Cardiovascular diseases (excluding rheumatic etc)

FG_CVD

cardiovascular disease: A disease involving the cardiovascular system.

Endpoint definition

FinnGen phenotype data

414262 individuals

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Apply sex-specific rule None

414262

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Check conditions None

414262

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

185353

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FG_CVD

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 185353 88849 96504
Unadjusted prevalence (%) 49.15 42.15 58.04
Mean age at first event (years) 53.34 50.89 55.59

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 4.38 [4.12, 4.67] <1e-100 33194
15 years 0.01 2.94 [2.73, 3.17] <1e-100 14394
5 years 0.00 4.22 [3.88, 4.59] <1e-100 6088
1 year 0.00 19.24 [16.49, 22.46] <1e-100 4316

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: FG_CVD – Cardiovascular diseases (excluding rheumatic etc)
GWS hits: 74

Survival analyses between endpoints

Plot

before Cardiovascular diseases (excluding rheumatic etc)
after Cardiovascular diseases (excluding rheumatic etc)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cardiovascular diseases (excluding rheumatic etc)

Endpoint not on priority list, no data to show.