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Alzheimer’s disease (Late onset), excluding more controls

Endpoint Browser PheWeb

AD_LO_EXMORE

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
G6_AD_WIDE, F5_DEMENTIA, F5_DEMENTIA_U, F5_PSYCH, NEURODIS, MEMLOSS, TRAUMBRAIN_NONCONCUS

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 155025 100212 53777
Only index persons 132407 86940 45467
Unadjusted period prevalence (%)
Whole population 2.38 2.87 1.50
Only index persons 2.69 3.20 1.74
Median age at first event (years)
Whole population 82.51 83.17 81.33
Only index persons 82.80 83.44 81.58

-FinnGen-

Key figures

All Female Male
Number of individuals 9974 4828 5146
Unadjusted period prevalence (%) 1.97 1.65 2.27
Median age at first event (years) 80.66 80.70 80.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2762
Matched controls
24158
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
323.0
706
*
N06DX01
ATC
memantine; oral
1678.8
323.0
1653
21
N05AX08
ATC
risperidone; systemic
136.1
323.0
646
54
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
+∞
323.0
450
*
N06DA04
ATC
galantamine; oral
471.2
323.0
334
7
P20
ICPC
Memory disturbance
20.4
323.0
1491
1313
G30.1
ICD-10 Finland
Alzheimer disease with late onset
1415.4
323.0
2206
70
N06DA03
ATC
rivastigmine; oral, transdermal
1546.2
323.0
857
7
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
541.3
323.0
951
23
AA1AD
NOMESCO Finland
CT of head and brain
7.3
323.0
940
1585
N06DA02
ATC
donepezil; oral
1055.0
323.0
1565
29
F03
ICD-10 Finland
Unspecified dementia
85.3
323.0
450
55
SPAT1053
SPAT
Memory test
6.6
323.0
1317
2942
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
923.0
323.0
585
7
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
29.1
323.0
996
458
N05AH04
ATC
quetiapine; oral
16.2
323.0
568
379
A28
ICPC
Limited function/disability NOS
6.6
299.2
924
1711
P70
ICPC
Dementia
167.4
295.8
322
19
R41.3
ICD-10 Finland
Other amnesia
61.2
277.9
339
55
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
158.7
253.9
278
17
F06.7
ICD-10 Finland
Mild cognitive disorder
48.7
249.7
317
64
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
185.3
231.6
251
13
G30
ICD-10 Finland
Alzheimer disease
535.4
219.2
226
*
TAB00
NOMESCO Finland
Lumbar puncture
29.1
205.7
293
98
G47.3
ICD-10 Finland
Sleep apnoea
18.6
196.7
322
170
G30.8
ICD-10 Finland
Other Alzheimer disease
182.2
195.1
212
11
R53
ICD-10 Finland
Malaise and fatigue
4.7
187.7
761
1797
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
8.1
185.7
460
578
S06.0
ICD-10 Finland
Concussion
24.0
179.0
269
108
SPAT1245
SPAT
Provision of support and information to patient’s family members
12.0
174.0
343
282
N06AX11
ATC
mirtazapine; oral
3.8
170.8
928
2842
SPAT1216
SPAT
Assessment of functional ability
4.2
169.9
777
2039
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
+∞
168.1
168
*
N03AG01
ATC
valproic acid; systemic, rectal
73.7
164.8
196
25
G30.0
ICD-10 Finland
Alzheimer disease with early onset
779.7
164.0
168
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
11.5
162.9
327
278
SPAT1234
SPAT
Support of social functional capacity
12.5
160.6
309
240
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.7
158.0
631
1436
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
153.9
154
*
N05BA04
ATC
oxazepam; oral
3.8
150.2
780
2258
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
32.4
144.6
200
58
XA800
NOMESCO Finland
Neuropsychological investigation
69.7
143.5
172
23
F32.9
ICD-10 Finland
Depressive episode, unspecified
20.4
143.1
226
105
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
9.0
136.5
313
338
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.1
136.5
989
3654
N05AH03
ATC
olanzapine; systemic
50.3
133.2
168
31
N06AB10
ATC
escitalopram; oral
5.4
125.4
419
768
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
16.9
124.6
210
117
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.7
124.1
484
1051
N06AB04
ATC
citalopram; systemic
4.0
123.4
572
1467
N06AX26
ATC
vortioxetine; oral
23.2
115.8
175
70
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
+∞
115.6
116
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.6
114.6
628
1845
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
114.6
115
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
359.8
113.3
119
*
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
517.6
109.9
114
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
8.1
108.1
262
307
A04
ICPC
Weakness/tiredness general
3.9
100.8
471
1198
R41.0
ICD-10 Finland
Disorientation, unspecified
19.1
97.7
157
76
L28
ICPC
Limited function/disability (L)
3.3
97.6
596
1875
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
36.5
95.4
128
32
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
83.4
94.0
110
12
SPAT1254
SPAT
Administration of medicine
3.4
93.9
532
1578
R42
ICD-10 Finland
Dizziness and giddiness
2.8
89.8
713
2660
G56.0
ICD-10 Finland
Carpal tunnel syndrome
10.0
86.4
184
171
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
210.0
86.2
93
*
F05.9
ICD-10 Finland
Delirium, unspecified
166.2
83.9
92
5
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
381.0
81.0
85
*
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
727.6
78.6
81
*
WYA20
NOMESCO Finland
Home visit
30.3
78.6
110
33
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
681.3
73.7
76
*
A06AD11
ATC
lactulose; oral
3.0
72.3
480
1569
N05BA06
ATC
lorazepam; systemic, sublingual
6.5
70.9
199
286
F05.1
ICD-10 Finland
Delirium superimposed on dementia
+∞
69.5
70
*
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
23.0
69.0
104
41
F0019, G301
ICD-10 Finland
NA
+∞
68.5
69
*
Z01.9
ICD-10 Finland
Special examination, unspecified
4.4
65.6
263
569
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
65.5
66
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
11.6
65.2
128
101
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
+∞
64.5
65
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
22.5
64.0
97
39
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
107.6
63.4
72
6
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
63.3
740
3315
N06AB06
ATC
sertraline; oral
4.9
61.2
217
413
N06AX21
ATC
duloxetine; oral
4.8
60.5
218
422
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
4.7
60.1
220
433
Z2445
NOMESCO Finland
Psychologist
28.0
59.0
84
27
ACC51
NOMESCO Finland
Release of median nerve
54.5
58.9
73
12
SPAT1229
SPAT
Assessment of need for aid
3.7
57.1
279
719
G20
ICD-10 Finland
Parkinson disease
57.0
56.9
70
11
F29
ICD-10 Finland
Unspecified nonorganic psychosis
140.7
56.8
63
*
U04
ICPC
Incontinence urine
4.8
56.8
204
393
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
28.7
56.7
80
25
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
+∞
56.6
57
*
N06AX16
ATC
venlafaxine; oral
4.5
55.0
209
427
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
506.8
54.8
57
*
R55
ICD-10 Finland
Syncope and collapse
2.9
53.9
377
1258
N03AX14
ATC
levetiracetam; systemic
35.8
53.8
72
18
SPAT1246
SPAT
Screening of depression or other psychiatric problem
10.2
53.7
112
100
SPAT1172
SPAT
Guidance concerning hydration
9.6
52.9
114
108
K90
ICPC
Stroke/cerebrovascular accident
52.8
52.3
65
11
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.6
52.1
431
1590
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
129.3
52.0
58
*
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
479.4
51.9
54
*
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
246.0
51.5
55
*
SPAT1101
SPAT
Orthostatic test
4.2
50.5
208
459
N05AD01
ATC
haloperidol; systemic
9.1
50.0
111
111
AXX01
SPAT
NA
8.6
49.9
114
120
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
10.5
49.8
102
88
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
7.9
48.6
117
134
F00.00
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
48.6
49
*
SPAT1360
SPAT
Extensive global examination
3.0
48.5
308
961
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
231.8
48.5
52
*
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
+∞
47.6
48
*
N05AB03
ATC
perphenazine; systemic, rectal
21.1
47.5
73
31
I95.1
ICD-10 Finland
Orthostatic hypotension
5.6
46.5
144
234
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
26.0
46.4
67
23
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
115.7
46.2
52
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.4
45.7
179
376
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.3
45.4
179
379
F00
ICD-10 Finland
Dementia in Alzheimer disease
415.8
45.0
47
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.5
44.8
401
1538
W19
ICD-10 Finland
Unspecified fall
3.1
44.3
264
786
S01.0
ICD-10 Finland
Open wound of scalp
3.5
44.1
223
588
F34.1
ICD-10 Finland
Dysthymia
48.1
42.8
54
10
N03AF02
ATC
oxcarbazepine; oral
23.4
42.4
63
24
N02BE01
ATC
paracetamol; systemic, rectal
2.0
42.4
2342
17681
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
388.7
42.0
44
*
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
+∞
41.6
42
*
Z02.4
ICD-10 Finland
Examination for driving licence
0.5
41.4
509
7330
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
+∞
40.6
41
*
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
+∞
40.6
41
*
R51.80
ICD-10 Finland
Headache
3.0
39.9
252
781
F22.0
ICD-10 Finland
Delusional disorder
130.1
39.5
44
*
F21
ICPC
NA
32.1
39.5
54
15
F00.14
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms of mixed type
361.5
39.1
41
*
N29
ICPC
Neurological sympt/complt other
12.8
37.4
69
48
N03AF01
ATC
carbamazepine; oral, rectal
5.9
37.4
110
168
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
37.0
398
1664
Z02.7
ICD-10 Finland
Issue of medical certificate
3.6
37.0
181
464
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
+∞
36.7
37
*
F001, G301
ICD-10 Finland
NA
+∞
36.7
37
*
SPAT1252
SPAT
Overall medication plan or its review
2.8
36.4
255
843
F32
ICD-10 Finland
Depressive episode
7.5
36.0
89
107
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
35.4
343
1360
G44.2
ICD-10 Finland
Tension-type headache
3.3
34.9
194
546
C10AA01
ATC
simvastatin; oral
1.7
34.9
1515
10223
3540A
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Carpal tunnel syndrome
+∞
34.7
35
*
SPAT1304
SPAT
Counselling and guidance related to ageing
2.4
34.5
316
1216
A29
ICPC
General symptom/complaint other
2.3
34.5
353
1438
N30.0
ICD-10 Finland
Acute cystitis
2.2
34.2
378
1595
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
316.4
34.1
36
*
Z75.5
ICD-10 Finland
Holiday relief care
53.2
34.0
42
7
N06AA09
ATC
amitriptyline; systemic
2.8
34.0
235
770
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
3.1
34.0
207
622
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
4.6
33.8
125
248
S06.3
ICD-10 Finland
Focal brain injury
+∞
33.7
34
*
G72.8
ICD-10 Finland
Other specified myopathies
+∞
33.7
34
*
N17
ICPC
Vertigo/dizziness
2.3
33.1
344
1410
N05AA02
ATC
levomepromazine; systemic
9.3
32.9
71
68
R5140
NOMESCO Finland
Monitoring the use of the aid
3.7
32.7
150
364
N06AB03
ATC
fluoxetine; oral
2.7
32.6
243
833
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
13.2
32.0
58
39
N03AE01
ATC
clonazepam; systemic
4.7
32.0
114
218
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.6
31.7
261
948
F01.9
ICD-10 Finland
Vascular dementia, unspecified
40.3
31.6
41
9
R41
ICD-10 Finland
Other symptoms and signs involving cognitive functions and awareness
13.4
31.6
57
38
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
7.4
31.5
78
94
SPAT1301
SPAT
No procedures
1.7
30.9
918
5514
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
39.3
30.7
40
9
3472A
ICD-9 Finland
Cataplexy and narcolepsy[OBSTRUKTIIVINEN UNIAPNEA]
+∞
30.7
31
*
N05AD03
ATC
melperone; systemic
26.0
30.7
44
15
P29
ICPC
Psychological sympt/compl other
7.5
30.6
75
89
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.7
30.6
92
145
N04AA02
ATC
biperiden; systemic
145.8
30.0
33
*
N05CD07
ATC
temazepam; oral
2.3
30.0
312
1277
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.6
29.9
231
808
N02AA05
ATC
oxycodone; systemic
2.0
29.8
449
2154
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
8.2
29.8
69
75
N06AG02
ATC
moclobemide; oral
4.6
29.7
108
211
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
+∞
29.7
30
*
F0014, G301
ICD-10 Finland
NA
+∞
29.7
30
*
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
276.0
29.2
31
*
WX780
NOMESCO Finland
Remote monitoring CPAP
141.3
29.0
32
*
IGY02
NOMESCO Finland
Psychiatric monitoring contact
+∞
28.7
29
*
N03AX09
ATC
lamotrigine; oral
20.5
28.7
44
19
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.2
28.5
305
1264
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
11.4
28.4
55
43
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
28.1
664
3707
N28
ICPC
Limited function/disability (N)
14.7
27.8
48
29
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
25.3
27.8
40
14
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
27.7
28
*
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
+∞
27.7
28
*
F00.1
ICD-10 Finland
Dementia in Alzheimer disease with late onset
+∞
27.7
28
*
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
27.5
400
1888
SPAT1139
SPAT
Nutrition survey
4.5
27.5
103
208
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.9
27.4
432
2101
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.3
27.2
286
1172
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
5.9
27.1
79
120
S72.0
ICD-10 Finland
Fracture of neck of femur
3.6
27.0
127
315
F01.2
ICD-10 Finland
Subcortical vascular dementia
38.7
26.9
35
8
F009, G309
ICD-10 Finland
NA
+∞
26.7
27
*
85000
ICD-8 Finland
Concussion, Current or unspecified
+∞
26.7
27
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.4
26.7
238
899
SPAT1231
SPAT
Assessment of adjustments needed in living environment
7.6
26.5
64
75
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
26.4
329
1457
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
23.0
26.4
39
15
N05AX12
ATC
aripiprazole; systemic
248.2
26.3
28
*
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
128.0
26.1
29
*
R11
ICD-10 Finland
Nausea and vomiting
2.6
26.0
201
703
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
10.8
25.8
51
42
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
+∞
25.7
26
*
F05.8
ICD-10 Finland
Other delirium
238.9
25.3
27
*
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
238.9
25.3
27
*
N03AX16
ATC
pregabalin; oral
1.8
25.2
479
2485
N05CF01
ATC
zopiclone; oral
1.6
25.1
775
4649
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.5
24.9
206
747
F10.20
ICD-10 Finland
Alcohol dependence currently independent
40.4
24.8
32
7
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
6.9
24.8
64
83
N27
ICPC
Fear of neurological disease other
6.4
24.7
67
93
G04BD12
ATC
mirabegron; oral
2.0
24.6
348
1622
N06AX03
ATC
mianserin; oral
3.9
24.4
104
238
F00.19
ICD-10 Finland
Dementia in Alzheimer's disease with late onset without information about additional symptoms
229.7
24.4
26
*
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
229.7
24.4
26
*
G45.4
ICD-10 Finland
Transient global amnesia
13.6
24.2
43
28
G31.0
ICD-10 Finland
Circumscribed brain atrophy
119.0
24.2
27
*
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
39.1
23.9
31
7
G91.0
ICD-10 Finland
Communicating hydrocephalus
+∞
23.8
24
*
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
+∞
23.8
24
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
12.7
23.5
43
30
B01AC04
ATC
clopidogrel; oral
1.9
23.5
415
2097
K91
ICPC
Cerebrovascular disease
22.1
23.5
35
14
F99
ICD-10 Finland
Mental disorder, not otherwise specified
114.6
23.3
26
*
130
Kela drug reimbursment
Malignant tumour
0.4
23.1
74
1750
SPAT1307
SPAT
Psychosocial counselling and guidance
5.4
22.9
71
117
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
+∞
22.8
23
*
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
+∞
22.8
23
*
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
+∞
22.8
23
*
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
+∞
22.8
23
*
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
+∞
22.8
23
*
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.5
22.7
193
710
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
2.3
22.6
234
951
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.1
22.6
262
1123
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
22.5
702
4201
F32.1
ICD-10 Finland
Moderate depressive episode
16.4
22.5
37
20
F00.11
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms, mainly paranoidism
211.4
22.4
24
*
NA1AD
NOMESCO Finland
Cervical spine CT examination
4.6
22.3
81
159
P03
ICPC
Feeling depressed
3.9
22.1
95
219
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
12.1
22.0
41
30
R51
ICD-10 Finland
Headache
4.0
21.8
90
200
30041
ICD-8 Finland
Neuroses, Depressiva
+∞
21.8
22
*
35399
ICD-8 Finland
Sciatica
+∞
21.8
22
*
F20.9
ICD-10 Finland
Schizophrenia, unspecified
+∞
21.8
22
*
R35
ICD-10 Finland
Polyuria
2.5
21.7
184
678
R25.1
ICD-10 Finland
Tremor, unspecified
4.9
21.6
73
133
R06.5
ICD-10 Finland
Mouth breathing
3.4
21.6
111
297
M48.0
ICD-10 Finland
Spinal stenosis
1.9
21.5
328
1570
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
202.5
21.4
23
*
F01.29
ICD-10 Finland
Subcortical vascular dementia without information on additional symptoms
202.5
21.4
23
*
H02AB02
ATC
dexamethasone; systemic
0.4
21.4
96
1983
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.2
21.4
116
323
WX723
NOMESCO Finland
CPAP therapy
73.5
21.4
25
*
N05AF03
ATC
chlorprothixene; systemic
17.7
21.3
34
17
E86
ICD-10 Finland
Volume depletion
5.0
21.3
70
124
Z29
ICPC
Social problem NOS
8.7
21.3
47
48
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
16.3
21.3
35
19
N18
ICPC
Paralysis/weakness
11.8
21.3
40
30
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.2
21.1
83
177
G04BD08
ATC
solifenacin; oral
2.2
21.1
217
881
SPAT1167
SPAT
Insertion of urinary catheter
3.2
20.8
113
315
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
+∞
20.8
21
*
AA5DR
NOMESCO Finland
Brain metabolism PET with CT
+∞
20.8
21
*
F0011, G301
ICD-10 Finland
NA
+∞
20.8
21
*
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
+∞
20.8
21
*
K59.0
ICD-10 Finland
Constipation
2.6
20.6
155
533
N05AC02
ATC
thioridazine; oral
21.0
20.6
31
13
A01
ICPC
Pain general/multiple sites
2.4
20.5
187
712
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
20.4
479
2638
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.0
20.4
126
383
F41.1
ICD-10 Finland
Generalized anxiety disorder
12.0
20.4
38
28
S70.0
ICD-10 Finland
Contusion of hip
3.7
20.4
92
222
N99
ICPC
Neurological disease other
25.6
20.4
29
10
C10AA05
ATC
atorvastatin; oral
1.5
20.3
1162
7955
P15
ICPC
Chronic alcohol abuse
12.6
20.3
37
26
J01EA01
ATC
trimethoprim; systemic
1.6
20.1
616
3654
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
38.2
20.1
26
6
N05AN01
ATC
lithium; oral
27.4
20.0
28
9
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.6
19.9
609
3608
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
+∞
19.8
20
*
F0009, G300
ICD-10 Finland
NA
+∞
19.8
20
*
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
+∞
19.8
20
*
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
+∞
19.8
20
*
M54.5
ICD-10 Finland
Low back pain
1.6
19.7
634
3803
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
52.8
19.6
24
*
N87
ICPC
Parkinsonism
52.8
19.6
24
*
B01AC07
ATC
dipyridamole; systemic
3.4
19.6
98
257
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
184.8
19.5
21
*
T90.5
ICD-10 Finland
Sequelae of intracranial injury
96.8
19.4
22
*
SPAT1050
SPAT
Extensive neurological examination
4.7
19.3
68
130
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
19.2
409
2184
R4120
NOMESCO Finland
Occupational therapy
3.0
19.2
115
344
G43.9
ICD-10 Finland
Migraine, unspecified
13.1
19.0
34
23
G45.3
ICD-10 Finland
Amaurosis fugax
28.6
18.8
26
8
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
+∞
18.8
19
*
S06.2
ICD-10 Finland
Diffuse brain injury
+∞
18.8
19
*
N05BA01
ATC
diazepam; systemic, rectal
2.0
18.8
257
1177
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.4
18.7
165
619
L89
ICD-10 Finland
Decubitus ulcer and pressure area
6.3
18.7
51
72
R32
ICD-10 Finland
Unspecified urinary incontinence
3.6
18.7
88
220
N05BE01
ATC
buspirone; oral
6.4
18.7
50
69
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
18.6
399
2135
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
15.2
18.5
31
18
A02BC03
ATC
lansoprazole; oral
1.5
18.4
689
4280
R1250
NOMESCO Finland
Evaluation of functional capability
5.5
18.3
55
88
C03CA01
ATC
furosemide; systemic
1.5
18.3
774
4941
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
40.5
18.0
23
5
A27
ICPC
Fear of other disease NOS
2.5
18.0
143
509
K59.09
ICD-10 Finland
Constipation, unspecified
2.3
17.9
166
640
P76
ICPC
Depressive disorder
4.9
17.9
60
109
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
+∞
17.8
18
*
G40
ICD-10 Finland
Epilepsy
+∞
17.8
18
*
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
+∞
17.8
18
*
N19
ICPC
Speech disorder
19.8
17.7
27
12
S00.0
ICD-10 Finland
Superficial injury of scalp
4.9
17.7
59
107
F10.09
ICD-10 Finland
Alcohol intoxication UNS
61.7
17.6
21
*
N06AX12
ATC
bupropion; oral
8.8
17.5
38
38
ZXY02
NOMESCO Finland
Neuropsychologist
88.0
17.5
20
*
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
88.0
17.5
20
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
17.5
366
1940
XF606
NOMESCO Finland
Ortostatic test
10.7
17.4
34
28
F10.25
ICD-10 Finland
Alcohol dependence continuous use
33.8
17.4
23
6
N05AL01
ATC
sulpiride; systemic
10.0
17.3
35
31
R63.4
ICD-10 Finland
Abnormal weight loss
2.9
17.3
111
349
ZYB04
NOMESCO Finland
Outreach service in patient’s home or everyday environment
+∞
16.8
17
*
N05AH02
ATC
clozapine; systemic
+∞
16.8
17
*
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
+∞
16.8
17
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
+∞
16.8
17
*
R33
ICD-10 Finland
Retention of urine
2.0
16.7
241
1127
J01CA08
ATC
pivmecillinam; oral
1.5
16.2
843
5595
A04AA02
ATC
granisetron; systemic, transdermal
0.3
16.1
45
1132
188
Kela drug reimbursment
Psychosis requiring demanding treatment
+∞
15.8
16
*
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
+∞
15.8
16
*
G72.9
ICD-10 Finland
Myopathy, unspecified
+∞
15.8
16
*
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
+∞
15.8
16
*
ZXA00
NOMESCO Finland
Right side
1.5
15.8
739
4792
IGY99
NOMESCO Finland
Other psychiatric treatment contact
55.6
15.7
19
*
P99
ICPC
Psychological disorders other
13.0
15.7
28
19
S20.2
ICD-10 Finland
Contusion of thorax
2.8
15.7
102
323
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
22.5
15.7
23
9
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
0.3
15.7
24
813
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
15.6
382
2118
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
149.4
15.6
17
*
N06AA06
ATC
trimipramine; systemic
4.7
15.5
54
103
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.8
15.5
277
1395
G47.9
ICD-10 Finland
Sleep disorder, unspecified
7.1
15.5
38
47
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
15.3
843
5637
SPAT1240
SPAT
Therapeutic discussion
2.6
15.2
112
381
G51.0
ICD-10 Finland
Bell palsy
11.1
15.2
29
23
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
17.6
15.2
24
12
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
3.5
15.2
72
183
R2110
NOMESCO Finland
Giving the first information
2.2
15.1
157
641
ZY000
NOMESCO Finland
Hospital inpatient
26.4
15.0
21
7
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
15.0
697
4501
ZXD05
NOMESCO Finland
Urgent procedure
1.5
15.0
670
4295
N03AB02
ATC
phenytoin; systemic
13.5
14.9
26
17
F01.19
ICD-10 Finland
Multi-infarct dementia without information on additional symptoms
+∞
14.8
15
*
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
+∞
14.8
15
*
N01
ICPC
Headache
2.3
14.8
142
557
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
14.8
375
2097
E0000UV
ATC
NA
1.4
14.8
882
5986
Z51.88
ICD-10 Finland
Other specified medical care
3.6
14.7
68
169
J01MA02
ATC
ciprofloxacin; systemic
1.4
14.7
970
6705
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
140.5
14.6
16
*
N05BA12
ATC
alprazolam; oral
2.1
14.5
171
736
R07.3
ICD-10 Finland
Other chest pain
1.9
14.5
218
1035
A23
ICPC
Risk factor NOS
2.5
14.4
118
428
G04BD04
ATC
oxybutynin; oral, transdermal
2.2
14.2
143
573
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.2
14.2
148
603
ZY010
NOMESCO Finland
Hospital outpatient
3.5
14.1
68
175
R13
ICD-10 Finland
Dysphagia
2.2
14.1
140
560
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
20.5
14.0
21
9
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.5
14.0
585
3691
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
15.6
14.0
23
13
SPAT1260
SPAT
Consultation of another employee
1.5
13.9
466
2798
I63
ICD-10 Finland
Cerebral infarction
49.8
13.9
17
*
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
+∞
13.8
14
*
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
+∞
13.8
14
*
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
+∞
13.8
14
*
2961C
ICD-9 Finland
Affective psychoses, Manic disorder, recurrent episode[VAKAVA MASENNUSTILA,KESKIVAIKEA]
+∞
13.8
14
*
G81.9
ICD-10 Finland
Hemiplegia, unspecified
+∞
13.8
14
*
30040
ICD-8 Finland
Neuroses, Neurotico-depressiva
+∞
13.8
14
*
F05.0
ICD-10 Finland
Delirium not superimposed on dementia, so described
+∞
13.8
14
*
D12
ICPC
Constipation
2.6
13.7
103
356
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
7.6
13.7
32
37
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.3
13.6
124
475
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
13.6
673
4390
P01
ICPC
Feeling anxious/nervous/tense
3.0
13.6
80
239
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.8
13.5
87
274
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.7
13.5
60
145
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
13.5
1106
7903
N03AX12
ATC
gabapentin; oral
1.7
13.5
269
1403
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
11.6
13.5
25
19
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
13.4
931
6460
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
4.3
13.4
50
103
N30.9
ICD-10 Finland
Cystitis, unspecified
2.3
13.4
127
495
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.9
13.4
201
953
Z3226
NOMESCO Finland
Physiotherapist
1.6
13.3
414
2438
S01.1
ICD-10 Finland
Open wound of eyelid and periocular area
3.6
13.3
61
152
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
13.3
656
4276
M79.6
ICD-10 Finland
Pain in limb
1.4
13.1
766
5150
ZXD35
NOMESCO Finland
Usual procedure
3.0
13.1
78
235
A01AB09
ATC
miconazole; local oral
1.9
13.0
211
1026
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
3.3
13.0
66
178
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
13.0
192
906
AA1AD
SPAT
NA
26.4
12.9
18
6
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.0
12.9
76
227
G41.9
ICD-10 Finland
Status epilepticus, unspecified
+∞
12.9
13
*
S06.9
ICD-10 Finland
Intracranial injury, unspecified
+∞
12.9
13
*
N05AF05
ATC
zuclopenthixol; systemic
+∞
12.9
13
*
F00.13
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms, mainly depression
+∞
12.9
13
*
IAB14
NOMESCO Finland
Geriatric psychiatry consultation
+∞
12.9
13
*
G31.1
ICD-10 Finland
Senile degeneration of brain, not elsewhere classified
+∞
12.9
13
*
G99.2*M47.1
ICD-10 Finland
Spondylogenic compression of spinal cord
+∞
12.9
13
*
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
65.9
12.8
15
*
P28
ICPC
Limited function/disability (P)
65.9
12.8
15
*
P05
ICPC
Senility, feeling/behaving old
15.4
12.8
21
12
SPAT1243
SPAT
Psychiatric/psychological examination
11.1
12.7
24
19
A05
ICPC
Feeling ill
2.6
12.7
95
330
C01DA14
ATC
isosorbide mononitrate; oral
1.5
12.6
432
2601
I63.8
ICD-10 Finland
Other cerebral infarction
29.9
12.6
17
5
F43.20
ICD-10 Finland
Adaptation disorder with short-term depression
29.9
12.6
17
5
F10.24
ICD-10 Finland
Alcohol depence active use
29.9
12.6
17
5
D11
ICPC
Diarrhoea
1.9
12.6
187
882
S22.3
ICD-10 Finland
Fracture of rib
2.2
12.6
135
560
R4130
NOMESCO Finland
Speech therapy
4.9
12.6
41
74
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
4.1
12.6
49
106
W10
ICD-10 Finland
Fall on and from stairs and steps
2.5
12.5
102
369
SPAT1236
SPAT
Informing family of child’s disability
3.0
12.4
72
213
U13
ICPC
Bladder symptom/complaint other
2.6
12.4
95
332
N06AX22
ATC
agomelatine; oral
14.2
12.4
21
13
WX722
NOMESCO Finland
PEEP
3.4
12.4
59
152
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
2.2
12.3
125
504
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.7
12.3
289
1581
N04BC05
ATC
pramipexole; oral
2.1
12.3
139
590
S01.8
ICD-10 Finland
Open wound of other parts of head
5.0
12.2
39
69
P06
ICPC
Sleep disturbance
2.1
12.1
136
575
L01BC06
ATC
capecitabine; oral
0.3
12.1
26
738
R52.9
ICD-10 Finland
Pain, unspecified
1.9
12.1
179
844
G45.8
ICD-10 Finland
Other transient cerebral ischaemic attacks and related syndromes
24.9
12.1
17
6
A10AE04
ATC
insulin glargine; parenteral
1.9
12.1
194
943
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
6.3
12.1
32
45
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.8
12.0
233
1205
G50.0
ICD-10 Finland
Trigeminal neuralgia
9.2
12.0
25
24
Z28
ICPC
Limited function/disability (Z)
19.8
12.0
18
8
XA400
NOMESCO Finland
EEG
19.8
12.0
18
8
R5110
SPAT
NA
2.8
12.0
79
255
G25.0
ICD-10 Finland
Essential tremor
3.8
11.9
51
120
N06AX05
ATC
trazodone; oral
5.0
11.9
38
67
2961D
ICD-9 Finland
Affective psychoses, Manic disorder, recurrent episode[VAKAVA MASENNUSTILA,VAIKEA-ASTEINEN]
+∞
11.9
12
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
+∞
11.9
12
*
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
+∞
11.9
12
*
F0024, G301
ICD-10 Finland
NA
+∞
11.9
12
*
F00.01
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset other additional symptoms, mainly paranoidism
+∞
11.9
12
*
F31.8
ICD-10 Finland
Other bipolar affective disorders
+∞
11.9
12
*
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
+∞
11.9
12
*
PAN14
NOMESCO Finland
Plastic repair of arteries internal carotid artery
+∞
11.9
12
*
F06.9
ICD-10 Finland
Unspecified mental disorder due to brain damage and dysfunction and to physical disease
+∞
11.9
12
*
F32.0
ICD-10 Finland
Mild depressive episode
5.3
11.9
36
60
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.1
11.8
142
617
J01DB01
ATC
cefalexin; oral
1.4
11.8
1926
15192
AAF00
NOMESCO Finland
Ventriculostomy
114.1
11.8
13
*
I62.0
ICD-10 Finland
Nontraumatic subdural haemorrhage
114.1
11.8
13
*
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
114.1
11.8
13
*
E000001
ATC
NA
1.5
11.7
401
2409
R00.1
ICD-10 Finland
Bradycardia, unspecified
2.4
11.7
100
371
B01AA03
ATC
warfarin; systemic
1.5
11.6
532
3404
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
0.3
11.6
32
810
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.4
11.6
594
3883
A02BC05
ATC
esomeprazole; systemic
1.4
11.6
891
6259
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
11.5
138
602
H53.1
ICD-10 Finland
Subjective visual disturbances
2.2
11.4
119
486
A02BC01
ATC
omeprazole; systemic
1.4
11.3
639
4252
SPAT1125
SPAT
Stoma care and guidance
3.6
11.3
51
126
PA7BD
NOMESCO Finland
CT angiography of neck and brain
6.9
11.3
28
36
N06AB08
ATC
fluvoxamine; oral
3.6
11.3
50
122
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
23.4
11.2
16
6
T08
ICPC
Weight loss
3.7
11.2
49
118
R47.1
ICD-10 Finland
Dysarthria and anarthria
15.8
11.1
18
10
E87.0
ICD-10 Finland
Hyperosmolality and hypernatraemia
15.8
11.1
18
10
-2
ICPC
NA
15.8
11.1
18
10
SPAT1104
SPAT
Monitoring of emergency patient
1.9
11.1
160
748
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.4
11.1
93
342
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.6
11.1
82
284
SPAT1263
SPAT
Sampling
1.3
11.1
1007
7246
Z2446
NOMESCO Finland
Social worker
2.2
11.0
107
426
N06AA04
ATC
clomipramine; systemic
5.5
11.0
32
51
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
10.9
1721
13408
N04BD01
ATC
selegiline; oral
57.0
10.9
13
*
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
+∞
10.9
11
*
AA400
NOMESCO Finland
Electroconvulsive therapy
+∞
10.9
11
*
AAF15
NOMESCO Finland
Ventriculoatrial shunt
+∞
10.9
11
*
F31.20
ICD-10 Finland
Bipolar disorder, manic episode with mood-congruent psychotic symptoms
+∞
10.9
11
*
IER02
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, group
+∞
10.9
11
*
IBZ07
NOMESCO Finland
Neurological assessment in psychiatry
+∞
10.9
11
*
2961E
ICD-9 Finland
Affective psychoses, Manic disorder, recurrent episode[VAKAVA MASENNUSTILA,VAIKEA-ASTEINEN+PSYKOOT PIIRTEI]
+∞
10.9
11
*
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
+∞
10.9
11
*
P72
ICPC
Schizophrenia
105.3
10.8
12
*
S09.9
ICD-10 Finland
Unspecified injury of head
6.1
10.8
29
42
G04BD07
ATC
tolterodine; oral
2.0
10.7
135
601
SPAT1276
SPAT
Outlining of treatment with patient or their family members
2.9
10.7
63
190
UKC02
NOMESCO Finland
Cystoscopy
1.5
10.6
453
2854
Y94.0
ICD-10 Finland
Accident at home
3.4
10.6
51
133
AA1CG
SPAT
NA
7.8
10.6
24
27
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
7.3
10.6
25
30
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
10.6
371
2240
WX402
NOMESCO Finland
General anaesthesia
0.6
10.5
168
2360
SPAT1262
SPAT
Handing over of treatment supplies
1.5
10.5
456
2885
A46
ICD-10 Finland
Erysipelas
1.6
10.4
318
1857
R1250
SPAT
NA
7.5
10.4
24
28
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.5
10.3
48
122
B03BA03
ATC
hydroxocobalamin; parenteral
1.9
10.3
155
736
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
4.5
10.3
36
71
F01.30
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without additional symptoms
38.0
10.2
13
*
F22.9
ICD-10 Finland
Persistent delusional disorder, unspecified
38.0
10.2
13
*
Z71.8
ICD-10 Finland
Other specified counselling
1.4
10.2
479
3071
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
10.1
904
6464
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
3.5
10.1
46
115
G04CA02
ATC
tamsulosin; oral
1.4
10.1
669
4562
G04BD09
ATC
trospium; oral
2.6
10.1
72
245
S42.2
ICD-10 Finland
Fracture of upper end of humerus
2.1
10.1
116
496
I50.9
ICD-10 Finland
Heart failure, unspecified
1.5
10.0
312
1833
AA1AA
NOMESCO Finland
Head X-ray examination
5.3
10.0
30
50
F43.29
ICD-10 Finland
Adaptation disorder UNS
24.6
10.0
14
5
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
52.6
10.0
12
*
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
13.6
10.0
17
11
Z73.6
ICD-10 Finland
Limitation of activities due to disability
5.1
10.0
31
54
N06AB05
ATC
paroxetine; oral
2.6
9.9
71
242
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.9
9.9
32
58
R47.8
ICD-10 Finland
Other and unspecified speech disturbances
10.4
9.9
19
16
3074A
ICD-9 Finland
Special symptoms or syndromes not elsewhere classified, Specific disorders of sleep of nonorganic origin[UNIHÄIRIÖ]
+∞
9.9
10
*
F25.00
ICD-10 Finland
Schizoaffective syndrome, manic type with only simultaneous bipolar and schizophrenic symptoms
+∞
9.9
10
*
F00.09
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset information on additional symptoms is lacking
+∞
9.9
10
*
N05BA09
ATC
clobazam; oral
+∞
9.9
10
*
G91.1
ICD-10 Finland
Obstructive hydrocephalus
+∞
9.9
10
*
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
+∞
9.9
10
*
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
+∞
9.9
10
*
2989X
ICD-9 Finland
Other nonorganic psychoses, Unspecified psychosis
+∞
9.9
10
*
N03AX18
ATC
lacosamide; systemic
+∞
9.9
10
*
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
+∞
9.9
10
*
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
9.9
843
5982
L75
ICPC
Fracture: femur
3.9
9.9
40
91
A11
ICPC
Chest pain NOS
1.7
9.9
196
1021
Z60.8
ICD-10 Finland
Other problems related to social environment
96.5
9.8
11
*
R60.0
ICD-10 Finland
Localized oedema
1.6
9.8
255
1433
A02BA02
ATC
ranitidine; systemic
1.4
9.8
445
2834
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
1.7
9.8
217
1168
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
0.4
9.8
31
735
N05CD02
ATC
nitrazepam; oral
3.8
9.8
41
96
K59.1
ICD-10 Finland
Functional diarrhoea
2.1
9.7
112
482
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.7
9.7
208
1110
K08.3
ICD-10 Finland
Retained dental root
1.9
9.7
152
734
SPAT1138
SPAT
Guidance concerning bowel function
4.2
9.5
35
73
Z03
ICPC
Housing/neighbourhood problem
16.5
9.5
15
8
R44.3
ICD-10 Finland
Hallucinations, unspecified
16.5
9.5
15
8
S28
ICPC
Limited function/disability (S)
7.4
9.5
22
26
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
5.9
9.5
26
39
N06AA12
ATC
doxepin; systemic
2.3
9.5
89
350
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
2.4
9.4
76
276
N06AA10
ATC
nortriptyline; systemic
4.5
9.4
32
62
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
9.4
547
3648
AA5PD
NOMESCO Finland
CT examination of brain pefusion
35.0
9.3
12
*
G04BD11
ATC
fesoterodine; oral
2.3
9.3
87
339
G45
ICD-10 Finland
Transient cerebral ischaemic attacks and related syndromes
11.5
9.3
17
13
G50.1
ICD-10 Finland
Atypical facial pain
6.7
9.3
23
30
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
9.3
1114
8276
KMAK
NOMESCO Finland
NA
1.3
9.3
977
7132
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.7
9.3
177
910
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.5
9.2
327
1976
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
9.2
712
4968
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
9.2
879
6330
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
9.2
269
1558
F80.1
ICD-10 Finland
Expressive language disorder
22.8
9.1
13
5
N05AA01
ATC
chlorpromazine; systemic, rectal
22.8
9.1
13
5
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
14.6
9.1
15
9
J01DA01
ATC
[U] cefalexin; systemic
1.3
9.1
1340
10221
M03BX01
ATC
baclofen; systemic
6.5
9.1
23
31
F01
ICD-10 Finland
Vascular dementia
17.5
9.1
14
7
Z13.3
ICD-10 Finland
Special screening examination for mental and behavioural disorders
48.2
9.1
11
*
I69.8
ICD-10 Finland
Sequelae of other and unspecified cerebrovascular diseases
48.2
9.1
11
*
R44.0
ICD-10 Finland
Auditory hallucinations
48.2
9.1
11
*
G56.2
ICD-10 Finland
Lesion of ulnar nerve
8.0
9.1
20
22
SPAT1285
SPAT
Provision of consultation response
1.9
9.0
131
616
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.6
8.9
269
1567
G21.1
ICD-10 Finland
Other drug-induced secondary parkinsonism
+∞
8.9
9
*
F0012, G301
ICD-10 Finland
NA
+∞
8.9
9
*
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
+∞
8.9
9
*
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
+∞
8.9
9
*
F60.9
ICD-10 Finland
Personality disorder, unspecified
+∞
8.9
9
*
F00.12
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset, other additional symptoms, mainly hallucinations
+∞
8.9
9
*
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
+∞
8.9
9
*
LAITO
NOMESCO Finland
NA
+∞
8.9
9
*
G40.10
ICD-10 Finland
Simple partial seizures
+∞
8.9
9
*
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
+∞
8.9
9
*
S01
ICD-10 Finland
Open wound of head
4.2
8.9
33
70
M03BX02
ATC
tizanidine; oral
1.3
8.8
1139
8528
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.6
8.8
30
58
R40.2
ICD-10 Finland
Coma, unspecified
7.6
8.8
20
23
S72.1
ICD-10 Finland
Pertrochanteric fracture
3.0
8.8
50
148
N80
ICPC
Head injury other
4.2
8.7
32
67
R60.9
ICD-10 Finland
Oedema, unspecified
2.0
8.7
106
466
EBA30
NOMESCO Finland
Excision of root of tooth
1.9
8.7
127
601
SPAT1281
SPAT
Other administrative function
1.7
8.7
188
1004
R25.2
ICD-10 Finland
Cramp and spasm
3.1
8.7
46
131
NF1AA
NOMESCO Finland
Hip X-ray examination
1.6
8.6
232
1315
M02AA07
ATC
piroxicam; topical
1.3
8.6
875
6339
I95.9
ICD-10 Finland
Hypotension, unspecified
4.0
8.6
33
72
A02BX02
ATC
sucralfate; oral
2.1
8.6
92
383
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
8.6
236
1345
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
8.6
676
4724
C07AA05
ATC
propranolol; systemic
1.5
8.5
298
1797
SPAT1251
SPAT
Organisation of medication
2.3
8.5
75
287
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.7
8.5
175
922
XA402
NOMESCO Finland
ENMG
4.0
8.5
33
73
Z20.8
ICD-10 Finland
Contact with and exposure to other communicable diseases
2.4
8.5
69
254
N43
ICPC
Neurological, Other diagnostic procedure
6.2
8.5
22
31
R01AD09
ATC
mometasone; nasal
1.3
8.5
780
5574
Z50.1
ICD-10 Finland
Other physical therapy
1.9
8.5
115
529
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
2.6
8.5
58
194
Z51.5
ICD-10 Finland
Palliative care
1.7
8.5
194
1054
E66.8
ICD-10 Finland
Other obesity
3.1
8.4
44
124
C07AB07
ATC
bisoprolol; oral
1.3
8.4
1287
9831
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.6
8.4
247
1433
K92.0
ICD-10 Finland
Haematemesis
2.9
8.3
50
155
WX212
NOMESCO Finland
Femoral plexus blockade
2.9
8.3
49
150
XKD06
NOMESCO Finland
Physiologic investigation of micturition
2.3
8.3
72
272
XA420
NOMESCO Finland
Extensive sleep examination
10.0
8.3
16
14
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
3.2
8.3
42
116
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
16.3
8.3
13
7
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
0.4
8.3
26
619
N03AX11
ATC
topiramate; oral
8.8
8.2
17
17
R4110
NOMESCO Finland
Physiotherapy
1.3
8.2
622
4319
L29.9
ICD-10 Finland
Pruritus, unspecified
3.0
8.1
46
135
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.6
8.1
208
1168
D01AC02
ATC
miconazole; topical
1.7
8.0
169
897
F51.0
ICD-10 Finland
Nonorganic insomnia
1.7
8.0
162
848
M01AX17
ATC
nimesulide; oral
1.3
8.0
584
4027
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.7
8.0
54
178
F45.0
ICD-10 Finland
Somatization disorder
78.9
7.9
9
*
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
78.9
7.9
9
*
183
Kela drug reimbursment
Lamotrigin and topiramate
+∞
7.9
8
*
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
+∞
7.9
8
*
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
+∞
7.9
8
*
F0013, G301
ICD-10 Finland
NA
+∞
7.9
8
*
ZXY03
NOMESCO Finland
Occupational therapist
+∞
7.9
8
*
F23.3
ICD-10 Finland
Other acute predominantly delusional psychotic disorders
+∞
7.9
8
*
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
+∞
7.9
8
*
RT250
NOMESCO Finland
NA
+∞
7.9
8
*
G24.9
ICD-10 Finland
Dystonia, unspecified
+∞
7.9
8
*
AAA20
NOMESCO Finland
Insertion of intraventricular pressure monitoring device
+∞
7.9
8
*
34609
ICD-8 Finland
Migraine, Unspecified
+∞
7.9
8
*
I61
ICD-10 Finland
Intracerebral haemorrhage
+∞
7.9
8
*
IAB01
NOMESCO Finland
Psychiatric pharmacotherapy consultation
+∞
7.9
8
*
AAD12
NOMESCO Finland
Drainage of subdural fluid
+∞
7.9
8
*
29530
ICD-8 Finland
Schizophrenia, Paranoid type
+∞
7.9
8
*
IGP01
NOMESCO Finland
Psychiatric family contact
+∞
7.9
8
*
PA2VT
NOMESCO Finland
Intravascular evacuation of brain artery embolus
+∞
7.9
8
*
F10.73
ICD-10 Finland
Residual or late-onset psychosis caused by alcohol dementia
+∞
7.9
8
*
30300
ICD-8 Finland
Alcoholism, Episodic excessive drinking
+∞
7.9
8
*
G40.6
ICD-10 Finland
Grand mal seizures, unspecified (with or without petit mal)
+∞
7.9
8
*
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
+∞
7.9
8
*
F61.0
ICD-10 Finland
Mixed personality disorders
+∞
7.9
8
*
F25.10
ICD-10 Finland
Schizoaffective syndrome, depressive type with only concomitant bipolar and schizophrenic symptoms
+∞
7.9
8
*
F32.01
ICD-10 Finland
Mild depressive episode with somatic syndrome
14.3
7.9
13
8
L76
ICPC
Fracture: other
2.4
7.9
67
252
A03FA02
ATC
cisapride; oral, rectal
1.7
7.9
169
903
SPAT1284
SPAT
Extensive health certificate
2.6
7.9
55
187
E87.6
ICD-10 Finland
Hypokalaemia
2.3
7.9
69
262
A10AE05
ATC
insulin detemir; parenteral
2.0
7.8
102
462
Z08
ICPC
Social welfare problem
10.1
7.8
15
13
R30.0
ICD-10 Finland
Dysuria
2.3
7.8
72
282
81
HP
Angiography of the heart and coronary arteries
1.7
7.8
175
948
RS222
NOMESCO Finland
NA
4.7
7.7
25
47
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
2.2
7.6
76
310
R1260
NOMESCO Finland
Evaluation of communicative skills
3.7
7.6
32
77
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
2.8
7.6
48
153
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
7.6
261
1570
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
29.2
7.6
10
*
SPAT1297
SPAT
Other function in accordance with speech therapy nomenclature
29.2
7.6
10
*
G62.8
ICD-10 Finland
Other specified polyneuropathies
29.2
7.6
10
*
F39
ICD-10 Finland
Unspecified mood [affective] disorder
29.2
7.6
10
*
G44.0
ICD-10 Finland
Cluster headache syndrome
29.2
7.6
10
*
A10BB01
ATC
glibenclamide; oral
2.0
7.6
98
445
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.6
7.5
53
181
Z46.9
ICD-10 Finland
Fitting and adjustment of unspecified device
3.4
7.5
35
91
D07AA02
ATC
hydrocortisone; topical
1.5
7.5
226
1317
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
7.5
946
7018
HA1RA
SPAT
NA
0.1
7.5
*
260
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
1.9
7.5
109
514
4471
FHL
Pharyngoplasty
15.0
7.5
12
7
ACC19
NOMESCO Finland
Transcision of peripheral nerve: other or unspecified
19.3
7.5
11
5
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
19.3
7.5
11
5
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
4.5
7.4
25
49
A69
ICPC
General and Unspecified, Other reason for encounter NEC
2.6
7.4
54
187
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
7.3
561
3890
C09AA05
ATC
ramipril; oral
1.3
7.3
675
4808
A10BH05
ATC
linagliptin; oral
1.8
7.3
128
642
H53.4
ICD-10 Finland
Visual field defects
3.5
7.3
33
84
R20.2
ICD-10 Finland
Paraesthesia of skin
2.1
7.3
83
358
R50.9
ICD-10 Finland
Fever, unspecified
1.5
7.3
270
1648
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
0.3
7.3
20
503
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
4.2
7.3
26
54
HMAK
NOMESCO Finland
NA
0.6
7.2
98
1438
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.7
7.2
143
746
I67.2
ICD-10 Finland
Cerebral atherosclerosis
39.4
7.2
9
*
N04BC04
ATC
ropinirole; oral
11.4
7.2
13
10
R47.0
ICD-10 Finland
Dysphasia and aphasia
11.4
7.2
13
10
R23.8
ICD-10 Finland
Other and unspecified skin changes
0.7
7.2
227
2786
A02BC02
ATC
pantoprazole; systemic
1.2
7.2
1530
12055
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
5.0
7.2
22
39
Z3231
NOMESCO Finland
Registered nurse
1.3
7.2
610
4295
SPAT1279
SPAT
Preparation of immediate hospitalisation
4.5
7.1
24
47
R54
ICD-10 Finland
Senility
13.2
7.1
12
8
H02AA02
ATC
fludrocortisone; oral
5.5
7.1
20
32
A04AA55
ATC
palonosetron, combinations; systemic
0.2
7.1
7
303
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
7.1
166
911
N05CF02
ATC
zolpidem; oral
1.4
7.1
288
1793
R29.6
ICD-10 Finland
Tendency to fall, not elsewhere classified
8.2
7.1
15
16
SPAT1094
SPAT
Continuous Positive Airway Pressure
21.9
7.1
10
*
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
5.8
7.0
19
29
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
3.3
7.0
34
92
N88
ICPC
Epilepsy
70.1
7.0
8
*
I69
ICD-10 Finland
Sequelae of cerebrovascular disease
70.1
7.0
8
*
F00.24
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type other additional symptoms of mixed type
70.1
7.0
8
*
F02.09*G31.0
ICD-10 Finland
Dementia in Pick's disease without information on additional symptoms
70.1
7.0
8
*
H02BX01
ATC
methylprednisolone, combinations; systemic
1.7
7.0
127
647
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.1
7.0
79
341
JN4AD
NOMESCO Finland
Body CT examination
0.6
7.0
98
1425
Z01.7
ICD-10 Finland
Laboratory examination
1.5
7.0
248
1501
I50.0
ICD-10 Finland
Congestive heart failure
1.7
7.0
152
817
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.7
6.9
135
700
Z3229
NOMESCO Finland
Other healthcare associate professional
1.6
6.9
179
1007
G63.2
ICD-10 Finland
Diabetic polyneuropathy
10.4
6.9
13
11
TPX22
NOMESCO Finland
Intravenous arterial thrombolysis
10.4
6.9
13
11
A86
ICD-10 Finland
Unspecified viral encephalitis
10.4
6.9
13
11
AA1XD
NOMESCO Finland
Other special CT of head and brain
10.4
6.9
13
11
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.7
6.9
130
669
S06.8
ICD-10 Finland
Other intracranial injuries
+∞
6.9
7
*
4380A
ICD-9 Finland
Late effects of cerebrovascular disease[SEQUELAE MORBI CEREBROVASCULARIS]
+∞
6.9
7
*
IHZ08
SPAT
NA
+∞
6.9
7
*
ZYD01
NOMESCO Finland
Emergency clinic
+∞
6.9
7
*
30680
ICD-8 Finland
Special symptoms not elsewhere classified, Cephalalgia
+∞
6.9
7
*
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
+∞
6.9
7
*
F0021, G301
ICD-10 Finland
NA
+∞
6.9
7
*
I67.4
ICD-10 Finland
Hypertensive encephalopathy
+∞
6.9
7
*
ACC53
NOMESCO Finland
Release of ulnar nerve
+∞
6.9
7
*
43090
ICD-8 Finland
Subarachnoid haemorrhage, Postaneurysma sacculare, hypertonia non indicata
+∞
6.9
7
*
G35
ICD-10 Finland
Multiple sclerosis
+∞
6.9
7
*
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
+∞
6.9
7
*
F33.3
ICD-10 Finland
Recurrent depressive disorder, current episode severe with psychotic symptoms
+∞
6.9
7
*
F20.5
ICD-10 Finland
Residual schizophrenia
+∞
6.9
7
*
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
+∞
6.9
7
*
29999
ICD-8 Finland
Unspecified psychosis
+∞
6.9
7
*
ICC03
NOMESCO Finland
Psychiatric treatment plan, transfer to psychiatric ward
+∞
6.9
7
*
AAD05
NOMESCO Finland
Evacuation of acute subdural haematoma
+∞
6.9
7
*
G46.4*I67.9
ICD-10 Finland
Cerebellar stroke syndrome
+∞
6.9
7
*
G46.8*I67.9
ICD-10 Finland
Other vascular syndromes of brain in cerebrovascular diseases
+∞
6.9
7
*
I60.1
ICD-10 Finland
Subarachnoid haemorrhage from middle cerebral artery
+∞
6.9
7
*
I60.2
ICD-10 Finland
Subarachnoid haemorrhage from anterior communicating artery
+∞
6.9
7
*
P98
ICPC
Psychosis NOS/other
+∞
6.9
7
*
29599
ICD-8 Finland
Schizophrenia, Unspecified type
+∞
6.9
7
*
L03AA14
ATC
lipegfilgrastim; parenteral
0.2
6.9
6
281
N05AF01
ATC
flupentixol; systemic
4.0
6.9
26
57
U05
ICPC
Urination problems other
1.8
6.9
119
597
SPAT1244
SPAT
Occupational therapy
4.5
6.9
23
45
Z2221
NOMESCO Finland
Medical doctor
1.3
6.8
616
4371
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
0.4
6.8
25
555
2780A
ICD-9 Finland
Obesity and other hyperalimentation, Obesity
5.9
6.8
18
27
XG466
NOMESCO Finland
Sleep oxymetry
3.2
6.8
33
90
A03FA01
ATC
metoclopramide; systemic, rectal
0.7
6.8
302
3497
A03CA02
ATC
clidinium and psycholeptics; oral
1.7
6.8
137
723
A10BX01
ATC
guar gum; systemic
1.9
6.7
101
483
103
Kela drug reimbursment
Diabetes, insulin-treated
1.3
6.7
626
4457
XCK10
NOMESCO Finland
Photography of fundus of eye
1.5
6.7
263
1627
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
5.4
6.7
19
31
Z75.0
ICD-10 Finland
Medical services not available in home
26.3
6.7
9
*
F33.8
ICD-10 Finland
Other recurrent depressive disorders
26.3
6.7
9
*
ZXA05
NOMESCO Finland
Left side
1.3
6.7
647
4632
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.0
6.7
76
329
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.6
459
3134
A02BA04
ATC
nizatidine; systemic
1.6
6.6
166
928
S40.0
ICD-10 Finland
Contusion of shoulder and upper arm
2.2
6.6
61
240
WF049
NOMESCO Finland
Radiotherapy of metastasis
0.4
6.6
27
575
D10
ICPC
Vomiting
2.5
6.5
47
164
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
6.0
6.5
17
25
S00.8
ICD-10 Finland
Superficial injury of other parts of head
3.4
6.5
29
74
U29
ICPC
Urinary symptom/complaint other
2.1
6.5
70
295
SPAT1157
SPAT
Guidance concerning treatment of mouth and mucous membranes
3.1
6.5
33
93
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
3.1
6.5
33
93
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
6.4
644
4628
F41.09
ICD-10 Finland
UNS Panic Syndrome
5.4
6.4
18
29
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
5.4
6.4
18
29
S72.4
ICD-10 Finland
Fracture of lower end of femur
5.4
6.4
18
29
E16.0
ICD-10 Finland
Drug-induced hypoglycaemia without coma
8.8
6.4
13
13
S22.4
ICD-10 Finland
Multiple fractures of ribs
2.7
6.4
42
139
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.4
6.4
49
177
AA1BD
NOMESCO Finland
Extensive CT of head and brain
2.4
6.4
52
194
F41.3
ICD-10 Finland
Other mixed anxiety disorders
35.0
6.3
8
*
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
35.0
6.3
8
*
Z72.1
ICD-10 Finland
Alcohol use
5.7
6.3
17
26
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.7
6.3
39
125
115
Kela drug reimbursment
Breast cancer
0.6
6.3
98
1388
L84
ICD-10 Finland
Corns and callosities
2.1
6.3
71
306
SPAT1042
SPAT
Guidance concerning balance maintenance
5.3
6.3
18
30
I50
ICD-10 Finland
Heart failure
2.0
6.2
71
308
WX892
NOMESCO Finland
Monitored bed care
1.6
6.2
156
871
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.1
6.2
64
266
SPAT1294
SPAT
Other function in accordance with health social work nomenclature
2.4
6.2
51
191
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
19.7
6.2
9
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
1.9
6.2
91
434
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
3.2
6.2
30
82
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
2.7
6.2
38
122
SPAT1153
SPAT
Removal of sutures
0.8
6.2
643
6677
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
6.2
575
4090
XCH00
NOMESCO Finland
Eye pressure measurement
0.5
6.2
35
662
P27
ICPC
Fear of mental disorder
8.1
6.2
13
14
S52.5
ICD-10 Finland
Fracture of lower end of radius
1.5
6.1
235
1447
7865A
ICD-9 Finland
Symptoms involving respiratory system and other chest symptoms, Chest pain
2.5
6.1
44
154
J01MA06
ATC
norfloxacin; oral
1.4
6.1
278
1768
P74
ICPC
Anxiety disorder/anxiety state
3.7
6.1
25
60
SPAT1127
SPAT
Enema
4.3
6.1
21
43
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
61.4
6.1
7
*
Z98.2
ICD-10 Finland
Presence of cerebrospinal fluid drainage device
61.4
6.1
7
*
G93.0
ICD-10 Finland
Cerebral cysts
61.4
6.1
7
*
ZXY01
NOMESCO Finland
Chief Physician, Head of Department or Deputy Chief Physician
61.4
6.1
7
*
G44.1
ICD-10 Finland
Vascular headache, not elsewhere classified
61.4
6.1
7
*
S02.11
ICD-10 Finland
Fracture of base of skull, open
61.4
6.1
7
*
IGV01
NOMESCO Finland
Psychiatric network contact
61.4
6.1
7
*
F31
ICD-10 Finland
Bipolar affective disorder
61.4
6.1
7
*
F22.8
ICD-10 Finland
Other persistent delusional disorders
61.4
6.1
7
*
E44.1
ICD-10 Finland
Mild protein-energy malnutrition
61.4
6.1
7
*
PJA12
NOMESCO Finland
Sentinel node biopsy
0.6
6.1
91
1300
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
0.5
6.0
52
859
R44.1
ICD-10 Finland
Visual hallucinations
10.7
6.0
11
9
UJF32
NOMESCO Finland
Coloscopy
1.3
6.0
618
4451
R07.2
ICD-10 Finland
Precordial pain
2.4
6.0
49
182
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
1.8
6.0
97
478
R15
ICD-10 Finland
Faecal incontinence
2.1
6.0
60
247
N30
ICD-10 Finland
Cystitis
1.6
6.0
133
721
L03AA02
ATC
filgrastim; parenteral
0.4
6.0
20
461

Mortality – FinRegistry

↥

Association

Association between endpoint AD_LO_EXMORE and mortality.

Females

Parameter HR [95% CI] p-value
AD_LO_EXMORE 2.157 [1.96, 2.37] < 0.001
Birth year 0.991 [0.98, 1.0] 0.03

During the follow-up period (1.1.1998 — 31.12.2019), 51753 out of 77066 females with AD_LO_EXMORE died.

Males

Parameter HR [95% CI] p-value
AD_LO_EXMORE 2.456 [2.15, 2.8] < 0.001
Birth year 0.984 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 28916 out of 40995 males with AD_LO_EXMORE died.

Mortality risk

Mortality risk for people of age

years, who have AD_LO_EXMORE.

N-year risk Females Males
1 0.192% 0.398%
5 1.076% 2.257%
10 2.645% 5.951%
15 4.815% 10.915%
20 8.022% 18.077%

Relationships between endpoints

↥

Index endpoint: AD_LO_EXMORE – Alzheimer’s disease (Late onset), excluding more controls

GWS hits: 20

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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