Risteys · O15_COMPLIC

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule only females	293373
2. Check conditions None	293373
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — O85-O92 Cause of death: ICD-10 — O85-O92 2 out of 7 registries used, show all original rules.	6711
4. Check minimum number of events None	6711
5. Include endpoints O15_PUERP_SEPSIS O15_PUERP_INFECT_OTHER O15_VENOUS_COMPLIC O15_OBSTET_EMBOL O15_PUERP_ANEST_COMPL O15_PUERP_COMPL_NAS O15_BIRTH_BREAT_INFECT O15_BREAST_LACT_OTHER_DIS	12286
6. Filter based on genotype QC (FinnGen only)	12286

	All	Female	Male
Number of individuals
Whole population	85667	85667	-
Only index persons	83576	83576	-
Unadjusted period prevalence (%)
Whole population	2.45	2.45	-
Only index persons	3.07	3.07	-
Median age at first event (years)
Whole population	-	28.24	-
Only index persons	-	28.24	-

	All	Female	Male
Number of individuals	12286	12286	-
Unadjusted period prevalence (%)	4.19	4.19	-
Median age at first event (years)	28.66	28.66	-

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
11013: Matched controls
110129

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

67009

ICD-8 Finland

Sepsis of childbirth and the puerperium, Unspecified

+∞

323.0

414

6700A

ICD-9 Finland

Major puerperal infection

+∞

323.0

694

67000

ICD-8 Finland

Sepsis of childbirth and the puerperium, Endometritis

+∞

323.0

1527

O86.1

ICD-10 Finland

Other infection of genital tract following delivery

599.6

323.0

886

O86.8

ICD-10 Finland

Other specified puerperal infections

1009.4

323.0

390

O86.0

ICD-10 Finland

Infection of obstetric surgical wound

137.5

323.0

932

O91.2

ICD-10 Finland

Nonpurulent mastitis associated with childbirth

19.5

323.0

807

444

O86.4

ICD-10 Finland

Pyrexia of unknown origin following delivery

1961.2

323.0

359

O85

ICD-10 Finland

Puerperal sepsis

734.5

323.0

1125

67008

ICD-8 Finland

Sepsis of childbirth and the puerperium, Alia definita

+∞

323.0

1030

O92.7

ICD-10 Finland

Other and unspecified disorders of lactation

263.4

300.6

307

O90.9

ICD-10 Finland

Complication of the puerperium, unspecified

455.4

268.9

268

67299

ICD-8 Finland

Pyrexia of unknown origin during the puerperium

+∞

268.8

257

MA2AE

NOMESCO Finland

Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus

2.3

268.7

3311

17511

6748X

ICD-9 Finland

Other and unspecified complications of the puerperium, not elsewhere classified, Other

+∞

266.7

255

MA2HE

NOMESCO Finland

Detailed morfological ultrasound examination of fetus

2.2

235.3

3283

18149

P01AB01

ATC

metronidazole; oral, rectal

1.9

231.0

5435

36923

Z36.3

ICD-10 Finland

Antenatal screening for malformations using ultrasound and other physical methods

2.0

230.0

4456

28122

Z39.2

ICD-10 Finland

Routine postpartum follow-up

2.2

220.4

2892

15473

O86.2

ICD-10 Finland

Urinary tract infection following delivery

715.4

214.4

211

O90.1

ICD-10 Finland

Disruption of perineal obstetric wound

106.3

209.0

229

MCA10

NOMESCO Finland

Lower uterine segment caesarean section

2.3

196.9

2176

10666

Z34.8

ICD-10 Finland

Supervision of other normal pregnancy

2.1

196.7

2934

16441

O90.8

ICD-10 Finland

Other complications of the puerperium, not elsewhere classified

225.1

193.1

199

O47.0

ICD-10 Finland

False labour before 37 completed weeks of gestation

2.3

183.0

1887

8905

MA2JE

NOMESCO Finland

Ultrasound screening of fetal nuchal translucency

2.3

176.3

1923

9311

SPAT1197

SPAT

Extensive health check-up of expecting family

2.0

176.1

2757

15633

O99.80

ICD-10 Finland

The fear of childbirth

2.8

168.3

1184

4495

Z32.1

ICD-10 Finland

Pregnancy confirmed

2.2

165.3

2074

10674

SPAT1379

SPAT

Health check-up of pregnant person

2.0

164.1

2405

13218

O90.2

ICD-10 Finland

Haematoma of obstetric wound

815.5

164.1

161

W78

ICPC

Pregnancy

1.9

159.1

2974

17907

67801

ICD-8 Finland

Mastitis and other disorders of lactation, Mastitis

+∞

158.7

152

6752A

ICD-9 Finland

Infections of the breast and nipple associated with childbirth, Nonpurulent mastitis

+∞

155.6

149

SPAT1380

SPAT

Postpartum check-up

2.1

152.9

2083

11064

O34.2

ICD-10 Finland

Maternal care due to uterine scar from previous surgery

2.6

150.7

1261

5286

Z37.0

ICD-10 Finland

Single live birth

2.1

143.4

1972

10480

O91.1

ICD-10 Finland

Abscess of breast associated with childbirth

48.8

141.6

173

Z35.8

ICD-10 Finland

Supervision of other high-risk pregnancies

2.1

138.6

1773

9124

ZXD05

NOMESCO Finland

Urgent procedure

1.7

138.0

3632

24252

WX307

NOMESCO Finland

Obstetric epidural analgesia

2.1

135.5

1725

8852

O90.0

ICD-10 Finland

Disruption of caesarean section wound

328.5

129.8

131

Z34.0

ICD-10 Finland

Supervision of normal first pregnancy

1.9

128.9

2449

14641

O86.3

ICD-10 Finland

Other genitourinary tract infections following delivery

323.3

127.7

129

J01DB01

ATC

cefalexin; oral

1.8

125.3

9103

79869

O89.4

ICD-10 Finland

Spinal and epidural anaesthesia-induced headache during the puerperium

+∞

115.8

111

O24.4

ICD-10 Finland

Diabetes mellitus arising in pregnancy

2.0

115.5

1642

8767

MA2DE

NOMESCO Finland

Detailed ultrasound examination of fetus including color doppler method

2.0

115.1

1646

8805

O82.10

ICD-10 Finland

Delivery by emergency caesarean section

2.3

109.3

1138

5292

LC2BE

NOMESCO Finland

Transvaginal ultrasound examination of uterus, parametria and lower abdomen

1.6

106.0

4579

34289

MA1AE

NOMESCO Finland

Ultrasound examination of early pregnancy (before 12. postmenstrual week)

1.8

102.5

1914

11254

MWA00

NOMESCO Finland

Repair of wound dehiscence in obstetric surgery

31.8

98.9

132

Z3232

NOMESCO Finland

Midwife

1.9

98.8

1705

9739

O72.2

ICD-10 Finland

Delayed and secondary postpartum haemorrhage

3.9

96.7

419

1099

SPAT1317

SPAT

Planned health check-up monitoring, health check-up performed based on individual need

1.8

95.0

1768

10352

MA2XE

NOMESCO Finland

Other obstetric ultrasound examination

2.1

94.2

1237

6350

65000

ICD-8 Finland

Delivery without mention of complication, Occipital presentation

1.6

93.4

3197

22390

Z34.9

ICD-10 Finland

Supervision of normal pregnancy, unspecified

1.8

93.2

1949

11853

MAX99

NOMESCO Finland

Assistance to normal delivery

1.8

91.8

1768

10459

O80.0

ICD-10 Finland

Spontaneous vertex delivery

1.5

90.7

4241

31967

67100

ICD-8 Finland

Puerperal phlebitis and thrombosis, Thrombophlebitis extremitatis inferioris

+∞

88.6

R10.3

ICD-10 Finland

Pain localized to other parts of lower abdomen

1.6

88.2

3162

22331

6749X

ICD-9 Finland

Other and unspecified complications of the puerperium, not elsewhere classified, Unspecified

+∞

83.4

R10.4

ICD-10 Finland

Other and unspecified abdominal pain

1.5

82.7

4146

31543

O92.4

ICD-10 Finland

Hypogalactia

400.5

80.0

N71.0

ICD-10 Finland

Acute inflammatory disease of uterus

2.7

78.8

587

2270

ZXE00

NOMESCO Finland

One hour or less

1.5

75.1

4254

33003

TMA00

NOMESCO Finland

Episiotomy

2.4

74.0

667

2867

LC2AE

NOMESCO Finland

Ultrasound examination of uterus and parametria

1.7

73.1

1807

11464

O92.1

ICD-10 Finland

Cracked nipple associated with childbirth

55.7

69.9

O82.0

ICD-10 Finland

Delivery by elective caesarean section

2.1

69.6

819

3991

W85

ICPC

Gestational diabetes

2.2

69.4

774

3682

N61

ICD-10 Finland

Inflammatory disorders of breast

2.6

66.8

511

2005

67003

ICD-8 Finland

+∞

66.7

O68.0

ICD-10 Finland

Labour and delivery complicated by fetal heart rate anomaly

2.0

65.8

876

4491

Z34

ICD-10 Finland

Supervision of normal pregnancy

2.0

64.5

865

4447

MA3AE

NOMESCO Finland

Combined first trimester screening

2.0

64.4

849

4333

MBA04

NOMESCO Finland

Curettage of uterus after delivery

5.5

64.3

196

359

W84

ICPC

Pregnancy high risk

2.2

63.7

683

3187

MA5AE

NOMESCO Finland

Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation

2.0

62.8

858

4443

O81.4

ICD-10 Finland

Vacuum extractor delivery

1.9

60.6

1023

5725

6743A

ICD-9 Finland

Other and unspecified complications of the puerperium, not elsewhere classified, Other complications of obstetrical surgical wounds

+∞

59.4

Z39.1

ICD-10 Finland

Care and examination of lactating mother

2.7

57.0

419

1606

8841

FHL

Uterine emptying and scraping (ad 6 weeks)

8.2

55.7

127

156

J01DA01

ATC

[U] cefalexin; systemic

1.4

54.9

6596

57354

WX602

NOMESCO Finland

Repeated or continuing anesthesia shots throug a catheter

1.7

54.3

1264

7823

O90.5

ICD-10 Finland

Postpartum thyroiditis

277.7

54.2

O20.9

ICD-10 Finland

Haemorrhage in early pregnancy, unspecified

2.3

52.9

522

2340

O73.1

ICD-10 Finland

Retained portions of placenta and membranes, without haemorrhage

4.6

51.6

184

402

WX306

NOMESCO Finland

Lumbar epidural anesthesy

1.7

47.9

1065

6490

J06.9

ICD-10 Finland

Acute upper respiratory infection, unspecified

1.3

47.9

5343

45423

W92

ICPC

Compl labour/ delivery livebirth

2.4

47.5

410

1717

MAE00

NOMESCO Finland

Outlet vacuum delivery

1.8

47.3

852

4860

6759X

ICD-9 Finland

Infections of the breast and nipple associated with childbirth, Unspecified infection of the breast and nipple

+∞

46.9

R3110

NOMESCO Finland

Psychosocial training

2.8

46.5

307

1102

XMA22

NOMESCO Finland

General examination of pregnant woman

1.8

46.5

936

5528

SPAT1399

SPAT

Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.

1.9

46.5

721

3904

O99.89

ICD-10 Finland

Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium

2.5

46.4

379

1542

O87.0

ICD-10 Finland

Superficial thrombophlebitis in the puerperium

74.8

45.9

O80.8

ICD-10 Finland

Other single spontaneous delivery

1.9

45.3

750

4156

O32.1

ICD-10 Finland

Maternal care for breech presentation

1.9

45.3

706

3830

WX321

NOMESCO Finland

Acute spinal anesthesia for delivery

1.9

44.8

704

3828

J01.0

ICD-10 Finland

Acute maxillary sinusitis

1.4

43.9

2770

21371

SPAT1196

SPAT

Monitoring of normal pregnancy

1.6

43.8

1194

7690

WX320

NOMESCO Finland

Spinalanesthesy

1.5

43.6

2017

14667

N02BE01

ATC

paracetamol; systemic, rectal

1.4

43.5

8942

83000

W29

ICPC

Pregnancy symptom/complaint other

2.2

43.4

470

2199

O36.6

ICD-10 Finland

Maternal care for excessive fetal growth

2.0

43.4

587

3016

O72.0

ICD-10 Finland

Third-stage haemorrhage

2.4

42.2

385

1659

O99.3

ICD-10 Finland

Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium

2.5

41.4

343

1405

MAC01

NOMESCO Finland

Rupture of aminiotic membrane for induction of labor

2.5

41.2

340

1392

MAC10

NOMESCO Finland

Antepartum dilatation of cervical canal

2.2

40.0

421

1943

Z32.0

ICD-10 Finland

Pregnancy, not (yet) confirmed

2.2

40.0

443

2095

O26.88

ICD-10 Finland

Other specified pregnancy-related conditions

2.7

39.8

279

1040

Z35.9

ICD-10 Finland

Supervision of high-risk pregnancy, unspecified

2.0

39.5

541

2792

W90

ICPC

Uncompl labour/delivery livebirth

1.8

39.1

772

4527

O13

ICD-10 Finland

Gestational [pregnancy-induced] hypertension

1.8

38.8

713

4086

ZXD10

NOMESCO Finland

Scheduled procedure

1.3

38.5

3552

29010

O26.82

ICD-10 Finland

Exhaustion and fatigue pregnancy-related

2.3

38.5

357

1552

Z35.2

ICD-10 Finland

Supervision of pregnancy with other poor reproductive or obstetric history

2.4

37.8

341

1463

O20.0

ICD-10 Finland

Threatened abortion

2.2

37.4

417

1976

O21.9

ICD-10 Finland

Vomiting of pregnancy, unspecified

2.7

36.6

265

1009

6712B

ICD-9 Finland

Venous complications in pregnancy and the puerperium, Superficial thrombophlebitis[THROMBOPHLEB SUPERFIC EXTR INF,PUERP AIKANA]

+∞

36.5

MBC30

NOMESCO Finland

Repair of partial rupture of perineum

2.4

35.8

325

1398

Z30.2

ICD-10 Finland

Sterilization

1.5

34.0

1347

9439

O91.0

ICD-10 Finland

Infection of nipple associated with childbirth

42.1

34.0

Z39.0

ICD-10 Finland

Care and examination immediately after delivery

2.9

33.8

215

758

LX1AE

NOMESCO Finland

Gynecological ultrasound examination as part of clinical examination

1.4

33.7

1585

11505

O99.2

ICD-10 Finland

Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium

2.4

33.5

297

1264

SPAT1246

SPAT

Screening of depression or other psychiatric problem

1.8

33.5

663

3886

WX322

NOMESCO Finland

Combined spinal-epidural analgesia in obstetrics

2.3

33.4

321

1421

M54.5

ICD-10 Finland

Low back pain

1.3

32.8

3268

26830

R51.80

ICD-10 Finland

Headache

1.4

32.6

1638

12029

Z36.0

ICD-10 Finland

Antenatal screening for chromosomal anomalies

1.7

32.6

795

4954

O63.1

ICD-10 Finland

Prolonged second stage (of labour)

1.9

31.9

462

2435

J01FF01

ATC

clindamycin; systemic

1.3

31.6

2426

19146

O47.9

ICD-10 Finland

False labour, unspecified

2.4

31.6

287

1238

O70.1

ICD-10 Finland

Second degree perineal laceration during delivery

2.0

31.3

413

2100

T81.4

ICD-10 Finland

Infection following a procedure, not elsewhere classified

1.6

31.1

935

6145

O92.2

ICD-10 Finland

Other and unspecified disorders of breast associated with childbirth

46.4

30.5

R74

ICPC

Upper respiratory infection acute

1.3

30.4

3535

29567

O02.1

ICD-10 Finland

Missed abortion

1.6

30.4

793

5030

G02AB01

ATC

methylergometrine; systemic

4.5

30.3

110

248

O92.5

ICD-10 Finland

Suppressed lactation

+∞

30.2

O72.1

ICD-10 Finland

Other immediate postpartum haemorrhage

2.0

30.0

388

1957

M79.6

ICD-10 Finland

Pain in limb

1.3

29.9

3362

27982

TAB22

NOMESCO Finland

Stoppin epidural fluid escape with coagulated blood

2.6

29.9

219

840

O46.9

ICD-10 Finland

Antepartum haemorrhage, unspecified

2.3

29.7

292

1307

W05

ICPC

Pregnancy vomiting/nausea

3.0

29.4

177

602

6742A

ICD-9 Finland

Other and unspecified complications of the puerperium, not elsewhere classified, Disruption of perineal wound

+∞

29.2

O63.0

ICD-10 Finland

Prolonged first stage (of labour)

2.1

29.0

347

1695

Z63.7

ICD-10 Finland

Other stressful life events affecting family and household

2.6

28.2

213

832

6751A

ICD-9 Finland

Infections of the breast and nipple associated with childbirth, Abscess of breast

+∞

28.1

MBA03

NOMESCO Finland

Curettage of uterus after delivery or abortion

1.9

28.1

431

2319

J01CA08

ATC

pivmecillinam; oral

1.3

28.1

5292

46820

SPAT1195

SPAT

Antenatal classes

1.8

27.8

502

2858

R21

ICPC

Throat symptom/complaint

1.3

27.7

2422

19426

O64.0

ICD-10 Finland

Obstructed labour due to incomplete rotation of fetal head

2.1

27.4

324

1578

MWC00

NOMESCO Finland

Reoperation for deep infection in obstetric surgery

47.2

27.4

W94

ICPC

Puerperal mastitis

3.3

27.2

142

439

SPAT1249

SPAT

Treatment-related counselling outside office

1.3

27.1

4036

34681

N76.0

ICD-10 Finland

Acute vaginitis

1.5

26.9

877

5870

O35.8

ICD-10 Finland

Maternal care for other (suspected) fetal abnormality and damage

2.1

26.7

300

1432

WYA05

NOMESCO Finland

Emergency visit or other similar visit involving procedures

1.2

26.6

5063

44726

J20.9

ICD-10 Finland

Acute bronchitis, unspecified

1.4

26.5

1532

11503

Z87.5

ICD-10 Finland

Personal history of complications of pregnancy, childbirth and the puerperium

2.8

26.2

172

618

MAC96

NOMESCO Finland

Other induction or advancement of labour

1.9

26.1

393

2102

SAA01

NOMESCO Finland

Simple examination of mouth

1.3

25.9

7678

71218

O87.1

ICD-10 Finland

Deep phlebothrombosis in the puerperium

93.6

25.6

MAC40

NOMESCO Finland

Pharmacological induction or advancement of labor

2.1

25.6

294

1413

SPAT1200

SPAT

Guidance for breast-feeding and breast care

1.8

25.4

441

2477

J02AC01

ATC

fluconazole; systemic

1.2

25.3

5268

46909

SPAT1357

SPAT

Monitoring of problem during pregnancy

1.8

25.2

439

2469

B01AB05

ATC

enoxaparin; parenteral

1.3

25.0

2350

18995

6703A

ICD-9 Finland

Major puerperal infection[SEPTICHAEMIA IN PUERPERIO]

+∞

25.0

A02BC01

ATC

omeprazole; systemic

1.3

24.9

2286

18416

Z2221

NOMESCO Finland

Medical doctor

1.3

24.9

2753

22740

EB1AA

NOMESCO Finland

Tooth X-ray examination

1.2

24.9

5669

50930

O60

ICD-10 Finland

Preterm labour and delivery

1.9

24.8

378

2031

WX110

NOMESCO Finland

Local anesthesy

1.2

24.8

7217

66589

Z32

ICD-10 Finland

Pregnancy examination and test

2.8

24.8

161

578

K02.1

ICD-10 Finland

Caries of dentine

1.2

24.2

6004

54351

W18

ICPC

Post-partum symptom/complaint other

3.5

24.1

115

333

O99.0

ICD-10 Finland

Anaemia complicating pregnancy, childbirth and the puerperium

2.6

23.7

174

670

O92.0

ICD-10 Finland

Retracted nipple associated with childbirth

13.3

23.6

SFA20

NOMESCO Finland

Filling on two surfaces of tooth

1.2

23.2

6078

55222

Z35.0

ICD-10 Finland

Supervision of pregnancy with history of infertility

1.8

23.2

423

2415

Z35

ICD-10 Finland

Supervision of high-risk pregnancy

2.6

23.2

172

669

Z03.9

ICD-10 Finland

Observation for suspected disease or condition, unspecified

1.4

23.1

1481

11291

O92.6

ICD-10 Finland

Galactorrhoea

8.0

23.0

R10.1

ICD-10 Finland

Pain localized to upper abdomen

1.3

23.0

1570

12091

R07.4

ICD-10 Finland

Chest pain, unspecified

1.3

22.9

1794

14109

R2110

NOMESCO Finland

Giving the first information

1.5

22.6

799

5441

MAA00

NOMESCO Finland

Amniocentesis

1.9

22.6

336

1789

A02BC02

ATC

pantoprazole; systemic

1.2

22.6

5949

54013

O03.9

ICD-10 Finland

Spontaneous abortion, Complete or unspecified, without complication

1.6

22.4

594

3778

N02AX02

ATC

tramadol; systemic, rectal

1.2

22.3

3314

28294

ZXE10

NOMESCO Finland

More than one and less than three hours

1.2

22.0

3090

26203

B02AA02

ATC

tranexamic acid; systemic

1.3

21.9

1875

14925

67101

ICD-8 Finland

Puerperal phlebitis and thrombosis, Thrombosis extremitatis inferioris

+∞

21.9

MBA30

NOMESCO Finland

Manual removal of placenta from delivered uterus

2.1

21.3

249

1210

E66.01

ICD-10 Finland

Obesity due to excess calories

1.5

21.3

885

6233

SPAT1283

SPAT

Restricted health certificate

1.3

21.3

2337

19219

MBA00

NOMESCO Finland

Vacuum aspiration from uterus after delivery or abortion

1.9

21.3

311

1647

O99.5

ICD-10 Finland

Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium

2.8

21.3

135

479

MBA96

NOMESCO Finland

Other removal of retained products of conception after delivery or abortion

2.0

21.1

289

1494

A09

ICD-10 Finland

Other gastroenteritis and colitis of infectious and unspecified origin

1.3

21.1

1494

11555

6758X

ICD-9 Finland

Infections of the breast and nipple associated with childbirth, Other specified infections of the breast and nipple

+∞

20.8

67808

ICD-8 Finland

Mastitis and other disorders of lactation, Alia definitae

+∞

20.8

O21.0

ICD-10 Finland

Mild hyperemesis gravidarum

2.5

20.8

163

652

O26.7

ICD-10 Finland

Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium

2.4

20.7

173

719

WX290

NOMESCO Finland

Other blockade of nerve

1.2

20.6

4844

43297

J01CE02

ATC

phenoxymethylpenicillin; oral

1.2

20.6

7337

68340

M54.4

ICD-10 Finland

Lumbago with sciatica

1.3

20.5

1497

11628

SAA02

NOMESCO Finland

Basic examination of mouth

1.2

20.2

7025

65199

G01AA10

ATC

clindamycin; vaginal

1.3

20.2

2051

16685

O35.1

ICD-10 Finland

Maternal care for (suspected) chromosomal abnormality in fetus

1.9

20.1

297

1579

R42

ICD-10 Finland

Dizziness and giddiness

1.3

20.0

1575

12367

O47

ICD-10 Finland

False labour

2.6

19.9

151

595

67002

ICD-8 Finland

Sepsis of childbirth and the puerperium, Salpingo-oophoritis

+∞

19.8

6718B

ICD-9 Finland

Venous complications in pregnancy and the puerperium, Other venous complications[HAEMORRHOIDES ANI,PUERP AIKANA]

+∞

19.8

O64.1

ICD-10 Finland

Obstructed labour due to breech presentation

2.1

19.6

221

1058

O82.11

ICD-10 Finland

Childbirth with an emergency caesarean section in an emergency

2.4

19.5

165

690

R03AC02

ATC

salbutamol; inhalant

1.2

19.4

5364

48596

8811

FHL

Cesarean section

1.5

19.3

679

4616

M01AE01

ATC

ibuprofen; systemic, rectal

1.3

19.2

9846

95118

UJD10

NOMESCO Finland

Esophagoscopy, gastroscopy and duodenoscopy

1.3

19.1

2134

17553

SPAT1263

SPAT

Sampling

1.2

19.0

4040

35662

SPAT1189

SPAT

Other ultrasound examination during pregnancy

1.6

19.0

473

2962

SFC01

NOMESCO Finland

Adjuvant procedure of filling therapy

1.3

18.9

2394

19995

SFA10

NOMESCO Finland

Fillning on one surface of tooth

1.2

18.9

5422

49243

M01AB05

ATC

diclofenac; systemic, rectal

1.2

18.8

6541

60474

Z71.8

ICD-10 Finland

Other specified counselling

1.3

18.7

2353

19627

N92.0

ICD-10 Finland

Excessive and frequent menstruation with regular cycle

1.3

18.5

1272

9784

J01AA02

ATC

doxycycline; systemic

1.2

18.5

7754

72921

MAW96

NOMESCO Finland

Other operation in pregnancy or at delivery

2.8

18.4

120

435

O36.9

ICD-10 Finland

Maternal care for fetal problem, unspecified

2.5

18.3

148

606

H02AB06

ATC

prednisolone; systemic

1.2

18.3

4089

36224

O61.0

ICD-10 Finland

Failed medical induction of labour

2.3

18.3

163

702

SPAT1223

SPAT

Implementation of physical therapy rehabilitation plan

1.2

18.1

2331

19490

Z30.1

ICD-10 Finland

Insertion of (intrauterine) contraceptive device

1.3

17.9

1730

13960

G43.9

ICD-10 Finland

Migraine, unspecified

1.4

17.9

745

5250

G02CB01

ATC

bromocriptine; systemic

1.9

17.9

255

1344

M01AE02

ATC

naproxen; oral, rectal

1.2

17.8

5813

53280

WX000

NOMESCO Finland

Monitoring vital functions without anesthesy

1.7

17.8

338

1960

M03BX02

ATC

tizanidine; oral

1.2

17.6

6487

60086

WZB00

NOMESCO Finland

Telephone receipt or other advice

1.2

17.5

2950

25376

OAA11

SPAT

1.7

17.4

385

2335

O87.2

ICD-10 Finland

Haemorrhoids in the puerperium

10.7

17.4

N81.1

ICD-10 Finland

Cystocele

1.5

17.2

567

3799

O48

ICD-10 Finland

Prolonged pregnancy

1.6

17.2

453

2881

O21

ICD-10 Finland

Excessive vomiting in pregnancy

2.6

17.2

126

488

OAA12

SPAT

2.0

17.0

231

1192

J01CR02

ATC

amoxicillin and beta-lactamase inhibitor; systemic

1.2

17.0

5118

46496

J01CA04

ATC

amoxicillin; systemic

1.2

16.9

8710

83121

R06.0

ICD-10 Finland

Dyspnoea

1.3

16.8

1756

14307

W19

ICPC

Lactation symptom/complaint

3.0

16.7

326

ZXD00

NOMESCO Finland

Emergency procedure

1.8

16.6

287

1613

N02AA59

ATC

codeine, combinations excl. psycholeptics; systemic

1.2

16.6

4216

37691

O75.0

ICD-10 Finland

Maternal distress during labour and delivery

2.2

16.5

167

765

R05

ICPC

Cough

1.2

16.4

2047

17024

O26.6

ICD-10 Finland

Liver disorders in pregnancy, childbirth and the puerperium

2.0

16.4

218

1120

N02CC01

ATC

sumatriptan; nasal, systemic, rectal

1.3

16.4

1778

14542

N92.6

ICD-10 Finland

Irregular menstruation, unspecified

1.4

16.3

827

6047

N02AJ06

ATC

codeine and paracetamol; systemic

1.2

16.2

3302

28903

LGA10

NOMESCO Finland

Sterilisation by destruction or division of Fallopian tubes

2.4

16.2

134

556

SPAT1315

SPAT

Periodic health check-up of children and adolescents

1.6

16.2

433

2764

M54.9

ICD-10 Finland

Dorsalgia, unspecified

1.4

16.2

974

7330

L03

ICPC

Low back symptom/complaint

1.2

16.2

2229

18742

O47.1

ICD-10 Finland

False labour at or after 37 completed weeks of gestation

1.5

16.1

488

3206

O99.1

ICD-10 Finland

Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium

2.6

16.1

118

460

SPAT1310

SPAT

Counselling related to known health issue

1.2

16.1

2827

24385

MBC10

NOMESCO Finland

Repair of obstetric laceration of vagina

1.9

16.1

250

1359

O10.0

ICD-10 Finland

Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium

1.9

16.0

227

1195

SPAT1240

SPAT

Therapeutic discussion

1.3

15.9

1197

9321

Z36.8

ICD-10 Finland

Other antenatal screening

1.8

15.9

290

1665

MWE00

NOMESCO Finland

Reoperation for deep haemorrhage in obstetric surgery

5.5

15.8

O36.8

ICD-10 Finland

Maternal care for other specified fetal problems

1.9

15.7

227

1204

G44.2

ICD-10 Finland

Tension-type headache

1.3

15.7

1367

10868

6714A

ICD-9 Finland

Venous complications in pregnancy and the puerperium, Deep phlebothrombosis, postpartum[THROMBOPHLEB PROF EXTR INFER,RASKAUDEN AIKANA]

+∞

15.6

6764A

ICD-9 Finland

Other disorders of the breast associated with childbirth, and disorders of lactation, Failure of lactation

+∞

15.6

6715A

ICD-9 Finland

Venous complications in pregnancy and the puerperium, Other phlebitis and thrombosis[PHLEBITIS/THROMBOSIS ALIA,RASKAUDEN AIKANA]

+∞

15.6

O30.0

ICD-10 Finland

Twin pregnancy

1.9

15.6

222

1169

R51

ICD-10 Finland

Headache

1.5

15.5

523

3528

A03

ICPC

Fever

1.3

15.5

1612

13112

65220

ICD-8 Finland

Occipital presentation

4.7

15.4

112

SGC00

NOMESCO Finland

Local medication of root channels of tooth

1.3

15.4

1019

7782

G43.0

ICD-10 Finland

Migraine without aura [common migraine]

1.4

15.4

706

5069

Z87.1

ICD-10 Finland

Personal history of diseases of the digestive system

1.2

15.3

4174

37460

UJF32

NOMESCO Finland

Coloscopy

1.3

14.9

1766

14578

U07.1

ICD-10 Finland

Emergency use of U07.1 | COVID-19, virus identified

1.2

14.8

1933

16139

PH2AE

NOMESCO Finland

Ultrasound examination of lower leg veins

1.4

14.8

757

5541

6660C

ICD-9 Finland

Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM CUM RETENT PLAC PARTIALI]

3.5

14.8

200

O14.0

ICD-10 Finland

Mild to moderate pre-eclampsia

1.8

14.7

234

1283

J45.9

ICD-10 Finland

Asthma, unspecified

1.3

14.6

1433

11558

O20.8

ICD-10 Finland

Other haemorrhage in early pregnancy

2.7

14.6

352

6712A

ICD-9 Finland

Venous complications in pregnancy and the puerperium, Superficial thrombophlebitis[THROMBOPHLEB SUPERFIC EXTR INF,RASKAUDEN AIKANA]

+∞

14.6

K08.80

ICD-10 Finland

Toothache NOS

1.4

14.5

801

5940

N01

ICPC

Headache

1.3

14.5

1039

8031

N83.2

ICD-10 Finland

Other and unspecified ovarian cysts

1.3

14.4

1257

9983

N05BA04

ATC

oxazepam; oral

1.2

14.4

2239

19046

D82

ICPC

Teeth/gum disease

1.2

14.3

3559

31636

8221

FHL

Sterilization of the laparotomy pathway

1.6

14.2

335

2071

V252A

ICD-9 Finland

Contraceptive management, Sterilisation

1.4

14.1

879

6646

WZC00

NOMESCO Finland

Planning of intervention or health care consultation

1.2

14.1

2955

25856

J01DA09

ATC

[U] cefadroxil; inhalant, oral

1.2

14.1

2551

22018

WX408

NOMESCO Finland

General anesthesy, balanced

1.2

14.1

2133

18083

O03.4

ICD-10 Finland

Spontaneous abortion, Incomplete, without complication

1.7

14.1

289

1719

J01FA06

ATC

roxithromycin; oral

1.2

14.1

3798

33984

66100

ICD-8 Finland

Occipital presentation

2.4

14.1

114

470

R53

ICD-10 Finland

Malaise and fatigue

1.2

14.1

1674

13821

S18

ICPC

Laceration/cut

1.2

14.0

3110

27354

SPAT1312

SPAT

General health counselling

1.2

14.0

3001

26311

SPAT1391

SPAT

Counselling and guidance related to family situation

2.1

13.9

164

806

WX600

NOMESCO Finland

Single shot through catheter

1.8

13.9

235

1319

O99.4

ICD-10 Finland

Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium

2.7

13.8

350

N39.0

ICD-10 Finland

Urinary tract infection, site not specified

1.3

13.8

1066

8332

O36.5

ICD-10 Finland

Maternal care for poor fetal growth

1.6

13.7

361

2298

N81.6

ICD-10 Finland

Rectocele

1.4

13.6

588

4173

EB1SA

NOMESCO Finland

Dental X-ray, bite-wing X-ray on one side of the mouth

1.2

13.5

5716

52979

FM1EE

NOMESCO Finland

Extensive structural and functional ultrasound examination of heart

1.3

13.4

1090

8572

M25.5

ICD-10 Finland

Pain in joint

1.2

13.4

2715

23660

XLA10

NOMESCO Finland

1.4

13.4

576

4085

SFA30

NOMESCO Finland

Filling on tree or more surfaces of tooth

1.2

13.3

3618

32350

O26.9

ICD-10 Finland

Pregnancy-related condition, unspecified

2.7

13.3

340

SPAT1230

SPAT

Aid fitting and borrowing and monitoring of use

1.3

13.3

1115

8806

M01AE03

ATC

ketoprofen; systemic, rectal

1.2

13.3

3014

26536

SPAT1307

SPAT

Psychosocial counselling and guidance

1.4

13.2

682

5001

J03.9

ICD-10 Finland

Acute tonsillitis, unspecified

1.4

13.1

538

3781

R11

ICD-10 Finland

Nausea and vomiting

1.4

13.1

631

4573

I87.2

ICD-10 Finland

Venous insufficiency (chronic)(peripheral)

1.4

13.1

742

5528

GD1AA

NOMESCO Finland

Thorax X-ray examination

1.2

13.1

2843

24932

MBC40

NOMESCO Finland

Revision of paravaginal or vulvar haematoma after delivery or abortion

4.8

13.0

O32.2

ICD-10 Finland

Maternal care for transverse and oblique lie

2.5

13.0

104

426

O73.0

ICD-10 Finland

Retained placenta without haemorrhage

2.3

12.9

122

545

SPAT1306

SPAT

Counselling and guidance related to nutrition and weight management

1.3

12.9

1058

8330

K10.3

ICD-10 Finland

Alveolitis of jaws

1.5

12.9

433

2920

M53.1

ICD-10 Finland

Cervicobrachial syndrome

1.3

12.8

1057

8334

I49.9

ICD-10 Finland

Cardiac arrhythmia, unspecified

1.3

12.7

906

6992

K04.0

ICD-10 Finland

Pulpitis

1.3

12.7

942

7313

O03.1

ICD-10 Finland

Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage

1.8

12.7

208

1157

O44.0

ICD-10 Finland

Placenta praevia specified as without haemorrhage

2.3

12.6

119

530

O14.9

ICD-10 Finland

Pre-eclampsia, unspecified

1.9

12.6

177

934

D06

ICPC

Abdominal pain localized other

1.4

12.5

752

5654

M79.1

ICD-10 Finland

Myalgia

1.3

12.5

1189

9544

67099

ICD-8 Finland

+∞

12.5

O42.0

ICD-10 Finland

Premature rupture of membranes, onset of labour within 24 hours

1.7

12.5

233

1348

O42.1

ICD-10 Finland

Premature rupture of membranes, onset of labour after 24 hours

1.9

12.4

174

917

N71.9

ICD-10 Finland

Inflammatory disease of uterus, unspecified

2.4

12.4

104

439

Z39

ICD-10 Finland

Postpartum care and examination

2.0

12.4

163

838

R07.0

ICD-10 Finland

Pain in throat

1.4

12.4

579

4175

TMW99

NOMESCO Finland

Other minor surgical procedure in obstetrics

2.2

12.3

125

578

J01FA01

ATC

erythromycin; systemic

1.2

12.3

1553

12894

R50.9

ICD-10 Finland

Fever, unspecified

1.3

12.2

995

7827

Z04.8

ICD-10 Finland

Examination and observation for other specified reasons

1.3

12.2

1026

8106

MBA05

NOMESCO Finland

Curettage of uterus after abortion

2.0

12.2

144

710

WX404

NOMESCO Finland

Intravenous generell anesthesy

1.2

12.2

1876

15901

A02BC05

ATC

esomeprazole; systemic

1.2

12.2

3493

31318

J01FA10

ATC

azithromycin; systemic

1.2

12.1

6327

59340

O75.7

ICD-10 Finland

Vaginal delivery following previous caesarean section

3.4

12.1

168

N06AB04

ATC

citalopram; systemic

1.2

12.0

1968

16791

O91

ICD-10 Finland

Infections of breast associated with childbirth

6.2

11.9

R00.2

ICD-10 Finland

Palpitations

1.4

11.9

646

4780

LGA20

NOMESCO Finland

Sterilisation by constriction of Fallopian tubes

2.1

11.7

131

632

J20

ICD-10 Finland

Acute bronchitis

1.3

11.7

774

5909

WYA40

NOMESCO Finland

Assessment of oral health and treatment needs for family expecting first child

1.7

11.7

242

1449

A10BA02

ATC

metformin; oral

1.2

11.7

1421

11749

Z09.0

ICD-10 Finland

Follow-up examination after surgery for other conditions

1.3

11.6

792

6073

MBA40

NOMESCO Finland

Pharmacological evacuation of uterus after abortion

1.8

11.6

204

1162

Z01.2

ICD-10 Finland

Dental examination

1.2

11.5

4152

37831

ULC02

NOMESCO Finland

Hysteroscopy

1.4

11.5

569

4142

Y6099

ICD-8 Finland

Prenatal care and observation

1.5

11.5

441

3062

SPAT1281

SPAT

Other administrative function

1.4

11.5

605

4454

6718A

ICD-9 Finland

Venous complications in pregnancy and the puerperium, Other venous complications[HAEMORRHOIDES ANI,RASKAUDEN AIKANA]

+∞

11.5

N30.0

ICD-10 Finland

Acute cystitis

1.3

11.4

1259

10285

Z12

ICPC

Relationship problem with partner

1.8

11.4

200

1138

N81.2

ICD-10 Finland

Incomplete uterovaginal prolapse

1.5

11.3

417

2870

8502

FHL

Evacuation and abrasion

1.4

11.3

474

3351

W27

ICPC

Fear of complications of pregnancy

2.0

11.3

143

725

G01AF05

ATC

econazole; vaginal

1.3

11.1

938

7411

D01

ICPC

Abdominal pain/cramps general

1.3

11.1

966

7662

EB1HA

NOMESCO Finland

Panorama tomography of teeth and jaws or similar X-ray examination

1.2

11.1

3746

33941

MWW96

NOMESCO Finland

Other reoperation in obstetric surgery

12.7

11.1

SPAT1238

SPAT

Brief therapy

1.7

11.0

215

1264

G43.1

ICD-10 Finland

Migraine with aura [classical migraine]

1.3

11.0

756

5802

O42.9

ICD-10 Finland

Premature rupture of membranes, unspecified

1.5

11.0

429

2989

R01AD12

ATC

fluticasone furoate; nasal

1.2

11.0

3254

29187

SPAT1192

SPAT

Gynaecological examination

1.2

11.0

1390

11535

64399

ICD-8 Finland

Spontaneous abortion, Without mention of sepsis or toxaemia

1.5

11.0

336

2224

R10.2

ICD-10 Finland

Pelvic and perineal pain

1.7

11.0

200

1154

SPAT1375

SPAT

Structural ultrasound screening, weeks 18+0-21+6

1.9

10.9

165

897

MAC02

NOMESCO Finland

Rupture of aminiotic membrane for advancement of labor

2.5

10.8

316

H66.0

ICD-10 Finland

Acute suppurative otitis media

1.4

10.8

569

4193

C05AA08

ATC

fluocortolone; rectal, topical

1.3

10.7

1065

8592

63703

ICD-8 Finland

Pre-eclampsia, eclampsia and toxaemia, unspecified, Prae-eclampsia levis

1.9

10.7

147

768

N83.1

ICD-10 Finland

Corpus luteum cyst

1.8

10.7

173

959

O02.0

ICD-10 Finland

Blighted ovum and nonhydatidiform mole

1.5

10.7

383

2622

63230

ICD-8 Finland

Haemorrhage of pregnancy, Threatened abortion

1.7

10.7

237

1444

TQW30

NOMESCO Finland

Acupuncture

2.3

10.6

396

SGA01

NOMESCO Finland

Tooth opening as first aid

1.2

10.6

1488

12481

TEW99

NOMESCO Finland

Other minor procedure in surgery of teeth, jaws, mouth and pharynx

1.5

10.6

372

2537

K42.9

ICD-10 Finland

Umbilical hernia without obstruction or gangrene

1.6

10.6

251

1558

JKA21

NOMESCO Finland

Laparoscopic cholecystectomy

1.3

10.6

937

7451

Z01.4

ICD-10 Finland

Gynaecological examination (general)(routine)

1.2

10.5

2220

19363

N73.9

ICD-10 Finland

Female pelvic inflammatory disease, unspecified

1.7

10.5

213

1271

V230A

ICD-9 Finland

Supervision of high-risk pregnancy, Pregnancy with history of infertility

2.1

10.4

117

568

O41.0

ICD-10 Finland

Oligohydramnios

1.6

10.4

243

1504

67809

ICD-8 Finland

Mastitis and other disorders of lactation, Unspecified

+∞

10.4

67001

ICD-8 Finland

Sepsis of childbirth and the puerperium, Lymphangitis uteri

+∞

10.4

O87.3

ICD-10 Finland

Cerebral venous thrombosis in the puerperium

+∞

10.4

6714B

ICD-9 Finland

Venous complications in pregnancy and the puerperium, Deep phlebothrombosis, postpartum[THROMBOPHLEB PROF EXTR INFER,PUERP AIKANA]

+∞

10.4

67802

ICD-8 Finland

Mastitis and other disorders of lactation, Abscessus mammae

+∞

10.4

L02

ICPC

Back symptom/complaint

1.3

10.4

802

6265

D11

ICPC

Diarrhoea

1.3

10.3

1080

8768

O24.9

ICD-10 Finland

Diabetes mellitus in pregnancy, unspecified

1.7

10.3

218

1314

Z03.89

ICD-10 Finland

Observation for other suspected diseases and conditions

1.3

10.3

912

7255

O68.8

ICD-10 Finland

Labour and delivery complicated by other evidence of fetal stress

2.0

10.2

120

593

W12

ICPC

Contraception intrauterine

1.2

10.2

1311

10892

R01AD09

ATC

mometasone; nasal

1.1

10.2

4767

44119

O28.8

ICD-10 Finland

Other abnormal findings on antenatal screening of mother

1.9

10.2

143

756

SPAT1389

SPAT

Visit based on need for special support

1.6

10.1

235

1451

SAA03

NOMESCO Finland

Extended examination of mouth

1.1

10.1

3768

34321

J01MA02

ATC

ciprofloxacin; systemic

1.2

10.1

2827

25214

6500B

ICD-9 Finland

Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]

1.2

10.1

2053

17835

6440A

ICD-9 Finland

Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]

1.7

10.1

202

1198

M03BC51

ATC

orphenadrine, combinations; systemic

1.2

10.1

2699

23992

8831

FHL

Uterine exploration and / or scraping or suction emptying (ad 24 hours)

2.6

10.0

264

MAA40

NOMESCO Finland

Puncture of fetus

2.2

10.0

435

K43.9

ICD-10 Finland

Other and unspecified ventral hernia without obstruction or gangrene

1.6

10.0

266

1706

Z09.8

ICD-10 Finland

Follow-up examination after other treatment for other conditions

1.5

10.0

343

2330

M01AH05

ATC

etoricoxib; oral

1.1

9.9

5617

52614

N39.3

ICD-10 Finland

Stress incontinence

1.3

9.9

666

5099

K03.64

ICD-10 Finland

Dental calculus supragingival

1.2

9.9

2858

25553

J01FA09

ATC

clarithromycin; systemic

1.2

9.8

3060

27499

SPAT1325

SPAT

Vaccination

1.2

9.8

2404

21209

P03

ICPC

Feeling depressed

1.3

9.8

973

7850

M03BC01

ATC

orphenadrine (citrate); systemic

1.2

9.7

2307

20296

SPAT1373

SPAT

Combined screening in early pregnancy

1.6

9.7

239

1500

8842

FHL

Peritoneal and vaginal wound revision

9.5

9.7

S13.4

ICD-10 Finland

Sprain and strain of cervical spine

1.5

9.7

358

2468

S06.0

ICD-10 Finland

Concussion

1.3

9.7

723

5620

WX230

NOMESCO Finland

Plexus blockade of nervus pudendus

1.8

9.7

155

860

F32.10

ICD-10 Finland

Moderate depressive episode without somatic syndrome

1.3

9.7

841

6676

K80.2

ICD-10 Finland

Calculus of gallbladder without cholecystitis

1.3

9.5

955

7713

J01

ICD-10 Finland

Acute sinusitis

1.4

9.5

497

3654

O75.6

ICD-10 Finland

Delayed delivery after spontaneous or unspecified rupture of membranes

1.7

9.5

204

1237

67790

ICD-8 Finland

Other and unspecified complications of the puerperium, Retentio placentae partialis

3.3

9.5

135

I80.0

ICD-10 Finland

Phlebitis and thrombophlebitis of superficial vessels of lower extremities

1.6

9.5

259

1671

I83.9

ICD-10 Finland

Varicose veins of lower extremities without ulcer or inflammation

1.3

9.5

797

6297

J03

ICD-10 Finland

Acute tonsillitis

1.6

9.5

246

1570

SDA01

NOMESCO Finland

Simple parodonthologic therapy

1.2

9.4

2483

22021

N30.9

ICD-10 Finland

Cystitis, unspecified

1.4

9.4

436

3141

O03.0

ICD-10 Finland

Spontaneous abortion, Incomplete, complicated by genital tract and pelvic infection

2.2

9.4

409

LX1XE

NOMESCO Finland

Other gynecological ultrasound examination

1.5

9.4

310

2090

N92.1

ICD-10 Finland

Excessive and frequent menstruation with irregular cycle

1.3

9.4

709

5518

WX400

NOMESCO Finland

Inhalation anesthesy

1.4

9.4

389

2746

L28

ICPC

Limited function/disability (L)

1.3

9.4

837

6664

F32.9

ICD-10 Finland

Depressive episode, unspecified

1.2

9.4

1200

9969

Z00.4

ICD-10 Finland

General psychiatric examination, not elsewhere classified

1.3

9.4

911

7332

N93.9

ICD-10 Finland

Abnormal uterine and vaginal bleeding, unspecified

1.6

9.3

235

1488

T81.0

ICD-10 Finland

Haemorrhage and haematoma complicating a procedure, not elsewhere classified

1.4

9.2

448

3252

6671A

ICD-9 Finland

Retained placenta or membranes, without haemorrhage, Retained portions of placenta or membranes, without haemorrhage

2.7

9.2

223

LCA06

NOMESCO Finland

Biopsy of endometrium

1.2

9.2

1380

11645

J01.9

ICD-10 Finland

Acute sinusitis, unspecified

1.5

9.2

341

2358

J03.0

ICD-10 Finland

Streptococcal tonsillitis

1.5

9.2

292

1953

KMAK

NOMESCO Finland

1.1

9.1

5570

52302

J02.9

ICD-10 Finland

Acute pharyngitis, unspecified

1.4

9.1

452

3293

R06AE07

ATC

cetirizine; oral

1.1

9.1

4564

42328

O24.0

ICD-10 Finland

Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent

1.6

9.0

200

1224

O71.4

ICD-10 Finland

Obstetric high vaginal laceration

2.2

9.0

389

PHD99

NOMESCO Finland

Resection of other vein

1.4

9.0

514

3841

B37.3

ICD-10 Finland

Candidiasis of vulva and vagina

1.7

9.0

176

1042

O14.1

ICD-10 Finland

Severe pre-eclampsia

2.0

9.0

108

542

Z35.4

ICD-10 Finland

Supervision of pregnancy with grand multiparity

2.1

9.0

433

N06AB10

ATC

escitalopram; oral

1.2

8.9

2079

18247

O35.9

ICD-10 Finland

Maternal care for (suspected) fetal abnormality and damage, unspecified

1.9

8.9

127

679

PHD76

NOMESCO Finland

Resection of long saphenous vein

1.4

8.9

374

2646

R20.2

ICD-10 Finland

Paraesthesia of skin

1.3

8.9

570

4333

OAA10

SPAT

1.6

8.9

196

1200

O21.1

ICD-10 Finland

Hyperemesis gravidarum with metabolic disturbance

2.7

8.8

211

H10.0

ICD-10 Finland

Mucopurulent conjunctivitis

1.4

8.8

488

3631

65700

ICD-8 Finland

Occipital presentation

2.0

8.7

108

548

N06AX21

ATC

duloxetine; oral

1.2

8.7

954

7790

M54.2

ICD-10 Finland

Cervicalgia

1.3

8.6

570

4359

K21.9

ICD-10 Finland

Gastro-oesophageal reflux disease without oesophagitis

1.3

8.6

720

5688

H01

ICPC

Ear pain/earache

1.2

8.5

964

7898

W99

ICPC

Disorder of pregn/delivery other

2.6

8.5

228

Z37.2

ICD-10 Finland

Twins, both liveborn

2.9

8.5

175

Y83.8

ICD-10 Finland

Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

1.6

8.5

203

1271

N63

ICD-10 Finland

Unspecified lump in breast

1.3

8.5

647

5050

SDA03

NOMESCO Finland

Demanding parodonthologic therapy

1.1

8.4

3586

32858

N64.3

ICD-10 Finland

Galactorrhoea not associated with childbirth

2.4

8.4

284

J01EA01

ATC

trimethoprim; systemic

1.2

8.4

2498

22331

O22.3

ICD-10 Finland

Deep phlebothrombosis in pregnancy

3.7

8.4

H60.9

ICD-10 Finland

Otitis externa, unspecified

1.3

8.4

511

3860

N64.4

ICD-10 Finland

Mastodynia

1.5

8.4

297

2037

N03AX16

ATC

pregabalin; oral

1.2

8.4

1775

15459

M54

ICD-10 Finland

Dorsalgia

1.2

8.3

954

7825

6768X

ICD-9 Finland

Other disorders of the breast associated with childbirth, and disorders of lactation, Other disorders of lactation

+∞

8.3

SPAT1292

SPAT

Other function in accordance with SHToL (Finnish classification of nursing interventions)

1.4

8.3

476

3559

O41.1

ICD-10 Finland

Infection of amniotic sac and membranes

1.9

8.3

118

632

O99.6

ICD-10 Finland

Diseases of the digestive system complicating pregnancy, childbirth and the puerperium

1.9

8.3

111

578

O12.0

ICD-10 Finland

Gestational oedema

2.4

8.3

280

M23.9

ICD-10 Finland

Internal derangement of knee, unspecified

1.3

8.3

681

5368

MBC33

NOMESCO Finland

Repair of complete rupture of perineum

2.1

8.2

407

SPAT1153

SPAT

Removal of sutures

1.2

8.2

2275

20228

Z03.3

ICD-10 Finland

Observation for suspected nervous system disorder

1.4

8.1

383

2770

O36.4

ICD-10 Finland

Maternal care for intrauterine death

2.3

8.1

324

SDA04

NOMESCO Finland

Very demanding parodonthologic therapy

1.2

8.1

2147

19018

LGA00

NOMESCO Finland

Sterilisation by ligature of Fallopian tubes

2.4

8.1

286

JN1AE

NOMESCO Finland

Ultrasound examination of upper part of abdomen

1.3

8.1

616

4804

I49.4

ICD-10 Finland

Other and unspecified premature depolarization

1.5

8.0

239

1576

M53.0

ICD-10 Finland

Cervicocranial syndrome

1.3

8.0

766

6154

E66.8

ICD-10 Finland

Other obesity

1.3

8.0

494

3741

J01FA15

ATC

telithromycin; oral

1.2

8.0

856

6969

R03DC03

ATC

montelukast; oral

1.2

8.0

1489

12823

O70.21

ICD-10 Finland

III degree perineal tear involving less than one half of external anal sphincter thickness torn during childbirth

3.1

7.9

133

Z01.8

ICD-10 Finland

Other specified special examinations

1.2

7.9

1658

14415

SPAT1273

SPAT

Structured assessment of psychoactive substance / tobacco use

1.4

7.9

359

2580

SCA01

NOMESCO Finland

Simple analysis and advice of nutrition with regard to dentistry

1.1

7.9

2719

24544

Y83

ICD-10 Finland

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

1.3

7.9

472

3555

M02AA07

ATC

piroxicam; topical

1.1

7.9

2753

24876

A06AC01

ATC

ispaghula (psylla seeds); oral

1.2

7.8

1818

15938

WYA50

NOMESCO Finland

Student oral health check consistent with decree to assess need for oral health guidance and services

0.6

7.8

1660

F45.8

ICD-10 Finland

Other somatoform disorders

1.3

7.8

766

6172

K02

ICD-10 Finland

Dental caries

1.3

7.8

551

4254

H10.9

ICD-10 Finland

Conjunctivitis, unspecified

1.3

7.8

450

3374

6441A

ICD-9 Finland

Early or threatened labour, Other threatened labour

1.7

7.7

139

803

NE1AG

NOMESCO Finland

MRI pelvimetry with high intensity magnet

1.9

7.7

100

519

MAB10

NOMESCO Finland

External version

2.0

7.7

442

LC2HE

NOMESCO Finland

Hystero-salpingography with ultrasound

1.3

7.6

592

4631

G03DB01

ATC

dydrogesterone; oral

1.2

7.6

1759

15409

Z30.5

ICD-10 Finland

Surveillance of (intrauterine) contraceptive device

1.2

7.6

825

6725

TLW99

NOMESCO Finland

Other minor surgical procedure in gynaecology

1.6

7.6

196

1252

MA4AT

NOMESCO Finland

Chorion biopsy with ultrasound guidance

2.0

7.6

431

V220A

ICD-9 Finland

Normal pregnancy, Supervision of normal first pregnancy

1.6

7.6

192

1218

R03AK06

ATC

salmeterol and fluticasone; inhalant

1.2

7.6

955

7915

O23.1

ICD-10 Finland

Infections of bladder in pregnancy

2.6

7.6

207

R83

ICPC

Respiratory infection other

1.1

7.5

2701

24437

OAA41

SPAT

1.8

7.5

113

616

65710

ICD-8 Finland

Occipital presentation

1.7

7.5

157

950

E66.9

ICD-10 Finland

Obesity, unspecified

1.4

7.5

299

2099

ZXH09

SPAT

1.6

7.5

183

1152

O84.2

ICD-10 Finland

Multiple delivery, all by caesarean section

2.4

7.5

253

M51.1

ICD-10 Finland

Lumbar and other intervertebral disc disorders with radiculopathy

1.2

7.5

1031

8625

AA1AD

NOMESCO Finland

CT of head and brain

1.2

7.5

1263

10776

O65.4

ICD-10 Finland

Obstructed labour due to fetopelvic disproportion, unspecified

2.2

7.4

316

M54.3

ICD-10 Finland

Sciatica

1.4

7.4

413

3078

SPAT1392

SPAT

Counselling and guidance related to couple relationship

2.0

7.4

407

Z31.5

ICD-10 Finland

Genetic counselling

1.3

7.4

536

4153

O87.9

ICD-10 Finland

Venous complication in the puerperium, unspecified

80.1

7.4

F41.9

ICD-10 Finland

Anxiety disorder, unspecified

1.2

7.4

901

7442

MBC20

NOMESCO Finland

Repair of obstetric laceration of vulva

2.3

7.4

298

67798

ICD-8 Finland

Other and unspecified complications of the puerperium, Alia definita

3.5

7.3

O64.8

ICD-10 Finland

Obstructed labour due to other malposition and malpresentation

2.1

7.3

367

T78.4

ICD-10 Finland

Allergy, unspecified

1.3

7.3

432

3249

SDA02

NOMESCO Finland

Parodonthologic therapy

1.1

7.3

3118

28518

O92.3

ICD-10 Finland

Agalactia

+∞

7.3

O88.2

ICD-10 Finland

Obstetric blood-clot embolism

+∞

7.3

O90.3

ICD-10 Finland

Cardiomyopathy in the puerperium

+∞

7.3

6715B

ICD-9 Finland

Venous complications in pregnancy and the puerperium, Other phlebitis and thrombosis[PHLEBITIS/THROMBOSIS ALIA,PUERP AIKANA]

+∞

7.3

O00.9

ICD-10 Finland

Ectopic pregnancy, unspecified

1.8

7.3

126

720

N97.9

ICD-10 Finland

Female infertility, unspecified

1.3

7.3

696

5594

R60.0

ICD-10 Finland

Localized oedema

1.3

7.3

601

4744

WZA90

NOMESCO Finland

Other doctors statement

1.2

7.3

1971

17486

8113

FHL

Fractional scraping

1.4

7.2

382

2823

SPAT1260

SPAT

Consultation of another employee

1.2

7.2

1338

11508

Z29

ICPC

Social problem NOS

1.7

7.2

150

907

Z16

ICPC

Relationship problem with child

2.3

7.2

257

C08CA05

ATC

nifedipine; systemic

1.4

7.1

326

2349

MBW96

NOMESCO Finland

Other operation after delivery or abortion

3.2

7.1

105

JAF10

NOMESCO Finland

Repair of umbilical hernia

1.8

7.1

115

644

R01AD08

ATC

fluticasone; nasal

1.1

7.1

2777

25256

67699

ICD-8 Finland

Anaemia of the puerperium

2.4

7.1

233

X15

ICPC

Vaginal symptom/complaint other

1.4

7.1

387

2877

SGA02

NOMESCO Finland

Opening and dilatation of root canal of tooth

1.2

7.0

980

8209

O70.0

ICD-10 Finland

First degree perineal laceration during delivery

1.8

7.0

107

588

O30.00

ICD-10 Finland

Twin pregnancy with separate amniotic and chorionic sacs

2.3

7.0

274

J32.0

ICD-10 Finland

Chronic maxillary sinusitis

1.3

7.0

647

5177

B01AA03

ATC

warfarin; systemic

1.3

7.0

556

4366

JN3BD

NOMESCO Finland

Extensive abdominal CT

1.3

7.0

685

5525

O45.8

ICD-10 Finland

Other premature separation of placenta

3.7

6.9

K04.08

ICD-10 Finland

Other specified pulpit

1.3

6.9

581

4598

SGA04

NOMESCO Finland

Very demanding opening and dilatation of root canal of tooth

1.2

6.9

971

8141

O62.0

ICD-10 Finland

Primary inadequate contractions

2.1

6.9

322

G03GA01

ATC

chorionic gonadotrophin; parenteral

1.3

6.9

490

3789

LCH11

NOMESCO Finland

Pharmacologic abortion

1.3

6.9

518

4038

F33.10

ICD-10 Finland

Recurrent depression, moderate episode without somatic syndrome

1.3

6.9

574

4536

SGA03

NOMESCO Finland

Demanding opening and dilatation of root canal of tooth

1.2

6.9

806

6631

65210

ICD-8 Finland

Occipital presentation

2.2

6.9

279

X17

ICPC

Pelvis symptom/complaint female

1.8

6.8

113

638

K04.00

ICD-10 Finland

Hyperemia of pulp

1.4

6.8

385

2877

Z76.9

ICD-10 Finland

Person encountering health services in unspecified circumstances

1.3

6.8

527

4126

M75.1

ICD-10 Finland

Rotator cuff syndrome

1.2

6.8

1622

14244

H66.9

ICD-10 Finland

Otitis media, unspecified

1.3

6.8

466

3591

O86

ICD-10 Finland

Other puerperal infections

40.0

6.8

Z21

ICPC

Behaviour problem parent/fam memb

2.3

6.7

266

QBJ30

NOMESCO Finland

Correction of abdominal apron

1.9

6.7

511

L03.0

ICD-10 Finland

Cellulitis of finger and toe

1.3

6.7

465

3583

XLD00

NOMESCO Finland

Sytologyspecimen from mouth of uterus

1.2

6.7

1438

12519

F33.9

ICD-10 Finland

Recurrent depressive disorder, unspecified

1.3

6.7

409

3094

F53.0

ICD-10 Finland

Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified

3.0

6.7

122

R07.3

ICD-10 Finland

Other chest pain

1.3

6.7

570

4519

Z71.2

ICD-10 Finland

Person consulting for explanation of investigation findings

1.1

6.7

2013

17981

T82

ICPC

Obesity

1.4

6.7

334

2449

G02BA03

ATC

plastic IUD with progestogen

1.2

6.6

1559

13671

63498

ICD-8 Finland

Other complications of pregnancy, Graviditas prolongata

2.3

6.6

231

J01CF02

ATC

cloxacillin; systemic

1.7

6.6

123

722

-1

NOMESCO Finland

1.1

6.5

3205

29517

H02AB04

ATC

methylprednisolone; systemic

1.2

6.5

1105

9430

LCA16

NOMESCO Finland

Destruction of endometrium

1.6

6.5

152

951

66180

ICD-8 Finland

Occipital presentation

1.5

6.5

179

1165

LGA22

NOMESCO Finland

Hysteroscopic sterilisation

1.6

6.5

147

912

B01AB04

ATC

dalteparin; parenteral

1.4

6.5

280

2000

O34.1

ICD-10 Finland

Maternal care for tumour of corpus uteri

2.2

6.5

286

SFA40

NOMESCO Finland

Replacement of krone of tooth

1.2

6.5

1461

12772

O46.8

ICD-10 Finland

Other antepartum haemorrhage

2.4

6.5

208

J45.0

ICD-10 Finland

Predominantly allergic asthma

1.2

6.5

733

6008

Z00.0

ICD-10 Finland

General medical examination

1.2

6.5

1345

11678

M70.6

ICD-10 Finland

Trochanteric bursitis

1.2

6.5

911

7642

WYA30

NOMESCO Finland

Preparations for expected poor cooperation

1.3

6.5

615

4942

L15

ICPC

Knee symptom/complaint

1.2

6.4

1520

13331

R22.9

ICD-10 Finland

Localized swelling, mass and lump, unspecified

1.3

6.4

569

4532

MCA96

NOMESCO Finland

Other caesarean section

3.1

6.4

103

LA2AE

NOMESCO Finland

Ultrasound examination of ovarian cyst

1.4

6.4

259

1830

N05AH02

ATC

clozapine; systemic

0.5

6.4

824

M02AA10

ATC

ketoprofen; topical

1.2

6.4

1129

9669

G01AF01

ATC

metronidazole; vaginal

1.2

6.4

1006

8523

O44.1

ICD-10 Finland

Placenta praevia with haemorrhage

2.0

6.4

403

O66.5

ICD-10 Finland

Failed application of vacuum extractor and forceps, unspecified

2.4

6.4

203

6582B

ICD-9 Finland

Other problems associated with amniotic cavity and membranes, Delayed delivery after spontaneous or unspecified rupture of membranes

2.1

6.4

295

6400A

ICD-9 Finland

Haemorrhage in early pregnancy, Threatened abortion

1.8

6.3

103

581

5742A

ICD-9 Finland

Cholelithiasis, Calculus of gallbladder without mention of cholecystitis[CHOLECYSTOLITHIASIS SINE CHOLECYSTITIDE,SINE OBSTR]

1.7

6.3

123

733

B01AB01

ATC

heparin; parenteral

6.5

6.3

D10

ICPC

Vomiting

1.3

6.3

578

4626

R03BA05

ATC

fluticasone; inhalant

1.2

6.3

1552

13664

67006

ICD-8 Finland

+∞

6.2

6765A

ICD-9 Finland

Other disorders of the breast associated with childbirth, and disorders of lactation, Suppressed lactation

+∞

6.2

6741A

ICD-9 Finland

Other and unspecified complications of the puerperium, not elsewhere classified, Disruption of Caesarean wound

+∞

6.2

6744A

ICD-9 Finland

Other and unspecified complications of the puerperium, not elsewhere classified, Placental polyp

+∞

6.2

O88.1

ICD-10 Finland

Amniotic fluid embolism

+∞

6.2

8849

FHL

Other measure in this category

26.7

6.2

R01AD58

ATC

fluticasone, combinations; inhalant, nasal

1.1

6.2

2168

19547

N06AX11

ATC

mirtazapine; oral

1.1

6.2

2692

24602

G56.0

ICD-10 Finland

Carpal tunnel syndrome

1.2

6.2

1092

9351

SPAT1301

SPAT

No procedures

1.1

6.2

2439

22160

O68.1

ICD-10 Finland

Labour and delivery complicated by meconium in amniotic fluid

2.0

6.2

340

R23.8

ICD-10 Finland

Other and unspecified skin changes

1.2

6.2

1090

9336

SPAT1255

SPAT

Intravenous administration of medicine

1.3

6.2

365

2750

W03

ICPC

Antepartum bleeding

1.8

6.1

522

TLC00

NOMESCO Finland

Insertion of intrauterine device

1.2

6.1

808

6734

N06AB06

ATC

sertraline; oral

1.2

6.1

1001

8516

J01DC02

ATC

cefuroxime; systemic

1.3

6.1

475

3727

A10AC01

ATC

insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)

1.3

6.1

428

3310

J01CF05

ATC

flucloxacillin; systemic

1.5

6.1

214

1473

Z20.9

ICD-10 Finland

Contact with and exposure to unspecified communicable disease

1.4

6.1

272

1960

O23.5

ICD-10 Finland

Infections of the genital tract in pregnancy

1.7

6.0

113

665

LC2DE

NOMESCO Finland

Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods

1.3

6.0

501

3961

W81

ICPC

Toxaemia of pregnancy

4.9

6.0

NAME	O15_COMPLIC_PUERP
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	2
INCLUDE	O15_PUERP_SEPSIS\|O15_PUERP_INFECT_OTHER\|O15_VENOUS_COMPLIC\|O15_OBSTET_EMBOL\|O15_PUERP_ANEST_COMPL\|O15_PUERP_COMPL_NAS\|O15_BIRTH_BREAT_INFECT\|O15_BREAST_LACT_OTHER_DIS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	O8[5-9]\|O9[0-2]
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	O8[5-9]\|O9[0-2]
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Parameter	HR [95% CI]	p-value
O15_COMPLIC_PUERP	0.609 [0.51, 0.73]	< 0.001
Birth year	0.996 [0.99, 1.0]	0.298

N-year risk	Females	Males
1	0.058%	No data
5	0.406%	No data
10	0.948%	No data
15	1.831%	No data
20	3.258%	No data

Complications predominantly related to the puerperium

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints