Paracetamol of NSAID medication

RX_PARACETAMOL_NSAID

No definition available.

Endpoint definition

FinnGen phenotype data

414262 individuals

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Apply sex-specific rule None

414262

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Check conditions None

414262

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Check pre-conditions, main-only, mode, registry filters

Medicine purchases: ATC N02BE01|N02BE51|M01A|M01B

1 out of 7 registries used, show all original rules.

344241

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Check minimum number of events

Min. number of events 3

344241

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Include endpoints None

344241

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Remove individuals based on genotype QC

314977

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RX_PARACETAMOL_NSAID

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
Number of individuals 314977 183675 131302
Unadjusted prevalence (%) 83.53 87.13 78.97
Mean age at first event (years) 40.90 38.10 44.80

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 0.73 [0.67, 0.79] 9.1e-14 27415
15 years 0.01 0.49 [0.46, 0.53] 2.9e-87 12464
5 years 0.00 0.60 [0.56, 0.64] 1.5e-53 3153
1 year 0.00 0.67 [0.60, 0.76] 1.7e-10 592

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: RX_PARACETAMOL_NSAID – Paracetamol of NSAID medication
GWS hits: 15

Survival analyses between endpoints

Plot

before Paracetamol of NSAID medication
after Paracetamol of NSAID medication

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Drugs most likely to be purchased after Paracetamol of NSAID medication

Endpoint not on priority list, no data to show.