muscular disease: Acquired, familial, and congenital disorders of skeletal muscle and smooth muscle.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1264 |
4. Check minimum number of eventsNone |
1264 |
5. Include endpointsNone |
1264 |
6. Filter based on genotype QC (FinnGen only) |
1264 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M62
- Name in latin
- Distensio musculi
Similar endpoints
↥List of similar endpoints to
Muscle strain
based on the number of shared cases.
Similar with more cases:
- Disorders of muscles
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 11393 | 5255 | 6071 |
| Only index persons | 10885 | 5060 | 5825 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.15 | 0.17 |
| Only index persons | 0.21 | 0.19 | 0.22 |
| Median age at first event (years) | |||
| Whole population | 41.67 | 43.15 | 40.44 |
| Only index persons | 42.06 | 43.53 | 40.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1264 | 729 | 535 |
| Unadjusted period prevalence (%) | 0.24 | 0.25 | 0.24 |
| Median age at first event (years) | 50.13 | 48.08 | 52.93 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1124
- Matched controls
- 11240
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M62.6
ICD-10 Finland
Muscle strain
+∞
323.0
1124
68
M79.6
ICD-10 Finland
Pain in limb
4.5
102.6
472
1558
N02AJ06
ATC
codeine and paracetamol; systemic
2.8
51.9
477
2362
M75.1
ICD-10 Finland
Rotator cuff syndrome
3.8
47.6
232
727
N02AX02
ATC
tramadol; systemic, rectal
2.6
46.6
471
2423
M54.5
ICD-10 Finland
Low back pain
2.7
46.3
420
2029
M79.1
ICD-10 Finland
Myalgia
4.3
45.9
185
487
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.5
43.5
535
3033
N02BE01
ATC
paracetamol; systemic, rectal
2.9
41.1
959
7504
M25.5
ICD-10 Finland
Pain in joint
2.7
38.3
336
1554
M03BC01
ATC
orphenadrine (citrate); systemic
2.7
38.1
317
1424
R51.80
ICD-10 Finland
Headache
3.3
37.4
210
725
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.4
37.3
430
2303
R07.4
ICD-10 Finland
Chest pain, unspecified
2.7
36.8
305
1362
M03BX02
ATC
tizanidine; oral
2.2
36.5
715
4915
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.3
34.3
136
349
X59
ICD-10 Finland
Exposure to unspecified factor
2.8
33.7
247
1015
M01AH05
ATC
etoricoxib; oral
2.1
33.1
646
4342
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.5
32.3
326
1604
M54.4
ICD-10 Finland
Lumbago with sciatica
3.1
31.6
198
731
N03AX16
ATC
pregabalin; oral
2.7
31.6
244
1031
M01AB05
ATC
diclofenac; systemic, rectal
2.1
30.8
735
5305
N03AX12
ATC
gabapentin; oral
3.2
30.1
172
594
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
12.5
30.0
54
45
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.1
29.6
553
3583
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.5
29.1
275
1299
X58
ICD-10 Finland
Exposure to other specified factors
2.9
26.8
185
724
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
8.6
25.6
56
68
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.6
25.5
208
898
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.7
25.4
198
832
R03AC02
ATC
salbutamol; inhalant
1.9
25.3
581
3986
L17
ICPC
Foot/toe symptom/complaint
2.3
24.9
277
1406
A02BC02
ATC
pantoprazole; systemic
1.9
23.4
659
4809
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.0
23.2
141
505
S76.3
ICD-10 Finland
Injury of muscle and tendon of the posterior muscle group at thigh level
13.3
23.0
40
31
R06.0
ICD-10 Finland
Dyspnoea
2.3
22.9
250
1252
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
22.1
289
1567
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.6
21.8
102
301
M19.0
ICD-10 Finland
Primary arthrosis of other joints
4.1
21.6
87
225
J01DB01
ATC
cefalexin; oral
2.0
21.4
897
7431
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
20.9
258
1359
L03
ICPC
Low back symptom/complaint
2.1
20.0
269
1467
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
40.9
19.5
24
6
M79.0
ICD-10 Finland
Rheumatism, unspecified
18.6
19.2
29
16
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.9
19.1
124
463
M01AE03
ATC
ketoprofen; systemic, rectal
1.9
19.1
359
2222
L08
ICPC
Shoulder symptom/complaint
2.4
19.0
177
813
M01AC06
ATC
meloxicam; systemic, rectal
1.9
19.0
346
2117
M01AE01
ATC
ibuprofen; systemic, rectal
2.2
19.0
996
8727
L12
ICPC
Hand/finger symptom/complaint
2.5
18.9
162
710
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.7
18.7
135
539
G44.2
ICD-10 Finland
Tension-type headache
2.5
18.6
159
697
A02BC05
ATC
esomeprazole; systemic
1.9
18.6
394
2537
J01AA02
ATC
doxycycline; systemic
1.8
18.6
810
6577
L01
ICPC
Neck symptom/complaint
2.5
18.5
163
725
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
18.5
194
944
R42
ICD-10 Finland
Dizziness and giddiness
2.2
18.3
208
1049
M02AA07
ATC
piroxicam; topical
1.9
18.2
336
2058
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
18.1
264
1482
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
17.8
406
2673
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
3.6
17.6
81
236
P01AB01
ATC
metronidazole; oral, rectal
1.8
17.5
407
2691
H02AB06
ATC
prednisolone; systemic
1.8
17.4
458
3148
J01DA01
ATC
[U] cefalexin; systemic
1.7
17.4
655
5026
M70.6
ICD-10 Finland
Trochanteric bursitis
3.0
17.0
103
368
S18
ICPC
Laceration/cut
1.8
16.8
398
2644
Z71.8
ICD-10 Finland
Other specified counselling
1.9
16.7
271
1575
ZXA00
NOMESCO Finland
Right side
2.0
16.7
240
1335
M54.2
ICD-10 Finland
Cervicalgia
3.3
16.6
88
286
R52.9
ICD-10 Finland
Pain, unspecified
3.0
16.5
96
334
R05
ICPC
Cough
2.0
16.5
244
1371
M01AE02
ATC
naproxen; oral, rectal
1.7
16.4
603
4555
R74
ICPC
Upper respiratory infection acute
1.8
16.3
340
2158
A03
ICPC
Fever
2.1
16.3
204
1072
C07AB07
ATC
bisoprolol; oral
1.8
16.2
404
2716
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.2
16.2
187
945
M03BC51
ATC
orphenadrine, combinations; systemic
1.9
16.2
300
1828
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
16.1
522
3795
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
15.9
185
937
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
15.8
557
4140
R53
ICD-10 Finland
Malaise and fatigue
2.1
15.8
210
1130
J01CA04
ATC
amoxicillin; systemic
1.8
15.7
896
7668
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
15.5
773
6324
M54.6
ICD-10 Finland
Pain in thoracic spine
3.3
15.1
78
249
R50.9
ICD-10 Finland
Fever, unspecified
2.3
15.0
150
708
L13
ICPC
Hip symptom/complaint
2.3
14.9
144
670
J01FA10
ATC
azithromycin; systemic
1.7
14.9
639
4979
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.9
14.9
95
350
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
10.6
14.8
28
27
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.6
14.7
588
4487
R21
ICPC
Throat symptom/complaint
1.9
14.6
245
1432
S93.4
ICD-10 Finland
Sprain and strain of ankle
2.4
14.6
126
554
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
3.4
14.6
72
223
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.3
14.5
145
686
AA1AD
NOMESCO Finland
CT of head and brain
2.0
14.4
209
1157
SPAT1283
SPAT
Restricted health certificate
1.9
14.2
227
1306
W22
ICD-10 Finland
Striking against or struck by other object(s)
3.0
14.0
84
296
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.3
13.9
134
622
S22.3
ICD-10 Finland
Fracture of rib
3.2
13.9
73
237
J01FF01
ATC
clindamycin; systemic
1.8
13.8
264
1615
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
4.9
13.7
44
92
M67.4
ICD-10 Finland
Ganglion
4.4
13.5
49
116
ZXA05
NOMESCO Finland
Left side
1.9
13.5
216
1238
SPAT1153
SPAT
Removal of sutures
1.8
13.4
284
1794
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
13.0
13.4
23
18
NK1XE
NOMESCO Finland
Other ultrasound examinnation of muscle or tendon
13.0
13.4
23
18
N02AA05
ATC
oxycodone; systemic
2.4
13.4
118
522
D01
ICPC
Abdominal pain/cramps general
2.3
13.4
126
577
W19
ICD-10 Finland
Unspecified fall
2.5
13.4
104
432
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.1
13.3
159
814
M77.1
ICD-10 Finland
Lateral epicondylitis
3.1
13.3
73
245
R4110
NOMESCO Finland
Physiotherapy
1.8
13.1
252
1539
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.4
13.1
63
192
K02.1
ICD-10 Finland
Caries of dentine
1.6
13.0
623
4921
M01AH01
ATC
celecoxib; oral (coxibs)
2.1
13.0
157
807
L15
ICPC
Knee symptom/complaint
2.0
13.0
191
1063
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.7
13.0
91
356
M79.7
ICD-10 Finland
Fibromyalgia
7.8
12.9
29
38
J01FA06
ATC
roxithromycin; oral
1.7
12.9
390
2729
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.7
12.9
89
346
UJF32
NOMESCO Finland
Coloscopy
1.9
12.8
226
1341
WX110
NOMESCO Finland
Local anesthesy
1.6
12.8
736
6075
B01AB05
ATC
enoxaparin; parenteral
1.8
12.8
268
1683
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
12.8
304
1986
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
3.5
12.7
59
175
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
12.6
402
2850
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
3.4
12.6
61
187
L28
ICPC
Limited function/disability (L)
2.2
12.6
126
597
N06AX21
ATC
duloxetine; oral
2.4
12.6
105
454
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.2
12.5
139
690
Z00.0
ICD-10 Finland
General medical examination
1.9
12.5
189
1060
S89.9
ICD-10 Finland
Unspecified injury of lower leg
4.0
12.5
49
126
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.3
12.4
62
195
R03DC03
ATC
montelukast; oral
2.0
12.3
171
929
R02
ICPC
Shortness of breath/dyspnoea
2.3
12.3
114
520
R05FB02
ATC
cough suppressants and expectorants
1.7
12.3
350
2405
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
12.6
12.1
21
17
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.7
11.9
51
142
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.6
11.8
88
356
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
10.7
11.8
22
21
M65.3
ICD-10 Finland
Trigger finger
5.3
11.7
35
68
Z3226
NOMESCO Finland
Physiotherapist
1.9
11.6
175
977
M01AX17
ATC
nimesulide; oral
1.8
11.5
202
1195
ACC51
NOMESCO Finland
Release of median nerve
2.9
11.4
70
252
S06.0
ICD-10 Finland
Concussion
2.3
11.3
110
514
NBF25
NOMESCO Finland
Operation for humeroscapular osteochondritis, arthroscopic
9.7
11.3
22
23
M77.4
ICD-10 Finland
Metatarsalgia
3.6
11.0
49
141
R60.0
ICD-10 Finland
Localized oedema
2.5
11.0
89
379
L02
ICPC
Back symptom/complaint
2.3
10.9
102
464
M01AH02
ATC
rofecoxib; oral
2.3
10.9
105
489
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
10.8
145
777
Z3231
NOMESCO Finland
Registered nurse
1.7
10.8
263
1719
A01
ICPC
Pain general/multiple sites
2.7
10.7
74
286
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.6
10.7
79
320
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.5
10.7
550
4333
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.9
10.7
43
114
M77.0
ICD-10 Finland
Medial epicondylitis
6.1
10.6
28
47
N01
ICPC
Headache
2.1
10.6
129
662
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
4.1
10.6
40
100
W00
ICD-10 Finland
Fall on same level involving ice and snow
2.2
10.6
114
556
ZXE00
NOMESCO Finland
One hour or less
1.6
10.5
390
2841
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
10.5
418
3098
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
4.9
10.4
33
69
A02BC03
ATC
lansoprazole; oral
1.7
10.4
245
1582
M02AA10
ATC
ketoprofen; topical
2.0
10.4
136
722
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
10.3
335
2362
G54.0
ICD-10 Finland
Brachial plexus disorders
5.8
10.3
28
49
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
10.3
190
1137
SPAT1216
SPAT
Assessment of functional ability
2.1
10.3
123
628
M75.3
ICD-10 Finland
Calcific tendinitis of shoulder
9.7
10.3
20
21
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.3
10.2
96
441
S20.2
ICD-10 Finland
Contusion of thorax
3.1
10.2
55
184
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.3
10.0
96
442
J01MA02
ATC
ciprofloxacin; systemic
1.6
10.0
338
2404
R52.2
ICD-10 Finland
Other chronic pain
4.4
9.9
35
82
H01
ICPC
Ear pain/earache
2.1
9.9
122
629
SPAT1263
SPAT
Sampling
1.5
9.9
416
3113
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.5
9.9
77
322
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.3
9.9
93
427
S86.3
ICD-10 Finland
Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level
6.6
9.7
24
37
NFL30
NOMESCO Finland
Transposition of muscle of hip or thigh
7.5
9.7
22
30
R20.2
ICD-10 Finland
Paraesthesia of skin
2.6
9.7
72
292
M76.6
ICD-10 Finland
Achilles tendinitis
3.6
9.7
42
119
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.5
9.7
592
4804
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
9.7
306
2135
SPAT1312
SPAT
General health counselling
1.6
9.7
318
2243
WX320
NOMESCO Finland
Spinalanesthesy
1.7
9.6
197
1220
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.3
9.6
84
374
R01AD09
ATC
mometasone; nasal
1.5
9.6
458
3520
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.3
9.6
89
408
S80.0
ICD-10 Finland
Contusion of knee
2.7
9.5
67
262
F29
ICPC
Eye symptom/complaint other
2.3
9.5
88
400
N05CF01
ATC
zopiclone; oral
1.6
9.5
276
1883
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
3.4
9.5
44
132
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
9.5
193
1193
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
9.5
349
2527
H53.1
ICD-10 Finland
Subjective visual disturbances
2.7
9.4
64
248
G43.9
ICD-10 Finland
Migraine, unspecified
2.6
9.4
67
266
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.6
9.4
267
1810
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.9
9.4
131
712
M54.1
ICD-10 Finland
Radiculopathy
3.8
9.4
38
102
L05
ICPC
Flank/axilla symptom/complaint
2.8
9.3
58
211
N05AH04
ATC
quetiapine; oral
1.8
9.3
167
987
N06AA09
ATC
amitriptyline; systemic
2.4
9.3
79
345
J02AC01
ATC
fluconazole; systemic
1.5
9.3
383
2843
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.6
9.3
64
251
R07.3
ICD-10 Finland
Other chest pain
2.2
9.3
91
426
L29
ICPC
Musculoskeletal sympt/complt other
2.5
9.2
72
300
S29
ICPC
Skin symptom/complaint other
1.8
9.2
156
905
C08CA01
ATC
amlodipine; oral
1.6
9.2
272
1862
A46
ICD-10 Finland
Erysipelas
2.0
9.2
119
627
B01AC04
ATC
clopidogrel; oral
2.0
9.2
113
584
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
9.1
452
3493
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
2.8
9.1
57
209
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.5
9.1
71
295
A02BC01
ATC
omeprazole; systemic
1.6
9.0
238
1578
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.5
9.0
71
298
M54.8
ICD-10 Finland
Other dorsalgia
3.3
9.0
43
132
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.4
9.0
72
306
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.1
9.0
48
160
S63.5
ICD-10 Finland
Sprain and strain of wrist
3.3
9.0
44
138
K30
ICD-10 Finland
Functional dyspepsia
2.1
9.0
99
490
R05
ICD-10 Finland
Cough
1.7
9.0
179
1099
A04
ICPC
Weakness/tiredness general
1.9
8.9
129
710
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
8.9
94
456
NB2AT
NOMESCO Finland
Intra artrial injection of shoulder with ultrasound guidance
12.6
8.9
15
12
M54.3
ICD-10 Finland
Sciatica
2.8
8.8
53
192
SPAT1262
SPAT
Handing over of treatment supplies
1.8
8.8
154
905
J01CE02
ATC
phenoxymethylpenicillin; oral
1.5
8.8
740
6356
R29
ICPC
Respiratory symptom/complaint other
2.4
8.7
70
298
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.5
8.7
385
2894
A29
ICPC
General symptom/complaint other
2.1
8.7
101
509
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.7
8.7
59
228
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
3.7
8.7
36
99
E66.01
ICD-10 Finland
Obesity due to excess calories
2.3
8.7
82
376
S76.4
ICD-10 Finland
Injury of other and unspecified muscles and tendons at thigh level
7.7
8.7
19
25
N06AX11
ATC
mirtazapine; oral
1.6
8.6
290
2046
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.6
8.6
37
105
S70.0
ICD-10 Finland
Contusion of hip
4.0
8.6
33
85
M54
ICD-10 Finland
Dorsalgia
2.0
8.6
111
587
A11
ICPC
Chest pain NOS
2.5
8.6
68
287
R00.0
ICD-10 Finland
Tachycardia, unspecified
3.1
8.5
44
144
KMAK
NOMESCO Finland
NA
1.5
8.5
535
4322
S43.4
ICD-10 Finland
Sprain and strain of shoulder joint
3.5
8.4
38
112
R03BA05
ATC
fluticasone; inhalant
1.7
8.4
180
1127
SPAT1301
SPAT
No procedures
1.6
8.4
282
1989
WX290
NOMESCO Finland
Other blockade of nerve
1.5
8.3
465
3661
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
3.7
8.3
35
98
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
2.8
8.3
52
191
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.5
8.2
63
261
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.7
8.2
172
1066
R01AD08
ATC
fluticasone; nasal
1.6
8.2
273
1921
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.2
8.1
83
396
M48.0
ICD-10 Finland
Spinal stenosis
2.2
8.1
83
397
D10
ICPC
Vomiting
2.4
8.0
68
298
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.2
8.0
83
400
A02BA02
ATC
ranitidine; systemic
1.7
8.0
156
950
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.8
8.0
149
894
R00.2
ICD-10 Finland
Palpitations
2.3
7.9
70
313
R06.4
ICD-10 Finland
Hyperventilation
5.0
7.9
24
49
XF402
NOMESCO Finland
ECG with work load test
2.0
7.9
98
510
S40.0
ICD-10 Finland
Contusion of shoulder and upper arm
3.1
7.9
41
135
R11
ICD-10 Finland
Nausea and vomiting
2.3
7.9
72
326
C03CA01
ATC
furosemide; systemic
1.7
7.9
183
1171
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.6
7.9
212
1413
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
7.8
99
519
N04BC05
ATC
pramipexole; oral
2.5
7.8
61
257
S21
ICPC
Skin texture symptom/complaint
1.9
7.8
114
629
SPAT1252
SPAT
Overall medication plan or its review
2.5
7.8
57
231
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
4.9
7.8
24
50
J01FA09
ATC
clarithromycin; systemic
1.5
7.8
304
2215
SPAT1260
SPAT
Consultation of another employee
1.7
7.8
157
966
R03BA02
ATC
budesonide; inhalant
1.7
7.7
163
1016
J20
ICD-10 Finland
Acute bronchitis
2.1
7.7
86
429
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
45.3
7.7
9
*
J05AB01
ATC
aciclovir; systemic
1.6
7.7
196
1283
M75.2
ICD-10 Finland
Bicipital tendinitis
5.6
7.7
21
38
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
4.0
7.7
29
74
B01AA03
ATC
warfarin; systemic
1.8
7.7
135
796
M70.7
ICD-10 Finland
Other bursitis of hip
4.8
7.7
24
51
SPAT1254
SPAT
Administration of medicine
1.8
7.6
134
788
S15
ICPC
Foreign body in skin
2.4
7.6
62
266
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
7.6
183
1180
NBG10
NOMESCO Finland
Acromioplastia
11.9
7.6
13
11
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
7.6
676
5781
WX002
NOMESCO Finland
Sedation and analgesia
1.7
7.5
161
1004
XQ800
NOMESCO Finland
Prick test
2.1
7.5
80
391
SGB10
NOMESCO Finland
Fiiling of rooth of tooth with one root channel
1.9
7.5
112
623
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
7.5
159
989
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
3.7
7.5
31
86
R03BB04
ATC
tiotropium bromide; inhalant
2.1
7.4
77
372
C01CA24
ATC
epinephrine; parenteral
2.3
7.4
67
304
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
7.3
123
713
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
7.3
116
660
73398
ICD-8 Finland
Other diseases of muscle, tendon and fascia, Alii definiti
+∞
7.3
7
*
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.8
7.3
43
155
C10AA01
ATC
simvastatin; oral
1.5
7.3
304
2240
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.8
7.2
46
171
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.3
7.2
65
293
L11
ICPC
Wrist symptom/complaint
2.1
7.2
75
362
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
2.7
7.2
47
180
K10.3
ICD-10 Finland
Alveolitis of jaws
2.6
7.2
48
187
R03AC03
ATC
terbutaline; inhalant
1.8
7.2
132
789
Z01.2
ICD-10 Finland
Dental examination
1.4
7.2
413
3245
R06AE07
ATC
cetirizine; oral
1.4
7.1
421
3324
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.3
7.1
34
106
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.8
7.1
118
682
SPAT1310
SPAT
Counselling related to known health issue
1.5
7.1
295
2170
L50.9
ICD-10 Finland
Urticaria, unspecified
3.0
7.1
38
129
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
7.1
245
1734
SPAT1211
SPAT
Application of soft bandage
2.0
7.0
83
424
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
3.0
7.0
38
130
M65.4
ICD-10 Finland
Radial styloid tenosynovitis [de Quervain]
5.0
7.0
21
43
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
7.0
120
700
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
7.0
125
738
C10AA05
ATC
atorvastatin; oral
1.5
7.0
283
2074
L86
ICPC
Back syndrome with radiating pain
2.6
7.0
49
196
C09CA06
ATC
candesartan; oral
1.6
6.9
178
1167
K04.0
ICD-10 Finland
Pulpitis
1.9
6.9
98
536
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
6.9
178
1170
SPAT1212
SPAT
Extensive examination of musculoskeletal system
2.1
6.9
75
369
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
6.9
208
1424
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.5
6.9
243
1727
Z2221
NOMESCO Finland
Medical doctor
1.5
6.9
264
1911
L14
ICPC
Leg/thigh symptom/complaint
2.3
6.9
61
276
R01AD12
ATC
fluticasone furoate; nasal
1.5
6.9
293
2165
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
6.8
139
857
G47.3
ICD-10 Finland
Sleep apnoea
1.6
6.8
183
1216
A02BD02
ATC
lansoprazole, tetracycline and metronidazole; systemic
4.2
6.8
24
58
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.3
6.8
58
257
K08.80
ICD-10 Finland
Toothache NOS
2.0
6.8
79
402
-1
NOMESCO Finland
NA
1.4
6.8
347
2659
S04
ICPC
Lump/swelling localized
1.9
6.7
90
481
M22.4
ICD-10 Finland
Chondromalacia patellae
3.2
6.7
33
106
SGA01
NOMESCO Finland
Tooth opening as first aid
1.6
6.7
159
1024
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.2
6.6
66
313
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
3.0
6.6
36
124
M76.8
ICD-10 Finland
Other enthesopathies of lower limb, excluding foot
5.9
6.6
17
29
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
4.1
6.6
24
60
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
4.6
6.6
21
46
R07.0
ICD-10 Finland
Pain in throat
2.1
6.6
68
327
M70.5
ICD-10 Finland
Other bursitis of knee
12.3
6.6
11
9
S61.0
ICD-10 Finland
Open wound of finger(s) without damage to nail
1.9
6.6
93
508
XA402
NOMESCO Finland
ENMG
4.4
6.6
22
51
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.5
6.5
223
1567
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
6.5
139
865
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
6.5
384
3018
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.2
6.5
61
283
A07AA02
ATC
nystatin; oral
2.4
6.5
53
230
XF600
NOMESCO Finland
Bloodpressure measurement
2.3
6.5
60
274
R96
ICPC
Asthma
2.1
6.5
72
359
ZXD05
NOMESCO Finland
Urgent procedure
1.5
6.5
282
2090
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.1
6.4
70
347
N03AF01
ATC
carbamazepine; oral, rectal
2.6
6.4
45
178
J01MA12
ATC
levofloxacin; systemic
1.7
6.4
149
952
F43.00
ICD-10 Finland
Acute stress reaction mild
3.1
6.4
32
104
D19
ICPC
Teeth/gum symptom/complaint
1.5
6.4
252
1829
C01DA14
ATC
isosorbide mononitrate; oral
1.9
6.4
88
478
L60.0
ICD-10 Finland
Ingrowing nail
3.0
6.4
34
116
M01AB08
ATC
etodolac; oral
2.2
6.4
62
292
L84
ICPC
Back syndrome without radiat pain
2.7
6.4
41
155
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
2.5
6.3
48
199
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.8
6.3
97
546
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.3
6.3
54
239
B02.9
ICD-10 Finland
Zoster without complication
2.4
6.3
49
208
M70.4
ICD-10 Finland
Prepatellar bursitis
6.0
6.3
16
27
B35.4
ICD-10 Finland
Tinea corporis
6.0
6.3
16
27
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.0
6.3
81
427
K04.08
ICD-10 Finland
Other specified pulpit
2.0
6.3
71
358
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.0
6.2
73
373
J01MA14
ATC
moxifloxacin; systemic
2.0
6.2
73
373
D17.2
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
4.3
6.2
21
49
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
26.8
6.2
8
*
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.2
6.2
61
288
L16
ICPC
Ankle symptom/complaint
1.8
6.2
96
543
R5599
NOMESCO Finland
Other rehabilitation service
3.7
6.2
25
69
M75.8
ICD-10 Finland
Other shoulder lesions
3.4
6.2
28
85
F51.0
ICD-10 Finland
Nonorganic insomnia
1.7
6.2
126
775
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.5
6.1
44
179
R06AX27
ATC
desloratadine; oral
1.5
6.1
265
1959
S50.0
ICD-10 Finland
Contusion of elbow
3.0
6.1
33
114
H13
ICPC
Plugged feeling ear
1.6
6.1
141
899
NBL22
NOMESCO Finland
Myotomy, tenotomy or excision of tendon of upper arm
8.6
6.1
12
14
ZA6.0
ICD-10 Finland
Lower leg
6.7
6.0
14
21
K59.09
ICD-10 Finland
Constipation, unspecified
2.5
6.0
44
181
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
6.0
112
672
E66.8
ICD-10 Finland
Other obesity
2.3
6.0
52
232
L72.1
ICD-10 Finland
Trichilemmal cyst
2.2
6.0
55
253
Mortality – FinRegistry
↥Association
Association between endpoint M13_MUSCLESTRAIN and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_MUSCLESTRAIN | 1.129 [0.95, 1.34] | 0.17 |
| Birth year | 0.995 [0.99, 1.0] | 0.281 |
During the follow-up period (1.1.1998 — 31.12.2019), 321 out of 4277 females with M13_MUSCLESTRAIN died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_MUSCLESTRAIN | 1.068 [0.9, 1.27] | 0.465 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 365 out of 4901 males with M13_MUSCLESTRAIN died.
Mortality risk
Mortality risk for people of age
years, who have M13_MUSCLESTRAIN.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.136% | 0.164% |
| 5 | 0.711% | 1.296% |
| 10 | 1.856% | 2.923% |
| 15 | 3.398% | 5.774% |
| 20 | 6.021% | 9.868% |
Relationships between endpoints
↥Index endpoint: M13_MUSCLESTRAIN – Muscle strain
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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