≡ Risteys
R13

Documentation Changelog GitHub Contact & Feedback

Other and unspecified disorders of binocular movement

DOID Endpoint Browser PheWeb

H7_BINOCUMOVNAS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H51.8, H51.9
  • Hospital discharge: ICD-9 — 378[8-9]
  • Cause of death: ICD-10 — H51.8, H51.9
  • Cause of death: ICD-9 — 378[8-9]

2 out of 7 registries used, show all original rules.

211

4. Check minimum number of events

None

211

5. Include endpoints

None

211

6. Filter based on genotype QC (FinnGen only)

202

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1678 882 788
Only index persons 1432 767 665
Unadjusted period prevalence (%)
Whole population 0.02 0.03 0.02
Only index persons 0.03 0.03 0.03
Median age at first event (years)
Whole population 25.62 31.82 18.49
Only index persons 29.45 33.84 24.39

-FinnGen-

Key figures

All Female Male
Number of individuals 202 130 72
Unadjusted period prevalence (%) 0.04 0.05 0.03
Median age at first event (years) 40.36 37.69 45.17

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
211
Matched controls
2110
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H51.8
ICD-10 Finland
Other specified disorders of binocular movement
+∞
118.1
102
*
H51.9
ICD-10 Finland
Disorder of binocular movement, unspecified
+∞
89.0
79
*
H53.2
ICD-10 Finland
Diplopia
29.7
56.2
39
16
XCW99
NOMESCO Finland
Other investigative procedure of eye
7.5
30.7
51
86
3788X
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Other disorders of binocular eye movements
+∞
26.6
25
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.3
24.2
47
92
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
141.0
24.1
25
*
XA800
NOMESCO Finland
Neuropsychological investigation
7.7
22.9
35
53
H50.2
ICD-10 Finland
Vertical strabismus
+∞
21.2
20
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.2
19.4
46
107
H50.1
ICD-10 Finland
Divergent concomitant strabismus
+∞
19.0
18
*
H50.0
ICD-10 Finland
Convergent concomitant strabismus
+∞
18.0
17
*
H50.30
ICD-10 Finland
Intermittent esotropy
+∞
16.9
16
*
H50.31
ICD-10 Finland
Intermittent exotropia
+∞
15.8
15
*
R5110, ,
SPAT
7.1
15.8
25
39
H50.52
ICD-10 Finland
Exophoria
149.2
13.6
14
*
L28
ICPC
Limited function/disability (L)
3.6
12.0
47
157
XCK00
NOMESCO Finland
Perimetry
6.0
11.9
22
40
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
+∞
11.6
11
*
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
11.6
11
*
H50.8
ICD-10 Finland
Other specified strabismus
+∞
11.6
11
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.2
11.5
54
202
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.9
11.3
37
109
TAB00
NOMESCO Finland
Lumbar puncture
5.0
11.3
26
58
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
4.5
11.1
29
72
R4110
NOMESCO Finland
Physiotherapy
2.8
11.1
81
387
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.9
10.4
34
100
Z2445
NOMESCO Finland
Psychologist
4.2
9.6
27
71
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
10.8
9.2
17
17
A28
ICPC
Limited function/disability NOS
3.3
9.2
39
136
G35
ICD-10 Finland
Multiple sclerosis
16.5
9.2
14
9
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
9.2
85
449
AA1AD
NOMESCO Finland
CT of head and brain
2.7
9.0
61
276
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.8
8.7
28
81
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
28.8
8.6
11
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
8.4
8.6
18
23
CEC00
NOMESCO Finland
Recession of extraocular muscle
+∞
8.4
8
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
8.2
69
346
F83
ICD-10 Finland
Mixed specific developmental disorders
12.5
7.7
13
11
M03BX01
ATC
baclofen; systemic
10.6
7.7
14
14
N28
ICPC
Limited function/disability (N)
26.1
7.6
10
*
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
14.0
7.5
12
9
R4120
NOMESCO Finland
Occupational therapy
3.6
7.4
25
75
Z3231
NOMESCO Finland
Registered nurse
2.3
7.3
74
399
H47.7
ICD-10 Finland
Disorder of visual pathways, unspecified
+∞
7.3
7
*
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
7.3
7
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.5
7.3
26
81
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
31.2
7.2
9
*
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
20.9
7.2
10
5
Z3226
NOMESCO Finland
Physiotherapist
2.5
6.9
54
259
Z2446
NOMESCO Finland
Social worker
3.4
6.9
26
84
109
Kela drug reimbursment
Multiple sclerosis
17.4
6.8
10
6
L03AX13
ATC
glatiramer acetate; parenteral
41.4
6.8
8
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.3
6.8
27
90
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.3
6.7
26
85
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
23.4
6.7
9
*
P85
ICPC
Mental retardation
23.4
6.7
9
*
G91.1
ICD-10 Finland
Obstructive hydrocephalus
71.9
6.5
7
*
N99
ICPC
Neurological disease other
71.9
6.5
7
*
G91.0
ICD-10 Finland
Communicating hydrocephalus
71.9
6.5
7
*
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
+∞
6.3
6
*
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
+∞
6.3
6
*
0148, ,
NOMESCO Finland
+∞
6.3
6
*
3789X
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Unspecified disorder of eye movements
+∞
6.3
6
*
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
6.3
6
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
27.6
6.3
8
*
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
27.6
6.3
8
*
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.7
6.2
20
58
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.5
6.0
21
64
H53.1
ICD-10 Finland
Subjective visual disturbances
3.5
6.0
21
64

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
25
38
7.33
16.13
2.1
2.4
—
—
—
0
0
25
46
6.03
13.42
2.2
2.2
320.16
35.78
e6/l
0.46
19
36
25
46
6.03
13.42
2.1
2.0
58.32
2.34
e6/l
0.66
19
32
15
5
32.10
11.81
1.1
1.0
0.25
—
nmol/l
—
6
0
87
453
2.57
9.79
3.6
2.7
0.29
0.32
e6/l
0.11
66
318
104
593
2.49
9.59
5.2
3.5
60.55
57.74
e6/l
0.03
70
389
84
447
2.46
8.85
3.7
2.6
—
—
—
0
0
119
741
2.39
8.78
8.5
7.3
1.21
1.22
mmol/l
0.21
108
653
18
22
8.83
8.78
2.7
3.1
—
—
—
0
0
109
683
2.23
7.57
7.8
7.3
1.20
1.21
mmol/l
0.68
103
629
87
501
2.25
7.39
4.4
2.8
49.23
183.87
e6/l
0.49
66
367
14
17
8.73
6.94
2.7
2.8
—
—
—
0
0
17
40
4.53
6.89
1.2
1.1
—
—
—
0
0
61
319
2.28
6.39
4.1
2.6
601.75
568.44
mosm/kgh2o
0.49
56
263
129
903
2.10
6.33
8.4
6.2
0.04
0.04
e9/l
0.29
113
790
129
903
2.10
6.33
8.4
6.2
0.58
0.56
e9/l
0.31
113
792
122
840
2.07
6.22
8.3
6.6
—
—
—
0
0
131
928
2.09
6.16
6.2
5.4
6.36
6.48
mmol/l
0.27
122
851
131
932
2.07
6.03
9.3
6.6
0.19
0.19
e9/l
0.02
115
835
53
267
2.32
6.02
3.5
2.7
0.99
2.93
e6/l
1.94
26
141
130
929
2.04
5.84
8.5
6.2
2.11
2.04
e9/l
0.12
116
838
123
862
2.02
5.83
8.8
6.6
8.32
8.15
%
0.26
118
815
42
194
2.45
5.78
2.3
1.5
—
—
—
0
0
21
66
3.42
5.77
3.0
2.6
—
—
—
0
0
122
857
2.00
5.70
8.8
6.3
2.69
2.84
%
0.32
117
807
9
7
13.35
5.63
1.3
1.0
128.22
138.71
nmol/l
—
9
7
40
185
2.43
5.47
4.6
6.6
—
—
—
0
0
124
886
1.97
5.40
8.8
6.4
28.90
30.49
%
0.85
119
841
118
833
1.95
5.29
9.0
6.3
0.57
0.68
%
1.43
112
779
34
148
2.55
5.28
2.0
2.3
37.00
28.20
u/l
0.64
26
126
139
1043
1.97
5.13
12.7
8.7
3.81
4.04
e9/l
0.66
122
911
99
668
1.91
5.00
4.6
3.1
5.79
5.93
ph
—
7
58
10
13
8.01
4.91
1.7
1.5
—
—
—
0
0
8
8
10.33
4.56
1.0
1.6
11.61
10.88
umol/l
—
8
8
148
1160
1.92
4.50
5.3
3.8
—
—
—
0
0
22
83
2.84
4.48
4.2
7.6
130.68
129.40
g/l
0.10
22
83
33
153
2.37
4.47
9.0
10.0
0.59
1.00
mmol/l
0.28
25
121
8
9
9.18
4.31
1.1
1.3
1.69
1.67
mmol/l
—
8
9
83
554
1.82
4.16
1.9
1.8
97.05
93.89
pmol/l
0.21
46
285
59
355
1.92
4.08
5.5
4.1
—
—
—
0
0
41
217
2.10
4.04
1.8
1.6
901.09
1220.82
nmol/l
1.38
32
162
15
49
3.22
3.89
1.5
2.1
2.04
4.93
iu/l
—
5
19
111
823
1.74
3.78
4.7
3.3
0.00
0.00
estimate
-0.00
20
170
12
29
4.32
3.77
5.5
3.9
6.53
7.07
mmol/l
0.37
12
29
10
20
5.19
3.73
1.5
1.7
—
—
—
0
0
61
381
1.85
3.73
3.9
3.2
—
—
—
0
0
33
166
2.17
3.69
10.2
10.1
—
—
—
0
0
12
33
3.79
3.35
5.5
3.6
1.34
1.21
mmol/l
0.39
12
33
107
807
1.66
3.27
6.1
6.3
10.81
11.50
umol/l
0.26
102
765
108
818
1.66
3.23
7.2
4.7
0.00
0.00
estimate
-0.00
16
162
65
430
1.74
3.23
4.3
3.6
7.39
7.40
ph
—
10
67
67
451
1.71
3.12
3.7
2.6
—
—
—
0
0
157
1322
1.73
3.03
4.8
4.0
14.71
14.49
pmol/l
0.56
147
1222
75
524
1.67
3.03
2.4
2.2
—
—
—
0
0
39
225
1.90
3.01
1.8
2.0
—
—
—
0
0
8
17
4.85
2.95
5.8
7.1
—
—
—
0
0
15
58
2.71
2.94
1.6
1.7
—
—
—
0
0
27
138
2.10
2.91
12.2
10.5
24.77
24.95
mmol/l
0.08
27
138
68
470
1.66
2.83
8.8
7.0
—
—
—
0
0
12
39
3.20
2.82
6.9
5.6
—
—
—
0
0
107
831
1.58
2.75
4.9
3.3
0.00
0.00
estimate
-0.00
14
155
17
73
2.45
2.73
3.3
7.1
0.69
0.69
%
0.04
17
73
8
20
4.11
2.59
4.4
3.0
—
—
—
0
0
8
20
4.11
2.59
4.4
3.0
107.88
106.75
mmol/l
—
8
20
8
20
4.11
2.59
4.4
3.0
4.01
3.95
mmol/l
—
8
20
140
1168
1.59
2.57
2.8
3.0
34.90
40.53
u/l
0.42
133
1114
17
77
2.31
2.45
3.5
6.8
1.03
1.31
%
0.58
17
77
177
1579
1.75
2.34
24.9
15.0
332.86
333.35
g/l
0.27
177
1571
189
1721
1.94
2.31
20.8
12.9
3.92
3.94
mmol/l
0.35
184
1669
34
206
1.78
2.25
2.8
2.1
2.29
2.45
g/l
1.00
34
187
13
54
2.50
2.24
4.3
6.4
0.17
0.27
g/l
—
6
24
143
1218
1.54
2.23
7.9
6.4
87.39
81.67
u/l
0.37
135
1150
6
14
4.38
2.16
1.3
1.8
—
—
—
0
0
6
14
4.38
2.16
1.0
2.1
25.08
23.20
umol/l
—
6
14
33
201
1.76
2.15
1.3
1.3
—
—
—
0
0
6
16
3.83
1.95
1.3
1.1
—
—
nmol/l
—
0
0
6
16
3.83
1.95
1.3
1.1
—
—
—
0
0
103
838
1.45
1.90
11.2
9.1
0.00
0.00
e9/l
0.49
81
673
177
1605
1.64
1.88
5.6
4.6
1.65
1.86
mu/l
2.29
166
1483
5
12
4.24
1.83
1.2
1.1
—
—
—
0
0
61
453
1.49
1.78
1.5
1.4
2.21
2.07
g/l
0.14
32
254
6
18
3.40
1.76
1.3
1.1
—
—
nmol/l
—
0
0
15
75
2.08
1.74
10.4
14.0
—
—
—
0
0
8
30
2.73
1.74
1.3
1.1
—
—
—
0
0
11
48
2.36
1.73
1.9
2.5
—
—
—
0
0
78
616
1.42
1.64
11.9
10.9
1.36
1.23
inr
0.40
18
190
51
371
1.49
1.64
2.4
2.2
1.13
1.29
mg/l
0.17
41
281
34
227
1.59
1.59
2.9
2.1
12.79
14.24
umol/l
0.55
34
208
7
26
2.75
1.59
1.0
1.2
—
—
—
0
0
22
131
1.76
1.57
1.8
3.3
82.45
69.68
e9/l
0.57
13
94
196
1845
1.88
1.56
14.3
10.2
—
—
—
0
0
52
384
1.47
1.55
6.3
3.6
—
—
—
0
0
54
404
1.45
1.50
2.4
2.3
2.74
2.68
mg/l
0.06
49
341
7
28
2.55
1.46
1.4
1.3
—
—
—
0
0
18
103
1.82
1.46
6.9
6.0
—
—
—
0
0
5
16
3.17
1.44
1.2
1.3
—
—
—
0
0
7
29
2.46
1.40
1.7
13.4
60.77
66.94
%
—
7
29
13
68
1.97
1.36
6.9
4.0
—
—
—
0
0
22
138
1.66
1.32
10.8
10.6
97.12
96.10
%
0.90
22
132
167
1535
1.42
1.26
4.2
3.9
5.67
5.77
mmol/l
0.61
155
1414
8
36
2.27
1.25
1.0
1.3
—
—
—
0
0
192
1815
1.64
1.25
11.6
9.1
23.17
25.94
u/l
1.92
187
1754
123
1083
1.33
1.20
3.6
3.1
—
—
—
0
0
5
113
0.43
1.16
1.0
1.4
—
—
—
0
0
7
136
0.50
1.14
1.3
1.6
—
—
—
0
0
34
247
1.45
1.11
1.7
1.5
—
—
—
0
0
185
1748
1.47
1.05
19.7
11.6
23.43
21.34
mg/l
0.32
152
1326
5
22
2.30
1.04
3.0
2.6
63.20
60.41
%
—
5
22
7
134
0.51
1.02
1.3
1.6
—
—
—
0
0
7
135
0.50
1.02
1.3
1.5
—
—
—
0
0
7
135
0.50
1.02
1.3
1.6
—
—
—
0
0
19
124
1.58
1.01
1.4
1.4
—
—
—
0
0
27
192
1.47
0.98
1.4
1.2
—
—
—
0
0
5
23
2.20
0.98
3.0
2.6
—
—
—
0
0
22
150
1.52
0.97
1.8
1.5
—
—
—
0
0
26
185
1.46
0.95
1.2
1.2
—
—
—
0
0
7
127
0.54
0.91
1.3
1.6
—
—
—
0
0
13
79
1.69
0.90
1.3
1.2
—
—
—
0
0
6
31
1.96
0.85
2.0
13.2
—
—
—
0
0
39
306
1.34
0.83
1.7
1.7
—
—
—
0
0
16
106
1.55
0.81
1.5
1.4
23.98
25.79
iu/l
—
10
88
9
53
1.73
0.76
3.6
5.2
—
—
—
0
0
203
1978
1.69
0.76
28.4
17.5
39.27
40.20
%
1.30
195
1871
5
24
2.11
0.75
2.0
1.8
—
—
—
0
0
65
554
1.25
0.75
1.6
1.6
—
—
—
0
0
14
204
0.66
0.73
1.5
1.2
—
—
—
0
0
25
187
1.38
0.72
2.1
2.0
—
—
—
0
0
58
490
1.25
0.72
1.5
1.4
0.43
2.01
u/ml
2.19
14
118
19
136
1.44
0.69
7.4
5.8
4.94
5.06
kpa
0.46
19
130
26
199
1.35
0.66
1.3
1.2
—
—
—
0
0
8
130
0.60
0.66
1.6
1.4
—
—
—
0
0
38
308
1.29
0.66
3.2
3.5
81.91
228.86
ng/l
1.35
27
208
13
87
1.53
0.65
1.4
1.2
—
—
—
0
0
5
29
1.74
0.64
2.0
2.1
—
—
—
0
0
56
478
1.23
0.63
2.5
2.0
—
—
—
0
0
13
88
1.51
0.62
1.2
1.2
—
—
—
0
0
35
284
1.28
0.60
1.7
1.7
461.13
27459474.74
pmol/l
0.50
30
244
17
123
1.42
0.60
2.4
2.4
664.29
3550.26
u/l
—
7
50
6
37
1.64
0.56
1.2
1.1
—
—
—
0
0
12
82
1.49
0.55
1.7
1.4
3.05
9.00
u/l
—
7
63
17
126
1.38
0.53
1.4
2.1
14.74
11.33
nmol/l
0.67
17
119
11
75
1.49
0.52
2.4
4.6
—
—
—
0
0
20
156
1.31
0.47
1.4
1.3
—
—
—
0
0
24
194
1.27
0.44
1.4
3.0
15.99
6.09
umol/l
0.42
18
157
32
268
1.23
0.44
1.8
2.5
65.39
95.21
ug/g
0.63
25
208
15
113
1.35
0.44
2.6
4.4
—
—
—
0
0
5
31
1.63
0.43
1.2
2.0
—
—
—
0
0
5
32
1.58
0.42
1.0
1.1
—
—
—
0
0
53
469
1.17
0.42
5.2
2.9
—
—
—
0
0
5
33
1.53
0.41
1.0
1.1
—
—
—
0
0
57
508
1.17
0.41
5.1
3.2
15.23
44.34
ng/l
1.79
37
313
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
33
384
0.83
0.39
1.8
2.9
280.61
4748.64
umol/l
1.58
28
335
54
600
0.87
0.37
4.0
2.5
—
—
—
0
0
166
1605
1.16
0.35
4.1
3.8
4.60
4.63
mmol/l
0.13
160
1505
25
210
1.22
0.34
3.4
2.6
0.58
0.70
ug/l
0.65
19
134
159
1535
1.15
0.33
3.7
3.4
1.22
1.25
mmol/l
0.15
147
1422
44
393
1.15
0.31
3.0
3.6
17.15
11.86
mg/mmol
0.20
26
252
7
96
0.72
0.31
4.4
2.4
—
—
—
0
0
41
370
1.13
0.26
2.4
3.1
121.97
80.61
mg/l
0.24
23
246
69
643
1.11
0.26
1.9
2.0
—
—
—
0
0
16
133
1.22
0.25
3.9
3.0
—
—
—
0
0
9
77
1.18
0.24
2.1
1.4
—
—
—
0
0
9
77
1.18
0.24
2.1
1.4
—
—
—
0
0
5
39
1.29
0.23
1.4
2.3
—
—
—
0
0
40
365
1.12
0.21
5.4
3.3
1.01
1.02
kg/l
—
8
54
8
104
0.76
0.21
11.3
3.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
3.7
—
41.67
—
0
6
0
11
0.00
0.21
0.0
1.1
—
7.71
—
0
11
0
10
0.00
0.21
0.0
1.8
—
66.00
—
0
10
11
89
1.25
0.21
1.9
1.4
301.13
275.81
miu/ml
—
6
47
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
6
48
1.26
0.20
1.3
1.3
—
—
—
0
0
41
377
1.11
0.19
2.1
1.7
—
—
—
0
0
10
81
1.25
0.19
2.3
1.3
—
—
—
0
0
163
1595
1.10
0.19
4.0
3.8
1.46
1.46
mmol/l
0.05
155
1482
147
1433
1.09
0.18
5.4
4.8
38.03
38.82
mmol/mol
0.48
141
1344
7
61
1.15
0.17
1.0
1.2
—
—
—
0
0
5
67
0.74
0.17
2.4
2.0
—
—
—
0
0
8
69
1.17
0.16
1.1
1.1
—
—
—
0
0
9
80
1.13
0.15
2.1
1.5
—
—
—
0
0
32
295
1.10
0.15
1.3
1.3
30.44
31.77
iu/ml
—
7
93
9
83
1.09
0.15
1.2
1.9
—
—
—
0
0
31
290
1.08
0.11
1.3
1.6
—
—
—
0
0
31
290
1.08
0.11
1.1
1.3
0.99
10.10
u/ml
—
10
119
5
44
1.14
0.10
2.4
1.4
—
—
—
0
0
18
165
1.10
0.09
1.1
1.5
—
—
—
0
0
164
1620
1.06
0.09
4.5
4.2
2.80
2.75
mmol/l
0.28
157
1510
5
62
0.80
0.08
1.2
1.6
—
—
—
0
0
42
438
0.95
0.08
6.1
3.3
0.00
0.01
estimate
0.50
16
160
6
71
0.84
0.08
1.7
1.3
—
—
—
0
0
10
106
0.94
0.01
1.7
1.4
—
—
—
0
0
10
103
0.97
0.00
1.0
1.1
—
—
—
0
0
11
108
1.02
0.00
1.3
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
1.09
—
0
5
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
11.8
—
8.77
—
0
9
0
7
0.00
-0.00
0.0
5.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
6
59
1.02
-0.00
1.2
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
7.1
—
1.21
—
0
9
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H7_BINOCUMOVNAS and mortality.

Females

Parameter HR [95% CI] p-value
H7_BINOCUMOVNAS 1.577 [1.15, 2.17] 0.005
Birth year 0.991 [0.98, 1.0] 0.051

During the follow-up period (1.1.1998 — 31.12.2019), 66 out of 658 females with H7_BINOCUMOVNAS died.

Males

Parameter HR [95% CI] p-value
H7_BINOCUMOVNAS 2.058 [1.46, 2.9] < 0.001
Birth year 0.989 [0.98, 1.0] 0.023

During the follow-up period (1.1.1998 — 31.12.2019), 70 out of 582 males with H7_BINOCUMOVNAS died.

Mortality risk

Mortality risk for people of age

years, who have H7_BINOCUMOVNAS.

N-year risk Females Males
1 0.113% 0.431%
5 0.795% 2.599%
10 1.949% 6.692%
15 3.791% 11.912%
20 6.634% 18.919%

Relationships between endpoints

↥

Index endpoint: H7_BINOCUMOVNAS – Other and unspecified disorders of binocular movement

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data