Cardiovascular diseases (excluding rheumatic etc)


cardiovascular disease: A disease involving the cardiovascular system.

Endpoint definition

FinnGen phenotype data

414262 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Remove individuals based on genotype QC


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Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 185353 88849 96504
Unadjusted prevalence (%) 49.15 42.15 58.04
Mean age at first event (years) 53.34 50.89 55.59


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 4.38 [4.12, 4.67] <1e-100 33194
15 years 0.01 2.94 [2.73, 3.17] <1e-100 14394
5 years 0.00 4.22 [3.88, 4.59] <1e-100 6088
1 year 0.00 19.24 [16.49, 22.46] <1e-100 4316

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: FG_CVD – Cardiovascular diseases (excluding rheumatic etc)
GWS hits: 74

Survival analyses between endpoints


before Cardiovascular diseases (excluding rheumatic etc)
after Cardiovascular diseases (excluding rheumatic etc)

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Drugs most likely to be purchased after Cardiovascular diseases (excluding rheumatic etc)

Endpoint not on priority list, no data to show.