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Other disorders of binocular movement

DOID EFO Endpoint Browser PheWeb

H7_BINOCUMOVOTH

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H51
  • Cause of death: ICD-10 — H51

2 out of 7 registries used, show all original rules.

870

4. Check minimum number of events

None

870

5. Include endpoints

901

6. Filter based on genotype QC (FinnGen only)

871

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H49-H52
Name in latin
Aliae perturbationes motus binocularis

Similar endpoints

↥

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6549 3902 2630
Only index persons 5992 3644 2348
Unadjusted period prevalence (%)
Whole population 0.10 0.11 0.07
Only index persons 0.12 0.13 0.09
Median age at first event (years)
Whole population 26.83 27.34 25.99
Only index persons 28.28 28.58 27.82

-FinnGen-

Key figures

All Female Male
Number of individuals 871 616 255
Unadjusted period prevalence (%) 0.19 0.22 0.12
Median age at first event (years) 37.21 33.56 46.02

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
901
Matched controls
9010
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H51.1
ICD-10 Finland
Convergence insufficiency and excess
+∞
307.7
540
*
H53.3
ICD-10 Finland
Other disorders of binocular vision
107.4
234.8
121
13
H53.2
ICD-10 Finland
Diplopia
24.3
185.7
137
66
H51.2
ICD-10 Finland
Internuclear ophthalmoplegia
+∞
143.7
134
*
H51.8
ICD-10 Finland
Other specified disorders of binocular movement
+∞
109.7
103
*
H50.52
ICD-10 Finland
Exophoria
160.4
96.2
100
7
H51.9
ICD-10 Finland
Disorder of binocular movement, unspecified
+∞
83.7
79
*
H50.31
ICD-10 Finland
Intermittent exotropia
+∞
71.8
68
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.0
65.3
159
370
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.9
64.1
160
380
G35
ICD-10 Finland
Multiple sclerosis
10.5
54.8
62
63
H50.1
ICD-10 Finland
Divergent concomitant strabismus
+∞
54.7
52
*
AA1AD
NOMESCO Finland
CT of head and brain
3.1
49.1
276
1126
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
13.2
44.6
43
34
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.9
44.3
145
418
TAB00
NOMESCO Finland
Lumbar puncture
5.2
44.3
97
204
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.0
40.5
219
864
109
Kela drug reimbursment
Multiple sclerosis
10.5
40.1
45
45
R51.80
ICD-10 Finland
Headache
2.9
39.7
245
1038
H53.1
ICD-10 Finland
Subjective visual disturbances
4.4
38.3
103
256
XA800
NOMESCO Finland
Neuropsychological investigation
5.0
37.4
85
184
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.9
37.3
122
350
XCK00
NOMESCO Finland
Perimetry
5.1
36.9
81
170
H50.2
ICD-10 Finland
Vertical strabismus
371.6
36.2
36
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.0
34.2
183
712
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
6.0
33.7
61
107
H51.0
ICD-10 Finland
Palsy of conjugate gaze
+∞
33.5
32
*
H52.1
ICD-10 Finland
Myopia
8.9
33.4
42
49
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
32.5
31
*
WX704
NOMESCO Finland
Intubation
3.6
31.4
111
335
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
9.4
30.5
37
41
CEC00
NOMESCO Finland
Recession of extraocular muscle
+∞
30.4
29
*
WX725
NOMESCO Finland
Noninvasive ventilation
4.2
29.3
82
209
H50.0
ICD-10 Finland
Convergent concomitant strabismus
+∞
29.3
28
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.8
29.1
94
266
M03BX01
ATC
baclofen; systemic
7.0
29.1
45
67
H52.0
ICD-10 Finland
Hypermetropia
9.8
29.0
34
36
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.8
28.4
66
145
3788X
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Other disorders of binocular eye movements
+∞
26.2
25
*
N03AX12
ATC
[U] gabapentin; oral
2.6
25.9
174
755
H50.30
ICD-10 Finland
Intermittent esotropy
+∞
25.1
24
*
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
24.4
23.6
33
14
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
23.4
229
1173
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
23.1
213
1063
H52.5
ICD-10 Finland
Disorders of accommodation
235.7
22.7
23
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
3.3
21.2
86
282
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
+∞
20.9
20
*
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.3
20.8
201
1019
WX720
NOMESCO Finland
Own respiration
3.8
20.5
65
181
N03AG01
ATC
valproic acid; systemic, rectal
3.2
20.5
87
293
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.1
20.5
91
315
R42
ICD-10 Finland
Dizziness and giddiness
2.2
20.1
202
1039
L03AX13
ATC
glatiramer acetate; parenteral
21.4
20.0
29
14
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
+∞
19.9
19
*
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
6.6
19.8
32
50
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
4.9
19.6
44
94
UKC02
NOMESCO Finland
Cystoscopy
2.6
19.1
123
519
XKC03
NOMESCO Finland
Water cystometry
5.0
18.9
41
85
N28
ICPC
Limited function/disability (N)
8.0
18.4
25
32
SPAT1301
SPAT
No procedures
1.9
18.2
299
1835
R20.2
ICD-10 Finland
Paraesthesia of skin
2.9
17.9
88
322
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.4
17.8
67
209
H50.8
ICD-10 Finland
Other specified strabismus
+∞
17.8
17
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
6.9
17.5
27
40
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.5
17.2
113
480
SPAT1263
SPAT
Sampling
1.8
17.0
405
2784
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.5
16.7
114
493
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
16.7
16
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
16.5
352
2332
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.6
16.5
107
452
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
5.6
16.3
31
57
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.3
15.5
61
196
WX702
NOMESCO Finland
Supraglottic ventilation device
3.1
15.4
68
234
XLD10
NOMESCO Finland
Gynaecological examination
7.1
15.3
23
33
N86
ICPC
Multiple sclerosis
16.4
15.3
24
15
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
2.8
15.2
81
309
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
5.4
15.2
30
57
G51.0
ICD-10 Finland
Bell palsy
4.8
15.0
34
73
A28
ICPC
Limited function/disability NOS
2.4
15.0
117
537
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
14.6
14
*
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.5
14.6
36
83
H50.51
ICD-10 Finland
Esophoria
152.4
14.5
15
*
N03AE01
ATC
clonazepam; systemic
3.2
14.5
60
199
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
14.3
115
535
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
6.3
14.3
24
39
A04
ICPC
Weakness/tiredness general
2.1
14.1
153
802
H53.4
ICD-10 Finland
Visual field defects
6.0
14.0
25
43
L28
ICPC
Limited function/disability (L)
2.2
13.9
134
671
A02BC03
ATC
lansoprazole; oral
1.9
13.6
228
1387
XKD06
NOMESCO Finland
Physiologic investigation of micturition
4.6
13.6
32
71
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
+∞
13.6
13
*
N02BF01
ATC
gabapentin; oral
2.6
13.2
78
314
N06AX11
ATC
mirtazapine; oral
1.7
13.1
301
2009
N01
ICPC
Headache
2.0
12.9
158
864
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
4.6
12.9
31
70
SPAT1260
SPAT
Consultation of another employee
2.0
12.9
164
910
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
12.9
409
2979
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
12.6
324
2227
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.3
12.5
102
476
N03AX16
ATC
[U] pregabalin
1.9
12.3
190
1123
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.3
12.3
95
434
K07.60
ICD-10 Finland
Snapping jaw
2.6
12.2
74
302
L03AB07
ATC
interferon beta-1a; parenteral
10.2
12.0
23
23
N29
ICPC
Neurological sympt/complt other
5.1
12.0
25
50
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.0
11.9
134
710
N06AX21
ATC
duloxetine; oral
2.1
11.8
120
612
N03AX14
ATC
levetiracetam; systemic
4.0
11.8
33
84
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.9
11.7
56
202
H50.9
ICD-10 Finland
Strabismus, unspecified
65.8
11.6
13
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.3
11.5
43
134
WX234
NOMESCO Finland
Paracervical blockade
2.9
11.4
55
199
SPAT1324
SPAT
Screening procedure
1.8
11.4
192
1165
OAB47, ,
SPAT
2.8
11.3
59
223
N06AA09
ATC
amitriptyline; systemic
2.4
11.3
79
345
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.4
11.2
81
359
G43.9
ICD-10 Finland
Migraine, unspecified
2.3
11.2
87
398
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
8.7
11.1
23
27
XKD00
NOMESCO Finland
Uroflowmetry
2.3
11.1
92
433
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
4.7
11.0
25
54
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
10.7
149
848
R96
ICPC
Asthma
2.2
10.7
91
433
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
10.6
214
1366
XKD03
NOMESCO Finland
Urethral pressure profilometry
4.7
10.5
24
52
N07AA02
ATC
pyridostigmine; systemic
14.4
10.5
17
12
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
10.5
349
2537
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
10.4
10
*
S06.0
ICD-10 Finland
Concussion
2.0
10.4
113
590
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.4
10.4
71
307
N03AF01
ATC
carbamazepine; oral, rectal
3.0
10.3
47
165
WX402
NOMESCO Finland
General anaesthesia
1.8
10.2
192
1201
H46
ICD-10 Finland
Optic neuritis
8.0
10.1
22
28
M50.3
ICD-10 Finland
Other cervical disc degeneration
4.5
10.1
24
54
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.2
10.0
85
403
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
10.0
73
325
N03AF02
ATC
oxcarbazepine; oral
3.1
10.0
42
141
M35.7
ICD-10 Finland
Hypermobility syndrome
4.2
9.9
26
63
KMAK, ,
NOMESCO Finland
1.6
9.9
488
3872
2AB04, ,
NOMESCO Finland
26.3
9.8
13
5
N05BA09
ATC
clobazam; oral
10.8
9.8
18
17
U07
ICPC
Urine symptom/complaint other
2.5
9.8
65
277
N02AX02
ATC
tramadol; systemic, rectal
1.6
9.7
322
2329
SPAT1231
SPAT
Assessment of adjustments needed in living environment
5.4
9.7
19
36
Z2445
NOMESCO Finland
Psychologist
2.6
9.6
57
230
F83
ICD-10 Finland
Mixed specific developmental disorders
8.5
9.6
20
24
G20
ICD-10 Finland
Parkinson disease
4.9
9.6
21
44
G04BD09
ATC
trospium; oral
4.7
9.6
22
48
R06.0
ICD-10 Finland
Dyspnoea
1.7
9.5
206
1335
R02
ICPC
Shortness of breath/dyspnoea
2.0
9.5
110
587
N03AX11
ATC
topiramate; oral
3.3
9.5
36
113
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
7.7
9.4
21
28
N05BA01
ATC
diazepam; systemic, rectal
2.0
9.4
110
590
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
9.4
434
3377
3503
FHL
Single muscle retroposition
+∞
9.4
9
*
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
9.4
9
*
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
4.4
9.4
23
53
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.6
9.3
30
85
N03AX09
ATC
lamotrigine; oral
2.4
9.3
65
284
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
9.2
225
1504
R03BA05
ATC
fluticasone; inhalant
1.7
9.2
175
1093
WX400
NOMESCO Finland
Inhalation anesthesy
2.7
9.2
51
199
SPAT1229
SPAT
Assessment of need for aid
2.6
9.1
51
200
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
11.6
9.1
16
14
G44.2
ICD-10 Finland
Tension-type headache
1.8
9.0
142
839
L12
ICPC
Hand/finger symptom/complaint
1.8
8.9
151
912
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.3
8.9
70
322
N04BB01
ATC
amantadine; oral
5.0
8.9
19
39
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
8.8
161
996
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
8.8
166
1036
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.3
8.7
69
318
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
8.7
200
1314
H02AB06
ATC
prednisolone; systemic
1.5
8.7
371
2821
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
4.0
8.6
24
61
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.6
8.6
48
188
R03CC03
ATC
terbutaline; systemic
2.9
8.6
39
137
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
4.2
8.5
22
53
G23.1
ICD-10 Finland
Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
90.9
8.4
9
*
A78
ICPC
Infectious disease other/NOS
3.2
8.4
32
101
A45
ICPC
General and Unspecified, Observ/health educat/advice/diet
3.5
8.4
28
81
K90
ICPC
Stroke/cerebrovascular accident
4.7
8.4
19
41
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
4.0
8.4
23
58
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
+∞
8.3
8
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
8.3
207
1388
A01
ICPC
Pain general/multiple sites
2.1
8.3
80
400
XMA22
NOMESCO Finland
General examination of pregnant woman
2.1
8.2
77
380
164
Kela drug reimbursment
Fingolimod
14.6
8.2
13
9
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
8.2
117
670
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
8.2
186
1218
SPAT1097
SPAT
Recording of ECG
1.9
8.2
101
552
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.5
8.2
53
224
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
8.1
99
538
B01AC07
ATC
dipyridamole; systemic
3.8
8.1
24
64
JAETT, ,
NOMESCO Finland
11.8
8.1
14
12
108
Kela drug reimbursment
Myasthenia gravis
33.7
8.1
10
*
G70.0
ICD-10 Finland
Myasthenia gravis
17.4
8.1
12
7
R53
ICD-10 Finland
Malaise and fatigue
1.6
8.1
215
1464
C07AA05
ATC
propranolol; systemic
1.6
8.1
192
1271
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
8.1
85
439
F43.1
ICD-10 Finland
Post-traumatic stress disorder
2.6
8.0
45
177
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
8.0
69
330
M79.7
ICD-10 Finland
Fibromyalgia
2.9
8.0
38
137
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.0
8.0
84
434
R52.2
ICD-10 Finland
Other chronic pain
2.8
8.0
39
143
N06AB04
ATC
citalopram; systemic
1.7
7.9
169
1087
R03AC02
ATC
salbutamol; inhalant
1.5
7.9
491
4015
Z3231
NOMESCO Finland
Registered nurse
1.6
7.8
227
1577
H53.0
ICD-10 Finland
Amblyopia ex anopsia
9.5
7.8
15
16
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.4
7.7
51
217
H54.7
ICD-10 Finland
Unspecified visual loss
15.2
7.7
12
8
P85
ICPC
Mental retardation
15.2
7.7
12
8
G46.3*I67.9
ICD-10 Finland
Brain stem stroke syndrome (I60-I67+)
45.4
7.7
9
*
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.3
7.7
29
91
A06AD11
ATC
lactulose; oral
1.9
7.7
94
512
N02CC05
ATC
almotriptan; oral
2.5
7.6
49
206
G81.9
ICD-10 Finland
Hemiplegia, unspecified
6.8
7.6
18
27
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
12.0
7.6
13
11
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
25.2
7.6
10
*
MBA20
NOMESCO Finland
Expression of placenta
6.2
7.6
19
31
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
6.2
7.6
19
31
-45
ICPC
Observ/health educat/advice/diet
3.1
7.5
31
103
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.7
7.5
23
63
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
7.5
68
332
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
7.4
279
2049
R1250
NOMESCO Finland
Evaluation of functional capability
3.5
7.4
25
73
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
80.7
7.4
8
*
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
7.4
152
967
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.6
7.4
41
161
H57.1
ICD-10 Finland
Ocular pain
2.5
7.4
44
179
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.0
7.3
76
390
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
3.0
7.3
32
110
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
7.3
264
1922
N05CD07
ATC
temazepam; oral
2.1
7.3
71
356
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.4
7.3
47
198
H47.7
ICD-10 Finland
Disorder of visual pathways, unspecified
+∞
7.3
7
*
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.2
7.3
19
46
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.9
7.3
33
116
L04AA27
ATC
[U] fingolimod
15.9
7.2
11
7
-1, ,
NOMESCO Finland
1.5
7.2
333
2549
N99
ICPC
Neurological disease other
7.4
7.2
16
22
4AA23, ,
NOMESCO Finland
30.3
7.2
9
*
CE2W4
NOMESCO Finland
Eye movement mapping
30.3
7.2
9
*
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
20.2
7.1
10
5
G04BD12
ATC
mirabegron; oral
2.0
7.1
74
381
G44.8
ICD-10 Finland
Other specified headache syndromes
3.7
7.1
22
61
A02BC02
ATC
pantoprazole; systemic
1.5
7.1
515
4303
TKC22
NOMESCO Finland
Catheterisation instruction
4.3
7.0
18
43
M01AB16
ATC
aceclofenac; oral
3.3
7.0
26
81
C07AB07
ATC
bisoprolol; oral
1.5
7.0
295
2216
C03CA01
ATC
furosemide; systemic
1.7
7.0
154
998
A03FA02
ATC
cisapride; oral, rectal
2.3
7.0
53
241
H52.2
ICD-10 Finland
Astigmatism
5.9
6.9
18
31
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
6.9
84
456
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.7
6.9
35
131
A02BA02
ATC
ranitidine; systemic
1.7
6.9
130
808
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
6.9
236
1697
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
6.9
108
637
XQ855, ,
SPAT
6.8
6.8
16
24
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
9.4
6.8
13
14
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.1
6.8
27
88
183
Kela drug reimbursment
Lamotrigin and topiramate
5.7
6.8
18
32
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
6.8
154
1005
A02BC01
ATC
omeprazole; systemic
1.6
6.8
205
1433
RS142, ,
NOMESCO Finland
16.8
6.8
10
6
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
16.8
6.8
10
6
H02.2
ICD-10 Finland
Lagophthalmos
16.8
6.8
10
6
SPAT1050
SPAT
Extensive neurological examination
3.4
6.7
24
73
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
6.7
100
580
N89
ICPC
Migraine
2.3
6.7
51
232
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
6.7
111
665
L03AB08
ATC
interferon beta-1b; parenteral
22.7
6.7
9
*
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
6.7
156
1025
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
6.7
474
3923
N06AB10
ATC
escitalopram; oral
1.6
6.7
205
1438
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.2
6.6
56
266
R25.2
ICD-10 Finland
Cramp and spasm
3.3
6.6
24
74
G43.3
ICD-10 Finland
Complicated migraine
3.3
6.6
24
74
B80
ICPC
Iron deficiency anaemia
3.0
6.6
28
95
J01DA09
ATC
[U] cefadroxil
1.5
6.6
219
1562
M03AX01
ATC
botulinum toxin; parenteral
3.7
6.5
20
55
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
6.5
85
474
HAMTE, ,
NOMESCO Finland
5.8
6.5
17
30
N05CF01
ATC
zopiclone; oral
1.5
6.5
224
1611
181
Kela drug reimbursment
Retigabine and vigabatrin
70.3
6.4
7
*
SPAT1101
SPAT
Orthostatic test
2.9
6.4
29
102
N05AH04
ATC
quetiapine; oral
1.6
6.4
166
1118
OAB50, ,
SPAT
2.4
6.4
43
185
G36.9
ICD-10 Finland
Acute disseminated demyelination, unspecified
14.4
6.4
10
7
353
Kela drug reimbursment
Cladribine and fingolimod
14.4
6.4
10
7
R33
ICD-10 Finland
Retention of urine
2.3
6.4
47
211
L04AX01
ATC
azathioprine; systemic
2.5
6.3
38
155
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
8.2
6.3
13
16
A02BC05
ATC
esomeprazole; systemic
1.5
6.3
306
2351
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.1
6.3
61
305
SPAT1234
SPAT
Support of social functional capacity
2.5
6.3
37
149
-, ,
ICD-10 Finland
3.6
6.3
20
56
R4110
NOMESCO Finland
Physiotherapy
1.5
6.3
205
1453
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
9.3
6.3
12
13
0148, ,
NOMESCO Finland
+∞
6.3
6
*
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
6.3
6
*
3789X
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Unspecified disorder of eye movements
+∞
6.3
6
*
3507
FHL
Retroposition and resection
+∞
6.3
6
*
N03AX22
ATC
perampanel; oral
26.9
6.2
8
*
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
7.1
6.2
14
20
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
3.1
6.2
25
82
SPAT1310
SPAT
Counselling related to known health issue
1.5
6.2
270
2032
J45.8
ICD-10 Finland
Mixed asthma
2.8
6.2
29
104
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.4
6.2
21
62
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.7
6.1
113
697
J01EA01
ATC
trimethoprim; systemic
1.5
6.1
210
1506
M54.1
ICD-10 Finland
Radiculopathy
2.6
6.1
34
134
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
2.6
6.1
35
140
F45.8
ICD-10 Finland
Other somatoform disorders
1.9
6.1
81
454
R13
ICD-10 Finland
Dysphagia
2.1
6.1
54
262
SAA04
NOMESCO Finland
Special examination of mouth
2.1
6.0
57
283
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.1
6.0
58
290
CS494
NOMESCO Finland
Other visual field testing
3.5
6.0
20
58
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
3.5
6.0
20
58
PA7BD
NOMESCO Finland
CT angiography of neck and brain
5.6
6.0
16
29

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
81
164
5.33
38.50
1.2
1.5
3.47
3.67
mmol/l
1.09
75
153
82
168
5.27
38.46
1.5
1.5
1966.03
777.98
e6/l
0.26
68
130
82
168
5.27
38.46
1.5
1.5
174.77
15.58
e6/l
0.51
65
125
334
1738
2.46
34.97
2.4
2.0
216.87
187.40
u/l
0.28
318
1638
74
151
5.25
34.82
1.5
1.5
—
—
—
0
0
38
43
9.18
30.87
1.2
1.0
0.41
0.10
nmol/l
—
13
7
47
71
6.93
30.00
1.2
1.2
36.17
40.66
mg/l
0.23
38
57
45
66
7.12
29.50
1.1
1.1
218.73
240.48
mg/l
0.27
40
56
42
58
7.55
29.03
1.8
1.5
—
—
—
0
0
74
177
4.47
28.74
4.8
7.9
1.12
1.24
mmol/l
0.69
68
148
48
85
5.91
26.24
1.7
1.8
—
—
—
0
0
199
927
2.47
25.46
2.2
2.3
28.51
29.72
s
2.77
187
896
546
3888
2.03
22.85
6.4
4.6
6.30
6.46
mmol/l
1.11
480
3515
404
2592
2.01
22.72
5.2
4.5
36.64
36.53
g/l
0.15
381
2426
40
69
6.02
22.44
1.7
1.5
—
—
—
0
0
130
553
2.58
19.85
2.5
2.7
10.25
10.20
g/l
0.05
117
511
443
3059
1.88
18.94
8.6
6.4
1.21
1.21
mmol/l
0.13
388
2619
326
2066
1.91
17.95
3.0
2.4
59.66
58.79
u/l
0.04
304
1921
81
283
3.05
17.89
8.0
11.9
—
—
—
0
0
98
389
2.70
17.11
3.0
3.0
145.43
160.11
ng/l
0.14
92
343
401
2752
1.82
16.88
7.7
5.9
1.21
1.22
mmol/l
1.05
379
2536
206
1139
2.05
16.69
3.9
3.3
80.97
429.74
ng/l
2.57
124
743
515
3822
1.81
16.60
7.2
5.9
0.20
0.18
e9/l
0.92
474
3387
643
5114
1.90
16.49
5.4
3.9
—
—
—
0
0
500
3685
1.80
16.43
7.0
5.6
0.55
0.55
e9/l
0.00
456
3214
500
3691
1.80
16.28
7.0
5.6
0.04
0.04
e9/l
0.02
456
3219
512
3828
1.78
15.75
6.9
5.6
2.01
1.99
e9/l
0.09
473
3434
475
3475
1.78
15.75
7.3
6.0
—
—
—
0
0
313
2032
1.83
15.49
3.8
2.5
—
—
—
0
0
177
965
2.04
14.74
1.7
1.7
1100.44
1177.66
nmol/l
0.56
141
742
375
2598
1.76
14.72
12.4
10.2
1.13
1.16
inr
0.24
81
837
611
4865
1.80
14.62
5.9
3.9
44.67
1092.34
e6/l
—
6
58
125
598
2.27
14.54
7.5
8.7
1.06
1.08
mmol/l
0.02
92
473
123
595
2.24
13.91
7.6
8.7
13.19
12.87
kpa
0.25
115
567
123
595
2.24
13.91
7.6
8.7
4.91
5.12
kpa
1.81
114
565
542
4217
1.72
13.57
9.7
8.4
4.05
4.01
e9/l
0.13
497
3685
105
488
2.30
13.04
8.1
8.9
121.98
122.02
g/l
0.01
100
475
142
745
2.08
13.03
5.1
6.1
1.05
1.08
mmol/l
0.53
135
691
346
2405
1.71
13.01
3.7
3.1
26.68
29.72
u/l
1.53
327
2285
78
318
2.59
12.88
7.3
8.5
23.89
24.42
mmol/l
0.66
72
297
77
320
2.54
12.22
5.6
6.2
—
—
—
0
0
248
1601
1.76
11.97
4.2
3.3
1.02
1.02
kg/l
0.40
43
228
445
3357
1.64
11.92
7.3
5.7
0.62
0.66
%
1.27
424
3144
461
3513
1.64
11.82
7.5
5.8
8.24
8.16
%
0.25
443
3313
271
1800
1.72
11.80
3.6
3.4
7.40
7.40
ph
0.16
42
335
130
686
2.05
11.69
1.3
1.2
—
—
—
0
0
458
3492
1.63
11.66
7.2
5.6
2.80
2.78
%
0.07
439
3284
444
3360
1.63
11.65
5.4
5.7
10.00
10.87
umol/l
1.17
421
3169
633
5259
1.68
11.26
4.2
3.7
10.19
10.31
mm/h
0.08
609
4883
811
7265
2.16
11.18
18.5
12.2
139.79
139.56
mmol/l
2.05
800
7058
105
522
2.14
11.03
8.2
9.5
96.57
95.96
%
0.47
100
503
811
7290
2.13
10.67
18.5
12.2
3.92
3.93
mmol/l
0.42
799
7067
161
950
1.85
10.36
3.4
3.6
0.83
0.82
mmol/l
0.52
153
903
467
3648
1.58
10.25
7.3
5.6
29.58
29.55
%
0.02
450
3453
559
4556
1.60
10.20
3.5
3.2
—
—
—
0
0
620
5185
1.63
10.12
7.3
6.6
77.71
77.22
u/l
0.08
591
4875
336
2442
1.60
9.96
1.9
1.8
94.39
95.33
pmol/l
0.12
164
1305
460
3599
1.57
9.90
7.1
5.5
55.85
56.10
%
0.18
444
3402
124
700
1.89
9.11
2.3
2.0
383.90
380.78
nmol/l
0.06
112
646
208
1374
1.67
8.91
1.5
1.4
21.11
20.60
nmol/l
0.19
190
1200
225
1517
1.64
8.90
4.6
4.0
—
—
—
0
0
106
579
1.94
8.58
7.1
4.6
2.02
1.78
mmol/l
0.37
96
471
248
1736
1.59
8.34
2.4
2.1
2.38
2.83
mg/l
2.83
222
1487
95
510
1.96
8.09
2.4
2.3
6.08
21.69
au/ml
—
5
44
459
3690
1.50
8.07
4.2
3.2
0.00
0.00
estimate
-0.00
78
767
678
5934
1.58
7.83
5.0
4.0
14.57
14.48
pmol/l
0.45
643
5474
71
356
2.08
7.30
2.0
1.2
—
—
—
0
0
54
246
2.27
7.05
9.4
3.7
0.64
0.66
%
0.16
54
246
17
27
6.40
6.96
1.3
1.4
125.24
137.96
nmol/l
0.45
17
27
593
5101
1.48
6.91
3.5
2.9
35.98
38.29
u/l
0.40
564
4855
451
3696
1.44
6.71
5.8
4.4
0.00
0.00
estimate
0.50
70
734
147
952
1.65
6.66
2.3
2.2
13.06
14.04
umol/l
0.95
140
882
89
501
1.86
6.58
7.8
4.0
4.77
4.72
kpa
0.09
89
483
762
6943
1.63
6.53
5.8
4.6
1.69
1.97
mu/l
1.02
728
6503
76
408
1.94
6.48
2.5
2.5
67.14
67.05
g/l
0.04
70
374
130
824
1.68
6.39
1.8
1.5
—
—
—
0
0
377
3013
1.43
6.31
4.1
3.0
5.65
5.86
ph
0.63
30
283
842
7906
1.99
6.28
16.4
10.6
—
—
—
0
0
182
1259
1.56
6.25
1.6
1.6
436.99
23805568.81
pmol/l
1.32
158
1088
450
3730
1.41
6.06
4.2
3.2
0.00
0.01
estimate
0.80
69
708
77
427
1.88
5.97
4.2
4.0
85.92
70.23
ng/l
0.79
69
389
132
865
1.62
5.68
2.3
2.2
2.49
2.41
g/l
0.83
127
792
77
442
1.81
5.37
2.2
2.7
72.96
70.35
e9/l
0.23
61
326
100
623
1.68
5.25
3.0
2.7
1.79
1.72
%
0.26
93
559
21
70
3.05
5.13
1.4
1.2
—
—
nmol/l
—
0
0
180
1293
1.49
5.12
1.3
1.3
17.58
31.72
iu/ml
2.16
52
393
262
2022
1.42
5.10
1.4
1.3
0.55
1.96
u/ml
3.98
63
543
419
3497
1.37
5.10
3.1
2.5
—
—
—
0
0
76
442
1.79
5.09
1.4
1.4
—
—
—
0
0
227
1711
1.44
5.03
1.7
1.6
1.42
1.35
mmol/l
0.36
214
1470
441
3722
1.36
4.95
3.3
2.8
91.47
86.08
ug/l
0.20
419
3490
828
7822
1.72
4.79
11.0
8.7
24.45
25.47
u/l
1.29
809
7573
75
443
1.76
4.77
2.2
1.8
1.10
1.33
g/l
1.21
68
412
100
640
1.63
4.74
3.2
2.3
5393.97
4370.45
u/l
0.15
43
277
32
139
2.35
4.73
1.2
1.2
—
—
—
0
0
170
1228
1.47
4.68
1.3
1.3
1.81
10.82
u/ml
5.64
62
507
57
312
1.88
4.64
1.9
2.2
—
—
—
0
0
82
501
1.70
4.64
12.5
8.8
—
—
—
0
0
85
525
1.68
4.62
3.0
3.4
4.59
4.64
pmol/l
0.19
76
472
118
791
1.57
4.61
2.4
2.3
22.27
23.66
%
0.45
85
684
796
7460
1.58
4.60
16.9
11.3
19.87
20.29
mg/l
0.14
634
5733
269
2120
1.38
4.56
3.2
3.1
2.33
2.35
mmol/l
2.55
249
1922
133
920
1.52
4.52
2.0
1.9
—
—
—
0
0
218
1674
1.40
4.28
4.2
3.8
95.22
93.63
%
0.48
209
1622
54
302
1.84
4.14
1.2
1.2
0.18
1.46
u/ml
—
9
21
351
2918
1.33
4.13
2.6
2.3
74.98
73.93
nmol/l
0.29
324
2681
142
1028
1.45
3.85
1.3
1.3
477.78
540.30
titre
0.15
18
199
29
133
2.22
3.83
2.3
1.8
13.72
13.04
%
1.07
29
133
14
38
3.73
3.80
2.6
3.0
208.33
267.39
e6/l
—
6
23
52
298
1.79
3.71
2.5
2.9
21.14
21.49
s
0.25
43
262
147
1084
1.43
3.61
2.2
2.4
111.26
97.01
ug/g
0.11
112
839
22
92
2.43
3.58
1.3
1.6
—
—
—
0
0
18
68
2.68
3.58
1.5
1.3
6.26
5.81
g/l
0.29
12
49
18
68
2.68
3.58
1.5
1.3
0.31
0.36
g/l
0.39
12
47
18
68
2.68
3.58
1.5
1.3
2.87
2.64
g/l
0.30
12
48
211
1658
1.36
3.54
4.4
3.2
—
—
—
0
0
83
548
1.57
3.49
1.5
1.3
152.55
226.94
u/ml
0.62
71
508
21
87
2.45
3.49
1.3
1.5
—
—
—
0
0
14
48
2.95
3.31
1.1
1.1
—
—
—
0
0
12
33
3.67
3.30
2.1
4.7
91.60
133.21
umol/l
—
5
19
41
227
1.84
3.29
2.0
2.0
2.17
4.83
iu/l
2.71
18
80
9
20
4.53
3.12
11.1
9.7
—
—
—
0
0
11
30
3.70
3.09
1.0
2.7
328.91
589.20
u/ml
1.38
11
30
871
8460
1.89
3.03
24.5
16.7
263.08
258.99
e9/l
1.06
866
8260
31
162
1.95
2.98
1.2
1.4
—
—
—
0
0
205
1643
1.32
2.98
2.2
1.9
0.73
1.07
mg/l
2.50
160
1234
17
69
2.49
2.97
1.5
1.3
—
—
—
0
0
142
1077
1.38
2.96
3.2
2.5
0.81
0.90
e6/l
0.20
73
572
18
76
2.40
2.90
1.5
1.1
—
—
—
0
0
11
32
3.47
2.90
3.2
3.6
—
—
—
0
0
871
8468
1.86
2.89
24.5
16.7
4.49
4.52
e12/l
1.20
864
8260
871
8469
1.85
2.88
24.5
16.7
6.85
6.73
e9/l
0.60
864
8257
80
549
1.50
2.86
2.0
2.7
0.22
0.22
g/l
0.06
73
520
12
38
3.19
2.86
1.3
1.1
1817.25
1598.61
miu/ml
0.19
12
38
870
8460
1.82
2.82
24.9
16.7
40.14
40.17
%
0.06
755
8018
36
202
1.81
2.81
1.4
2.3
1.41
1.32
g/l
0.20
27
177
35
195
1.83
2.79
6.4
4.8
—
—
—
0
0
6
10
6.03
2.70
1.8
1.2
—
—
—
0
0
224
1849
1.28
2.58
3.9
2.8
0.20
0.34
e6/l
1.80
166
1353
55
356
1.58
2.57
9.8
5.1
24.47
23.92
mmol/l
0.96
55
351
5
7
7.18
2.55
1.2
1.7
—
—
—
0
0
243
2870
0.79
2.53
1.7
1.9
—
—
—
0
0
25
129
1.96
2.52
1.9
1.7
186.48
192.09
pmol/l
0.09
25
119
221
1829
1.28
2.49
3.8
2.8
—
—
—
0
0
252
2133
1.25
2.34
3.5
2.8
—
—
—
0
0
258
2196
1.25
2.27
4.0
3.1
16.80
53.96
ng/l
1.22
152
1243
6
13
4.64
2.27
1.0
1.2
—
—
—
0
0
656
6148
1.25
2.27
5.2
4.7
37.63
38.39
mmol/mol
1.48
627
5791
10
35
2.88
2.21
2.2
2.8
77.60
109.91
nmol/l
—
10
35
8
24
3.35
2.18
2.1
2.0
22.63
15.73
umol/l
—
8
24
22
115
1.94
2.17
1.5
1.8
0.61
0.77
g/l
0.34
16
89
210
1757
1.25
2.14
1.6
1.4
2.16
2.14
g/l
0.05
129
1091
226
1910
1.24
2.11
2.7
3.2
7.39
7.98
mmol/l
1.05
199
1657
66
466
1.45
2.10
1.3
1.2
—
—
—
0
0
8
26
3.10
2.01
1.5
1.2
2.37
0.94
u/ml
—
8
26
19
97
1.98
2.01
3.7
4.0
—
—
—
0
0
237
2025
1.23
1.99
4.1
2.9
32.43
106.19
e6/l
1.30
176
1514
186
1548
1.25
1.98
2.7
3.3
2056.48
296.61
mg/l
1.31
112
1028
5
11
4.56
1.94
1.2
1.5
-2.12
2.83
mmol/l
—
5
11
711
6764
1.24
1.92
4.3
3.7
5.64
5.73
mmol/l
1.35
663
6273
25
418
0.59
1.90
1.7
1.4
—
—
—
0
0
143
1160
1.28
1.89
1.6
1.6
—
—
—
0
0
33
205
1.63
1.88
3.1
1.9
0.74
3.26
ug/l
1.10
27
186
25
416
0.59
1.87
1.7
1.4
—
—
—
0
0
8
28
2.87
1.86
2.9
2.0
—
—
—
0
0
48
327
1.49
1.85
1.4
1.4
16.79
9.47
u/l
0.42
43
269
14
66
2.14
1.82
3.4
2.7
—
—
—
0
0
99
769
1.32
1.81
2.6
2.9
9.99
7.14
umol/l
0.39
80
646
14
67
2.11
1.76
3.4
2.6
106.93
105.21
mmol/l
0.83
14
67
14
67
2.11
1.76
3.4
2.6
3.98
3.99
mmol/l
0.05
14
67
243
2780
0.83
1.76
2.6
2.4
—
—
—
0
0
82
623
1.35
1.75
2.1
2.3
38.04
112.68
u/l
0.46
70
515
7
24
2.93
1.72
1.3
1.2
195.43
100.41
nmol/l
—
7
15
5
13
3.86
1.71
1.2
1.0
—
—
—
0
0
21
118
1.80
1.71
18.7
5.6
—
—
—
0
0
27
427
0.62
1.67
1.7
1.5
—
—
—
0
0
45
312
1.47
1.62
7.3
5.2
—
—
—
0
0
30
190
1.60
1.62
1.2
1.3
—
—
—
0
0
5
14
3.59
1.61
1.0
1.0
—
—
—
0
0
5
14
3.59
1.61
1.0
1.0
—
—
—
0
0
5
14
3.59
1.61
1.0
1.0
—
—
—
0
0
77
995
0.75
1.61
1.4
1.3
—
—
—
0
0
24
144
1.68
1.59
2.3
1.5
—
—
—
0
0
32
207
1.57
1.58
1.9
1.6
37.03
39.77
nmol/l
0.27
32
201
20
114
1.77
1.57
1.6
1.7
—
1666.67
—
0
6
111
895
1.27
1.56
1.2
1.2
—
—
—
0
0
12
57
2.12
1.55
1.1
1.2
—
—
—
0
0
68
514
1.35
1.52
2.1
2.6
4.31
5.93
e9/l
1.09
59
452
126
1035
1.25
1.52
3.4
2.7
3.62
2.89
e6/l
0.24
58
537
65
488
1.36
1.52
5.5
3.0
—
—
—
0
0
190
1631
1.21
1.51
3.2
3.9
8.87
9.32
mg/mmol
0.05
110
1055
87
685
1.30
1.48
1.2
1.2
129.05
159.13
iu/ml
0.29
38
285
280
2496
1.18
1.46
4.8
3.4
49.11
81.28
e6/l
0.68
185
1637
163
1384
1.22
1.45
3.6
2.3
4.31
7.23
e6/l
3.54
149
1224
5
16
3.14
1.44
2.2
1.2
—
—
—
0
0
73
564
1.32
1.42
3.5
4.4
0.96
0.99
%
0.03
28
182
15
81
1.87
1.40
2.3
3.0
—
—
—
0
0
159
1352
1.21
1.40
4.0
2.6
569.05
552.21
mosm/kgh2o
0.44
137
1157
67
513
1.33
1.39
3.3
4.4
0.54
0.62
%
0.13
24
154
25
158
1.60
1.38
1.2
1.1
6.05
7.26
u/ml
0.15
14
67
22
135
1.65
1.37
1.7
1.4
6.00
7.15
mmol/l
2.15
22
122
28
183
1.55
1.36
1.5
1.4
245.06
324.02
ug/g
1.55
16
103
89
713
1.28
1.34
1.3
1.3
—
—
—
0
0
67
517
1.32
1.33
3.6
4.5
3.45
0.16
%
0.46
20
133
12
61
1.98
1.33
2.8
5.6
6.66
6.56
mmol/l
—
7
49
26
168
1.56
1.32
2.5
2.6
—
—
—
0
0
6
24
2.51
1.30
1.0
1.5
—
—
—
0
0
16
91
1.77
1.29
1.1
1.3
—
62.80
—
0
6
46
337
1.38
1.28
1.1
1.1
—
—
—
0
0
15
84
1.80
1.27
2.5
2.3
—
—
—
0
0
32
219
1.48
1.27
7.6
5.3
9.57
8.78
kpa
2.51
32
213
71
558
1.30
1.25
1.5
1.4
35.74
23.28
iu/l
1.00
61
469
17
100
1.71
1.24
1.0
1.5
—
—
—
0
0
40
288
1.41
1.23
8.4
5.5
24.76
24.71
mmol/l
0.06
40
277
41
297
1.40
1.22
1.7
1.6
—
—
—
0
0
5
19
2.64
1.21
4.8
2.1
—
—
—
0
0
23
148
1.57
1.21
1.1
1.2
5.10
5.92
u/ml
—
10
62
8
38
2.11
1.18
1.1
2.3
30.63
29.13
umol/l
—
8
38
21
133
1.59
1.18
2.8
3.6
57.19
56.71
%
0.05
21
133
10
50
2.01
1.16
1.5
1.1
—
—
—
0
0
46
605
0.75
1.13
1.4
1.4
—
—
—
0
0
148
1277
1.19
1.13
4.7
4.6
16.88
2.32
ug/l
0.73
137
1148
10
51
1.97
1.11
2.8
1.2
8.02
5.69
ug/l
—
10
42
48
366
1.33
1.07
1.1
1.1
—
—
—
0
0
20
129
1.56
1.06
2.8
3.3
3.83
4.27
e9/l
0.30
20
129
156
1361
1.18
1.06
3.0
3.1
1424.25
1034.25
ng/l
0.44
125
1132
7
34
2.07
1.03
1.4
1.2
—
—
—
0
0
69
847
0.80
1.02
1.2
1.2
—
—
—
0
0
9
48
1.88
1.00
1.1
8.8
10.73
11.94
%
—
9
48
96
806
1.21
1.00
1.5
1.3
—
—
—
0
0
54
425
1.29
0.98
6.9
4.8
7.42
7.41
ph
—
9
46
21
140
1.51
0.98
1.2
1.1
—
—
—
0
0
88
736
1.22
0.95
1.5
1.5
—
—
—
0
0
11
62
1.78
0.94
1.1
1.0
—
—
—
0
0
7
37
1.90
0.94
2.4
3.6
—
—
—
0
0
136
1188
1.17
0.92
1.5
1.5
—
—
—
0
0
22
314
0.69
0.92
1.5
1.7
—
—
—
0
0
215
1948
1.14
0.88
1.8
1.7
—
—
—
0
0
8
43
1.87
0.87
1.1
1.2
—
—
—
0
0
50
397
1.27
0.87
2.5
2.1
4.07
6.65
ug/l
1.69
42
352
179
1607
1.14
0.85
1.7
1.7
—
—
—
0
0
6
31
1.94
0.84
1.2
1.2
122.67
177.99
mmol/24h
—
6
31
11
178
0.61
0.83
1.7
2.2
—
—
—
0
0
117
1020
1.17
0.82
1.7
1.9
—
—
—
0
0
24
172
1.41
0.81
1.2
1.1
3.63
4.49
u/ml
0.15
15
86
19
130
1.47
0.81
2.6
2.4
190.66
114.69
ug/min
0.21
14
76
8
48
1.67
0.79
1.1
1.0
—
—
—
0
0
44
349
1.27
0.79
1.5
1.3
—
—
—
0
0
12
74
1.63
0.78
1.2
1.1
0.41
2.50
u/ml
—
5
33
13
82
1.59
0.78
1.1
1.1
0.25
1.77
u/ml
—
6
31
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
715
6970
1.13
0.73
4.1
3.7
4.66
4.69
mmol/l
0.37
684
6586
64
535
1.21
0.73
3.9
4.5
0.26
0.13
%
0.42
19
152
7
38
1.85
0.73
1.1
1.2
272.00
500.18
u/l
—
7
33
58
480
1.22
0.73
1.3
1.2
—
—
—
0
0
9
56
1.61
0.72
2.1
1.4
4.88
5.77
mmol/l
—
9
56
26
194
1.35
0.72
1.3
1.4
0.19
0.39
nmol/l
4.09
18
165
11
68
1.63
0.72
2.3
4.1
—
—
—
0
0
258
2393
1.11
0.71
2.1
2.0
—
—
—
0
0
9
59
1.53
0.68
1.0
1.1
—
—
—
0
0
211
1943
1.11
0.67
5.1
3.4
0.00
0.01
estimate
1.34
73
723
22
162
1.37
0.66
1.8
2.5
—
—
—
0
0
24
180
1.34
0.65
1.6
1.3
250.50
233.93
u/ml
0.11
12
110
18
129
1.40
0.63
2.3
2.6
1.82
2.36
mmol/l
0.90
11
83
24
181
1.33
0.63
1.5
1.5
—
—
—
0
0
8
50
1.61
0.61
2.3
3.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.7
—
—
—
0
0
23
176
1.31
0.57
1.0
1.1
—
—
—
0
0
15
107
1.41
0.55
1.8
2.4
—
—
—
0
0
23
177
1.31
0.55
1.0
1.1
—
—
—
0
0
6
38
1.58
0.54
2.8
2.6
62.00
46.24
umol/l
—
6
32
24
187
1.29
0.53
5.6
4.4
1.35
1.38
mmol/l
0.09
24
181
20
152
1.32
0.52
7.1
4.1
—
—
—
0
0
9
65
1.39
0.50
1.0
1.1
—
—
—
0
0
27
216
1.26
0.50
1.2
1.1
0.54
2.03
u/ml
1.09
16
102
10
67
1.50
0.50
1.2
1.2
—
—
—
0
0
10
143
0.70
0.48
2.4
3.1
24.40
27.35
mg/l
—
5
86
28
227
1.24
0.47
1.2
1.1
3.22
7.63
u/ml
0.97
21
129
20
156
1.29
0.45
1.8
1.7
—
—
—
0
0
244
2575
0.93
0.44
1.6
1.7
—
—
—
0
0
10
69
1.45
0.44
1.2
1.1
—
—
—
0
0
679
6661
1.08
0.43
3.6
3.3
1.28
1.23
mmol/l
1.01
639
6257
67
753
0.88
0.43
1.4
1.4
—
—
—
0
0
19
149
1.28
0.42
1.2
1.1
0.01
0.41
u/ml
—
10
51
29
240
1.22
0.42
1.2
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
706
6941
1.08
0.41
4.0
3.7
1.45
1.48
mmol/l
0.85
670
6534
45
518
0.86
0.41
1.4
1.4
—
—
—
0
0
30
250
1.21
0.40
3.7
4.0
0.15
0.29
g/l
—
9
114
18
141
1.28
0.40
1.2
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
5.7
—
1.20
—
0
19
323
3361
0.94
0.39
9.9
8.3
0.00
0.00
e9/l
0.42
268
2747
68
756
0.89
0.38
2.8
2.9
0.57
0.73
ug/l
1.63
43
475
5
76
0.66
0.36
1.2
1.1
—
—
—
0
0
17
135
1.26
0.35
2.4
2.5
—
—
—
0
0
35
302
1.17
0.34
2.3
2.2
—
—
—
0
0
49
550
0.88
0.33
1.9
1.8
—
—
—
0
0
6
87
0.69
0.33
2.8
3.6
32.63
3255.07
u/ml
—
6
81
6
89
0.67
0.33
1.3
1.8
—
—
—
0
0
28
238
1.18
0.33
1.1
1.2
—
—
—
0
0
54
486
1.12
0.30
3.6
4.2
7.71
31.40
ug/l
0.75
38
390
21
175
1.20
0.30
1.2
1.3
—
—
—
0
0
10
75
1.34
0.30
1.1
1.1
0.32
9.63
u/ml
—
5
24
171
1625
1.06
0.29
4.3
3.3
—
—
—
0
0
215
2243
0.95
0.28
2.7
2.1
—
—
—
0
0
14
173
0.81
0.28
1.4
1.2
—
—
—
0
0
25
214
1.17
0.28
1.3
1.1
3.13
1.65
u/ml
0.35
16
121
8
63
1.27
0.28
3.3
1.9
—
—
—
0
0
50
551
0.90
0.26
1.8
1.8
—
—
—
0
0
112
1054
1.07
0.26
2.6
2.5
2.42
2.43
mmol/l
0.16
102
918
20
169
1.19
0.26
1.5
1.5
118.56
111.87
u/ml
—
9
31
716
7079
1.06
0.25
4.5
4.0
2.78
2.81
mmol/l
0.32
681
6638
51
557
0.91
0.23
1.8
1.9
—
—
—
0
0
14
115
1.22
0.23
1.5
1.3
—
—
—
0
0
5
39
1.28
0.23
3.2
3.0
37000.00
39543.72
ug/l
—
5
39
11
88
1.25
0.22
1.4
4.1
—
76.77
—
0
25
10
79
1.27
0.22
2.2
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
166
1597
1.05
0.20
2.4
2.5
303.81
5495.67
umol/l
5.14
140
1425
15
128
1.17
0.18
3.0
2.6
—
—
—
0
0
63
671
0.93
0.18
4.7
3.3
—
—
—
0
0
8
70
1.14
0.16
1.0
1.8
—
—
—
0
0
52
554
0.93
0.15
1.8
1.8
—
—
—
0
0
48
512
0.93
0.15
1.9
1.9
—
—
—
0
0
13
112
1.16
0.14
2.0
2.4
—
—
—
0
0
10
118
0.85
0.14
1.3
1.4
—
—
—
0
0
41
438
0.93
0.13
1.9
1.8
—
—
—
0
0
43
457
0.94
0.12
2.5
2.3
—
—
—
0
0
10
86
1.16
0.11
1.9
1.7
—
—
—
0
0
15
135
1.11
0.09
1.2
1.1
—
—
—
0
0
5
46
1.09
0.09
1.0
1.2
—
—
—
0
0
5
47
1.06
0.09
2.0
2.9
—
—
—
0
0
5
48
1.04
0.09
1.4
1.4
28.64
33.27
g/l
—
5
42
6
54
1.11
0.09
2.7
1.9
—
—
—
0
0
39
410
0.95
0.08
1.4
1.3
224.14
251.28
miu/ml
0.20
16
211
6
58
1.03
0.08
1.0
1.2
—
—
—
0
0
5
61
0.82
0.08
1.0
1.1
—
—
—
0
0
5
60
0.83
0.08
1.2
1.3
1.32
1.41
nmol/l
—
5
52
5
62
0.81
0.08
1.8
1.7
—
—
—
0
0
8
76
1.05
0.07
1.5
1.6
—
—
—
0
0
7
81
0.86
0.07
1.1
1.1
20.44
12.68
u/l
—
7
68
33
317
1.04
0.05
4.1
2.2
0.07
0.16
e6/l
1.14
33
305
31
323
0.96
0.05
5.3
3.1
—
—
—
0
0
186
1839
1.01
0.04
7.5
6.2
—
—
—
0
0
13
140
0.93
0.04
1.0
1.1
2.02
2.05
u/ml
—
8
68
54
526
1.03
0.04
4.8
3.8
—
—
—
0
0
22
231
0.95
0.04
1.3
1.2
—
—
—
0
0
15
141
1.06
0.03
1.1
1.2
—
—
—
0
0
55
560
0.98
0.02
1.7
1.7
—
—
—
0
0
37
378
0.98
0.01
2.2
2.3
—
—
—
0
0
166
1669
0.99
0.01
2.4
2.0
—
—
—
0
0
14
134
1.05
0.00
1.1
1.0
—
—
—
0
0
46
456
1.01
0.00
1.2
1.1
—
107.58
—
0
12
23
235
0.98
0.00
6.7
8.0
—
—
—
0
0
5
49
1.02
0.00
1.0
1.0
—
—
—
0
0
5
49
1.02
0.00
1.6
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
15.22
—
0
5
5
55
0.91
-0.00
1.2
1.2
—
—
—
0
0
9
90
1.00
-0.00
1.1
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.3
—
—
—
0
0
6
63
0.95
-0.00
1.3
1.3
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
9.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
25
250
1.00
-0.00
1.3
1.2
0.30
3.93
u/ml
4.56
17
143
0
8
0.00
-0.00
0.0
5.4
—
—
—
0
0
25
250
1.00
-0.00
2.6
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
19.18
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.3
—
—
—
0
0
6
67
0.89
-0.00
1.3
1.7
31.83
32.39
pg
—
6
67
9
90
1.00
-0.00
2.9
3.3
0.78
1.15
%
—
9
82

Mortality – FinRegistry

↥

Association

Association between endpoint H7_BINOCUMOVOTH and mortality.

Females

Parameter HR [95% CI] p-value
H7_BINOCUMOVOTH 1.212 [1.03, 1.43] 0.023
Birth year 0.996 [0.99, 1.0] 0.359

During the follow-up period (1.1.1998 — 31.12.2019), 225 out of 3488 females with H7_BINOCUMOVOTH died.

Males

Parameter HR [95% CI] p-value
H7_BINOCUMOVOTH 1.596 [1.34, 1.91] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 292 out of 2306 males with H7_BINOCUMOVOTH died.

Mortality risk

Mortality risk for people of age

years, who have H7_BINOCUMOVOTH.

N-year risk Females Males
1 0.129% 0.356%
5 0.853% 1.789%
10 1.879% 4.371%
15 3.71% 8.414%
20 6.334% 13.823%

Relationships between endpoints

↥

Index endpoint: H7_BINOCUMOVOTH – Other disorders of binocular movement

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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