Venous complications and haemorrhoids in the puerperium

O15_VENOUS_COMPLIC

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O87
  • Hospital discharge: ICD-9 671
  • Hospital discharge: ICD-8 671
  • Cause of death: ICD-10 O87
  • Cause of death: ICD-9 671
  • Cause of death: ICD-8 671

2 out of 7 registries used, show all original rules.

411

4. Check minimum number of events

None

411

5. Include endpoints

None

411

6. Filter based on genotype QC (FinnGen only)

404

Control definitions (FinnGen only)

Control exclude
O15_COMPLIC_PUERP

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O85-O92
Name in latin
Complicationes venosae in puerperio

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2932 2932 -
Only index persons 2824 2824 -
Unadjusted period prevalence (%)
Whole population 0.08 0.08 -
Only index persons 0.10 0.10 -
Median age at first event (years)
Whole population - 31.39 -
Only index persons - 31.32 -

-FinnGen-

Key figures

All Female Male
Number of individuals 404 404 -
Unadjusted period prevalence (%) 0.14 0.14 -
Median age at first event (years) 30.84 30.84 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
411
Matched controls
4110
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
67100
ICD-8 Finland
Puerperal phlebitis and thrombosis, Thrombophlebitis extremitatis inferioris
+∞
103.6
95
*
O87.0
ICD-10 Finland
Superficial thrombophlebitis in the puerperium
+∞
77.6
72
*
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
5.6
53.0
128
307
6712B
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Superficial thrombophlebitis[THROMBOPHLEB SUPERFIC EXTR INF,PUERP AIKANA]
+∞
40.3
38
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
5.0
40.3
105
264
PHD99
NOMESCO Finland
Resection of other vein
5.6
39.2
85
182
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
4.7
38.4
108
288
45499
ICD-8 Finland
Varicose veins of lower extremities, Other and unspecified, without ulcer
7.7
38.4
58
86
B01AB05
ATC
enoxaparin; parenteral
3.7
37.3
206
883
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
7.8
35.6
53
77
O87.1
ICD-10 Finland
Deep phlebothrombosis in the puerperium
+∞
34.9
33
*
B01AA03
ATC
warfarin; systemic
4.9
34.7
89
219
B01AB04
ATC
dalteparin; parenteral
7.3
33.7
53
82
PHD76
NOMESCO Finland
Resection of long saphenous vein
6.0
32.9
64
123
4549X
ICD-9 Finland
Varicose veins of lower extremities, Without mention of ulcer or inflammation
6.2
32.5
61
113
O87.2
ICD-10 Finland
Haemorrhoids in the puerperium
+∞
30.6
29
*
67101
ICD-8 Finland
Puerperal phlebitis and thrombosis, Thrombosis extremitatis inferioris
+∞
23.1
22
*
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
6.8
22.2
36
57
5611
FHL
Vena saphena Magna and / or swarm of nodule and possible local emissions
5.3
21.9
47
98
6718B
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Other venous complications[HAEMORRHOIDES ANI,PUERP AIKANA]
+∞
21.0
20
*
6715A
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Other phlebitis and thrombosis[PHLEBITIS/THROMBOSIS ALIA,RASKAUDEN AIKANA]
+∞
17.8
17
*
6714A
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Deep phlebothrombosis, postpartum[THROMBOPHLEB PROF EXTR INFER,RASKAUDEN AIKANA]
+∞
15.7
15
*
6712A
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Superficial thrombophlebitis[THROMBOPHLEB SUPERFIC EXTR INF,RASKAUDEN AIKANA]
+∞
15.7
15
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
3.0
15.1
75
282
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
7.1
15.0
23
34
PHM76
NOMESCO Finland
Endovenous obliteration of v.saphena magna
3.9
12.9
40
111
4511A
ICD-9 Finland
Phlebitis and thrombophlebitis, Of deep vessels of lower extremities
51.7
12.9
15
*
O87.3
ICD-10 Finland
Cerebral venous thrombosis in the puerperium
+∞
12.6
12
*
6714B
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Deep phlebothrombosis, postpartum[THROMBOPHLEB PROF EXTR INFER,PUERP AIKANA]
+∞
12.6
12
*
6718A
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Other venous complications[HAEMORRHOIDES ANI,RASKAUDEN AIKANA]
+∞
11.5
11
*
B01AB01
ATC
heparin; parenteral
+∞
11.5
11
*
5612
FHL
Local excisions and / or perforations of relapsing varicose veins
8.9
10.7
22
26
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
2.1
10.6
134
767
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
8.9
8.9
18
21
O60
ICD-10 Finland
Preterm labour and delivery
4.3
8.6
22
53
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.4
8.4
62
283
6715B
ICD-9 Finland
Venous complications in pregnancy and the puerperium, Other phlebitis and thrombosis[PHLEBITIS/THROMBOSIS ALIA,PUERP AIKANA]
+∞
8.4
8
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.1
8.3
98
541
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
1.9
8.2
155
1005
I82.9
ICD-10 Finland
Embolism and thrombosis of unspecified vein
9.2
8.1
16
18
V230A
ICD-9 Finland
Supervision of high-risk pregnancy, Pregnancy with history of infertility
6.6
7.8
19
30
PHM99
NOMESCO Finland
Endovenous obliteration of other vein
4.0
7.5
21
54
O87.9
ICD-10 Finland
Venous complication in the puerperium, unspecified
+∞
7.3
7
*
67000
ICD-8 Finland
Sepsis of childbirth and the puerperium, Endometritis
+∞
7.3
7
*
O22.0
ICD-10 Finland
Varicose veins of lower extremity in pregnancy
30.6
7.2
9
*
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
2.9
7.2
34
124
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
6.7
176
1240
W84
ICPC
Pregnancy high risk
3.1
6.7
28
95
SPAT1197
SPAT
Extensive health check-up of expecting family
2.0
6.7
80
442
KMAK, ,
NOMESCO Finland
1.7
6.5
242
1870
O80.8
ICD-10 Finland
Other single spontaneous delivery
2.8
6.5
33
125
OAA11, ,
SPAT
2.7
6.3
35
139
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.2
6.3
24
77
45100
ICD-8 Finland
Phlebitis and thrombophlebitis, Of lower extremities
27.1
6.2
8
*
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
3.1
6.2
26
88
SPAT1379
SPAT
Health check-up of pregnant person
2.0
6.2
68
364
M79.6
ICD-10 Finland
Pain in limb
1.7
6.1
191
1401

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
41
131
3.37
10.75
1.7
1.8
21.23
20.64
s
0.17
31
113
138
819
2.03
9.80
2.0
1.8
2.18
0.91
mg/l
0.94
106
625
25
65
4.03
8.82
1.2
1.2
2.80
6.96
u/ml
—
10
23
192
1311
1.87
8.77
20.4
9.0
1.26
1.11
inr
1.44
72
413
148
945
1.88
8.22
4.2
3.7
0.00
0.01
estimate
1.08
63
358
237
1808
1.73
6.84
3.8
3.3
0.00
0.02
estimate
0.80
65
345
235
1795
1.72
6.69
5.0
4.5
0.00
0.00
estimate
0.50
63
356
234
1797
1.70
6.43
3.9
3.3
0.00
0.00
estimate
-0.00
66
371
74
414
1.96
5.93
2.1
1.9
29.01
29.15
s
0.09
69
404
80
472
1.86
5.44
1.9
1.8
—
—
—
0
0
154
1102
1.64
5.25
3.1
3.0
13.94
23.92
ng/l
1.02
86
653
59
321
1.98
5.10
4.0
3.4
—
—
—
0
0
388
3577
2.51
4.69
13.1
12.1
3.93
3.92
mmol/l
0.58
379
3465
387
3565
2.47
4.66
13.1
12.0
139.88
139.78
mmol/l
0.43
378
3465
232
1865
1.56
4.65
3.7
3.9
6.29
6.43
mmol/l
0.64
214
1689
383
3544
2.18
4.03
14.1
11.3
19.70
19.78
mg/l
0.02
314
2695
138
1013
1.55
4.02
3.7
3.0
—
—
—
0
0
184
1442
1.50
3.92
3.7
3.1
6.00
5.86
ph
—
10
117
46
253
1.92
3.86
3.8
3.2
—
—
—
0
0
121
881
1.53
3.60
3.3
3.2
—
—
—
0
0
374
3454
1.92
3.60
5.7
5.2
1.71
2.13
mu/l
0.67
357
3219
286
2482
1.50
3.49
4.4
4.1
—
—
—
0
0
143
1085
1.49
3.48
2.7
2.6
—
—
—
0
0
396
3752
2.52
3.27
13.9
10.7
—
—
—
0
0
206
1696
1.43
3.20
2.8
2.4
—
—
—
0
0
334
3021
1.56
3.12
5.0
4.4
14.57
14.53
pmol/l
0.09
315
2803
45
264
1.79
3.11
2.4
2.9
1.23
1.24
mmol/l
0.22
38
231
77
526
1.57
3.01
2.0
1.7
—
—
—
0
0
127
968
1.45
2.95
2.3
2.0
151.13
140.68
u/l
0.16
118
914
217
1821
1.41
2.93
5.2
5.4
1.86
2.00
e9/l
0.92
204
1645
102
747
1.49
2.89
4.3
3.5
1.01
1.02
kg/l
0.59
14
100
202
1677
1.40
2.89
5.6
5.9
—
—
—
0
0
55
354
1.64
2.75
1.3
1.6
—
—
—
0
0
188
1555
1.39
2.69
9.2
8.0
0.00
0.00
e9/l
1.42
164
1275
8
20
4.06
2.58
1.4
1.4
—
—
—
0
0
396
3787
2.25
2.56
10.2
9.4
23.12
24.01
u/l
0.83
386
3665
88
643
1.47
2.51
2.4
2.3
7.79
9.07
e6/l
0.23
77
575
208
1763
1.36
2.50
5.2
5.5
0.52
0.53
e9/l
0.43
195
1552
133
1049
1.40
2.50
2.5
2.2
50.98
55.65
u/l
1.24
125
969
208
1767
1.36
2.45
5.3
5.5
0.04
0.04
e9/l
0.55
195
1556
95
710
1.44
2.40
2.0
1.7
—
—
—
0
0
214
1836
1.35
2.32
5.2
5.8
0.17
0.18
e9/l
0.24
200
1642
265
2352
1.36
2.27
3.2
3.3
—
—
—
0
0
34
205
1.72
2.19
3.0
2.2
19275.38
3968.58
u/l
1.36
20
93
6
161
0.36
2.06
2.3
2.3
—
—
—
0
0
102
794
1.38
2.03
3.6
3.3
—
—
—
0
0
5
11
4.59
1.94
1.0
1.2
—
—
—
0
0
14
65
2.19
1.90
4.0
3.2
3.88
4.77
e9/l
0.83
14
65
289
2639
1.32
1.81
7.1
6.7
73.01
76.55
u/l
1.22
276
2470
159
1343
1.30
1.80
4.4
4.0
36.05
36.36
g/l
0.30
147
1252
363
3437
1.48
1.80
4.3
4.1
5.70
5.77
mmol/l
0.63
339
3189
11
47
2.38
1.79
1.2
1.2
—
—
—
0
0
14
67
2.13
1.78
4.1
3.6
55.00
57.87
%
0.35
14
67
41
275
1.55
1.77
2.2
3.1
1.56
1.80
%
1.32
35
248
98
779
1.34
1.70
1.3
1.3
33.03
29.36
iu/ml
0.10
34
268
103
827
1.33
1.67
3.3
3.1
93.95
98.74
%
0.96
93
800
26
158
1.69
1.67
1.7
1.8
—
—
—
0
0
6
19
3.19
1.66
1.8
1.4
66.17
70.21
umol/l
—
6
19
228
2031
1.28
1.66
7.1
8.4
3.95
3.90
e9/l
0.13
208
1796
357
3381
1.43
1.65
3.6
3.6
1.19
1.23
mmol/l
0.60
337
3141
101
811
1.33
1.63
1.9
2.3
2845.10
6768.58
umol/l
0.71
92
716
369
3517
1.48
1.63
4.0
4.0
1.55
1.59
mmol/l
1.11
349
3294
194
1697
1.27
1.63
5.4
5.6
29.18
29.75
%
0.31
187
1590
189
1651
1.27
1.60
5.4
5.5
2.60
2.77
%
0.71
181
1538
0
43
0.00
1.53
0.0
1.6
—
95.53
—
0
43
5
15
3.36
1.52
1.4
1.7
137.00
142.93
nmol/l
—
5
15
6
21
2.88
1.51
1.3
1.3
—
—
—
0
0
34
228
1.54
1.49
2.5
2.3
—
—
—
0
0
34
229
1.53
1.47
2.5
2.8
—
—
—
0
0
188
1655
1.25
1.45
5.7
5.8
7.92
8.06
%
0.24
182
1543
287
2653
1.27
1.43
4.0
4.0
11.44
11.10
mm/h
0.18
269
2472
373
3578
1.46
1.42
4.5
4.5
2.94
2.89
mmol/l
0.55
353
3348
9
41
2.22
1.37
1.4
1.1
—
—
—
0
0
190
1684
1.24
1.35
5.1
5.4
57.06
55.99
%
0.57
184
1576
33
226
1.50
1.34
2.5
2.8
6.12
5.87
kpa
0.70
33
219
72
568
1.32
1.32
1.3
1.3
745.00
595.48
titre
0.18
16
124
337
3191
1.31
1.31
4.9
5.0
38.31
38.68
mmol/mol
0.42
319
2986
104
864
1.27
1.30
2.6
2.6
0.13
0.46
e6/l
3.56
84
624
179
1584
1.23
1.27
5.5
5.5
0.71
0.70
%
0.02
171
1464
368
3534
1.39
1.26
4.1
4.1
4.85
4.90
mmol/l
0.43
346
3321
6
25
2.42
1.25
1.3
1.2
—
—
—
0
0
180
1598
1.22
1.23
4.7
5.6
1.22
1.22
mmol/l
0.15
153
1342
31
215
1.48
1.20
4.0
5.8
1.34
1.27
mmol/l
0.18
31
210
22
142
1.58
1.17
2.0
1.5
—
—
—
0
0
8
39
2.07
1.16
1.4
1.3
—
—
—
0
0
7
30
2.36
1.13
1.1
1.0
—
—
—
0
0
13
73
1.81
1.12
1.0
1.3
—
—
—
0
0
22
144
1.56
1.11
2.9
2.8
—
—
—
0
0
64
512
1.30
1.08
1.7
1.6
1222.15
1177.97
nmol/l
0.16
55
383
102
864
1.24
1.07
2.5
2.5
—
—
—
0
0
194
1755
1.20
1.05
5.6
5.4
10.38
9.95
umol/l
0.19
183
1660
335
3195
1.26
1.05
14.3
13.7
15.27
14.57
%
1.16
330
3154
21
138
1.55
1.05
1.9
1.4
—
—
—
0
0
175
1569
1.20
1.05
1.9
2.0
—
—
—
0
0
73
597
1.27
1.04
2.7
2.4
506.33
504.67
mosm/kgh2o
0.02
61
509
195
1771
1.19
1.00
2.9
2.8
87.91
75.58
ug/l
0.47
186
1655
109
938
1.22
0.99
2.6
2.8
21.04
61.63
e6/l
1.40
85
687
9
49
1.86
0.99
3.1
2.1
—
—
—
0
0
9
49
1.86
0.99
1.1
3.0
—
—
—
0
0
5
23
2.19
0.98
1.2
1.6
1.11
1.04
g/l
—
5
23
32
234
1.40
0.97
1.2
1.2
—
—
—
0
0
84
705
1.24
0.96
3.3
3.5
—
—
—
0
0
123
1075
1.21
0.95
2.1
1.6
—
—
—
0
0
16
244
0.64
0.95
1.8
1.4
—
—
—
0
0
7
37
1.91
0.94
3.7
1.6
63.71
56.98
%
—
7
37
28
203
1.41
0.90
4.2
7.3
8.05
7.91
mmol/l
0.04
28
194
96
824
1.22
0.89
2.2
1.9
—
—
—
0
0
26
186
1.42
0.89
2.3
2.3
3.86
4.56
kpa
1.58
26
181
18
119
1.54
0.89
1.3
1.2
—
—
—
0
0
26
187
1.42
0.87
1.6
3.2
69.17
75.58
e9/l
0.53
20
136
34
257
1.35
0.86
4.3
4.0
0.11
0.15
%
—
9
61
8
44
1.83
0.86
2.6
2.5
—
—
—
0
0
8
141
0.56
0.84
1.1
1.7
—
—
—
0
0
16
105
1.55
0.83
4.0
3.9
—
—
—
0
0
107
937
1.19
0.81
1.2
1.3
1.33
2.10
u/ml
0.46
32
251
20
139
1.46
0.81
2.0
1.4
—
—
—
0
0
16
106
1.53
0.80
2.9
3.3
0.11
0.37
g/l
—
6
30
123
1092
1.18
0.80
2.2
2.0
—
—
—
0
0
21
148
1.44
0.79
3.3
3.7
5.30
5.20
kpa
0.23
21
142
13
82
1.60
0.79
1.4
1.3
—
—
—
0
0
24
174
1.40
0.78
1.3
1.3
4.76
0.85
u/ml
—
5
14
5
24
2.10
0.74
1.8
2.1
6.06
6.66
mmol/l
—
5
17
53
437
1.24
0.73
1.7
1.4
—
—
—
0
0
38
301
1.29
0.72
5.4
6.1
105.42
104.22
mmol/l
1.05
38
301
14
93
1.52
0.70
1.9
2.1
—
—
—
0
0
11
69
1.61
0.69
1.0
1.3
114.32
122.14
u/ml
—
6
14
14
94
1.51
0.67
1.4
1.2
3.26
3.75
mmol/l
1.35
14
86
7
43
1.64
0.67
1.1
1.0
—
0.03
—
0
11
10
62
1.63
0.65
1.2
1.5
—
—
—
0
0
58
492
1.21
0.63
1.2
1.2
—
—
—
0
0
5
30
1.67
0.61
2.6
1.6
—
—
—
0
0
21
276
0.75
0.60
1.2
1.4
—
—
—
0
0
0
22
0.00
0.59
0.0
20.4
—
1659.91
—
0
22
0
22
0.00
0.59
0.0
14.5
—
842.41
—
0
22
23
297
0.76
0.59
1.3
1.4
—
—
—
0
0
50
422
1.21
0.58
1.3
1.3
—
—
—
0
0
6
35
1.72
0.58
1.7
1.2
29.50
26.23
mg/l
—
6
29
39
470
0.81
0.57
2.3
2.2
12.24
14.03
umol/l
1.09
39
439
34
416
0.80
0.57
1.3
1.3
—
—
—
0
0
110
994
1.15
0.57
2.9
3.5
7.40
7.40
ph
0.32
29
190
128
1170
1.14
0.56
3.0
3.3
49.24
74.25
e6/l
0.42
93
751
18
133
1.37
0.56
1.7
1.4
1.12
1.20
g/l
0.55
18
127
108
976
1.14
0.56
1.7
1.7
1.38
1.35
mmol/l
0.15
84
828
9
61
1.49
0.54
3.3
3.9
—
—
—
0
0
14
100
1.41
0.52
1.1
1.1
—
110.00
—
0
8
17
126
1.36
0.52
1.7
1.5
0.20
0.24
g/l
0.89
17
121
64
561
1.17
0.50
3.3
3.5
231.26
317.04
ng/l
0.21
46
373
24
300
0.79
0.49
1.4
1.8
—
—
—
0
0
13
93
1.41
0.48
1.3
1.2
21.57
3.07
e6/l
—
7
70
231
2418
0.90
0.48
3.2
2.8
33.98
40.89
u/l
1.37
217
2281
22
277
0.78
0.48
1.2
1.2
—
—
—
0
0
34
282
1.22
0.48
4.5
3.8
1.50
0.98
%
—
10
84
10
142
0.70
0.47
1.6
1.3
—
—
—
0
0
7
48
1.47
0.47
1.4
1.1
—
—
—
0
0
26
318
0.81
0.45
4.7
3.8
3.45
9.27
ug/l
1.81
21
250
32
266
1.22
0.45
4.8
3.9
0.38
0.09
%
—
8
68
16
121
1.34
0.45
1.1
1.2
—
—
—
0
0
24
193
1.26
0.44
4.2
7.0
—
—
—
0
0
14
104
1.36
0.43
1.5
1.3
500.00
412.24
mg/l
0.38
14
97
6
95
0.63
0.42
2.5
1.7
9.20
1.44
ug/l
—
6
88
5
33
1.52
0.41
1.4
1.2
—
—
—
0
0
5
33
1.52
0.41
1.0
1.0
—
—
—
0
0
23
186
1.25
0.41
1.1
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
44.73
—
0
15
0
16
0.00
0.41
0.0
1.9
—
52.09
—
0
11
0
16
0.00
0.41
0.0
1.6
—
79.81
—
0
16
55
486
1.15
0.40
2.3
2.2
98.17
117.86
ug/g
0.30
43
376
124
1154
1.11
0.40
3.5
3.2
2.36
2.36
mmol/l
0.00
118
1030
37
317
1.18
0.39
1.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
11
80
1.39
0.39
1.2
1.1
—
—
—
0
0
11
80
1.39
0.39
1.2
1.1
—
—
—
0
0
5
36
1.39
0.38
1.8
3.3
—
—
—
0
0
5
37
1.36
0.37
1.2
1.2
—
—
—
0
0
145
1365
1.10
0.37
2.7
2.6
—
—
—
0
0
23
189
1.23
0.37
1.3
1.9
—
—
—
0
0
10
134
0.74
0.35
8.1
8.2
—
—
—
0
0
45
397
1.15
0.34
1.3
1.3
—
—
—
0
0
20
164
1.23
0.33
1.2
1.3
187.45
225.36
miu/ml
0.16
12
79
13
101
1.30
0.32
4.8
6.7
—
—
—
0
0
151
1436
1.08
0.30
4.4
4.9
1.23
1.22
mmol/l
0.34
141
1313
64
585
1.11
0.30
4.2
2.4
2.45
2.45
mmol/l
0.03
55
517
30
260
1.17
0.29
4.6
3.8
1.28
0.74
%
—
9
70
15
121
1.25
0.29
2.2
1.7
7.14
4.11
iu/l
—
8
45
40
356
1.14
0.28
1.3
1.2
87.38
170.32
iu/ml
1.28
13
152
39
347
1.14
0.28
1.3
1.4
—
—
—
0
0
24
279
0.85
0.28
1.3
1.3
—
—
—
0
0
31
274
1.14
0.25
1.3
1.2
182.78
214.60
u/ml
0.09
26
256
78
728
1.09
0.25
1.5
1.4
22.73
22.37
nmol/l
0.07
70
628
48
437
1.11
0.25
2.0
2.0
—
—
—
0
0
10
78
1.29
0.24
1.5
2.6
—
—
—
0
0
73
681
1.09
0.23
1.6
1.6
424.90
32297508.43
pmol/l
1.06
60
579
5
38
1.32
0.23
1.2
1.2
—
—
—
0
0
12
97
1.24
0.23
5.0
5.1
—
—
—
0
0
34
305
1.13
0.22
2.9
3.6
—
—
—
0
0
15
178
0.84
0.22
1.0
1.1
—
—
—
0
0
14
116
1.21
0.22
3.0
2.1
0.56
0.65
%
0.51
14
116
5
41
1.22
0.22
1.0
2.1
—
—
—
0
0
134
1284
1.06
0.22
1.9
1.9
102.68
99.65
pmol/l
0.27
77
619
48
441
1.10
0.21
1.5
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
12.1
—
101.60
—
0
5
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
2.9
—
10.04
—
0
12
0
12
0.00
0.21
0.0
2.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
44.83
—
0
6
13
155
0.83
0.20
1.2
1.4
—
—
—
0
0
49
453
1.09
0.20
1.2
1.2
—
—
—
0
0
13
154
0.84
0.19
1.2
1.4
—
—
—
0
0
7
58
1.21
0.18
3.7
2.2
13.56
13.41
%
—
7
58
13
153
0.84
0.18
1.2
1.4
—
—
—
0
0
13
153
0.84
0.18
1.2
1.4
—
—
—
0
0
83
789
1.07
0.17
1.3
1.4
2.22
2.23
g/l
0.02
49
473
29
263
1.11
0.17
1.4
1.3
29.10
30.22
iu/l
0.07
24
227
8
69
1.16
0.16
1.4
1.2
—
—
—
0
0
14
120
1.17
0.16
3.0
2.1
1.54
1.12
%
0.55
14
120
8
71
1.13
0.16
1.1
1.1
—
15.63
—
0
6
9
83
1.09
0.14
1.7
2.3
—
—
—
0
0
81
845
0.95
0.14
2.7
3.2
47.67
298.99
mg/l
1.00
47
500
80
766
1.06
0.14
1.4
1.3
6.19
10.54
u/ml
0.66
46
313
8
96
0.83
0.14
1.1
1.7
—
—
—
0
0
17
151
1.13
0.13
4.5
5.4
—
—
—
0
0
9
106
0.85
0.13
1.1
2.7
14.12
10.21
mg/l
—
9
98
30
280
1.08
0.10
5.6
7.1
12.92
12.76
kpa
0.07
30
270
30
280
1.08
0.10
5.7
7.2
5.34
5.22
kpa
0.28
30
270
91
881
1.04
0.10
4.7
6.5
—
—
—
0
0
5
46
1.09
0.09
1.0
1.1
—
—
—
0
0
10
87
1.15
0.09
1.0
1.0
—
—
—
0
0
13
145
0.89
0.09
1.2
1.4
—
—
—
0
0
6
54
1.11
0.09
1.3
1.1
—
—
—
0
0
6
57
1.05
0.08
1.0
2.1
—
—
—
0
0
91
935
0.97
0.08
2.5
3.0
6.49
6.86
mmol/l
0.39
82
805
5
63
0.79
0.08
1.0
1.1
—
—
—
0
0
45
469
0.95
0.07
2.1
2.5
3.15
4.26
e6/l
0.33
25
221
9
84
1.07
0.07
2.7
1.9
5.21
4.83
mmol/24h
—
9
74
11
122
0.90
0.07
1.2
1.4
—
—
—
0
0
10
111
0.90
0.06
1.0
1.1
—
—
—
0
0
11
121
0.91
0.06
1.1
1.2
—
—
—
0
0
14
151
0.92
0.05
1.2
1.2
—
—
—
0
0
29
279
1.04
0.04
5.3
7.1
1.48
1.41
mmol/l
0.02
23
228
36
371
0.97
0.03
1.4
2.1
8.70
5.32
umol/l
0.31
29
316
90
887
1.02
0.03
3.1
3.7
11.61
7.58
mg/mmol
0.24
56
507
15
157
0.95
0.01
8.5
7.8
23.34
25.36
mmol/l
1.64
15
150
13
136
0.95
0.00
2.5
2.8
0.17
0.20
e6/l
0.11
13
130
31
309
1.00
0.00
2.3
2.2
44.77
32.90
u/l
0.37
26
252
114
1141
1.00
0.00
3.6
2.8
26.98
28.53
u/l
0.48
106
1089
29
285
1.02
0.00
2.6
2.1
0.22
0.22
g/l
0.06
29
272
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
6
63
0.95
0.00
2.0
2.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
226.90
—
0
6
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
-0.00
1.6
2.5
0.63
0.79
nmol/l
—
7
59
0
7
0.00
-0.00
0.0
1.3
—
1.57
—
0
7
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.4
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
7.20
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
5
52
0.96
-0.00
1.0
2.5
8.86
8.15
kpa
—
5
52
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.02
—
0
7
5
57
0.88
-0.00
2.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
89
1.01
-0.00
1.7
1.7
—
—
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Mortality – FinRegistry

Association

Association between endpoint O15_VENOUS_COMPLIC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_VENOUS_COMPLIC.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_VENOUS_COMPLIC – Venous complications and haemorrhoids in the puerperium

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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