No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
2131 |
4. Check minimum number of eventsNone |
2131 |
5. Include endpointsNone |
2131 |
6. Filter based on genotype QC (FinnGen only) |
2131 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF10
Open bite
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 33503 | 19782 | 13652 |
| Only index persons | 28156 | 16874 | 11282 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.49 | 0.57 | 0.38 |
| Only index persons | 0.54 | 0.62 | 0.43 |
| Median age at first event (years) | |||
| Whole population | 12.86 | 13.55 | 11.78 |
| Only index persons | 14.52 | 15.12 | 13.62 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2131 | 1605 | 526 |
| Unadjusted period prevalence (%) | 0.47 | 0.55 | 0.23 |
| Median age at first event (years) | 29.38 | 30.05 | 27.32 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1824
- Matched controls
- 18241
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
SBB10
NOMESCO Finland
Teeth copy
11.8
323.0
965
1581
K07.24
ICD-10 Finland
Open bite
+∞
323.0
1824
*
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
13.5
322.3
611
654
K07.13
ICD-10 Finland
Retrognaty, mandibular
28.5
306.9
427
193
EB1MA
NOMESCO Finland
Cephalometry with X-ray
12.3
287.4
569
649
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
15.8
268.4
463
383
SJD00
NOMESCO Finland
Removal or reattacment of arrow in fixed orthodontisk device
10.1
243.2
535
721
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
7.0
231.9
679
1422
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
9.1
229.9
538
799
SJD10
NOMESCO Finland
Attachment of arrow to fixed orthodontisk device
9.4
225.7
516
734
K07.60
ICD-10 Finland
Snapping jaw
10.8
225.0
471
571
SAA04
NOMESCO Finland
Special inverstigation of mouth
8.2
211.8
532
873
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
63.2
203.7
237
43
SJC10
NOMESCO Finland
Orthodontic bandage in one tooth
9.8
201.8
445
583
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
14.5
201.2
357
301
SJD20
NOMESCO Finland
Attachment of modifiable arrow of fixed orthodontisk device
10.1
195.5
421
526
SJC50
NOMESCO Finland
Removal of orthodontisk device with at least 7 brackets
8.8
180.0
421
600
EEC05
NOMESCO Finland
Le Fort I osteotomy
112.8
178.1
192
19
SJX10
NOMESCO Finland
Short check-up visit for orthodontisk therapy
6.5
176.9
526
1067
SAA03
NOMESCO Finland
Extended examination of mouth
4.3
176.2
1326
6988
SJB00
NOMESCO Finland
Fitting of loose orthodontic device with user information
7.3
164.0
438
757
SJD40
NOMESCO Finland
Fixation of ready made palatinal or lingual arrow
7.2
158.5
428
748
SJD30
NOMESCO Finland
Demanding attachment of arrow to fixed orthodontisk device
10.2
148.7
313
363
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
9.1
134.9
304
394
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
8.1
134.0
325
475
SXC05
NOMESCO Finland
Other oral or dental procedure
4.9
126.1
477
1227
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.3
123.5
960
4588
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.1
115.8
1120
6142
SJC00
NOMESCO Finland
Bracket with fixed attachment
74.3
110.1
125
18
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
5.3
107.8
368
831
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
21.4
106.1
159
81
K07.14
ICD-10 Finland
Retrognaty, maxillary
28.5
101.9
140
53
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
5.1
94.0
330
760
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
26.3
92.6
130
53
K07.10
ICD-10 Finland
Asymmetry of jaw
46.2
92.0
113
26
SJX20
NOMESCO Finland
Check-up visit for orthodontisk therapy
5.8
92.0
286
571
SJA04
NOMESCO Finland
Very demanding plan for orthodontic care
63.0
92.0
107
18
SJB60
NOMESCO Finland
External device grinding and adaptation
6.3
91.9
264
477
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
5.3
89.1
296
638
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
6.7
87.3
238
400
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
48.8
87.3
106
23
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
3.5
72.1
387
1295
SJC40
NOMESCO Finland
Removal of orthodontisk device with at most 6 brackets
4.5
70.1
273
687
SJA01
NOMESCO Finland
Estimation of need for orthodontic care
35.1
67.0
87
26
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
4.4
66.7
263
668
SJA03
NOMESCO Finland
Demanding plan for orthodontic care
78.3
66.6
75
10
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
64.2
63.9
74
12
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
14.0
63.0
110
83
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
3.8
63.0
298
892
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
67.1
61.8
71
11
K07.11
ICD-10 Finland
Retrognathism (mandibular)(maxillary)
21.0
58.8
88
44
SAA02
NOMESCO Finland
Basic examination of mouth
2.6
55.3
1526
12137
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
7.0
54.5
141
217
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
10.2
48.9
99
102
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
8.9
47.5
104
123
EG1CG
NOMESCO Finland
Extensive MRI examination of mandipular joint with high intensity magnet
27.1
45.7
63
24
F45.8
ICD-10 Finland
Other somatoform disorders
3.2
44.4
264
928
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
4.3
44.0
176
447
SJD50
NOMESCO Finland
Production and attachment of palatinal or lingual arrow
7.3
43.8
109
158
M79.1
ICD-10 Finland
Myalgia
2.8
43.4
322
1306
EBB10
NOMESCO Finland
Insertion of dental implant
11.3
41.3
79
73
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
9.5
41.2
86
94
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
13.2
39.5
70
55
SDA02
NOMESCO Finland
Parodonthologic therapy
2.0
38.6
731
4611
EB1WA
NOMESCO Finland
NA
18.7
37.6
58
32
SJA02
NOMESCO Finland
Plan for orthodontic care
35.2
37.3
48
14
SXC03
NOMESCO Finland
Other oral or dental procedure
12.3
37.3
68
57
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
2.0
37.3
712
4487
SJB10
NOMESCO Finland
Fitting of loose orthodontic device with user information, demanding
5.1
36.9
121
250
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
3.4
36.3
187
588
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
30.8
36.2
48
16
K07.61
ICD-10 Finland
Cracking jaw joint
5.5
35.3
108
206
EEC02
NOMESCO Finland
Rapid expansion of maxilla
183.5
34.9
36
*
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
3.2
34.5
199
678
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
4.0
34.1
145
388
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
16.7
32.5
52
32
SAA01
NOMESCO Finland
Simple examination of mouth
2.0
32.1
1449
12069
SPC20
NOMESCO Finland
Attachment of crone of tooth to implant
14.5
30.2
51
36
K00.00
ICD-10 Finland
Hypodontia
5.5
30.0
91
172
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.2
30.0
119
299
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
6.6
30.0
79
125
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
8.4
29.7
66
81
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
12.1
29.0
53
45
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.8
28.5
616
3958
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.7
27.4
198
778
EBB15
NOMESCO Finland
Insertion of dental implant abutment
13.8
26.8
46
34
SJE90
NOMESCO Finland
Finishing face of orthodontick therapy
9.7
26.5
54
57
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
26.2
26.2
36
14
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
10.1
26.0
52
53
SJX00
NOMESCO Finland
Reparation of orthodontiskt device by dentist
6.5
25.8
68
108
WZA90
NOMESCO Finland
Other doctors statement
1.8
25.7
545
3453
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.9
25.4
495
3046
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
8.3
25.2
56
69
K07.4
ICD-10 Finland
Malocclusion, unspecified
4.8
24.6
83
178
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
3.1
24.5
145
502
P01BA02
ATC
hydroxychloroquine; oral
2.9
23.8
150
539
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
10.0
23.6
47
48
EDC30
NOMESCO Finland
Genioplasty
65.8
22.9
26
*
K07.23
ICD-10 Finland
Deep bite
2.7
22.7
167
661
EBA10
NOMESCO Finland
Surgical removal of tooth
1.9
22.3
366
2105
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
4.5
22.3
80
183
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
4.2
22.3
87
216
K01.0
ICD-10 Finland
Embedded teeth
3.8
22.0
95
258
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.1
21.4
124
424
ZXA10
NOMESCO Finland
Bilateral
2.0
21.4
291
1557
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
7.4
21.3
51
71
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.8
20.9
144
550
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.5
20.7
166
693
K03.64
ICD-10 Finland
Dental calculus supragingival
1.6
20.2
656
4649
OIKK
NOMESCO Finland
NA
2.4
20.2
185
827
A07EC01
ATC
sulfasalazine; oral, rectal
2.7
19.8
137
524
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
1.8
19.8
427
2681
EMAK
NOMESCO Finland
NA
3.2
19.7
107
350
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
5.1
19.4
62
126
TEG10
NOMESCO Finland
Injection of diagnostic or therapeutic substance into mandibular joint
31.7
19.3
25
8
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.9
19.3
80
211
K07.55
ICD-10 Finland
Malocclusion caused by tongue, lip and finger habits
22.8
19.1
27
12
EGC30
NOMESCO Finland
Prosthetic replacement of mandibular joint
55.6
18.9
22
*
TEG00
NOMESCO Finland
Punction of mandibular joint
24.0
18.6
26
11
SPC10
NOMESCO Finland
Attachment of standard crone of tooth
7.2
18.6
45
64
K05.30
ICD-10 Finland
Periodontitis complex
2.4
18.6
164
718
K06.00
ICD-10 Finland
Local gingivore traction
5.5
18.2
54
101
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.9
18.1
76
203
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.8
18.1
392
2457
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
3.8
17.7
76
207
K03.66
ICD-10 Finland
Tooth plaque
2.2
17.5
187
897
EGA05
NOMESCO Finland
Rinsing of mandipular joint
181.7
17.5
18
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
17.5
283
1607
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
12.2
16.8
30
25
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.5
16.7
130
533
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
10.5
16.7
32
31
EFB50
NOMESCO Finland
Orthodontic procedure connected with ortognathic surgery
+∞
16.7
16
*
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
15.2
16.7
27
18
D19
ICPC
Teeth/gum symptom/complaint
1.6
16.5
542
3808
Z01.2
ICD-10 Finland
Dental examination
1.5
16.2
900
7143
K07.68
ICD-10 Finland
Other disorders of the jaw joint
7.1
16.1
39
56
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
16.1
440
2939
K03.00
ICD-10 Finland
Approximal wear
2.7
15.9
113
440
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
26.5
15.6
21
8
ECA70
NOMESCO Finland
Regenerative parodontal operation or gingiva and alveolus transplantation
19.4
15.6
23
12
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
16.2
15.2
24
15
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
25.2
14.7
20
8
G47.3
ICD-10 Finland
Sleep apnoea
1.9
14.5
233
1318
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
36.3
14.4
18
5
SPB10
NOMESCO Finland
Production of temporary crone to tooth
9.2
14.2
29
32
R06.5
ICD-10 Finland
Mouth breathing
2.2
13.8
140
654
K07.6
ICD-10 Finland
Temporomandibular joint disorders
6.1
13.8
37
62
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
13.8
145
692
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
3.5
13.6
62
179
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
2.6
13.6
99
391
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
11.0
13.5
25
23
EB1TW
NOMESCO Finland
3D modelling of dentition
34.3
13.5
17
5
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.5
13.3
606
4548
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.4
12.8
801
6402
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
12.7
316
2043
K05.31
ICD-10 Finland
Periodontitis pronounced
2.4
12.7
104
440
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.0
12.6
72
244
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
3.5
12.5
58
170
L88
ICPC
Rheumatoid/seropositive arthritis
3.2
12.2
64
207
EBW99
NOMESCO Finland
Other operation on tooth
26.9
12.0
16
6
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.4
11.9
1093
9347
EGA00
NOMESCO Finland
Arthroscopy of mandibular joint
14.7
11.8
19
13
G50.1
ICD-10 Finland
Atypical facial pain
4.9
11.7
37
76
K07.03
ICD-10 Finland
Micrognatia (hypoplasia) of the upper jaw
16.5
11.7
18
11
K07.28
ICD-10 Finland
Another anomaly in the relationship between the dental arches
13.7
11.5
19
14
L04AA01
ATC
[U] ciclosporin; systemic
5.4
11.3
33
62
SPB20
NOMESCO Finland
Temporary bridge between two or more teeth
11.9
11.3
20
17
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
11.2
433
3115
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
15.6
10.8
17
11
ECA50
NOMESCO Finland
Parodontal operation
9.6
10.7
21
22
EG1DG
NOMESCO Finland
Very extensive MRI examination of mandipular joint with high intensity magnet
21.6
10.7
15
7
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
10.7
337
2311
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
10.6
295
1955
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.0
10.5
141
745
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.0
10.5
128
652
L04AB04
ATC
adalimumab; parenteral
3.5
10.4
47
136
EG1AD
NOMESCO Finland
CT of mandipular joint
110.6
10.4
11
*
EEC00
NOMESCO Finland
Segmental osteotomy of maxilla
+∞
10.4
10
*
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
3.9
10.2
40
103
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
1.5
10.2
340
2360
N03AX12
ATC
gabapentin; oral
1.8
9.9
172
996
H02AB09
ATC
hydrocortisone; systemic
2.7
9.9
67
256
KAY20
NOMESCO Finland
NA
2.3
9.9
92
417
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.3
9.9
86
377
R4110
NOMESCO Finland
Physiotherapy
1.5
9.7
359
2547
S03.0
ICD-10 Finland
Dislocation of jaw
5.2
9.7
29
57
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.2
9.7
49
156
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
9.7
460
3439
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
9.6
104
502
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
2.7
9.3
60
225
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
8.0
8.8
19
24
L04AB01
ATC
etanercept; parenteral
3.6
8.8
38
107
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.9
8.6
34
89
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.6
8.6
259
1748
SPA20
NOMESCO Finland
Selection and insertion of implantdistans
11.6
8.6
15
13
G47.8
ICD-10 Finland
Other sleep disorders
4.4
8.5
29
66
H02AB06
ATC
prednisolone; systemic
1.4
8.5
594
4745
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.7
8.5
56
213
KMAK
NOMESCO Finland
NA
1.3
8.5
851
7198
RK220
NOMESCO Finland
NA
6.4
8.5
21
33
OIKH
NOMESCO Finland
NA
2.0
8.4
105
542
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.7
8.3
161
967
K02.0
ICD-10 Finland
Caries limited to enamel
1.4
8.3
382
2825
H20.1
ICD-10 Finland
Chronic iridocyclitis
4.8
8.2
26
55
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
8.1
985
8550
M13.9
ICD-10 Finland
Arthritis, unspecified
2.0
8.1
100
513
XF404
NOMESCO Finland
Ambulatory ECG
2.0
8.0
101
523
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
1.8
7.9
135
777
K07.35
ICD-10 Finland
Impacted or embedded teeth with abnormal position of such teeth or adjacent teeth
3.2
7.9
39
123
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
7.9
884
7572
SJB30
NOMESCO Finland
Extraoral device arrangement and user information
2.8
7.9
47
168
WX110
NOMESCO Finland
Local anesthesy
1.3
7.9
1253
11304
SCA03
NOMESCO Finland
Preventive oral health care, extensive
1.8
7.9
126
712
N03AX16
ATC
pregabalin; oral
1.5
7.8
252
1731
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
6.4
7.7
19
30
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.5
7.7
285
2019
SJC20
NOMESCO Finland
Extraoral ofthodontisk pulling device arrangement and urser information
3.2
7.6
37
116
K07.01
ICD-10 Finland
Hyperplasia, hypoplasia mandibular
11.9
7.6
13
11
ECW06
NOMESCO Finland
Insertion of mini-implant or miniscrew
25.1
7.6
10
*
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
3.6
7.6
32
90
J02AC01
ATC
fluconazole; systemic
1.3
7.5
615
5020
KAY40
NOMESCO Finland
NA
1.9
7.5
101
536
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
7.5
553
4440
R01AD12
ATC
fluticasone furoate; nasal
1.4
7.4
541
4329
N03AF01
ATC
carbamazepine; oral, rectal
2.7
7.4
48
181
L04AA17
ATC
[U] adalimumab; parenteral
13.4
7.4
12
9
Z50.1
ICD-10 Finland
Other physical therapy
2.3
7.3
66
295
M25.5
ICD-10 Finland
Pain in joint
1.4
7.3
409
3130
L04AB05
ATC
certolizumab pegol; parenteral
6.9
7.3
17
25
M01CB01
ATC
sodium aurothiomalate; parenteral
4.9
7.3
22
45
EBA00
NOMESCO Finland
Extraction of tooth
1.3
7.3
606
4947
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.6
7.3
192
1256
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
6.3
7.2
18
29
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.3
7.2
66
299
POLI
NOMESCO Finland
NA
20.1
7.1
10
5
R51.81
ICD-10 Finland
Facial pain NOS
3.0
7.1
37
123
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.5
7.0
290
2095
A02BC03
ATC
lansoprazole; oral
1.5
7.0
271
1936
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
3.2
6.9
34
108
P01AB01
ATC
metronidazole; oral, rectal
1.3
6.9
524
4210
SPAT1301
SPAT
No procedures
1.4
6.9
476
3769
J34.2
ICD-10 Finland
Deviated nasal septum
2.2
6.9
66
304
D82
ICPC
Teeth/gum disease
1.3
6.9
665
5537
K06.18
ICD-10 Finland
Another gingival hyperplasia
5.5
6.9
19
35
M01AE02
ATC
naproxen; oral, rectal
1.3
6.9
985
8665
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
6.9
131
781
EB1BA
NOMESCO Finland
Extensive intraoral X-ray examination
13.8
6.9
11
8
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.6
6.9
29
82
SAALT
NOMESCO Finland
NA
2.5
6.9
52
215
SDA05
NOMESCO Finland
Very demanding and lengthy parodonthologic therapy
2.0
6.8
82
418
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.7
6.8
152
951
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
5.0
6.8
20
40
SPA40
NOMESCO Finland
Precision impression for dental prosthesis
11.0
6.8
12
11
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
6.8
298
2181
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.0
6.8
37
127
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
6.8
353
2668
5241A
ICD-9 Finland
Dentofacial anomalies, including malocclusion, Anomalies of relationship of jaw to cranial base
40.2
6.8
8
*
K06.10
ICD-10 Finland
Gingival fibromatosis
16.7
6.7
10
6
A02BC01
ATC
omeprazole; systemic
1.4
6.7
304
2236
OIKAL
NOMESCO Finland
NA
2.3
6.7
60
271
EBA12
NOMESCO Finland
Complicated surgical removal of tooth
1.9
6.7
89
473
-2
ICD-10 Finland
NA
2.0
6.6
74
370
F82
ICD-10 Finland
Specific developmental disorder of motor function
3.0
6.6
34
113
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
4.4
6.5
22
51
SPC25
NOMESCO Finland
Other demanding attachment of crone of tooth
10.1
6.5
12
12
M01AH01
ATC
celecoxib; oral (coxibs)
1.6
6.5
163
1050
R01AD08
ATC
fluticasone; nasal
1.4
6.5
418
3272
EEW99
NOMESCO Finland
Other operation on maxilla
70.1
6.4
7
*
EG1CM
NOMESCO Finland
Mandipular joint extensive MRI examination with 3 Tesla magnet
14.4
6.4
10
7
XX7LW
NOMESCO Finland
NA
14.4
6.4
10
7
ND1AA
NOMESCO Finland
Wrist X-ray examination
1.9
6.3
88
475
B03XA01
ATC
erythropoietin; parenteral
5.5
6.3
17
31
RD210
NOMESCO Finland
NA
2.2
6.3
62
292
L04AX01
ATC
azathioprine; systemic
2.0
6.3
78
405
YEA05
NOMESCO Finland
Excision of gingival or connective tissue for transplantation
18.1
6.3
9
5
K03.29
ICD-10 Finland
Erosion of teeth occupational
3.4
6.2
28
84
EEC99
NOMESCO Finland
Other reconstructive operations on maxilla
26.8
6.2
8
*
-1
NOMESCO Finland
NA
1.3
6.2
729
6214
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.8
6.2
93
516
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
4.1
6.2
22
54
SPC30
NOMESCO Finland
Tooth bridge attacment with resins
6.3
6.2
15
24
L04AA13
ATC
leflunomide; oral
2.8
6.1
36
129
S02.62
ICD-10 Finland
Fracture of the condyle of the lower jaw
7.7
6.1
13
17
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
6.1
536
4388
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
6.1
241
1728
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
6.1
234
1666
KAC00
NOMESCO Finland
Nephrectomy
6.7
6.0
14
21
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.5
6.0
239
1713
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.3
6.0
52
230
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
902
6719
1.59
23.35
3.2
2.5
76.3
71.6
nmol/l
5.64
847
6298
283
1758
1.70
14.25
1.6
1.6
1230.5
1179.0
nmol/l
0.33
216
1380
1366
11922
1.41
12.29
5.2
3.8
8.2
8.8
mm/h
1.57
1297
11134
1292
11232
1.38
11.49
7.2
6.3
77.9
79.6
u/l
0.62
1223
10588
354
2446
1.54
11.38
1.5
1.6
13968721.3
32035661.0
pmol/l
0.52
315
2157
1022
8592
1.36
11.02
8.6
6.3
54.5
54.9
%
0.57
986
8148
532
4013
1.43
10.98
2.4
2.4
2.7
2.7
mg/l
0.19
464
3495
1561
14103
1.40
10.35
4.8
3.9
14.5
14.4
pmol/l
2.16
1449
13047
402
2914
1.47
10.16
1.3
1.3
20.1
25.4
iu/ml
0.61
127
867
992
8378
1.34
10.03
3.8
3.1
0.0
0.0
estimate
0.80
212
1683
998
8469
1.34
9.63
3.8
3.1
0.0
0.0
estimate
0.80
217
1703
988
8402
1.33
9.27
5.1
4.3
0.0
0.0
estimate
0.41
220
1752
790
6514
1.34
9.13
3.8
3.1
—
—
—
0
0
1087
9391
1.32
9.03
3.3
3.0
81.2
68.5
ug/l
0.30
1042
8886
1137
9895
1.32
8.92
11.2
8.7
3.6
3.9
e9/l
3.14
1045
8640
170
1051
1.67
8.66
1.7
1.6
7.5
8.4
u/l
0.61
134
818
376
2768
1.44
8.65
1.3
1.3
9.1
9.6
u/ml
0.05
151
1133
1731
16074
1.41
8.56
5.5
4.5
1.8
2.0
mu/l
0.96
1646
15199
791
6573
1.32
8.50
9.2
6.8
1.2
1.2
mmol/l
0.21
682
5647
70
338
2.11
7.75
4.7
7.6
1.6
1.7
%
0.25
65
310
249
1759
1.47
7.07
2.5
2.1
353.1
375.2
nmol/l
1.06
234
1628
219
1513
1.50
6.94
1.3
1.3
142.0
262.1
u/ml
3.05
206
1406
436
3417
1.35
6.76
2.6
2.1
160.1
212.7
u/l
1.18
410
3254
544
4408
1.31
6.69
2.5
2.5
57.7
55.7
u/l
0.30
503
4087
159
1046
1.56
6.32
2.7
2.0
10.5
10.4
nmol/l
0.04
134
915
297
2227
1.39
6.05
2.9
2.4
14.6
14.6
umol/l
0.07
283
2068
346
2660
1.36
6.04
1.5
1.4
21.0
20.1
nmol/l
0.59
298
2369
654
5495
1.27
5.98
5.6
5.1
37.3
37.2
g/l
0.23
612
5138
95
558
1.74
5.91
2.1
2.2
—
—
—
0
0
544
4472
1.29
5.90
4.2
3.3
0.0
0.0
estimate
1.49
214
1714
29
107
2.73
5.86
47.7
32.0
125.3
128.6
ug/l
0.08
24
97
18
50
3.62
5.76
3.6
5.5
—
—
—
0
0
213
1520
1.45
5.74
1.6
1.5
17.2
19.5
iu/l
0.55
171
1224
268
2002
1.39
5.58
2.9
2.4
2.5
2.5
g/l
0.16
252
1852
696
5934
1.26
5.54
9.6
6.5
1.2
1.2
mmol/l
0.14
639
5487
145
965
1.54
5.51
7.5
5.1
66.9
67.1
ng/l
0.02
139
899
582
4867
1.27
5.44
1.9
1.7
99.1
98.0
pmol/l
0.25
308
2668
19
57
3.35
5.44
11.3
7.9
—
—
—
0
0
181
1267
1.47
5.40
2.9
3.3
4.6
4.7
pmol/l
0.13
163
1135
14
34
4.14
5.36
7.9
8.0
—
—
—
0
0
1861
17787
1.37
5.34
12.1
10.2
67.2
67.5
umol/l
0.34
1861
17779
15
39
3.87
5.26
5.9
6.4
—
—
—
0
0
15
39
3.87
5.26
5.9
6.7
—
—
—
0
0
806
7038
1.23
5.07
5.2
5.5
10.0
10.7
umol/l
0.99
754
6572
16
48
3.35
4.60
5.9
3.1
—
—
—
0
0
1219
11169
1.21
4.58
4.6
3.8
505.9
749.3
e6/l
0.18
14
111
959
8589
1.21
4.54
5.5
4.4
6.2
6.2
mmol/l
0.18
865
7785
270
2086
1.34
4.54
3.9
3.2
440.6
627.2
ng/l
1.68
217
1669
639
5501
1.23
4.48
1.5
1.4
2.5
1.7
u/ml
0.76
180
1405
449
3729
1.26
4.34
3.8
3.2
1.0
1.0
kg/l
0.24
59
541
239
1826
1.35
4.33
3.1
2.5
23.7
23.7
%
0.02
208
1606
524
4432
1.24
4.31
2.8
2.9
2.4
2.4
mmol/l
0.22
458
4019
48
255
1.90
4.22
1.2
1.2
—
—
—
0
0
99
647
1.56
4.15
4.9
3.3
141.8
120.3
ng/l
0.16
91
569
1724
16438
1.26
4.09
11.9
10.1
3.9
3.9
mmol/l
0.75
1667
15888
182
1346
1.39
4.05
6.4
4.2
1.4
1.6
%
4.71
169
1231
483
4077
1.24
4.02
2.4
2.6
32.0
31.6
ng/l
0.02
225
1829
366
2994
1.27
4.00
3.2
2.8
157.0
106.8
ug/g
1.06
298
2362
83
529
1.59
3.89
8.6
8.1
24.7
24.2
mmol/l
0.51
78
493
1548
14622
1.21
3.85
3.5
3.2
5.5
5.6
mmol/l
2.21
1440
13644
1830
17612
1.28
3.75
12.0
10.0
18.0
19.9
mg/l
2.00
1397
13119
51
288
1.79
3.74
3.6
3.3
14.8
27.1
mu/l
2.42
51
272
72
450
1.62
3.67
1.4
1.2
3.6
10.4
u/ml
—
10
79
195
1487
1.34
3.60
9.3
6.5
1.7
1.5
mmol/l
0.53
160
1205
867
7827
1.18
3.47
4.3
4.0
—
—
—
0
0
28
132
2.14
3.46
1.5
1.6
25.7
53.5
%
3.60
20
90
46
259
1.79
3.44
1.5
1.4
5.0
5.8
umol/l
0.74
40
242
1378
12937
1.18
3.41
4.4
4.0
36.7
37.4
mmol/mol
2.08
1310
12255
1713
16405
1.23
3.41
12.0
10.0
139.6
139.5
mmol/l
0.38
1665
15902
62
383
1.64
3.34
10.6
7.1
590.0
331.5
iu/ml
—
7
51
70
446
1.59
3.33
1.4
1.2
11.1
3.0
u/ml
—
10
49
245
1956
1.29
3.27
1.7
1.8
—
—
—
0
0
182
1397
1.33
3.24
5.2
4.6
—
—
—
0
0
126
916
1.40
3.16
1.6
1.7
—
—
—
0
0
46
267
1.74
3.13
1.6
1.4
—
—
—
0
0
369
3106
1.23
3.11
3.3
2.6
6.0
8.1
e6/l
2.15
326
2720
226
1798
1.29
3.10
1.2
1.2
87.5
154.6
iu/ml
3.00
96
677
417
3556
1.21
3.09
1.7
1.6
1.3
1.3
mmol/l
1.27
374
3135
23
105
2.20
3.09
2.3
3.0
9.6
10.4
mg/l
0.29
17
91
21
93
2.27
3.03
3.1
5.2
205.1
159.9
umol/l
0.20
15
57
1852
17939
1.25
2.98
10.4
8.2
25.2
25.4
u/l
0.18
1797
17387
52
322
1.63
2.82
1.5
1.3
—
—
—
0
0
25
123
2.04
2.81
5.4
4.0
1.6
1.6
ug/l
0.08
25
118
74
498
1.50
2.81
2.4
1.6
83.0
100.1
u/ml
0.77
13
75
62
402
1.56
2.79
1.1
1.2
28.9
31.1
u/ml
—
7
34
1646
15794
1.19
2.75
15.5
12.4
13.3
13.3
%
0.14
1620
15491
52
325
1.62
2.73
1.2
1.4
—
—
—
0
0
87
609
1.45
2.73
3.8
2.6
0.1
0.1
e6/l
0.01
82
589
237
1929
1.26
2.72
12.0
7.3
1.1
1.1
mmol/l
0.02
224
1831
58
373
1.57
2.71
1.8
1.8
—
—
—
0
0
612
5460
1.17
2.69
3.3
3.3
29.1
29.5
u/l
0.15
583
5203
176
1386
1.29
2.64
3.6
2.9
10.1
10.2
g/l
0.03
162
1291
1503
14334
1.16
2.64
3.4
3.0
1.1
1.2
mmol/l
2.91
1432
13580
83
585
1.44
2.53
1.6
1.8
0.2
0.2
g/l
1.54
76
553
209
1693
1.26
2.51
4.1
3.7
5.6
6.5
umol/l
0.49
169
1407
168
1327
1.29
2.48
1.8
1.7
—
—
—
0
0
413
3592
1.19
2.46
2.2
2.1
0.8
0.9
mg/l
1.06
302
2592
33
189
1.76
2.41
4.5
3.2
1.4
1.1
%
0.20
24
150
42
258
1.64
2.39
1.8
1.9
—
—
—
0
0
64
434
1.49
2.39
1.5
1.4
17.6
17.0
u/l
0.06
55
377
53
346
1.55
2.36
3.4
3.9
3.0
3.9
e9/l
3.52
53
346
127
974
1.32
2.34
1.4
1.4
—
—
—
0
0
84
604
1.41
2.32
1.6
1.8
1.1
1.2
g/l
1.07
76
571
86
621
1.40
2.32
1.6
1.6
0.1
0.2
iu/ml
0.50
19
119
1568
15064
1.15
2.26
3.8
3.3
4.6
4.7
mmol/l
2.68
1501
14326
1577
15159
1.16
2.25
3.9
3.5
2.8
2.8
mmol/l
3.23
1499
14303
1558
14976
1.15
2.17
3.8
3.3
1.5
1.5
mmol/l
0.38
1484
14188
240
2008
1.22
2.17
3.5
3.0
29.1
29.6
s
0.84
230
1953
56
378
1.49
2.16
1.9
1.8
—
—
—
0
0
53
354
1.51
2.15
3.6
4.2
48.7
55.2
%
3.31
53
354
13
55
2.37
2.12
1.0
1.4
—
—
—
0
0
154
1233
1.27
2.08
3.5
4.5
248.0
239.2
u/l
0.20
145
1184
162
1305
1.26
2.08
3.5
3.2
0.2
0.2
g/l
0.14
151
1236
89
664
1.36
2.01
2.5
2.8
5.9
6.2
umol/l
0.14
58
511
21
111
1.90
2.01
2.7
3.0
58.7
57.1
%
0.11
12
74
88
656
1.36
2.00
2.1
1.5
—
—
—
0
0
37
232
1.61
1.99
1.8
1.8
—
—
—
0
0
2040
20112
1.34
1.98
18.8
14.8
263.4
264.3
e9/l
0.24
2004
19577
9
33
2.73
1.93
1.0
1.1
—
—
—
0
0
66
472
1.41
1.93
2.1
1.6
45.4
41.0
nmol/l
0.34
66
462
175
1437
1.24
1.92
4.1
3.1
32.2
32.3
%
0.04
125
1075
160
1301
1.25
1.92
1.7
1.7
—
—
—
0
0
54
375
1.45
1.85
1.4
1.4
307.7
326.3
ug/g
0.27
24
196
16
79
2.03
1.85
2.8
3.2
27.3
25.9
ug/l
0.06
16
79
87
657
1.34
1.84
4.4
4.4
3.2
3.3
g/l
0.09
80
628
5
12
4.17
1.82
1.0
1.5
72.2
95.7
ng/l
—
5
12
39
254
1.55
1.82
1.9
1.6
7681.2
10515.4
e6/l
0.37
32
192
14
66
2.13
1.82
2.9
2.3
14.9
17.0
umol/l
0.35
14
66
111
1404
0.78
1.81
2.2
2.3
37.5
73.3
u/l
0.51
96
1178
31
191
1.63
1.81
3.0
3.2
0.2
0.2
e9/l
0.45
26
160
31
191
1.63
1.81
2.9
3.1
9.4
10.2
%
0.26
21
139
94
721
1.32
1.79
1.6
2.4
67.3
67.3
g/l
0.01
89
678
31
193
1.62
1.75
3.0
3.2
422.5
510.8
e6/l
0.93
26
159
694
6408
1.12
1.75
1.8
1.8
—
—
—
0
0
173
1435
1.22
1.74
1.7
1.6
333.7
313.8
mu/l
0.26
157
1284
12
54
2.23
1.74
1.0
1.4
—
—
—
0
0
2041
20148
1.31
1.73
18.8
14.8
6.5
6.7
e9/l
3.44
2006
19575
120
1491
0.79
1.70
2.2
1.9
—
—
—
0
0
2040
20140
1.30
1.70
18.8
14.7
4.5
4.6
e12/l
0.49
2005
19577
2041
20152
1.30
1.70
18.9
14.8
134.9
135.1
g/l
0.18
2026
19906
23
134
1.72
1.66
1.3
1.2
1.0
1.0
ratio
—
7
60
1514
14623
1.12
1.65
8.5
8.0
96.6
96.5
ml/min/173m2
0.05
1228
11408
438
3955
1.14
1.58
3.4
3.5
7.9
8.3
mmol/l
1.02
391
3505
7
26
2.70
1.58
1.0
1.0
—
—
—
0
0
83
639
1.31
1.58
2.2
1.5
173.8
213.7
u/ml
0.84
43
351
18
99
1.83
1.57
1.4
1.1
90.0
92.4
%
—
8
51
86
670
1.30
1.51
1.8
2.0
5.0
6.6
ug/l
0.59
79
595
128
1047
1.24
1.50
10.5
8.4
13.6
13.7
kpa
0.05
123
1003
128
1048
1.24
1.49
10.6
8.4
5.0
5.1
kpa
0.25
123
1003
24
148
1.63
1.44
13.8
14.3
816.8
805.1
nmol/l
0.04
24
142
104
836
1.26
1.44
1.6
1.7
—
—
—
0
0
17
95
1.80
1.43
1.5
1.1
88.1
89.4
%
—
7
48
418
3793
1.13
1.40
2.3
2.2
—
—
—
0
0
83
652
1.28
1.39
3.8
4.1
158.1
162.8
%
0.24
75
635
36
247
1.47
1.38
1.1
1.2
0.8
7.0
u/ml
1.88
13
100
16
89
1.80
1.37
5.1
1.9
1.1
3.2
u/field
2.04
11
53
6
23
2.61
1.36
1.0
1.0
—
—
—
0
0
19
112
1.70
1.35
2.1
1.8
—
—
—
0
0
240
2103
1.16
1.35
2.8
3.0
176.7
624.3
ng/l
3.27
122
1135
83
655
1.28
1.35
1.1
1.1
2.8
6.7
u/ml
1.11
15
96
29
192
1.52
1.32
1.7
1.9
—
—
—
0
0
31
209
1.49
1.30
3.5
3.9
75.2
142.9
u/ml
—
7
64
29
193
1.51
1.29
2.1
1.4
—
—
—
0
0
38
268
1.43
1.28
2.4
2.8
—
—
—
0
0
16
92
1.74
1.25
2.0
2.5
105.7
106.0
mmol/l
0.14
16
92
118
981
1.21
1.23
4.0
3.6
1.2
1.2
mmol/l
0.03
109
842
9
45
2.00
1.23
1.0
1.4
—
—
—
0
0
9
45
2.00
1.23
1.0
1.4
—
—
—
0
0
89
719
1.25
1.21
6.0
4.4
96.1
93.5
%
0.63
82
671
16
93
1.73
1.21
2.0
2.5
3.8
3.9
mmol/l
0.62
16
93
27
180
1.51
1.21
3.2
3.2
—
—
—
0
0
27
181
1.50
1.18
2.8
2.9
683.6
850.0
e6/l
—
9
49
8
38
2.11
1.18
1.6
1.9
—
—
—
0
0
132
1115
1.20
1.18
1.2
1.2
58.7
37.3
au/ml
—
5
45
24
157
1.53
1.17
1.1
1.1
—
—
—
0
0
24
157
1.53
1.17
1.1
1.1
—
—
—
0
0
24
157
1.53
1.17
1.1
1.1
—
—
—
0
0
24
157
1.53
1.17
1.1
1.1
—
—
—
0
0
24
158
1.52
1.14
1.1
1.1
—
—
—
0
0
27
183
1.48
1.13
1.3
1.4
—
—
—
0
0
298
2687
1.13
1.13
1.7
1.7
1.4
1.4
%
0.23
267
2444
35
250
1.41
1.13
1.3
1.3
—
—
—
0
0
336
3052
1.12
1.12
3.1
2.5
2334.4
3405.4
umol/l
0.31
300
2749
55
423
1.31
1.12
1.7
2.2
1.2
1.3
g/l
0.32
48
380
7
30
2.34
1.12
5.4
9.9
—
—
—
0
0
36
259
1.40
1.11
6.3
3.7
3.8
3.8
mmol/l
0.11
36
241
221
1956
1.14
1.11
2.0
2.4
2.4
2.4
mmol/l
0.28
199
1701
27
184
1.47
1.11
1.3
1.4
—
—
—
0
0
1663
16263
1.10
1.11
3.9
3.9
—
—
—
0
0
552
5150
1.10
1.10
2.3
2.2
—
—
—
0
0
7
32
2.19
1.08
5.1
3.9
—
—
—
0
0
16
97
1.65
1.06
1.1
1.1
95.6
87.2
%
0.55
16
80
27
186
1.46
1.06
1.3
1.4
—
—
—
0
0
17
105
1.62
1.06
1.1
1.6
—
—
—
0
0
17
105
1.62
1.06
1.1
1.6
—
—
—
0
0
17
105
1.62
1.06
1.1
1.6
—
—
—
0
0
5
22
2.28
1.03
1.6
1.1
—
—
—
0
0
139
1197
1.17
1.02
17.0
9.4
6.4
6.5
mmol/l
0.10
133
1164
122
1040
1.18
1.01
11.0
8.5
1.0
0.8
mmol/l
0.22
92
795
23
155
1.49
1.01
1.5
1.7
—
—
—
0
0
7
35
2.00
1.00
2.0
1.6
—
—
—
0
0
48
370
1.30
0.99
1.3
1.6
—
—
—
0
0
26
182
1.43
0.96
1.3
1.4
—
—
—
0
0
27
191
1.42
0.94
1.5
1.6
—
—
—
0
0
140
1216
1.16
0.94
13.8
5.6
5.0
5.1
kpa
0.71
131
1156
231
2077
1.13
0.94
9.2
5.1
0.8
0.8
mmol/l
0.79
219
1966
26
183
1.43
0.93
1.3
1.4
—
—
—
0
0
9
52
1.73
0.92
1.8
2.8
—
—
—
0
0
9
52
1.73
0.92
3.0
1.4
8.3
8.3
ug/l
—
9
52
26
184
1.42
0.91
1.3
1.4
—
—
—
0
0
1214
11764
1.07
0.91
3.3
3.0
33.5
33.9
u/l
0.08
1159
11263
8
43
1.86
0.87
7.1
3.0
1.2
1.2
mmol/l
—
8
38
232
2104
1.12
0.83
2.3
2.3
5482.7
7151.1
u/l
0.38
85
812
132
1155
1.15
0.83
1.3
1.3
247.5
235.1
miu/ml
0.16
68
584
136
1193
1.15
0.83
14.1
5.6
1.1
1.1
mmol/l
0.15
99
847
465
4367
1.08
0.81
1.6
1.5
—
—
—
0
0
130
1140
1.15
0.80
3.7
3.4
22.6
21.8
%
0.19
48
414
8
48
1.67
0.78
1.0
2.1
—
—
—
0
0
8
48
1.67
0.78
1.0
2.1
—
—
—
0
0
33
251
1.32
0.78
1.5
1.5
—
—
—
0
0
22
157
1.41
0.76
1.3
1.4
0.6
1.4
promille
1.90
15
127
6
34
1.77
0.76
1.5
2.7
—
—
—
0
0
16
108
1.49
0.73
1.1
1.2
—
—
—
0
0
592
5633
1.07
0.73
2.4
2.4
—
—
—
0
0
9
56
1.61
0.72
1.0
1.2
—
—
—
0
0
61
508
1.21
0.71
1.1
1.1
6.7
7.9
u/ml
0.20
32
239
95
824
1.16
0.70
1.2
1.2
0.7
2.9
u/ml
3.26
37
415
161
1448
1.12
0.70
4.1
3.6
1.8
1.9
ug/l
0.16
149
1321
40
319
1.26
0.69
2.7
2.0
3.0
2.1
ug/l
0.28
35
288
31
239
1.30
0.69
5.2
2.1
—
—
—
0
0
136
1215
1.13
0.66
2.3
2.3
28.0
22.2
au/ml
—
6
98
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
10
62
1.62
0.65
1.5
1.1
—
63.7
—
0
14
438
4145
1.07
0.63
3.8
3.1
0.3
0.3
e6/l
0.05
355
3058
62
525
1.19
0.63
1.6
1.9
—
—
—
0
0
19
138
1.38
0.62
1.7
2.0
0.5
0.1
nmol/l
0.54
12
107
10
63
1.59
0.61
1.5
1.1
—
84.6
—
0
14
50
416
1.21
0.61
1.1
1.1
—
—
—
0
0
8
50
1.60
0.61
1.1
2.0
—
—
—
0
0
126
1402
0.89
0.60
1.4
1.4
—
—
—
0
0
14
97
1.45
0.59
2.1
1.1
—
—
—
0
0
127
1405
0.90
0.55
1.4
1.4
—
—
—
0
0
127
1404
0.90
0.55
1.4
1.4
—
—
—
0
0
9
61
1.48
0.53
1.0
1.9
—
—
—
0
0
9
61
1.48
0.53
1.1
1.9
—
—
—
0
0
9
61
1.48
0.53
1.0
1.9
—
—
—
0
0
9
61
1.48
0.53
1.0
1.9
—
—
—
0
0
67
770
0.87
0.53
2.7
4.1
21.7
23.8
ug/l
0.04
44
564
23
294
0.78
0.53
2.0
3.4
98.2
888.8
u/ml
0.84
18
250
127
1399
0.90
0.52
1.4
1.4
—
—
—
0
0
149
1364
1.10
0.51
1.4
1.2
519.1
125.0
titre
0.40
11
33
13
92
1.42
0.50
1.2
1.8
—
686592.2
—
0
9
6
41
1.46
0.50
1.0
1.1
—
—
—
0
0
10
67
1.49
0.49
1.8
1.5
—
—
—
0
0
34
411
0.82
0.49
1.5
1.6
7.5
7.3
mmol/l
0.31
23
243
7
45
1.56
0.49
3.4
2.8
31.3
31.5
umol/l
—
7
35
40
335
1.20
0.49
1.1
1.2
—
—
—
0
0
85
757
1.13
0.48
1.3
1.3
—
—
—
0
0
13
93
1.40
0.48
5.5
3.3
25.3
61.5
u/ml
0.96
13
93
25
199
1.26
0.48
1.5
1.5
—
—
—
0
0
33
272
1.22
0.47
1.1
1.5
3.0
3.1
g/l
0.31
26
226
38
318
1.20
0.47
2.0
2.5
132.7
134.4
g/l
0.22
32
258
187
2010
0.92
0.47
1.5
1.5
—
—
—
0
0
23
288
0.80
0.46
1.6
1.8
—
—
—
0
0
58
664
0.87
0.46
1.3
1.3
—
—
—
0
0
16
120
1.34
0.46
1.1
1.2
—
2.7
u/ml
—
0
10
7
49
1.43
0.46
1.0
1.1
—
—
—
0
0
34
283
1.20
0.45
1.1
1.5
3.8
3.8
g/l
0.03
26
219
34
283
1.20
0.45
1.1
1.5
7.5
7.4
g/l
0.10
26
235
34
283
1.20
0.45
1.1
1.5
—
—
—
0
0
25
202
1.24
0.43
1.3
2.0
—
—
—
0
0
93
840
1.11
0.43
3.2
2.4
0.7
0.7
ug/l
0.06
50
447
15
113
1.33
0.42
1.0
1.0
—
—
—
0
0
79
880
0.89
0.42
1.6
1.5
—
—
—
0
0
6
92
0.65
0.42
1.2
1.8
—
—
—
0
0
22
176
1.25
0.41
1.3
1.5
—
—
—
0
0
64
567
1.13
0.41
1.5
1.5
0.6
0.4
nmol/l
0.27
52
469
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
8
60
1.33
0.40
1.3
1.1
17.6
14.7
u/l
—
8
51
1774
17581
1.05
0.39
13.8
10.9
39.8
40.0
%
0.84
1416
14663
7
104
0.67
0.39
1.0
1.2
—
—
—
0
0
294
2799
1.06
0.39
3.7
4.2
11.5
17.0
mg/mmol
0.29
187
1879
23
187
1.23
0.39
2.0
1.3
—
0.6
nmol/l
—
0
5
306
2921
1.06
0.37
2.0
1.9
—
—
—
0
0
131
1215
1.08
0.37
2.5
2.5
—
—
—
0
0
84
763
1.11
0.37
1.3
1.5
—
—
—
0
0
36
309
1.17
0.36
3.1
3.2
18.1
25.1
mg/l
1.10
22
188
12
157
0.76
0.35
1.3
1.5
7.8
10.1
umol/l
1.79
12
148
6
42
1.43
0.35
1.3
1.5
—
—
—
0
0
16
126
1.27
0.35
2.7
4.5
—
120.5
—
0
18
52
585
0.89
0.35
1.3
1.9
—
—
—
0
0
29
341
0.85
0.35
2.4
2.5
0.8
0.7
nmol/l
0.01
23
293
143
1529
0.93
0.34
1.4
1.5
—
—
—
0
0
108
998
1.09
0.34
1.8
2.0
—
—
—
0
0
26
218
1.20
0.34
1.0
1.0
—
—
—
0
0
57
510
1.12
0.33
1.8
2.0
173.7
4.6
iu/l
0.48
19
204
57
635
0.89
0.33
1.7
1.5
—
—
—
0
0
14
177
0.79
0.33
1.0
1.3
—
30.2
—
0
6
26
219
1.19
0.33
1.0
1.1
—
—
—
0
0
11
83
1.33
0.32
2.9
2.2
155.5
154.2
nmol/l
0.01
11
75
62
560
1.11
0.32
1.2
1.1
—
—
—
0
0
12
92
1.31
0.31
2.0
2.3
—
—
—
0
0
20
165
1.21
0.31
1.1
1.2
—
—
—
0
0
190
1802
1.06
0.31
1.4
1.4
—
—
—
0
0
20
166
1.21
0.29
1.1
1.2
—
—
—
0
0
160
1512
1.06
0.29
1.3
1.4
—
—
—
0
0
81
746
1.09
0.29
1.2
1.2
—
—
—
0
0
19
158
1.20
0.28
1.1
1.8
—
—
—
0
0
33
289
1.14
0.28
4.2
3.3
33.9
33.0
umol/l
0.10
28
261
222
2320
0.95
0.28
3.5
2.8
4.2
3.7
e6/l
0.25
137
1193
22
186
1.18
0.28
1.0
1.1
—
—
—
0
0
61
556
1.10
0.27
1.1
1.1
4.6
5.3
u/ml
0.13
34
243
8
63
1.27
0.27
1.3
1.1
711.4
72.1
u/l
—
8
54
62
567
1.10
0.26
1.2
1.1
—
—
—
0
0
13
104
1.25
0.26
1.3
1.6
—
—
—
0
0
22
188
1.17
0.25
2.0
1.7
—
—
—
0
0
15
123
1.22
0.25
1.9
1.8
35.3
20.0
mg/l
—
6
39
6
81
0.74
0.24
1.0
1.1
7.8
2.9
u/ml
—
6
66
21
180
1.17
0.23
1.1
1.3
—
—
—
0
0
28
247
1.14
0.22
1.3
1.5
—
—
—
0
0
11
88
1.25
0.22
1.3
1.2
—
—
—
0
0
7
92
0.76
0.22
2.1
1.7
—
—
—
0
0
5
40
1.25
0.22
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
20
173
1.16
0.21
1.1
1.2
—
—
—
0
0
11
89
1.24
0.21
1.2
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
2.8
—
—
—
0
0
22
251
0.88
0.21
2.3
2.6
16.6
17.5
%
0.99
14
140
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
51
471
1.08
0.19
1.6
1.8
—
—
—
0
0
31
343
0.90
0.19
1.5
1.5
5.9
6.7
mmol/l
1.20
20
231
36
328
1.10
0.18
1.1
1.1
—
—
—
0
0
25
224
1.12
0.17
1.1
1.1
2.0
7.6
iu/ml
—
9
54
57
608
0.94
0.16
1.4
1.6
—
—
—
0
0
27
244
1.11
0.16
1.1
1.2
—
—
—
0
0
16
183
0.87
0.16
1.7
1.5
—
—
—
0
0
11
130
0.85
0.16
1.4
1.6
—
—
—
0
0
13
151
0.86
0.15
1.0
1.1
—
—
—
0
0
9
78
1.15
0.15
12.0
2.9
—
—
—
0
0
9
78
1.15
0.15
12.0
2.9
—
—
—
0
0
15
131
1.15
0.14
1.2
1.4
4.0
5.5
ug/l
1.83
15
108
8
97
0.82
0.13
1.0
1.4
—
74.1
—
0
10
131
1266
1.04
0.13
1.9
1.8
—
—
—
0
0
247
2414
1.03
0.13
3.3
2.6
0.8
1.2
e6/l
1.07
161
1289
18
161
1.12
0.13
1.3
1.4
0.2
0.5
u/ml
—
10
48
11
127
0.87
0.12
1.0
1.1
2347.0
1410.3
miu/ml
1.17
11
127
36
385
0.93
0.12
1.6
1.5
—
—
—
0
0
18
162
1.11
0.11
1.6
1.5
—
—
—
0
0
18
162
1.11
0.11
2.8
2.1
—
—
—
0
0
366
3601
1.02
0.11
2.2
2.1
—
—
—
0
0
22
201
1.10
0.11
1.4
1.6
—
—
—
0
0
33
308
1.07
0.11
1.2
1.3
2.2
4.9
u/ml
1.43
14
111
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
25
270
0.93
0.10
15.9
6.7
0.3
0.4
u/ml
1.08
20
150
5
45
1.11
0.09
1.0
1.1
—
—
—
0
0
5
48
1.04
0.09
1.8
2.2
—
—
—
0
0
6
54
1.11
0.09
1.2
1.0
3.0
3.2
kpa
—
6
43
6
55
1.09
0.09
1.2
1.0
7.0
7.3
kpa
—
6
44
66
684
0.96
0.08
1.1
1.2
—
—
—
0
0
7
65
1.08
0.08
1.1
1.1
15.6
48.7
u/ml
—
7
65
275
2788
0.98
0.07
1.5
1.5
—
—
—
0
0
8
77
1.04
0.07
1.1
1.2
—
—
—
0
0
8
78
1.03
0.07
1.0
1.0
—
—
—
0
0
8
78
1.03
0.07
1.0
1.2
—
—
—
0
0
7
85
0.82
0.07
1.3
1.2
108.9
109.8
%
—
7
73
9
86
1.05
0.07
4.6
3.9
—
—
—
0
0
8
92
0.87
0.06
1.4
1.3
—
—
—
0
0
8
93
0.86
0.06
1.1
1.1
79.4
87.1
%
—
8
93
8
93
0.86
0.06
1.1
1.1
—
—
—
0
0
154
1567
0.98
0.06
1.1
1.1
—
—
—
0
0
9
102
0.88
0.06
1.0
1.1
—
—
—
0
0
33
316
1.05
0.05
1.4
1.3
—
—
—
0
0
33
316
1.05
0.05
1.4
1.3
—
—
—
0
0
10
90
1.11
0.05
1.7
1.2
—
—
—
0
0
13
120
1.08
0.05
1.0
1.1
—
—
—
0
0
13
120
1.08
0.05
1.2
1.2
—
—
—
0
0
46
447
1.03
0.04
1.1
1.1
—
—
—
0
0
93
914
1.02
0.04
1.8
1.6
3.3
4.5
mg/l
0.72
62
613
71
724
0.98
0.03
1.1
1.1
1.0
3.2
u/ml
3.01
23
206
30
311
0.96
0.03
1.3
1.2
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
10
108
0.93
0.03
1.0
1.1
—
—
—
0
0
136
1347
1.01
0.02
1.6
1.6
—
—
—
0
0
114
1128
1.01
0.02
1.4
1.5
—
—
—
0
0
25
242
1.03
0.02
1.1
1.1
—
—
—
0
0
98
990
0.99
0.02
11.4
12.8
1.0
1.2
inr
2.61
25
167
100
1010
0.99
0.02
2.3
2.4
83.0
79.2
ml/min/173m2
0.32
36
373
31
302
1.03
0.02
2.0
1.6
—
1960.0
—
0
8
45
443
1.02
0.01
1.7
2.3
27.0
16.8
e6/l
0.17
36
343
15
156
0.96
0.00
1.0
1.1
—
—
—
0
0
38
386
0.98
0.00
1.1
1.1
2.5
2.8
u/ml
0.10
23
173
45
444
1.01
0.00
1.7
2.4
345.8
9198.6
e6/l
0.55
37
360
48
474
1.01
0.00
1.0
1.1
2.9
0.4
u/ml
—
9
136
14
135
1.04
0.00
1.0
1.1
1.0
1.0
u/l
—
5
61
17
169
1.01
0.00
1.3
1.3
—
—
—
0
0
81
811
1.00
0.00
1.4
1.3
—
—
—
0
0
11
106
1.04
0.00
1.0
1.1
—
—
—
0
0
31
308
1.01
0.00
1.3
1.3
2.2
4.5
u/ml
1.93
12
139
5
58
0.86
0.00
1.0
1.1
—
—
—
0
0
5
58
0.86
0.00
1.0
1.1
—
—
—
0
0
5
58
0.86
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
9
90
1.00
0.00
1.2
1.7
—
—
—
0
0
9
93
0.97
0.00
3.8
3.0
1383.2
710.8
u/ml
—
9
93
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
9
90
1.00
0.00
1.1
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
5.9
—
—
—
0
0
6
61
0.98
0.00
1.0
1.2
—
17.2
—
0
14
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
5.6
—
0.3
—
0
5
5
51
0.98
0.00
2.2
1.6
—
—
—
0
0
12
120
1.00
0.00
1.4
1.5
1.0
1.0
g/l
0.06
12
120
0
8
0.00
-0.00
0.0
1.1
—
29.4
—
0
8
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_OPEN_BITE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_OPEN_BITE | 1.305 [1.01, 1.68] | 0.04 |
| Birth year | 0.992 [0.98, 1.0] | 0.077 |
During the follow-up period (1.1.1998 — 31.12.2019), 94 out of 16248 females with K11_OPEN_BITE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_OPEN_BITE | 1.104 [0.83, 1.47] | 0.499 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 83 out of 11181 males with K11_OPEN_BITE died.
Mortality risk
Mortality risk for people of age
years, who have K11_OPEN_BITE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.081% | 0.199% |
| 5 | 0.619% | 1.139% |
| 10 | 1.679% | 2.966% |
| 15 | 3.275% | 5.819% |
| 20 | 5.607% | 9.616% |
Relationships between endpoints
↥Index endpoint: K11_OPEN_BITE – Open bite
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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