This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Diseases of the skin and subcutaneous tissue
L12_SKIN_SUBCUTAN
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
151630 |
4. Check minimum number of eventsNone |
151630 |
5. Include endpoints |
159899 |
6. Filter based on genotype QC (FinnGen only) |
159899 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 1
- First used in FinnGen datafreeze
- DF10
Diseases of the skin and subcutaneous tissue
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 159899 | 95807 | 64092 |
| Unadjusted period prevalence (%) | 30.89 | 32.66 | 28.25 |
| Median age at first event (years) | 49.18 | 46.41 | 53.32 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 952
- Matched controls
- 5440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L57.0
ICD-10 Finland
Actinic keratosis
312.3
147.2
179
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
21.8
66.2
115
34
L30.9
ICD-10 Finland
Dermatitis, unspecified
25.6
60.9
101
25
E0000UV
ATC
NA
4.0
52.0
269
485
E000001
ATC
NA
4.6
43.7
185
270
D07AC01
ATC
betamethasone; topical
3.2
35.2
238
513
L82
ICD-10 Finland
Seborrhoeic keratosis
22.3
34.6
59
16
L89
ICD-10 Finland
Decubitus ulcer and pressure area
70.4
34.1
47
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
249.6
33.5
42
*
J01DB01
ATC
cefalexin; oral
2.6
33.4
362
1049
D07AC13
ATC
mometasone; topical
3.3
32.9
212
439
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.7
31.2
105
116
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
6.5
30.4
92
88
N02BE01
ATC
paracetamol; systemic, rectal
2.3
29.4
424
1401
TQW99
NOMESCO Finland
Other minor procedure on skin
14.7
28.7
56
23
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
212.3
28.5
36
*
J01DA01
ATC
[U] cefalexin; systemic
2.1
25.0
574
2276
D07AB02
ATC
hydrocortisone butyrate; topical
2.7
24.6
204
491
L30.3
ICD-10 Finland
Infective dermatitis
183.6
24.4
31
*
D07AB08
ATC
desonide; topical
4.6
23.9
97
132
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
65.0
23.8
33
*
A98
ICPC
Health maint/preventive medicine
2.9
23.5
170
374
L40.0
ICD-10 Finland
Psoriasis vulgaris
177.4
23.5
30
*
S18
ICPC
Laceration/cut
4.8
22.8
87
111
7071A
ICD-9 Finland
Chronic ulcer of skin, Ulcer of lower limbs, except decubitus
+∞
21.6
26
*
D07AA02
ATC
hydrocortisone; topical
3.1
20.9
134
271
C03CA01
ATC
furosemide; systemic
2.0
20.4
548
2227
D07XC01
ATC
betamethasone, combinations; topical
3.3
19.9
116
218
N05BB01
ATC
hydroxyzine; systemic
3.7
19.7
100
168
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.4
18.6
198
540
69282
ICD-8 Finland
Other eczema and dermatitis, E microbis
+∞
18.3
22
*
ZXC50
NOMESCO Finland
Cryotherapy
134.4
17.8
23
*
J01FF01
ATC
clindamycin; systemic
2.7
17.1
136
314
L30.0
ICD-10 Finland
Nummular dermatitis
128.4
17.0
22
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
15.2
16.4
31
12
A46
ICD-10 Finland
Erysipelas
2.9
16.4
113
239
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
6.7
16.1
46
41
A28
ICPC
Limited function/disability NOS
3.0
16.0
106
217
L72.1
ICD-10 Finland
Trichilemmal cyst
29.3
16.0
25
5
L29.9
ICD-10 Finland
Pruritus, unspecified
35.1
15.9
24
*
6929X
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[DERMATITITIS ARTEFACTA NUD]
+∞
15.8
19
*
E000006
ATC
NA
5.1
15.7
55
64
D05AX02
ATC
calcipotriol; topical
7.3
15.6
42
34
SPAT1148
SPAT
Treatment of chronic ulcer or burn
4.5
15.6
62
83
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.3
15.5
171
472
I10
ICD-10 Finland
Essential (primary) hypertension
1.9
15.5
346
1273
J01MA02
ATC
ciprofloxacin; systemic
1.9
15.5
313
1112
ZXA05
NOMESCO Finland
Left side
2.3
15.3
173
482
C07AB07
ATC
bisoprolol; oral
1.8
15.3
359
1344
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
28.1
15.2
24
5
69619
ICD-8 Finland
Psoriasis and similar disorders, Psoriasis alia sive NUD (vulgaris)
+∞
14.9
18
*
L30.8
ICD-10 Finland
Other specified dermatitis
+∞
14.9
18
*
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
2.8
14.7
112
251
E000003
ATC
NA
8.1
14.7
37
27
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.7
14.6
118
275
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
11.7
14.4
30
15
D07BA04
ATC
hydrocortisone and antiseptics; topical
3.0
14.1
94
194
L12.0
ICD-10 Finland
Bullous pemphigoid
+∞
14.1
17
*
69299
ICD-8 Finland
Other eczema and dermatitis, Due to other and unspecified cause
+∞
14.1
17
*
H25.1
ICD-10 Finland
Senile nuclear cataract
1.8
13.8
339
1279
R06AE07
ATC
cetirizine; oral
2.2
13.7
161
456
ZXC20
NOMESCO Finland
Use of chemical agents
13.2
13.7
27
12
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
9.6
13.6
31
19
S29
ICPC
Skin symptom/complaint other
6.4
13.4
39
36
6961A
ICD-9 Finland
Psoriasis and similar disorders, Other psoriasis[PSORIASIS VULGARIS]
+∞
13.3
16
*
L28
ICPC
Limited function/disability (L)
3.0
13.2
85
171
R4110
NOMESCO Finland
Physiotherapy
3.0
13.1
87
179
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
12.9
169
501
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.7
12.8
365
1433
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.7
12.7
344
1328
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
+∞
12.4
15
*
C08CA01
ATC
amlodipine; oral
2.0
12.4
198
638
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
2.9
12.3
84
176
M79.6
ICD-10 Finland
Pain in limb
2.8
12.3
86
183
SAA01
NOMESCO Finland
Simple examination of mouth
2.9
12.3
83
173
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
92.8
12.1
16
*
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
16.0
12.0
22
8
J01CA04
ATC
amoxicillin; systemic
1.7
11.9
370
1481
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
11.9
287
1064
D07CC01
ATC
betamethasone and antibiotics; topical
2.6
11.7
92
211
R06AE09
ATC
levocetirizine; oral
5.5
11.7
38
41
SPAT1301
SPAT
No procedures
2.7
11.6
88
196
SPAT1263
SPAT
Sampling
2.5
11.4
98
235
ZZR00
NOMESCO Finland
Flap of skin
7.0
11.4
31
26
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.9
11.4
214
727
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
3.1
11.4
70
136
N02AX02
ATC
tramadol; systemic, rectal
1.8
11.4
276
1024
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
10.8
11.2
24
13
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
46.4
11.2
16
*
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.1
11.2
67
129
H02AB06
ATC
prednisolone; systemic
1.7
11.1
298
1135
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.8
11.0
51
80
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.7
10.9
84
189
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
4.0
10.9
48
72
WX110
NOMESCO Finland
Local anesthesy
2.4
10.9
104
264
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
10.8
197
662
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.2
10.8
63
118
70099
ICD-8 Finland
Corns and callosities
+∞
10.8
13
*
6929B
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA INFECTIOSUM]
+∞
10.8
13
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
10.8
131
374
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.8
10.8
39
48
D09AB01
ATC
zinc bandage without supplements; topical
11.7
10.7
22
11
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
10.6
404
1697
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
10.6
130
374
D02AE01
ATC
carbamide; topical
6.5
10.3
29
26
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
3.2
10.2
60
113
B01AB05
ATC
enoxaparin; parenteral
2.7
10.2
75
165
R23.8
ICD-10 Finland
Other and unspecified skin changes
7.2
10.2
27
22
A02BC02
ATC
pantoprazole; systemic
1.7
10.0
271
1031
SPAT1245
SPAT
Provision of support and information to patient’s family members
4.8
10.0
36
44
G04CA52
ATC
tamsulosin and dutasteride; systemic
3.8
10.0
46
72
D06BB10
ATC
imiquimod; topical
13.8
9.9
19
8
E000007
ATC
NA
8.2
9.9
24
17
R06.0
ICD-10 Finland
Dyspnoea
2.0
9.8
143
442
L29.8
ICD-10 Finland
Other pruritus
29.0
9.7
15
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
9.7
265
1010
SPAT1254
SPAT
Administration of medicine
2.8
9.6
69
150
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.7
9.5
249
936
D07AB01
ATC
clobetasone; topical
4.5
9.5
36
47
SPAT1310
SPAT
Counselling related to known health issue
4.0
9.5
41
61
SPAT1249
SPAT
Treatment-related counselling outside office
2.8
9.5
64
134
P20
ICPC
Memory disturbance
2.9
9.4
61
125
Z00.0
ICD-10 Finland
General medical examination
2.7
9.4
69
151
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.6
9.3
72
163
H13
ICPC
Plugged feeling ear
3.8
9.3
42
65
SPAT1325
SPAT
Vaccination
2.4
9.2
84
209
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.8
9.1
65
140
M54.5
ICD-10 Finland
Low back pain
2.8
9.1
65
140
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.8
9.1
63
134
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
+∞
9.1
11
*
L26
ICD-10 Finland
Exfoliative dermatitis
+∞
9.1
11
*
P01AB01
ATC
metronidazole; oral, rectal
1.9
9.1
166
556
J01CE02
ATC
phenoxymethylpenicillin; oral
1.7
9.0
259
996
J01MA12
ATC
levofloxacin; systemic
1.9
9.0
139
438
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
3.0
9.0
55
108
R06AX27
ATC
desloratadine; oral
4.2
9.0
36
50
E000002
ATC
NA
2.7
8.9
64
139
D07AD01
ATC
clobetasol; topical
3.3
8.9
48
85
QXA50
NOMESCO Finland
Skin cryotherapy, unspecified location
69.3
8.9
12
*
D01AC03
ATC
econazole; topical
2.9
8.9
60
125
SPAT1053
SPAT
Memory test
2.9
8.8
58
120
J02AC01
ATC
fluconazole; systemic
2.1
8.8
116
344
S97
ICPC
Chronic ulcer skin
6.7
8.7
24
21
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.5
8.7
44
75
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
8.7
311
1266
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
4.8
8.7
31
38
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
5.3
8.6
28
31
SPAT1149
SPAT
Suture or treatment of traumatic wound
4.2
8.5
34
47
WX408
NOMESCO Finland
General anesthesy, balanced
3.0
8.4
52
103
SAA03
NOMESCO Finland
Extended examination of mouth
3.7
8.4
39
62
C44.39
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face other or unspecified histology
8.3
8.4
20
14
SAA02
NOMESCO Finland
Basic examination of mouth
2.9
8.3
55
114
L40.9
ICD-10 Finland
Psoriasis, unspecified
+∞
8.3
10
*
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
5.3
8.3
27
30
SPAT1216
SPAT
Assessment of functional ability
2.8
8.3
57
121
G04CA02
ATC
tamsulosin; oral
1.6
8.2
316
1307
QAA99
NOMESCO Finland
Other local destruction of skin of head or neck
25.0
8.2
13
*
D07AC14
ATC
methylprednisolone aceponate; topical
4.3
8.1
32
44
A02BC03
ATC
lansoprazole; oral
1.7
8.1
209
778
ZXA00
NOMESCO Finland
Right side
1.8
8.1
154
522
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.5
8.0
39
65
A02BC05
ATC
esomeprazole; systemic
1.8
8.0
147
492
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.8
7.9
161
558
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
4.6
7.9
29
37
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
2.3
7.9
76
195
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.8
7.8
54
114
D05BB02
ATC
acitretin; oral
12.4
7.7
15
7
R60.0
ICD-10 Finland
Localized oedema
3.0
7.6
46
89
D01BA02
ATC
terbinafine; oral; topical
2.2
7.5
79
212
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
2.6
7.5
59
136
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
7.5
49
100
R03BB04
ATC
tiotropium bromide; inhalant
1.9
7.5
117
370
SPAT1304
SPAT
Counselling and guidance related to ageing
4.2
7.5
30
42
D07BC01
ATC
betamethasone and antiseptics; topical
2.3
7.5
78
207
KMAK
NOMESCO Finland
NA
2.7
7.5
53
115
H81
ICPC
Excessive ear wax
3.0
7.5
45
87
L85.3
ICD-10 Finland
Xerosis cutis
23.1
7.5
12
*
69600
ICD-8 Finland
Psoriasis and similar disorders, Psoriatic arthropathy
+∞
7.5
9
*
L20.0
ICD-10 Finland
Besnier prurigo
+∞
7.5
9
*
68599
ICD-8 Finland
Pilonidal cyst
+∞
7.5
9
*
134
Kela drug reimbursment
General erythroderma
+∞
7.5
9
*
L43.8
ICD-10 Finland
Other lichen planus
+∞
7.5
9
*
L03.9
ICD-10 Finland
Cellulitis, unspecified
31.7
7.3
11
*
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
31.7
7.3
11
*
AA1AD
NOMESCO Finland
CT of head and brain
2.1
7.3
89
254
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.0
7.3
44
86
H26.4
ICD-10 Finland
After-cataract
2.2
7.2
81
224
D01AC02
ATC
miconazole; topical
2.0
7.2
98
294
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
4.4
7.1
27
36
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
3.5
7.0
34
57
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
4.3
7.0
27
37
G47.3
ICD-10 Finland
Sleep apnoea
4.3
7.0
27
37
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
6.5
6.9
19
17
D03BA02
ATC
collagenase; topical
6.5
6.9
19
17
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
17.3
6.9
12
*
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
7.0
6.9
18
15
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.8
6.9
30
46
L17
ICPC
Foot/toe symptom/complaint
3.8
6.9
30
46
N06AX11
ATC
mirtazapine; oral
1.8
6.8
118
387
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.4
6.8
58
141
SPAT1153
SPAT
Removal of sutures
3.2
6.8
37
67
I50.0
ICD-10 Finland
Congestive heart failure
1.7
6.8
164
596
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
21.1
6.7
11
*
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
6.5
6.6
18
16
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
+∞
6.6
8
*
69240
ICD-8 Finland
Other eczema and dermatitis, Due to other chemicals
+∞
6.6
8
*
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
10.1
6.6
14
8
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
28.8
6.6
10
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
6.6
97
299
B01AA03
ATC
warfarin; systemic
1.5
6.6
295
1253
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
51.8
6.5
9
*
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
51.8
6.5
9
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.5
6.4
296
1261
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
10.7
6.3
13
7
SPAT1312
SPAT
General health counselling
3.3
6.3
32
56
J01FA15
ATC
telithromycin; oral
3.8
6.3
27
41
XKD00
NOMESCO Finland
Uroflowmetry
1.8
6.3
117
393
UKC02
NOMESCO Finland
Cystoscopy
1.7
6.3
146
525
N40
ICD-10 Finland
Hyperplasia of prostate
1.5
6.3
255
1059
SFA10
NOMESCO Finland
Fillning on one surface of tooth
3.0
6.2
38
75
WX320
NOMESCO Finland
Spinalanesthesy
2.2
6.2
65
175
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
2.6
6.1
47
108
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
3.0
6.0
37
73
D03BA52
ATC
collagenase, combinations; topical
3.8
6.0
26
40
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
19.2
6.0
10
*
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: L12_SKIN_SUBCUTAN – Diseases of the skin and subcutaneous tissue
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).