Complications of anaesthesia during the puerperium

O15_PUERP_ANEST_COMPL

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule only females	293218
2. Check conditions None	293218
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — O89 Cause of death: ICD-10 — O89 2 out of 7 registries used, show all original rules.	133
4. Check minimum number of events None	133
5. Include endpoints None	133
6. Filter based on genotype QC (FinnGen only)	127

Control definitions (FinnGen only)

Control exclude: O15_COMPLIC_PUERP

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF3
Parent code in ICD-10: O85-O92
Name in latin: Complicationes anaesthesiae in puerperio

NAME	O15_PUERP_ANEST_COMPL
CONTROL_EXCLUDE	O15_COMPLIC_PUERP
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	2
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	O89
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	O89
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Complications of anaesthesia during the puerperium based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	926	926	-
Only index persons	924	924	-
Unadjusted period prevalence (%)
Whole population	0.03	0.03	-
Only index persons	0.03	0.03	-
Median age at first event (years)
Whole population	-	29.67	-
Only index persons	-	29.66	-

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	127	127	-
Unadjusted period prevalence (%)	0.05	0.05	-
Median age at first event (years)	30.43	30.43	-

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
133: Matched controls
1330

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

TAB22

NOMESCO Finland

Stoppin epidural fluid escape with coagulated blood

219.4

172.1

O89.4

ICD-10 Finland

Spinal and epidural anaesthesia-induced headache during the puerperium

+∞

165.3

122

MCA10

NOMESCO Finland

Lower uterine segment caesarean section

3.8

12.7

237

O34.2

ICD-10 Finland

Maternal care due to uterine scar from previous surgery

3.8

9.0

107

G97.0

ICD-10 Finland

Cerebrospinal fluid leak from spinal puncture

10.1

7.0

O82.0

ICD-10 Finland

Delivery by elective caesarean section

3.6

6.9

O47.0

ICD-10 Finland

False labour before 37 completed weeks of gestation

2.8

6.4

191

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

256

2.07

3.59

2.2

2.9

9.50

12.24

ng/l

—

105

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

5.25

3.10

1.1

1.0

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

399

1.86

3.03

3.9

5.3

1.22

mmol/l

0.01

341

(3029937) Albumin [Presence] in Urine by Test strip

285

1.81

2.51

2.8

3.3

0.00

estimate

-0.00

126

(3019225) pH of Specimen

2.35

2.43

3.8

4.3

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

536

1.70

2.33

3.1

2.4

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

370

1.72

2.32

1.7

1.8

—

(3048689) Calprotectin [Mass/mass] in Stool

180

1.78

1.87

2.0

2.4

78.78

73.95

ug/g

0.07

130

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

4.28

1.84

1.0

1.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

446

1.58

1.80

1.8

2.0

—

(3037467) Urinalysis macro (dipstick) panel - Urine

784

1.62

1.75

4.5

3.8

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

105

1.94

1.74

1.3

1.4

—

(3045424) Erythrocytes [Presence] in Urine

3.67

1.63

1.4

1.1

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

3.42

1.53

1.2

1.1

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

3.42

1.53

1.4

1.1

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

3.42

1.53

1.4

1.1

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

104

1.85

1.46

2.9

3.0

32.00

32.46

—

(3019832) Treponema pallidum Ab [Presence] in Serum

324

1.54

1.45

1.6

1.7

—

(3013512) EKG study

198

1.59

1.32

2.3

2.9

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

106

949

1.58

1.29

4.2

4.3

14.19

14.12

pmol/l

0.11

101

896

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

1.82

1.28

1.8

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.82

1.28

1.7

1.4

—

(3019060) Gas panel - Arterial blood

2.46

1.26

3.0

3.7

—

(3044290) Cell count panel - Cerebral spinal fluid

2.46

1.26

2.7

1.3

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

436

1.45

1.24

3.1

3.0

—

(3052851) Hemolysis interference index of Serum or Plasma

2.69

1.22

1.6

2.1

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

2.69

1.22

1.8

1.4

7.78

7.05

mmol/l

—

(3021601) Nitrite [Presence] in Urine by Test strip

545

1.42

1.18

4.4

4.3

0.00

estimate

-0.00

127

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

112

1022

1.61

1.17

7.2

7.8

95.21

96.06

ml/min/173m2

0.20

826

(3020891) Body temperature

2.56

1.16

2.8

5.5

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.77

1.13

2.8

4.2

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

214

1.52

1.13

1.4

1.5

—

(3009261) Glucose [Presence] in Urine by Test strip

548

1.41

1.13

3.1

0.00

estimate

-0.00

123

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.79

1.10

2.7

5.0

1.07

1.00

mmol/l

0.81

(3043238) Trisomy 21 risk [Likelihood] in Fetus

1.72

1.09

1.3

1.5

—

(3000850) Epithelial cells [#/volume] in Urine

190

1.53

1.08

1.8

2.3

5.43

11.77

e6/l

0.72

162

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

182

1.53

1.07

1.7

2.0

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

2.32

1.04

1.8

1.5

—

(3045414) Leukocytes [Presence] in Urine

2.05

1.01

1.4

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

0.99

0.0

3.2

—

50.21

—

(3035350) Ketones [Presence] in Urine by Test strip

548

1.36

0.98

3.2

3.1

0.00

estimate

-0.00

130

(3017143) Hepatitis C virus Ab [Presence] in Serum

195

1.48

0.96

1.7

1.5

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

2.28

0.95

1.7

1.2

—

(3000492) Spirometry study

102

0.47

0.94

1.0

1.3

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

2.20

0.93

1.5

8.8

0.70

0.72

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.20

0.93

1.5

8.8

1.17

1.29

—

(3021589) Normoblasts [#/volume] in Blood

494

1.35

0.91

6.9

7.2

0.00

e9/l

0.50

415

(3014007) Fractional oxyhemoglobin in Arterial blood

2.12

0.90

1.5

8.6

96.85

93.62

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

1.63

0.89

1.3

—

(3005033) Fetal Nuchal fold Thickness US

1.63

0.89

1.3

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.87

0.87

1.1

1.7

—

(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma

1.62

0.85

4.3

2.4

11.35

27.19

u/ml

4.49

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

122

1.55

0.85

1.3

1.5

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.79

0.84

1.5

1.4

—

(3022217) INR in Platelet poor plasma by Coagulation assay

282

1.38

0.84

4.9

7.1

1.14

1.06

inr

0.24

106

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

1.62

0.82

1.5

1.3

138.50

279.54

miu/ml

—

(3041096) Erythrocytes [Presence] in Urine by Automated

348

1.35

0.82

2.9

2.6

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

332

1.34

0.77

2.2

1.9

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

2.22

0.77

1.4

1.3

—

(40760892) CBC W Ordered Manual Differential panel - Blood

534

1.30

0.76

6.1

5.6

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.04

0.73

1.2

1.1

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

119

1128

1.52

0.73

10.1

9.7

13.75

18.25

mg/l

1.10

837

(3006315) Basophils [#/volume] in Blood

556

1.29

0.72

5.9

5.2

0.03

0.04

e9/l

0.38

508

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

243

1.36

0.72

2.6

1.9

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

102

1.53

0.71

1.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

366

1.30

0.68

2.3

2.1

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

1.69

0.62

1.4

1.3

—

(40761511) CBC panel - Blood by Automated count

126

1219

1.64

0.61

9.9

9.0

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

879

1.28

0.60

3.6

3.8

36.49

36.69

mmol/mol

0.11

846

(3044640) Blood type and Crossmatch panel - Blood

334

1.28

0.60

2.6

2.0

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.60

0.0

1.1

—

(3022096) Basophils/100 leukocytes in Blood

500

1.25

0.57

5.9

5.2

0.63

0.66

0.13

468

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

309

1.27

0.55

3.4

2.6

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.56

0.53

1.3

1.7

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

396

1.25

0.53

2.1

1.7

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

118

1.40

0.53

1.3

1.4

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

118

1.40

0.53

1.3

1.4

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

118

1.40

0.53

1.3

1.4

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

118

1.40

0.53

1.3

1.4

—

(3015736) pH of Urine

456

1.23

0.51

2.7

2.8

5.75

5.76

—

(3013707) Erythrocyte sedimentation rate by Westergren method

806

1.23

0.49

4.2

3.6

9.23

7.96

mm/h

0.56

759

(3022621) pH of Urine by Test strip

1.52

0.48

1.1

2.1

—

(3026782) Osmolality of Urine

184

1.30

0.47

1.7

2.1

476.22

547.41

mosm/kgh2o

0.76

154

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

111

1058

1.30

0.47

3.9

4.2

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

249

1.26

0.47

1.9

1.7

1.26

0.65

mg/l

0.35

181

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

174

0.72

0.47

1.4

1.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

121

1.37

0.47

1.4

1.5

—

(40758558) Short blood count panel - Blood

260

0.77

0.46

4.4

6.6

—

(3013115) Eosinophils [#/volume] in Blood

581

1.20

0.43

6.0

5.6

0.17

e9/l

0.10

535

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

113

1083

1.29

0.43

5.2

4.8

1.57

2.73

mu/l

0.55

108

1029

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.41

0.0

1.1

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.40

0.0

3.0

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

417

1.20

0.40

1.6

1.5

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.38

0.39

1.0

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.38

0.39

1.4

1.5

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

236

1.24

0.39

1.8

—

(3002030) Lymphocytes/100 leukocytes in Blood

546

1.18

0.38

6.0

5.0

30.41

30.16

0.07

522

(3007853) Bacteria identified in Skin by Aerobe culture

117

1.32

0.37

1.3

1.5

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

333

1.20

0.37

1.2

1.3

1.75

1.63

u/ml

0.04

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.48

0.36

2.0

1.8

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.45

0.36

1.8

—

(3050129) First trimester maternal screen panel - Serum or Plasma

136

1.29

0.36

1.4

1.5

—

(3006504) Eosinophils/100 leukocytes in Blood

519

1.17

0.36

6.2

5.1

2.49

2.66

0.37

490

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

1.41

0.35

1.5

2.1

—

(3022145) Colonoscopy Study observation

100

1.33

0.35

1.3

—

(3019069) Monocytes/100 leukocytes in Blood

520

1.17

0.35

6.7

5.3

8.06

7.70

0.44

493

(40768793) Breast Pathology biopsy report

1.32

0.33

1.5

1.2

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

129

0.76

0.29

1.1

1.4

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

1.24

0.29

1.4

1.6

—

(3007164) IgA [Mass/volume] in Serum or Plasma

292

1.17

0.29

1.4

1.3

2.28

2.07

g/l

0.18

187

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.31

0.28

1.9

6.0

106.13

105.37

mmol/l

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.31

0.28

1.4

2.9

1.23

1.22

mmol/l

—

(3018418) pH of Serum or Plasma

235

1.19

0.28

2.5

3.5

7.39

7.41

—

(3018010) Neutrophils/100 leukocytes in Blood

539

1.13

0.26

6.0

5.0

55.80

56.46

0.18

513

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

1.20

0.25

1.2

1.6

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

248

1.16

0.24

1.5

1.3

0.95

6.26

u/ml

1.26

113

(3009343) pH of Capillary blood

1.36

0.24

1.0

3.2

—

7.40

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

1003

0.88

0.22

3.1

2.8

1.14

mmol/l

0.05

950

(3016616) Dehydroepiandrosterone sulfate (DHEA-S) [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

7.33

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.5

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

0.21

0.0

1.9

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.4

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.3

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

67.64

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

2.4

—

3.90

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.1

—

37.20

—

(3011951) Aspergillus fumigatus IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

0.12

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

2.4

—

105.10

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

2.4

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.21

0.0

1.0

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

19.1

—

1936.67

—

(44813793) Dust mix specific IgE antibody measurement

0.00

0.21

0.0

1.2

—

(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.21

0.0

2.5

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

12.7

—

979.67

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.21

0.0

1.4

—

(3044889) 12 lead EKG panel

625

0.90

0.20

3.2

2.4

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.20

0.0

2.5

—

6.48

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.20

0.0

2.5

—

1.08

—

(21494755) Public health laboratory ask at order entry panel

175

0.84

0.20

1.5

1.2

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.16

0.18

1.0

1.1

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.15

0.16

1.1

1.2

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.13

0.16

1.3

—

(40761536) Microorganisms panel - Urine sediment

111

1.19

0.16

2.6

2.9

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

111

1.19

0.16

2.5

2.3

22.40

25.52

0.38

(4035726) Immunohistochemistry procedure

1.12

0.16

1.1

1.2

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

188

1.14

0.16

1.4

1.7

—

(3023511) Choriogonadotropin [Units/volume] in Urine

1.22

0.16

1.2

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.13

0.15

1.3

2.0

8.76

10.06

g/l

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

218

1.12

0.15

3.2

—

(3003694) ABO and Rh group [Type] in Blood

414

1.09

0.15

2.4

1.8

—

(3023368) Bacteria identified in Blood by Culture

170

1.14

0.14

2.7

3.5

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

103

1006

1.11

0.14

3.4

3.1

5.40

5.50

mmol/l

0.62

949

(3008898) HLA-B27 [Presence]

0.83

0.14

1.0

1.1

—

(1761868) Lipid panel - Serum or Plasma

464

0.92

0.13

2.1

—

(3001019) Free T4 and TSH panel - Serum or Plasma

133

1.14

0.12

1.9

1.6

—

(3026008) Bacteria identified in Urine by Culture

281

1.09

0.11

2.4

2.1

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

242

1.09

0.10

1.6

1.3

9.85

30.42

iu/ml

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.17

0.10

1.4

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

1.17

0.10

1.0

1.3

—

(1002224) Polysomnography panel

0.83

0.08

1.0

1.1

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

343

1.07

0.08

1.9

1.8

94.68

96.04

pmol/l

0.05

192

(4200892) Spirometry reversibility

0.77

0.08

1.4

—

(40761535) Cells panel - Urine sediment

1.10

0.08

2.4

3.3

—

(40768804) Tissue Pathology biopsy report

503

1.06

0.07

2.2

1.9

—

(3012516) Albumin [Mass/volume] in Urine

157

1.09

0.07

3.7

3.3

162.45

931.49

mg/l

—

104

(3005322) IgE [Units/volume] in Serum or Plasma

0.87

0.07

1.5

1.2

51.11

383.10

u/ml

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

238

1.06

0.05

2.0

1.5

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

349

1.04

0.04

4.4

3.0

24.64

26.37

u/l

0.31

337

(36304419) Bacteria [Presence] in Urine

260

1.05

0.03

3.7

2.2

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

102

1.09

0.03

1.1

1.4

224.09

273.05

mu/l

0.67

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

105

1043

1.03

0.01

3.4

3.1

1.51

1.54

mmol/l

0.45

997

(3013650) Neutrophils [#/volume] in Blood by Automated count

637

0.98

0.01

7.2

8.2

3.70

3.98

e9/l

0.66

568

(3042936) Bacteria identified in Isolate by Culture

126

0.95

0.00

2.6

2.0

—

(3002256) Pathology report gross observation

134

1.05

0.00

1.1

1.2

—

(36660697) Celiac disease serology panel - Serum

129

1.01

0.00

1.2

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

106

1059

1.00

0.00

3.3

3.2

2.86

2.90

mmol/l

0.17

1009

(3018095) Leukocytes [#/volume] in Urine

352

0.99

0.00

4.0

3.0

13.09

42.55

e6/l

0.96

218

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

253

0.99

0.00

1.5

1.6

1.38

1.37

mmol/l

0.02

227

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

105

1048

1.01

0.00

3.2

3.1

4.70

4.82

mmol/l

0.65

1003

(40768797) Stomach Pathology biopsy report

132

0.98

0.00

1.2

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

145

1.04

0.00

1.4

1.3

73.33

124.09

iu/ml

—

(3020682) Albumin/Creatinine [Ratio] in Urine

165

1.03

0.00

3.8

33.55

10.71

mg/mmol

—

103

(3000494) Fungus identified in Specimen by Culture

115

0.95

0.00

1.3

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

115

0.95

0.00

2.2

1.6

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.06

0.00

1.1

1.5

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3027831) CD3-CD16+CD56+ (Natural killer) cells/100 cells in Blood

0.00

-0.00

0.0

1.5

—

11.83

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

-0.00

0.0

1.0

—

32.50

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3029023) Hepatitis E virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3028009) Chlamydia trachomatis IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3006245) CD3-CD19+ cells/100 cells in Blood

0.00

-0.00

0.0

1.5

—

8.00

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.6

—

(3014300) Beta 2 glycoprotein 1 IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.4

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

13.65

—

(3025941) Bacteria identified in Stool by Culture

0.99

-0.00

1.1

1.2

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

-0.00

0.0

1.0

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum

0.00

-0.00

0.0

4.7

—

19.88

—

(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk

0.00

-0.00

0.0

1.0

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

88.80

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

1.6

—

(3006922) Hepatitis E virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.6

—

1.50

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.01

-0.00

1.1

—

(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3041806) Other cells [#/volume] in Blood by Manual count

0.00

-0.00

0.0

2.1

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3007449) CD3+CD8+ (T8 suppressor) cells/100 cells in Blood

0.00

-0.00

0.0

1.0

—

27.40

—

(3016845) Adenovirus Ag [Presence] in Specimen by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3002222) Hepatitis E virus IgM Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3000012) Reticulocyte production index

0.00

-0.00

0.0

1.0

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3011897) Casein IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

0.01

—

(3026250) Tacrolimus [Mass/volume] in Blood

0.00

-0.00

0.0

38.0

—

6.08

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(3045209) Lutropin/Follitropin [Ratio] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

-0.00

0.0

1.3

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

1.00

-0.00

1.5

2.1

—

(43055514) Macroprolactin [Presence] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.0

—

(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum

0.00

-0.00

0.0

1.8

—

43.20

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

-0.00

0.0

1.4

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.6

—

(36304052) Adalimumab Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.8

—

(40760435) Tropomyosin IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.0

—

(3044941) Cell count panel - Synovial fluid

0.00

-0.00

0.0

1.3

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3036180) Methadone [Presence] in Urine

0.00

-0.00

0.0

1.3

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

1.8

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.89

-0.00

2.4

2.9

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

1890.25

—

(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(1175426) CD3 cells/100 lymphocytes in Blood

0.00

-0.00

0.0

1.5

—

75.33

—

(40761872) Peanut recombinant (rAra h) 2 IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

1.23

—

(44786774) Adalimumab [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

4.2

—

8.80

—

Mortality – FinRegistry

↥

Association

Association between endpoint O15_PUERP_ANEST_COMPL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_PUERP_ANEST_COMPL.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: O15_PUERP_ANEST_COMPL – Complications of anaesthesia during the puerperium

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Complications of anaesthesia during the puerperium

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints