Other benign neoplasms of uterus

CD2_BENIGN_UTERUS_OTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D26
  • Cause of death: ICD-10 D26

2 out of 7 registries used, show all original rules.

414

4. Check minimum number of events

None

414

5. Include endpoints

1936

6. Filter based on genotype QC (FinnGen only)

1936

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Alia neoplasmata benigna uteri

Similar endpoints

List of similar endpoints to Other benign neoplasms of uterus based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 24514 24514 -
Only index persons 19081 19081 -
Unadjusted period prevalence (%)
Whole population 0.70 0.70 -
Only index persons 0.70 0.70 -
Median age at first event (years)
Whole population - 47.18 -
Only index persons - 45.30 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1936 1936 -
Unadjusted period prevalence (%) 0.66 0.66 -
Median age at first event (years) 41.38 41.38 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1758
Matched controls
17580
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
21900
ICD-8 Finland
Other benign neoplasm of uterus, Papiloma, polyp
+∞
323.0
1066
*
D26.1
ICD-10 Finland
Other benign neoplasm: Corpus uteri
1831.7
168.5
161
*
D26.0
ICD-10 Finland
Other benign neoplasm: Cervix uteri
+∞
145.9
138
*
2191A
ICD-9 Finland
Other benign neoplasm of uterus, Corpus uteri
+∞
73.4
70
*
21920
ICD-8 Finland
NA
+∞
72.4
69
*
21901
ICD-8 Finland
NA
+∞
69.2
66
*
D26.9
ICD-10 Finland
Other benign neoplasm: Uterus, unspecified
+∞
57.6
55
*
2190A
ICD-9 Finland
Other benign neoplasm of uterus, Cervix uteri
+∞
49.2
47
*
8113
FHL
Fractional scraping
2.8
47.0
360
1502
21998
ICD-8 Finland
Other benign neoplasm of uterus, Loco alio definito
+∞
37.6
36
*
62660
ICD-8 Finland
Disorders of menstruation, Intermenstrual bleeding
3.2
34.0
190
635
21999
ICD-8 Finland
Other benign neoplasm of uterus, Other and unspecified
+∞
32.4
31
*
21899
ICD-8 Finland
Uterine fibroma
2.5
30.6
271
1203
6227A
ICD-9 Finland
Noninflammatory disorders of cervix, Mucous polyp of cervix
5.0
19.3
62
127
62620
ICD-8 Finland
Disorders of menstruation, Excessive
3.0
18.1
106
365
8111
FHL
Taking a biopsy from the mouth of the uterus at the operating room or under anesthesia (vulvabiopsia 8474, vaginabiopsia 8411)
10.2
17.4
34
34
21910
ICD-8 Finland
Other benign neoplasm of uterus, Benign cyst
+∞
15.6
15
*
62699
ICD-8 Finland
Disorders of menstruation, Other
2.3
14.0
134
612
N84.1
ICD-10 Finland
Polyp of cervix uteri
3.0
13.4
77
263
62650
ICD-8 Finland
Disorders of menstruation, Irregular
3.1
12.7
72
242
62670
ICD-8 Finland
Disorders of menstruation, Postmenopausal bleeding
3.3
12.0
59
182
8339
FHL
Other measure in this category
9.0
11.7
24
27
LDB00
NOMESCO Finland
Excision of lesion of cervix uteri
4.0
11.7
46
118
62800
ICD-8 Finland
Sterility, female, Sterilitas primaria
3.3
9.3
46
144
6266A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Metrorrhagia
2.0
9.3
117
602
LCD00
NOMESCO Finland
Hysterectomy
1.9
9.1
128
689
00000
ICD-8 Finland
NA
3.8
9.0
37
100
62110
ICD-8 Finland
Other diseases of cervix, Erythroplasia of cervix
7.9
8.4
18
23
8305
FHL
Supravaginal amputation or resection
2.4
8.1
65
274
LCB25
NOMESCO Finland
Hysteroscopic excision of lesion
1.9
7.9
109
586
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.7
7.7
174
1092
62000
ICD-8 Finland
Infective diseases of cervix uteri, Cervicitis chronica
3.8
7.6
30
80
62521
ICD-8 Finland
Other diseases of uterus, Hyperplasia glandularis cystica endometrii
3.7
7.4
30
82
D26.7
ICD-10 Finland
Other benign neoplasm: Other parts of uterus
+∞
7.3
7
*
N84.0
ICD-10 Finland
Polyp of corpus uteri
1.6
6.7
168
1087
-
ICD-10 Finland
NA
0.2
6.4
*
261
2198X
ICD-9 Finland
Other benign neoplasm of uterus, Other specified parts of uterus
+∞
6.3
6
*
Y0609
ICD-8 Finland
Examination of the urinary and genital organs, Genital organs
2.4
6.2
47
195

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
747
5458
1.60
20.97
4.8
4.4
—
—
—
0
0
172
975
1.84
11.90
3.5
3.4
5.3
5.2
kpa
0.48
148
885
170
964
1.84
11.75
3.5
3.4
7.4
7.4
ph
0.01
27
126
864
7153
1.38
10.46
4.1
4.1
59.6
110.4
ng/l
0.39
635
5354
302
2056
1.56
10.44
4.6
4.5
—
—
—
0
0
1144
12838
0.73
9.68
22.8
22.3
329.2
329.4
g/l
0.42
1138
12701
704
5749
1.35
8.87
5.9
5.4
—
—
—
0
0
111
608
1.88
8.59
3.8
3.7
25.7
25.1
mmol/l
1.15
99
544
121
699
1.78
7.90
3.6
3.5
—
—
—
0
0
47
190
2.51
7.85
7.2
5.8
7.7
7.4
mmol/l
0.19
40
157
166
1062
1.62
7.44
4.0
3.0
3.8
4.1
e9/l
0.90
106
745
826
7094
1.29
6.71
2.3
2.2
—
—
—
0
0
199
1376
1.50
6.33
3.4
4.0
107.1
72.7
u/ml
0.23
192
1315
201
1411
1.47
5.94
6.5
5.0
—
—
—
0
0
527
4327
1.30
5.89
5.0
4.4
—
—
—
0
0
1004
8928
1.26
5.81
5.1
5.2
1.2
1.2
mmol/l
4.25
874
7922
652
5541
1.27
5.47
2.5
2.4
62.9
58.4
u/l
0.39
597
5010
1329
12305
1.26
5.01
6.4
5.9
1481.1
4388.1
e6/l
2.13
36
167
1320
12217
1.25
4.97
5.8
5.3
—
—
—
0
0
340
2688
1.32
4.93
30.4
28.9
1.4
1.4
inr
0.03
32
345
849
7499
1.24
4.91
6.3
5.7
0.7
0.7
%
0.68
771
6866
1134
10335
1.23
4.86
4.0
4.1
6.8
6.7
mmol/l
0.22
1074
9636
844
7458
1.23
4.84
9.4
9.8
1.2
1.3
inr
0.59
225
1994
32
139
2.32
4.69
2.7
3.3
—
—
—
0
0
1717
16477
1.37
4.62
17.9
15.7
—
—
—
0
0
870
7739
1.23
4.61
6.5
5.9
8.5
8.7
%
0.68
787
7094
511
4303
1.25
4.48
1.8
1.7
117493938.4
18385194.7
pmol/l
1.24
383
3405
863
7697
1.22
4.38
6.2
5.6
2.7
2.7
%
0.55
780
7041
1438
13510
1.25
4.38
5.0
4.6
15.2
15.2
pmol/l
0.31
1257
12000
496
4173
1.25
4.37
3.4
3.2
—
—
—
0
0
152
1075
1.45
4.36
3.2
3.1
4.6
4.4
pmol/l
0.44
135
917
1027
9322
1.22
4.36
5.6
5.5
11.1
11.0
umol/l
0.10
970
8743
69
408
1.72
4.29
2.1
2.1
128.4
124.0
g/l
0.88
49
289
879
7889
1.21
4.09
6.4
5.8
26.2
27.1
%
1.46
789
7197
713
6274
1.22
4.06
3.1
3.1
1568.2
1556.8
ng/l
0.02
602
5386
1365
12805
1.22
3.94
4.8
4.4
14.4
15.0
mm/h
0.85
1212
11615
644
5626
1.22
3.92
2.3
2.3
—
—
—
0
0
864
7775
1.20
3.83
6.0
5.6
58.9
58.0
%
1.14
778
7125
179
1335
1.38
3.82
3.2
3.8
0.1
0.1
%
0.42
47
337
1078
9902
1.20
3.81
5.8
5.9
1.2
1.2
mmol/l
3.90
851
8259
1427
13464
1.23
3.81
7.7
7.2
82.4
79.6
u/l
1.00
1317
12465
64
385
1.68
3.78
3.0
2.9
26.2
25.8
mmol/l
0.23
56
335
119
833
1.46
3.64
2.4
2.1
—
—
—
0
0
1687
16249
1.30
3.60
17.2
16.3
21.5
23.4
mg/l
1.68
1383
13117
167
1250
1.37
3.50
3.4
3.8
0.0
0.6
%
0.88
43
280
183
1396
1.34
3.40
3.3
3.7
0.6
0.8
%
1.07
48
364
1795
17478
1.37
3.25
26.1
24.5
6.8
6.7
e9/l
0.26
1739
16844
495
4282
1.21
3.24
1.9
1.8
1190.9
1195.0
nmol/l
0.03
351
3097
234
1863
1.29
3.22
1.3
1.3
—
—
—
0
0
1753
17023
1.32
3.12
20.4
19.5
139.5
139.5
mmol/l
0.03
1705
16527
30
152
1.99
3.10
1.1
1.1
—
—
—
0
0
17
69
2.48
2.96
1.1
1.2
6.0
5.7
mmol/l
0.89
17
63
1792
17473
1.34
2.95
26.1
24.5
255.4
255.8
e9/l
0.09
1742
16915
1749
16997
1.30
2.94
12.1
11.2
24.0
22.1
u/l
1.53
1654
16205
1792
17474
1.34
2.94
26.0
24.4
91.3
91.5
fl
1.24
1754
17130
1792
17475
1.34
2.93
26.0
24.4
30.1
30.2
pg
1.38
1754
17131
1792
17475
1.34
2.93
26.1
24.5
4.3
4.3
e12/l
0.51
1737
16844
1648
15908
1.24
2.90
5.4
5.1
6.0
6.0
mmol/l
0.08
1449
14058
1792
17478
1.34
2.90
26.3
24.7
129.3
129.2
g/l
0.05
1755
17145
17
72
2.37
2.72
1.1
1.1
5.7
1.7
u/ml
—
5
24
57
365
1.58
2.72
2.4
2.4
16.3
15.6
%
0.69
31
174
1752
17055
1.29
2.71
20.6
19.6
4.0
4.0
mmol/l
0.18
1703
16523
112
822
1.38
2.71
3.0
2.6
0.3
0.3
e6/l
0.28
107
802
54
342
1.60
2.70
2.5
2.7
8.0
8.0
kpa
0.03
48
317
48
296
1.64
2.67
1.7
1.8
1.7
1.6
mmol/l
0.13
48
287
149
1912
0.76
2.64
2.3
3.1
185.2
223.3
ng/l
0.90
138
1739
93
665
1.42
2.62
1.9
1.9
3.2
1.7
ug/l
0.44
67
565
18
81
2.23
2.54
1.1
1.0
0.8
1.8
u/ml
—
6
25
33
186
1.79
2.53
2.5
3.5
—
—
—
0
0
46
287
1.62
2.46
1.4
1.6
—
—
—
0
0
26
138
1.90
2.41
1.2
1.1
5.0
1.6
u/ml
—
7
48
919
8535
1.15
2.34
5.9
5.6
0.2
0.2
e9/l
0.57
781
7285
115
871
1.34
2.32
1.9
1.7
2.0
1.4
g/l
0.84
97
761
216
1778
1.24
2.29
2.8
3.0
84.4
84.3
ng/l
0.01
158
1451
1606
15548
1.19
2.26
6.2
5.7
2.0
2.1
mu/l
0.30
1410
13919
60
411
1.47
2.16
5.1
4.0
23.7
24.4
mg/l
0.04
41
258
887
8251
1.14
2.14
5.8
5.4
0.0
0.0
e9/l
0.41
756
6955
139
1096
1.29
2.13
3.5
4.0
—
—
—
0
0
765
7058
1.14
2.08
3.4
3.3
2.4
2.4
mmol/l
0.55
610
5937
159
1282
1.26
2.04
2.9
3.6
0.4
0.5
%
0.37
32
252
44
286
1.55
2.04
2.8
2.7
—
—
—
0
0
27
155
1.75
2.00
1.3
1.3
—
—
—
0
0
83
1108
0.74
1.99
5.6
5.9
1.3
1.3
%
0.10
83
1102
293
2524
1.19
1.98
1.3
1.2
—
—
—
0
0
880
8214
1.13
1.96
5.8
5.4
0.6
0.6
e9/l
0.25
751
6917
248
2107
1.20
1.95
1.3
1.3
—
—
—
0
0
857
7990
1.13
1.94
4.2
4.0
—
—
—
0
0
407
3609
1.16
1.93
3.0
2.8
490.5
506.0
mosm/kgh2o
0.78
346
3045
6
16
3.76
1.93
1.0
1.1
—
—
—
0
0
51
347
1.48
1.93
2.9
3.5
—
—
—
0
0
10
39
2.57
1.92
1.1
1.5
—
—
—
0
0
83
1100
0.74
1.91
5.6
6.0
0.7
0.7
%
0.15
83
1094
899
8412
1.13
1.91
5.9
5.5
1.9
1.9
e9/l
0.17
779
7212
32
196
1.64
1.90
1.3
1.2
—
—
—
0
0
52
742
0.69
1.88
3.8
4.0
—
—
—
0
0
198
1658
1.22
1.82
1.4
1.3
—
—
—
0
0
94
1215
0.76
1.82
3.4
4.1
—
—
—
0
0
35
223
1.58
1.79
3.0
2.7
—
—
—
0
0
84
1096
0.76
1.75
5.6
6.1
92.1
93.9
%
0.71
84
1091
474
4279
1.14
1.75
2.2
2.2
—
—
—
0
0
65
473
1.39
1.75
2.8
2.4
—
—
—
0
0
1240
12919
0.89
1.73
21.9
20.2
13.9
13.9
%
0.11
1217
12586
30
186
1.62
1.72
4.0
6.2
12.1
13.1
mg/l
0.66
25
167
53
373
1.43
1.72
2.7
4.0
2.9
3.1
mmol/l
0.28
38
270
41
274
1.51
1.72
1.1
1.1
—
—
—
0
0
19
103
1.85
1.71
1.3
1.1
0.2
2.3
u/ml
1.00
12
40
74
554
1.35
1.68
12.8
10.7
—
—
—
0
0
19
104
1.84
1.67
1.9
1.5
—
—
—
0
0
149
1795
0.82
1.62
4.7
5.5
94.3
95.6
%
0.91
143
1724
142
1165
1.24
1.61
2.7
2.6
—
—
—
0
0
130
1588
0.81
1.61
2.7
4.1
—
—
—
0
0
134
1094
1.24
1.60
2.6
2.8
10.5
10.4
g/l
0.17
120
977
144
1185
1.23
1.60
1.3
1.4
—
—
—
0
0
1134
11846
0.90
1.58
4.3
4.3
—
—
—
0
0
6
20
3.01
1.58
1.2
1.1
—
—
—
0
0
805
7546
1.11
1.57
3.8
3.9
—
—
—
0
0
32
207
1.56
1.57
2.4
3.0
—
—
—
0
0
13
64
2.04
1.54
1.2
8.5
101.9
63.1
mg/l
—
7
38
911
8604
1.11
1.54
4.9
4.7
0.0
0.0
estimate
0.00
187
1545
396
3564
1.14
1.53
1.3
1.3
1.1
1.5
u/ml
0.45
80
867
5
15
3.34
1.52
1.0
1.1
—
—
—
0
0
6
140
0.43
1.52
1.3
1.3
—
—
—
0
0
276
3131
0.86
1.51
3.0
2.7
2.2
1.6
e6/l
0.66
159
1711
146
1746
0.82
1.49
2.0
2.4
9.1
5.4
ug/l
0.99
98
1440
24
147
1.64
1.47
1.1
1.1
—
—
—
0
0
185
1575
1.19
1.47
1.8
2.0
423.9
382.3
nmol/l
1.89
167
1406
59
437
1.36
1.47
1.3
1.3
63.5
58.6
mmol/l
0.42
49
349
377
4173
0.88
1.45
3.3
3.0
2.5
2.5
mmol/l
0.37
333
3630
39
269
1.46
1.44
2.9
3.3
0.9
1.3
%
0.85
31
205
64
482
1.34
1.44
2.3
2.4
—
—
—
0
0
34
229
1.49
1.42
1.2
1.2
—
—
nmol/l
—
0
0
216
1872
1.17
1.40
1.8
1.8
126.4
149.5
ug/g
0.54
149
1405
10
46
2.18
1.40
1.3
1.2
—
—
—
0
0
23
142
1.63
1.38
1.0
1.0
1.6
1.5
g/l
0.22
18
122
23
142
1.63
1.38
3.2
2.8
25.3
14.3
mg/l
0.40
18
94
101
815
1.25
1.37
1.2
1.2
121.8
163.1
u/ml
0.65
92
748
141
1676
0.83
1.36
2.8
2.2
47.0
38.8
u/l
0.47
123
1401
157
1330
1.20
1.34
3.6
3.9
—
—
—
0
0
503
4632
1.12
1.33
5.4
5.3
0.0
0.0
estimate
0.80
192
1517
296
2643
1.14
1.30
2.2
2.3
2.4
2.3
g/l
0.51
249
2409
533
4932
1.11
1.29
4.2
3.9
—
—
—
0
0
400
4378
0.89
1.28
4.2
4.6
—
—
—
0
0
27
178
1.52
1.26
2.0
1.7
14635.4
1861.4
u/l
0.74
11
76
72
911
0.78
1.26
6.7
7.0
—
—
—
0
0
318
2862
1.13
1.24
2.3
2.3
11.9
11.7
umol/l
0.16
271
2601
178
2054
0.85
1.24
4.5
5.3
5.1
5.1
kpa
0.11
165
1947
157
1341
1.19
1.23
1.4
1.4
—
—
—
0
0
178
2053
0.85
1.23
4.5
5.3
12.0
12.2
kpa
0.18
166
1941
1516
14787
1.12
1.22
4.4
4.1
1.3
1.3
mmol/l
1.70
1310
12907
533
4947
1.11
1.21
2.4
2.4
3.3
3.2
mg/l
0.43
429
4167
28
188
1.50
1.21
3.4
2.3
3.7
1.8
u/field
0.85
11
59
8
37
2.17
1.21
5.0
2.6
—
—
—
0
0
20
124
1.62
1.21
1.1
1.2
—
—
—
0
0
34
238
1.44
1.20
1.1
1.2
—
—
—
0
0
34
238
1.44
1.20
1.6
1.9
91.1
89.3
%
2.02
34
233
59
453
1.31
1.20
2.7
3.7
7.4
7.4
ph
0.23
52
364
13
71
1.84
1.19
2.8
1.7
—
—
—
0
0
421
3864
1.11
1.18
1.4
1.3
—
—
—
0
0
84
677
1.25
1.18
1.2
1.3
—
—
—
0
0
920
8775
1.09
1.17
4.9
4.7
0.0
0.0
estimate
0.26
200
1543
1556
15210
1.12
1.17
6.7
6.4
40.6
40.4
mmol/mol
0.38
1365
13691
28
190
1.48
1.16
1.2
1.5
0.6
0.7
g/l
0.31
22
147
0
35
0.00
1.15
0.0
1.3
—
—
—
0
0
144
1232
1.18
1.13
1.2
1.2
—
—
—
0
0
79
637
1.25
1.12
3.9
2.9
32.4
50.2
mg/l
0.94
65
538
324
2940
1.12
1.12
1.5
1.4
2.4
2.4
g/l
0.02
174
1550
180
2055
0.86
1.11
4.5
5.3
1.2
1.4
mmol/l
0.33
140
1614
33
234
1.42
1.11
1.1
1.1
—
—
—
0
0
622
5841
1.10
1.11
2.1
2.1
163.5
166.4
u/l
0.06
559
5416
42
560
0.74
1.10
4.8
5.3
1.3
1.2
mmol/l
0.24
36
503
1634
16030
1.12
1.10
5.4
5.3
2.8
2.7
mmol/l
1.57
1420
14257
909
8691
1.09
1.06
6.6
6.3
0.0
0.0
estimate
0.50
194
1512
26
371
0.70
1.04
1.0
1.1
—
—
—
0
0
74
908
0.81
1.03
2.3
2.1
1.1
1.1
%
0.19
74
903
49
377
1.31
1.02
1.2
1.1
154.3
87.1
titre
—
7
17
1586
15554
1.11
1.00
4.9
4.6
4.8
4.7
mmol/l
1.04
1395
13853
78
638
1.23
1.00
4.0
2.9
40.1
133.4
mg/l
0.57
64
544
136
1173
1.17
0.99
1.4
1.3
—
—
—
0
0
1018
9800
1.08
0.98
8.8
8.5
4.2
4.1
e9/l
0.60
874
8454
71
576
1.24
0.98
4.2
5.2
—
—
—
0
0
348
3781
0.90
0.98
4.0
4.0
214.6
209.5
ng/l
0.02
285
3186
0
30
0.00
0.97
0.0
1.6
—
—
—
0
0
0
30
0.00
0.97
0.0
1.6
—
—
—
0
0
525
4922
1.09
0.96
1.7
1.6
20.4
21.8
nmol/l
1.28
402
4089
196
1743
1.14
0.95
1.9
1.9
0.2
0.2
g/l
0.02
181
1615
25
176
1.43
0.90
1.2
1.2
109.6
121.2
u/ml
—
5
40
216
1942
1.13
0.90
2.1
1.7
—
—
—
0
0
312
2866
1.11
0.88
3.0
2.6
0.8
0.8
mmol/l
0.01
282
2596
32
237
1.36
0.88
1.6
1.7
—
—
—
0
0
7
130
0.54
0.87
1.6
1.2
1.2
1.5
nmol/l
—
7
113
30
220
1.37
0.87
1.2
1.2
—
—
—
0
0
242
2196
1.12
0.86
3.8
4.1
1.0
1.0
mmol/l
0.01
206
1965
56
452
1.25
0.84
1.4
1.7
4.5
4.2
iu/l
0.06
15
138
190
1704
1.13
0.83
3.2
3.4
1.2
1.2
mmol/l
0.06
154
1460
47
589
0.79
0.83
1.3
1.2
—
—
—
0
0
41
320
1.29
0.81
3.5
3.4
62.3
58.8
%
1.30
41
320
8
47
1.70
0.80
1.1
1.2
25.9
21.7
%
—
8
42
0
25
0.00
0.79
0.0
1.2
—
160.8
—
0
12
16
106
1.51
0.79
1.3
1.1
—
—
—
0
0
12
187
0.64
0.78
1.2
1.1
—
—
—
0
0
12
74
1.63
0.78
2.3
2.4
—
—
—
0
0
43
340
1.27
0.77
2.0
2.5
1.7
1.6
mg/l
0.19
38
301
269
2473
1.10
0.77
2.4
2.4
19.4
20.1
%
0.41
214
2040
9
53
1.70
0.75
1.3
1.4
—
—
—
0
0
70
588
1.20
0.74
1.5
1.4
277.9
275.5
ug/g
0.03
43
342
74
625
1.19
0.74
2.9
2.7
0.4
0.3
g/l
0.64
24
188
32
245
1.31
0.74
1.3
1.1
—
—
—
0
0
144
1285
1.13
0.71
1.3
1.2
—
—
—
0
0
9
58
1.55
0.69
1.7
1.8
—
—
—
0
0
561
5341
1.07
0.69
3.5
3.3
136.2
49.4
e6/l
0.62
434
3987
11
69
1.60
0.68
1.2
1.2
—
—
—
0
0
582
5552
1.07
0.68
3.8
3.8
8.0
7.8
mg/mmol
0.03
282
3138
137
1226
1.13
0.66
1.6
1.6
—
—
—
0
0
114
1009
1.14
0.65
1.2
1.2
152.6
135.5
iu/ml
0.19
41
377
18
129
1.40
0.63
1.1
1.1
—
—
—
0
0
402
3796
1.07
0.63
1.7
1.8
1.4
1.3
mg/l
0.06
305
2905
11
165
0.66
0.63
1.2
1.2
—
—
—
0
0
5
30
1.67
0.61
1.0
1.1
—
—
—
0
0
296
2766
1.08
0.61
1.3
1.2
13.1
15.1
u/ml
0.18
101
947
160
1759
0.90
0.61
2.7
2.9
5.7
5.8
kpa
0.43
148
1709
236
2186
1.09
0.60
3.2
3.7
4.7
12.6
ug/l
4.41
185
1785
103
913
1.14
0.59
1.2
1.3
75.4
55.0
au/ml
—
5
35
6
35
1.72
0.57
1.0
1.1
—
—
—
0
0
31
247
1.26
0.56
1.3
1.2
26.4
27.3
u/l
0.05
26
209
32
256
1.25
0.56
2.5
2.0
29.4
32.7
umol/l
0.45
25
203
16
115
1.39
0.56
1.1
1.0
0.4
2.2
u/ml
—
5
43
9
61
1.48
0.53
1.9
2.7
—
—
—
0
0
419
4397
0.94
0.53
7.3
6.5
—
—
—
0
0
6
39
1.54
0.53
4.0
1.8
2.4
2.0
mmol/l
—
6
34
24
187
1.29
0.52
1.5
1.7
—
—
—
0
0
342
3236
1.07
0.52
4.2
4.5
—
—
—
0
0
71
620
1.15
0.52
1.7
1.6
—
—
—
0
0
160
1741
0.91
0.52
2.7
2.9
1.9
2.3
mmol/l
0.85
129
1437
6
98
0.61
0.52
1.3
1.7
—
—
—
0
0
730
7069
1.05
0.51
3.0
2.8
101.5
110.4
ug/l
0.99
646
6358
231
2157
1.08
0.51
2.2
2.4
1.7
1.9
%
1.72
187
1867
559
5377
1.06
0.50
2.9
3.0
6.0
5.9
mmol/l
0.14
410
4392
200
1859
1.08
0.49
1.3
1.4
—
—
—
0
0
202
1879
1.08
0.49
2.4
2.2
10.3
8.2
umol/l
0.38
175
1563
11
76
1.45
0.48
1.1
1.1
—
—
—
0
0
26
208
1.25
0.48
1.0
1.0
—
—
—
0
0
7
47
1.49
0.47
1.1
2.0
—
—
—
0
0
21
164
1.28
0.46
2.8
2.8
54.7
57.6
%
0.24
15
99
174
1614
1.09
0.46
3.2
2.4
65.9
66.2
g/l
0.16
139
1413
10
142
0.70
0.46
1.0
1.2
—
—
—
0
0
137
1489
0.91
0.45
2.5
2.6
4.4
4.4
kpa
0.01
127
1440
37
438
0.84
0.44
1.8
1.4
—
—
—
0
0
430
4122
1.06
0.44
2.6
2.5
1133.2
7285.6
umol/l
6.85
330
3419
27
220
1.23
0.43
1.7
1.6
57.8
59.6
%
0.10
19
145
24
193
1.25
0.43
1.0
1.0
—
—
—
0
0
545
5264
1.05
0.42
3.1
3.0
918.6
367.4
mg/l
0.78
252
3013
10
70
1.43
0.41
1.1
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
1.0
—
0
7
11
79
1.39
0.40
2.0
2.0
560.5
488.3
min
—
6
55
0
17
0.00
0.40
0.0
1.1
—
7.4
—
0
17
859
8390
1.04
0.40
4.3
4.0
34.6
34.9
g/l
0.73
778
7658
415
4316
0.95
0.39
3.7
3.6
85.9
89.9
%
2.20
406
4189
1555
15391
1.05
0.39
5.0
4.6
1.6
1.6
mmol/l
0.70
1357
13626
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
154
1436
1.08
0.38
1.5
1.5
—
—
—
0
0
53
599
0.88
0.37
4.0
3.4
—
—
—
0
0
37
429
0.86
0.37
1.7
1.7
—
—
—
0
0
375
3900
0.95
0.36
5.0
5.4
1.0
1.0
kg/l
0.14
60
633
304
2906
1.05
0.36
1.3
1.3
42.2
37.8
iu/ml
0.19
93
930
20
162
1.24
0.35
1.6
1.4
—
—
—
0
0
176
1656
1.07
0.35
2.3
2.3
65.3
70.4
e9/l
1.23
136
1218
14
108
1.30
0.35
23.7
16.7
—
—
—
0
0
14
108
1.30
0.35
1.3
1.2
270.0
147.9
titre
—
6
19
72
651
1.11
0.35
2.7
2.1
36.2
37.3
g/l
0.72
48
533
16
126
1.27
0.35
4.6
1.7
3.5
4.4
mg/l
0.47
16
120
251
2635
0.95
0.35
2.4
1.9
29.9
29.5
s
0.43
243
2532
48
542
0.88
0.34
2.0
1.8
22.0
21.4
s
0.22
39
485
12
91
1.32
0.33
1.7
1.5
74.8
73.3
%
0.15
12
83
24
286
0.84
0.33
1.0
1.2
—
—
—
0
0
739
7223
1.04
0.33
11.0
9.9
0.0
0.0
e9/l
1.20
613
5804
26
219
1.19
0.33
1.6
1.3
285.7
272.1
mosm/kgh2o
1.73
16
155
10
74
1.35
0.32
1.9
1.1
266.3
360.7
u/l
—
10
67
41
361
1.14
0.31
2.6
2.2
—
—
—
0
0
147
1562
0.94
0.31
4.2
4.5
1.3
1.3
mmol/l
0.01
137
1503
474
4883
0.96
0.31
3.4
3.2
—
—
—
0
0
7
96
0.73
0.31
1.7
1.3
—
—
—
0
0
7
96
0.73
0.31
1.7
1.3
—
—
—
0
0
7
98
0.71
0.30
1.9
1.4
—
—
—
0
0
21
250
0.84
0.30
1.3
1.3
—
—
—
0
0
19
228
0.83
0.29
2.9
3.0
—
—
—
0
0
8
107
0.75
0.29
1.0
1.1
—
5.6
—
0
28
53
478
1.11
0.29
1.4
1.3
—
—
—
0
0
8
62
1.29
0.28
1.1
1.0
—
—
—
0
0
15
122
1.23
0.27
1.2
1.1
—
—
—
0
0
22
187
1.18
0.26
1.1
1.0
—
16.3
—
0
10
1385
13980
0.97
0.26
18.9
18.3
37.7
37.5
%
0.20
810
8594
34
384
0.88
0.26
1.0
1.1
—
—
—
0
0
51
462
1.11
0.26
5.3
2.9
—
—
—
0
0
135
1427
0.94
0.26
4.7
5.4
—
—
—
0
0
489
5010
0.97
0.24
3.4
3.2
0.6
0.6
e6/l
0.19
374
3736
37
332
1.12
0.23
1.6
1.6
—
—
—
0
0
17
143
1.19
0.23
1.8
1.3
—
—
—
0
0
17
143
1.19
0.23
1.8
1.3
—
—
—
0
0
17
143
1.19
0.23
1.8
1.3
—
—
—
0
0
17
143
1.19
0.23
1.8
1.3
—
—
—
0
0
5
39
1.28
0.23
1.2
1.1
—
—
—
0
0
5
39
1.28
0.23
1.4
1.9
—
—
—
0
0
5
39
1.28
0.23
1.2
1.1
—
—
—
0
0
5
39
1.28
0.23
1.2
1.1
—
—
—
0
0
451
4402
1.03
0.22
1.6
1.6
1.4
1.3
mmol/l
0.48
342
3677
59
544
1.09
0.22
1.5
1.4
—
—
—
0
0
25
219
1.14
0.22
1.3
1.3
—
—
—
0
0
5
42
1.19
0.21
1.8
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
5
43
1.16
0.21
1.0
1.1
1707.4
1838.3
miu/ml
—
5
43
20
173
1.16
0.21
1.2
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
8.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
0.0
—
0
5
0
13
0.00
0.21
0.0
1.1
—
0.1
—
0
5
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
48
1.25
0.20
1.8
1.3
—
—
—
0
0
21
239
0.88
0.19
1.6
1.2
109.9
234.7
miu/ml
—
9
88
19
165
1.15
0.19
1.2
1.1
278.8
288.4
u/ml
0.07
13
98
10
122
0.82
0.19
1.8
2.5
—
—
—
0
0
23
203
1.13
0.19
2.0
2.8
—
—
—
0
0
68
637
1.07
0.19
1.3
1.2
5.4
0.4
u/ml
—
6
60
43
396
1.09
0.18
1.0
1.1
—
—
—
0
0
19
216
0.88
0.17
1.9
2.3
—
—
—
0
0
31
281
1.10
0.17
1.8
2.2
—
—
—
0
0
16
138
1.16
0.17
1.3
1.2
—
—
—
0
0
8
70
1.14
0.16
1.4
1.2
—
—
—
0
0
16
139
1.15
0.16
1.3
1.2
—
—
—
0
0
16
139
1.15
0.16
1.3
1.2
—
—
—
0
0
291
2842
1.03
0.15
3.2
2.9
5.1
4.7
e6/l
0.26
174
1434
15
130
1.16
0.15
1.3
1.2
—
—
—
0
0
96
917
1.05
0.15
1.3
1.3
—
—
—
0
0
6
80
0.75
0.15
1.3
1.5
—
—
—
0
0
23
207
1.11
0.15
1.6
1.4
—
—
—
0
0
25
227
1.10
0.14
1.2
1.3
52.4
38.1
mu/l
0.20
25
198
24
264
0.91
0.14
1.3
1.5
0.8
0.8
nmol/l
0.20
19
208
8
96
0.83
0.13
1.3
1.7
—
62.4
—
0
7
213
2076
1.03
0.13
1.4
1.3
971.9
567.8
titre
1.39
54
510
11
128
0.86
0.13
2.1
1.4
10.8
10.4
%
0.08
11
128
91
873
1.04
0.13
1.8
1.7
1.6
1.6
g/l
0.24
72
745
11
94
1.17
0.13
1.3
1.2
—
—
—
0
0
10
117
0.85
0.13
1.1
1.1
—
—
—
0
0
9
106
0.85
0.13
2.7
2.9
—
—
—
0
0
9
107
0.84
0.13
3.7
1.6
—
—
—
0
0
153
1486
1.03
0.12
1.8
1.6
—
—
—
0
0
14
123
1.14
0.12
2.1
2.2
—
—
—
0
0
10
116
0.86
0.12
1.1
1.1
—
—
—
0
0
36
337
1.07
0.11
3.0
2.2
33.9
48.2
ug/min
0.30
16
191
47
445
1.06
0.11
2.1
1.5
—
—
—
0
0
387
3813
1.02
0.11
2.7
2.6
7.8
7.6
e6/l
0.06
329
3327
21
192
1.09
0.10
1.1
1.1
—
—
—
0
0
81
840
0.96
0.10
2.5
2.9
23.8
24.5
mmol/l
1.07
72
753
242
2376
1.02
0.10
1.8
1.9
—
—
—
0
0
78
752
1.04
0.10
1.3
1.2
—
—
—
0
0
12
106
1.13
0.09
2.9
5.8
—
—
—
0
0
143
1395
1.03
0.09
3.2
2.2
—
—
—
0
0
66
686
0.96
0.09
1.0
1.1
—
264.7
—
0
15
17
186
0.91
0.09
1.6
1.4
54260.3
87814.6
e6/l
0.22
12
110
11
97
1.13
0.09
1.0
1.1
—
—
—
0
0
26
278
0.93
0.09
1.6
1.3
—
—
—
0
0
12
107
1.12
0.08
1.7
1.4
—
—
—
0
0
12
107
1.12
0.08
2.1
2.2
490.3
623.1
ml
—
6
66
5
64
0.78
0.08
1.6
2.2
—
—
—
0
0
5
64
0.78
0.08
1.0
1.2
—
—
—
0
0
20
185
1.08
0.08
3.1
3.1
5.1
5.2
nmol/l
0.02
20
176
7
64
1.09
0.08
3.1
1.5
0.2
0.2
e9/l
—
7
55
7
65
1.08
0.08
3.0
1.5
451.7
455.1
e6/l
—
7
55
11
98
1.12
0.07
1.0
1.1
—
—
—
0
0
15
137
1.10
0.07
1.2
1.2
—
—
—
0
0
845
8402
1.01
0.07
2.3
2.1
102.0
96.9
pmol/l
1.57
392
3829
7
84
0.83
0.07
1.7
1.9
—
—
—
0
0
13
118
1.10
0.07
1.1
1.4
—
—
—
0
0
9
86
1.05
0.07
1.4
1.1
—
—
—
0
0
83
852
0.97
0.06
1.3
1.2
—
—
—
0
0
70
680
1.03
0.06
1.4
1.4
—
—
—
0
0
32
306
1.05
0.05
1.4
1.5
—
—
—
0
0
19
178
1.07
0.05
1.8
1.1
—
—
—
0
0
18
169
1.07
0.05
1.8
1.4
—
—
—
0
0
48
466
1.03
0.04
1.9
1.6
4170.6
15048.5
e6/l
3.88
31
335
35
363
0.96
0.04
2.1
2.0
—
—
—
0
0
10
91
1.10
0.04
2.3
1.4
—
—
—
0
0
36
372
0.97
0.04
1.1
1.2
—
—
—
0
0
43
441
0.97
0.03
1.4
1.2
2.3
3.5
u/ml
—
7
48
140
1386
1.01
0.03
5.6
5.4
9.7
10.2
mmol/l
0.36
127
1300
11
118
0.93
0.02
1.2
1.1
—
—
—
0
0
609
6070
1.00
0.02
3.6
3.6
7.4
7.4
ph
1.24
134
1084
15
158
0.95
0.02
1.4
1.2
—
—
—
0
0
17
162
1.05
0.02
1.8
1.6
—
—
—
0
0
634
6325
1.00
0.02
4.4
3.9
189.6
133.3
e6/l
0.39
459
4337
68
688
0.99
0.01
2.6
2.9
82.2
1666.4
u/ml
0.98
53
570
10
94
1.06
0.01
1.3
1.4
—
—
—
0
0
10
94
1.06
0.01
2.5
5.1
—
—
—
0
0
11
104
1.06
0.01
1.0
1.1
—
—
—
0
0
18
186
0.97
0.00
1.1
1.2
3.1
4.8
u/ml
—
10
78
18
182
0.99
0.00
2.2
1.7
—
—
—
0
0
10
97
1.03
0.00
1.0
1.4
5.0
5.5
u/l
—
5
81
11
113
0.97
0.00
1.3
1.2
—
—
—
0
0
18
177
1.02
0.00
1.3
1.2
—
—
—
0
0
87
873
1.00
0.00
4.9
6.3
24.9
24.6
mmol/l
0.21
72
801
66
657
1.00
0.00
3.4
3.4
0.9
0.8
nmol/l
0.18
48
507
5
54
0.93
0.00
1.4
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
10.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
282.5
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
152.8
—
0
6
0
5
0.00
0.00
0.0
1.4
—
190.3
—
0
5
10
100
1.00
0.00
2.5
4.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
6.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
5
58
0.86
0.00
1.2
1.2
117.2
144.6
nmol/l
—
5
58
0
8
0.00
0.00
0.0
1.0
—
33.6
—
0
8
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
4.2
—
0
5
9
95
0.95
0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_UTERUS_OTH and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_UTERUS_OTH 1.198 [1.02, 1.4] 0.025
Birth year 0.999 [0.99, 1.01] 0.86

During the follow-up period (1.1.1998 — 31.12.2019), 235 out of 2089 females with CD2_BENIGN_UTERUS_OTH died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_UTERUS_OTH.

N-year risk Females Males
1 0.115% No data
5 0.738% No data
10 1.962% No data
15 3.867% No data
20 6.731% No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_UTERUS_OTH – Other benign neoplasms of uterus

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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