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This is a non-core endpoint: only basic statistics are computed.

Obstetric embolism

O15_OBSTET_EMBOL

cholesterol embolism: Blocking of a blood vessel by cholesterol-rich atheromatous deposits, generally occurring in the flow from a large artery to small arterial branches. It is also called arterial-arterial embolization or atheroembolism which may be spontaneous or iatrogenic. Patients with spontaneous atheroembolism often have painful, cyanotic digits of acute onset.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O88
  • Hospital discharge: ICD-9 673
  • Hospital discharge: ICD-8 673
  • Cause of death: ICD-10 O88
  • Cause of death: ICD-9 673
  • Cause of death: ICD-8 673

2 out of 7 registries used, show all original rules.

49

4. Check minimum number of events

None

49

5. Include endpoints

None

49

6. Filter based on genotype QC (FinnGen only)

49

Control definitions (FinnGen only)

Control exclude
O15_COMPLIC_PUERP

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O85-O92
Name in latin
Embolia obstetrica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 419 419 -
Only index persons 374 374 -
Unadjusted period prevalence (%)
Whole population 0.01 0.01 -
Only index persons 0.01 0.01 -
Median age at first event (years)
Whole population - 30.90 -
Only index persons - 30.37 -

-FinnGen-

Key figures

All Female Male
Number of individuals 49 49 -
Unadjusted period prevalence (%) 0.02 0.02 -
Median age at first event (years) 28.92 28.92 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
5
11
4.92
1.99
7.2
6.2
—
—
—
0
0
0
38
0.00
1.41
0.0
2.1
—
—
—
0
0
6
23
2.83
1.41
3.5
1.8
—
—
—
0
0
0
34
0.00
1.21
0.0
3.5
—
—
—
0
0
0
30
0.00
1.01
0.0
1.3
—
—
—
0
0
8
46
1.88
0.88
1.1
1.5
—
—
—
0
0
6
31
2.06
0.88
1.0
1.3
—
—
—
0
0
12
75
1.79
0.84
2.5
2.1
17.3
4.3
e6/l
0.47
12
66
0
24
0.00
0.81
0.0
1.4
—
—
—
0
0
16
112
1.64
0.76
2.8
2.6
—
—
—
0
0
19
141
1.57
0.71
18.2
4.2
1.8
1.1
inr
—
6
43
5
27
1.95
0.70
2.2
1.3
—
—
—
0
0
0
20
0.00
0.62
0.0
1.2
—
—
—
0
0
0
19
0.00
0.62
0.0
1.3
—
—
—
0
0
0
19
0.00
0.62
0.0
1.0
—
—
—
0
0
0
22
0.00
0.61
0.0
1.2
—
—
—
0
0
12
165
0.64
0.60
1.9
2.7
—
—
—
0
0
9
62
1.55
0.57
3.3
2.2
197.2
123.1
ug/g
—
9
53
9
63
1.52
0.56
2.6
1.8
—
—
—
0
0
6
39
1.61
0.55
1.0
1.1
—
—
—
0
0
16
121
1.48
0.53
2.0
2.2
—
—
—
0
0
11
77
1.55
0.51
1.4
1.5
363.9
538.4
pmol/l
1.83
11
65
21
169
1.42
0.51
1.9
2.0
97.7
100.2
pmol/l
—
5
76
7
104
0.62
0.45
10.3
5.9
—
—
—
0
0
5
32
1.62
0.44
1.2
1.4
—
—
—
0
0
18
145
1.38
0.42
2.4
3.2
21.6
15.9
ng/l
—
8
85
0
15
0.00
0.42
0.0
1.5
—
—
—
0
0
0
16
0.00
0.42
0.0
1.0
—
—
—
0
0
38
409
0.68
0.40
15.3
13.3
40.4
39.6
%
0.96
29
313
14
109
1.40
0.39
5.9
9.6
—
—
—
0
0
22
253
0.76
0.34
6.8
6.6
11.8
9.8
umol/l
0.64
22
239
44
419
1.49
0.28
4.0
4.3
5.6
5.8
mmol/l
0.77
44
387
13
106
1.31
0.26
3.6
3.2
—
—
—
0
0
12
98
1.30
0.24
1.3
1.3
3.9
1.7
u/ml
—
5
24
15
127
1.26
0.23
2.2
1.7
1.2
1.3
mmol/l
0.74
15
105
22
196
1.22
0.22
4.4
5.7
3.2
2.6
%
0.69
22
178
18
204
0.81
0.22
1.8
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
2.2
—
0
6
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
13
109
1.26
0.21
4.7
3.4
1.3
2.9
mg/mmol
—
8
69
6
48
1.28
0.21
2.0
1.8
—
—
—
0
0
15
173
0.81
0.21
3.6
3.3
—
—
—
0
0
0
13
0.00
0.21
0.0
2.4
—
25.5
—
0
13
6
49
1.26
0.21
2.2
2.1
35.0
22.0
%
—
6
44
15
129
1.23
0.20
1.5
2.1
78.4
90.4
u/l
0.51
15
123
5
69
0.69
0.18
1.0
1.2
—
—
—
0
0
10
119
0.80
0.18
2.6
3.1
—
—
—
0
0
22
199
1.19
0.18
4.4
5.8
54.3
56.0
%
0.26
22
181
16
141
1.20
0.16
3.4
2.7
—
—
—
0
0
8
96
0.80
0.15
2.6
3.8
—
—
—
0
0
13
113
1.20
0.15
1.6
1.4
—
—
—
0
0
22
203
1.15
0.12
4.4
6.0
30.5
29.7
%
0.15
22
183
34
326
1.14
0.09
5.8
4.5
11.2
11.6
mm/h
0.09
34
294
6
56
1.08
0.09
1.2
1.3
—
—
—
0
0
7
66
1.07
0.08
1.4
1.5
—
—
—
0
0
7
66
1.07
0.08
3.0
2.3
553.7
525.7
mosm/kgh2o
—
7
57
8
74
1.10
0.08
1.4
1.6
—
—
—
0
0
21
198
1.11
0.07
4.8
6.2
7.6
8.4
%
0.51
21
180
11
121
0.88
0.06
3.5
3.4
—
—
—
0
0
30
289
1.10
0.06
4.5
3.9
—
54.8
—
0
5
13
136
0.94
0.01
4.8
5.7
—
—
—
0
0
17
176
0.95
0.00
7.3
3.9
36.7
35.9
g/l
0.36
17
166
30
294
1.05
0.00
5.4
3.8
—
—
—
0
0
30
295
1.04
0.00
3.7
3.4
—
—
—
0
0
19
195
0.96
0.00
4.7
5.5
0.8
0.7
%
0.55
19
174
10
102
0.98
0.00
5.2
3.5
88.3
97.7
%
—
10
102
0
5
0.00
0.00
0.0
1.0
—
29.9
—
0
5
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
32.8
—
0
6
0
8
0.00
0.00
0.0
1.8
—
4.4
—
0
8
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
4.0
—
4.0
—
0
5
0
6
0.00
0.00
0.0
2.2
—
37.8
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
4.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
9
0.00
0.00
0.0
3.6
—
7.7
—
0
9
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
8.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
4.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
3.7
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
0
7
0.00
0.00
0.0
3.0
—
—
—
0
0
0
7
0.00
0.00
0.0
3.9
—
6.7
—
0
7
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
62.3
—
0
8
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
4.0
—
107.0
—
0
5
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_OBSTET_EMBOL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_OBSTET_EMBOL.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_OBSTET_EMBOL – Obstetric embolism

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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