No definition available.
Other disorders of breast and lactation associated with childbirth
EFO MESH Endpoint Browser PheWeb
O15_BREAST_LACT_OTHER_DIS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
680 |
4. Check minimum number of eventsNone |
680 |
5. Include endpointsNone |
680 |
6. Filter based on genotype QC (FinnGen only) |
680 |
Control definitions (FinnGen only)
- Control exclude
- O15_COMPLIC_PUERP
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
- Parent code in ICD-10
- O85-O92
- Name in latin
- Alii morbositates mammmae et perturbationes lactationis ad partum adjunctae
Similar endpoints
↥List of similar endpoints to
Other disorders of breast and lactation associated with childbirth
based on the number of shared cases.
Similar with more cases:
- Complications predominantly related to the puerperium
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3627 | 3627 | - |
| Only index persons | 3580 | 3580 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.10 | - |
| Only index persons | 0.13 | 0.13 | - |
| Median age at first event (years) | |||
| Whole population | - | 31.25 | - |
| Only index persons | - | 31.23 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 680 | 680 | - |
| Unadjusted period prevalence (%) | 0.23 | 0.23 | - |
| Median age at first event (years) | 31.64 | 31.64 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 629
- Matched controls
- 6289
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O92.7
ICD-10 Finland
Other and unspecified disorders of lactation
5316.1
323.0
307
*
O92.1
ICD-10 Finland
Cracked nipple associated with childbirth
473.2
85.2
83
*
O92.4
ICD-10 Finland
Hypogalactia
912.6
83.5
80
*
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
4.8
68.7
314
1084
Z32.1
ICD-10 Finland
Pregnancy confirmed
4.7
68.1
320
1134
SPAT1379
SPAT
Health check-up of pregnant person
4.4
66.4
385
1658
Z37.0
ICD-10 Finland
Single live birth
4.5
62.4
294
1020
Z39.2
ICD-10 Finland
Routine postpartum follow-up
3.9
57.7
382
1770
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
3.9
56.4
390
1861
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
3.8
54.1
379
1800
SPAT1197
SPAT
Extensive health check-up of expecting family
3.6
51.1
384
1896
WX307
NOMESCO Finland
Obstetric epidural analgesia
3.9
50.7
278
1056
SPAT1380
SPAT
Postpartum check-up
3.5
47.2
316
1395
ZXE00
NOMESCO Finland
One hour or less
3.3
43.5
373
1940
O92.6
ICD-10 Finland
Galactorrhoea
76.6
38.4
43
6
O92.0
ICD-10 Finland
Retracted nipple associated with childbirth
201.8
37.2
38
*
ZXD10
NOMESCO Finland
Scheduled procedure
3.1
36.5
293
1393
O92.2
ICD-10 Finland
Other and unspecified disorders of breast associated with childbirth
377.9
36.4
36
*
W78
ICPC
Pregnancy
2.9
35.7
380
2166
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
3.0
35.5
312
1567
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
3.0
34.9
304
1512
O92.5
ICD-10 Finland
Suppressed lactation
+∞
30.5
29
*
R2110
NOMESCO Finland
Giving the first information
3.8
24.2
114
350
O99.80
ICD-10 Finland
The fear of childbirth
3.3
24.1
136
481
67808
ICD-8 Finland
Mastitis and other disorders of lactation, Alia definitae
+∞
20.9
20
*
MA3AE
NOMESCO Finland
Combined first trimester screening
2.9
20.9
142
566
Z32
ICD-10 Finland
Pregnancy examination and test
7.2
20.8
51
76
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
2.4
20.0
206
1046
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
2.9
19.8
140
573
O80.0
ICD-10 Finland
Spontaneous vertex delivery
2.2
19.3
363
2429
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.5
18.6
177
854
Z3232
NOMESCO Finland
Midwife
2.4
18.1
187
941
SPAT1315
SPAT
Periodic health check-up of children and adolescents
3.4
18.1
92
298
MAX99
NOMESCO Finland
Assistance to normal delivery
2.3
17.4
208
1121
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
3.0
16.9
104
386
6764A
ICD-9 Finland
Other disorders of the breast associated with childbirth, and disorders of lactation, Failure of lactation
+∞
15.7
15
*
Z2221
NOMESCO Finland
Medical doctor
2.1
15.4
234
1387
TMA00
NOMESCO Finland
Episiotomy
3.1
15.2
89
317
N61
ICD-10 Finland
Inflammatory disorders of breast
3.7
15.1
67
194
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
8.0
14.8
33
43
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
7.0
14.7
36
54
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.0
14.6
317
2152
ZXD05
NOMESCO Finland
Urgent procedure
2.0
14.5
268
1706
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
24.4
13.9
19
8
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
2.1
13.7
201
1161
Z34
ICD-10 Finland
Supervision of normal pregnancy
2.5
13.7
119
539
RF210
NOMESCO Finland
NA
5.1
13.4
42
87
WX322
NOMESCO Finland
Combined spinal-epidural analgesia in obstetrics
4.0
13.3
54
145
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
41.0
13.2
16
*
W85
ICPC
Gestational diabetes
2.6
12.9
104
450
S44
ICPC
Skin, Preventive immunization/medic
6.7
12.8
32
50
O86.8
ICD-10 Finland
Other specified puerperal infections
+∞
12.5
12
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
12.2
232
1469
WX320
NOMESCO Finland
Spinalanesthesy
2.1
11.9
148
790
TQW30
NOMESCO Finland
Acupuncture
8.2
11.9
26
33
O85
ICD-10 Finland
Puerperal sepsis
66.2
11.6
13
*
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.1
11.6
148
801
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.0
11.0
159
904
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2.3
10.5
100
473
67809
ICD-8 Finland
Mastitis and other disorders of lactation, Unspecified
+∞
10.4
10
*
W90
ICPC
Uncompl labour/delivery livebirth
2.2
10.3
112
562
SPAT1196
SPAT
Monitoring of normal pregnancy
2.0
9.9
146
832
SPAT1246
SPAT
Screening of depression or other psychiatric problem
2.4
9.7
88
406
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
3.2
9.6
49
160
MWA00
NOMESCO Finland
Repair of wound dehiscence in obstetric surgery
50.7
8.7
10
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
8.4
151
916
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
8.4
192
1263
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.6
8.4
332
2547
Z39.1
ICD-10 Finland
Care and examination of lactating mother
3.0
8.4
48
170
6768X
ICD-9 Finland
Other disorders of the breast associated with childbirth, and disorders of lactation, Other disorders of lactation
+∞
8.3
8
*
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
2.1
8.3
96
491
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
2.8
8.2
53
203
O70.0
ICD-10 Finland
First degree perineal laceration during delivery
5.2
8.1
24
48
Z3226
NOMESCO Finland
Physiotherapist
2.0
7.9
107
585
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.7
7.9
193
1291
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
5.1
7.8
23
46
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
2.0
7.8
102
550
O71.4
ICD-10 Finland
Obstetric high vaginal laceration
6.0
7.7
20
34
O80.8
ICD-10 Finland
Other single spontaneous delivery
2.1
7.4
86
443
O92.3
ICD-10 Finland
Agalactia
+∞
7.3
7
*
Z39
ICD-10 Finland
Postpartum care and examination
3.4
7.3
33
100
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
3.1
7.3
38
128
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.8
7.0
124
746
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
2.8
6.9
42
156
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
2.0
6.9
94
517
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
3.3
6.8
32
100
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
6.8
376
3069
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
2.8
6.8
41
152
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
3.6
6.8
29
84
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
2.6
6.7
47
190
N64.3
ICD-10 Finland
Galactorrhoea not associated with childbirth
6.3
6.5
16
26
O32.1
ICD-10 Finland
Maternal care for breech presentation
2.2
6.5
66
320
O86.4
ICD-10 Finland
Pyrexia of unknown origin following delivery
70.5
6.4
7
*
SPAT1195
SPAT
Antenatal classes
2.1
6.4
71
360
6765A
ICD-9 Finland
Other disorders of the breast associated with childbirth, and disorders of lactation, Suppressed lactation
+∞
6.3
6
*
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
4.2
6.3
22
54
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
6.1
466
4049
G02CB01
ATC
bromocriptine; systemic
4.2
6.1
21
51
R3110
NOMESCO Finland
Psychosocial training
3.0
6.0
34
119
Mortality – FinRegistry
↥Association
Association between endpoint O15_BREAST_LACT_OTHER_DIS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have O15_BREAST_LACT_OTHER_DIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: O15_BREAST_LACT_OTHER_DIS – Other disorders of breast and lactation associated with childbirth
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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