Complications of anaesthesia during the puerperium

O15_PUERP_ANEST_COMPL

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule only females	293373
2. Check conditions None	293373
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — O89 Cause of death: ICD-10 — O89 2 out of 7 registries used, show all original rules.	130
4. Check minimum number of events None	130
5. Include endpoints None	130
6. Filter based on genotype QC (FinnGen only)	130

Control definitions (FinnGen only)

Control exclude: O15_COMPLIC_PUERP

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF3
Parent code in ICD-10: O85-O92
Name in latin: Complicationes anaesthesiae in puerperio

NAME	O15_PUERP_ANEST_COMPL
CONTROL_EXCLUDE	O15_COMPLIC_PUERP
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	2
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	O89
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	O89
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Complications of anaesthesia during the puerperium based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	926	926	-
Only index persons	924	924	-
Unadjusted period prevalence (%)
Whole population	0.03	0.03	-
Only index persons	0.03	0.03	-
Median age at first event (years)
Whole population	-	29.67	-
Only index persons	-	29.66	-

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	130	130	-
Unadjusted period prevalence (%)	0.04	0.04	-
Median age at first event (years)	30.50	30.50	-

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
121: Matched controls
1209

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

O89.4

ICD-10 Finland

Spinal and epidural anaesthesia-induced headache during the puerperium

+∞

150.4

111

TAB22

NOMESCO Finland

Stoppin epidural fluid escape with coagulated blood

195.6

81.2

MCA10

NOMESCO Finland

Lower uterine segment caesarean section

5.2

15.1

186

G97.0

ICD-10 Finland

Cerebrospinal fluid leak from spinal puncture

12.0

7.5

O34.2

ICD-10 Finland

Maternal care due to uterine scar from previous surgery

3.8

7.0

101

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

252

2.06

3.44

2.2

2.7

9.5

12.4

ng/l

—

102

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

390

1.94

3.34

3.9

5.2

1.2

mmol/l

0.05

329

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

5.25

3.10

1.1

1.0

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

338

1.84

2.76

3.1

4.8

1.2

mmol/l

0.10

314

(3019225) pH of Specimen

2.39

2.50

3.8

4.4

—

(3029937) Albumin [Presence] in Urine by Test strip

280

1.80

2.41

2.8

3.2

0.0

estimate

0.00

121

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

361

1.68

2.09

1.7

1.8

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

527

1.61

1.91

4.9

3.8

—

(3048689) Calprotectin [Mass/mass] in Stool

179

1.80

1.91

2.0

2.5

78.8

74.4

ug/g

0.06

129

(3021879) Hepatitis B virus core Ab [Presence] in Serum

104

1.97

1.79

1.3

1.4

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

432

1.57

1.71

1.8

2.0

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

3.67

1.63

1.4

1.1

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

3.67

1.63

1.4

1.1

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

3.67

1.63

1.2

1.1

—

(3045424) Erythrocytes [Presence] in Urine

3.67

1.63

1.4

1.1

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

102

1.89

1.54

2.9

3.1

32.7

—

(3037467) Urinalysis macro (dipstick) panel - Urine

770

1.55

1.48

4.5

3.8

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

1.91

1.45

1.8

—

(3013512) EKG study

195

1.63

1.40

2.2

2.8

—

(3019060) Gas panel - Arterial blood

2.57

1.32

3.0

3.8

—

(3052851) Hemolysis interference index of Serum or Plasma

2.85

1.29

1.6

2.0

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.80

1.24

1.7

1.4

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.87

1.22

2.7

5.0

1.1

1.0

mmol/l

0.89

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

103

925

1.55

1.19

4.2

4.3

14.1

pmol/l

0.06

874

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.80

1.17

2.8

4.2

—

(3020891) Body temperature

2.56

1.16

2.8

5.5

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

109

996

1.58

1.11

7.3

7.5

94.6

95.9

ml/min/173m2

0.33

805

(3019832) Treponema pallidum Ab [Presence] in Serum

315

1.44

1.08

1.6

1.7

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

191

1.52

1.06

1.7

1.5

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

2.32

1.04

1.8

1.5

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

175

1.53

1.03

1.6

2.0

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

430

1.39

1.02

3.1

3.0

—

(3045414) Leukocytes [Presence] in Urine

2.06

1.01

1.4

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

0.00

0.99

0.0

3.0

—

23.9

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

0.99

0.0

3.3

—

50.2

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

2.28

0.95

1.5

7.5

0.7

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.28

0.95

1.5

7.5

1.2

1.3

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

2.28

0.95

1.7

1.2

—

(3014007) Fractional oxyhemoglobin in Arterial blood

2.20

0.93

1.5

7.3

96.9

93.6

—

(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma

1.64

0.89

4.3

2.4

11.3

27.4

u/ml

4.51

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.87

0.87

1.1

1.7

—

(3006315) Basophils [#/volume] in Blood

546

1.34

0.87

5.9

5.2

0.0

e9/l

0.36

497

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.83

0.86

1.5

1.4

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

1.62

0.86

1.5

1.6

—

(3021589) Normoblasts [#/volume] in Blood

479

1.34

0.85

7.0

6.8

0.0

e9/l

0.50

401

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

209

1.43

0.85

1.4

1.5

—

(3021601) Nitrite [Presence] in Urine by Test strip

540

1.32

0.82

4.3

4.2

0.0

estimate

0.00

122

(3000492) Spirometry study

100

0.48

0.81

1.0

1.3

—

(3009261) Glucose [Presence] in Urine by Test strip

543

1.31

0.78

3.1

3.0

0.0

estimate

0.00

118

(3047007) Chlamydophila sp Ab [Presence] in Serum

2.22

0.77

1.4

1.3

—

(3044290) Cell count panel - Cerebral spinal fluid

2.13

0.75

3.0

1.3

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

1.61

0.75

1.5

1.3

138.5

286.5

miu/ml

—

(3000850) Epithelial cells [#/volume] in Urine

188

1.41

0.73

1.9

2.3

3.5

11.4

e6/l

1.10

158

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.04

0.73

1.2

1.1

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

317

1.33

0.72

2.2

1.9

—

(3022096) Basophils/100 leukocytes in Blood

489

1.29

0.71

5.9

5.2

0.6

0.7

0.13

458

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

862

1.33

0.70

3.7

3.8

36.5

36.8

mmol/mol

0.14

829

(3035350) Ketones [Presence] in Urine by Test strip

541

1.28

0.67

3.2

3.0

0.0

estimate

0.00

120

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

116

1102

1.49

0.66

10.0

9.5

13.8

17.9

mg/l

0.93

818

(3043238) Trisomy 21 risk [Likelihood] in Fetus

1.51

0.64

1.3

1.5

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

239

1.33

0.63

2.6

1.7

—

(40760892) CBC W Ordered Manual Differential panel - Blood

304

1.30

0.63

3.9

4.0

—

(3041096) Erythrocytes [Presence] in Urine by Automated

342

1.29

0.62

3.0

2.5

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

1.69

0.62

1.4

1.3

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

352

1.29

0.62

2.3

2.1

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.60

0.0

1.1

—

(3013115) Eosinophils [#/volume] in Blood

570

1.24

0.56

6.0

5.6

0.2

e9/l

0.08

525

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

385

1.26

0.56

2.0

1.7

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

117

1.42

0.55

1.4

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.56

0.54

1.3

1.7

—

(3002030) Lymphocytes/100 leukocytes in Blood

533

1.23

0.53

5.9

5.1

30.4

30.1

0.07

510

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.52

0.52

2.0

1.8

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

407

1.24

0.52

1.6

1.5

—

(40761511) CBC panel - Blood by Automated count

123

1191

1.61

0.51

10.0

8.7

—

(40758558) Short blood count panel - Blood

253

0.75

0.51

4.4

6.7

—

(3022621) pH of Urine by Test strip

1.59

0.50

1.1

2.0

—

(3006504) Eosinophils/100 leukocytes in Blood

507

1.22

0.49

6.0

5.2

2.5

2.6

0.22

476

(3047352) Trisomy 18 risk [Likelihood] in Fetus

1.43

0.48

1.2

1.4

—

(3005033) Fetal Nuchal fold Thickness US

1.43

0.48

1.2

1.4

—

(3019069) Monocytes/100 leukocytes in Blood

508

1.22

0.48

6.4

5.4

8.2

7.7

0.69

482

(3013707) Erythrocyte sedimentation rate by Westergren method

789

1.22

0.47

4.2

3.6

9.3

7.9

mm/h

0.64

743

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

121

1.37

0.47

1.3

1.5

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

306

1.24

0.47

3.4

2.6

—

(3032080) INR in Blood by Coagulation assay

250

1.26

0.46

4.8

4.2

1.2

1.0

inr

—

(3007853) Bacteria identified in Skin by Aerobe culture

113

1.37

0.45

1.3

1.5

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.42

0.44

1.0

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

171

0.73

0.43

1.4

1.5

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.38

0.42

1.4

3.0

1.2

mmol/l

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.40

0.41

1.4

1.5

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.41

0.0

1.1

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

108

1033

1.27

0.41

3.9

4.2

—

(3044640) Blood type and Crossmatch panel - Blood

330

1.21

0.40

2.7

1.9

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.40

0.0

3.0

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

110

1056

1.27

0.39

5.2

4.9

1.6

2.7

mu/l

0.54

105

1004

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

246

1.23

0.38

1.9

1.7

1.3

0.6

mg/l

0.35

180

(3018010) Neutrophils/100 leukocytes in Blood

527

1.18

0.38

5.8

5.0

55.9

56.5

0.16

502

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.49

0.36

1.8

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

1.45

0.36

1.5

2.4

—

(3022145) Colonoscopy Study observation

100

1.33

0.35

1.3

—

(40768793) Breast Pathology biopsy report

1.32

0.33

1.5

1.2

—

(3015736) pH of Urine

435

1.16

0.31

2.6

2.8

—

(3018418) pH of Serum or Plasma

233

1.20

0.31

2.5

3.5

7.4

—

(3009542) Hematocrit [Volume Fraction] of Blood

106

1095

0.83

0.30

9.5

9.8

40.5

39.7

1.45

938

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

225

1.19

0.29

1.8

—

(3026782) Osmolality of Urine

179

1.21

0.27

1.8

2.0

447.9

565.8

mosm/kgh2o

1.38

150

(3044889) 12 lead EKG panel

612

0.88

0.27

3.1

2.4

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.21

0.27

1.1

1.2

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

1.25

0.26

1.2

1.5

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

126

0.78

0.25

1.1

1.4

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

116

1.23

0.23

1.2

1.4

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

116

1.23

0.23

1.2

1.4

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

116

1.23

0.23

1.2

1.4

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

116

1.23

0.23

1.2

1.4

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

327

1.14

0.22

1.3

1.8

1.6

u/ml

0.04

(40761536) Microorganisms panel - Urine sediment

107

1.24

0.22

2.6

2.7

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.20

0.21

1.4

1.3

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.3

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

0.21

0.0

1.9

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.5

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

2.4

—

105.1

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.21

0.0

1.0

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

2.4

—

3.9

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.4

—

(3016616) Dehydroepiandrosterone sulfate (DHEA-S) [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

6.7

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

2.4

—

(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.21

0.0

2.5

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.21

0.0

1.4

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

19.1

—

1936.7

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

12.7

—

979.7

—

(44813793)

0.00

0.21

0.0

1.2

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.20

0.0

2.5

—

1.1

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.20

0.0

2.5

—

6.5

—

(21494755) Public health laboratory ask at order entry panel

175

0.84

0.20

1.5

1.2

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

101

981

1.13

0.19

3.4

3.1

5.4

5.5

mmol/l

0.62

927

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.20

0.18

1.0

1.1

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

988

0.89

0.18

3.1

2.8

1.1

mmol/l

0.06

935

(3023368) Bacteria identified in Blood by Culture

167

1.16

0.18

2.7

3.1

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

245

1.13

0.17

1.6

1.3

1.0

6.2

u/ml

1.26

114

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.19

0.17

1.3

—

(4035726)

1.13

0.16

1.1

1.2

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.17

0.16

1.3

2.0

8.8

10.1

g/l

—

(3023511) Choriogonadotropin [Units/volume] in Urine

1.12

0.15

1.0

1.2

—

(3007164) IgA [Mass/volume] in Serum or Plasma

286

1.11

0.15

1.4

1.3

2.3

2.1

g/l

0.23

183

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

335

1.10

0.15

1.9

1.8

94.7

96.2

pmol/l

0.05

191

(36660697) Celiac disease serology panel - Serum

127

0.85

0.13

1.3

1.2

—

(3001019) Free T4 and TSH panel - Serum or Plasma

133

1.14

0.12

1.9

1.6

—

(3026008) Bacteria identified in Urine by Culture

270

1.10

0.12

2.4

2.1

—

(3050129) First trimester maternal screen panel - Serum or Plasma

134

1.13

0.11

1.4

1.5

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

1.17

0.10

1.0

1.3

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

342

1.07

0.09

4.4

3.0

24.6

26.4

u/l

0.30

330

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

1.06

0.08

1.2

1.6

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

1.04

0.08

1.5

2.1

—

(1761868) Lipid panel - Serum or Plasma

458

0.94

0.08

2.1

—

(3012516) Albumin [Mass/volume] in Urine

156

1.10

0.08

3.7

3.3

162.5

949.6

mg/l

—

102

(42870588) Differential panel, method unspecified - Blood

343

1.07

0.08

6.4

5.0

—

(1002224) Polysomnography panel

0.83

0.08

1.0

1.1

—

(4010399)

0.79

0.08

1.4

—

(40761535) Cells panel - Urine sediment

1.10

0.08

2.4

3.3

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

108

1.12

0.07

2.7

2.3

22.5

25.4

0.31

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.04

0.07

1.1

—

(3005322) IgE [Units/volume] in Serum or Plasma

0.88

0.07

1.5

1.2

51.1

370.1

u/ml

—

(3008898) HLA-B27 [Presence]

0.84

0.07

1.0

1.1

—

(40768804) Tissue Pathology biopsy report

495

1.05

0.06

2.2

1.9

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

238

1.06

0.05

1.6

1.3

9.7

31.5

iu/ml

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

101

1.10

0.04

1.1

1.4

224.1

275.0

mu/l

0.70

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

180

1.07

0.04

1.4

1.7

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

109

0.91

0.04

1.9

1.6

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

250

0.95

0.03

1.5

1.6

1.4

mmol/l

0.05

225

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

108

0.92

0.03

2.1

—

17.9

—

(3002256) Pathology report gross observation

132

1.07

0.02

1.1

1.2

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

142

1.06

0.02

1.4

1.3

73.3

125.7

iu/ml

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.08

0.02

1.1

1.5

—

(3020682) Albumin/Creatinine [Ratio] in Urine

164

1.04

0.00

3.9

4.0

33.5

10.8

mg/mmol

—

102

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

234

1.03

0.00

1.9

1.5

—

(3003694) ABO and Rh group [Type] in Blood

404

1.02

0.00

2.4

1.8

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

104

1044

0.98

0.00

3.3

3.2

2.9

mmol/l

0.14

991

(3000494) Fungus identified in Specimen by Culture

113

0.97

0.00

1.3

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

103

1033

0.99

0.00

3.3

3.1

4.7

4.8

mmol/l

0.56

987

(40768797) Stomach Pathology biopsy report

132

0.98

0.00

1.2

—

(36304419) Bacteria [Presence] in Urine

258

1.01

0.00

3.7

2.2

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

218

1.01

0.00

3.0

3.2

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

103

1028

1.01

0.00

3.4

3.1

1.5

mmol/l

0.38

981

(3042936) Bacteria identified in Isolate by Culture

125

0.96

0.00

2.6

1.9

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

626

1.01

0.00

7.2

8.2

3.7

4.0

e9/l

0.64

558

(3025941) Bacteria identified in Stool by Culture

1.01

0.00

1.1

1.2

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.0

1.0

—

(4198724)

0.00

0.0

1.1

—

(3028009) Chlamydia trachomatis IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(40761872) Peanut recombinant (rAra h) 2 IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

1.2

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

0.0

1.6

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

38.8

—

(44786774) Adalimumab [Mass/volume] in Serum or Plasma

0.00

0.0

4.2

—

8.8

—

(3045209) Lutropin/Follitropin [Ratio] in Serum or Plasma

0.00

0.0

1.0

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3011897) Casein IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

0.0

1.0

—

(3006922) Hepatitis E virus Ab [Presence] in Serum

0.00

0.0

1.1

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.0

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(4024509)

0.00

0.0

1.4

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(40760435) Tropomyosin IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3029023) Hepatitis E virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3018993) Complement total hemolytic CH100 [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.0

1.3

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

0.0

1.0

—

(3041806) Other cells [#/volume] in Blood by Manual count

0.00

0.0

2.3

—

(3016845) Adenovirus Ag [Presence] in Specimen by Immunofluorescence

0.00

0.0

1.0

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.0

1.0

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.0

1.4

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

13.7

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

0.00

0.0

2.0

—

(3007449) CD3+CD8+ (T8 suppressor) cells/100 cells in Blood

0.00

0.0

1.0

—

27.4

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.0

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

0.0

1.1

—

1890.3

—

(3026250) Tacrolimus [Mass/volume] in Blood

0.00

0.0

38.0

—

6.1

—

(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum

0.00

0.0

1.7

—

(1175426) CD3 cells/100 lymphocytes in Blood

0.00

0.0

1.5

—

75.3

—

(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum

0.00

0.0

4.7

—

19.9

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3044941) Cell count panel - Synovial fluid

0.00

0.0

1.3

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.00

0.0

1.0

—

88.8

—

(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk

0.00

0.0

1.0

—

(3002222) Hepatitis E virus IgM Ab [Presence] in Serum

0.00

0.0

1.0

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.94

0.00

2.4

2.9

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

0.0

1.3

—

(36304052) Adalimumab Ab [Units/volume] in Serum or Plasma

0.00

0.0

2.8

—

(43055514) Macroprolactin [Presence] in Serum or Plasma

0.00

0.0

1.0

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.6

—

(3006245) CD3-CD19+ cells/100 cells in Blood

0.00

0.0

1.5

—

8.0

—

(3034426) Prothrombin time (PT)

0.00

0.0

1.2

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

1.0

—

32.5

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint O15_PUERP_ANEST_COMPL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_PUERP_ANEST_COMPL.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: O15_PUERP_ANEST_COMPL – Complications of anaesthesia during the puerperium

GWS hits: 1

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Complications of anaesthesia during the puerperium

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints