brain neoplasm: A neoplasm (disease) that involves the brain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
324 |
4. Check minimum number of eventsNone |
324 |
5. Include endpointsNone |
324 |
6. Filter based on genotype QC (FinnGen only) |
324 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D10
- Name in latin
- Neoplasma benignum oropharyngis
Similar endpoints
↥List of similar endpoints to Benign neoplasm: Other parts of oropharynx based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Other parts of oropharynx
- Benign neoplasm of mouth and pharynx
- Benign neoplasm of mouth and pharynx
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 2025 | 1071 | 939 |
Only index persons | 1865 | 1002 | 863 |
Unadjusted period prevalence (%) | |||
Whole population | 0.03 | 0.03 | 0.03 |
Only index persons | 0.04 | 0.04 | 0.03 |
Median age at first event (years) | |||
Whole population | 51.53 | 52.28 | 50.52 |
Only index persons | 50.66 | 51.48 | 49.72 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 324 | 193 | 131 |
Unadjusted period prevalence (%) | 0.06 | 0.07 | 0.06 |
Median age at first event (years) | 52.67 | 51.17 | 54.89 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 290
- Matched controls
- 2901
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_OROPHA_OTHER and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
CD2_BENIGN_OROPHA_OTHER | 1.256 [0.99, 1.6] | 0.063 |
Birth year | 0.996 [0.99, 1.01] | 0.452 |
During the follow-up period (1.1.1998 — 31.12.2019), 117 out of 834 females with CD2_BENIGN_OROPHA_OTHER died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
CD2_BENIGN_OROPHA_OTHER | 1.677 [1.28, 2.2] | < 0.001 |
Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 137 out of 733 males with CD2_BENIGN_OROPHA_OTHER died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_OROPHA_OTHER.N-year risk | Females | Males |
---|---|---|
1 | 0.14% | 0.328% |
5 | 0.857% | 1.893% |
10 | 2.044% | 4.924% |
15 | 3.593% | 9.149% |
20 | 6.503% | 14.734% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_OROPHA_OTHER – Benign neoplasm: Other parts of oropharynx
GWS hits: -