osteoarthritis: A noninflammatory degenerative joint disease occurring chiefly in older persons, characterised by degeneration of the articular cartilage, hypertrophy of bone at the margins and changes in the synovial membrane. It is accompanied by pain and stiffness, particularly after prolonged activity.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2172 |
4. Check minimum number of eventsNone |
2172 |
5. Include endpointsNone |
2172 |
6. Filter based on genotype QC (FinnGen only) |
2172 |
Control definitions (FinnGen only)
- Control exclude
- L12_OTHERSKINSUBCUTIS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L91
- Name in latin
- Cicatrix cheloides
Similar endpoints
↥List of similar endpoints to
Hypertrophic scar
based on the number of shared cases.
Similar with more cases:
- Hypertrophic disorders of skin
- Other disorders of skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 16484 | 10557 | 5801 |
| Only index persons | 15658 | 10196 | 5462 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.25 | 0.30 | 0.16 |
| Only index persons | 0.32 | 0.37 | 0.21 |
| Median age at first event (years) | |||
| Whole population | 30.18 | 31.04 | 28.53 |
| Only index persons | 29.89 | 30.87 | 28.06 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2172 | 1605 | 567 |
| Unadjusted period prevalence (%) | 0.47 | 0.55 | 0.25 |
| Median age at first event (years) | 38.52 | 36.68 | 43.73 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1959
- Matched controls
- 19588
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L91.0
ICD-10 Finland
Hypertrophic scar
12237.4
323.0
1805
22
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
319.6
146.7
147
5
TQW99
NOMESCO Finland
Other minor procedure on skin
10.7
118.9
241
254
70130
ICD-8 Finland
Other hypertrophic and atrophic conditions of the skin, Keloid scar
+∞
113.7
108
*
QAE20
NOMESCO Finland
Excision and repair of scar or web of skin of head or neck
128.9
113.4
121
10
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
38.2
95.5
122
34
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.4
75.3
242
495
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
5.3
74.8
245
512
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.6
65.3
245
589
7014B
ICD-9 Finland
Other hypertrophic and atrophic conditions of skin, Keloid scar[CICATRIX HYPERTROPHICA]
+∞
58.6
56
*
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
15.6
50.6
84
56
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.8
35.5
246
947
S18
ICPC
Laceration/cut
1.9
35.1
744
4803
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
8.9
33.2
72
84
QBE30
NOMESCO Finland
Excision and repair of surgical scar in trunk
15.4
32.7
54
36
DAB00
NOMESCO Finland
Excision of lesion of auricle
18.9
31.4
48
26
N02AX02
ATC
tramadol; systemic, rectal
1.8
30.9
727
4809
QDE20
NOMESCO Finland
Excision and repair of scar or web of skin of lower limb
86.5
30.8
34
*
L90.6
ICD-10 Finland
Striae atrophicae
307.0
29.9
30
*
ZZR00
NOMESCO Finland
Flap of skin
8.5
29.8
66
80
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
5.8
27.8
80
142
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
30.5
27.2
36
12
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
26.6
504
3066
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
15.7
26.4
43
28
QAA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of head or neck
23.5
26.1
37
16
QCE20
NOMESCO Finland
Excision and repair of scar or web of skin of upper limb
60.9
26.0
30
5
SPAT1153
SPAT
Removal of sutures
1.8
25.8
556
3526
ZZA00
NOMESCO Finland
Split skin graft
6.4
25.3
67
107
-
ICD-10 Finland
NA
5.6
25.2
75
139
ZXC12
NOMESCO Finland
Pulse colorlaser
23.7
24.8
35
15
ZXA00
NOMESCO Finland
Right side
1.9
24.5
442
2632
9734
FHL
Excision and local plastic or associated free skin grafting
13.9
24.1
41
30
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
4.8
23.4
80
174
J01DB01
ATC
cefalexin; oral
1.8
23.3
1569
13616
D07AD01
ATC
clobetasol; topical
2.1
22.8
279
1426
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
3.4
22.5
112
342
R4120
NOMESCO Finland
Occupational therapy
2.9
22.1
141
510
J01DA01
ATC
[U] cefalexin; systemic
1.6
21.8
1177
9507
L91.9
ICD-10 Finland
Hypertrophic disorder of skin, unspecified
81.1
21.7
24
*
ZXC50
NOMESCO Finland
Cryotherapy
6.1
21.4
59
100
N02BE01
ATC
paracetamol; systemic, rectal
1.7
21.0
1599
14077
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
20.9
456
2872
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
3.6
20.9
97
280
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.7
20.9
150
584
ZXA05
NOMESCO Finland
Left side
1.8
20.9
398
2401
L91.8
ICD-10 Finland
Other hypertrophic disorders of skin
37.6
20.8
26
7
TQX05
NOMESCO Finland
Skin puncture, unspecified location
30.4
20.6
27
9
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
5.8
20.5
58
102
J01FF01
ATC
clindamycin; systemic
1.7
20.0
490
3192
QBA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of trunk
58.1
19.9
23
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
19.9
706
5089
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
19.7
396
2423
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.0
19.5
113
386
QAE30
NOMESCO Finland
Excision and repair of surgical scar in head or neck
46.5
19.2
23
5
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.6
19.2
88
252
XQ848
NOMESCO Finland
Dermatological photography
4.8
18.9
64
138
QBA50
NOMESCO Finland
Cryotherapy of skin of trunk
55.6
18.9
22
*
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
5.5
18.8
56
105
N03AX12
ATC
gabapentin; oral
2.0
18.3
267
1460
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.7
18.2
125
476
N62
ICD-10 Finland
Hypertrophy of breast
2.8
18.0
118
435
L82
ICD-10 Finland
Seborrhoeic keratosis
2.1
17.9
213
1072
N06AX11
ATC
mirtazapine; oral
1.6
17.5
568
3972
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
17.3
641
4627
ZQX00
NOMESCO Finland
0-4% of the skin
40.4
16.3
20
5
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.9
16.0
260
1471
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
5.5
15.7
46
85
TQB05
NOMESCO Finland
Puncture of skin of trunk
7.2
15.5
37
52
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
4.5
15.5
55
126
N05AH04
ATC
quetiapine; oral
1.7
15.3
323
1992
UJF32
NOMESCO Finland
Coloscopy
1.7
15.2
375
2422
9733
FHL
Excision of skin change in operating room or anesthesia
6.0
15.1
41
69
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.6
15.0
68
194
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
14.9
224
1233
N03AX16
ATC
pregabalin; oral
1.7
14.9
381
2487
L57.0
ICD-10 Finland
Actinic keratosis
2.5
14.8
117
482
J01MA02
ATC
ciprofloxacin; systemic
1.5
14.8
599
4380
L70.0
ICD-10 Finland
Acne vulgaris
2.8
14.8
95
347
WX110
NOMESCO Finland
Local anesthesy
1.5
14.7
1326
11468
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.4
14.5
129
565
M79.6
ICD-10 Finland
Pain in limb
1.5
14.4
607
4472
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
14.3
228
1283
Z42.2
ICD-10 Finland
Follow-up care involving plastic surgery of other parts of trunk
19.3
14.2
21
11
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
4.5
14.1
49
110
J01EA01
ATC
trimethoprim; systemic
1.6
14.1
460
3194
M54.5
ICD-10 Finland
Low back pain
1.5
13.9
602
4457
C03CA01
ATC
furosemide; systemic
1.7
13.8
309
1933
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
13.7
303
1894
E0000UV
ATC
NA
1.5
13.6
721
5565
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
14.8
13.6
22
15
D23.2
ICD-10 Finland
Benign neoplasm: Skin of ear and external auricular canal
7.2
13.5
32
45
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
4.5
13.5
47
106
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
13.5
317
2012
A02BC05
ATC
esomeprazole; systemic
1.5
13.5
657
4982
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
13.4
592
4396
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
13.1
469
3318
B01AB05
ATC
enoxaparin; parenteral
1.6
13.1
441
3080
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
8.8
13.0
27
31
SPAT1301
SPAT
No procedures
1.5
12.9
539
3949
X58
ICD-10 Finland
Exposure to other specified factors
1.8
12.9
244
1452
A02BC02
ATC
pantoprazole; systemic
1.4
12.8
1060
8884
ZXA10
NOMESCO Finland
Bilateral
1.7
12.7
294
1857
XQ845
NOMESCO Finland
Dermatoscopy
6.8
12.7
31
46
J02AC01
ATC
fluconazole; systemic
1.4
12.6
767
6063
S97
ICPC
Chronic ulcer skin
3.1
12.6
68
224
N06AB04
ATC
citalopram; systemic
1.6
12.4
362
2431
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
12.4
557
4139
R51.80
ICD-10 Finland
Headache
1.7
12.3
301
1931
R4110
NOMESCO Finland
Physiotherapy
1.6
12.1
409
2845
ZQZ00
NOMESCO Finland
Treatment of several skin areas
18.2
12.0
18
10
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
12.0
365
2479
S29
ICPC
Skin symptom/complaint other
1.7
12.0
275
1732
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
11.9
307
1997
WX002
NOMESCO Finland
Sedation and analgesia
1.7
11.8
293
1885
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
11.7
369
2524
TQW80
NOMESCO Finland
Local dermatologic skincare
3.6
11.7
51
143
N05CF01
ATC
zopiclone; oral
1.5
11.6
472
3422
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
11.6
773
6184
N02AA05
ATC
oxycodone; systemic
1.9
11.5
182
1019
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
8.7
11.5
24
28
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
10.1
11.5
22
22
QCE30
NOMESCO Finland
Excision and repair of surgical scar in upper limb
120.7
11.4
12
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
2.7
11.4
79
303
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.5
11.4
489
3586
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
10.6
11.3
21
20
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.2
11.3
113
526
AA1AD
NOMESCO Finland
CT of head and brain
1.6
11.2
309
2045
Z42.0
ICD-10 Finland
Follow-up care involving plastic surgery of head and neck
25.2
11.1
15
6
J01MA12
ATC
levofloxacin; systemic
1.7
11.1
257
1620
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.8
11.1
193
1118
ZZF00
NOMESCO Finland
Graft of adipose tissue
5.1
11.1
34
68
N05CF02
ATC
zolpidem; oral
1.6
11.1
302
1994
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
11.0
640
4978
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.7
11.0
74
281
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
11.0
172
961
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
3.2
10.9
57
184
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
10.9
436
3146
QDE35
NOMESCO Finland
Repair of skin defect in lower limb after surgery or injury
15.6
10.8
17
11
DAW99
NOMESCO Finland
Other operation on auricle
28.2
10.7
14
5
P01AB01
ATC
metronidazole; oral, rectal
1.4
10.7
688
5446
Z00.0
ICD-10 Finland
General medical examination
1.6
10.6
316
2128
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
4.1
10.4
39
96
N06AB06
ATC
sertraline; oral
1.7
10.4
215
1311
A02BC03
ATC
lansoprazole; oral
1.5
10.4
429
3115
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
10.4
213
1296
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
10.3
445
3256
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
10.3
925
7744
ZXC10
NOMESCO Finland
Use of laser
3.5
10.3
47
138
WX702
NOMESCO Finland
Supraglottic ventilation device
2.3
10.2
93
414
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
10.2
248
1584
L89
ICD-10 Finland
Decubitus ulcer and pressure area
13.2
10.2
17
13
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
10.1
156
867
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
10.1
581
4501
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
2.3
10.0
90
401
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
2.1
10.0
118
590
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
9.9
261
1703
C07AB07
ATC
bisoprolol; oral
1.4
9.9
593
4621
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.3
9.8
89
398
R06.0
ICD-10 Finland
Dyspnoea
1.5
9.8
346
2426
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.7
9.8
214
1328
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
9.7
366
2601
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
7.4
9.7
22
30
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
9.6
180
1065
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
9.6
732
5937
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
9.6
327
2271
D10BA01
ATC
isotretinoin; oral
1.8
9.5
160
917
J01AA07
ATC
tetracycline; systemic
1.6
9.4
292
1983
TQA05
NOMESCO Finland
Puncture of skin of head or neck
30.2
9.4
12
*
WX402
NOMESCO Finland
General anaesthesia
1.6
9.4
277
1859
QBE25
NOMESCO Finland
Excision and repair of scar of trunk caused by burn
+∞
9.4
9
*
A46
ICD-10 Finland
Erysipelas
1.8
9.4
167
973
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.1
9.3
111
557
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.0
9.3
120
624
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.9
9.3
130
697
R03AC02
ATC
salbutamol; inhalant
1.3
9.3
928
7853
R53
ICD-10 Finland
Malaise and fatigue
1.5
9.2
341
2412
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
6.1
9.2
24
40
M25.5
ICD-10 Finland
Pain in joint
1.4
9.2
487
3700
B07.9
ICD-10 Finland
Verruca simplex
2.5
9.2
67
269
J01FA06
ATC
roxithromycin; oral
1.4
9.1
666
5354
N06AX16
ATC
venlafaxine; oral
1.6
9.0
260
1734
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
3.8
9.0
37
100
QDE30
NOMESCO Finland
Excision and repair of surgical scar in lower limb
36.9
9.0
11
*
R52.9
ICD-10 Finland
Pain, unspecified
1.9
9.0
135
745
R06AE07
ATC
cetirizine; oral
1.3
9.0
811
6744
R05
ICD-10 Finland
Cough
1.5
8.9
300
2080
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.3
8.9
79
350
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.6
8.9
212
1350
M01AE01
ATC
ibuprofen; systemic, rectal
1.5
8.8
1697
15913
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
8.8
885
7469
SPAT1263
SPAT
Sampling
1.3
8.8
741
6091
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.9
8.7
123
663
WZA90
NOMESCO Finland
Other doctors statement
1.4
8.7
409
3037
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.1
8.7
95
462
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.1
8.7
32
79
N06AB10
ATC
escitalopram; oral
1.5
8.6
380
2786
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
3.1
8.6
44
142
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
3.0
8.6
47
159
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
8.6
599
4769
QBA00
NOMESCO Finland
Puncture of skin of trunk
9.0
8.5
17
19
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
8.5
280
1927
QBD20
NOMESCO Finland
Excision of burn of trunk and coverage
27.6
8.5
11
*
L17
ICPC
Foot/toe symptom/complaint
1.4
8.5
392
2900
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.3
8.4
77
347
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
5.4
8.4
24
45
Z42.9
ICD-10 Finland
Follow-up care involving plastic surgery, unspecified
90.4
8.4
9
*
L91
ICD-10 Finland
Hypertrophic disorders of skin
90.4
8.4
9
*
7014A
ICD-9 Finland
Other hypertrophic and atrophic conditions of skin, Keloid scar[CICATRIX KELOIDES]
90.4
8.4
9
*
S21
ICPC
Skin texture symptom/complaint
1.7
8.4
188
1173
A02BC01
ATC
omeprazole; systemic
1.4
8.4
401
2986
SFA00
NOMESCO Finland
Small filling
1.6
8.4
222
1452
QB001
NOMESCO Finland
Local radiotherapy of skin of trunk
+∞
8.3
8
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
8.3
293
2046
QBA99
NOMESCO Finland
Other local destruction of skin of trunk
8.6
8.3
17
20
J05AB11
ATC
valaciclovir; oral
1.6
8.3
206
1325
SDA02
NOMESCO Finland
Parodonthologic therapy
1.4
8.2
579
4610
J01AA02
ATC
doxycycline; systemic
1.3
8.2
1318
11870
D07AC01
ATC
betamethasone; topical
1.4
8.2
529
4149
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.4
8.2
66
279
J01CA04
ATC
amoxicillin; systemic
1.4
8.1
1533
14154
HAD99
NOMESCO Finland
Other plastic operation on breast
5.4
8.1
23
43
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.8
8.1
149
877
TQW40
NOMESCO Finland
Remowal of suture of skin
1.9
8.1
110
583
L84
ICD-10 Finland
Corns and callosities
3.2
8.1
41
132
QDA10
NOMESCO Finland
Incision of skin of lower limb
8.2
8.1
17
21
R42
ICD-10 Finland
Dizziness and giddiness
1.5
8.1
304
2153
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.8
8.0
134
766
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
8.0
718
5931
R01AD09
ATC
mometasone; nasal
1.3
8.0
814
6853
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.7
8.0
158
951
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
1.8
8.0
141
821
R05FB02
ATC
cough suppressants and expectorants
1.4
7.9
546
4328
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
7.9
1244
11138
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
7.9
1325
11974
N06AX21
ATC
duloxetine; oral
1.6
7.9
185
1172
F45.8
ICD-10 Finland
Other somatoform disorders
1.7
7.9
147
870
WF099
NOMESCO Finland
Other radiotherapy
7.8
7.9
17
22
E66.01
ICD-10 Finland
Obesity due to excess calories
1.7
7.9
152
910
J01CF02
ATC
cloxacillin; systemic
3.1
7.9
41
135
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.1
7.8
89
440
G47.3
ICD-10 Finland
Sleep apnoea
1.5
7.8
279
1956
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
10.8
7.8
14
13
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
1.7
7.8
168
1041
L03
ICPC
Low back symptom/complaint
1.4
7.8
408
3086
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
7.8
153
923
G44.2
ICD-10 Finland
Tension-type headache
1.5
7.7
243
1653
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.8
7.7
133
768
R50.9
ICD-10 Finland
Fever, unspecified
1.6
7.6
219
1460
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.0
7.6
88
441
XQ800
NOMESCO Finland
Prick test
1.7
7.6
146
871
K07.60
ICD-10 Finland
Snapping jaw
1.9
7.6
106
569
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.0
7.6
88
443
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
7.5
209
1382
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
7.5
184
1177
F51.0
ICD-10 Finland
Nonorganic insomnia
1.5
7.5
242
1659
L04AA01
ATC
[U] ciclosporin; systemic
4.1
7.5
27
66
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
3.1
7.5
39
129
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.6
7.5
196
1279
H02AB06
ATC
prednisolone; systemic
1.3
7.4
719
5989
T95.1
ICD-10 Finland
Sequelae of burn, corrosion and frostbite of trunk
80.4
7.4
8
*
C10AA01
ATC
simvastatin; oral
1.4
7.3
452
3511
AN1
HP
Coronary angiography
1.8
7.3
111
616
M01AE02
ATC
naproxen; oral, rectal
1.3
7.2
1013
8870
I20.09
ICD-10 Finland
Unstable angina
2.4
7.2
57
239
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
7.2
138
826
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
3.4
7.2
32
94
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
3.6
7.2
30
84
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.3
7.2
63
281
ZZS45
NOMESCO Finland
Z-plasty
30.1
7.1
9
*
QBJ30
NOMESCO Finland
Correction of abdominal apron
4.4
7.1
24
55
K59.09
ICD-10 Finland
Constipation, unspecified
2.0
7.1
82
411
C03DA01
ATC
spironolactone; oral
1.8
7.1
119
682
127
Kela drug reimbursment
Transplant complication
4.0
7.1
26
65
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.2
7.1
67
308
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
2.7
7.0
46
175
C07AA05
ATC
propranolol; systemic
1.4
7.0
332
2456
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.0
7.0
83
418
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
2.9
7.0
40
138
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.9
7.0
99
536
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
6.9
409
3151
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
6.9
217
1477
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
6.9
221
1509
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
6.9
153
952
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
6.9
451
3529
SPAT1260
SPAT
Consultation of another employee
1.5
6.9
276
1979
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.0
6.9
86
444
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
6.8
319
2356
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.5
6.8
244
1709
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.9
6.8
98
534
E000001
ATC
NA
1.4
6.8
347
2607
BAA60
NOMESCO Finland
Total thyroidectomy
2.6
6.8
48
191
R20.2
ICD-10 Finland
Paraesthesia of skin
1.8
6.8
111
632
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.3
6.8
60
268
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
6.7
167
1071
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.8
6.7
118
689
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.4
6.7
325
2415
Z71.8
ICD-10 Finland
Other specified counselling
1.4
6.7
419
3258
N05BA12
ATC
alprazolam; oral
1.6
6.7
156
988
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
6.7
168
1083
J31.0
ICD-10 Finland
Chronic rhinitis
1.7
6.7
126
751
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
3.9
6.7
25
64
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
22.6
6.7
9
*
Z42.3
ICD-10 Finland
Follow-up care involving plastic surgery of upper extremity
22.6
6.7
9
*
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
6.6
982
8620
A01
ICPC
Pain general/multiple sites
1.8
6.6
117
684
D23.6
ICD-10 Finland
Benign neoplasm: Skin of upper limb, including shoulder
5.2
6.6
19
37
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.4
6.6
443
3479
A03FA02
ATC
cisapride; oral, rectal
1.9
6.6
100
553
A06AD11
ATC
lactulose; oral
1.6
6.6
167
1080
M01AC06
ATC
meloxicam; systemic, rectal
1.3
6.6
534
4323
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
8.7
6.5
13
15
XF402
NOMESCO Finland
ECG with work load test
1.7
6.5
133
812
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
6.5
255
1818
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.7
6.5
123
735
DHB00
NOMESCO Finland
Excision of lesion of external nose
5.0
6.5
19
38
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.4
6.5
380
2921
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.0
6.5
75
379
N05BA04
ATC
oxazepam; oral
1.4
6.4
389
3005
8720/3-C44.7
ICD-O-3
Malignant melanoma, NOS, of skin of lower limb and hip
7.4
6.4
14
19
K30
ICD-10 Finland
Functional dyspepsia
1.6
6.4
159
1024
R06AX27
ATC
desloratadine; oral
1.3
6.4
495
3978
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
3.3
6.4
29
88
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.5
6.3
224
1564
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
6.3
967
8504
T88.8
ICD-10 Finland
Other specified complications of surgical and medical care, not elsewhere classified
6.6
6.3
15
23
M24.8
ICD-10 Finland
Other specific joint derangements, not elsewhere classified
5.2
6.3
18
35
K59.0
ICD-10 Finland
Constipation
2.0
6.3
76
390
QAE50
NOMESCO Finland
Dermabrasion of superficial lesion of skin of head or neck
18.1
6.3
9
5
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
2.7
6.3
38
140
L85.89
ICD-10 Finland
Other specified epidermal thickening
+∞
6.3
6
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
6.3
199
1359
N05CD07
ATC
temazepam; oral
1.7
6.2
135
835
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
2.1
6.2
64
307
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
6.2
409
3204
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.6
6.2
42
165
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.5
6.2
181
1212
M02AA07
ATC
piroxicam; topical
1.3
6.2
495
3995
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
6.2
121
729
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
6.2
456
3636
M03BX02
ATC
tizanidine; oral
1.3
6.1
1068
9524
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
2.7
6.1
38
142
A01AB09
ATC
miconazole; local oral
1.7
6.1
126
771
R52.2
ICD-10 Finland
Other chronic pain
2.2
6.1
58
267
NBG10
NOMESCO Finland
Acromioplastia
2.9
6.1
35
122
D19
ICPC
Teeth/gum symptom/complaint
1.3
6.1
456
3638
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
2.0
6.1
70
353
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.6
6.1
169
1117
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
6.1
188
1275
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
8.6
6.1
12
14
D11
ICPC
Diarrhoea
1.5
6.0
205
1420
WX320
NOMESCO Finland
Spinalanesthesy
1.4
6.0
309
2322
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
2.0
6.0
69
346
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1002
7512
1.62
25.95
6.3
6.0
1.2
1.2
mmol/l
0.27
885
6327
1264
10068
1.61
25.13
8.1
8.5
4.0
4.0
e9/l
0.25
1136
8832
911
6782
1.59
23.57
6.1
5.4
1.2
1.2
mmol/l
0.51
846
6168
879
6526
1.58
22.78
4.9
4.4
36.7
36.4
g/l
0.89
835
6082
713
5072
1.60
21.96
2.7
2.4
54.7
56.9
u/l
0.86
664
4692
1511
12760
1.61
21.86
7.7
6.7
78.2
75.6
u/l
0.84
1458
12007
1061
8274
1.55
21.83
5.7
5.6
10.5
10.6
umol/l
0.07
995
7797
940
7191
1.54
20.74
2.5
2.2
76.6
74.9
nmol/l
1.02
881
6594
1169
9399
1.53
20.32
5.0
4.3
6.6
6.4
mmol/l
1.09
1090
8607
1958
18025
1.88
16.98
14.1
11.3
21.3
20.9
mg/l
0.24
1594
13947
1492
12872
1.51
16.85
4.4
3.7
10.9
10.5
mm/h
0.73
1416
11984
713
5323
1.51
16.65
2.8
3.1
2.4
2.4
mmol/l
0.45
648
4740
1084
8825
1.46
16.15
3.6
3.3
0.0
0.0
estimate
0.78
205
1690
1926
17742
1.76
15.30
15.6
12.1
139.6
139.6
mmol/l
0.28
1900
17247
1631
14450
1.52
15.22
4.9
4.1
14.5
14.5
pmol/l
0.17
1532
13352
1930
17795
1.76
15.20
15.5
12.2
3.9
3.9
mmol/l
0.36
1901
17268
600
4395
1.50
15.07
2.5
2.1
180.5
215.0
u/l
0.56
572
4164
720
5475
1.47
15.00
3.3
3.0
294.7
42.9
ng/l
0.67
418
3108
1068
8749
1.43
14.93
4.8
4.5
0.0
0.0
estimate
0.50
202
1739
183
999
1.91
14.17
2.5
2.2
12.1
7.4
ug/l
0.50
163
887
1059
8726
1.42
13.98
3.5
3.3
0.0
0.0
estimate
0.50
197
1693
1009
8247
1.42
13.92
3.9
3.9
—
—
—
0
0
389
2660
1.56
13.22
2.5
2.7
2.4
2.4
mmol/l
0.06
350
2338
1343
11602
1.41
13.14
4.7
4.0
1251.5
1713.0
e6/l
—
10
136
1027
8497
1.40
12.82
6.0
5.5
56.6
56.4
%
0.18
984
7980
518
3800
1.48
12.57
3.6
3.6
1.0
1.0
kg/l
0.03
69
563
774
6123
1.41
12.46
1.9
1.8
97.3
97.0
pmol/l
0.06
385
3246
284
1830
1.63
12.34
5.4
5.2
1.1
1.0
mmol/l
0.94
274
1697
1036
8619
1.39
12.33
6.1
5.7
29.4
29.3
%
0.17
985
8074
472
3419
1.49
12.15
3.0
2.9
1393.8
970.8
ng/l
0.61
385
2818
1685
15261
1.46
12.01
5.5
4.7
38.7
38.4
mmol/mol
0.43
1621
14302
1817
16753
1.52
11.41
5.7
4.7
1.8
2.0
mu/l
1.18
1731
15648
172
990
1.80
11.26
3.1
2.8
175.8
159.0
ng/l
0.23
149
889
732
5813
1.39
11.25
3.5
3.0
30.5
30.0
u/l
0.10
697
5534
526
3962
1.43
10.89
1.9
1.7
0.9
1.0
mg/l
0.26
394
2919
834
6798
1.37
10.81
3.6
3.3
—
—
—
0
0
2010
19032
1.75
10.70
10.8
8.9
26.2
25.6
u/l
0.68
1962
18447
82
372
2.25
10.48
1.5
1.4
19.2
22.0
u/l
0.42
67
316
144
806
1.84
10.33
11.1
7.6
24.4
24.4
mmol/l
0.01
134
751
195
1198
1.69
10.15
2.2
2.4
73.3
73.2
ml/min/173m2
0.00
74
449
204
1270
1.67
10.10
3.9
3.3
4.5
4.6
pmol/l
0.11
185
1135
240
1559
1.61
10.03
22.8
20.1
1.2
1.2
inr
0.03
47
229
382
2747
1.47
10.02
4.2
3.3
270.5
457.9
ng/l
1.28
248
1806
265
1764
1.57
9.99
7.3
5.6
—
—
—
0
0
91
444
2.10
9.72
1.5
1.4
304.2
302.9
ug/g
0.02
55
232
197
1228
1.66
9.70
8.3
8.8
121.8
122.0
g/l
0.04
190
1184
520
3980
1.40
9.68
2.3
2.1
—
—
—
0
0
1034
8826
1.33
9.44
3.3
2.7
80.7
89.5
ug/l
1.17
965
8266
333
2357
1.49
9.42
3.7
3.4
0.8
0.8
mmol/l
0.54
310
2215
109
582
1.92
9.07
3.2
3.0
25.4
25.2
mmol/l
0.20
104
559
225
1482
1.58
8.86
3.1
4.1
233.7
245.6
u/l
0.44
213
1407
140
816
1.76
8.81
9.9
9.2
1.5
1.4
%
0.71
140
809
90
455
2.02
8.76
7.8
3.7
1.3
1.4
mmol/l
0.64
90
447
225
1494
1.56
8.55
7.7
7.9
5.0
5.1
kpa
0.87
216
1423
225
1495
1.56
8.53
7.7
7.9
12.9
12.8
kpa
0.08
216
1427
320
2292
1.46
8.48
1.8
1.7
—
—
—
0
0
139
818
1.75
8.47
10.0
9.3
0.8
0.7
%
1.48
139
812
223
1485
1.56
8.37
7.8
8.0
0.7
1.0
mmol/l
0.56
167
1148
350
2558
1.44
8.33
2.4
2.5
121.3
105.5
ug/g
0.41
270
2008
179
1136
1.63
8.22
7.0
7.0
8.3
8.2
mmol/l
0.04
173
1090
580
4634
1.34
8.04
1.4
1.3
1.2
1.5
u/ml
0.50
180
1271
1771
16524
1.39
7.93
3.9
3.4
1.3
1.3
mmol/l
1.00
1679
15427
580
4652
1.34
7.80
3.8
3.5
0.0
0.0
estimate
1.28
198
1701
170
1081
1.62
7.76
3.8
3.7
87.8
77.0
ng/l
0.48
150
956
1384
12483
1.30
7.68
3.5
2.9
40.3
39.6
u/l
0.12
1313
11834
164
1041
1.62
7.54
1.5
1.6
—
—
—
0
0
187
1230
1.57
7.41
3.5
3.8
2.0
1.9
mmol/l
0.17
149
980
336
2490
1.41
7.36
1.7
1.7
1264.1
1175.3
nmol/l
0.91
260
1903
227
1561
1.51
7.35
1.8
1.7
—
—
—
0
0
2103
20414
1.95
7.09
21.4
16.7
4.5
4.5
e12/l
0.78
2074
19910
2103
20419
1.94
7.00
21.4
16.8
6.6
6.7
e9/l
0.79
2075
19904
2101
20394
1.92
6.99
21.4
16.8
259.5
260.1
e9/l
0.15
2072
19921
223
1547
1.49
6.92
1.8
1.6
—
—
—
0
0
2103
20425
1.93
6.90
21.5
16.8
135.3
135.2
g/l
0.09
2089
20172
318
2362
1.41
6.86
2.6
2.2
13.9
14.0
umol/l
0.08
299
2178
1832
17297
1.38
6.72
4.3
3.8
4.7
4.8
mmol/l
3.17
1745
16281
15
32
4.71
6.69
1.5
1.7
2.0
2.3
ug/l
—
9
11
515
4157
1.31
6.45
2.5
2.1
2.7
2.8
mg/l
0.64
461
3559
114
687
1.70
6.44
1.4
1.4
10.1
10.1
u/l
0.01
87
553
258
1873
1.43
6.32
3.0
2.6
7.0
7.1
umol/l
0.01
219
1579
418
3286
1.34
6.29
2.6
2.3
6.8
7.7
e6/l
0.51
370
2876
1755
16515
1.33
6.16
11.9
10.1
89.2
88.4
ml/min/173m2
0.79
1473
13399
429
3396
1.33
6.15
1.5
1.5
21.9
20.9
nmol/l
0.69
390
2940
196
1358
1.49
6.13
2.7
2.3
0.2
0.2
g/l
0.29
182
1275
266
1963
1.40
5.94
2.7
2.3
22.5
23.7
%
0.82
229
1680
1772
16725
1.32
5.89
4.4
3.8
5.8
5.7
mmol/l
1.56
1669
15489
286
2143
1.39
5.84
2.6
2.2
2.5
2.4
g/l
0.70
269
1985
1842
17500
1.35
5.72
4.8
4.1
2.8
2.8
mmol/l
1.77
1752
16362
114
710
1.64
5.71
1.3
1.2
1.4
1.2
u/ml
0.08
15
60
148
982
1.54
5.68
2.4
2.1
10.4
11.8
nmol/l
1.14
132
866
484
3938
1.29
5.63
2.5
2.3
3689.0
4260.8
umol/l
0.12
425
3466
1812
17201
1.32
5.45
4.3
3.8
1.5
1.5
mmol/l
1.86
1726
16114
77
438
1.79
5.37
1.9
1.6
41.8
40.9
nmol/l
0.10
77
425
91
546
1.70
5.28
1.9
2.0
1.4
1.4
g/l
0.17
76
482
498
4098
1.28
5.27
4.2
3.9
7.0
8.8
mg/mmol
0.57
323
2559
292
2233
1.36
5.24
2.6
2.1
29.3
29.3
s
0.04
284
2156
64
351
1.85
5.04
1.3
1.4
—
—
—
0
0
197
1421
1.42
5.02
2.3
2.2
7333.4
5934.7
u/l
0.19
61
576
45
221
2.06
4.88
1.2
1.2
—
—
—
0
0
86
521
1.68
4.84
2.1
1.7
1.2
1.2
g/l
1.15
81
489
225
1672
1.39
4.83
2.0
1.9
381.9
377.3
nmol/l
0.13
211
1532
86
524
1.67
4.74
3.7
6.5
1.6
1.6
%
0.09
81
488
111
721
1.57
4.73
2.0
2.1
39.0
39.6
u/l
0.10
105
657
388
3134
1.29
4.72
1.3
1.3
14.4
10.2
u/ml
0.41
154
1272
558
4712
1.25
4.68
1.7
1.6
—
—
—
0
0
1654
15605
1.25
4.66
16.6
13.8
13.5
13.5
%
0.38
1624
15267
151
1052
1.47
4.64
1.7
1.6
330.9
307.5
mu/l
0.31
138
949
175
1256
1.43
4.60
2.8
2.7
10.5
10.6
g/l
0.15
157
1153
494
4123
1.26
4.58
1.5
1.5
—
—
—
0
0
145
1005
1.47
4.57
3.0
2.6
67.2
67.1
g/l
0.04
135
929
548
4635
1.24
4.51
3.6
3.2
7.6
7.7
mmol/l
0.17
478
3957
23
87
2.66
4.49
4.3
2.7
388.0
945.6
u/ml
2.37
23
87
82
502
1.66
4.46
2.1
1.7
0.2
0.2
g/l
0.00
77
471
515
4332
1.25
4.45
3.4
2.8
0.3
0.4
e6/l
0.39
406
3216
321
2548
1.30
4.44
3.0
2.4
1.3
1.3
e6/l
0.02
195
1379
23
88
2.63
4.40
1.4
1.5
7.8
5.5
u/l
0.36
11
48
69
409
1.71
4.24
1.3
1.2
—
—
—
0
0
67
397
1.71
4.14
1.4
1.5
2.0
20.6
e6/l
2.46
50
312
67
397
1.71
4.14
1.4
1.6
19.9
954.8
e6/l
1.81
52
327
102
678
1.53
3.97
2.1
1.7
—
—
—
0
0
30
137
2.21
3.96
1.0
1.1
55.8
60.0
u/l
0.16
24
98
17
59
2.90
3.90
1.2
1.0
—
—
—
0
0
123
854
1.47
3.89
3.0
3.3
5.2
5.1
kpa
0.29
111
804
45
244
1.86
3.76
1.3
1.2
—
—
—
0
0
193
1471
1.34
3.57
2.6
2.8
1.7
1.7
%
0.41
176
1313
155
1141
1.39
3.57
1.3
1.3
40.3
38.9
au/ml
—
7
51
394
3292
1.24
3.56
1.4
1.3
25.0
27.6
iu/ml
0.16
111
1026
111
774
1.46
3.46
1.4
1.5
—
—
—
0
0
1489
14056
1.19
3.42
3.6
3.5
—
—
—
0
0
69
435
1.61
3.42
2.8
2.2
660.7
375.0
ug/l
0.36
62
402
28
133
2.12
3.40
1.5
1.5
7171.2
85088.3
e6/l
0.86
20
91
20
82
2.45
3.38
1.1
1.1
—
—
—
0
0
405
3415
1.23
3.36
2.2
2.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
21
89
2.37
3.32
1.2
1.1
—
—
—
0
0
17
65
2.63
3.30
1.1
1.2
—
—
—
0
0
47
272
1.74
3.22
3.1
3.1
34.9
33.0
umol/l
0.15
40
233
115
820
1.42
3.21
2.8
3.3
1.6
1.6
mmol/l
0.05
84
594
17
67
2.55
3.12
1.1
1.2
—
—
—
0
0
30
153
1.97
3.05
1.6
1.4
—
—
titre
—
0
0
196
1540
1.30
2.96
3.0
2.2
31.3
69.8
u/l
0.66
170
1310
52
318
1.65
2.95
3.0
3.2
9.1
8.6
kpa
1.12
47
297
15
58
2.60
2.87
1.1
1.2
—
—
—
0
0
52
321
1.64
2.85
2.4
2.9
24.6
24.9
mmol/l
0.16
46
283
162
1248
1.32
2.83
2.3
2.3
19.0
20.6
au/ml
0.08
14
97
36
201
1.80
2.82
1.5
1.4
—
—
—
0
0
440
3803
1.20
2.81
2.3
2.2
—
—
—
0
0
9
23
3.92
2.77
6.8
5.5
—
—
—
0
0
36
203
1.79
2.73
1.5
1.4
—
—
—
0
0
42
248
1.71
2.73
1.5
1.6
—
—
—
0
0
36
205
1.77
2.66
1.5
1.4
—
—
—
0
0
60
391
1.55
2.65
2.7
2.7
—
—
—
0
0
1794
17340
1.20
2.63
15.2
12.2
39.9
40.0
%
0.07
1377
13623
157
1225
1.30
2.53
1.1
1.0
—
—
—
0
0
288
2418
1.22
2.49
3.2
2.6
4.0
3.5
e6/l
0.23
159
1254
168
1328
1.29
2.46
3.4
4.3
9.6
24.2
ug/l
1.08
123
1050
165
1304
1.29
2.43
1.3
1.3
24.7
25.4
iu/l
0.10
139
1101
80
565
1.43
2.42
1.1
1.1
—
—
—
0
0
34
197
1.74
2.39
5.9
4.3
36.9
90.9
u/ml
—
10
58
32
183
1.76
2.36
1.5
1.4
315.8
325.9
pmol/l
0.08
24
137
24
125
1.93
2.35
2.0
2.4
12.2
12.2
%
0.00
15
65
61
412
1.49
2.33
2.3
2.3
7.4
5.3
umol/l
0.47
47
306
101
749
1.37
2.32
3.0
2.4
0.2
0.2
e6/l
0.50
96
723
41
253
1.63
2.31
1.5
1.4
—
—
—
0
0
162
1287
1.28
2.30
1.3
1.3
168.1
209.1
u/ml
0.50
154
1191
79
563
1.42
2.29
2.0
1.8
—
—
—
0
0
111
838
1.34
2.28
1.4
1.5
—
—
—
0
0
34
201
1.70
2.25
1.5
1.4
—
—
—
0
0
67
465
1.45
2.25
1.8
2.0
3.8
2.0
ug/l
0.43
60
410
34
202
1.69
2.21
1.5
1.4
—
—
—
0
0
78
560
1.41
2.19
1.1
1.1
—
—
—
0
0
34
203
1.69
2.18
1.5
1.4
—
—
—
0
0
35
211
1.67
2.17
1.1
1.0
—
—
—
0
0
79
571
1.40
2.14
1.3
1.6
0.0
0.2
iu/ml
1.03
19
110
27
153
1.77
2.08
1.4
1.7
—
—
—
0
0
14
62
2.27
2.07
1.0
1.4
79.2
91.9
%
—
5
31
47
309
1.53
2.06
2.0
2.1
131.3
130.5
g/l
0.09
39
230
43
277
1.56
2.06
2.2
2.2
16.3
16.5
%
0.09
23
126
77
559
1.39
2.05
3.1
2.4
96.6
93.4
%
0.67
69
519
6
15
4.01
2.04
1.2
1.1
—
—
—
0
0
252
2133
1.21
2.04
4.4
3.8
22.5
21.2
%
0.54
106
892
28
162
1.74
2.02
1.1
1.1
—
—
—
0
0
312
2698
1.18
1.99
4.7
4.3
2.0
2.5
ug/l
0.56
288
2431
487
4362
1.15
1.98
1.7
1.6
1.4
1.4
mmol/l
0.00
424
3775
19
98
1.95
1.95
1.5
1.3
16020.5
35278.6
e6/l
0.49
12
49
8
27
2.97
1.93
1.4
1.1
—
—
—
0
0
6
16
3.76
1.93
1.5
1.2
6.5
23.4
%
—
6
11
6
16
3.76
1.93
1.2
1.1
—
—
—
0
0
91
686
1.34
1.93
1.3
1.4
—
—
—
0
0
14
65
2.16
1.88
1.0
1.1
86.0
90.5
%
—
5
33
285
2459
1.18
1.87
1.9
1.8
1.4
1.4
%
0.45
260
2205
8
28
2.86
1.86
1.4
1.1
—
—
—
0
0
23
129
1.79
1.85
1.7
1.2
—
—
—
0
0
72
527
1.38
1.85
2.0
2.0
4.9
5.0
iu/l
0.02
24
204
11
46
2.40
1.85
1.1
1.1
—
—
—
0
0
11
46
2.40
1.85
1.0
1.1
—
—
—
0
0
11
46
2.40
1.85
1.1
1.1
104.9
96.2
%
0.76
11
46
80
596
1.36
1.84
1.2
1.1
4.6
3.1
u/ml
—
5
86
6
17
3.54
1.84
1.3
1.4
61.8
99.6
ng/l
—
6
17
50
343
1.47
1.83
1.9
1.8
8553.8
11513.5
e6/l
0.25
37
253
25
145
1.73
1.81
1.1
1.1
—
—
—
0
0
25
145
1.73
1.81
1.1
1.1
—
—
—
0
0
13
60
2.17
1.77
1.3
1.1
23.8
326.1
ng/l
—
5
11
25
146
1.72
1.77
1.1
1.1
—
—
—
0
0
23
131
1.76
1.77
1.7
1.2
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
52
365
1.44
1.71
3.0
3.5
0.3
0.4
u/ml
0.97
31
192
61
441
1.39
1.71
1.4
1.5
0.4
0.4
nmol/l
0.14
44
355
21
118
1.79
1.70
2.3
2.4
—
—
—
0
0
30
187
1.61
1.69
1.4
1.4
—
—
—
0
0
34
219
1.56
1.68
1.3
1.4
—
—
—
0
0
80
607
1.33
1.66
1.9
1.8
—
—
—
0
0
50
351
1.43
1.65
1.3
1.2
—
—
—
0
0
7
25
2.81
1.65
1.1
1.4
—
—
—
0
0
40
269
1.50
1.64
1.2
1.6
—
—
—
0
0
73
548
1.34
1.63
2.0
1.7
—
—
—
0
0
58
420
1.39
1.62
2.8
2.0
10.3
10.4
g/l
0.04
53
366
21
120
1.76
1.62
2.3
2.9
641.5
497.6
e6/l
0.78
16
103
5
14
3.58
1.61
2.0
2.2
—
—
—
0
0
15
77
1.95
1.59
1.2
2.0
—
—
—
0
0
27
167
1.62
1.58
2.9
2.1
37.3
25.6
mg/l
—
7
48
49
346
1.43
1.58
1.2
1.2
1.2
4.3
u/ml
—
7
30
48
338
1.43
1.57
2.7
3.4
2.3
1.6
ratio
—
5
35
20
114
1.76
1.56
1.6
1.3
387.7
1877.8
e6/l
5.47
15
72
24
145
1.66
1.54
1.1
1.1
—
—
—
0
0
24
145
1.66
1.54
1.1
1.1
—
—
—
0
0
49
348
1.42
1.54
2.8
3.5
26.6
43.0
mg/l
1.01
40
282
49
348
1.42
1.54
2.8
3.5
36.2
64.8
mg/l
0.88
40
282
364
3252
1.14
1.54
1.7
1.6
52215651.6
30018448.0
pmol/l
0.24
316
2775
179
1513
1.20
1.52
2.5
2.9
—
—
—
0
0
189
1606
1.19
1.51
1.3
1.2
139.4
151.7
iu/ml
0.15
74
606
29
185
1.58
1.51
1.3
1.4
—
—
—
0
0
13
65
2.01
1.48
1.0
1.0
885.9
726.6
ng/l
—
7
41
13
65
2.01
1.48
1.0
1.0
130.3
289.6
ng/l
—
7
41
68
514
1.33
1.48
3.6
2.6
178.0
173.3
%
0.18
63
498
49
351
1.41
1.48
1.5
1.5
—
—
—
0
0
62
463
1.35
1.46
1.6
1.6
—
—
—
0
0
6
22
2.73
1.43
1.2
1.0
—
—
—
0
0
13
66
1.98
1.43
1.0
1.0
13.7
41.7
ng/l
—
7
40
61
457
1.34
1.42
2.7
2.0
3.9
3.7
g/l
0.35
46
343
61
458
1.34
1.40
2.7
2.0
—
—
—
0
0
61
458
1.34
1.40
2.7
2.0
7.2
7.4
g/l
0.41
48
362
44
315
1.41
1.35
5.8
5.0
3208.4
320.3
iu/ml
—
5
36
117
961
1.23
1.35
1.8
1.8
—
—
—
0
0
26
167
1.56
1.34
2.0
1.5
—
—
—
0
0
14
75
1.87
1.34
1.3
1.3
—
19.1
—
0
13
12
61
1.97
1.32
1.2
1.1
—
—
—
0
0
19
114
1.67
1.28
1.0
1.1
4.2
4.0
nmol/l
—
5
22
44
319
1.39
1.27
1.1
1.0
2.8
2.4
u/ml
0.17
21
156
20
122
1.65
1.27
1.4
1.5
—
—
—
0
0
20
122
1.65
1.27
1.4
1.5
—
—
—
0
0
20
122
1.65
1.27
1.4
1.5
—
—
—
0
0
35
244
1.44
1.25
3.2
2.7
7.2
7.1
mmol/l
0.04
35
235
55
415
1.33
1.25
1.4
1.3
246.3
227.5
u/ml
0.19
39
249
39
279
1.41
1.22
1.2
1.3
—
—
—
0
0
39
279
1.41
1.22
1.2
1.3
—
—
—
0
0
57
434
1.32
1.22
1.4
1.2
—
—
—
0
0
49
365
1.35
1.21
2.6
1.9
37.4
37.9
g/l
0.23
44
328
60
461
1.31
1.21
1.2
1.2
3.3
8.2
u/ml
0.90
13
77
16
93
1.73
1.21
1.1
1.3
—
71.5
%
—
0
13
26
172
1.52
1.20
1.3
1.2
52.2
38.8
mg/l
0.41
21
140
23
148
1.56
1.20
1.4
1.4
1.4
1.3
promille
0.22
15
117
23
148
1.56
1.20
2.1
1.5
—
—
—
0
0
57
436
1.32
1.19
2.8
2.0
3.1
3.1
g/l
0.17
49
349
13
71
1.84
1.19
1.8
2.1
8.5
9.8
mg/l
0.50
13
59
14
79
1.78
1.17
2.2
2.3
22.0
118.4
ug/l
0.47
14
70
37
265
1.40
1.16
3.1
2.6
1.3
1.5
mmol/l
1.01
37
253
51
386
1.33
1.15
1.4
1.4
—
—
—
0
0
54
700
0.77
1.15
1.4
1.5
—
—
—
0
0
13
72
1.81
1.15
2.2
2.4
111.7
158.9
umol/l
—
6
42
20
126
1.59
1.14
1.1
1.1
1.0
1.1
u/l
—
10
63
144
1233
1.18
1.11
2.8
3.1
1.2
1.2
mmol/l
0.72
133
1066
13
73
1.79
1.10
1.2
1.2
—
—
—
0
0
5
21
2.38
1.09
2.0
1.9
—
—
—
0
0
85
694
1.23
1.08
3.7
4.4
24.0
24.2
mmol/l
0.21
79
629
41
304
1.36
1.07
1.2
1.2
2.7
4.9
u/ml
—
7
95
13
74
1.76
1.06
1.4
1.3
—
927.1
—
0
7
10
52
1.93
1.06
1.4
1.1
—
—
—
0
0
20
129
1.56
1.05
2.3
2.7
59.3
56.2
%
0.26
11
85
58
456
1.28
1.02
1.2
1.2
2.9
2.5
u/ml
—
9
50
22
147
1.50
1.00
1.5
1.7
—
—
—
0
0
12
68
1.77
1.00
1.2
1.3
—
—
—
0
0
24
164
1.47
0.99
1.1
1.1
—
—
—
0
0
83
684
1.22
0.99
9.3
9.8
23.8
24.2
mmol/l
0.92
78
644
23
156
1.48
0.98
1.4
1.2
—
—
—
0
0
7
36
1.95
0.97
1.3
2.0
—
—
—
0
0
10
54
1.86
0.96
2.7
2.2
—
—
—
0
0
9
50
1.80
0.96
1.3
1.1
—
—
—
0
0
9
50
1.80
0.96
1.6
1.1
—
—
—
0
0
9
50
1.80
0.96
1.6
1.1
—
—
—
0
0
145
1262
1.16
0.95
1.2
1.4
—
—
—
0
0
99
835
1.19
0.94
1.4
1.6
4.1
4.3
mg/l
0.07
73
571
19
125
1.52
0.94
1.4
1.2
—
—
—
0
0
17
109
1.56
0.93
1.1
1.0
—
—
—
0
0
9
52
1.73
0.92
1.4
1.1
—
—
—
0
0
6
28
2.15
0.91
1.7
1.7
1.2
1.2
mmol/l
—
6
28
35
261
1.35
0.91
1.1
1.1
—
—
—
0
0
259
2350
1.12
0.91
2.3
1.9
—
—
—
0
0
45
349
1.30
0.90
1.6
1.5
—
—
—
0
0
71
583
1.23
0.89
1.2
1.2
—
—
—
0
0
207
1856
1.13
0.89
2.2
1.8
—
—
—
0
0
65
531
1.23
0.86
1.1
1.1
1.8
1.7
u/ml
0.01
22
221
11
64
1.72
0.86
1.3
1.9
—
—
—
0
0
11
64
1.72
0.86
1.3
1.9
—
—
—
0
0
164
1845
0.88
0.85
1.5
1.5
—
—
—
0
0
39
301
1.30
0.83
1.2
1.3
1.5
3.9
u/ml
4.28
11
128
102
876
1.17
0.82
1.3
1.3
130.9
226.1
miu/ml
3.56
48
437
58
474
1.23
0.79
3.3
3.6
49.0
2718.8
u/ml
0.70
53
409
8
48
1.67
0.78
1.3
1.3
—
—
—
0
0
33
252
1.31
0.76
3.1
3.9
160.4
1492.9
u/ml
0.73
28
237
10
59
1.70
0.75
1.2
1.3
—
—
—
0
0
73
614
1.20
0.75
1.4
1.3
—
—
—
0
0
9
53
1.70
0.75
1.1
1.2
—
—
—
0
0
9
53
1.70
0.75
1.1
1.2
—
—
—
0
0
5
24
2.09
0.74
1.6
2.6
35.2
42.2
umol/l
—
5
19
7
38
1.84
0.73
1.1
1.1
—
—
—
0
0
68
805
0.84
0.72
1.7
1.7
—
—
—
0
0
5
26
1.93
0.70
1.0
1.3
—
—
—
0
0
18
126
1.43
0.70
2.7
2.8
612.2
811.6
e6/l
—
5
50
5
27
1.85
0.68
1.4
1.8
6.1
7.1
mmol/l
—
5
14
33
260
1.27
0.64
6.3
5.8
350.7
382.5
umol/l
0.82
26
223
17
121
1.41
0.62
1.1
1.2
—
35.1
—
0
7
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
17
123
1.39
0.58
1.2
1.1
1.0
1.0
ratio
—
6
51
23
176
1.31
0.56
1.3
1.7
46.5
58.6
%
—
10
121
22
168
1.31
0.55
1.5
2.3
—
—
—
0
0
20
151
1.33
0.54
1.3
1.3
—
—
—
0
0
18
134
1.35
0.53
1.6
1.5
—
—
—
0
0
6
40
1.50
0.51
1.2
1.3
—
—
—
0
0
7
107
0.65
0.48
1.4
1.5
—
—
—
0
0
20
154
1.30
0.48
1.3
1.2
0.2
0.7
u/ml
0.81
11
56
7
47
1.49
0.47
1.3
1.4
10.0
8.4
ug/l
—
7
47
81
907
0.89
0.46
1.4
1.5
—
—
—
0
0
10
142
0.70
0.46
20.9
13.5
1031.8
834.4
nmol/l
—
10
135
42
356
1.18
0.46
1.0
1.1
9.6
4.7
u/ml
0.49
19
146
31
255
1.22
0.45
1.9
1.4
—
—
—
0
0
5
85
0.59
0.45
1.6
1.4
—
—
—
0
0
7
50
1.40
0.45
2.0
2.3
250.4
53.6
ug/l
—
7
50
7
51
1.37
0.44
1.1
2.1
14.0
16.7
umol/l
—
7
51
13
95
1.37
0.43
1.5
1.3
76.9
54.0
pmol/l
—
7
30
36
303
1.19
0.43
1.0
1.1
—
—
—
0
0
5
32
1.56
0.42
1.4
1.3
—
—
—
0
0
19
149
1.28
0.41
2.1
3.6
30.5
32.7
mu/l
0.08
19
144
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.5
—
4.1
—
0
16
15
114
1.32
0.40
1.1
1.2
—
2.0
—
0
10
16
123
1.30
0.40
1.2
1.6
39.7
33.3
%
0.34
11
77
26
214
1.22
0.39
2.7
3.2
2.2
1.4
%
0.44
17
170
5
36
1.39
0.38
1.2
1.6
—
—
—
0
0
97
886
1.10
0.38
1.5
1.4
—
—
—
0
0
36
308
1.17
0.37
1.2
1.4
6.4
7.0
mmol/l
0.50
28
216
10
72
1.39
0.37
1.4
1.6
—
—
—
0
0
10
72
1.39
0.37
1.4
1.6
—
—
—
0
0
10
72
1.39
0.37
1.4
1.6
—
—
—
0
0
10
72
1.39
0.37
1.4
1.6
—
—
—
0
0
38
328
1.16
0.36
1.2
1.1
—
—
—
0
0
16
126
1.27
0.35
1.5
1.4
1.8
1.9
mmol/l
0.31
16
120
6
44
1.36
0.34
1.5
2.3
—
—
—
0
0
11
82
1.34
0.34
1.0
1.0
—
—
—
0
0
23
191
1.21
0.33
1.0
1.0
—
—
—
0
0
189
1997
0.94
0.33
1.7
1.6
—
—
—
0
0
24
201
1.20
0.32
1.3
1.4
12.4
12.6
mmol/l
—
7
35
29
248
1.17
0.31
1.7
1.6
—
—
—
0
0
36
411
0.87
0.31
1.5
1.8
—
—
—
0
0
7
99
0.71
0.30
1.1
1.2
—
—
—
0
0
16
129
1.24
0.30
1.2
1.5
—
—
—
0
0
13
102
1.28
0.30
2.4
1.6
2.3
3.5
mg/l
1.91
13
97
45
402
1.12
0.28
1.8
1.7
—
—
—
0
0
10
76
1.32
0.28
1.4
1.2
—
—
—
0
0
20
168
1.19
0.27
1.2
1.2
—
—
—
0
0
28
243
1.15
0.27
1.4
1.5
—
—
—
0
0
99
1059
0.93
0.26
1.5
1.5
—
—
—
0
0
35
310
1.13
0.26
2.5
2.4
147.4
119.1
ug/min
0.12
22
196
51
463
1.10
0.25
1.1
1.1
2.1
2.4
u/ml
0.12
15
108
88
821
1.07
0.25
1.7
2.0
—
—
—
0
0
40
359
1.12
0.24
1.5
1.4
102.6
103.2
u/ml
—
7
67
83
890
0.93
0.24
1.5
1.5
—
—
—
0
0
24
208
1.16
0.24
1.3
1.1
—
—
—
0
0
10
79
1.27
0.22
2.2
1.6
—
772331.3
—
0
8
0
11
0.00
0.21
0.0
6.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
26
230
1.13
0.20
3.6
2.5
4.0
23.5
u/ml
0.55
26
204
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
116
1217
0.95
0.19
1.4
1.4
—
—
—
0
0
33
299
1.11
0.18
1.4
1.1
200682.3
1729.9
iu/ml
0.46
11
76
7
59
1.19
0.18
1.0
1.2
—
—
—
0
0
7
60
1.17
0.17
2.0
4.6
—
—
—
0
0
31
341
0.91
0.17
2.3
3.3
3.3
4.0
e9/l
3.50
31
341
18
157
1.15
0.17
1.4
1.8
32.5
32.1
pg
0.14
18
157
42
388
1.08
0.17
1.0
1.1
1.3
4.4
u/ml
2.80
16
149
46
427
1.08
0.16
1.2
1.2
—
—
—
0
0
8
70
1.14
0.16
1.1
1.1
116.3
106.3
%
—
8
61
30
273
1.10
0.16
1.4
1.6
7.2
7.5
mmol/l
0.53
21
166
6
76
0.79
0.15
1.2
1.1
162.2
173.9
iu/ml
—
6
76
92
963
0.95
0.15
1.5
1.4
—
—
—
0
0
193
1876
1.03
0.14
3.8
3.8
32.6
32.2
%
0.15
142
1322
17
191
0.89
0.13
1.0
1.1
—
—
—
0
0
8
98
0.82
0.13
1.8
1.9
—
—
—
0
0
13
149
0.87
0.13
1.1
1.0
—
—
—
0
0
11
94
1.17
0.13
1.5
1.1
1444.5
1624.6
miu/ml
0.23
11
94
33
355
0.93
0.12
2.9
3.1
19.4
23.5
mg/l
0.41
17
220
93
967
0.96
0.12
1.5
1.4
—
—
—
0
0
93
966
0.96
0.12
1.5
1.4
—
—
—
0
0
93
966
0.96
0.12
1.5
1.4
—
—
—
0
0
22
201
1.10
0.11
3.3
3.2
0.7
0.8
nmol/l
1.06
15
160
39
367
1.06
0.11
1.2
1.3
—
—
—
0
0
17
187
0.91
0.10
1.1
1.4
—
—
—
0
0
5
46
1.09
0.09
1.2
1.1
—
—
—
0
0
35
330
1.06
0.09
1.0
1.1
—
—
—
0
0
33
349
0.94
0.08
2.5
3.5
54.0
56.5
%
0.85
33
349
12
107
1.12
0.08
1.6
1.6
—
—
—
0
0
13
118
1.10
0.07
4.0
3.7
—
—
—
0
0
9
100
0.90
0.06
2.2
1.5
—
—
—
0
0
161
1587
1.02
0.05
3.1
2.7
0.7
0.7
ug/l
0.85
106
932
11
120
0.92
0.05
1.4
1.1
—
—
—
0
0
21
199
1.06
0.04
1.6
1.5
—
—
—
0
0
12
121
0.99
0.00
2.3
2.2
—
—
—
0
0
12
121
0.99
0.00
1.8
2.0
—
—
—
0
0
17
169
1.01
0.00
1.1
1.1
—
—
—
0
0
16
156
1.03
0.00
1.8
1.6
—
—
—
0
0
11
113
0.97
0.00
1.2
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
8.2
—
0
7
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
21.1
—
0
7
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
36.0
—
0
7
0
6
0.00
0.00
0.0
1.0
—
29.3
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
5
52
0.96
0.00
1.0
1.1
—
—
—
0
0
6
60
1.00
0.00
1.7
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
7.8
—
0
6
5
56
0.89
0.00
1.2
1.1
—
—
—
0
0
6
64
0.94
0.00
1.0
1.1
—
—
—
0
0
5
53
0.94
0.00
2.0
3.4
—
—
—
0
0
6
59
1.02
0.00
1.7
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
0.00
1.7
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_HYPETROPHICSCAR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_HYPETROPHICSCAR | 1.08 [0.94, 1.24] | 0.262 |
| Birth year | 0.994 [0.99, 1.0] | 0.164 |
During the follow-up period (1.1.1998 — 31.12.2019), 459 out of 8358 females with L12_HYPETROPHICSCAR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_HYPETROPHICSCAR | 1.039 [0.9, 1.2] | 0.601 |
| Birth year | 0.989 [0.98, 1.0] | 0.031 |
During the follow-up period (1.1.1998 — 31.12.2019), 412 out of 4644 males with L12_HYPETROPHICSCAR died.
Mortality risk
Mortality risk for people of age
years, who have L12_HYPETROPHICSCAR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.099% | 0.281% |
| 5 | 0.609% | 1.569% |
| 10 | 1.573% | 3.594% |
| 15 | 3.011% | 6.578% |
| 20 | 5.302% | 10.837% |
Relationships between endpoints
↥Index endpoint: L12_HYPETROPHICSCAR – Hypertrophic scar
GWS hits: 5
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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