and stenosis of vertebral artery

+∞

22.9

43091

ICD-8 Finland

Subarachnoid haemorrhage, Postaneyrisma arteriovenosum, hypertonia non indicata

+∞

22.9

TPX22

NOMESCO Finland

Intravenous arterial thrombolysis

14.7

22.9

PA2BM

NOMESCO Finland

MRI examination of vessels in the head with 3 Tesla magnet

25.9

22.6

N02AE01

ATC

buprenorphine; parenteral, sublingual, transdermal

1.6

22.6

696

4634

N05BA09

ATC

clobazam; oral

9.8

22.5

E87.1

ICD-10 Finland

Hypo-osmolality and hyponatraemia

2.1

22.4

253

1216

N02AX02

ATC

tramadol; systemic, rectal

1.3

22.3

2367

19755

C09CA06

ATC

candesartan; oral

1.4

22.2

1158

8615

P20

ICPC

Memory disturbance

1.6

22.2

668

4421

SPAT1252

SPAT

Overall medication plan or its review

1.8

22.1

401

2300

N06AA09

ATC

amitriptyline; systemic

1.6

22.1

564

3578

TPH07

NOMESCO Finland

Cathetrisation of artery

1.6

22.0

545

3430

PA6AG

NOMESCO Finland

Limited MRI examination of neck vasculature with high intensity magnet

9.8

22.0

I61.2

ICD-10 Finland

Intracerebral haemorrhage in hemisphere, unspecified

+∞

21.9

PA7KT

NOMESCO Finland

Temporary closure of brain artery

+∞

21.9

I67.8

ICD-10 Finland

Other specified cerebrovascular diseases

29.1

21.8

XCW99

NOMESCO Finland

Other investigative procedure of eye

1.6

21.7

604

3918

G94.2

ICD-10 Finland

Hydrocephalus in other diseases classified elsewhere

80.4

21.7

Q61.3

ICD-10 Finland

Polycystic kidney, unspecified

7.3

21.6

XX1ZW

NOMESCO Finland

Very extensive written report from radiologist

8.3

21.3

AAD15

NOMESCO Finland

Evacuation of traumatic intracerebral haematoma

50.1

21.1

A06AD11

ATC

lactulose; oral

1.5

21.1

800

5580

183

Kela drug reimbursment

Lamotrigin and topiramate

5.4

21.0

117

N07BA03

ATC

varenicline; oral

2.1

21.0

254

1256

SPAT1222

SPAT

Counselling/guidance promoting independent living

1.5

20.9

815

5714

SPAT1137

SPAT

Taking care of patient’s/customer’s hygiene

1.9

20.7

320

1738

2132

FHL

Ventricular operators sunt

77.0

20.7

PA2HT

NOMESCO Finland

Extensive embolisation of arterio-venous malformation of the brain

77.0

20.7

AA1DM

NOMESCO Finland

Very extensive MRI examination of brain with 3 Tesla magnet

5.2

20.6

124

I70.2

ICD-10 Finland

Atherosclerosis of arteries of extremities

1.7

20.5

460

2815

N03AX09

ATC

lamotrigine; oral

2.2

20.5

209

959

N01

ICPC

Headache

1.7

20.4

412

2444

G45.3

ICD-10 Finland

Amaurosis fugax

3.1

20.2

110

354

C03CA01

ATC

furosemide; systemic

1.3

20.2

1621

12944

AA1CD

NOMESCO Finland

Very extensive CT of head and brain

3.0

20.1

116

387

Z50.9

ICD-10 Finland

Care involving use of rehabilitation procedure, unspecified

2.2

20.1

215

1011

PA6BG

NOMESCO Finland

MRI examination of neck vasculature with high intensity magnet

8.6

20.0

G91.8

ICD-10 Finland

Other hydrocephalus

23.4

19.9

N10

ICD-10 Finland

Acute tubulo-interstitial nephritis

1.5

19.7

665

4517

C09CA01

ATC

losartan; oral

1.4

19.6

1321

10249

H49.2

ICD-10 Finland

Sixth [abducent] nerve palsy

4.6

19.6

149

T36

ICD-10 Finland

Poisoning by systemic antibiotics

2.2

19.6

204

948

NA1AD

NOMESCO Finland

Cervical spine CT examination

2.2

19.4

205

958

N05CF01

ATC

zopiclone; oral

1.3

19.4

1807

14731

C09BA02

ATC

enalapril and diuretics; systemic

1.6

19.3

476

2990

N03AE01

ATC

clonazepam; systemic

1.9

19.2

308

1696

R4110

NOMESCO Finland

Physiotherapy

1.4

19.1

1368

10710

3313A

ICD-9 Finland

Other cerebral degenerations, Communicating hydrocephalus

26.1

19.1

AAA27

NOMESCO Finland

Insertion of intracerebral pressure monitoring device

26.1

19.1

ZXA00

NOMESCO Finland

Right side

1.3

18.9

1507

11998

G81.1

ICD-10 Finland

Spastic hemiplegia

55.1

18.9

TKC20

NOMESCO Finland

Catheterisation of bladder

1.7

18.8

365

2139

Z00.0

ICD-10 Finland

General medical examination

1.4

18.8

944

6953

I62.1

ICD-10 Finland

Nontraumatic extradural haemorrhage

+∞

18.8

G942, I602

ICD-10 Finland

+∞

18.8

C02AC05

ATC

moxonidine; oral

2.0

18.7

254

1315

R90.8

ICD-10 Finland

Other abnormal findings on diagnostic imaging of central nervous system

4.5

18.6

148

AA1BD

NOMESCO Finland

Extensive CT of head and brain

2.4

18.6

153

635

I69.4

ICD-10 Finland

Sequelae of stroke, not specified as haemorrhage or infarction

190.5

18.5

SPAT1254

SPAT

Administration of medicine

1.5

18.5

743

5239

I67.3

ICD-10 Finland

Progressive vascular leukoencephalopathy

8.7

18.3

SPAT1253

SPAT

Initiation, adjustment, discontinuation or repetition of medication

1.3

18.3

1595

12863

N06AX16

ATC

venlafaxine; oral

1.5

18.2

621

4224

C08CA13

ATC

lercanidipine; oral

1.5

17.8

724

5114

AA1AG

NOMESCO Finland

Short MRI examination of brain with median intensity magnet

3.8

17.7

199

4308X

ICD-9 Finland

Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACHNOIDALIS ALIA DEFINITA]

+∞

17.7

43399

ICD-8 Finland

Cerebral thrombosis, Without mention of hypertension

+∞

17.7

N30.0

ICD-10 Finland

Acute cystitis

1.5

17.6

687

4811

WYA30

NOMESCO Finland

Preparations for expected poor cooperation

1.7

17.6

369

2215

Y83

ICD-10 Finland

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

1.7

17.3

398

2449

FP1B5

NOMESCO Finland

Resting ECG, 12 leads

3.0

17.3

328

PA7CC

NOMESCO Finland

Very extensive angiography of arteries of neck and brain

20.9

17.3

S01.0

ICD-10 Finland

Open wound of scalp

1.7

17.2

374

2267

X59

ICD-10 Finland

Exposure to unspecified factor

1.4

17.2

903

6694

Z82.3

ICD-10 Finland

Family history of stroke

10.4

17.1

G00.9

ICD-10 Finland

Bacterial meningitis, unspecified

12.5

17.1

E78.01

ICD-10 Finland

Pure hypercholesterolaemia

1.4

17.0

1013

7680

G44.8

ICD-10 Finland

Other specified headache syndromes

3.7

16.9

197

C08CA02

ATC

felodipine; oral

1.5

16.9

527

3509

F32.2

ICD-10 Finland

Severe depressive episode without psychotic symptoms

1.8

16.7

282

1581

R50.9

ICD-10 Finland

Fever, unspecified

1.5

16.6

656

4603

L28

ICPC

Limited function/disability (L)

1.4

16.6

813

5954

N88

ICPC

Epilepsy

5.9

16.6

I63

ICD-10 Finland

Cerebral infarction

13.4

16.4

3454A

ICD-9 Finland

Epilepsy, Partial epilepsy, with impairment of consciousness[EPILEPSIA GENERALISATA SECUNDARIA]

11.2

16.2

FM1BE

NOMESCO Finland

Cardiac ultrasound examination through oesophagus

1.8

15.8

286

1643

C08CA05

ATC

nifedipine; systemic

1.7

15.8

346

2104

SPAT1301

SPAT

No procedures

1.3

15.7

1670

13781

W10

ICD-10 Finland

Fall on and from stairs and steps

1.8

15.7

251

1381

X69

ICD-10 Finland

Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances

2.3

15.7

150

671

WX704

NOMESCO Finland

Intubation

1.7

15.6

360

2220

2164

FHL

Crotigree

+∞

15.6

N03AX16

ATC

pregabalin; oral

1.3

15.4

1223

9690

SPAT1234

SPAT

Support of social functional capacity

1.8

15.4

266

1506

N03AX12

ATC

gabapentin; oral

1.4

15.4

780

5744

7840A

ICD-9 Finland

Symptoms involving head and neck, Headache

3.6

15.3

194

R1250

NOMESCO Finland

Evaluation of functional capability

2.5

15.2

121

493

N02AA05

ATC

oxycodone; systemic

1.4

15.2

756

5545

UJD10

NOMESCO Finland

Esophagoscopy, gastroscopy and duodenoscopy

1.3

15.1

1512

12368

S02.11

ICD-10 Finland

Fracture of base of skull, open

7.5

15.1

J15.9

ICD-10 Finland

Bacterial pneumonia, unspecified

1.6

15.0

434

2835

N02AA59

ATC

codeine, combinations excl. psycholeptics; systemic

1.2

15.0

2440

21179

PA2JT

NOMESCO Finland

Very extensive embolisation of arterio-venous malformation of the brain

31.7

14.8

R11

ICD-10 Finland

Nausea and vomiting

1.6

14.8

380

2413

RP120

NOMESCO Finland

56.8

14.8

XX3XW

NOMESCO Finland

5.3

14.7

G41.9

ICD-10 Finland

Status epilepticus, unspecified

5.6

14.7

SPAT1223

SPAT

Implementation of physical therapy rehabilitation plan

1.3

14.6

1507

12369

I65.3

ICD-10 Finland

Occlusion and stenosis of multiple and bilateral precerebral arteries

+∞

14.6

AAC10

NOMESCO Finland

Reinforcement of intracranial aneurysm wall

+∞

14.6

AAC20

NOMESCO Finland

Anastomosis to intracranial vessel

+∞

14.6

YKA02

NOMESCO Finland

Excision of kidneys from cadaver donor

80.3

14.6

G40.89

ICD-10 Finland

Other epilepsy

6.4

14.4

T81.4

ICD-10 Finland

Infection following a procedure, not elsewhere classified

1.5

14.3

523

3607

N03AX18

ATC

lacosamide; systemic

5.1

14.3

G40.1

ICD-10 Finland

Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures

7.8

14.3

AAA20

NOMESCO Finland

Insertion of intraventricular pressure monitoring device

8.2

14.2

F32.10

ICD-10 Finland

Moderate depressive episode without somatic syndrome

1.7

14.2

319

1953

J01EA01

ATC

trimethoprim; systemic

1.3

14.2

1322

10700

T85.0

ICD-10 Finland

Mechanical complication of ventricular intracranial (communicating) shunt

9.7

14.2

Z94.0

ICD-10 Finland

Kidney transplant status

3.4

14.1

203

A02BC03

ATC

lansoprazole; oral

1.3

14.1

1590

13191

F17.29

ICD-10 Finland

Addiction caused by tobacco UNS

2.7

13.9

346

Z01.8

ICD-10 Finland

Other specified special examinations

1.3

13.9

1079

8503

RS221

NOMESCO Finland

3.0

13.8

271

Z71.8

ICD-10 Finland

Other specified counselling

1.3

13.8

1095

8659

A02BC01

ATC

omeprazole; systemic

1.3

13.7

1485

12243

N39.0

ICD-10 Finland

Urinary tract infection, site not specified

1.4

13.7

681

4994

AAF99

NOMESCO Finland

Other shunt operation on ventricle of brain or intracerebral cyst

12.0

13.6

A41.9

ICD-10 Finland

Sepsis, unspecified

2.0

13.5

182

944

4319X

ICD-9 Finland

Intracerebral haemorrhage[HAEMORRHAGIA INTRACEREBRALIS NUD]

+∞

13.5

ZYC01

SPAT

1.7

13.3

253

1477

J44.8

ICD-10 Finland

Other specified chronic obstructive pulmonary disease

1.5

13.3

516

3605

Z25.8

ICD-10 Finland

Need for immunization against other specified single viral diseases

0.6

13.3

250

3915

KAS10

NOMESCO Finland

Allogenic transplantation of kidney from cadaver donor

3.7

13.2

151

Z72.0

ICD-10 Finland

Tobacco use

2.3

13.1

120

529

C01DA08

ATC

isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal

1.3

12.9

1235

10015

F10.09

ICD-10 Finland

Alcohol intoxication UNS

2.6

12.9

379

SPAT1215

SPAT

Assessment of need for medical rehabilitation

1.8

12.8

208

1154

RS313

NOMESCO Finland

7.7

12.8

74789

ICD-8 Finland

Other congenital anomalies of circulatory system, Other specified anomalies of circulatory system

50.1

12.8

S06.2

ICD-10 Finland

Diffuse brain injury

3.4

12.8

176

WX404

NOMESCO Finland

Intravenous generell anesthesy

1.3

12.7

1027

8131

ZXD10

NOMESCO Finland

Scheduled procedure

1.2

12.5

2048

17689

P15

ICPC

Chronic alcohol abuse

2.3

12.5

118

527

4331A

ICD-9 Finland

Occlusion and stenosis of precerebral arteries, Carotid artery[OCCL/STENOSIS ARTERIAE CAROTIS CUM INFARCTU CEREBRI]

+∞

12.5

43008

ICD-8 Finland

Subarachnoid haemorrhage, Alii definiti, cum hypertonia

+∞

12.5

4311A

ICD-9 Finland

Intracerebral haemorrhage[HAEMORRHAGIA INTRACEREBRALIS HYPERTONIA NON INDICAT]

+∞

12.5

I67.7

ICD-10 Finland

Cerebral arteritis, not elsewhere classified

+∞

12.5

R13

ICD-10 Finland

Dysphagia

1.6

12.5

310

1952

H47.2

ICD-10 Finland

Optic atrophy

5.2

12.3

123

Kela drug reimbursment

Chronic disorders of vitamin D metabolism

2.2

12.3

119

538

J01DA01

ATC

[U] cefalexin; systemic

1.2

12.2

3429

31249

FM1AE

NOMESCO Finland

Standard cardiac ultrasound examination

1.3

12.2

854

6618

N29

ICPC

Neurological sympt/complt other

2.4

12.2

411

PA2GT

NOMESCO Finland

Embolisation of arterio-venous malformation of the brain

37.6

12.2

C03AA03

ATC

hydrochlorothiazide; oral

1.4

12.1

516

3672

SPAT1249

SPAT

Treatment-related counselling outside office

1.2

12.1

2008

17356

EB1SA

NOMESCO Finland

Dental X-ray, bite-wing X-ray on one side of the mouth

0.8

12.1

1626

18959

SPAT1251

SPAT

Organisation of medication

1.9

12.1

186

1014

N05AX08

ATC

risperidone; systemic

1.5

11.9

366

2429

ZXE15

NOMESCO Finland

Procedure duration 120 to 149 minutes

2.6

11.9

334

I72.8

ICD-10 Finland

Aneurysm and dissection of other specified arteries

5.5

11.9

D21

ICPC

Swallowing problem

3.1

11.9

209

H34.1

ICD-10 Finland

Central retinal artery occlusion

4.8

11.8

XA400

NOMESCO Finland

EEG

4.8

11.8

I71.4

ICD-10 Finland

Abdominal aortic aneurysm, without mention of rupture

2.1

11.8

124

583

TAA40

NOMESCO Finland

Cathetrisation of cerebrospinal fluid through skin

7.0

11.8

F10.29

ICD-10 Finland

Addiction caused by alcohol UNS

2.2

11.7

113

511

FB1BD

NOMESCO Finland

Extensive CT examination of arteria pulmonalis

1.5

11.7

372

2489

R47.1

ICD-10 Finland

Dysarthria and anarthria

4.1

11.6

108

R51.81

ICD-10 Finland

Facial pain NOS

2.3

11.6

109

485

J01MA02

ATC

ciprofloxacin; systemic

1.2

11.6

2051

17830

XX1XW

NOMESCO Finland

Extensive written report from radiologist

2.3

11.5

103

448

C03EA01

ATC

hydrochlorothiazide and potassium-sparing agents; oral

1.3

11.5

866

6782

C02EA02

ATC

1.7

11.5

229

1358

SPAT1250

SPAT

Comprehensive monitoring of chronic illness

1.3

11.5

1446

12105

S22.3

ICD-10 Finland

Fracture of rib

1.6

11.5

309

1987

SPAT1100

SPAT

Long-term monitoring of blood pressure

1.5

11.5

352

2337

SPAT1240

SPAT

Therapeutic discussion

1.5

11.5

393

2674

I67.5

ICD-10 Finland

Moyamoya disease

+∞

11.5

PH2AE

NOMESCO Finland

Ultrasound examination of lower leg veins

1.4

11.5

529

3823

I70.9

ICD-10 Finland

Generalized and unspecified atherosclerosis

2.7

11.4

296

E78.5

ICD-10 Finland

Hyperlipidaemia, unspecified

1.5

11.4

462

3256

4019X

ICD-9 Finland

Essential hypertension, Unspecified

1.9

11.3

152

791

AN1

Coronary angiography

1.4

11.3

598

4429

JN3AE

NOMESCO Finland

Abdominal ultrasound examination

1.4

11.3

616

4584

N06CA01

ATC

amitriptyline and psycholeptics; systemic

1.4

11.3

516

3723

F05.9

ICD-10 Finland

Delirium, unspecified

2.4

11.3

379

D68.3

ICD-10 Finland

Haemorrhagic disorder due to circulating anticoagulants

6.5

11.2

C10AX09

ATC

ezetimibe; oral

1.4

11.2

506

3642

F10.39

ICD-10 Finland

Withdrawal symptoms caused by alcohol UNS

3.0

11.1

202

XX3DW

NOMESCO Finland

Time consuming IT work

1.4

11.1

501

3603

CS424

NOMESCO Finland

Visual field testing with Goldmann perimetry

3.6

11.1

138

SPAT1101

SPAT

Orthostatic test

1.7

11.1

228

1365

CS444

NOMESCO Finland

Visual field testing with Octopus automated perimetry

1.9

11.1

156

827

G40.00

ICD-10 Finland

Benign childhood epilepsy with centrotemporal EEG spikes

8.0

11.0

ZXE30

NOMESCO Finland

More than five and less than seven hours

1.7

11.0

240

1462

A98

ICPC

Health maint/preventive medicine

0.8

11.0

5312

55149

ZY020

NOMESCO Finland

Telephone, letter or other consultation without direct patient contact

1.6

11.0

316

2066

N07BB01

ATC

disulfiram; oral

1.8

11.0

177

982

Z43.0

ICD-10 Finland

Attention to tracheostomy

13.9

10.9

I25.1

ICD-10 Finland

Atherosclerotic heart disease

1.3

10.9

1107

9027

Z50.5

ICD-10 Finland

Speech therapy

3.0

10.9

200

SPAT1053

SPAT

Memory test

1.3

10.8

774

6017

SPAT1276

SPAT

Outlining of treatment with patient or their family members

2.1

10.8

121

586

N03AX11

ATC

topiramate; oral

2.2

10.7

106

486

R2120

NOMESCO Finland

Counselling and guidance concerning rehabilitation services and social security

3.6

10.7

127

206

Kela drug reimbursment

Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease

1.3

10.7

921

7349

R60.0

ICD-10 Finland

Localized oedema

1.4

10.7

537

3939

JDB10

NOMESCO Finland

Percutaneous gastrostomy

2.8

10.7

231

138

Kela drug reimbursment

Severe anaemia associated with chronic renal failure

2.2

10.6

103

469

3451A

ICD-9 Finland

Epilepsy, Generalised convulsive epilepsy

7.5

10.6

M01AH05

ATC

etoricoxib; oral

0.8

10.6

2591

28679

I95.1

ICD-10 Finland

Orthostatic hypotension

1.9

10.6

158

855

A11CC03

ATC

alfacalcidol; systemic

2.1

10.6

113

539

Z76.9

ICD-10 Finland

Person encountering health services in unspecified circumstances

1.5

10.5

317

2095

AAK85

NOMESCO Finland

Replantation of previously excised part of skull cap

110.2

10.4

PA6YT

NOMESCO Finland

Dilatation of carotid artery with stent

110.2

10.4

4331X

ICD-9 Finland

Occlusion and stenosis of precerebral arteries, Carotid artery[OCCL/STENOSIS ARTERIAE CAROTIS SINE INFARCTU CEREBR]

+∞

10.4

4360A

ICD-9 Finland

Acute but ill-defined cerebrovascular disease[MORBUS CEREBROVASCULARIS ACUTUS NON DEFINITUS]

+∞

10.4

G942, I601

ICD-10 Finland

+∞

10.4

A12BA01

ATC

potassium chloride; oral

1.6

10.3

238

1474

S06.4

ICD-10 Finland

Epidural haemorrhage

7.1

10.2

M51.1

ICD-10 Finland

Lumbar and other intervertebral disc disorders with radiculopathy

1.3

10.0

671

5162

H49.1

ICD-10 Finland

Fourth [trochlear] nerve palsy

4.0

10.0

R40.2

ICD-10 Finland

Coma, unspecified

3.2

10.0

162

G40.21

ICD-10 Finland

Partial epileptic seizure with cloudiness and automatism

5.1

10.0

B01AC22

ATC

prasugrel; oral

4.6

10.0

Z04.8

ICD-10 Finland

Examination and observation for other specified reasons

1.4

9.9

537

3996

R06.0

ICD-10 Finland

Dyspnoea

1.2

9.9

1210

10080

SPAT1296

SPAT

Other function in accordance with occupational therapy nomenclature

2.6

9.8

255

R10.4

ICD-10 Finland

Other and unspecified abdominal pain

1.2

9.8

1688

14575

W06

ICD-10 Finland

Fall involving bed

3.4

9.8

137

AA9PW

NOMESCO Finland

26.0

9.8

N05CD07

ATC

temazepam; oral

1.3

9.8

643

4928

I48

ICD-10 Finland

Atrial fibrillation and flutter

1.3

9.8

1114

9202

127

Kela drug reimbursment

Transplant complication

2.5

9.7

300

N06AX21

ATC

duloxetine; oral

1.4

9.7

475

3469

GBB03

NOMESCO Finland

Percutaneous tracheostomy

13.4

9.6

A04

ICPC

Weakness/tiredness general

1.4

9.6

578

4371

G93.90

ICD-10 Finland

Brain death

55.1

9.6

2102

FHL

Exploratory craniotomy and / or cranectomy

55.1

9.6

C07AG02

ATC

carvedilol; oral

1.5

9.6

293

1945

EBA15

NOMESCO Finland

Extraction of large number of teeth

1.8

9.6

174

1004

NA1BG

NOMESCO Finland

Cervical spine MRI examination with high intensity magnet

1.6

9.6

222

1374

AAB00

NOMESCO Finland

Extirpation of intracranial lesion

2.5

9.6

303

EBA00

NOMESCO Finland

Extraction of tooth

1.2

9.6

1519

13007

A49.9

ICD-10 Finland

Bacterial infection, unspecified

1.4

9.5

507

3759

SPAT1231

SPAT

Assessment of adjustments needed in living environment

2.1

9.5

102

487

SPAT1220

SPAT

Assessment of need for rehabilitation and/or rehabilitation plan

1.5

9.4

298

1995

YFA50

NOMESCO Finland

Excision of heart for preparation of homograft

+∞

9.4

4310A

ICD-9 Finland

Intracerebral haemorrhage[HAEMORRHAGIA INTRACEREBRALIS CUM HYPERTONIA]

+∞

9.4

PA6AE

NOMESCO Finland

Ulrasound examination of neck vasculature

3.3

9.4

137

S06.9

ICD-10 Finland

Intracranial injury, unspecified

4.0

9.3

A01

ICPC

Pain general/multiple sites

1.5

9.3

346

2401

KA2AE

NOMESCO Finland

Ultrasound examination transplanted kidney

3.6

9.3

112

N80

ICPC

Head injury other

2.5

9.2

283

H02AB06

ATC

prednisolone; systemic

1.2

9.2

2446

21962

S02.00

ICD-10 Finland

Fracture of the upper part of the head closed

5.2

9.2

G40.09

ICD-10 Finland

Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset

5.4

9.2

L04AA06

ATC

mycophenolic acid; systemic

2.3

9.1

344

EBA30

NOMESCO Finland

Excision of root of tooth

1.6

9.1

242

1556

TJD20

NOMESCO Finland

Change of gastrostomy tube

5.3

9.0

F43.22

ICD-10 Finland

Adaptation disorder with mixed anxiety and depression

1.8

9.0

145

809

G44.1

ICD-10 Finland

Vascular headache, not elsewhere classified

3.5

9.0

115

F43.29

ICD-10 Finland

Adaptation disorder UNS

2.3

8.9

351

M79.6

ICD-10 Finland

Pain in limb

1.2

8.9

1743

15212

I25.9

ICD-10 Finland

Chronic ischaemic heart disease, unspecified

1.4

8.9

470

3480

75310

ICD-8 Finland

Congenital anomalies of urinary system, Ren polycysticus bilateralis

24.0

8.9

G44.0

ICD-10 Finland

Cluster headache syndrome

2.9

8.9

174

F80.1

ICD-10 Finland

Expressive language disorder

4.2

8.8

M54.5

ICD-10 Finland

Low back pain

1.2

8.8

1572

13602

F33.10

ICD-10 Finland

Recurrent depression, moderate episode without somatic syndrome

1.7

8.8

187

1136

H35.6

ICD-10 Finland

Retinal haemorrhage

3.3

8.8

123

R52.2

ICD-10 Finland

Other chronic pain

1.8

8.7

146

823

SPAT1210

SPAT

Application of cast or individual aid

1.6

8.7

195

1202

2127

FHL

Ventriculostomy

50.0

8.7

J67.1

ICD-10 Finland

Bagassosis

50.0

8.7

N30.9

ICD-10 Finland

Cystitis, unspecified

1.5

8.6

257

1703

C01DA14

ATC

isosorbide mononitrate; oral

1.3

8.6

761

6088

A09

ICD-10 Finland

Other gastroenteritis and colitis of infectious and unspecified origin

1.3

8.6

686

5410

7803A

ICD-9 Finland

General symptoms, Convulsions

3.2

8.6

136

7804A

ICD-9 Finland

General symptoms, Dizziness and giddiness

2.4

8.5

279

ZXD00

NOMESCO Finland

Emergency procedure

1.8

8.5

142

801

G43.8

ICD-10 Finland

Other migraine

2.8

8.5

188

Q28.0

ICD-10 Finland

Arteriovenous malformation of precerebral vessels

27.5

8.5

3314A

ICD-9 Finland

Other cerebral degenerations, Obstructive hydrocephalus

20.0

8.5

R41.3

ICD-10 Finland

Other amnesia

1.9

8.5

121

650

C09DA06

ATC

candesartan and diuretics; oral

1.4

8.4

352

2500

G03.9

ICD-10 Finland

Meningitis, unspecified

5.3

8.4

I66.9

ICD-10 Finland

Occlusion and stenosis of unspecified cerebral artery

90.1

8.4

44209

ICD-8 Finland

Other aneurysm, Ruptura non indicata

90.1

8.4

F06.9

ICD-10 Finland

Unspecified mental disorder due to brain damage and dysfunction and to physical disease

5.6

8.4

R04.0

ICD-10 Finland

Epistaxis

1.4

8.4

333

2340

TPH20

NOMESCO Finland

Insertion of central venous catheter through subclavian or brachiocephalic vein

1.9

8.4

122

659

R03BB04

ATC

tiotropium bromide; inhalant

1.4

8.4

484

3639

D32.00

ICD-10 Finland

Benign tumor of the meninges on the outer surface of the cerebrum

2.3

8.4

306

H34.2

ICD-10 Finland

Other retinal artery occlusions

4.2

8.3

ZSA00

NOMESCO Finland

Procedure related to previous procedure classified in chapter A

4.8

8.3

I65.1

ICD-10 Finland

Occlusion and stenosis of basilar artery

+∞

8.3

PA7YT

NOMESCO Finland

Very extensive carotis artery PTA with stent

+∞

8.3

PCU93

NOMESCO Finland

Injection of therapeutic or sclerosing agent into bypass from suprarenal abdominal aorta and visceral arteries

+∞

8.3

2162

FHL

Wall reinforcement, big brain

+∞

8.3

AAC99

NOMESCO Finland

Other operation for aneurysm or other intracranial vascular lesion

+∞

8.3

H43.1

ICD-10 Finland

Vitreous haemorrhage

1.9

8.3

113

596

ZXH06

SPAT

1.9

8.2

115

612

78551

ICD-8 Finland

Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD

1.8

8.2

142

813

ZX122

NOMESCO Finland

Intra-arterial

4.7

8.2

M03BC01

ATC

orphenadrine (citrate); systemic

1.2

8.2

1036

8645

Z49.1

ICD-10 Finland

Extracorporeal dialysis

2.5

8.2

257

AWB00

NOMESCO Finland

Reoperation for superficial infection in surgery of the nervous system

7.5

8.1

Z3229

NOMESCO Finland

Other healthcare associate professional

1.4

8.1

393

2868

R47.8

ICD-10 Finland

Other and unspecified speech disturbances

3.3

8.1

120

C10AA04

ATC

fluvastatin; oral

1.4

8.1

422

3121

PA7ST

NOMESCO Finland

Extensive medical infusion to cerebral artery

33.4

8.1

C07AB03

ATC

atenolol; systemic

1.5

8.1

295

2043

PA7DG

NOMESCO Finland

Very extended MRI examination of vessesl in brain and neck with high intensity magnet

17.2

8.1

SPAT1284

SPAT

Extensive health certificate

1.8

8.0

123

676

Z02.7

ICD-10 Finland

Issue of medical certificate

1.5

8.0

262

1768

PA6CG

NOMESCO Finland

Extensive MRI examination of neck vasculature with high intensity magnet

5.2

8.0

RS340

NOMESCO Finland

5.8

8.0

SPAT1295

SPAT

Other function in accordance with physical therapy nomenclature

1.5

8.0

242

1609

H93.1

ICD-10 Finland

Tinnitus

1.5

7.9

294

2041

PEF23

NOMESCO Finland

Thrombendarterectomy of femoral artery

2.2

7.9

337

F10.20

ICD-10 Finland

Alcohol dependence currently independent

2.1

7.8

396

TK800

NOMESCO Finland

Hemodialysis

2.0

7.8

481

F10.25

ICD-10 Finland

Alcohol dependence continuous use

2.2

7.8

330

F10.9

ICD-10 Finland

Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder

2.9

7.8

155

XX4BW

NOMESCO Finland

8.4

7.8

WW804

NOMESCO Finland

Transfer from treating institution to higher-Level care, accompanied by doctor

8.4

7.8

I11.9

ICD-10 Finland

Hypertensive heart disease without (congestive) heart failure

1.6

7.8

198

1261

79199

ICD-8 Finland

Headache

2.2

7.8

344

I25.2

ICD-10 Finland

Old myocardial infarction

1.4

7.7

302

2116

WW806

NOMESCO Finland

Transfer from treating institution to lower-Level care, accompanied by doctor

45.0

7.7

XA800

SPAT

45.0

7.7

JA1AE

NOMESCO Finland

Ultrasound examination of groin and abdominal wall

2.1

7.7

406

A12AA04

ATC

calcium carbonate; oral

2.2

7.7

348

OAB43

SPAT

0.7

7.7

299

4085

SPAT1243

SPAT

Psychiatric/psychological examination

2.1

7.6

398

PA1AC

NOMESCO Finland

Aortocervical angiongraphy with X-ray

25.0

7.6

J44.9

ICD-10 Finland

Chronic obstructive pulmonary disease, unspecified

1.6

7.6

202

1303

R99

ICD-10 Finland

Other ill-defined and unspecified causes of mortality

2.1

7.5

393

I50.9

ICD-10 Finland

Heart failure, unspecified

1.3

7.4

631

5018

I65.9

ICD-10 Finland

Occlusion and stenosis of unspecified precerebral artery

80.2

7.4

PA2PT

NOMESCO Finland

Permanent closure of brain artery

80.2

7.4

I95.9

ICD-10 Finland

Hypotension, unspecified

2.4

7.4

260

RS222

NOMESCO Finland

2.4

7.4

260

N17

ICPC

Vertigo/dizziness

1.3

7.3

483

3707

C08DB01

ATC

diltiazem; oral

1.5

7.3

258

1771

SPAT1245

SPAT

Provision of support and information to patient’s family members

1.6

7.3

198

1283

F10.31

ICD-10 Finland

Withdrawal symptoms caused by alcohol with seizures

3.0

7.3

136

4341A

ICD-9 Finland

Occlusion of cerebral arteries, Cerebral embolism

+∞

7.3

G942, I690

ICD-10 Finland

+∞

7.3

AAL20

NOMESCO Finland

Endovascular occlusion of intracranial arterio-venous malformation

+∞

7.3

I67

ICD-10 Finland

Other cerebrovascular diseases

+∞

7.3

4349A

ICD-9 Finland

Occlusion of cerebral arteries, Cerebral artery occlusion, unspecified[OCCL/STENOS ARTER.CEREBRALES NUD CUM INFARCTU CEREB]

+∞

7.3

G942, I600

ICD-10 Finland

+∞

7.3

G942, I609

ICD-10 Finland

+∞

7.3

CEC30

NOMESCO Finland

Resection of extraocular muscle

10.8

7.3

M01AE03

ATC

ketoprofen; systemic, rectal

1.2

7.3

1982

17741

J01DB01

ATC

cefalexin; oral

1.2

7.3

4524

43093

G40.11

ICD-10 Finland

Simple partial epileptic seizure that develops into a complex partial seizure

6.8

7.3

5541

FHL

Subclavia and / or carotid endarterectomy, reconstruction or bypass surgery

15.7

7.2

G30.8

ICD-10 Finland

Other Alzheimer disease

2.0

7.2

448

G40.6

ICD-10 Finland

Grand mal seizures, unspecified (with or without petit mal)

4.2

7.2

K89

ICPC

Transient cerebral ischaemia

2.8

7.2

148

F06.7

ICD-10 Finland

Mild cognitive disorder

1.8

7.2

119

672

H02AB04

ATC

methylprednisolone; systemic

1.3

7.1

697

5640

G81.0

ICD-10 Finland

Flaccid hemiplegia

30.0

7.1

F32.00

ICD-10 Finland

Mild depressive episode without somatic syndrome

1.6

7.1

159

979

C09CA03

ATC

valsartan; oral

1.4

7.1

410

3081

G46.4

ICD-10 Finland

Cerebellar stroke syndrome

20.0

7.1

E78.00

ICD-10 Finland

Familial hypercholesterolaemia

1.6

7.1

177

1125

M05BA04

ATC

alendronic acid; oral

1.3

7.1

424

3205

190

Kela drug reimbursment

Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide

2.9

7.1

142

ZXA05

NOMESCO Finland

Left side

1.2

7.1

1296

11205

XX7FW

NOMESCO Finland

6.5

7.1

E11.8

ICD-10 Finland

Type 2 diabetes mellitus, with unspecified complications

1.3

7.1

417

3145

7531A

ICD-9 Finland

Congenital anomalies of urinary system, Cystic kidney disease

12.0

7.1

F33.9

ICD-10 Finland

Recurrent depressive disorder, unspecified

1.7

7.1

140

837

R07.3

ICD-10 Finland

Other chest pain

1.3

7.1

414

3123

N06AB06

ATC

sertraline; oral

1.3

7.0

423

3202

C08DA01

ATC

verapamil; systemic

1.6

7.0

184

1182

D32.02

ICD-10 Finland

Benign tumor of the meninges at the base of the brain

2.6

7.0

181

G97.0

ICD-10 Finland

Cerebrospinal fluid leak from spinal puncture

2.5

7.0

199

K08.3

ICD-10 Finland

Retained dental root

1.4

6.9

294

2098

J01EE01

ATC

sulfamethoxazole and trimethoprim; systemic

1.4

6.9

266

1864

Z03

ICPC

Housing/neighbourhood problem

3.3

6.9

G91.2

ICD-10 Finland

Normal-pressure hydrocephalus

2.3

6.9

269

C07AB05

ATC

betaxolol; oral

1.7

6.9

128

751

H02.4

ICD-10 Finland

Ptosis of eyelid

1.7

6.9

124

719

RS230

NOMESCO Finland

3.5

6.9

F33.2

ICD-10 Finland

Recurrent depressive disorder, current episode severe without psychotic symptoms

1.6

6.8

166

1048

PEC23

NOMESCO Finland

Suture of common femoral artery

4.4

6.8

PBL09

NOMESCO Finland

Construction of arteriovenous fistula from brachial artery

5.0

6.8

E78.9

ICD-10 Finland

Disorder of lipoprotein metabolism, unspecified

1.6

6.8

157

979

RT152

NOMESCO Finland

40.1

6.8

SPAT1297

SPAT

Other function in accordance with speech therapy nomenclature

5.3

6.7

Z98.2

ICD-10 Finland

Presence of cerebrospinal fluid drainage device

16.7

6.7

Angiography of the heart and coronary arteries

1.4

6.7

294

2109

7865A

ICD-9 Finland

Symptoms involving respiratory system and other chest symptoms, Chest pain

2.0

6.7

419

40199

ICD-8 Finland

Essential benign hypertension

1.9

6.7

533

P29

ICPC

Psychological sympt/compl other

1.6

6.7

180

1166

PBM09

NOMESCO Finland

Closure of arteriovenous fistula of brachial artery

22.5

6.7

RT162

NOMESCO Finland

22.5

6.7

X58

ICD-10 Finland

Exposure to other specified factors

1.3

6.7

570

4537

PG1XE

NOMESCO Finland

Other ultrasound examination of blood vessel not elsewhere classified

3.1

6.7

111

I21.49

ICD-10 Finland

Acute subendocardial infarction unspecified coronary artery status

1.4

6.6

255

1786

SPAT1285

SPAT

Provision of consultation response

1.5

6.6

235

1621

R07.4

ICD-10 Finland

Chest pain, unspecified

1.2

6.6

1321

11506

G43.3

ICD-10 Finland

Complicated migraine

2.3

6.6

232

I77.0

ICD-10 Finland

Arteriovenous fistula, acquired

5.9

6.6

WX320

NOMESCO Finland

Spinalanesthesy

0.8

6.6

810

9610

S82.6

ICD-10 Finland

Fracture of lateral malleolus

1.4

6.6

260

1834

SPAT1221

SPAT

Guidance concerning rehabilitation services and livelihood

2.1

6.6

331

6350C

ICD-9 Finland

Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]

1.6

6.6

174

1125

M54.4

ICD-10 Finland

Lumbago with sciatica

1.2

6.5

730

5999

PA2DG

NOMESCO Finland

Very extensive MRI examination of vessels in the head with high intensity magnet

8.7

6.5

280

Kela drug reimbursment

Clopidogrel

2.1

6.5

320

ZXE13

NOMESCO Finland

Procedure duration 90 to 119 minutes

1.7

6.5

117

680

ZXF05

NOMESCO Finland

Interruption of procedure for other patient related reason

3.5

6.5

WZC05

NOMESCO Finland

Specialty-specific consultation based on referral by dentist or doctor

1.5

6.5

211

1430

F45.4

ICD-10 Finland

Persistent somatoform pain disorder

2.1

6.5

348

J46

ICD-10 Finland

Status asthmaticus

1.7

6.5

120

704

S02.10

ICD-10 Finland

Fracture of base of skull, closed

3.6

6.5

T81.0

ICD-10 Finland

Haemorrhage and haematoma complicating a procedure, not elsewhere classified

1.4

6.4

278

1993

N06AX03

ATC

mianserin; oral

1.5

6.4

212

1437

F10.30

ICD-10 Finland

Withdrawal symptoms caused by alcohol uncomplicated

2.4

6.4

201

G41.0

ICD-10 Finland

Grand mal status epilepticus

5.7

6.4

JN3AD

NOMESCO Finland

Abdominal CT examination

1.4

6.4

336

2490

7478X

ICD-9 Finland

Other congenital anomalies of circulatory system, Other specified anomalies of circulatory system

69.9

6.4

C02DE03

ATC

69.9

6.4

PA2AM

NOMESCO Finland

Simple MRI examination of vessels in the head with 3 Tesla magnet

69.9

6.4

PA2CM

NOMESCO Finland

Extensive MRI examination of vessels in the head with 3 Tesla magnet

69.9

6.4

G50.0

ICD-10 Finland

Trigeminal neuralgia

2.0

6.4

390

FN1AC

NOMESCO Finland

Angiography of heart and/or coronary arteries

1.2

6.4

1049

8973

N18.9

ICD-10 Finland

Chronic kidney disease, unspecified

1.4

6.4

253

1783

OAB42

SPAT

1.5

6.4

186

1231

J20.9

ICD-10 Finland

Acute bronchitis, unspecified

1.2

6.4

791

6580

P70

ICPC

Dementia

1.9

6.3

478

213

Kela drug reimbursment

Fat metabolism disorder associated with chronic coronary artery disease

1.4

6.3

333

2472

A41.5

ICD-10 Finland

Sepsis due to other Gram-negative organisms

1.6

6.3

144

895

PA6CM

NOMESCO Finland

Extensive MRI examination of neck vasculature with 3 Tesla magnet

11.0

6.3

RS314

NOMESCO Finland

5.9

6.3

3643

FHL

Vitrectomy through pars Plana

5.5

6.3

KHV

NOMESCO Finland

2.6

6.3

163

PA2BT

NOMESCO Finland

Cerebral artery extensive PTA

+∞

6.2

PA2AT

NOMESCO Finland

Cerebral artery PTA

+∞

6.2

G942, I615

ICD-10 Finland

+∞

6.2

G942, I606

ICD-10 Finland

+∞

6.2

PA1CC

NOMESCO Finland

Extensive aortocervical angiongraphy with X-ray (including 3 to 4 selective injections)

+∞

6.2

I66.0

ICD-10 Finland

Occlusion and stenosis of middle cerebral artery

+∞

6.2

Y3090

ICD-8 Finland

+∞

6.2

PA2CT

NOMESCO Finland

Cerebral artery very extensive PTA

+∞

6.2

2163

FHL

Proxies. Vascular ligation, big brain

+∞

6.2

A46

ICD-10 Finland

Erysipelas

1.3

6.2

644

5249

PBL10

NOMESCO Finland

Construction of arteriovenous fistula from radial artery

2.3

6.2

219

N99

ICPC

Neurological disease other

2.3

6.2

219

AXX01

SPAT

2.1

6.2

305

F01.9

ICD-10 Finland

Vascular dementia, unspecified

2.4

6.2

201

K87

ICPC

Hypertension complicated

1.8

6.2

101

570

K59.09

ICD-10 Finland

Constipation, unspecified

1.4

6.2

260

1855

RF120

NOMESCO Finland

2.2

6.2

252

S06.8

ICD-10 Finland

Other intracranial injuries

5.7

6.1

S22.4

ICD-10 Finland

Multiple fractures of ribs

1.8

6.1

479

F41.2

ICD-10 Finland

Mixed anxiety and depressive disorder

1.4

6.1

247

1749

C02DE04

ATC

1.7

6.1

124

751

J01FA06

ATC

roxithromycin; oral

1.2

6.1

2040

18494

F10.26

ICD-10 Finland

Alcohol dependence periodic alcoholism

2.1

6.1

323

SPAT1050

SPAT

Extensive neurological examination

1.8

6.1

531

SPAT1310

SPAT

Counselling related to known health issue

1.2

6.1

1541

13684

K08.1

ICD-10 Finland

Loss of teeth due to accident, extraction or local periodontal disease

1.3

6.1

471

3703

S09.9

ICD-10 Finland

Unspecified injury of head

2.3

6.0

224

H53.9

ICD-10 Finland

Visual disturbance, unspecified

1.7

6.0

113

668

K92.1

ICD-10 Finland

Melaena

1.5

6.0

214

1479

NAME	I9_SAHANEUR
CONTROL_EXCLUDE	I9_CEREBVASC
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	I9_ANEUR\|I9_ANEURYSM\|I9_SAH
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Parameter	HR [95% CI]	p-value
I9_SAHANEUR	2.173 [1.97, 2.4]	< 0.001
Birth year	0.994 [0.99, 1.0]	0.15

Parameter	HR [95% CI]	p-value
I9_SAHANEUR	2.285 [2.06, 2.53]	< 0.001
Birth year	0.984 [0.97, 0.99]	< 0.001

N-year risk	Females	Males
1	0.19%	0.36%
5	1.138%	2.232%
10	2.866%	5.538%
15	5.712%	10.532%
20	9.658%	17.186%

Aneurysms, operations, SAH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints