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This is a non-core endpoint: only basic statistics are computed.

Carcinoma in situ of skin of eyelid, including canthus

CD2_INSITU_SKIN_EYELID

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D04.1&
  • Hospital discharge: ICD-9 2321
  • Cause of death: ICD-10 D04.1&
  • Cause of death: ICD-9 2321

2 out of 7 registries used, show all original rules.

77

4. Check minimum number of events

None

77

5. Include endpoints

None

77

6. Filter based on genotype QC (FinnGen only)

74

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D04
Name in latin
Carcinoma in situ cutis palpebrae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 74 33 41
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 77.58 77.03 78.03

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
77
Matched controls
770
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D04.1
ICD-10 Finland
Carcinoma in situ: Skin of eyelid, including canthus
+∞
107.9
76
*
L57.0
ICD-10 Finland
Actinic keratosis
9.6
22.8
43
90
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
28.9
20.0
27
14
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
9.0
17.8
28
46
TQW99
NOMESCO Finland
Other minor procedure on skin
12.9
13.2
24
26
CBA10
NOMESCO Finland
Biopsy of eyelid
36.6
12.2
15
5
CBB50
NOMESCO Finland
Excision of lesion of eyelid and reconstruction using graft or flap
140.1
11.8
12
*
C44.11
ICD-10 Finland
Basocellular carcinoma of the skin of the eyelids including the corner of the eye
26.1
11.2
15
7
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.3
10.3
27
71
CBB30
NOMESCO Finland
Excision of lesion of eyelid
18.2
10.0
15
10
R23.8
ICD-10 Finland
Other and unspecified skin changes
4.6
9.4
31
98
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
11.3
8.2
15
16
ZXC15
NOMESCO Finland
Use of photodynamic technique
15.5
7.7
12
9
S21
ICPC
Skin texture symptom/complaint
4.5
7.6
23
67
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
4.6
7.5
22
62
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
5.2
7.2
17
40
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
10.2
6.9
13
15
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
10.7
6.6
12
13
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
4.9
6.5
16
39
D04.8
ICD-10 Finland
Carcinoma in situ: Skin of other sites
+∞
6.3
6
*
C44.12
ICD-10 Finland
Spinocellular carcinoma of the skin of the eyelids including the corner of the eye
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
55
227
5.98
12.61
4.3
2.3
—
—
—
0
0
26
75
4.72
8.75
1.8
1.3
—
—
—
0
0
49
271
3.22
5.77
11.4
6.2
—
—
—
0
0
52
304
3.19
5.44
10.5
5.5
2.07
1.68
e9/l
0.32
46
276
51
298
3.11
5.29
10.7
5.3
0.61
0.61
e9/l
0.06
45
264
51
299
3.09
5.24
10.7
5.4
0.04
0.04
e9/l
0.36
45
264
51
307
2.96
4.85
10.9
5.6
0.21
0.19
e9/l
0.21
44
275
17
54
3.76
4.83
4.5
8.0
—
—
—
0
0
39
212
2.70
4.39
5.5
3.9
—
—
—
0
0
11
24
5.16
3.92
1.0
1.3
—
—
—
0
0
45
277
2.50
3.75
2.6
2.1
89.01
89.52
pmol/l
0.03
27
132
69
554
3.36
3.40
30.2
18.2
33.69
24.26
mg/l
0.96
59
467
61
445
2.78
3.39
5.0
4.5
19.60
14.89
mm/h
0.87
55
403
58
416
2.60
3.28
6.3
5.7
—
337.00
—
0
16
31
170
2.38
3.23
2.5
2.1
3.06
3.21
mg/l
0.11
26
149
34
198
2.28
3.05
3.4
2.3
—
—
—
0
0
15
59
2.92
3.00
1.1
1.2
—
—
—
0
0
70
578
3.32
2.97
33.3
21.5
98.66
86.84
umol/l
0.67
70
578
11
34
3.60
2.86
1.8
2.3
1.22
1.46
g/l
0.61
11
27
46
311
2.19
2.80
8.4
5.5
1.21
1.21
mmol/l
0.11
40
278
29
164
2.23
2.74
3.4
3.1
397.74
4265.78
umol/l
0.78
23
132
12
42
3.19
2.70
3.3
7.2
93.48
92.83
%
0.16
12
42
70
587
3.11
2.63
33.8
21.0
3.99
4.02
mmol/l
0.38
70
566
70
585
3.16
2.62
32.8
21.1
139.06
139.58
mmol/l
0.80
70
565
41
270
2.11
2.61
13.5
11.4
0.00
0.00
e9/l
0.07
33
229
6
12
5.32
2.45
1.2
1.1
—
—
—
0
0
63
502
2.40
2.32
4.7
4.5
1.20
1.22
mmol/l
0.13
57
434
11
41
2.96
2.32
3.1
4.7
25.16
25.03
mmol/l
0.03
11
41
21
111
2.23
2.29
4.2
3.1
1.50
2.23
e6/l
0.27
14
70
65
527
2.50
2.27
6.4
7.4
40.29
41.81
mmol/mol
0.58
59
483
13
55
2.64
2.26
5.4
4.1
—
—
—
0
0
65
530
2.45
2.19
5.1
5.0
3.99
4.30
mmol/l
1.91
59
467
60
474
2.20
2.18
11.3
7.2
81.93
77.55
u/l
0.58
55
443
9
31
3.15
2.15
2.0
1.4
0.58
1.18
g/l
—
9
26
14
64
2.45
2.09
3.0
6.7
115.36
122.44
g/l
0.59
14
64
66
549
2.42
1.99
6.0
5.7
2.20
2.44
mmol/l
1.64
60
478
31
200
1.92
1.97
3.3
3.8
4.75
11.02
mg/mmol
1.06
24
125
29
185
1.91
1.89
3.2
2.8
26.38
76.42
mg/l
1.25
23
115
18
97
2.12
1.86
3.4
4.9
103.06
104.19
mmol/l
0.37
18
97
13
61
2.36
1.84
2.5
2.1
308.62
213.66
ng/l
0.30
13
52
17
90
2.14
1.83
1.8
1.6
—
—
—
0
0
23
137
1.97
1.82
3.6
4.1
—
—
—
0
0
34
231
1.84
1.82
3.1
3.5
2.37
2.34
mmol/l
0.42
29
196
30
196
1.87
1.81
5.9
3.3
0.14
0.43
e6/l
1.60
25
150
54
425
1.91
1.79
7.1
5.0
—
—
—
0
0
35
241
1.83
1.78
3.7
3.8
—
—
—
0
0
23
139
1.93
1.74
4.4
3.8
606.67
183.63
ng/l
0.34
18
121
63
526
2.09
1.70
5.1
5.0
1.35
1.43
mmol/l
0.63
57
459
28
183
1.83
1.67
6.1
3.2
—
—
—
0
0
14
71
2.19
1.66
1.4
1.4
—
—
—
0
0
61
505
2.00
1.66
4.5
4.9
1.94
2.05
mu/l
0.32
55
434
45
341
1.77
1.62
9.6
6.1
1.21
1.21
mmol/l
0.02
40
282
50
393
1.78
1.56
3.1
4.0
15.25
15.29
pmol/l
0.04
45
340
35
251
1.72
1.50
6.6
4.1
140.69
82.30
e6/l
0.27
27
190
26
171
1.79
1.50
7.9
6.8
—
—
—
0
0
17
98
1.94
1.46
11.2
5.5
1.11
1.04
mmol/l
0.35
17
83
30
208
1.72
1.44
4.7
5.0
—
—
—
0
0
7
29
2.55
1.43
3.6
3.0
—
—
—
0
0
8
34
2.51
1.34
1.4
2.6
0.63
0.65
%
—
8
34
8
35
2.43
1.31
2.6
2.5
—
—
—
0
0
31
231
1.57
1.08
5.7
3.5
13.63
307.37
e6/l
0.55
24
181
12
68
1.91
1.08
2.8
1.6
—
—
—
0
0
7
34
2.16
1.06
1.4
2.6
1.33
1.11
%
—
7
34
5
22
2.36
1.05
1.4
1.2
—
—
—
0
0
7
35
2.10
1.03
6.3
3.0
—
—
—
0
0
50
431
1.46
0.79
37.6
23.9
329.56
330.69
g/l
0.39
50
426
14
93
1.62
0.76
5.5
3.0
1.88
1.73
%
0.19
14
81
28
218
1.45
0.75
8.1
4.3
7.37
7.41
ph
—
5
48
40
333
1.42
0.75
24.5
16.6
1.19
1.29
inr
—
9
102
63
572
1.56
0.73
27.6
16.9
—
—
—
0
0
27
211
1.43
0.71
2.4
2.3
59.00
60.76
u/l
0.09
22
195
15
105
1.53
0.66
4.0
2.7
2.27
2.25
g/l
0.05
15
92
15
105
1.53
0.66
4.2
2.7
18.72
22.17
%
0.68
15
89
8
49
1.70
0.64
3.4
4.2
—
—
—
0
0
17
127
1.43
0.56
1.1
1.3
—
—
—
0
0
9
62
1.51
0.55
1.1
1.3
—
—
—
0
0
6
40
1.54
0.53
3.3
5.9
—
—
—
0
0
59
543
1.37
0.49
5.9
5.5
6.08
6.15
mmol/l
0.15
53
475
8
55
1.51
0.45
3.9
2.5
—
—
—
0
0
5
32
1.60
0.43
1.4
1.2
—
—
—
0
0
5
36
1.42
0.39
1.4
3.3
25.68
24.43
mmol/l
—
5
36
6
44
1.39
0.35
2.8
2.6
—
—
—
0
0
7
51
1.41
0.32
1.4
1.7
—
—
—
0
0
11
84
1.36
0.32
1.1
1.2
—
—
—
0
0
32
287
1.20
0.27
6.0
4.7
33.36
40.14
ng/l
0.36
25
234
14
167
0.80
0.25
3.8
4.1
—
—
—
0
0
5
40
1.27
0.23
1.2
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.0
—
—
—
0
0
6
48
1.27
0.21
1.5
1.3
—
—
—
0
0
16
181
0.85
0.16
4.8
4.6
—
—
—
0
0
13
114
1.17
0.13
2.5
1.9
29.63
30.04
s
0.12
13
106
5
43
1.17
0.10
2.4
1.4
—
—
—
0
0
5
44
1.15
0.10
4.0
1.6
—
—
—
0
0
5
45
1.12
0.10
3.0
2.2
13.74
12.90
nmol/l
—
5
38
43
414
1.09
0.09
5.6
4.5
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
4.37
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
15.90
—
0
5
0
5
0.00
-0.00
0.0
4.8
—
57.20
—
0
5
0
8
0.00
-0.00
0.0
4.5
—
5.15
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.0
—
33.17
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
55
0.90
-0.00
2.6
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
6.00
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_SKIN_EYELID – Carcinoma in situ of skin of eyelid, including canthus

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).