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Degenerative macular diseases

DOID EFO Endpoint Browser PheWeb

MACULA_NAS

macular degeneration: Loss of vision in the central portion of the retina (macula), secondary to retinal degeneration. [ NCIT:P378 ]

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Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H35.39#
  • Cause of death: ICD-10 — H35.39#

2 out of 7 registries used, show all original rules.

5096

4. Check minimum number of events

None

5096

5. Include endpoints

None

5096

6. Filter based on genotype QC (FinnGen only)

4957

Control definitions (FinnGen only)

Control exclude
H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy
5
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H35
Name in latin
Striae angioides maculae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 33887 19783 14000
Only index persons 32124 18934 13190
Unadjusted period prevalence (%)
Whole population 0.49 0.57 0.39
Only index persons 0.62 0.70 0.50
Median age at first event (years)
Whole population 70.47 70.87 69.89
Only index persons 70.16 70.58 69.55

-FinnGen-

Key figures

All Female Male
Number of individuals 4957 2691 2266
Unadjusted period prevalence (%) 0.99 0.95 1.04
Median age at first event (years) 68.71 67.59 70.04

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
5096
Matched controls
50960
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H35.9
ICD-10 Finland
Retinal disorder, unspecified
127.9
318.8
161
13
H34.8
ICD-10 Finland
Other retinal vascular occlusions
105.1
307.7
202
20
H33.0
ICD-10 Finland
Retinal detachment with retinal break
918.3
307.7
422
5
H25.1
ICD-10 Finland
Senile nuclear cataract
3.2
307.7
2658
13009
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
120.3
307.7
440
40
CKC12
NOMESCO Finland
Photocoagulation of retina
75.4
307.7
358
51
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
4.2
307.7
3303
15514
XCW99
NOMESCO Finland
Other investigative procedure of eye
10.8
307.7
1742
2337
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.3
307.7
1594
4898
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
4503599627370496.0
307.7
5095
26
XCK10
NOMESCO Finland
Photography of fundus of eye
6.5
307.7
1220
2369
Z96.1
ICD-10 Finland
Presence of intraocular lens
6.4
307.7
2039
4829
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
165.3
307.7
191
12
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
4.2
307.7
3141
14064
XCD20
NOMESCO Finland
Photoangiography of eye
93.8
307.7
382
44
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
218.4
307.7
900
50
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
11.0
307.7
927
1012
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
372.2
307.7
563
17
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
129.2
307.7
281
23
WX140
NOMESCO Finland
Parabulbar anesthesy
26.4
307.7
1107
531
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
3502.8
307.7
907
*
H33.3
ICD-10 Finland
Retinal breaks without detachment
244.0
307.7
255
11
S01BC03
ATC
diclofenac; ophthalmic
10.3
307.7
390
407
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
11.5
307.7
1410
1647
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
345.3
307.7
1044
38
CJB10
NOMESCO Finland
Laser discission of secondary cataract
5.3
307.7
1231
2911
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
174.9
307.7
1022
73
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
656.0
307.7
682
12
H26.4
ICD-10 Finland
After-cataract
4.9
307.7
1387
3611
CKC10
NOMESCO Finland
Local photocoagulation of retina
115.2
307.7
231
21
H35.37
ICD-10 Finland
Macular holes
1326.2
307.7
481
*
S01BC05
ATC
ketorolac; ophthalmic
6.7
307.7
659
1109
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
41.0
307.7
903
266
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
136.8
307.7
893
79
CKD40
NOMESCO Finland
Endophotocoagulation of retina
792.2
306.5
299
*
S01ED51
ATC
timolol, combinations; ophthalmic
4.2
293.6
894
2441
H26.2
ICD-10 Finland
Complicated cataract
18.1
273.4
222
128
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
109.9
271.1
139
13
H35.7
ICD-10 Finland
Separation of retinal layers
2495.3
258.3
248
*
H43.1
ICD-10 Finland
Vitreous haemorrhage
12.9
245.8
240
194
H36.01
ICD-10 Finland
Diabetic maculopathy
106.8
243.0
125
12
H35.36
ICD-10 Finland
Macular cyst
1219.5
240.4
233
*
XCH00
NOMESCO Finland
Eye pressure measurement
5.3
222.1
477
975
XCK00
NOMESCO Finland
Perimetry
3.9
191.1
628
1785
CKC15
NOMESCO Finland
Panretinal photocoagulation
97.8
184.7
96
10
H20.1
ICD-10 Finland
Chronic iridocyclitis
14.4
183.0
167
120
H3601, E113,
ICD-10 Finland
+∞
177.1
169
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.2
164.3
2741
17552
S01EC01
ATC
acetazolamide; systemic
6.5
160.9
271
438
H36.00
ICD-10 Finland
Diabetic background retinopathy
54.5
160.2
91
17
H35.8
ICD-10 Finland
Other specified retinal disorders
474.0
140.0
139
*
S01ED01
ATC
timolol; ophthalmic
4.1
136.5
395
1018
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.8
135.7
323
715
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
13.4
135.0
128
98
ZXA10
NOMESCO Finland
Bilateral
2.3
133.3
1274
6396
ZX198
NOMESCO Finland
Other local administration
16.9
133.2
111
67
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
65.4
129.0
71
11
XCD10
NOMESCO Finland
Electrophysiological examination of eye
5.7
126.8
242
441
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
10.4
125.4
140
138
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
7.9
125.0
173
225
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
62.6
122.6
68
11
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
13.3
122.2
116
89
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
1196.3
120.3
117
*
S01EA05
ATC
brimonidine; ophthalmic
4.6
120.3
293
660
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
1175.4
118.2
115
*
ZXA05
NOMESCO Finland
Left side
2.1
118.0
1631
9406
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
11.7
117.4
121
106
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
16.6
116.7
98
60
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.3
112.9
1005
4855
114
Kela drug reimbursment
Glaucoma
2.6
112.3
768
3291
H3600, E113,
ICD-10 Finland
+∞
109.8
105
*
H25.8
ICD-10 Finland
Other senile cataract
2.3
108.3
941
4491
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
45.6
106.7
63
14
H3603, E113,
ICD-10 Finland
+∞
106.6
102
*
S01EE01
ATC
latanoprost; ophthalmic
2.8
103.7
567
2166
ZXA00
NOMESCO Finland
Right side
2.0
103.6
1697
10303
XCW10
NOMESCO Finland
Assessment of vision
7.8
101.9
142
186
CKD20
NOMESCO Finland
Removal of vitreous body substitute
507.9
100.9
100
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
208.1
98.8
102
5
H26.02
ICD-10 Finland
Presenil cataract
4.9
95.3
214
450
A10AA02, ,
ATC
5.1
93.5
202
411
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
5.0
90.8
199
410
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
27.6
88.3
60
22
H25.0
ICD-10 Finland
Senile incipient cataract
2.7
88.0
515
2031
A10AA01, ,
ATC
7.1
87.6
133
192
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.6
87.5
574
2395
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
135.3
87.3
93
7
WX142
NOMESCO Finland
Sub-tenon anesthesy
12.8
85.5
83
66
H35.6
ICD-10 Finland
Retinal haemorrhage
216.1
82.6
85
*
S01EC04
ATC
brinzolamide; ophthalmic
3.1
81.2
361
1225
WX002
NOMESCO Finland
Sedation and analgesia
2.0
80.5
1168
6708
A10AB01
ATC
insulin (human); parenteral
4.9
80.2
181
382
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
403.8
80.1
80
*
CKD15
NOMESCO Finland
Injection of vitreous substitute
+∞
79.4
76
*
H3603, E103,
ICD-10 Finland
+∞
78.3
75
*
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
770.0
77.5
76
*
S01EA03
ATC
apraclonidine; ophthalmic
7.9
76.1
105
136
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
75.2
72
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
74.6
563
2500
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
13.2
71.6
68
52
H40.0
ICD-10 Finland
Glaucoma suspect
2.4
71.2
537
2382
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.8
71.1
382
1437
CKC20
NOMESCO Finland
Cryopexy of undetached retina
148.1
69.1
73
5
CKC60
NOMESCO Finland
Local buckling of sclera using implant
677.3
68.2
67
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
67.9
65
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
18.5
66.5
53
29
H44.2
ICD-10 Finland
Degenerative myopia
29.6
66.2
44
15
H33.5
ICD-10 Finland
Other retinal detachments
16.3
65.0
55
34
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
27.7
64.8
44
16
ZXE00
NOMESCO Finland
One hour or less
1.6
60.2
1948
13920
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.3
59.8
230
714
H53.1
ICD-10 Finland
Subjective visual disturbances
2.6
59.3
376
1535
H3601, E103,
ICD-10 Finland
+∞
58.4
56
*
ZXD20
NOMESCO Finland
Day surgery
2.0
56.6
695
3724
H35.4
ICD-10 Finland
Peripheral retinal degeneration
89.7
56.0
62
7
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
7.0
55.8
85
123
H3600, E103,
ICD-10 Finland
+∞
55.3
53
*
A10AB04
ATC
insulin lispro; parenteral
4.3
53.8
139
327
A10AC01
ATC
insulin (human); parenteral
2.4
53.8
406
1794
H52.1
ICD-10 Finland
Myopia
4.2
53.7
144
349
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
4.1
53.0
150
378
A10AB05
ATC
insulin aspart; parenteral
2.3
52.4
406
1814
1LA05, ,
NOMESCO Finland
+∞
52.2
50
*
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.5
51.1
344
1443
CS494
NOMESCO Finland
Other visual field testing
3.4
49.7
179
533
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
11.4
49.1
51
45
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
247.3
48.1
49
*
Z3231
NOMESCO Finland
Registered nurse
1.6
47.4
1414
9774
S01EE03
ATC
bimatoprost; ophthalmic
3.2
46.1
192
625
T89
ICPC
Diabetes insulin dependent
3.5
46.0
159
461
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
8.6
44.7
57
67
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
44.3
1835
13634
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
13.2
44.2
42
32
A98
ICPC
Health maint/preventive medicine
2.0
43.8
4629
42437
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
43.8
42
*
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
221.9
43.0
44
*
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
94.9
42.8
47
5
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.5
42.0
150
444
S01EC03
ATC
dorzolamide; ophthalmic
3.7
41.9
135
373
N02BE01
ATC
paracetamol; systemic, rectal
1.8
41.7
4428
40149
S01EC54
ATC
brinzolamide, combinations; ophthalmic
4.0
41.1
119
305
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
40.9
2473
19771
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
40.0
547
3021
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
5.9
39.9
71
121
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
9.1
39.5
48
53
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
7.2
39.4
58
81
H30.2
ICD-10 Finland
Posterior cyclitis
390.5
39.1
39
*
H33.4
ICD-10 Finland
Traction detachment of retina
+∞
38.6
37
*
A10AE05
ATC
insulin detemir; parenteral
2.4
38.3
267
1136
S01EE05
ATC
tafluprost; ophthalmic
2.5
37.8
254
1063
A10AE04
ATC
insulin glargine; parenteral
1.9
36.5
471
2549
H04AA01
ATC
glucagon; nasal, parenteral
5.6
35.4
67
121
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
10.1
35.4
40
40
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
2.6
34.6
214
861
CA1ME
NOMESCO Finland
Ultrasound oculometry
5.7
34.2
63
111
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
2.5
34.0
222
917
H33.2
ICD-10 Finland
Serous retinal detachment
120.9
33.7
36
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
33.6
3054
25964
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.7
32.9
181
687
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
90.7
32.7
36
*
S01FA01
ATC
atropine; ophthalmic
7.4
32.6
47
64
S01EE04
ATC
travoprost; ophthalmic
2.9
32.6
158
561
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
9.0
32.4
40
45
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
7.3
30.9
45
62
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
11.5
30.9
32
28
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
12.0
30.7
31
26
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
3.0
30.7
141
486
A10AD01
ATC
insulin (human); parenteral
3.7
30.7
97
265
S01EX03, ,
ATC
2.7
29.9
161
605
H34.1
ICD-10 Finland
Central retinal artery occlusion
304.2
29.8
30
*
A02BC02
ATC
pantoprazole; systemic
1.4
29.5
3323
28999
H40.11
ICD-10 Finland
Low pressure glaucoma
2.7
29.3
154
571
H27.1
ICD-10 Finland
Dislocation of lens
6.1
29.2
50
82
CS2P4
NOMESCO Finland
Optic nerve head imaging
4.5
28.7
69
154
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
28.7
1845
14607
H34.2
ICD-10 Finland
Other retinal artery occlusions
104.0
28.7
31
*
H02AB06
ATC
prednisolone; systemic
1.4
28.5
2293
18854
H53.4
ICD-10 Finland
Visual field defects
3.0
28.3
126
427
J01DB01
ATC
cefalexin; oral
1.5
28.2
3843
34540
H35.3
ICD-10 Finland
Degeneration of macula and posterior pole
+∞
28.1
27
*
TCK00
NOMESCO Finland
Photosensitisation of choroid and retina
+∞
27.1
26
*
S01FA04
ATC
cyclopentolate; ophthalmic
4.1
27.0
74
183
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
9.4
26.2
31
33
XCH05
NOMESCO Finland
Eye pressure longterm registration
4.2
26.1
70
170
H54.7
ICD-10 Finland
Unspecified visual loss
5.5
25.5
49
90
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.3
25.3
201
906
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
25.1
1159
8602
Z2221
NOMESCO Finland
Medical doctor
1.4
24.9
1224
9185
S18
ICPC
Laceration/cut
1.4
24.8
2201
18242
S01BA04
ATC
prednisolone; ophthalmic
2.7
24.8
134
505
A10AE06
ATC
insulin degludec; parenteral
2.7
24.3
131
493
H57.1
ICD-10 Finland
Ocular pain
2.5
24.3
152
616
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
24.2
564
3610
CHD99
NOMESCO Finland
Other filtering operation
8.4
24.0
31
37
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
4.3
23.9
61
143
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
23.8
1453
11312
E10
ICD-10 Finland
Type 1 diabetes mellitus
4.5
23.8
57
127
C08CA01
ATC
amlodipine; oral
1.4
23.6
2087
17246
L04AA06
ATC
mycophenolic acid; systemic
3.3
23.3
86
261
R42
ICD-10 Finland
Dizziness and giddiness
1.4
23.0
1208
9154
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
9.1
22.9
28
31
CKD50
NOMESCO Finland
Endodiathermy of retina
+∞
22.9
22
*
SPAT1262
SPAT
Handing over of treatment supplies
1.5
22.5
866
6189
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
6.0
22.5
39
65
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
22.4
3300
29340
SPAT1325
SPAT
Vaccination
1.4
22.3
1759
14244
A10AA03, ,
ATC
5.2
22.2
45
87
AA1AD
NOMESCO Finland
CT of head and brain
1.4
22.1
1456
11457
M79.6
ICD-10 Finland
Pain in limb
1.4
22.0
1836
14991
H40.9
ICD-10 Finland
Glaucoma, unspecified
2.6
21.9
128
502
H3602, E113,
ICD-10 Finland
+∞
21.9
21
*
SPAT1312
SPAT
General health counselling
1.4
21.6
1388
10866
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
6.9
21.6
33
48
S01BA01
ATC
dexamethasone; ophthalmic
2.2
21.6
176
802
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.9
21.4
261
1382
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.7
21.4
119
455
Z94.0
ICD-10 Finland
Kidney transplant status
4.5
21.2
51
114
SPAT1263
SPAT
Sampling
1.3
21.1
1929
15933
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.1
20.9
208
1025
A02BC05
ATC
esomeprazole; systemic
1.3
20.8
1868
15381
127
Kela drug reimbursment
Transplant complication
3.8
20.7
62
164
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
20.6
1412
11154
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
5.3
20.6
41
78
L17
ICPC
Foot/toe symptom/complaint
1.4
20.6
1318
10300
H35
ICD-10 Finland
Other retinal disorders
30.1
20.5
27
9
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
20.5
586
3927
A10AD05
ATC
insulin aspart; parenteral
2.7
20.5
108
402
C10AA05
ATC
atorvastatin; oral
1.3
20.5
2168
18269
H43.3
ICD-10 Finland
Other vitreous opacities
3.4
20.3
72
213
H16.0
ICD-10 Finland
Corneal ulcer
2.1
20.3
192
929
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
19.9
1375
10866
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
19.8
19
*
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
19.7
1987
16598
H35.29
ICD-10 Finland
Other proliferative retinopathy
200.8
19.6
20
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.6
19.4
115
454
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
19.1
2849
25077
NHQ40
NOMESCO Finland
Amputation of toe
2.8
18.9
93
334
F29
ICPC
Eye symptom/complaint other
1.7
18.9
394
2446
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
18.9
1728
14214
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.4
18.9
1032
7839
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
5.6
18.6
35
63
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
7.0
18.6
28
40
B05DA
ATC
Isotonic solutions
5.0
18.5
39
78
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.5
18.4
44
98
UJF32
NOMESCO Finland
Coloscopy
1.4
18.3
1286
10162
177
Kela drug reimbursment
Insulin glargine 300 U / ml
3.0
18.3
78
259
S01BA07
ATC
fluorometholone; ophthalmic
2.9
18.3
84
291
SPAT1153
SPAT
Removal of sutures
1.3
18.3
1535
12459
Z01.2
ICD-10 Finland
Dental examination
1.3
18.0
1693
13953
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
2.5
17.8
110
444
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
7.3
17.8
26
36
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
+∞
17.7
17
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.4
17.7
1003
7657
C03CA01
ATC
furosemide; systemic
1.3
17.5
1852
15499
H44.0
ICD-10 Finland
Purulent endophthalmitis
28.9
17.4
23
8
103
Kela drug reimbursment
Diabetes, insulin-treated
1.3
17.2
1292
10299
S01ED02
ATC
betaxolol; ophthalmic
3.0
17.2
73
242
XKD00
NOMESCO Finland
Uroflowmetry
1.4
17.1
802
5924
E0000UV, ,
ATC
1.3
17.0
1785
14905
Z71.8
ICD-10 Finland
Other specified counselling
1.3
17.0
1197
9448
L03
ICPC
Low back symptom/complaint
1.4
16.7
1134
8898
137
Kela drug reimbursment
Uraemia requiring dialysis
4.2
16.6
43
102
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
16.6
2524
22086
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
16.6
1779
14890
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
16.6
713
5182
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
16.5
1143
8990
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.7
16.5
331
2034
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
16.4
1158
9138
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
2.9
16.3
76
266
G04CA02
ATC
tamsulosin; oral
1.3
16.3
1184
9382
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
3.3
16.2
59
178
SPAT1310
SPAT
Counselling related to known health issue
1.3
16.1
1408
11449
B05DB
ATC
Hypertonic solutions
4.9
16.1
35
72
CKD60
NOMESCO Finland
Anterior vitrectomy
3.4
16.1
58
174
H43.2
ICD-10 Finland
Crystalline deposits in vitreous body
7.1
16.1
24
34
R51.80
ICD-10 Finland
Headache
1.5
16.0
554
3862
L28
ICPC
Limited function/disability (L)
1.4
15.9
980
7569
C07AB07
ATC
bisoprolol; oral
1.3
15.8
2593
22846
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
33.5
15.7
20
6
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
2.3
15.6
121
541
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.6
15.6
338
2119
A12AA04
ATC
calcium carbonate; oral
2.9
15.5
73
257
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.8
15.3
245
1415
H21.0
ICD-10 Finland
Hyphaema
5.5
15.2
29
53
J01CA04
ATC
amoxicillin; systemic
1.3
15.2
3558
32682
C10AA01
ATC
simvastatin; oral
1.3
15.2
2359
20610
CKA10
NOMESCO Finland
Biopsy of vitreous body
28.7
15.2
20
7
A11CC03
ATC
alfacalcidol; systemic
2.3
15.1
111
486
H26.3
ICD-10 Finland
Drug-induced cataract
4.4
14.9
37
85
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
2.2
14.9
123
565
R01AD09
ATC
mometasone; nasal
1.3
14.8
1693
14229
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
2.3
14.8
108
471
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
14.7
2125
18377
D07AC01
ATC
betamethasone; topical
1.3
14.7
1563
13018
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.8
14.6
239
1389
N03AX16
ATC
[U] pregabalin
1.3
14.6
1036
8160
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
+∞
14.6
14
*
1LA01, ,
NOMESCO Finland
+∞
14.6
14
*
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
14.2
14.5
24
17
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.5
14.5
494
3430
R53
ICD-10 Finland
Malaise and fatigue
1.3
14.4
1081
8583
S29
ICPC
Skin symptom/complaint other
1.4
14.2
855
6563
R06.0
ICD-10 Finland
Dyspnoea
1.3
14.2
1294
10548
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
14.2
2058
17780
J01FF01
ATC
clindamycin; systemic
1.3
14.2
1127
9019
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
5.7
14.1
26
46
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.3
14.1
1185
9555
J01AA02
ATC
doxycycline; systemic
1.3
14.0
3594
33178
N03AX12
ATC
[U] gabapentin; oral
1.4
13.9
719
5384
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.3
13.9
1264
10300
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
2.6
13.9
77
296
H02.4
ICD-10 Finland
Ptosis of eyelid
2.0
13.8
144
724
H27.0
ICD-10 Finland
Aphakia
5.6
13.8
26
47
ZXD05
NOMESCO Finland
Urgent procedure
1.3
13.8
1314
10771
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
13.8
1898
16284
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
13.7
1251
10197
J02AC01
ATC
fluconazole; systemic
1.3
13.5
1461
12162
H30.8
ICD-10 Finland
Other chorioretinal inflammations
+∞
13.5
13
*
H30.1
ICD-10 Finland
Disseminated chorioretinal inflammation
+∞
13.5
13
*
T90
ICPC
Diabetes non-insulin dependent
1.3
13.5
1107
8886
J01FA10
ATC
azithromycin; systemic
1.3
13.4
2136
18618
K02.1
ICD-10 Finland
Caries of dentine
1.3
13.4
2155
18805
S01FA02
ATC
scopolamine; ophthalmic
3.3
13.4
49
149
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
13.4
1640
13866
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
5.0
13.3
28
56
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.6
13.3
74
285
CA1AD
NOMESCO Finland
Orbita CT
10.5
13.2
25
24
J01MA02
ATC
ciprofloxacin; systemic
1.3
13.2
1830
15691
L01
ICPC
Neck symptom/complaint
1.4
13.2
589
4300
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
3.5
13.1
45
131
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
13.0
1555
13093
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
11.0
13.0
24
22
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
3.2
13.0
49
152
N02AX02
ATC
tramadol; systemic, rectal
1.3
12.9
1954
16910
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
22.6
12.9
18
8
SPAT1260
SPAT
Consultation of another employee
1.4
12.8
788
6065
S97
ICPC
Chronic ulcer skin
1.6
12.8
298
1903
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.4
12.7
522
3752
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
12.7
1045
8385
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.5
12.7
462
3249
M01AB05
ATC
diclofenac; systemic, rectal
1.2
12.6
2808
25331
H53.2
ICD-10 Finland
Diplopia
1.9
12.6
148
776
CKD45
NOMESCO Finland
Endocryotherapy of retina
+∞
12.5
12
*
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
11.0
12.5
23
21
H20.8
ICD-10 Finland
Other iridocyclitis
5.2
12.5
25
48
F05
ICPC
Visual disturbance other
2.0
12.5
127
634
H31.0
ICD-10 Finland
Chorioretinal scars
130.3
12.4
13
*
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
13.2
12.4
21
16
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
12.3
986
7877
SFA10
NOMESCO Finland
One-surface restoration
1.2
12.3
2068
18075
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
1.7
12.2
230
1392
H81
ICPC
Excessive ear wax
1.3
12.0
854
6707
H53.8
ICD-10 Finland
Other visual disturbances
2.8
12.0
60
219
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
12.0
1339
11164
S01AX11
ATC
[U] ofloxacin
1.8
12.0
163
898
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.3
12.0
807
6292
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
12.0
1060
8584
H40
ICD-10 Finland
Glaucoma
2.6
11.9
69
271
R01AD12
ATC
fluticasone furoate; nasal
1.3
11.9
989
7941
UKC02
NOMESCO Finland
Cystoscopy
1.3
11.9
812
6344
J01MA12
ATC
levofloxacin; systemic
1.3
11.9
858
6757
WX408
NOMESCO Finland
General anesthesy, balanced
1.3
11.8
1085
8822
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.4
11.8
638
4805
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.4
11.8
506
3667
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
3.0
11.8
51
172
L04AX01
ATC
azathioprine; systemic
1.9
11.7
157
860
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
11.7
665
5050
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
11.7
1347
11265
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
11.7
1485
12562
S01GX01
ATC
cromoglicic acid; ophthalmic
1.4
11.7
673
5122
H54.5
ICD-10 Finland
Severe visual impairment, monocular
4.5
11.6
28
63
H34.9
ICD-10 Finland
Retinal vascular occlusion, unspecified
30.1
11.6
15
5
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
11.6
1442
12168
H46
ICD-10 Finland
Optic neuritis
4.1
11.6
31
76
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
11.5
1746
15059
N06AX11
ATC
mirtazapine; oral
1.3
11.5
1441
12168
SPAT1301
SPAT
No procedures
1.3
11.5
1477
12511
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
120.3
11.4
12
*
SFA20
NOMESCO Finland
Two-surface restoration
1.2
11.4
2121
18692
SDA03
NOMESCO Finland
Periodontal treatment
1.3
11.4
1380
11602
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.4
11.4
576
4292
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.4
11.4
437
3102
H01.0
ICD-10 Finland
Blepharitis
1.7
11.3
213
1288
M03BX02
ATC
tizanidine; oral
1.2
11.2
2399
21438
H40.19
ICD-10 Finland
Other primary glaucoma with open ventricular angle
4.9
11.2
24
49
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.6
11.1
241
1513
B01AC04
ATC
clopidogrel; oral
1.3
11.1
861
6842
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
3.6
11.0
35
97
K30
ICD-10 Finland
Functional dyspepsia
1.4
11.0
440
3147
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
2.0
10.9
108
534
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.3
10.9
930
7481
CHD00
NOMESCO Finland
Laser trabeculoplasty
2.3
10.9
76
327
M54.5
ICD-10 Finland
Low back pain
1.3
10.8
1389
11747
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
2.1
10.8
97
463
Z49.2
ICD-10 Finland
Other dialysis
3.8
10.7
32
85
H18.2
ICD-10 Finland
Other corneal oedema
5.6
10.7
20
36
M48.0
ICD-10 Finland
Spinal stenosis
1.4
10.6
631
4821
Z01.7
ICD-10 Finland
Laboratory examination
1.4
10.6
569
4281
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.4
10.6
463
3367
G04CB02
ATC
dutasteride; oral
1.5
10.5
372
2600
L04AX03
ATC
methotrexate; systemic
1.5
10.5
366
2551
C08CA13
ATC
lercanidipine; oral
1.3
10.5
713
5559
WZA90
NOMESCO Finland
Other medical or dental certificate
1.3
10.5
853
6818
G44.2
ICD-10 Finland
Tension-type headache
1.4
10.5
476
3484
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
110.3
10.4
11
*
H3602, E103,
ICD-10 Finland
+∞
10.4
10
*
L04AD02
ATC
tacrolimus; systemic
3.7
10.4
32
87
C02AC05
ATC
moxonidine; oral
1.6
10.4
217
1350
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
7.7
10.4
23
30
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
1.6
10.3
247
1588
SPAT1097
SPAT
Recording of ECG
1.3
10.2
701
5469
TK820
NOMESCO Finland
Peritoneal dialysis
4.5
10.2
24
53
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
3.6
10.2
33
93
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
2.9
10.1
46
160
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
10.1
930
7553
Z49.1
ICD-10 Finland
Extracorporeal dialysis
2.6
10.0
57
223
C08CA02
ATC
felodipine; oral
1.4
9.9
498
3704
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.3
9.9
972
7950
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.2
9.9
1340
11378
R05
ICD-10 Finland
Cough
1.3
9.9
872
7040
C10AA07
ATC
rosuvastatin; oral
1.2
9.9
1366
11626
L04AD01
ATC
ciclosporin; systemic
2.5
9.8
61
249
D01
ICPC
Abdominal pain/cramps general
1.4
9.8
411
2965
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.4
9.8
428
3110
V03AE02
ATC
sevelamer; oral
4.4
9.8
24
55
M45
ICD-10 Finland
Ankylosing spondylitis
2.3
9.8
71
311
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.5
9.8
333
2311
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
3.0
9.7
42
142
KMAK, ,
NOMESCO Finland
1.2
9.7
1867
16437
1LA04, ,
NOMESCO Finland
55.1
9.6
11
*
L82
ICD-10 Finland
Seborrhoeic keratosis
1.3
9.6
788
6297
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.4
9.6
449
3302
G47.3
ICD-10 Finland
Sleep apnoea
1.3
9.6
796
6374
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
2.5
9.6
58
234
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
3.2
9.6
37
117
CFW99
NOMESCO Finland
Other operation on conjunctiva
5.0
9.6
20
40
K85
ICPC
Elevated blood pressure
1.3
9.5
791
6338
B01AB05
ATC
enoxaparin; parenteral
1.2
9.4
1486
12809
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.3
9.4
758
6043
H03AA01
ATC
levothyroxine sodium; systemic
1.3
9.4
1006
8310
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.3
9.4
913
7455
H33
ICD-10 Finland
Retinal detachments and breaks
17.5
9.4
14
8
H35.1
ICD-10 Finland
Retinopathy of prematurity
+∞
9.4
9
*
CKC75
NOMESCO Finland
Removal of cerclage from sclera
+∞
9.4
9
*
CKD85
NOMESCO Finland
Removal of subretinal membrane or band
+∞
9.4
9
*
H3601, E107,
ICD-10 Finland
+∞
9.4
9
*
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
21.7
9.3
13
6
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.3
9.3
890
7257
F99
ICPC
Eye/adnexa disease other
3.0
9.2
39
130
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
9.2
1385
11872
M25.5
ICD-10 Finland
Pain in joint
1.2
9.2
1174
9889
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.2
9.2
1148
9648
J05AB01
ATC
aciclovir; systemic
1.3
9.2
876
7134
D64.9
ICD-10 Finland
Anaemia, unspecified
1.3
9.2
544
4155
A05
ICPC
Feeling ill
1.6
9.1
182
1120
H02.3
ICD-10 Finland
Blepharochalasis
1.5
9.1
294
2018
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.3
9.1
551
4219
M10
ICD-10 Finland
Gout
1.6
9.1
202
1278
SPAT1211
SPAT
Application of soft bandage
1.4
9.1
379
2733
R11
ICD-10 Finland
Nausea and vomiting
1.4
9.1
359
2564
CHD35
NOMESCO Finland
Laser goniopuncture
3.2
9.0
34
106
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.4
9.0
501
3789
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
2.9
9.0
41
143
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.3
9.0
779
6269
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.4
9.0
418
3071
TK800
NOMESCO Finland
Hemodialysis
2.1
9.0
82
395
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
9.0
1624
14181
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.3
8.9
700
5560
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.5
8.9
266
1799
H92.0
ICD-10 Finland
Otalgia
1.6
8.9
194
1223
C09CA01
ATC
losartan; oral
1.2
8.8
1213
10298
R03AC02
ATC
salbutamol; inhalant
1.2
8.8
2223
20014
F01
ICPC
Eye pain
2.0
8.8
95
487
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
9.5
8.8
17
18
H53.0
ICD-10 Finland
Amblyopia ex anopsia
3.3
8.7
32
98
M79.1
ICD-10 Finland
Myalgia
1.4
8.7
497
3772
SPAT1053
SPAT
Memory test
1.3
8.7
859
7022
H13
ICPC
Plugged feeling ear
1.3
8.7
898
7383
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
8.7
821
6678
N06AB06
ATC
sertraline; oral
1.4
8.6
347
2486
A10BB01
ATC
glibenclamide; oral
1.6
8.6
202
1295
H47.1
ICD-10 Finland
Papilloedema, unspecified
3.9
8.6
24
61
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.5
8.5
288
1996
R20.2
ICD-10 Finland
Paraesthesia of skin
1.5
8.5
228
1506
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
1.9
8.5
97
507
C09CA06
ATC
candesartan; oral
1.3
8.5
956
7939
C09AA05
ATC
ramipril; oral
1.2
8.4
1280
10970
C09AA02
ATC
enalapril; systemic
1.2
8.4
975
8117
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
1.9
8.4
106
572
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
1.7
8.4
135
785
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
2.7
8.4
43
160
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
1.3
8.4
882
7265
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.5
8.4
281
1946
S01AD03
ATC
aciclovir; ophthalmic
1.7
8.4
143
846
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
4.5
8.4
20
45
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
3.5
8.4
28
81
H54.6
ICD-10 Finland
Moderate visual impairment, monocular
4.6
8.3
19
41
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
+∞
8.3
8
*
37600
ICD-8 Finland
Detachment of retina, Primaria
+∞
8.3
8
*
P01BA02
ATC
hydroxychloroquine; oral
1.4
8.3
327
2332
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.3
8.3
740
5973
C01DA14
ATC
isosorbide mononitrate; oral
1.3
8.3
910
7529
N48.4
ICD-10 Finland
Impotence of organic origin
2.0
8.3
84
421
SPAT1254
SPAT
Administration of medicine
1.3
8.3
708
5684
R06AE09
ATC
levocetirizine; oral
1.4
8.3
445
3346
G04CB01
ATC
finasteride; oral
1.3
8.3
547
4242
R21
ICPC
Throat symptom/complaint
1.3
8.3
561
4367
D07AC13
ATC
mometasone; topical
1.2
8.2
1148
9748
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
8.2
1684
14847
SPAT1229
SPAT
Assessment of need for aid
1.4
8.2
398
2943
N03AE01
ATC
clonazepam; systemic
1.5
8.2
231
1542
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
1.9
8.2
99
527
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.4
8.2
350
2533
M02AA07
ATC
piroxicam; topical
1.2
8.2
1677
14785
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.3
8.2
551
4286
M01AH05
ATC
etoricoxib; oral
1.2
8.1
2407
21917
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.2
8.1
1261
10824
L16
ICPC
Ankle symptom/complaint
1.4
8.1
415
3096
D07AB02
ATC
hydrocortisone butyrate; topical
1.2
8.1
1171
9979
A10AD04
ATC
insulin lispro; parenteral
4.5
8.1
19
42
R4110, ,
SPAT
1.4
8.1
354
2573
M01AE01
ATC
ibuprofen; systemic, rectal
1.2
8.1
3881
36887
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.4
8.0
311
2214
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
8.0
1597
14039
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
2.9
8.0
36
125
M65.3
ICD-10 Finland
Trigger finger
1.6
8.0
170
1066
L04AA01
ATC
[U] ciclosporin
2.3
8.0
56
243
J01DA01
ATC
[U] cefalexin
1.2
7.9
2653
24392
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
3.3
7.9
29
89
A01
ICPC
Pain general/multiple sites
1.4
7.9
385
2850
UDC00
NOMESCO Finland
Ear microscopy
1.4
7.9
295
2086
V03AE01
ATC
polystyrene sulfonate; oral
2.3
7.9
56
244
C03DA01
ATC
spironolactone; oral
1.3
7.8
588
4640
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
3.1
7.8
32
105
P20
ICPC
Memory disturbance
1.3
7.8
802
6580
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.3
7.8
688
5545
H40.8
ICD-10 Finland
Other glaucoma
3.4
7.8
27
80
I50.9
ICD-10 Finland
Heart failure, unspecified
1.3
7.8
819
6742
Z2446
NOMESCO Finland
Social worker
1.5
7.7
227
1530
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
1.7
7.7
148
903
PD4CC
NOMESCO Finland
Very extensive arterigography of lower extremity with X-ray
2.8
7.7
37
133
NGQ20
NOMESCO Finland
Amputation of lower leg
3.0
7.7
32
106
3643
FHL
Vitrectomy through pars Plana
15.0
7.7
12
8
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
7.7
2684
24734
J31.0
ICD-10 Finland
Chronic rhinitis
1.5
7.7
267
1862
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
1.5
7.7
229
1549
NA1AD
NOMESCO Finland
Cervical spine CT examination
1.6
7.7
179
1147
J01FA09
ATC
clarithromycin; systemic
1.2
7.7
1114
9493
J01CF05
ATC
flucloxacillin; systemic
1.5
7.7
214
1428
R60.0
ICD-10 Finland
Localized oedema
1.3
7.6
583
4611
L12
ICPC
Hand/finger symptom/complaint
1.3
7.6
584
4620
UJF30
NOMESCO Finland
Ileoscopy through colon
1.4
7.6
395
2953
A10BB07
ATC
glipizide; oral
2.1
7.6
69
332
R06AE07
ATC
cetirizine; oral
1.2
7.6
1659
14685
N30.0
ICD-10 Finland
Acute cystitis
1.3
7.6
707
5732
Z49.0
ICD-10 Finland
Preparatory care for dialysis
2.6
7.6
41
157
CH2X4
NOMESCO Finland
Optical coherence tomography (OCT) of iris and iridocorneal angle
18.4
7.6
11
6
H40.6
ICD-10 Finland
Glaucoma secondary to drugs
18.4
7.6
11
6
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
1.4
7.6
378
2809
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.4
7.6
373
2766
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.3
7.6
743
6064
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.3
7.6
748
6111
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.3
7.6
652
5239
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
1.9
7.6
88
464
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
1.8
7.5
116
667
G04CA52
ATC
tamsulosin and dutasteride; systemic
1.3
7.5
446
3405
CHC05
NOMESCO Finland
Iridotomy
2.0
7.5
76
382
JN3AD
NOMESCO Finland
Abdominal CT examination
1.3
7.5
460
3532
R01AD08
ATC
fluticasone; nasal
1.2
7.5
981
8271
XF402
NOMESCO Finland
ECG with work load test
1.3
7.5
479
3700
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
3.0
7.4
31
103
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
1.5
7.4
232
1584
D82
ICPC
Teeth/gum disease
1.2
7.4
1179
10131
N05BA04
ATC
oxazepam; oral
1.2
7.4
1085
9247
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
4.4
7.4
18
41
WZC00
NOMESCO Finland
Treatment plan or consultation
1.2
7.4
1418
12402
R02
ICPC
Shortness of breath/dyspnoea
1.3
7.4
568
4496
S01EB01
ATC
pilocarpine; ophthalmic
2.5
7.4
43
171
I95.1
ICD-10 Finland
Orthostatic hypotension
1.5
7.4
201
1334
205
Kela drug reimbursment
Chronic hypertension
1.2
7.4
1455
12759
M35.3
ICD-10 Finland
Polymyalgia rheumatica
1.5
7.3
211
1417
U02
ICPC
Urinary frequency/urgency
1.3
7.3
594
4735
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
7.3
712
5804
H31.3
ICD-10 Finland
Choroidal haemorrhage and rupture
+∞
7.3
7
*
H31.4
ICD-10 Finland
Choroidal detachment
+∞
7.3
7
*
H3601, E117,
ICD-10 Finland
+∞
7.3
7
*
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
7.3
963
8122
M01AE02
ATC
naproxen; oral, rectal
1.2
7.3
2198
19982
P06
ICPC
Sleep disturbance
1.4
7.3
365
2717
N06AX21
ATC
duloxetine; oral
1.4
7.2
399
3013
R01BA52
ATC
pseudoephedrine, combinations; oral
1.2
7.2
1110
9504
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
3.3
7.2
26
79
SPAT1281
SPAT
Other administrative function
1.4
7.2
306
2214
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.4
7.2
305
2207
N30.9
ICD-10 Finland
Cystitis, unspecified
1.4
7.2
271
1920
L57.0
ICD-10 Finland
Actinic keratosis
1.3
7.2
563
4469
C03AA03
ATC
hydrochlorothiazide; oral
1.3
7.2
463
3579
-44
ICPC
Preventive immunization/medic
1.4
7.2
378
2835
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.4
7.2
300
2166
J01MA06
ATC
norfloxacin; oral
1.3
7.2
558
4426
B01AF02
ATC
apixaban; oral
1.3
7.1
660
5347
C07AB02
ATC
metoprolol; systemic
1.2
7.1
1046
8914
AN1
HP
Coronary angiography
1.3
7.1
570
4535
M01AH01
ATC
celecoxib; oral
1.2
7.1
773
6380
SPAT1009
SPAT
Measurement of intraocular pressure
2.1
7.1
66
321
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
3.4
7.1
24
70
L08
ICPC
Shoulder symptom/complaint
1.2
7.1
860
7185
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
2.9
7.1
31
106
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.3
7.1
396
2996
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.2
7.1
932
7854
H28.0*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic cataract
7.9
7.1
15
19
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.4
7.1
288
2069
P01AB01
ATC
metronidazole; oral, rectal
1.2
7.1
1542
13634
I48.1
ICD-10 Finland
Persistent atrial fibrillation
1.5
7.1
202
1356
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.4
7.0
375
2817
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
2.3
7.0
52
231
K59.09
ICD-10 Finland
Constipation, unspecified
1.4
7.0
303
2199
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
2.2
7.0
54
244
A02BC01
ATC
omeprazole; systemic
1.2
7.0
1235
10710
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
1.7
7.0
123
735
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
1.6
7.0
172
1117
H02.1
ICD-10 Finland
Ectropion of eyelid
2.1
7.0
63
304
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
1.5
7.0
189
1255
H02
ICPC
Hearing complaint
1.3
6.9
667
5428
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.4
6.9
340
2523
H50.2
ICD-10 Finland
Vertical strabismus
2.8
6.9
33
119
WX402
NOMESCO Finland
General anaesthesia
1.3
6.9
725
5964
H91.1
ICD-10 Finland
Presbycusis
1.4
6.9
362
2715
RJ420, ,
NOMESCO Finland
3.6
6.9
22
62
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.4
6.8
248
1746
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
2.5
6.8
41
166
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.4
6.8
299
2177
H18.1
ICD-10 Finland
Bullous keratopathy
4.1
6.8
18
44
H44.1
ICD-10 Finland
Other endophthalmitis
10.9
6.8
12
11
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
1.4
6.8
309
2264
A02BC03
ATC
lansoprazole; oral
1.2
6.8
1272
11090
R35
ICD-10 Finland
Polyuria
1.4
6.8
293
2128
R05
ICPC
Cough
1.2
6.8
909
7675
3745
FHL
Hard membrane girding, cerclage with coagulation
40.1
6.8
8
*
H22.1*D86.8
ICD-10 Finland
Iridocyclitis in sarcoidosis
40.1
6.8
8
*
M13.9
ICD-10 Finland
Arthritis, unspecified
1.4
6.7
266
1901
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
1.8
6.7
93
519
M01AE03
ATC
ketoprofen; systemic, rectal
1.2
6.7
1609
14328
H50.31
ICD-10 Finland
Intermittent exotropia
3.1
6.7
26
83
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.2
6.7
1247
10863
A07AA02
ATC
nystatin; oral
1.4
6.7
263
1879
S06.0
ICD-10 Finland
Concussion
1.3
6.7
409
3138
Z5132
NOMESCO Finland
Nursing associate professional
3.4
6.7
23
68
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.2
6.7
796
6638
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
1.7
6.6
108
632
N17
ICPC
Vertigo/dizziness
1.3
6.6
557
4460
G04CA01
ATC
alfuzosin; oral
1.3
6.6
522
4147
H54.3
ICD-10 Finland
Mild or no visual impairment, binocular
5.5
6.6
18
33
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
1.5
6.6
218
1508
H50.52
ICD-10 Finland
Exophoria
2.7
6.6
34
128
SGA02
NOMESCO Finland
Opening and preparing the root canals
1.3
6.5
402
3088
SPAT1216
SPAT
Assessment of functional ability
1.2
6.5
802
6709
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.4
6.5
300
2203
Z01.9
ICD-10 Finland
Special examination, unspecified
1.5
6.5
227
1587
A02BA02
ATC
ranitidine; systemic
1.2
6.5
901
7630
SPAT1377
SPAT
Polysomnography
1.7
6.5
106
622
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
1.4
6.4
337
2526
C01CA24
ATC
epinephrine; parenteral
1.6
6.4
157
1019
M54.3
ICD-10 Finland
Sciatica
1.5
6.4
218
1516
TAB00
NOMESCO Finland
Lumbar puncture
1.6
6.4
136
854
ZXD35
NOMESCO Finland
Usual procedure
1.6
6.4
128
792
R55
ICD-10 Finland
Syncope and collapse
1.3
6.4
512
4074
M14.6*A52.1
ICD-10 Finland
Charcot's or tabetic arthropathy
7.4
6.4
14
19
R50.9
ICD-10 Finland
Fever, unspecified
1.3
6.4
572
4615
I25
ICD-10 Finland
Chronic ischaemic heart disease
1.4
6.4
235
1659
171
Kela drug reimbursment
Degludekinsuliini
14.3
6.4
10
7
2501B
ICD-9 Finland
Diabetes mellitus, Diabetes with ketoacidosis[DIABETES MELLITUS CUM KETOACIDOSI ,TYYPPI I]
14.3
6.4
10
7
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
1.5
6.4
168
1109
S01.50
ICD-10 Finland
Open wound in oral cavity
2.4
6.4
42
178
A10AB06
ATC
insulin glulisine; parenteral
2.6
6.4
35
136
G04BD12
ATC
mirabegron; oral
1.3
6.4
576
4655
S02.51
ICD-10 Finland
Fracture of tooth, open
1.4
6.4
311
2307
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.3
6.3
470
3703
R07.0
ICD-10 Finland
Pain in throat
1.5
6.3
191
1298
H54.1
ICD-10 Finland
Severe visual impairment, binocular
8.1
6.3
13
16
CK2X4, ,
SPAT
8.1
6.3
13
16
A04
ICPC
Weakness/tiredness general
1.3
6.3
627
5121
M01AH02
ATC
rofecoxib; oral
1.3
6.3
575
4649
L13
ICPC
Hip symptom/complaint
1.2
6.3
816
6860
M54.4
ICD-10 Finland
Lumbago with sciatica
1.3
6.3
612
4986
R00.0
ICD-10 Finland
Tachycardia, unspecified
1.6
6.3
136
858
K59.0
ICD-10 Finland
Constipation
1.4
6.3
247
1765
R52.9
ICD-10 Finland
Pain, unspecified
1.3
6.3
366
2789
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
3.5
6.3
21
61
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
1.7
6.3
104
613
S22
ICPC
Nail symptom/complaint
1.4
6.3
245
1750
K03.64
ICD-10 Finland
Dental calculus supragingival
1.2
6.3
966
8265
CKD25
NOMESCO Finland
External drainage of subretinal fluid
+∞
6.2
6
*
Q82.84
ICD-10 Finland
Pseudoxanthoma elasticum
+∞
6.2
6
*
H360, E103,
ICD-10 Finland
+∞
6.2
6
*
H3603, E107,
ICD-10 Finland
+∞
6.2
6
*
H3601, E119,
ICD-10 Finland
+∞
6.2
6
*
F28
ICPC
Limited function/disability (F)
2.8
6.2
29
103
CJF15
NOMESCO Finland
Secondary implantation of skleral fixed artificial lens in posterior chamber
7.0
6.2
14
20
A97
ICPC
No disease
1.2
6.2
715
5938
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
1.5
6.2
209
1452
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.4
6.2
317
2368
ZYC01
NOMESCO Finland
Remote contact by phone
1.5
6.2
181
1222
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.3
6.2
527
4226
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.3
6.2
601
4897
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.5
6.2
163
1077
W19
ICD-10 Finland
Unspecified fall
1.3
6.2
404
3130
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
2.5
6.2
37
150
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
4.0
6.2
17
43
R04.0
ICD-10 Finland
Epistaxis
1.3
6.1
347
2632
D01BA02
ATC
terbinafine; oral
1.2
6.1
1018
8768
S22.3
ICD-10 Finland
Fracture of rib
1.4
6.1
273
1995
F16
ICPC
Eyelid symptom/complaint
1.5
6.1
177
1193
N06AA09
ATC
amitriptyline; systemic
1.3
6.1
405
3144
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.2
6.1
655
5398
Z00.8
ICD-10 Finland
Other general examinations
1.4
6.1
268
1955
25008
ICD-8 Finland
Diabetes mellitus, Complicatio alia definita
8.6
6.0
12
14
M10.9
ICD-10 Finland
Gout, unspecified
1.4
6.0
304
2266
C10AX09
ATC
ezetimibe; oral
1.2
6.0
635
5221
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.2
6.0
758
6353
Z3226
NOMESCO Finland
Physiotherapist
1.2
6.0
748
6261

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
4651
42027
2.22
57.05
23.7
20.0
3.99
3.99
mmol/l
0.11
4517
40806
4645
41958
2.21
56.92
23.4
19.9
139.48
139.60
mmol/l
1.94
4521
40797
3607
30505
1.62
51.54
5.0
4.2
15.34
14.38
mm/h
2.62
3272
27815
4232
37332
1.79
51.45
7.4
6.2
41.57
40.41
mmol/mol
10.96
3805
33769
4448
39910
1.90
50.15
20.1
16.7
25.60
26.36
mg/l
0.73
3687
32521
4712
43237
2.19
48.35
29.9
24.7
38.92
39.29
%
3.03
4392
39658
4158
36676
1.73
48.26
5.5
4.9
2.03
2.11
mu/l
0.77
3680
32858
4714
43268
2.19
48.24
29.9
24.6
6.88
6.88
e9/l
0.07
4553
41701
4713
43263
2.19
48.09
29.9
24.6
242.40
244.24
e9/l
1.09
4567
41876
4714
43277
2.19
48.06
30.1
24.8
131.29
132.50
g/l
6.35
4626
42433
4713
43269
2.19
47.97
29.8
24.6
91.76
91.64
fl
1.07
4626
42407
4713
43269
2.19
47.97
29.8
24.5
30.39
30.39
pg
0.01
4626
42404
4713
43271
2.19
47.93
29.9
24.6
4.35
4.39
e12/l
5.30
4549
41708
3795
32820
1.61
46.16
8.3
7.5
82.46
80.53
u/l
0.97
3541
30692
4391
39469
1.81
46.03
5.8
5.3
2.53
2.63
mmol/l
11.59
3897
35489
4602
41988
1.99
46.01
13.0
11.0
24.24
24.67
u/l
0.60
4378
40101
3540
30302
1.55
43.23
4.5
4.0
15.11
15.06
pmol/l
0.57
3110
26982
2395
18969
1.50
41.89
6.9
6.1
—
—
—
0
0
2526
20264
1.49
41.22
6.2
5.5
0.04
0.04
e9/l
0.57
2192
17199
4238
38009
1.68
41.00
5.2
4.6
1.47
1.47
mmol/l
0.13
3736
34079
2568
20687
1.49
40.93
6.4
5.6
1.79
1.89
e9/l
1.48
2258
17938
2514
20189
1.48
40.55
6.2
5.5
0.62
0.62
e9/l
0.77
2182
17132
4267
38373
1.69
40.42
5.2
4.7
4.44
4.54
mmol/l
8.05
3790
34672
1976
15161
1.50
39.73
3.3
3.2
1786.78
1729.27
ng/l
0.20
1710
13156
3409
29217
1.50
38.95
5.5
4.7
—
—
—
0
0
4455
40635
1.77
38.85
19.5
16.1
—
—
—
0
0
2720
22299
1.47
38.79
21.2
18.5
1.35
1.35
inr
0.10
832
6145
2579
20929
1.47
38.73
6.5
5.7
0.19
0.19
e9/l
0.02
2247
17996
2253
17813
1.47
38.63
4.6
4.1
69.47
74.99
ng/l
0.06
1785
13550
2410
19379
1.46
37.46
2.2
2.1
95.72
93.68
pmol/l
1.20
1215
9827
2859
23776
1.46
37.13
8.8
8.6
4.40
4.25
e9/l
2.20
2512
20498
4102
36732
1.60
37.13
4.6
4.1
1.28
1.28
mmol/l
0.14
3586
32561
2806
23268
1.46
36.88
7.3
6.4
1.21
1.21
mmol/l
0.44
2293
19602
3353
28794
1.48
36.65
5.8
5.2
2102.76
1743.95
e6/l
0.13
75
474
1814
13848
1.48
36.56
2.3
2.1
167.34
226.45
u/l
2.44
1675
12873
4303
39028
1.66
36.47
5.6
5.0
6.13
6.03
mmol/l
5.79
3766
34698
2412
19499
1.45
35.86
6.8
5.9
25.66
26.39
%
2.57
2245
18035
2375
19154
1.45
35.71
6.8
6.1
8.93
8.85
%
0.52
2202
17668
2574
21094
1.45
35.39
6.5
5.7
1.21
1.21
mmol/l
0.23
2288
19030
2362
19051
1.45
35.37
6.5
5.8
2.81
2.83
%
0.10
2192
17553
2303
18491
1.45
35.32
6.5
5.8
0.66
0.66
%
0.31
2131
17022
2372
19182
1.44
34.82
6.4
5.7
59.10
58.36
%
2.24
2204
17724
3038
25815
1.44
33.43
5.2
4.6
7.00
6.78
mmol/l
5.69
2868
24212
2201
17655
1.43
33.22
11.7
10.1
0.00
0.00
e9/l
0.20
1826
14319
2493
20498
1.42
32.56
4.8
4.1
0.00
0.00
estimate
1.60
541
4092
2487
20471
1.42
32.10
6.4
5.5
0.00
0.00
estimate
0.50
487
3739
2508
20715
1.41
31.51
4.8
4.1
0.00
0.00
estimate
0.80
483
3680
2175
17577
1.41
30.65
2.5
2.2
80.90
79.64
nmol/l
1.20
1860
15355
2048
16452
1.41
29.51
3.4
2.8
150.17
149.83
ug/l
0.02
1818
14873
1958
15676
1.40
28.46
4.5
3.9
127.26
124.63
e6/l
0.04
1438
11298
2390
19816
1.39
28.09
5.0
4.5
34.48
34.68
g/l
0.89
2199
18222
2041
16484
1.40
28.06
4.3
3.8
5.92
5.80
ph
0.54
84
690
1726
13549
1.41
27.98
4.9
4.4
—
—
—
0
0
2690
22777
1.38
27.64
5.9
6.0
12.39
11.99
umol/l
0.53
2522
21570
1931
15615
1.38
25.65
3.1
3.3
2.35
2.36
mmol/l
1.74
1646
13402
2753
23591
1.36
25.19
3.5
3.1
55.89
53.56
u/l
0.56
2499
21370
2032
16605
1.37
25.14
2.3
2.2
—
—
—
0
0
3705
33344
1.41
24.79
22.8
19.8
15.51
15.36
%
0.70
3630
32662
1714
13710
1.38
23.89
3.8
3.4
131.20
81.05
e6/l
0.32
1351
10583
1459
11470
1.38
22.27
1.6
1.6
21.27
20.34
nmol/l
1.31
1208
9712
1692
13621
1.36
22.26
2.8
2.5
59.77
65.82
u/l
0.46
1541
12483
692
4736
1.53
22.12
1.3
1.3
693.17
500.34
titre
1.40
164
1066
3285
29215
1.35
22.04
4.7
4.2
—
—
—
0
0
1725
13999
1.35
21.30
4.4
3.6
12.92
8.61
mg/mmol
2.78
1096
8599
1252
9665
1.39
21.14
2.9
2.7
4.50
5.43
e6/l
2.43
1119
8640
1642
13250
1.35
20.97
4.8
4.3
—
—
—
0
0
1637
13213
1.35
20.84
3.7
3.1
478.11
343.24
mg/l
0.50
1047
8219
1495
11904
1.36
20.77
2.6
2.3
3.06
3.09
mg/l
0.13
1244
10041
1288
10080
1.37
19.78
1.9
1.8
1209.84
1168.95
nmol/l
0.79
921
7496
1701
13897
1.34
19.70
4.8
3.9
7.40
7.40
ph
0.16
354
2587
1204
9328
1.38
19.67
3.2
3.0
514.13
537.70
mosm/kgh2o
3.78
1031
7968
1709
13992
1.33
19.44
5.5
5.4
5.08
4.19
ug/l
0.19
1513
12384
907
6718
1.43
19.21
3.1
2.4
2.22
2.28
g/l
2.00
816
6153
1652
13506
1.33
18.83
3.6
3.0
6.71
7.02
mmol/l
2.53
1319
11096
994
7523
1.40
18.54
1.3
1.2
1.50
1.65
u/ml
0.17
240
1869
1322
10490
1.35
18.34
6.6
6.5
—
—
—
0
0
1548
12579
1.33
18.28
3.7
3.3
0.44
0.50
e6/l
0.51
1221
9657
634
4431
1.49
18.13
2.6
2.4
5.61
6.71
ug/l
1.44
534
3745
1401
11250
1.34
17.87
5.0
4.5
0.00
0.00
estimate
0.69
456
3581
961
7287
1.39
17.62
3.1
2.4
11.61
12.15
umol/l
1.63
875
6712
1379
11086
1.33
17.35
3.0
2.8
4596.79
5947.23
umol/l
0.55
1169
9393
1314
10494
1.34
17.28
4.4
3.8
—
—
—
0
0
932
7057
1.39
17.19
2.0
2.0
29.97
30.01
s
0.07
907
6836
1484
12087
1.32
16.97
3.7
3.3
—
—
—
0
0
516
3508
1.52
16.79
4.5
4.4
—
—
—
0
0
1273
10195
1.33
16.26
1.8
1.7
13840191.53
26643700.08
pmol/l
0.60
961
8261
846
6357
1.40
16.25
3.1
2.5
21.31
21.58
%
0.21
717
5332
777
5776
1.41
15.86
1.3
1.2
—
—
—
0
0
46
121
3.83
15.52
33.9
25.5
105.55
112.33
ug/l
0.30
40
98
1833
15513
1.28
15.34
3.7
3.5
—
—
—
0
0
858
6543
1.37
14.96
1.5
1.5
2.65
2.58
g/l
0.35
459
3669
1651
13824
1.29
14.94
2.8
2.5
—
—
—
0
0
1487
12286
1.30
14.90
3.4
3.2
36.90
37.99
u/l
0.15
1398
11560
1135
9096
1.32
14.12
3.0
3.1
2.46
2.47
mmol/l
0.88
995
7894
671
4956
1.41
14.11
2.1
1.8
—
—
—
0
0
817
6241
1.37
14.02
1.3
1.3
45.92
38.53
iu/ml
0.64
244
1964
782
5945
1.37
13.81
7.1
5.0
1.07
1.03
mmol/l
3.11
713
5452
754
5706
1.38
13.69
2.6
2.3
1.79
1.78
%
0.17
635
5009
519
3705
1.45
13.15
4.2
3.3
105.76
92.29
ng/l
1.90
419
3096
1096
8827
1.31
13.01
1.8
1.7
1.49
1.43
mg/l
0.20
851
6865
569
4153
1.42
12.75
2.5
2.5
66.13
66.00
g/l
0.15
515
3692
1276
10527
1.28
12.53
1.7
1.6
1.33
1.33
mmol/l
0.01
1004
8742
802
6208
1.35
12.52
2.3
1.9
—
—
—
0
0
215
1269
1.72
12.49
1.4
1.4
263.63
272.00
ug/g
0.24
131
765
2227
19641
1.24
12.17
2.9
2.6
—
—
—
0
0
597
4429
1.39
12.15
4.4
3.4
1.77
2.01
mmol/l
0.90
507
3754
765
5915
1.35
12.00
1.3
1.2
13.02
14.59
u/ml
0.20
232
2090
397
2739
1.49
11.97
2.8
2.7
10.89
10.48
g/l
0.70
354
2479
506
3673
1.42
11.67
3.7
2.9
4.62
4.44
kpa
1.03
485
3555
593
4453
1.38
11.18
4.4
3.4
5.74
5.83
kpa
1.46
572
4326
193
1142
1.72
11.15
1.3
1.4
5.34
20.06
iu/ml
—
5
24
178
1031
1.75
11.09
2.1
1.5
0.23
0.24
g/l
0.95
168
961
635
4836
1.36
10.95
4.9
4.3
—
—
—
0
0
182
1065
1.74
10.94
2.1
1.5
1.17
1.17
g/l
0.04
171
989
61
236
2.60
10.92
1.1
1.1
—
—
—
0
0
1319
11080
1.26
10.90
3.7
3.2
—
—
—
0
0
531
3939
1.39
10.78
4.3
3.8
1.22
1.23
mmol/l
1.74
453
3437
526
3901
1.39
10.69
4.0
3.6
—
—
—
0
0
345
2375
1.49
10.53
2.4
2.4
43.03
24.40
au/ml
0.67
12
130
436
3140
1.42
10.50
1.8
1.5
—
—
—
0
0
1205
10058
1.26
10.45
4.6
4.0
—
—
—
0
0
604
4598
1.36
10.42
4.3
3.5
7.38
7.38
ph
—
6
35
342
2362
1.48
10.27
1.7
1.6
1.60
1.58
g/l
0.10
291
2011
542
4069
1.37
10.21
2.2
2.0
136.04
152.18
ug/g
0.39
392
3163
477
3510
1.40
10.15
2.2
2.3
—
—
—
0
0
35
103
3.41
10.12
1.9
1.4
—
—
—
0
0
482
3556
1.39
10.10
2.0
2.2
390.17
377.04
nmol/l
0.54
432
3220
173
1026
1.71
9.95
2.5
2.1
152.28
94.88
ug/min
0.64
90
575
165
969
1.73
9.83
1.8
1.8
11.32
12.01
mg/l
0.40
154
882
59
237
2.51
9.82
2.1
2.3
—
—
—
0
0
903
7339
1.28
9.69
3.2
2.9
0.82
0.81
mmol/l
0.64
824
6772
950
7776
1.27
9.61
3.3
2.9
1.09
1.65
e6/l
0.87
586
4480
407
2946
1.41
9.53
4.0
3.5
5.07
5.17
kpa
1.72
375
2757
350
2469
1.45
9.44
3.0
2.8
0.33
0.32
e6/l
0.04
342
2423
98
495
2.00
9.41
1.2
1.2
271.58
273.96
u/ml
0.03
60
293
401
2904
1.41
9.36
4.0
3.5
7.42
7.42
ph
0.17
57
374
163
969
1.70
9.31
1.2
1.2
29.60
33.93
u/ml
0.10
16
52
596
4609
1.33
9.23
1.5
1.4
—
—
—
0
0
56
227
2.48
9.17
1.1
1.1
—
—
—
0
0
308
2134
1.47
9.12
1.3
1.3
49.51
59.89
au/ml
0.34
14
117
311
2166
1.46
8.97
2.1
1.9
1.53
1.39
g/l
0.25
283
1938
32
98
3.28
8.74
34.5
27.4
7.17
7.09
ug/l
0.06
27
84
169
1033
1.66
8.72
3.6
2.5
1.95
1.67
mg/l
2.52
146
922
1310
11236
1.22
8.59
4.7
4.7
22.51
22.11
%
0.46
738
5863
559
4341
1.32
8.39
2.8
2.4
69.76
67.91
e9/l
0.53
420
3280
1231
10519
1.22
8.33
2.6
2.4
—
—
—
0
0
536
4142
1.33
8.32
9.3
6.0
12.38
10.85
mmol/l
4.26
509
3907
126
723
1.76
8.21
1.2
1.2
—
—
—
0
0
1255
10768
1.22
8.13
4.4
3.9
86.66
85.92
%
0.45
1234
10493
877
7254
1.25
8.00
3.5
3.1
2.94
2.66
e6/l
0.39
513
3995
149
903
1.67
7.98
1.2
1.2
2.58
3.43
u/ml
0.28
21
93
190
1226
1.57
7.90
4.9
4.3
7.41
7.42
ph
1.32
169
1121
231
1559
1.50
7.83
3.5
2.7
0.45
0.28
g/l
1.61
100
583
149
913
1.65
7.67
1.2
1.2
3.19
6.83
u/ml
1.21
29
150
104
577
1.82
7.61
1.5
1.3
—
—
—
0
0
135
808
1.69
7.60
3.9
3.6
59.02
58.44
%
0.24
135
808
450
3448
1.33
7.41
1.7
1.5
—
—
—
0
0
25
74
3.39
7.23
1.0
1.0
—
—
—
0
0
166
1061
1.58
7.22
4.6
4.5
2.52
2.78
mmol/l
0.55
119
729
166
1061
1.58
7.22
4.6
4.5
5.06
5.01
kpa
0.34
159
1043
287
2055
1.42
7.19
1.3
1.3
—
—
—
0
0
91
495
1.85
7.12
3.2
2.4
—
—
—
0
0
282
2018
1.42
7.09
1.5
1.3
—
—
—
0
0
166
1067
1.57
7.06
4.6
4.5
8.42
8.34
kpa
0.25
159
1048
943
7962
1.23
7.04
3.3
3.2
0.79
0.82
ug/l
0.44
701
5663
165
1063
1.57
6.95
1.6
1.7
—
—
—
0
0
498
3906
1.30
6.95
1.8
1.5
—
—
—
0
0
24
72
3.34
6.82
1.2
1.1
—
—
—
0
0
1074
9214
1.21
6.81
4.5
4.0
525.78
465.16
ng/l
0.09
903
7880
521
4129
1.29
6.72
5.5
6.0
1.33
1.38
mmol/l
0.63
502
4011
328
2431
1.37
6.72
3.8
3.2
25.14
25.24
mmol/l
0.22
315
2368
164
1066
1.56
6.66
3.8
3.7
—
—
—
0
0
201
1366
1.49
6.64
1.3
1.2
2.94
1.04
u/ml
0.54
19
136
1071
9209
1.21
6.61
5.3
4.7
1.02
1.02
kg/l
0.61
181
1427
282
2047
1.40
6.55
1.9
1.9
1.87
2.23
ug/l
0.25
242
1770
666
5467
1.25
6.43
5.4
4.7
33.70
33.51
%
0.17
439
3532
283
2070
1.39
6.30
4.3
3.7
—
—
—
0
0
487
3861
1.29
6.27
7.2
7.2
—
—
—
0
0
290
2135
1.38
6.21
4.8
3.6
24.01
24.24
mmol/l
0.58
284
2085
347
2632
1.34
6.14
3.2
3.4
6.50
5.58
e9/l
0.24
239
1976
111
671
1.67
6.10
1.3
1.2
25.64
49.21
u/ml
0.95
15
72
130
818
1.60
6.10
1.0
1.1
—
—
—
0
0
356
2725
1.33
5.93
1.2
1.2
—
—
—
0
0
156
1035
1.52
5.82
2.4
2.5
15.48
15.85
%
0.50
79
542
482
3865
1.27
5.67
2.4
2.4
34.80
50.19
u/l
0.65
405
3292
341
2612
1.33
5.67
2.7
2.5
—
—
—
0
0
665
5534
1.23
5.65
1.3
1.3
—
—
—
0
0
243
1768
1.39
5.62
4.7
3.9
24.52
25.06
mmol/l
1.99
217
1588
289
2166
1.35
5.56
3.4
3.1
4.26
4.37
pmol/l
1.10
249
1863
180
1244
1.46
5.53
1.4
1.4
—
—
—
0
0
75
419
1.80
5.48
2.6
2.2
2.73
1.70
u/field
0.72
26
138
171
1173
1.47
5.46
1.3
1.2
—
—
—
0
0
197
1395
1.43
5.33
2.0
1.9
21.88
21.62
s
0.16
178
1260
160
1089
1.48
5.32
2.4
2.4
3.77
3.63
g/l
0.49
152
1032
566
4664
1.24
5.27
2.9
2.6
9.49
9.42
umol/l
0.02
487
4031
87
514
1.70
5.26
2.0
2.3
1.49
1.24
g/24h
0.29
42
238
265
1978
1.36
5.25
2.2
2.3
7.49
7.51
g/l
0.07
233
1740
86
507
1.71
5.24
1.6
1.3
108.31
119.81
u/ml
0.42
13
105
342
2652
1.31
5.23
6.0
6.6
24.99
24.91
mmol/l
0.16
335
2633
264
1973
1.36
5.20
2.2
2.3
3.59
3.64
g/l
0.30
233
1740
20
64
3.13
5.18
2.1
1.8
9.96
9.12
mg/l
0.21
12
52
137
914
1.51
5.04
2.6
2.7
—
—
—
0
0
21
71
2.97
4.98
7.4
4.9
—
—
—
0
0
248
1851
1.36
4.94
2.2
2.3
9.94
10.11
g/l
0.26
215
1600
96
593
1.63
4.93
6.7
6.1
11.79
12.43
mg/l
0.81
90
536
376
2979
1.28
4.90
1.6
1.4
—
—
—
0
0
372
2945
1.28
4.88
3.7
3.0
129.08
127.25
g/l
0.85
363
2873
50
256
1.96
4.81
9.0
13.7
—
—
—
0
0
88
536
1.65
4.79
1.4
1.1
—
—
—
0
0
19
62
3.07
4.78
1.0
1.0
—
—
—
0
0
404
3243
1.27
4.74
4.0
3.9
0.06
0.36
%
1.31
128
949
152
1051
1.46
4.71
2.8
2.8
7.84
7.82
kpa
0.05
145
1023
79
470
1.69
4.70
1.3
1.2
—
—
—
0
0
410
3301
1.26
4.69
3.9
3.7
0.57
0.71
%
0.89
145
1135
426
3448
1.26
4.66
4.0
3.9
0.08
0.11
%
0.50
149
1143
135
916
1.49
4.61
1.2
1.2
93.08
96.29
titre
0.05
13
70
81
495
1.65
4.38
1.0
1.1
—
—
—
0
0
133
911
1.47
4.36
1.4
1.3
59.81
61.87
mmol/l
0.26
113
717
443
3631
1.24
4.35
4.0
3.8
0.92
0.94
%
0.04
164
1320
297
2325
1.29
4.28
2.1
2.1
12.47
11.67
nmol/l
0.76
262
2016
14
41
3.42
4.18
1.6
1.7
3.41
3.02
mmol/l
—
7
32
20
73
2.75
4.18
3.7
2.8
5.87
7.50
mg/l
0.82
13
56
539
4531
1.21
4.15
1.4
1.3
—
—
—
0
0
31
142
2.19
4.04
1.7
1.5
—
—
—
0
0
250
1929
1.31
4.03
1.3
1.3
298.48
229.38
u/ml
0.24
229
1748
61
354
1.73
4.02
2.5
2.0
627.49
643.56
ml
0.15
43
219
476
3971
1.22
3.97
1.4
1.4
—
—
—
0
0
253
1960
1.31
3.97
5.0
4.4
—
—
—
0
0
170
1241
1.38
3.96
3.1
2.9
24.69
24.99
mmol/l
0.39
162
1214
105
703
1.50
3.89
2.5
2.4
—
—
—
0
0
153
1103
1.40
3.85
2.1
2.2
125.91
126.16
g/l
0.04
114
801
61
359
1.71
3.84
2.5
1.2
30.80
27.15
iu/ml
—
5
13
59
344
1.72
3.84
1.8
2.0
0.94
1.13
e9/l
1.45
53
310
106
713
1.50
3.84
1.4
1.3
—
—
—
0
0
237
1829
1.31
3.83
2.2
2.4
2.94
3.00
g/l
0.31
205
1595
80
506
1.59
3.82
1.5
1.5
0.68
0.84
g/l
0.50
58
380
27
121
2.24
3.73
1.1
1.2
—
—
—
0
0
3313
31777
1.12
3.70
27.1
22.1
330.88
331.12
g/l
0.84
3291
31437
72
450
1.61
3.63
1.3
1.2
5.30
5.28
u/ml
0.00
37
195
39
204
1.92
3.61
1.2
1.1
55.98
40.75
mg/l
1.17
31
173
99
667
1.49
3.59
1.3
1.3
—
—
—
0
0
117
816
1.44
3.56
1.6
1.5
—
—
—
0
0
109
750
1.46
3.56
2.5
2.1
—
—
—
0
0
128
908
1.42
3.56
1.3
1.2
536.63
568.80
mg/l
0.37
123
857
174
1302
1.35
3.51
1.5
1.6
—
—
—
0
0
74
470
1.58
3.50
1.1
1.1
1.50
1.55
g/l
0.50
69
416
248
1952
1.28
3.49
1.3
1.2
—
—
—
0
0
44
244
1.81
3.43
2.2
1.9
510.25
490.75
min
0.49
32
174
37
194
1.91
3.42
1.1
1.1
—
—
—
0
0
14
48
2.92
3.29
1.2
1.2
109.07
104.01
ng/l
—
9
32
93
634
1.48
3.22
2.3
2.1
27.03
26.00
mg/l
0.07
23
142
149
1106
1.36
3.20
1.6
1.6
9558.99
14794.44
e6/l
1.84
117
785
113
804
1.41
3.13
3.1
3.5
1.43
1.69
%
0.31
98
693
39
215
1.82
3.13
2.0
2.0
0.17
0.21
e9/l
0.82
33
189
98
681
1.45
3.09
2.6
1.4
0.83
0.83
nmol/l
0.02
79
561
83
559
1.49
3.07
1.5
1.6
—
—
—
0
0
40
224
1.79
3.06
2.0
2.0
425.76
526.52
e6/l
0.61
34
189
198
1543
1.29
3.05
2.2
2.2
37.58
37.20
g/l
0.39
167
1306
117
842
1.40
3.05
2.9
2.4
30.40
34.53
umol/l
1.43
107
745
110
784
1.41
3.03
1.4
1.4
8.87
28.73
e6/l
1.59
84
609
110
785
1.41
3.01
1.5
1.4
997.37
1143.09
e6/l
0.08
92
646
181
1399
1.30
2.97
5.4
4.6
—
—
—
0
0
33
176
1.88
2.94
1.4
1.5
1.97
3.20
%
0.51
27
151
102
722
1.42
2.93
1.9
1.8
4.29
4.70
mmol/24h
0.59
86
606
77
516
1.50
2.93
1.3
1.3
—
—
—
0
0
45
265
1.70
2.91
1.0
1.0
—
—
—
0
0
119
868
1.38
2.88
2.1
1.7
5.94
4.09
iu/l
0.89
33
262
601
5280
1.16
2.80
3.5
3.9
26.65
20.37
ug/l
0.18
482
4376
58
369
1.58
2.80
1.4
1.4
—
—
—
0
0
14
53
2.65
2.79
2.9
2.8
0.36
0.47
u/field
0.21
14
53
487
4217
1.17
2.74
2.3
2.1
0.21
0.20
g/l
0.55
443
3904
636
5624
1.15
2.71
5.9
6.3
1.07
1.23
mmol/l
0.51
508
4411
140
1063
1.33
2.65
1.3
1.2
—
—
—
0
0
78
538
1.46
2.61
1.4
1.2
—
—
—
0
0
387
3303
1.19
2.60
1.6
1.5
—
—
—
0
0
20
93
2.16
2.60
6.8
6.6
—
—
—
0
0
101
735
1.38
2.53
1.5
1.5
29.62
31.32
g/l
0.78
91
651
1084
9955
1.11
2.50
1.3
1.3
—
—
—
0
0
81
570
1.43
2.46
9.6
6.3
7.73
7.29
mmol/l
0.48
67
465
143
1103
1.31
2.45
1.5
1.5
—
—
—
0
0
98
714
1.38
2.44
1.5
1.4
—
—
—
0
0
95
691
1.38
2.40
2.9
2.7
—
—
—
0
0
78
548
1.43
2.40
1.5
1.5
—
—
—
0
0
5
8
6.25
2.37
7.4
5.0
600.60
334.00
umol/l
—
5
8
182
1455
1.26
2.36
1.1
1.1
151.00
232.96
titre
—
5
24
632
5642
1.14
2.36
6.0
6.3
5.02
5.08
kpa
1.07
603
5358
631
5640
1.14
2.31
5.9
6.3
11.69
11.98
kpa
0.75
606
5349
40
245
1.64
2.30
1.3
1.1
—
—
—
0
0
72
503
1.44
2.30
1.3
1.3
—
—
—
0
0
103
767
1.35
2.27
4.3
2.9
—
—
—
0
0
163
1294
1.27
2.26
1.5
1.4
—
—
—
0
0
64
439
1.46
2.25
1.4
1.2
313.92
329.56
nmol/l
0.27
50
341
213
1744
1.23
2.25
3.9
3.6
1.36
1.40
mmol/l
0.24
207
1713
66
456
1.45
2.24
1.3
1.3
276.09
276.56
mosm/kgh2o
0.04
53
334
49
318
1.55
2.23
1.4
1.3
7.68
6.99
g/l
0.70
37
222
49
318
1.55
2.23
1.4
1.3
0.41
0.43
g/l
0.12
38
223
49
318
1.55
2.23
1.4
1.3
2.72
2.88
g/l
0.29
37
224
28
157
1.79
2.21
2.4
2.5
—
—
—
0
0
237
1967
1.21
2.20
2.9
2.8
—
—
—
0
0
565
5038
1.14
2.16
6.1
6.5
94.75
95.41
%
1.07
549
4826
65
452
1.44
2.15
1.4
1.3
94515.18
133787.06
e6/l
0.23
45
308
39
243
1.61
2.12
1.3
1.5
13.87
13.76
umol/l
0.03
33
228
527
4685
1.14
2.11
3.2
3.0
243.61
228.40
ng/l
0.34
484
4289
81
588
1.38
2.11
1.4
1.4
13.04
11.35
u/l
0.34
64
479
42
267
1.58
2.11
1.5
1.9
16.62
16.19
%
0.08
42
256
44
283
1.56
2.10
2.2
2.5
7.42
7.43
ph
0.27
21
107
34
205
1.66
2.10
1.1
1.1
—
—
—
0
0
8
25
3.20
2.09
1.1
1.2
—
—
—
0
0
8
25
3.20
2.09
1.1
1.2
—
—
—
0
0
62
431
1.44
2.06
1.4
1.5
27.59
28.30
%
0.04
33
270
24
132
1.82
2.03
1.2
1.2
—
—
—
0
0
206
1702
1.22
2.03
2.4
3.2
66.52
93.66
mg/l
0.37
156
1384
62
433
1.44
2.02
1.4
1.2
36.58
48.91
u/ml
—
10
30
33
200
1.65
2.01
1.3
1.5
68.94
66.84
%
0.13
26
167
38
239
1.59
2.01
2.3
1.9
4.48
2.79
u/field
0.46
29
160
49
327
1.50
2.00
3.3
3.0
—
—
—
0
0
117
1494
0.78
1.96
1.3
1.4
—
—
—
0
0
16
77
2.08
1.96
1.7
1.6
—
—
—
0
0
383
3350
1.15
1.96
4.2
4.3
—
—
—
0
0
72
522
1.38
1.92
1.1
1.0
—
—
—
0
0
48
323
1.49
1.90
1.4
1.3
—
—
—
0
0
42
275
1.53
1.89
1.5
1.9
74.55
72.20
%
0.47
42
256
199
1653
1.21
1.88
2.4
3.1
4.50
3.19
ratio
0.22
19
122
204
1701
1.21
1.86
2.4
3.2
40.62
51.87
mg/l
0.64
155
1382
172
1410
1.23
1.85
2.8
3.5
—
—
—
0
0
60
425
1.42
1.84
1.1
1.1
—
—
—
0
0
157
1276
1.24
1.83
2.5
3.3
—
—
—
0
0
71
519
1.37
1.82
1.3
1.4
37.30
60.70
mu/l
1.01
62
458
19
101
1.88
1.80
2.6
2.2
7.59
7.66
mmol/l
0.03
14
60
289
2497
1.17
1.76
4.7
3.8
—
—
—
0
0
127
1015
1.26
1.74
3.1
3.1
304.86
821.77
u/ml
0.98
119
930
43
289
1.49
1.74
1.3
1.3
—
—
—
0
0
19
103
1.85
1.71
1.2
1.2
—
—
—
0
0
357
3142
1.15
1.71
6.8
6.3
24.67
24.66
mmol/l
0.03
343
2992
21
118
1.78
1.70
2.8
2.0
—
—
—
0
0
311
2712
1.16
1.69
1.2
1.2
—
—
—
0
0
162
1336
1.22
1.68
3.2
3.2
0.77
0.81
nmol/l
0.70
120
1013
80
606
1.33
1.66
1.5
1.7
348.35
308.57
mu/l
0.30
72
557
17
90
1.89
1.65
2.2
2.1
2.83
3.31
ug/l
—
8
33
20
112
1.79
1.64
1.4
1.5
65.83
142.56
nmol/24h
0.73
20
112
10
42
2.38
1.61
2.6
5.9
7.78
8.10
mmol/l
—
5
29
131
1062
1.24
1.61
1.1
1.1
—
—
—
0
0
36
238
1.52
1.59
1.2
1.4
—
—
—
0
0
14
70
2.00
1.59
1.6
1.7
81.25
225.86
e6/l
—
8
29
126
1024
1.24
1.52
3.8
3.7
26.86
30.08
mg/l
0.47
81
664
42
290
1.45
1.52
1.8
2.5
7.58
6.95
mmol/l
0.62
33
197
34
225
1.51
1.51
1.6
1.5
0.19
0.24
nmol/l
0.49
25
169
114
918
1.25
1.50
3.5
2.4
—
—
—
0
0
118
954
1.24
1.50
1.2
1.2
—
—
—
0
0
335
2968
1.14
1.49
3.9
3.4
—
—
—
0
0
20
116
1.73
1.48
1.4
1.8
32.05
31.06
%
0.11
20
105
76
583
1.31
1.47
1.6
1.4
28417.32
60718.54
e6/l
1.29
47
346
16
87
1.84
1.45
1.4
1.5
7.25
8.61
%
—
8
46
74
568
1.31
1.44
1.5
1.5
59.32
62.85
%
0.30
43
355
13
66
1.97
1.43
1.0
1.1
—
—
—
0
0
37
254
1.46
1.40
1.9
1.3
—
—
—
0
0
64
484
1.33
1.39
1.2
1.3
261.96
302.47
pmol/l
0.62
57
410
28
182
1.54
1.37
1.1
4.9
72.55
72.11
mg/l
0.01
20
126
38
264
1.44
1.36
1.3
1.4
—
—
—
0
0
33
225
1.47
1.30
1.6
1.8
—
—
—
0
0
66
511
1.30
1.24
3.7
4.2
—
—
—
0
0
49
364
1.35
1.22
1.1
1.1
—
—
—
0
0
21
132
1.59
1.20
1.1
1.2
—
0.49
—
0
10
21
132
1.59
1.20
1.3
1.2
115.62
154.72
mmol/24h
1.93
21
132
6
26
2.31
1.18
1.0
1.1
—
3.50
—
0
5
8
38
2.11
1.18
1.1
1.1
—
—
—
0
0
16
94
1.70
1.17
1.8
1.5
127.23
134.57
ng/l
0.08
16
94
31
215
1.44
1.15
4.5
6.5
—
—
—
0
0
8
39
2.05
1.15
1.3
1.4
—
—
—
0
0
41
301
1.37
1.12
3.7
2.5
—
—
—
0
0
63
493
1.28
1.12
1.0
1.1
16.52
1813.73
iu/ml
0.71
13
94
233
2062
1.14
1.11
1.2
1.2
102.19
134.05
iu/ml
0.68
63
718
38
276
1.38
1.11
1.2
1.1
—
—
—
0
0
35
251
1.40
1.10
1.7
1.6
93.14
88.45
umol/l
0.15
35
251
280
2510
1.12
1.09
7.2
8.1
24.21
24.42
mmol/l
0.65
267
2405
497
4589
1.09
1.09
6.8
7.0
118.16
119.97
g/l
1.24
486
4459
79
638
1.24
1.09
1.6
1.5
966.71
1971.49
e6/l
3.19
56
457
33
235
1.41
1.08
1.2
1.4
1.43
1.09
promille
0.64
25
184
61
479
1.28
1.06
2.5
2.0
—
—
—
0
0
78
631
1.24
1.06
1.2
1.3
39.48
31.79
iu/l
1.08
58
531
17
105
1.62
1.05
1.2
1.2
205.92
122.32
nmol/l
0.71
12
73
7
33
2.12
1.05
1.0
1.1
—
—
—
0
0
15
90
1.67
1.03
1.0
1.0
—
—
—
0
0
35
255
1.38
1.02
1.2
1.3
—
—
—
0
0
9
47
1.92
1.02
1.2
1.5
49.22
45.17
umol/l
—
9
47
38
281
1.35
1.01
1.3
1.2
2.07
2.15
mmol/l
0.26
38
262
5
108
0.46
1.00
1.0
1.4
—
—
—
0
0
15
91
1.65
1.00
1.3
1.3
—
—
—
0
0
21
139
1.51
1.00
1.3
2.2
47.09
120.36
umol/l
1.58
11
77
65
520
1.25
0.99
1.4
2.0
—
—
—
0
0
31
223
1.39
0.98
1.6
1.4
2.00
3.64
%
—
7
53
0
30
0.00
0.97
0.0
1.1
—
—
—
0
0
7
36
1.95
0.97
1.0
1.0
—
—
—
0
0
7
36
1.95
0.97
1.0
1.0
—
—
—
0
0
7
36
1.95
0.97
1.0
1.0
—
—
—
0
0
37
275
1.35
0.97
1.9
1.6
—
—
—
0
0
41
310
1.33
0.96
1.0
1.0
324.63
308.57
ng/l
0.15
24
198
33
241
1.37
0.96
1.0
1.0
0.20
1.20
u/ml
2.18
16
127
41
312
1.32
0.93
1.0
1.0
654.72
704.25
ng/l
0.37
25
192
9
52
1.73
0.92
9.1
12.9
5.52
5.27
mmol/l
—
9
52
27
192
1.41
0.92
1.2
1.0
—
—
—
0
0
14
87
1.61
0.87
1.0
1.0
—
—
—
0
0
13
80
1.63
0.84
1.0
1.2
—
—
—
0
0
39
300
1.30
0.84
1.0
1.1
2.31
3.55
u/ml
0.36
19
139
43
337
1.28
0.81
1.8
2.0
1.48
2.05
ug/l
1.37
33
283
64
526
1.22
0.81
1.3
1.3
—
—
—
0
0
22
155
1.42
0.81
1.6
2.0
—
—
—
0
0
114
988
1.16
0.80
1.1
1.1
—
—
—
0
0
40
312
1.28
0.79
1.0
1.1
—
—
—
0
0
42
331
1.27
0.77
1.5
1.5
—
—
—
0
0
6
34
1.77
0.76
4.2
1.9
—
—
—
0
0
40
314
1.28
0.76
1.0
1.1
—
—
—
0
0
14
91
1.54
0.75
1.4
1.5
—
—
—
0
0
13
83
1.57
0.74
1.0
1.1
—
—
—
0
0
40
315
1.27
0.74
1.4
1.2
—
—
—
0
0
27
201
1.35
0.74
2.5
1.7
9.48
9.77
umol/l
0.02
20
132
7
38
1.84
0.73
1.3
1.4
—
—
—
0
0
43
343
1.26
0.73
1.1
1.1
2.38
1.57
u/ml
0.23
22
178
5
26
1.92
0.70
1.0
1.0
—
—
—
0
0
5
26
1.92
0.70
1.0
1.0
—
—
—
0
0
228
2083
1.10
0.70
4.8
4.6
0.86
0.87
%
0.14
215
1957
49
399
1.23
0.70
1.2
1.2
—
—
—
0
0
41
327
1.26
0.70
1.2
1.3
1.49
1.55
nmol/l
0.13
34
291
21
153
1.37
0.67
1.0
1.0
—
—
—
0
0
50
411
1.22
0.66
1.2
1.2
—
—
—
0
0
104
1183
0.88
0.66
1.4
1.5
—
—
—
0
0
152
1689
0.90
0.66
1.3
1.3
—
—
—
0
0
105
923
1.14
0.64
1.7
1.7
—
—
—
0
0
22
163
1.35
0.64
1.6
2.0
6.14
8.35
%
0.47
22
155
97
849
1.15
0.64
1.6
1.5
—
—
—
0
0
8
129
0.62
0.63
1.4
1.1
—
—
—
0
0
23
172
1.34
0.63
3.7
2.6
—
—
—
0
0
21
155
1.36
0.62
1.1
1.3
—
—
—
0
0
12
79
1.52
0.62
1.5
1.1
—
—
—
0
0
15
104
1.44
0.62
1.1
1.1
0.54
0.45
u/ml
—
8
33
29
226
1.28
0.61
1.4
1.3
5.39
0.80
u/ml
0.80
20
130
60
508
1.18
0.60
1.3
1.2
157.73
215.30
miu/ml
0.51
11
179
59
500
1.18
0.59
1.1
1.3
—
—
nmol/l
—
0
0
36
291
1.24
0.58
1.0
1.1
1.14
1.20
u/ml
0.03
17
117
21
158
1.33
0.57
1.1
1.4
68.81
59.28
%
0.62
16
137
27
211
1.28
0.57
2.2
2.4
39.59
38.39
%
0.13
17
126
14
98
1.43
0.56
3.0
1.8
1.34
1.17
ug/l
0.07
14
90
60
513
1.17
0.55
4.6
4.5
314.16
346.55
umol/l
0.85
51
434
8
126
0.63
0.54
2.0
1.8
—
—
—
0
0
14
99
1.42
0.54
1.2
1.1
1292.64
1680.95
miu/ml
0.77
14
99
227
2107
1.08
0.53
4.8
4.6
1.57
1.58
%
0.05
217
1977
58
497
1.17
0.53
3.5
3.6
62.86
56.96
%
1.40
44
403
27
214
1.26
0.52
1.3
1.5
6.22
7.56
u/l
0.49
21
179
82
723
1.14
0.52
2.9
2.4
—
—
—
0
0
20
152
1.32
0.52
1.1
1.1
209.43
553.70
ng/l
—
7
34
23
179
1.29
0.51
1.2
1.1
147.78
138.61
nmol/l
0.27
23
179
82
726
1.13
0.49
1.7
1.5
—
—
—
0
0
206
1913
1.08
0.49
2.2
2.0
—
—
—
0
0
15
111
1.35
0.46
1.6
1.8
—
—
—
0
0
32
264
1.21
0.45
1.4
1.3
25.90
33.91
u/l
0.57
26
215
26
210
1.24
0.45
1.7
1.5
0.83
0.94
g/l
1.64
26
210
25
201
1.24
0.44
1.0
1.1
—
—
—
0
0
58
506
1.15
0.44
1.7
1.5
—
—
—
0
0
15
112
1.34
0.44
1.3
1.5
—
—
—
0
0
7
51
1.37
0.44
1.0
1.2
—
—
—
0
0
5
32
1.56
0.42
1.4
1.1
—
—
—
0
0
35
295
1.19
0.41
3.9
5.2
410.01
99.73
u/ml
—
8
90
42
488
0.86
0.41
1.3
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
19.03
—
0
9
0
16
0.00
0.41
0.0
1.4
—
207.50
—
0
8
14
105
1.33
0.41
1.9
1.3
—
—
—
0
0
15
114
1.32
0.40
2.0
2.1
—
—
—
0
0
10
138
0.72
0.40
1.5
1.4
—
—
—
0
0
5
35
1.43
0.39
1.2
1.1
—
—
—
0
0
18
142
1.27
0.38
1.9
1.6
—
—
—
0
0
47
411
1.14
0.37
1.1
1.2
—
—
—
0
0
9
70
1.29
0.36
1.0
1.1
—
—
—
0
0
10
135
0.74
0.36
1.5
1.4
—
—
—
0
0
11
81
1.36
0.36
1.2
1.3
—
190.22
—
0
18
9
71
1.27
0.36
1.2
1.2
—
—
—
0
0
12
90
1.33
0.35
1.0
1.1
—
—
—
0
0
13
99
1.31
0.35
1.1
1.1
0.64
0.68
umol/24h
—
6
48
10
134
0.75
0.34
1.5
1.4
—
—
—
0
0
28
236
1.19
0.34
2.5
2.2
67.33
124.79
ug/min
—
6
58
39
339
1.15
0.34
1.0
1.0
—
—
—
0
0
83
758
1.10
0.33
1.3
1.2
90.57
40.68
u/l
0.53
68
664
44
497
0.88
0.32
2.7
3.2
—
—
—
0
0
23
193
1.19
0.30
1.6
1.2
1.00
1.23
nmol/l
0.46
11
147
10
75
1.33
0.30
5.2
6.5
—
—
—
0
0
187
1773
1.06
0.30
2.8
3.1
1222.79
2115.79
u/ml
0.42
162
1504
7
56
1.25
0.29
1.3
1.5
—
—
—
0
0
102
1094
0.93
0.28
6.4
6.2
104.78
104.92
mmol/l
0.11
93
979
102
1094
0.93
0.28
6.4
6.2
11.34
11.23
mmol/l
0.14
93
979
8
62
1.29
0.28
5.9
7.0
—
—
—
0
0
20
236
0.85
0.26
1.1
1.1
—
—
—
0
0
55
500
1.10
0.26
1.2
1.3
—
—
—
0
0
10
77
1.30
0.26
1.6
1.5
—
—
—
0
0
15
123
1.22
0.25
1.1
1.1
—
—
—
0
0
9
75
1.20
0.25
1.9
4.2
49.56
67.27
u/l
—
9
70
45
407
1.11
0.24
3.5
2.9
45.51
28.12
mg/l
0.42
37
305
10
126
0.79
0.24
8.6
12.7
888.90
836.72
nmol/l
—
10
120
5
40
1.25
0.22
2.6
2.1
14.81
18.47
umol/l
—
5
40
30
267
1.12
0.21
1.7
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
3.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.01
—
0
7
18
154
1.17
0.21
1.8
2.1
486.17
8792.81
e6/l
0.83
12
111
0
13
0.00
0.21
0.0
1.0
—
0.30
—
0
6
30
268
1.12
0.20
1.6
1.9
—
—
—
0
0
6
48
1.25
0.20
1.0
1.2
1.86
1.79
umol/24h
—
6
48
27
241
1.12
0.19
1.4
1.6
—
—
—
0
0
21
184
1.14
0.19
1.0
1.1
0.04
2.53
u/ml
—
5
74
103
979
1.05
0.18
1.3
1.3
—
—
—
0
0
7
58
1.21
0.18
2.6
1.3
—
—
—
0
0
49
454
1.08
0.18
1.3
1.6
—
—
—
0
0
199
2059
0.97
0.18
4.0
4.1
79.76
77.73
u/ml
0.02
193
1964
49
528
0.93
0.18
1.4
1.6
—
—
—
0
0
7
62
1.13
0.17
1.0
1.2
3.39
532006.83
nmol/l
—
7
50
5
67
0.75
0.17
1.0
1.1
—
0.30
—
0
24
17
148
1.15
0.16
1.4
1.4
1.55
1.55
g/l
0.02
17
148
18
159
1.13
0.15
1.2
1.2
1.01
1.06
ratio
—
5
49
11
93
1.18
0.14
1.6
1.5
—
—
—
0
0
86
822
1.05
0.14
1.3
1.4
176.72
212.96
pmol/l
0.52
81
795
8
99
0.81
0.13
1.8
1.4
—
—
—
0
0
264
2580
1.02
0.13
8.5
8.5
—
—
—
0
0
38
354
1.07
0.13
1.5
2.0
4091.21
3453.58
u/l
0.08
14
136
36
386
0.93
0.12
1.9
1.8
—
—
—
0
0
16
142
1.13
0.12
2.3
1.8
—
—
—
0
0
29
268
1.08
0.12
2.7
2.6
—
—
—
0
0
113
1168
0.97
0.11
2.9
2.8
—
—
—
0
0
37
394
0.94
0.11
1.9
1.9
—
—
—
0
0
37
394
0.94
0.11
1.9
1.9
—
—
—
0
0
12
105
1.14
0.11
1.0
1.0
—
—
—
0
0
12
105
1.14
0.11
1.0
1.0
—
—
—
0
0
12
105
1.14
0.11
1.0
1.0
—
—
—
0
0
19
173
1.10
0.10
1.3
1.4
194.16
203.50
pmol/l
0.06
19
173
24
259
0.93
0.10
2.6
3.4
—
—
—
0
0
17
154
1.10
0.10
1.4
1.3
228.81
253.08
ug/l
—
9
80
37
392
0.94
0.10
1.9
1.9
—
—
—
0
0
155
1513
1.03
0.09
5.3
5.6
1.33
1.34
mmol/l
0.09
131
1348
32
340
0.94
0.09
4.3
1.6
11.50
10.73
%
0.48
32
340
12
134
0.90
0.08
1.2
1.3
—
—
—
0
0
7
64
1.09
0.08
3.3
2.3
—
—
—
0
0
23
216
1.07
0.06
3.8
4.0
—
—
—
0
0
25
236
1.06
0.06
1.1
1.1
0.10
12.44
nmol/l
—
7
58
15
138
1.09
0.06
1.7
1.9
12716.70
23815.05
e6/l
—
10
81
35
365
0.96
0.06
1.9
1.9
—
—
—
0
0
31
299
1.04
0.03
2.0
1.7
—
—
—
0
0
135
1363
0.99
0.02
15.8
10.9
—
—
—
0
0
17
163
1.04
0.01
1.1
1.1
33.11
40.06
g/l
—
8
77
95
941
1.01
0.01
1.2
1.2
—
—
—
0
0
21
203
1.03
0.01
1.0
1.1
1.21
2.33
u/ml
—
8
97
18
186
0.97
0.00
2.7
2.1
—
—
—
0
0
39
387
1.01
0.00
1.1
1.1
1.97
1.98
u/ml
—
7
119
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
41
410
1.00
-0.00
1.1
1.3
7.67
7.89
mmol/l
0.17
35
340
0
5
0.00
-0.00
0.0
1.6
—
2.47
—
0
5
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
200.96
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
91
0.99
-0.00
1.6
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
369
3690
1.00
-0.00
1.6
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint MACULA_NAS and mortality.

Females

Parameter HR [95% CI] p-value
MACULA_NAS 0.835 [0.77, 0.9] < 0.001
Birth year 0.996 [0.99, 1.0] 0.321

During the follow-up period (1.1.1998 — 31.12.2019), 5005 out of 18044 females with MACULA_NAS died.

Males

Parameter HR [95% CI] p-value
MACULA_NAS 0.831 [0.76, 0.91] < 0.001
Birth year 0.989 [0.98, 1.0] 0.015

During the follow-up period (1.1.1998 — 31.12.2019), 3981 out of 12716 males with MACULA_NAS died.

Mortality risk

Mortality risk for people of age

years, who have MACULA_NAS.

N-year risk Females Males
1 0.082% 0.134%
5 0.476% 0.925%
10 1.182% 2.498%
15 2.459% 4.884%
20 4.356% 8.585%

Relationships between endpoints

↥

Index endpoint: MACULA_NAS – Degenerative macular diseases

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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