No definition available.
Congenital malformations of great arteries
DOID EFO Endpoint Browser PheWeb
Q17_CONGEN_MALFO_GREAT_ARTERIES
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
797 |
4. Check minimum number of eventsNone |
797 |
5. Include endpointsNone |
797 |
6. Filter based on genotype QC (FinnGen only) |
797 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_CIRCULATO_SYSTEM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q2
- Name in latin
- Malformationes congenitae arteriarum magnarum
Similar endpoints
↥List of similar endpoints to
Congenital malformations of great arteries
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of heart and great arteries
- Congenital malformations of the circulatory system
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 11820 | 5910 | 5895 |
| Only index persons | 7116 | 3524 | 3592 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.17 | 0.17 | 0.16 |
| Only index persons | 0.13 | 0.13 | 0.14 |
| Median age at first event (years) | |||
| Whole population | 0.49 | 0.43 | 0.38 |
| Only index persons | 3.34 | 3.12 | 3.56 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 797 | 411 | 386 |
| Unadjusted period prevalence (%) | 0.15 | 0.14 | 0.17 |
| Median age at first event (years) | 13.14 | 12.71 | 13.59 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 710
- Matched controls
- 6999
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q25.1
ICD-10 Finland
Coarctation of aorta
+∞
323.0
308
*
Q25.0
ICD-10 Finland
Patent ductus arteriosus
+∞
298.4
266
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
14.0
197.7
411
627
Q23.11
ICD-10 Finland
Bicuspid aortic valve
1608.9
140.9
133
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
37.3
140.7
182
64
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
11.5
132.9
280
375
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
23.3
127.8
190
108
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
29.3
125.5
173
76
XF400
NOMESCO Finland
ECG with 12 standard connections
8.1
115.8
316
633
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
+∞
98.8
93
*
74719
ICD-8 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta
+∞
91.2
86
*
Q21.10
ICD-10 Finland
Persistent ostium secundum
+∞
89.0
84
*
201
Kela drug reimbursment
Chronic cardiac insufficiency
24.6
88.7
128
62
FM2CE
NOMESCO Finland
NA
12.6
87.4
166
165
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
+∞
86.9
82
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.9
85.2
412
1528
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
23.5
82.1
120
60
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
10.3
77.6
164
198
B01AA03
ATC
warfarin; systemic
8.4
77.3
187
285
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
+∞
70.7
67
*
XF600
NOMESCO Finland
Bloodpressure measurement
7.7
70.0
180
297
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
+∞
68.5
65
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.3
66.3
159
234
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
72.7
64.3
73
11
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
58.0
62.9
74
14
31
HP
Congenital heart failure surgery
654.7
62.5
61
*
61
HP
Catheterization and pressure measurement of the left side of the heart
71.5
58.0
66
10
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.0
56.8
214
557
XF404
NOMESCO Finland
Ambulatory ECG
7.6
56.3
143
226
XF402
NOMESCO Finland
ECG with work load test
7.9
55.7
137
206
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
203.3
55.5
57
*
I35.0
ICD-10 Finland
Aortic (valve) stenosis
18.3
55.1
87
53
TPH07
NOMESCO Finland
Cathetrisation of artery
6.1
54.9
167
337
C03CA01
ATC
furosemide; systemic
5.3
52.7
182
426
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
+∞
49.3
47
*
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
43.0
48.4
60
15
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
+∞
48.2
46
*
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
27.4
47.8
66
26
FDE32
NOMESCO Finland
Percutaneous transluminal closure of patent ductus arteriosus
+∞
47.2
45
*
Q25.3
ICD-10 Finland
Stenosis of aorta
+∞
47.2
45
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.2
43.6
316
1394
62
HP
Catheterization and pressure measurement of the right side of the heart
230.8
43.2
44
*
C03DA01
ATC
spironolactone; oral
7.1
42.5
110
175
XFE00
NOMESCO Finland
Epicardial ultrasonography
18.4
41.6
65
38
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
4.9
41.0
149
360
Q25.6
ICD-10 Finland
Stenosis of pulmonary artery
+∞
40.8
39
*
Q25.40
ICD-10 Finland
Aortic hypoplasia
+∞
40.8
39
*
Q25.48
ICD-10 Finland
Other congenital malformations of the aorta
+∞
39.8
38
*
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
+∞
39.8
38
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.2
39.0
270
1129
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
+∞
38.7
37
*
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
42.2
38.7
48
12
XF622
NOMESCO Finland
Measurement of minute volume of heart
71.3
36.1
41
6
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
370.3
36.1
36
*
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
+∞
34.5
33
*
Q21.30
ICD-10 Finland
Tetralogy of Fallot
+∞
32.4
31
*
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
+∞
32.4
31
*
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
24.8
32.0
45
19
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
117.2
31.8
34
*
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
+∞
31.3
30
*
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
40.6
31.3
39
10
Z98.8
ICD-10 Finland
Other specified postsurgical states
21.0
31.0
46
23
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
113.6
30.7
33
*
C01AA05
ATC
digoxin; systemic
9.7
30.7
64
71
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
+∞
30.3
29
*
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
20.5
30.2
45
23
C07AB07
ATC
bisoprolol; oral
2.8
28.6
235
1056
PD5DG
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
277.2
26.8
27
*
WX402
NOMESCO Finland
General anaesthesia
2.8
26.2
201
858
WX872
NOMESCO Finland
Intensive care
7.4
26.1
64
93
74709
ICD-8 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
+∞
26.1
25
*
WX882
NOMESCO Finland
High dependency care
3.8
25.7
119
352
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
+∞
25.0
24
*
FBE35
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery with insertion of stent
+∞
24.0
23
*
205
Kela drug reimbursment
Chronic hypertension
3.2
23.7
139
493
Q21.0
ICD-10 Finland
Ventricular septal defect
+∞
22.9
22
*
5513
FHL
Coarctation resection, plastic or bypass
+∞
22.9
22
*
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
+∞
21.9
21
*
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
+∞
21.9
21
*
K83
ICPC
Heart valve disease NOS
39.5
21.7
27
7
R4110
NOMESCO Finland
Physiotherapy
2.4
21.3
235
1208
FDJ42
NOMESCO Finland
Percutaneous transluminal angioplasty of thoracic aorta in coarctation
+∞
20.8
20
*
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
+∞
20.8
20
*
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
+∞
20.8
20
*
FDJ00
NOMESCO Finland
End to end reconstruction of aorta for coarctation
+∞
20.8
20
*
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
+∞
20.8
20
*
Q20.1
ICD-10 Finland
Double outlet right ventricle
+∞
20.8
20
*
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
33.2
20.2
26
8
C07AB02
ATC
metoprolol; systemic
3.3
20.1
111
374
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.6
20.0
98
302
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
21.2
19.9
29
14
Q20.48
ICD-10 Finland
Single ventricle
+∞
19.8
19
*
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
+∞
19.8
19
*
XF620
NOMESCO Finland
Examination of circulation with color method
106.6
19.5
21
*
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
106.6
19.5
21
*
RS224
NOMESCO Finland
NA
10.9
18.9
36
34
WX704
NOMESCO Finland
Intubation
4.2
18.9
74
187
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
+∞
18.7
18
*
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
+∞
18.7
18
*
G04BE03
ATC
sildenafil; oral
12.6
18.6
33
27
I50.9
ICD-10 Finland
Heart failure, unspecified
4.7
18.5
64
143
C01BD01
ATC
amiodarone; systemic
10.9
17.9
34
32
XQ903
NOMESCO Finland
Production of other scan or drawing
53.2
17.9
21
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
3.4
17.8
93
301
Q26.1
ICD-10 Finland
Persistent left superior vena cava
+∞
17.7
17
*
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
+∞
17.7
17
*
Q25.9
ICD-10 Finland
Congenital malformation of great arteries, unspecified
+∞
17.7
17
*
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
6.0
17.6
49
85
PD5BD
NOMESCO Finland
Extensive CT of aorta
15.3
16.6
27
18
WX892
NOMESCO Finland
Monitored bed care
3.3
16.4
87
284
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
20.4
16.4
24
12
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
40.5
16.3
20
5
TFP20
NOMESCO Finland
Cardiodefibrillation
5.2
15.9
50
101
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
+∞
15.6
15
*
Q23.3
ICD-10 Finland
Congenital mitral insufficiency
+∞
15.6
15
*
Q25.8
ICD-10 Finland
Other congenital malformations of great arteries
+∞
15.6
15
*
Q21.19
ICD-10 Finland
Atrial septal defect NOS
+∞
15.6
15
*
FDE10
NOMESCO Finland
Ligature of patent ductus arteriosus
+∞
15.6
15
*
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
7.0
15.5
38
56
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
15.3
153
731
UGC02
NOMESCO Finland
Rigid bronchoscopy
9.9
14.7
29
30
Q21.32
ICD-10 Finland
Pulmonary atresia with Fallot ventricular septal defect
+∞
14.6
14
*
Q22.0
ICD-10 Finland
Pulmonary valve atresia
+∞
14.6
14
*
7470A
ICD-9 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
150.9
14.4
15
*
PC1BD
NOMESCO Finland
Extensive CT of thoracic aorta
150.9
14.4
15
*
PD5BG
NOMESCO Finland
MRI examination of thoracal and abdominal aortta with high intensity magnet
150.9
14.4
15
*
FC1AC
NOMESCO Finland
Angiography of thoracal aortta
36.3
14.4
18
5
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
7.4
14.0
33
46
XF640
NOMESCO Finland
NA
8.5
14.0
30
36
Q25.21
ICD-10 Finland
Interrupted aortic arch
+∞
13.5
13
*
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
+∞
13.5
13
*
I37.0
ICD-10 Finland
Pulmonary valve stenosis
+∞
13.5
13
*
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
+∞
13.5
13
*
Q25.70
ICD-10 Finland
Aneurysm, congenital of pulmonary artery
+∞
13.5
13
*
FJE42
NOMESCO Finland
Percutaneous transluminal expansion of pulmonary valve
+∞
13.5
13
*
Q21.21
ICD-10 Finland
Atrioventricular duct
+∞
13.5
13
*
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
13.5
13
*
1EA01
NOMESCO Finland
NA
140.6
13.4
14
*
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
6.5
13.2
34
54
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
10.6
13.2
25
24
K84
ICPC
Heart disease other
8.9
13.0
27
31
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
12.8
155
805
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
70.2
12.5
14
*
Q20.00
ICD-10 Finland
Common arterial trunk
+∞
12.5
12
*
FAE10
NOMESCO Finland
Bidirectional anastomosis between superior vena cava and pulmonary artery
+∞
12.5
12
*
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
+∞
12.5
12
*
FBA96
NOMESCO Finland
Other suture or repair of pulmonary artery
+∞
12.5
12
*
FXA13
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and exclusive cerebral perfusion
+∞
12.5
12
*
FLE96
NOMESCO Finland
Other repair of outlet obstruction of left ventricle
+∞
12.5
12
*
Q25.4
ICD-10 Finland
Other congenital malformations of aorta
+∞
12.5
12
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
4.5
12.4
44
102
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
8.5
12.2
26
31
602
Kela drug reimbursment
Children's severe malnutrition
4.0
12.1
48
124
C09AA05
ATC
ramipril; oral
2.6
12.1
91
372
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
12.0
148
770
JDB10
NOMESCO Finland
Percutaneous gastrostomy
7.6
11.9
27
36
207
Kela drug reimbursment
Chronic arrhythmias
3.2
11.7
61
197
I44.2
ICD-10 Finland
Atrioventricular block, complete
9.7
11.7
23
24
7AX01
NOMESCO Finland
NA
19.0
11.5
17
9
RK260
NOMESCO Finland
NA
23.0
11.5
16
7
Q25.45
ICD-10 Finland
Congenital aortic aneurysm
+∞
11.4
11
*
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
+∞
11.4
11
*
I28.8
ICD-10 Finland
Other specified diseases of pulmonary vessels
+∞
11.4
11
*
AJ1
HP
Reconstruction of the aortic base, eg composite graft, incl. valve saving operation
120.2
11.4
12
*
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.9
11.3
192
1135
J01CA04
ATC
amoxicillin; systemic
2.1
11.1
625
5425
FCA50
NOMESCO Finland
Resection and reconstruction of ascending aorta using tube graft
43.4
10.9
13
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.6
10.8
48
137
R50.9
ICD-10 Finland
Fever, unspecified
2.0
10.6
161
907
B01AB05
ATC
enoxaparin; parenteral
2.1
10.6
130
673
C09AA02
ATC
enalapril; systemic
2.5
10.5
85
361
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
+∞
10.4
10
*
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
+∞
10.4
10
*
21
HP
Aortic Valve Replacement (AVR)
+∞
10.4
10
*
FJD20
NOMESCO Finland
Bypass of pulmonary valve with ventriculopulmonary prosthesis or homograft
+∞
10.4
10
*
FBE96
NOMESCO Finland
Other expansion or reconstruction of pulmonary artery
+∞
10.4
10
*
FPH00
NOMESCO Finland
Transvenous extraction of transvenous cardiac pacemaker or cardioverter-defibrillator
110.0
10.4
11
*
FCC45
NOMESCO Finland
Percutaneous insertion of stent into descending aorta
110.0
10.4
11
*
AP3
HP
Catheterization of the right and left side of the heart
32.6
10.3
13
*
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
18.8
10.2
15
8
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
18.8
10.2
15
8
ZX120
NOMESCO Finland
Intravenous
2.5
10.1
83
356
C07AA07
ATC
sotalol; systemic
6.3
10.1
26
42
FM1CD
NOMESCO Finland
Very extensive CT of heart
40.1
9.9
12
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
9.9
154
877
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
9.6
9.7
19
20
R62.0
ICD-10 Finland
Delayed milestone
3.0
9.7
57
201
81
HP
Angiography of the heart and coronary arteries
4.9
9.6
30
62
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
9.1
9.5
19
21
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
6.7
9.4
23
35
FCA75
NOMESCO Finland
Valve-sparing repair of aortic root (David, Yacoub)
99.9
9.4
10
*
5609
FHL
Other measure in this category
+∞
9.3
9
*
7463A
ICD-9 Finland
Other congenital anomalies of heart, Congenital stenosis of aortic valve[STENOSIS VALVULAE AORTAE CONGENITA]
+∞
9.3
9
*
FMA20
NOMESCO Finland
Plastic repair of aortic valve for stenosis
+∞
9.3
9
*
FHE30
NOMESCO Finland
Repair of tetralogy of Fallot with transannular patch
+∞
9.3
9
*
Q20.40
ICD-10 Finland
Double inlet left ventricle
+∞
9.3
9
*
FMD40
NOMESCO Finland
Replacement of aortic root using pulmonary autograft and reimplantation of coronary arteries (Ross)
+∞
9.3
9
*
Q21.31
ICD-10 Finland
Tetralogy of Fallot and double outlet right ventricle
+∞
9.3
9
*
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
+∞
9.3
9
*
Q24.9
ICD-10 Finland
Congenital malformation of heart, unspecified
+∞
9.3
9
*
Q24.0
ICD-10 Finland
Dextrocardia
+∞
9.3
9
*
WZC30
NOMESCO Finland
Teaching
2.3
9.2
87
401
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
6.3
9.0
23
37
TJD20
NOMESCO Finland
Change of gastrostomy tube
5.9
9.0
24
41
F83
ICD-10 Finland
Mixed specific developmental disorders
3.1
9.0
48
159
FM1BD
NOMESCO Finland
Extensive CT of heart
36.7
9.0
11
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.4
8.9
73
313
I47.2
ICD-10 Finland
Ventricular tachycardia
8.6
8.7
18
21
ZX199
NOMESCO Finland
Other rote
6.6
8.6
21
32
AN1
HP
Coronary angiography
3.1
8.6
46
153
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
4.4
8.6
30
70
3A019
NOMESCO Finland
NA
11.6
8.5
15
13
PD5CD
NOMESCO Finland
Very extensive CT angiography of aorta
27.5
8.4
11
*
90492
NOMESCO Finland
NA
89.8
8.4
9
*
GAB00
NOMESCO Finland
Emergency thoracotomy
+∞
8.3
8
*
Q22.5
ICD-10 Finland
Ebstein anomaly
+∞
8.3
8
*
74699
ICD-8 Finland
Congenital anomalies of heart, Unspecified anomalies of heart
+∞
8.3
8
*
Q25.43
ICD-10 Finland
(Ruptured) aneurysm of sinus Valsalva
+∞
8.3
8
*
FCC50
NOMESCO Finland
Resection and reconstruction of descending aorta using tube graft
+∞
8.3
8
*
5207
FHL
VSD closure
+∞
8.3
8
*
PD5CM
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aorta with 3 Tesla magnet
+∞
8.3
8
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.1
8.3
44
146
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
8.1
122
682
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.9
8.0
47
166
Q90.0
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
33.3
8.0
10
*
WX870
NOMESCO Finland
Other postsurgical intensive care
11.7
8.0
14
12
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
8.0
189
1226
324
NOMESCO Finland
NA
22.0
8.0
11
5
3A077
NOMESCO Finland
NA
22.0
8.0
11
5
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
3.0
7.9
45
156
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
4.7
7.8
25
54
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
7.0
7.7
18
26
FC1BC
NOMESCO Finland
Extensive angiography of thoracal aortta
44.8
7.7
9
*
AB1
HP
AVR mechanical
44.8
7.7
9
*
1CX08
NOMESCO Finland
NA
15.0
7.7
12
8
Z31.5
ICD-10 Finland
Genetic counselling
2.4
7.7
67
296
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
5.0
7.5
23
47
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.8
7.5
47
172
5253
FHL
Cardiac lung machine
79.8
7.4
8
*
ZF61V
NOMESCO Finland
NA
79.8
7.4
8
*
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.1
7.3
81
400
FAE30
NOMESCO Finland
Total cavo-pulmonary connection using fenestrated patch
+∞
7.3
7
*
74619
ICD-8 Finland
Congenital anomalies of heart, Transposition of great vessels
+∞
7.3
7
*
Q23.20
ICD-10 Finland
Congenital mitral stenosis
+∞
7.3
7
*
FDJ30
NOMESCO Finland
Reconstruction of aorta for coarctation using tube graft
+∞
7.3
7
*
5512
FHL
Cleavage or ligation of the ductus arteriosus
+∞
7.3
7
*
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
+∞
7.3
7
*
Q25.5
ICD-10 Finland
Atresia of pulmonary artery
+∞
7.3
7
*
74673
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae aortae
+∞
7.3
7
*
FBE00
NOMESCO Finland
Expansion of pulmonary artery
+∞
7.3
7
*
FDE96
NOMESCO Finland
Other closure of patent ductus arteriosus
+∞
7.3
7
*
74659
ICD-8 Finland
Congenital anomalies of heart, Maleformatio valvulae mitralis
+∞
7.3
7
*
I37.2
ICD-10 Finland
Pulmonary valve stenosis with insufficiency
+∞
7.3
7
*
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
10.9
7.2
13
12
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
4.2
7.2
26
63
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.7
7.2
172
1113
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.8
7.2
44
161
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
15.7
7.2
11
7
J21.9
ICD-10 Finland
Acute bronchiolitis, unspecified
2.9
7.1
42
150
I97.0
ICD-10 Finland
Postcardiotomy syndrome
29.9
7.1
9
*
R06.0
ICD-10 Finland
Dyspnoea
1.8
7.1
122
715
XG460
NOMESCO Finland
Short time oxymetry
6.0
7.0
18
30
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
8.8
7.0
14
16
C07AB03
ATC
atenolol; systemic
4.0
6.9
26
66
B34.9
ICD-10 Finland
Viral infection, unspecified
2.4
6.9
55
234
C08CA02
ATC
felodipine; oral
3.2
6.9
34
108
J45.1
ICD-10 Finland
Nonallergic asthma
2.1
6.9
78
390
I27.0
ICD-10 Finland
Primary pulmonary hypertension
39.9
6.7
8
*
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
3.0
6.6
35
117
I35.9
ICD-10 Finland
Aortic valve disorder, unspecified
22.4
6.6
9
*
Q90.9
ICD-10 Finland
Down syndrome, unspecified
22.4
6.6
9
*
RS221
NOMESCO Finland
NA
3.5
6.6
29
85
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
6.5
119
707
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
12.2
6.5
11
9
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
69.5
6.4
7
*
Q90
ICD-10 Finland
Down syndrome
69.5
6.4
7
*
Q87.06
ICD-10 Finland
Velocardiofacial syndrome
69.5
6.4
7
*
AJ2
HP
Reconstruction of the ascending aorta
69.5
6.4
7
*
I49.3
ICD-10 Finland
Ventricular premature depolarization
3.1
6.4
33
109
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.2
6.4
66
317
TFJ02
NOMESCO Finland
Muscle biopsy of heart
11.0
6.3
11
10
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
+∞
6.2
6
*
FBJ00
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery
+∞
6.2
6
*
PD5DM
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aorta with 3 Tesla magnet
+∞
6.2
6
*
FDA96
NOMESCO Finland
Other operation for HLHS
+∞
6.2
6
*
FLE10
NOMESCO Finland
Myotomy or myectomy of left ventricle for outlet obstruction
+∞
6.2
6
*
FAE96
NOMESCO Finland
Other connection to pulmonary artery from superior vena cava
+∞
6.2
6
*
Q26.3
ICD-10 Finland
Partial anomalous pulmonary venous connection
+∞
6.2
6
*
7454A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM NUD]
+∞
6.2
6
*
74729
ICD-8 Finland
Other congenital anomalies of circulatory system, Maleformationes aortae aliae
+∞
6.2
6
*
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
+∞
6.2
6
*
Q23.9
ICD-10 Finland
Congenital malformation of aortic and mitral valves, unspecified
+∞
6.2
6
*
FDH10
NOMESCO Finland
Reconstruction of interrupted or hypoplastic aortic arch using patch
+∞
6.2
6
*
FMC20
NOMESCO Finland
Suture of leaflet of aortic valve
+∞
6.2
6
*
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
+∞
6.2
6
*
Q21.20
ICD-10 Finland
Atrial septal defect of primum type
+∞
6.2
6
*
FLE00
NOMESCO Finland
Excision of subvalvular membrane of left ventricle
+∞
6.2
6
*
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
+∞
6.2
6
*
AF1
HP
Surgery of congenital heart defect
+∞
6.2
6
*
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
26.5
6.2
8
*
PD5AD
NOMESCO Finland
CT of aorta
7.0
6.2
14
20
WX002
NOMESCO Finland
Sedation and analgesia
1.8
6.1
101
582
I47.1
ICD-10 Finland
Supraventricular tachycardia
2.9
6.1
35
123
Z94.1
ICD-10 Finland
Heart transplant status
8.6
6.0
12
14
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
423
900
8.73
210.03
7.6
3.5
1170.2
1061.8
ng/l
0.23
397
738
233
249
12.58
202.58
5.0
5.1
193.6
200.5
ng/l
0.06
213
224
337
1344
3.54
64.14
3.2
3.1
—
—
—
0
0
157
362
5.06
63.86
12.2
8.4
83.9
93.5
%
4.93
157
356
242
790
3.89
62.19
6.6
3.2
2544.2
362.1
ng/l
3.13
200
487
35
12
29.92
51.65
6.0
12.8
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
80
134
6.41
45.50
24.2
12.0
0.3
0.3
u/ml
0.07
50
82
443
2425
2.79
43.88
4.6
4.4
—
—
—
0
0
114
289
4.35
40.42
2.3
2.2
17.2
8.1
ug/l
2.99
108
249
228
912
3.04
40.28
11.3
10.0
0.8
0.8
mmol/l
0.90
223
869
119
392
3.33
28.51
61.0
15.8
2.4
1.3
inr
—
10
65
131
459
3.16
28.34
26.2
10.2
0.5
0.5
mmol/l
0.01
114
360
86
240
3.82
26.44
33.2
13.6
—
—
—
0
0
736
6007
3.74
23.52
25.4
14.3
139.4
139.5
mmol/l
0.59
726
5840
734
6009
3.60
22.72
25.2
14.4
4.0
4.0
mmol/l
1.36
723
5817
60
144
4.34
22.58
1.4
1.4
—
—
—
0
0
495
3462
2.07
21.18
13.4
6.8
6.2
6.3
mmol/l
0.97
469
3212
179
850
2.38
20.96
3.0
2.9
2.5
2.5
g/l
0.21
173
804
170
796
2.40
20.51
3.0
3.0
21.1
22.7
%
0.94
156
739
400
2612
2.01
20.48
9.6
7.9
23.4
19.1
umol/l
1.31
378
2455
220
1175
2.16
19.24
12.8
10.8
1.3
1.3
mmol/l
0.32
214
1119
245
1387
2.06
18.23
4.0
3.0
71.6
33.0
ng/l
1.37
159
785
171
848
2.25
17.84
2.2
2.1
—
—
—
0
0
138
656
2.29
15.79
2.1
2.0
—
—
—
0
0
138
661
2.27
15.49
2.2
2.1
—
—
—
0
0
208
1172
2.01
15.30
4.6
3.4
1.9
1.5
mg/l
0.50
146
881
225
1340
1.91
13.89
3.2
2.5
437.0
311.9
u/l
0.84
218
1277
397
2842
1.74
13.08
21.3
11.7
1.2
1.2
mmol/l
10.32
384
2682
200
1171
1.90
12.88
9.5
10.4
1.4
1.2
mmol/l
0.39
164
922
290
1918
1.76
12.48
4.6
4.7
42.1
33.3
u/l
1.04
283
1832
729
6367
2.50
11.97
19.1
12.3
27.8
23.0
mg/l
3.10
593
4611
410
3030
1.68
11.47
16.7
11.4
1.2
1.2
mmol/l
5.66
372
2740
189
1130
1.84
11.23
14.2
10.4
5.2
5.0
kpa
3.58
184
1079
187
1116
1.84
11.17
14.2
10.4
2.0
0.7
mmol/l
12.16
160
774
236
1547
1.71
10.08
3.1
3.0
3.1
2.8
mg/l
1.45
212
1362
306
2152
1.64
9.97
9.1
7.4
36.1
36.9
g/l
1.19
291
2047
504
4025
1.63
9.62
7.7
6.7
100.1
106.3
u/l
0.98
482
3780
304
2214
1.56
8.16
3.9
4.3
—
—
—
0
0
164
1027
1.72
8.07
8.8
10.3
23.9
23.6
mmol/l
0.87
159
986
43
162
2.70
8.05
2.2
3.9
—
—
—
0
0
526
4337
1.56
7.95
14.2
9.7
92.9
93.1
ml/min/173m2
0.05
433
3257
680
5980
1.81
7.91
26.1
16.4
13.5
13.4
%
3.10
673
5897
55
237
2.37
7.81
2.2
2.2
—
—
—
0
0
43
168
2.60
7.51
1.7
2.1
—
—
—
0
0
54
238
2.32
7.30
2.2
2.3
—
—
—
0
0
45
184
2.49
7.17
1.5
2.0
—
—
—
0
0
41
164
2.53
6.84
2.2
3.9
12.3
9.0
%
0.90
32
150
492
4079
1.48
6.59
10.5
11.5
3.9
3.6
e9/l
1.82
440
3426
13
26
4.98
6.08
1.5
1.4
24210.0
22122.5
e6/l
—
8
16
14
30
4.65
6.07
1.9
1.2
—
—
—
0
0
49
226
2.20
5.99
1.7
1.4
—
—
—
0
0
49
226
2.20
5.99
1.7
1.4
—
—
—
0
0
189
1316
1.54
5.89
2.9
3.3
4.6
5.4
e6/l
0.45
172
1139
38
160
2.40
5.73
1.6
2.0
—
—
—
0
0
42
186
2.29
5.66
1.6
2.1
1.3
1.3
g/l
0.05
27
162
368
2945
1.42
5.56
3.8
3.2
79.7
80.6
ug/l
0.05
352
2777
139
916
1.59
5.48
1.5
1.4
23.5
21.2
nmol/l
0.85
123
789
253
1894
1.46
5.48
3.5
4.1
0.2
0.3
e6/l
0.78
202
1394
64
338
1.93
5.47
3.2
2.6
70.1
74.6
ml/min/173m2
0.31
27
125
127
834
1.59
5.07
5.5
6.0
9.2
7.2
umol/l
0.80
116
696
772
7259
2.53
4.92
29.2
18.1
246.3
263.9
e9/l
11.03
757
6962
59
315
1.91
4.90
3.2
5.0
1.2
1.2
mmol/l
0.26
54
277
205
1513
1.45
4.68
3.5
2.9
59.9
56.4
u/l
0.56
191
1406
22
78
2.82
4.68
2.2
1.7
—
—
—
0
0
772
7271
2.47
4.68
31.1
18.2
132.4
134.9
g/l
4.01
765
7186
18
57
3.15
4.64
1.8
2.1
—
—
—
0
0
9
11
8.11
4.51
2.8
4.0
—
—
—
0
0
16
48
3.32
4.48
4.3
2.8
4.1
4.0
mmol/l
0.07
16
48
10
21
4.72
4.43
1.9
1.6
—
—
—
0
0
63
356
1.80
4.41
2.2
1.8
—
—
—
0
0
110
725
1.57
4.32
1.8
1.6
459.5
18367805.4
pmol/l
0.79
96
637
57
315
1.84
4.29
1.7
1.8
—
—
—
0
0
14
40
3.48
4.22
1.1
1.1
85.8
91.4
%
—
9
19
28
120
2.34
4.12
1.9
1.5
—
—
—
0
0
15
47
3.18
3.94
4.5
2.8
105.3
106.1
mmol/l
0.26
15
47
85
540
1.61
3.90
7.5
7.6
66.1
58.2
ng/l
0.65
77
518
25
105
2.38
3.86
4.6
2.9
18.1
17.4
%
0.31
14
65
13
38
3.40
3.80
1.2
1.2
—
—
—
0
0
188
1414
1.40
3.79
4.4
3.5
0.0
0.0
estimate
0.88
67
489
439
3764
1.32
3.71
4.4
4.1
8.6
82.7
e6/l
—
5
42
23
95
2.42
3.69
2.2
1.6
—
—
—
0
0
13
39
3.31
3.66
1.4
1.1
69.4
90.2
%
—
8
18
33
169
1.96
3.17
2.0
3.6
0.2
0.2
e9/l
0.76
26
121
12
38
3.13
3.12
1.5
1.6
—
—
—
0
0
25
117
2.13
3.05
2.3
4.2
57.5
52.7
%
1.08
25
117
681
6305
1.42
3.05
11.9
9.9
28.3
27.2
u/l
0.51
663
6110
62
391
1.60
2.97
3.3
2.9
—
—
—
0
0
149
1126
1.37
2.88
4.2
3.9
3763.4
3479.3
umol/l
0.03
131
1015
27
135
2.00
2.80
4.2
2.5
141.5
134.9
g/l
0.41
18
105
33
178
1.86
2.76
1.4
1.6
—
—
—
0
0
22
103
2.13
2.71
3.0
3.5
21.1
28.9
mg/l
0.59
16
62
82
563
1.48
2.70
1.7
1.6
1122.8
1188.9
nmol/l
0.26
66
431
32
172
1.86
2.70
2.1
3.6
379.0
575.4
e6/l
2.14
26
122
45
697
0.61
2.65
1.0
1.1
—
—
—
0
0
22
104
2.11
2.65
1.3
1.2
1.6
2.7
u/ml
—
8
45
29
153
1.89
2.60
1.9
2.0
—
—
—
0
0
22
105
2.09
2.59
1.2
1.2
4.4
3.2
u/ml
0.22
14
54
23
112
2.05
2.57
3.7
5.5
5.0
4.9
kpa
0.37
23
112
417
3656
1.25
2.55
4.1
4.1
47.9
39.4
u/l
1.47
391
3496
13
49
2.63
2.54
1.6
2.3
31.7
33.3
pg
0.76
13
49
690
6448
1.39
2.50
27.7
15.1
39.1
39.7
%
1.64
596
5484
27
142
1.90
2.45
1.9
1.8
—
—
—
0
0
26
137
1.89
2.36
2.6
1.5
—
—
—
0
0
53
352
1.51
2.09
3.4
3.6
4.6
4.9
pmol/l
1.69
48
321
22
116
1.89
2.02
2.3
3.7
4.2
3.8
e9/l
0.36
22
116
153
1222
1.28
2.01
3.2
3.6
0.7
0.8
e6/l
0.29
90
700
331
2886
1.22
1.97
3.9
3.4
0.0
0.0
estimate
0.80
72
486
15
69
2.16
1.97
1.1
1.2
—
—
—
0
0
15
69
2.16
1.97
1.1
1.2
—
—
—
0
0
328
2861
1.21
1.94
5.2
4.9
0.0
0.0
estimate
0.50
72
508
62
434
1.44
1.91
9.5
6.1
—
—
—
0
0
8
27
2.93
1.90
1.4
1.6
—
—
—
0
0
326
2849
1.21
1.87
3.9
3.4
0.0
0.0
estimate
0.00
67
479
20
105
1.89
1.87
1.1
1.1
—
—
—
0
0
508
4634
1.21
1.85
3.9
3.7
14.9
14.5
pmol/l
2.86
477
4271
40
259
1.54
1.80
3.4
3.7
0.1
0.1
e6/l
0.21
40
251
12
238
0.49
1.73
1.0
1.1
4.2
0.4
u/ml
—
6
113
20
109
1.82
1.69
3.5
4.6
26.7
25.3
umol/l
0.40
20
109
148
1207
1.25
1.64
3.4
3.8
2.8
1.9
e6/l
0.41
86
693
20
333
0.58
1.64
1.9
1.4
—
—
—
0
0
206
2329
0.82
1.63
1.5
1.7
1.1
2.9
u/ml
3.01
43
432
20
111
1.79
1.61
1.6
2.0
—
—
—
0
0
36
518
0.67
1.59
1.5
1.5
—
—
—
0
0
14
69
2.01
1.58
1.1
1.2
—
—
—
0
0
7
26
2.66
1.55
1.0
1.6
0.9
1.1
g/l
—
7
26
519
4789
1.19
1.49
4.3
3.8
4.4
4.6
mmol/l
5.33
500
4528
6
21
2.82
1.47
1.5
1.6
—
—
—
0
0
193
1644
1.20
1.41
3.4
3.3
2.4
2.4
mmol/l
1.21
181
1488
235
2038
1.19
1.41
4.0
3.2
—
—
—
0
0
32
210
1.52
1.40
11.1
10.8
254.4
467.3
iu/ml
—
5
35
495
4562
1.17
1.40
3.9
3.4
1.3
1.2
mmol/l
0.30
475
4287
0
38
0.00
1.34
0.0
1.2
—
—
—
0
0
6
23
2.57
1.34
1.5
1.5
—
—
—
0
0
9
42
2.12
1.31
1.2
1.9
12.8
10.3
umol/l
—
9
42
23
142
1.61
1.31
1.7
1.8
—
—
—
0
0
8
34
2.32
1.28
1.8
3.3
—
—
—
0
0
13
69
1.86
1.23
1.1
1.2
—
—
—
0
0
13
69
1.86
1.23
1.1
1.2
—
—
—
0
0
22
329
0.65
1.21
2.4
1.8
—
—
—
0
0
13
70
1.84
1.18
4.9
5.3
—
—
—
0
0
0
32
0.00
1.16
0.0
1.2
—
—
—
0
0
0
34
0.00
1.16
0.0
1.6
—
2.1
—
0
19
31
428
0.70
1.15
1.1
1.2
3.3
4.5
u/ml
0.27
12
145
43
315
1.36
1.10
1.7
1.9
—
—
—
0
0
54
413
1.30
1.05
2.2
2.4
5646.8
4259.9
u/l
0.12
20
143
28
194
1.43
1.00
1.2
1.2
—
—
—
0
0
21
138
1.51
0.96
3.9
2.4
—
—
—
0
0
34
249
1.36
0.90
4.3
3.8
30.8
36.8
umol/l
1.66
34
226
5
103
0.47
0.89
1.0
1.2
0.0
16.4
u/ml
—
5
94
41
310
1.32
0.89
1.8
1.4
—
—
—
0
0
218
2343
0.88
0.86
2.0
1.9
—
—
—
0
0
187
1655
1.14
0.85
2.1
1.7
91.3
96.7
pmol/l
0.89
108
840
18
257
0.68
0.84
1.2
1.5
—
—
—
0
0
12
71
1.67
0.84
1.2
1.5
5.5
7.3
mmol/l
—
7
49
511
4807
1.12
0.84
4.6
4.0
2.6
2.8
mmol/l
2.88
490
4495
10
56
1.76
0.83
3.0
1.3
—
—
—
0
0
504
4743
1.12
0.81
4.1
3.7
1.4
1.4
mmol/l
1.47
485
4453
14
208
0.65
0.80
2.9
2.2
0.7
0.6
nmol/l
0.25
14
181
35
443
0.77
0.80
1.4
1.2
—
—
—
0
0
0
24
0.00
0.79
0.0
1.5
—
—
—
0
0
104
1171
0.85
0.79
2.4
2.2
—
—
—
0
0
6
33
1.79
0.77
5.2
5.1
—
—
—
0
0
31
396
0.76
0.76
1.2
1.2
—
—
—
0
0
75
623
1.20
0.76
2.6
2.1
—
—
—
0
0
72
833
0.83
0.75
4.0
3.7
23.8
21.5
%
0.49
35
343
5
23
2.14
0.75
1.4
1.3
—
—
—
0
0
5
23
2.14
0.75
1.4
1.3
—
—
—
0
0
5
23
2.14
0.75
2.0
1.2
364.4
384.4
u/l
—
5
23
98
835
1.17
0.75
1.2
1.2
27.1
28.7
iu/ml
0.06
20
237
496
4674
1.11
0.75
4.0
3.4
5.6
5.7
mmol/l
0.66
460
4298
29
372
0.76
0.74
1.3
1.3
—
—
—
0
0
25
181
1.37
0.74
1.3
1.3
276.3
350.1
ug/g
0.87
15
101
6
105
0.56
0.73
1.0
1.3
1.7
8.1
u/ml
—
6
95
7
38
1.82
0.73
1.3
1.6
—
—
—
0
0
20
271
0.72
0.73
1.0
1.0
-1.9
-2.5
mmol/l
—
6
68
20
271
0.72
0.73
1.0
1.0
7.2
7.3
kpa
0.06
20
235
20
271
0.72
0.73
1.0
1.0
20.2
19.5
mmol/l
0.67
20
266
15
99
1.50
0.71
1.9
1.3
—
—
—
0
0
148
1311
1.13
0.68
4.3
3.2
1.0
1.0
kg/l
0.21
18
228
28
210
1.32
0.67
1.3
2.6
—
—
—
0
0
20
267
0.73
0.67
1.0
1.0
3.1
3.3
kpa
0.53
20
232
39
473
0.80
0.66
1.2
1.3
1.4
2.7
u/ml
0.44
20
313
17
232
0.71
0.66
1.4
1.4
—
—
—
0
0
17
232
0.71
0.66
1.4
1.4
—
—
—
0
0
13
85
1.51
0.64
3.0
1.2
—
—
—
0
0
17
231
0.72
0.64
1.4
1.4
—
—
—
0
0
17
231
0.72
0.64
1.1
1.1
—
—
—
0
0
17
231
0.72
0.64
1.4
1.4
—
—
—
0
0
7
44
1.57
0.64
1.9
3.0
33.5
3.0
nmol/l
—
7
44
0
21
0.00
0.60
0.0
1.6
—
—
—
0
0
17
227
0.73
0.59
3.2
2.4
30.6
35.5
u/ml
0.15
17
216
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
19
248
0.75
0.57
1.4
1.4
2.7
3.4
mg/l
—
10
172
14
97
1.42
0.55
2.0
1.3
—
—
—
0
0
568
5433
1.09
0.53
4.7
4.2
2.0
1.9
mu/l
0.73
535
5063
265
2463
1.08
0.49
3.8
3.2
75.3
72.2
nmol/l
1.04
244
2297
52
441
1.17
0.47
2.5
2.0
6.3
6.7
u/l
0.13
41
280
8
117
0.67
0.46
1.1
1.4
—
—
—
0
0
20
249
0.78
0.45
1.1
1.1
3.4
9.9
u/ml
3.01
13
148
10
138
0.71
0.44
1.2
1.3
—
—
—
0
0
14
102
1.35
0.43
1.1
1.8
5.0
3.6
umol/l
0.87
14
93
22
267
0.80
0.42
1.1
1.1
13.4
9.0
u/ml
0.28
14
153
5
32
1.54
0.41
1.0
1.2
219.0
609.0
u/l
—
5
26
78
689
1.12
0.41
2.4
2.6
2.4
2.4
mmol/l
1.17
64
587
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
75
818
0.89
0.41
1.3
1.2
15.6
7.6
u/ml
0.36
29
293
12
86
1.38
0.41
2.4
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
3.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
523.7
—
0
9
0
18
0.00
0.40
0.0
1.1
—
40.8
—
0
8
145
1327
1.09
0.39
1.9
1.8
1.4
1.3
mmol/l
0.44
132
1165
84
748
1.11
0.39
2.8
2.2
—
—
—
0
0
19
148
1.27
0.39
3.5
1.7
—
—
—
0
0
452
4314
1.07
0.39
5.3
4.7
37.2
38.5
mmol/mol
2.43
429
4068
16
122
1.29
0.38
1.3
1.3
—
1.2
—
0
7
26
212
1.21
0.37
1.2
1.1
—
—
—
0
0
5
76
0.64
0.36
1.0
1.3
—
—
—
0
0
5
78
0.63
0.35
1.6
1.8
—
—
—
0
0
6
43
1.37
0.34
1.5
1.3
—
—
—
0
0
14
174
0.79
0.33
1.1
1.3
—
—
—
0
0
26
215
1.19
0.33
1.2
1.1
—
—
—
0
0
6
46
1.28
0.32
1.3
1.5
—
—
—
0
0
73
784
0.91
0.32
1.3
1.5
—
—
—
0
0
7
51
1.35
0.31
1.0
1.8
—
—
—
0
0
7
51
1.35
0.31
1.0
1.8
—
—
—
0
0
7
51
1.35
0.31
1.0
1.8
—
—
—
0
0
19
225
0.83
0.31
1.3
4.2
9.8
7.2
e6/l
0.14
13
162
19
225
0.83
0.31
1.4
4.3
7106.0
996.2
e6/l
0.46
14
167
7
53
1.30
0.30
1.0
1.3
—
—
—
0
0
56
497
1.11
0.30
1.4
1.3
126.5
151.6
iu/ml
0.17
18
169
38
329
1.14
0.29
3.7
4.4
13.6
20.9
ug/l
0.17
27
258
8
105
0.75
0.29
1.3
1.6
—
—
—
0
0
8
61
1.29
0.28
1.1
1.3
—
—
—
0
0
122
1271
0.93
0.28
2.4
2.4
—
—
—
0
0
60
538
1.10
0.27
2.6
2.2
11.0
12.3
nmol/l
0.52
52
450
448
4305
1.05
0.27
5.0
4.4
10.3
8.9
mm/h
1.34
426
4015
50
447
1.11
0.24
2.6
2.0
15.6
13.6
iu/l
0.26
42
308
6
80
0.73
0.24
1.2
4.1
—
—
—
0
0
6
80
0.73
0.24
1.2
4.1
—
—
—
0
0
33
362
0.89
0.23
1.8
1.8
—
—
—
0
0
5
39
1.26
0.22
1.2
1.0
—
—
—
0
0
15
123
1.20
0.22
1.1
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
5.9
—
0
5
0
10
0.00
0.21
0.0
16.0
—
—
—
0
0
0
11
0.00
0.21
0.0
19.7
—
—
—
0
0
0
11
0.00
0.21
0.0
19.8
—
24.3
—
0
11
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
5.6
—
3.6
—
0
12
5
42
1.17
0.21
7.0
8.8
—
—
—
0
0
6
47
1.26
0.20
1.0
1.2
226.2
201.9
iu/ml
—
6
47
0
14
0.00
0.20
0.0
1.4
—
316.4
—
0
8
6
51
1.16
0.19
3.0
7.2
—
—
—
0
0
6
51
1.16
0.19
4.3
7.3
—
—
—
0
0
6
51
1.16
0.19
1.2
1.2
—
—
—
0
0
14
116
1.19
0.19
1.1
1.9
—
—
—
0
0
6
52
1.13
0.18
1.2
1.2
—
—
—
0
0
23
253
0.89
0.17
1.1
1.3
335.6
247.5
miu/ml
—
9
130
12
139
0.85
0.17
1.5
1.8
140.6
217.9
pmol/l
1.71
12
131
5
68
0.72
0.17
1.0
1.1
—
—
—
0
0
8
67
1.17
0.16
1.0
1.3
—
—
—
0
0
8
71
1.11
0.16
1.1
1.3
—
—
—
0
0
578
5621
1.04
0.15
3.7
3.8
—
—
—
0
0
58
604
0.94
0.15
3.0
2.6
1.2
0.7
ug/l
0.79
35
354
7
85
0.81
0.14
1.0
1.1
—
—
—
0
0
7
85
0.81
0.14
1.0
1.1
—
—
—
0
0
45
471
0.93
0.14
1.3
1.5
—
—
—
0
0
42
438
0.94
0.12
3.8
3.6
32.4
31.9
%
0.11
33
310
58
598
0.95
0.12
3.4
2.4
29.7
31.5
u/l
0.20
53
492
38
350
1.07
0.11
2.5
2.0
229.5
175.7
u/ml
0.47
23
166
21
224
0.92
0.10
1.3
1.6
—
—
—
0
0
5
44
1.12
0.10
31.8
19.5
1571.0
1484.6
nmol/l
—
5
44
5
46
1.07
0.09
1.0
1.3
2.0
1.2
nmol/l
—
5
40
5
47
1.04
0.09
3.4
1.9
607.4
1188.3
u/ml
—
5
47
19
171
1.09
0.09
1.6
1.9
—
—
—
0
0
22
200
1.08
0.09
1.5
1.7
36.2
39.1
nmol/l
0.24
22
195
38
354
1.06
0.09
2.4
2.0
—
—
—
0
0
173
1667
1.02
0.08
4.0
4.2
7.0
8.1
mmol/l
2.22
158
1480
5
60
0.82
0.08
1.0
1.1
—
—
—
0
0
5
61
0.80
0.08
7.4
10.0
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
8
76
1.03
0.07
1.0
1.3
—
—
—
0
0
7
82
0.84
0.07
1.0
1.1
—
—
—
0
0
20
183
1.08
0.07
1.5
1.5
—
—
—
0
0
8
91
0.86
0.06
1.1
1.3
77.4
76.6
%
—
8
91
8
91
0.86
0.06
1.1
1.3
—
—
—
0
0
27
252
1.05
0.06
1.3
1.3
—
—
—
0
0
10
108
0.91
0.05
2.3
2.0
—
—
—
0
0
13
138
0.92
0.05
1.5
1.5
—
—
—
0
0
11
116
0.93
0.03
1.3
1.6
—
—
—
0
0
10
106
0.93
0.03
1.2
1.3
104.5
69.7
pmol/l
—
10
101
17
159
1.05
0.02
2.9
1.9
2.6
4.8
iu/l
—
8
54
112
1089
1.01
0.02
4.4
4.2
13.2
12.0
mg/mmol
0.07
77
745
31
312
0.97
0.01
1.5
1.4
—
—
—
0
0
10
96
1.02
0.00
1.2
1.1
—
—
—
0
0
19
189
0.99
0.00
2.1
1.8
—
—
—
0
0
107
1053
1.00
0.00
4.0
3.9
1.9
2.1
ug/l
0.26
96
957
21
210
0.98
0.00
1.7
1.7
—
—
—
0
0
11
104
1.04
0.00
1.4
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
74
0.93
0.00
1.0
1.3
—
—
—
0
0
7
69
1.00
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
227.3
—
0
6
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
9
92
0.96
0.00
1.4
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CONGEN_MALFO_GREAT_ARTERIES and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_GREAT_ARTERIES | 3.101 [2.4, 4.0] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.421 |
During the follow-up period (1.1.1998 — 31.12.2019), 246 out of 5292 females with Q17_CONGEN_MALFO_GREAT_ARTERIES died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_CONGEN_MALFO_GREAT_ARTERIES | 2.705 [2.21, 3.31] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 278 out of 5278 males with Q17_CONGEN_MALFO_GREAT_ARTERIES died.
Mortality risk
Mortality risk for people of age
years, who have Q17_CONGEN_MALFO_GREAT_ARTERIES.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.375% | 0.496% |
| 5 | 1.882% | 2.813% |
| 10 | 4.585% | 7.174% |
| 15 | 8.942% | 13.541% |
| 20 | 15.7% | 22.229% |
Relationships between endpoints
↥Index endpoint: Q17_CONGEN_MALFO_GREAT_ARTERIES – Congenital malformations of great arteries
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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