Retinal breaks without detachment

H7_RETINALBREAK

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H33.3
  • Hospital discharge: ICD-9 3613
  • Cause of death: ICD-10 H33.3
  • Cause of death: ICD-9 3613

2 out of 7 registries used, show all original rules.

6354

4. Check minimum number of events

None

6354

5. Include endpoints

None

6354

6. Filter based on genotype QC (FinnGen only)

6354

Control definitions (FinnGen only)

Control exclude
H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H33
Name in latin
Ruptura retinae sine ablatione

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 37057 20151 16809
Only index persons 36278 19857 16421
Unadjusted period prevalence (%)
Whole population 0.53 0.58 0.47
Only index persons 0.68 0.73 0.63
Median age at first event (years)
Whole population 60.88 60.16 61.81
Only index persons 60.82 60.09 61.71

-FinnGen-

Key figures

All Female Male
Number of individuals 6354 3558 2796
Unadjusted period prevalence (%) 1.22 1.21 1.23
Median age at first event (years) 61.24 59.65 63.27

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
5622
Matched controls
56219
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H43.8
ICD-10 Finland
Other disorders of vitreous body
8.0
323.0
1566
2576
CKC10
NOMESCO Finland
Local photocoagulation of retina
402.3
323.0
711
20
WX140
NOMESCO Finland
Parabulbar anesthesy
17.6
323.0
624
396
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
498.0
323.0
330
7
CKC12
NOMESCO Finland
Photocoagulation of retina
1565.0
323.0
3336
51
H33.0
ICD-10 Finland
Retinal detachment with retinal break
2400.3
323.0
1048
5
H33.3
ICD-10 Finland
Retinal breaks without detachment
4503599627370496.0
323.0
5592
9
H43.1
ICD-10 Finland
Vitreous haemorrhage
35.5
323.0
604
190
CKD40
NOMESCO Finland
Endophotocoagulation of retina
300.6
307.8
311
11
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
61.2
289.1
340
59
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
90.5
283.8
316
37
H35.4
ICD-10 Finland
Peripheral retinal degeneration
518.5
251.8
249
5
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
225.8
231.6
238
11
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.5
227.6
899
2276
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
104.2
209.9
230
23
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
113.4
200.7
218
20
Z96.1
ICD-10 Finland
Presence of intraocular lens
3.8
196.7
930
2754
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.4
192.7
2217
11811
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
4.9
175.9
626
1402
CKC60
NOMESCO Finland
Local buckling of sclera using implant
1744.1
168.5
163
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.4
167.0
1810
9178
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
59.9
138.3
163
28
CKC30
NOMESCO Finland
Cryopexy of detached retina
1344.6
134.9
131
*
H26.4
ICD-10 Finland
After-cataract
3.7
134.0
645
1900
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.0
126.7
2521
16249
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
260.0
124.5
127
5
H33.5
ICD-10 Finland
Other retinal detachments
28.3
122.0
168
61
CJB10
NOMESCO Finland
Laser discission of secondary cataract
3.7
119.6
566
1636
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
90.1
118.6
132
15
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
77.7
113.8
129
17
CKD20
NOMESCO Finland
Removal of vitreous body substitute
527.6
105.0
104
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
254.6
98.0
100
*
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
13.7
97.4
172
129
H25.1
ICD-10 Finland
Senile nuclear cataract
2.1
95.1
1368
7539
S01ED51
ATC
timolol, combinations; ophthalmic
3.4
94.9
511
1626
H35.37
ICD-10 Finland
Macular holes
315.4
93.1
94
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
4.1
92.8
387
995
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
88.8
85
*
H34.8
ICD-10 Finland
Other retinal vascular occlusions
98.7
88.2
97
10
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
226.0
86.6
89
*
CKC15
NOMESCO Finland
Panretinal photocoagulation
223.4
85.6
88
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
84.1
961
4754
H52.1
ICD-10 Finland
Myopia
5.2
78.8
256
509
CKD15
NOMESCO Finland
Injection of vitreous substitute
382.5
75.9
76
*
XCH00
NOMESCO Finland
Eye pressure measurement
4.1
70.1
292
747
H53.1
ICD-10 Finland
Subjective visual disturbances
2.9
65.6
429
1552
CKC20
NOMESCO Finland
Cryopexy of undetached retina
225.9
65.3
67
*
H33
ICD-10 Finland
Retinal detachments and breaks
47.1
64.7
79
17
XCK10
NOMESCO Finland
Photography of fundus of eye
2.5
63.1
538
2274
ZXA05
NOMESCO Finland
Left side
1.7
60.6
1454
9365
ZXA00
NOMESCO Finland
Right side
1.7
56.4
1539
10255
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.1
53.9
640
3173
H43.9
ICD-10 Finland
Disorder of vitreous body, unspecified
10.0
52.5
107
109
H26.2
ICD-10 Finland
Complicated cataract
8.1
51.8
119
149
WX002
NOMESCO Finland
Sedation and analgesia
1.7
48.2
1115
7022
S01EA03
ATC
apraclonidine; ophthalmic
10.7
47.5
93
88
H25.8
ICD-10 Finland
Other senile cataract
2.1
45.1
545
2712
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.3
45.0
242
763
H43.3
ICD-10 Finland
Other vitreous opacities
5.9
42.7
122
209
H26.02
ICD-10 Finland
Presenil cataract
3.5
41.3
203
598
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
+∞
39.6
38
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
11.3
39.0
74
66
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.4
38.9
198
600
H35.7
ICD-10 Finland
Separation of retinal layers
201.3
38.9
40
*
S01BC05
ATC
ketorolac; ophthalmic
3.2
38.0
206
654
XCD20
NOMESCO Finland
Photoangiography of eye
14.9
37.0
62
42
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
+∞
36.5
35
*
H33.4
ICD-10 Finland
Traction detachment of retina
+∞
34.4
33
*
3613A
ICD-9 Finland
Retinal detachments and defects, Retinal defects without detachment
+∞
34.4
33
*
ZXA10
NOMESCO Finland
Bilateral
1.6
34.1
929
6060
H35.6
ICD-10 Finland
Retinal haemorrhage
65.4
34.0
39
6
S01ED01
ATC
timolol; ophthalmic
3.1
33.9
197
658
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
17.2
33.6
53
31
S01EE01
ATC
latanoprost; ophthalmic
2.4
33.2
308
1351
H35.36
ICD-10 Finland
Macular cyst
329.0
32.9
33
*
H33.2
ICD-10 Finland
Serous retinal detachment
117.4
32.7
35
*
S01EC01
ATC
acetazolamide; systemic
4.3
32.5
125
299
H3601, E113
ICD-10 Finland
NA
+∞
32.3
31
*
H3600, E113
ICD-10 Finland
NA
+∞
31.3
30
*
A98
ICPC
Health maint/preventive medicine
1.9
29.7
5322
50754
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.6
29.4
137
388
H20.1
ICD-10 Finland
Chronic iridocyclitis
6.6
29.1
76
117
H43
ICD-10 Finland
Disorders of vitreous body
7.6
27.9
66
88
H25.0
ICD-10 Finland
Senile incipient cataract
2.2
27.3
301
1432
H3603, E103
ICD-10 Finland
NA
+∞
27.1
26
*
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
75.5
26.8
30
*
WX142
NOMESCO Finland
Sub-tenon anesthesy
13.7
26.2
45
33
H3600, E103
ICD-10 Finland
NA
+∞
26.1
25
*
H3603, E113
ICD-10 Finland
NA
+∞
26.1
25
*
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
73.0
25.8
29
*
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
25.3
496
2926
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
3.3
25.0
131
408
114
Kela drug reimbursment
Glaucoma
1.9
24.1
401
2239
H40.0
ICD-10 Finland
Glaucoma suspect
1.9
23.8
379
2085
F05
ICPC
Visual disturbance other
2.9
23.7
150
533
H30.2
ICD-10 Finland
Posterior cyclitis
240.9
23.7
24
*
H35.9
ICD-10 Finland
Retinal disorder, unspecified
65.2
22.8
26
*
H35.8
ICD-10 Finland
Other specified retinal disorders
62.7
21.8
25
*
CKD50
NOMESCO Finland
Endodiathermy of retina
220.8
21.6
22
*
XCK00
NOMESCO Finland
Perimetry
1.9
21.6
309
1637
F29
ICPC
Eye symptom/complaint other
1.8
21.5
397
2296
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
11.9
21.4
39
33
S01EC04
ATC
brinzolamide; ophthalmic
2.4
20.1
180
777
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
19.9
876
6316
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
+∞
19.8
19
*
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
+∞
19.8
19
*
R01AD09
ATC
mometasone; nasal
1.3
19.7
2119
17746
S01BC03
ATC
diclofenac; ophthalmic
3.0
19.6
114
385
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
21.6
19.5
28
13
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.4
18.4
66
150
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
4.8
18.3
61
129
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
52.7
17.9
21
*
3745
FHL
Hard membrane girding, cerclage with coagulation
+∞
17.7
17
*
F04
ICPC
Visual floaters/spots
5.9
17.3
48
82
R01AD08
ATC
fluticasone; nasal
1.3
17.3
1320
10460
H3601, E103
ICD-10 Finland
NA
+∞
16.7
16
*
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
35.1
16.6
21
6
H53.8
ICD-10 Finland
Other visual disturbances
3.9
16.5
68
177
H34.1
ICD-10 Finland
Central retinal artery occlusion
170.4
16.5
17
*
H27.1
ICD-10 Finland
Dislocation of lens
9.5
16.4
33
35
H36.01
ICD-10 Finland
Diabetic maculopathy
47.6
16.0
19
*
H34.2
ICD-10 Finland
Other retinal artery occlusions
85.3
15.6
17
*
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
8.2
14.7
32
39
1LA05
NOMESCO Finland
NA
+∞
14.6
14
*
CKD25
NOMESCO Finland
External drainage of subretinal fluid
+∞
14.6
14
*
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
1.9
13.7
193
1021
H57.1
ICD-10 Finland
Ocular pain
2.2
13.6
141
655
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
5.9
13.6
37
63
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
34.1
13.5
17
5
J01FA10
ATC
azithromycin; systemic
1.2
13.2
2703
24087
CS494
NOMESCO Finland
Other visual field testing
2.4
13.2
108
450
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
13.0
1285
10497
H53
ICD-10 Finland
Visual disturbances
4.4
13.0
46
105
A02BC05
ATC
esomeprazole; systemic
1.2
12.7
2008
17360
S01EE05
ATC
tafluprost; ophthalmic
2.1
12.7
149
733
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
12.7
1486
12404
H31.3
ICD-10 Finland
Choroidal haemorrhage and rupture
+∞
12.5
12
*
3747
FHL
Combined ablation and vitreous surgery with coagulation
+∞
12.5
12
*
S01FA04
ATC
cyclopentolate; ophthalmic
3.5
12.5
58
169
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.1
12.4
142
692
A02BC02
ATC
pantoprazole; systemic
1.2
12.3
3273
29890
H44.2
ICD-10 Finland
Degenerative myopia
12.4
12.1
21
17
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
12.1
1136
9209
A10AA01
ATC
NA
3.3
12.0
60
185
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
12.0
947
7493
CKD30
NOMESCO Finland
Internal drainage of subretinal fluid
+∞
11.5
11
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
6.1
11.0
29
48
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
28.1
10.7
14
5
J01CA04
ATC
amoxicillin; systemic
1.2
10.7
3983
37360
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
2.6
10.6
75
290
J01AA02
ATC
doxycycline; systemic
1.2
10.6
4014
37695
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
10.4
2347
20925
CKC75
NOMESCO Finland
Removal of cerclage from sclera
+∞
10.4
10
*
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
2.5
10.3
80
325
R01AD01
ATC
beclometasone; nasal
1.3
10.3
674
5176
M01AE02
ATC
naproxen; oral, rectal
1.2
10.2
2681
24242
A10BA02
ATC
metformin; oral
0.8
10.2
873
10692
G47.3
ICD-10 Finland
Sleep apnoea
1.3
10.2
984
7989
H36.00
ICD-10 Finland
Diabetic background retinopathy
7.9
10.1
22
28
S01EC54
ATC
brinzolamide, combinations; ophthalmic
3.1
10.0
54
178
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
10.0
1021
8342
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
9.9
1034
8476
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
9.8
2111
18701
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.4
9.7
503
3715
R01AD12
ATC
fluticasone furoate; nasal
1.2
9.7
1233
10342
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
6.8
9.6
23
34
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.5
9.6
330
2254
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
6.3
9.5
24
38
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.4
9.5
75
311
H31.0
ICD-10 Finland
Chorioretinal scars
100.2
9.4
10
*
F82
ICPC
Detached retina
100.2
9.4
10
*
G04CA01
ATC
alfuzosin; oral
1.4
9.4
514
3835
3759
FHL
Other measure in this category
+∞
9.4
9
*
TCK00
NOMESCO Finland
Photosensitisation of choroid and retina
+∞
9.4
9
*
H3602, E103
ICD-10 Finland
NA
+∞
9.4
9
*
H30.0
ICD-10 Finland
Focal chorioretinal inflammation
+∞
9.4
9
*
WX110
NOMESCO Finland
Local anesthesy
1.2
9.3
3285
30414
WX408
NOMESCO Finland
General anesthesy, balanced
1.2
9.2
1229
10354
J01FA09
ATC
clarithromycin; systemic
1.2
9.0
1417
12144
J31.0
ICD-10 Finland
Chronic rhinitis
1.5
9.0
315
2159
J02AC01
ATC
fluconazole; systemic
1.2
9.0
1751
15337
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
3.4
8.8
40
117
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
2.4
8.8
70
291
DFF00
NOMESCO Finland
Pure tone audiometry
1.4
8.7
388
2791
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
8.7
2066
18421
A10AA02
ATC
NA
2.5
8.7
66
267
M01AH05
ATC
etoricoxib; oral
1.2
8.6
2896
26609
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
8.5
1883
16661
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
16.3
8.5
13
8
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
1.6
8.5
198
1233
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
2.7
8.4
54
199
Q14.10
ICD-10 Finland
Congenital retinoschis
90.2
8.4
9
*
R05
ICD-10 Finland
Cough
1.3
8.4
848
6913
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
+∞
8.3
8
*
CKD75
NOMESCO Finland
Retinotomy
+∞
8.3
8
*
H02AB07
ATC
prednisone; oral
1.3
8.2
611
4779
S01KA02
ATC
hypromellose; ophthalmic
2.1
8.2
88
424
Z01.2
ICD-10 Finland
Dental examination
1.2
8.2
1784
15759
J01MA02
ATC
ciprofloxacin; systemic
1.2
8.1
1783
15761
H04AA01
ATC
glucagon; nasal, parenteral
2.8
8.1
49
177
M01AX05
ATC
glucosamine; oral
1.2
8.0
958
7967
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.4
8.0
423
3141
D07AC13
ATC
mometasone; topical
1.2
7.9
1269
10883
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
13.0
7.9
13
10
S01EE03
ATC
bimatoprost; ophthalmic
2.0
7.8
90
444
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
1.8
7.8
121
666
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
6.9
7.8
18
26
L15
ICPC
Knee symptom/complaint
1.2
7.7
929
7720
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
1.7
7.7
151
897
ZX198
NOMESCO Finland
Other local administration
4.1
7.6
28
69
WX320
NOMESCO Finland
Spinalanesthesy
1.2
7.6
1004
8427
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
7.6
1971
17646
J01DB01
ATC
cefalexin; oral
1.2
7.6
4094
38928
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.2
7.6
1509
13202
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.3
7.5
463
3520
M79.1
ICD-10 Finland
Myalgia
1.3
7.5
500
3851
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
80.2
7.4
8
*
S83.2
ICD-10 Finland
Tear of meniscus, current
1.5
7.3
275
1915
37600
ICD-8 Finland
Detachment of retina, Primaria
+∞
7.3
7
*
H30.8
ICD-10 Finland
Other chorioretinal inflammations
+∞
7.3
7
*
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
+∞
7.3
7
*
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.2
7.2
1598
14100
H53.4
ICD-10 Finland
Visual field defects
2.0
7.2
83
411
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
30.0
7.1
9
*
R74
ICPC
Upper respiratory infection acute
1.2
7.0
1018
8627
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
0.3
7.0
13
451
K03.64
ICD-10 Finland
Dental calculus supragingival
1.2
7.0
1094
9342
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.3
7.0
494
3838
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
2.9
7.0
40
138
R06AX27
ATC
desloratadine; oral
1.2
6.9
1085
9265
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
2.9
6.9
38
130
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
5.1
6.9
20
39
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
2.0
6.9
83
419
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
6.9
1636
14508
A97
ICPC
No disease
1.3
6.9
584
4648
F20.9
ICD-10 Finland
Schizophrenia, unspecified
0.3
6.8
16
494
A06AC51
ATC
ispaghula, combinations; systemic
1.5
6.8
204
1357
F28
ICPC
Limited function/disability (F)
3.4
6.8
30
88
H26.9
ICD-10 Finland
Cataract, unspecified
2.3
6.8
60
265
CA1ME
NOMESCO Finland
Ultrasound oculometry
3.5
6.8
29
83
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.3
6.7
565
4496
M03BX02
ATC
tizanidine; oral
1.2
6.7
2992
27865
N05CF02
ATC
zolpidem; oral
1.2
6.7
746
6145
R5140
NOMESCO Finland
Monitoring the use of the aid
1.3
6.7
444
3418
M01AB05
ATC
diclofenac; systemic, rectal
1.2
6.7
3296
30930
R03BA05
ATC
fluticasone; inhalant
1.2
6.6
720
5916
D01AE16
ATC
amorolfine; topical
1.3
6.6
512
4031
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
4.3
6.5
22
51
C07AA05
ATC
propranolol; systemic
1.2
6.5
785
6520
CKD60
NOMESCO Finland
Anterior vitrectomy
3.1
6.5
32
102
J02AC02
ATC
itraconazole; systemic
1.2
6.5
793
6598
WX199
NOMESCO Finland
Other local analgesia
1.8
6.5
106
600
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
2.2
6.4
61
281
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.3
6.4
510
4028
F01
ICPC
Eye pain
1.8
6.4
105
593
G04CA02
ATC
tamsulosin; oral
1.2
6.4
953
8093
M02AA07
ATC
piroxicam; topical
1.2
6.4
1690
15104
Z94.0
ICD-10 Finland
Kidney transplant status
2.6
6.4
45
177
H40.8
ICD-10 Finland
Other glaucoma
4.9
6.3
19
39
F45.8
ICD-10 Finland
Other somatoform disorders
1.5
6.3
207
1408
H3602, E113
ICD-10 Finland
NA
+∞
6.2
6
*
3742
FHL
Cryocoagulation under general anesthesia
+∞
6.2
6
*
CKE40
NOMESCO Finland
Transpupillary photocoagulation of lesion of retina
+∞
6.2
6
*
H35.1
ICD-10 Finland
Retinopathy of prematurity
+∞
6.2
6
*
R06AE07
ATC
cetirizine; oral
1.2
6.2
1897
17133
J05AB01
ATC
aciclovir; systemic
1.2
6.2
869
7332
M79.6
ICD-10 Finland
Pain in limb
1.2
6.2
1579
14061
H21.0
ICD-10 Finland
Hyphaema
4.8
6.2
19
40
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.7
6.2
141
2111
H11.3
ICD-10 Finland
Conjunctival haemorrhage
1.6
6.2
156
1000
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
0.7
6.2
208
2905
S01EE04
ATC
travoprost; ophthalmic
1.9
6.1
83
441
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
3.0
6.1
31
102
R03BA02
ATC
budesonide; inhalant
1.2
6.1
704
5825
H52.2
ICD-10 Finland
Astigmatism
2.2
6.0
53
237
S18
ICPC
Laceration/cut
1.2
6.0
1953
17720

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
6194
59374
2.72
36.29
22.5
21.7
135.9
135.4
g/l
1.93
6112
58562
6193
59372
2.70
36.04
22.4
21.6
6.5
6.7
e9/l
5.55
6032
57637
6192
59362
2.69
35.96
22.4
21.6
91.3
91.4
fl
0.97
6109
58543
6192
59367
2.69
35.86
22.4
21.6
4.5
4.5
e12/l
1.91
6023
57645
6189
59341
2.65
35.53
22.4
21.6
244.3
249.3
e9/l
8.24
6044
57811
6190
59358
2.66
35.48
22.3
21.5
30.4
30.4
pg
0.32
6107
58536
4525
40464
1.41
32.13
4.3
4.1
11.3
12.6
mm/h
8.21
4147
37419
5830
54993
1.73
31.16
5.3
5.1
2.7
2.8
mmol/l
0.96
5309
50541
6034
57542
1.97
30.63
11.4
10.9
25.6
26.4
u/l
3.49
5785
55532
5728
53902
1.64
29.36
4.8
4.6
4.7
4.7
mmol/l
0.85
5224
49825
5695
53523
1.62
29.26
4.8
4.5
1.5
1.5
mmol/l
1.81
5168
49153
5319
49373
1.47
27.66
5.0
4.7
1.9
2.1
mu/l
1.79
4800
45051
6017
57521
1.87
27.41
17.7
17.3
78.4
77.3
umol/l
1.78
6012
57502
5527
51727
1.53
27.39
4.2
4.1
1.2
1.3
mmol/l
8.60
4979
47110
5664
53329
1.57
26.93
4.9
4.8
5.9
6.0
mmol/l
6.10
5106
48614
5169
47795
1.44
26.74
16.6
15.8
39.7
39.7
%
0.12
3768
33191
5689
53701
1.57
25.79
14.8
14.6
22.7
24.4
mg/l
3.13
4396
42712
5920
56484
1.70
24.98
17.3
16.9
4.0
4.0
mmol/l
4.33
5746
55124
2706
22872
1.32
24.54
2.2
2.1
—
—
—
0
0
5901
56339
1.66
23.75
17.1
16.8
139.9
139.8
mmol/l
2.21
5743
55075
2845
24491
1.29
21.48
6.4
6.1
0.7
0.7
%
1.75
2655
22775
2919
25238
1.29
21.20
6.3
6.1
3.0
2.9
%
1.56
2726
23451
5828
55662
1.57
21.13
13.9
13.8
—
—
—
0
0
2985
25939
1.28
20.62
6.4
6.2
27.7
27.8
%
0.07
2778
24063
2948
25585
1.28
20.53
6.2
5.9
57.2
57.2
%
0.11
2755
23842
2925
25367
1.28
20.47
6.5
6.4
8.8
8.7
%
1.41
2736
23679
2505
21350
1.29
19.93
2.9
2.7
137.6
144.6
ug/l
0.56
2281
19684
5388
50831
1.39
19.35
5.9
5.8
39.1
39.7
mmol/mol
6.36
4914
46898
4082
37065
1.28
19.10
4.5
4.3
—
—
—
0
0
2211
18658
1.28
18.68
6.3
5.9
—
—
—
0
0
4448
41008
1.28
17.46
4.1
4.0
14.8
14.8
pmol/l
0.45
3999
37247
2571
22285
1.26
16.89
2.3
2.2
81.8
78.5
nmol/l
6.61
2279
19995
1377
11037
1.32
16.86
3.4
3.1
0.7
0.8
ug/l
0.35
955
7653
4613
42890
1.28
15.95
7.8
7.8
77.5
78.5
u/l
0.69
4337
40451
3097
27673
1.23
14.66
6.2
5.9
1.9
1.9
e9/l
0.75
2693
24163
526
3692
1.46
14.38
2.1
2.2
12.8
12.6
nmol/l
0.28
472
3245
3035
27122
1.23
14.15
6.1
5.8
0.0
0.0
e9/l
1.08
2598
23238
3017
26985
1.22
13.81
6.1
5.8
0.6
0.6
e9/l
1.73
2580
23099
3123
28041
1.22
13.73
6.4
6.0
0.2
0.2
e9/l
0.06
2714
24425
1178
9587
1.28
12.38
1.4
1.5
2.5
2.5
g/l
0.14
681
5700
1928
16643
1.23
11.99
4.2
4.0
—
—
—
0
0
1138
9266
1.28
11.86
1.3
1.3
34.9
35.2
iu/ml
0.03
362
2885
1086
8793
1.28
11.84
3.3
3.0
2.2
2.4
e6/l
0.23
584
4721
2181
19109
1.22
11.61
5.6
5.1
3.1
3.2
ug/l
0.05
1949
17161
3753
34680
1.20
11.10
3.2
3.1
48.9
50.9
u/l
0.58
3447
32120
1721
14781
1.23
11.06
3.4
3.1
—
—
—
0
0
1080
8816
1.27
10.94
1.3
1.3
12.7
13.7
u/ml
0.18
370
3395
504
3692
1.40
10.86
2.4
2.4
25.4
23.8
au/ml
0.08
23
168
3439
31587
1.19
10.66
9.0
9.4
4.0
4.1
e9/l
2.48
2975
27463
2543
22745
1.20
10.59
2.0
2.0
98.3
95.3
pmol/l
2.12
1250
11753
1289
10851
1.24
9.87
1.3
1.2
2.3
1.9
u/ml
0.21
291
2863
3058
27919
1.18
9.79
7.0
6.7
1.2
1.2
mmol/l
5.68
2593
23613
2164
19186
1.19
9.69
4.1
3.7
60.8
102.2
e6/l
3.71
1490
13638
885
7150
1.28
9.68
1.4
1.3
624.0
525.9
titre
0.58
172
1521
456
3352
1.39
9.63
1.3
1.3
24.8
51.2
au/ml
4.10
15
150
1146
9549
1.24
9.61
3.0
2.8
1.4
1.4
e6/l
0.04
642
5439
967
7913
1.26
9.50
1.2
1.2
—
—
—
0
0
727
5752
1.30
9.35
4.3
4.2
—
—
—
0
0
1729
15070
1.20
9.25
1.7
1.6
1.3
1.4
mmol/l
9.11
1423
12558
1639
14216
1.21
9.23
4.0
4.0
90.2
89.9
%
0.18
1614
13893
317
2203
1.46
9.16
2.5
2.8
—
—
—
0
0
2110
18744
1.19
9.10
3.5
3.5
2.4
2.4
mmol/l
0.24
1800
16291
797
6404
1.28
9.08
1.3
1.3
—
—
—
0
0
1753
15319
1.20
9.08
3.5
3.2
0.3
0.4
e6/l
0.98
1275
11451
156
926
1.70
8.95
1.9
1.9
203.9
196.4
pmol/l
0.35
147
876
2789
25395
1.18
8.89
6.2
6.0
1.2
1.2
mmol/l
7.67
2480
23040
518
3949
1.34
8.69
1.2
1.2
—
—
—
0
0
1971
17460
1.19
8.68
2.5
2.4
—
—
—
0
0
903
7430
1.25
8.40
1.3
1.3
—
—
—
0
0
3793
35507
1.17
8.25
4.6
4.4
1518.0
1263.1
e6/l
0.12
34
483
1874
16592
1.18
8.21
3.6
3.3
52.7
77.5
e6/l
0.90
1391
12683
268
3810
0.69
8.02
5.1
5.0
—
—
—
0
0
280
1957
1.45
7.90
1.1
1.1
—
—
—
0
0
251
3588
0.69
7.75
7.2
7.2
24.8
24.7
mmol/l
0.17
223
3347
219
1470
1.51
7.58
1.2
1.3
94.4
34.5
u/ml
—
8
87
219
1473
1.50
7.51
1.0
1.1
—
—
—
0
0
4608
43990
1.17
7.22
18.8
17.9
13.6
13.7
%
5.20
4510
43074
2032
18300
1.16
6.95
3.0
3.0
—
—
—
0
0
2599
23842
1.15
6.90
10.2
9.7
0.0
0.0
e9/l
0.32
2092
19404
200
1351
1.50
6.76
1.2
1.3
1.9
2.8
u/ml
—
8
138
347
2590
1.36
6.73
1.2
1.2
—
—
—
0
0
201
1365
1.49
6.63
1.2
1.3
6.7
7.0
u/ml
0.03
25
225
1668
14874
1.16
6.39
2.6
2.7
4870.4
4486.6
umol/l
0.14
1424
12839
636
5199
1.25
6.23
2.5
2.4
42.9
48.6
u/l
0.23
548
4451
1885
17000
1.15
6.17
2.1
2.2
169.0
211.9
u/l
2.43
1764
15917
106
1729
0.61
6.16
4.9
4.3
3.9
3.9
mmol/l
0.27
96
1628
521
4167
1.27
6.15
4.1
3.6
85.9
89.5
ng/l
0.49
445
3585
1437
12709
1.17
6.08
1.6
1.5
21.7
20.6
nmol/l
1.83
1189
10857
71
377
1.89
6.04
1.1
1.1
—
—
—
0
0
1509
13410
1.16
5.99
2.5
2.3
—
—
—
0
0
131
2019
0.64
5.96
4.3
4.0
1.4
1.4
mmol/l
0.05
125
1989
1838
16591
1.15
5.89
4.5
4.1
7.4
7.4
ph
1.17
306
3148
999
8611
1.19
5.74
1.9
2.0
29.5
29.8
s
1.16
973
8374
78
435
1.80
5.71
2.4
2.4
—
—
—
0
0
41
181
2.27
5.69
2.1
1.5
—
—
—
0
0
347
2670
1.32
5.53
1.5
1.5
—
—
—
0
0
75
419
1.80
5.47
1.2
1.2
—
—
—
0
0
723
6074
1.21
5.47
2.0
2.2
122.6
141.4
ug/g
0.84
558
4743
157
1060
1.49
5.40
1.2
1.2
40.0
45.5
u/ml
0.13
14
113
1333
11820
1.16
5.38
1.7
1.7
1.1
1.3
mg/l
2.46
1000
9116
3105
29135
1.13
5.34
6.1
6.5
11.3
11.4
umol/l
0.26
2930
27749
131
855
1.54
5.29
1.3
1.2
256.7
285.0
u/ml
0.60
84
535
86
507
1.71
5.23
1.2
1.5
—
—
—
0
0
219
1584
1.40
5.23
1.7
1.8
—
—
—
0
0
1197
10553
1.17
5.20
2.9
2.8
552.1
550.2
mosm/kgh2o
0.10
989
8971
80
466
1.73
5.09
1.1
1.1
—
—
—
0
0
204
1466
1.40
5.07
1.6
1.4
11.0
19.7
iu/ml
—
7
38
4641
44729
1.14
4.97
19.2
18.9
332.3
332.2
g/l
0.62
4618
44439
1157
10208
1.16
4.96
3.0
3.2
2.4
2.5
mmol/l
3.05
1006
8932
770
6573
1.20
4.92
1.4
1.5
—
—
—
0
0
4101
39243
1.13
4.85
3.9
3.9
—
—
—
0
0
200
1447
1.39
4.80
2.2
1.9
11.1
11.5
mg/l
0.22
187
1329
45
222
2.03
4.80
3.1
2.7
—
—
—
0
0
161
2267
0.70
4.68
4.8
4.8
—
—
—
0
0
3404
32273
1.12
4.60
4.8
4.7
6.6
6.7
mmol/l
0.63
3200
30300
187
1355
1.39
4.48
3.8
2.8
1.6
1.5
mg/l
0.40
170
1249
750
6445
1.19
4.44
1.9
1.6
—
—
—
0
0
2793
26235
1.12
4.39
5.1
4.9
0.0
0.0
estimate
0.36
493
4808
396
3198
1.25
4.38
3.4
3.3
4.5
4.4
pmol/l
0.33
355
2827
2821
26517
1.11
4.37
3.7
3.7
0.0
0.0
estimate
0.41
480
4685
32
145
2.21
4.26
5.7
4.6
—
—
—
0
0
127
1828
0.69
4.21
12.9
9.8
—
—
—
0
0
13
36
3.62
4.20
2.9
4.8
—
—
—
0
0
388
3149
1.25
4.12
1.3
1.3
161.8
224.4
u/ml
1.62
360
2893
453
5455
0.82
4.11
8.8
8.1
120.1
121.5
g/l
0.77
432
5266
31
141
2.20
4.10
1.1
1.1
—
—
—
0
0
373
3020
1.25
4.05
2.6
2.4
—
—
—
0
0
2565
24054
1.11
4.05
4.7
4.9
35.8
35.4
g/l
3.52
2358
22374
81
506
1.61
4.04
1.5
1.4
0.3
0.3
nmol/l
0.32
60
358
285
2248
1.28
3.87
2.4
2.4
3.7
3.8
g/l
0.75
195
1614
1026
11488
0.87
3.86
4.1
4.1
1.0
1.0
kg/l
1.13
167
1697
31
145
2.14
3.85
1.0
1.0
—
—
—
0
0
2766
26098
1.11
3.81
3.7
3.6
0.0
0.0
estimate
0.50
480
4718
213
1623
1.32
3.75
1.1
1.1
—
—
—
0
0
2436
22854
1.11
3.73
9.3
9.1
1.2
1.3
inr
0.67
643
6425
450
3756
1.21
3.69
1.2
1.2
—
—
—
0
0
308
2474
1.26
3.62
3.6
3.6
—
—
—
0
0
153
1116
1.38
3.60
1.7
1.7
284.3
306.7
mu/l
0.51
144
1027
556
4747
1.19
3.58
2.3
2.3
380.7
371.5
nmol/l
0.56
522
4362
169
1257
1.35
3.53
1.3
1.2
—
—
—
0
0
2721
25726
1.10
3.50
3.9
4.0
—
—
—
0
0
264
2094
1.27
3.47
2.4
2.4
10.3
10.2
g/l
0.19
220
1761
270
2148
1.27
3.46
3.9
3.7
24.8
25.0
mmol/l
0.67
250
1962
1431
13092
1.12
3.46
2.3
2.2
2.8
3.0
mg/l
2.39
1195
11185
213
1647
1.30
3.41
1.3
1.3
34.6
36.2
iu/l
0.26
188
1414
1297
14206
0.89
3.40
4.4
4.1
0.0
0.0
estimate
2.17
480
4630
28
133
2.11
3.38
1.1
1.1
—
—
—
0
0
506
5917
0.84
3.37
8.1
7.7
96.0
95.7
%
0.61
475
5704
248
1961
1.28
3.35
1.8
1.9
22.2
21.6
s
0.64
219
1718
566
6551
0.85
3.34
7.7
7.3
0.7
1.1
mmol/l
1.90
455
5151
91
1322
0.68
3.26
7.5
7.3
105.0
105.2
mmol/l
0.16
77
1188
91
1321
0.68
3.25
7.5
7.3
11.4
11.2
mmol/l
0.19
77
1187
404
3389
1.21
3.18
3.6
3.5
7.4
7.4
ph
1.35
45
426
571
6577
0.86
3.17
7.7
7.3
5.1
5.1
kpa
0.46
533
6296
571
6576
0.86
3.17
7.6
7.3
13.2
12.3
kpa
2.74
534
6292
138
1015
1.37
3.13
1.4
1.3
11.7
11.5
u/l
0.05
112
815
61
381
1.61
3.13
2.1
1.6
2093.7
1928.2
ml
0.31
17
91
84
565
1.49
3.11
1.2
1.3
—
—
—
0
0
132
967
1.37
3.08
1.6
1.4
—
—
—
0
0
408
3442
1.20
3.04
3.6
3.4
5.1
5.2
kpa
1.80
372
3184
1732
16109
1.10
3.03
2.9
2.9
1111.4
1246.8
ng/l
0.91
1470
13910
118
852
1.39
3.01
1.7
1.3
161.4
117.8
u/ml
0.46
18
177
98
686
1.44
2.98
1.2
1.3
—
—
—
0
0
1509
13975
1.10
2.86
7.1
7.0
—
—
—
0
0
190
1487
1.29
2.84
1.2
1.2
—
—
—
0
0
1479
13689
1.10
2.83
3.5
3.3
—
—
—
0
0
73
491
1.49
2.75
1.1
1.1
1.5
2.7
u/ml
1.10
33
181
218
1746
1.26
2.72
2.4
2.2
37.9
37.8
g/l
0.14
184
1502
1254
11539
1.11
2.68
2.7
2.6
4.2
5.2
e6/l
3.28
1072
10088
574
5043
1.15
2.63
1.8
1.5
—
—
—
0
0
284
2352
1.22
2.61
1.7
1.5
29.0
14.6
u/ml
—
9
56
388
3310
1.18
2.59
1.5
1.4
—
—
—
0
0
609
5380
1.15
2.58
1.4
1.4
—
—
—
0
0
15
62
2.42
2.53
6.1
12.5
5.1
5.3
mmol/l
0.15
15
62
381
3255
1.18
2.51
1.2
1.2
146.1
143.7
iu/ml
0.04
133
1230
272
2254
1.22
2.50
1.7
1.5
—
—
—
0
0
40
239
1.68
2.50
27.0
26.5
101.4
111.3
ug/l
0.53
31
198
67
453
1.48
2.49
1.1
1.1
1.8
2.3
u/ml
0.28
27
171
164
1286
1.28
2.46
1.8
1.7
52.9
4.5
iu/l
0.49
64
445
368
3146
1.18
2.42
1.8
1.9
1.3
1.4
g/l
0.16
333
2861
1179
10874
1.10
2.40
3.8
3.7
252.9
505.3
ng/l
1.82
927
8657
18
83
2.17
2.40
1.1
1.1
—
—
—
0
0
476
4158
1.16
2.38
1.4
1.4
—
—
—
0
0
46
714
0.64
2.38
4.5
5.0
366.7
355.4
umol/l
0.25
34
619
199
1605
1.25
2.38
1.5
1.5
1.2
1.2
g/l
0.75
189
1513
460
4024
1.15
2.27
2.8
2.8
10.5
10.4
g/l
0.08
421
3686
192
1552
1.24
2.26
1.5
1.5
0.2
0.2
g/l
0.32
183
1462
35
208
1.69
2.26
1.1
1.1
—
—
—
0
0
85
618
1.38
2.18
1.2
1.2
—
—
—
0
0
54
361
1.50
2.16
2.2
2.6
717.3
627.1
e6/l
0.44
25
157
78
561
1.40
2.14
1.1
1.1
0.9
1.9
u/ml
0.71
26
126
124
959
1.30
2.12
1.5
1.5
—
—
—
0
0
98
733
1.34
2.11
1.1
1.1
0.9
1.6
u/ml
0.54
37
282
52
347
1.50
2.11
1.3
1.3
106.0
141.4
pmol/l
0.16
17
107
11
251
0.44
2.10
15.5
12.0
801.9
820.7
nmol/l
0.05
11
235
707
6399
1.12
2.07
2.9
2.7
7.0
8.4
umol/l
1.09
627
5600
1512
14202
1.08
2.05
1.3
1.3
—
—
—
0
0
19
96
1.98
2.05
1.0
1.2
—
—
—
0
0
624
5613
1.12
2.04
1.8
1.5
—
—
—
0
0
53
358
1.48
2.04
1.7
1.5
69.2
69.3
umol/l
—
5
22
407
4631
0.87
1.99
4.0
3.4
—
—
—
0
0
562
5033
1.13
1.98
1.5
1.5
—
—
—
0
0
93
703
1.33
1.90
1.1
1.1
12.5
15.8
au/ml
—
5
35
153
1234
1.25
1.90
2.2
2.1
130.4
128.4
g/l
0.40
96
868
7
22
3.18
1.88
1.3
1.9
—
—
—
0
0
843
7746
1.10
1.87
2.0
2.0
—
—
—
0
0
25
144
1.74
1.84
1.1
1.0
—
—
—
0
0
144
1158
1.25
1.84
1.3
1.4
32.8
36.8
e6/l
0.07
106
886
116
910
1.28
1.82
1.3
1.2
—
—
—
0
0
202
1686
1.20
1.81
2.8
3.3
—
—
—
0
0
1080
10056
1.09
1.80
1.8
1.7
1109.8
1163.0
nmol/l
1.11
779
7618
15
73
2.06
1.80
1.7
1.6
143.2
115.0
ug/l
—
10
60
2197
21018
1.07
1.79
3.8
3.6
35.1
71.0
ng/l
0.98
1548
14765
236
2001
1.19
1.79
1.6
1.6
—
—
—
0
0
521
4685
1.12
1.75
2.6
2.6
66.5
66.4
g/l
0.12
464
4269
6
18
3.34
1.74
3.7
1.7
2.9
1.5
mg/l
—
6
13
69
507
1.36
1.72
1.2
1.2
—
—
—
0
0
8
30
2.67
1.72
1.0
1.0
—
—
—
0
0
49
339
1.45
1.72
1.1
1.1
—
—
—
0
0
26
155
1.68
1.72
1.4
1.6
0.7
0.5
mmol/l
0.04
26
145
143
1160
1.24
1.71
1.3
1.4
560.3
1447.6
e6/l
1.50
108
940
5
13
3.85
1.71
1.2
1.2
854.0
452.7
nmol/l
—
5
13
73
542
1.35
1.71
1.7
1.3
16.5
22.9
iu/ml
—
6
22
1838
17508
1.07
1.69
2.7
2.6
63.2
58.5
u/l
1.12
1661
16153
123
985
1.25
1.66
3.3
2.9
—
—
—
0
0
532
4809
1.12
1.64
2.7
2.8
143.4
183.5
ng/l
2.18
481
4398
427
3814
1.13
1.62
2.5
3.0
4.1
4.0
e9/l
0.20
315
2936
66
488
1.36
1.61
1.1
1.1
—
—
—
0
0
56
403
1.39
1.60
1.8
2.0
3.3
1.8
u/field
0.64
15
159
439
3932
1.13
1.60
2.4
2.4
—
—
—
0
0
150
1801
0.83
1.50
5.7
6.4
1.3
1.3
mmol/l
0.27
131
1600
775
7176
1.09
1.49
6.8
5.5
1.0
1.0
mmol/l
0.01
713
6675
319
2815
1.14
1.49
1.2
1.2
—
—
—
0
0
77
591
1.31
1.48
3.9
3.5
61.4
57.2
%
0.77
52
379
13
65
2.00
1.48
1.7
1.2
48.9
143.8
ng/l
0.95
13
43
38
259
1.47
1.47
1.4
1.2
—
—
—
0
0
284
2489
1.15
1.47
5.9
3.9
24.3
24.3
mmol/l
0.13
262
2238
19
109
1.75
1.46
1.0
1.1
0.6
1.7
u/ml
—
8
48
130
1067
1.22
1.44
1.2
1.3
—
—
—
0
0
80
621
1.29
1.43
1.1
1.1
0.5
1.1
u/ml
1.13
33
259
65
491
1.33
1.41
5.6
5.2
79.3
95.5
u/ml
0.10
17
145
791
7353
1.09
1.40
26.0
23.8
1.5
1.3
inr
1.43
127
1076
258
2255
1.15
1.40
1.7
1.7
—
—
—
0
0
76
589
1.29
1.38
1.9
1.7
—
—
—
0
0
153
1285
1.20
1.36
1.4
1.3
—
—
—
0
0
50
365
1.37
1.36
6.6
6.3
—
—
—
0
0
47
340
1.39
1.35
1.1
1.1
267.5
285.3
mg/l
0.22
39
300
39
274
1.43
1.32
2.4
2.8
—
—
—
0
0
86
685
1.26
1.28
1.2
1.3
—
—
—
0
0
80
633
1.27
1.26
1.1
1.1
4.2
4.6
u/ml
0.08
34
292
474
4330
1.10
1.25
3.7
3.9
0.5
0.7
%
0.85
109
1011
48
355
1.35
1.23
1.2
1.2
42.4
41.0
mg/l
0.08
39
304
9
45
2.00
1.23
1.4
1.5
—
—
—
0
0
35
245
1.43
1.23
1.0
1.0
—
—
—
0
0
31
212
1.46
1.22
1.1
4.9
65.6
61.8
mg/l
0.14
20
156
10
49
2.04
1.22
1.1
1.7
—
—
—
0
0
171
1470
1.17
1.19
1.3
1.3
—
—
—
0
0
124
1037
1.20
1.19
1.5
1.5
—
—
—
0
0
6
26
2.31
1.18
1.7
1.2
—
—
—
0
0
280
2494
1.13
1.18
1.7
1.7
1.5
1.6
g/l
1.09
237
2132
19
299
0.63
1.18
1.4
1.4
—
—
—
0
0
72
569
1.27
1.17
3.1
3.4
—
—
—
0
0
236
2084
1.14
1.15
1.2
1.3
0.2
1.1
u/ml
3.27
13
213
674
6284
1.08
1.14
1.8
1.7
—
—
—
0
0
976
9227
1.07
1.13
3.0
3.3
0.8
0.8
mmol/l
1.37
902
8640
119
998
1.20
1.12
1.7
1.6
—
—
—
0
0
5
113
0.44
1.12
1.2
1.4
—
93.0
—
0
21
460
4224
1.10
1.12
3.9
4.1
0.1
0.3
%
0.39
124
1086
10
51
1.96
1.11
1.3
1.1
6.7
7.2
mmol/l
—
5
26
58
452
1.29
1.07
1.0
1.1
—
—
—
0
0
1839
17741
1.05
1.06
3.2
3.3
30.8
35.2
u/l
2.88
1744
16780
75
605
1.24
1.05
1.5
2.6
—
—
—
0
0
26
178
1.46
1.05
3.1
2.2
—
—
—
0
0
5
22
2.27
1.03
1.0
1.0
—
—
—
0
0
485
4484
1.09
1.03
4.0
4.2
0.1
0.2
%
2.54
138
1287
46
350
1.32
1.02
1.2
1.3
1.0
1.1
u/ml
0.05
28
169
10
53
1.89
1.01
2.8
2.2
—
—
—
0
0
32
230
1.39
1.01
1.2
1.1
77.2
409.2
ng/l
—
6
60
99
827
1.20
1.00
2.9
2.7
—
—
—
0
0
772
7282
1.07
0.98
2.9
2.5
25.1
22.7
%
3.79
667
6202
101
848
1.19
0.98
2.3
1.5
0.9
0.8
g/l
0.46
78
640
120
1023
1.18
0.98
2.6
3.7
64.1
30.4
u/ml
0.52
114
996
159
1386
1.15
0.97
4.0
4.1
—
—
—
0
0
1679
16196
1.05
0.97
3.1
3.1
—
—
—
0
0
40
301
1.33
0.96
1.6
1.7
12.0
9.7
umol/l
0.24
32
201
420
3876
1.09
0.95
1.5
1.4
—
—
—
0
0
79
650
1.22
0.95
2.6
2.3
—
—
—
0
0
308
2804
1.10
0.93
3.4
3.4
—
—
—
0
0
1120
11713
0.95
0.93
1.6
1.7
16338790.7
34657952.9
pmol/l
0.82
863
9767
8
142
0.56
0.93
2.0
2.3
—
—
—
0
0
152
1327
1.15
0.92
1.3
1.3
469.0
541.3
mg/l
2.25
147
1253
885
8405
1.06
0.92
2.8
2.4
13.8
13.0
umol/l
2.55
811
7793
63
509
1.24
0.90
2.3
2.3
—
—
—
0
0
27
193
1.40
0.90
1.0
1.1
1733.2
1607.5
miu/ml
0.23
27
193
12
71
1.69
0.88
1.5
1.8
2.8
2.9
mmol/l
0.09
12
62
23
160
1.44
0.88
3.5
2.2
0.5
1.0
ug/l
2.85
23
150
130
1130
1.15
0.86
4.9
2.9
—
—
—
0
0
12
72
1.67
0.85
1.7
1.7
—
—
—
0
0
17
112
1.52
0.84
4.6
4.4
32.7
48.3
u/l
—
6
37
151
1329
1.14
0.84
1.1
1.1
6.0
8.3
u/ml
0.24
19
140
14
215
0.65
0.84
1.6
2.2
633.0
4431.6
e6/l
—
7
147
64
524
1.22
0.83
2.2
2.4
1.3
1.1
e9/l
0.58
37
325
430
4001
1.08
0.82
3.8
3.0
4.7
4.6
kpa
0.26
418
3870
47
372
1.27
0.82
1.4
1.9
6.6
6.8
mmol/l
0.21
34
252
77
644
1.20
0.81
1.1
1.1
—
—
—
0
0
374
3463
1.08
0.81
1.3
1.3
—
—
—
0
0
42
329
1.28
0.80
1.2
1.0
—
—
—
0
0
74
618
1.20
0.80
4.4
4.1
—
—
—
0
0
675
6390
1.06
0.80
3.7
4.2
20.5
22.3
ug/l
0.07
527
5233
77
646
1.19
0.79
1.1
1.1
—
—
—
0
0
17
114
1.49
0.79
1.8
2.1
800.8
329.4
e6/l
0.36
12
53
1196
11507
1.05
0.78
4.4
4.7
—
—
—
0
0
210
2321
0.90
0.78
4.9
5.5
0.9
0.9
%
0.19
194
2178
72
602
1.20
0.77
1.4
1.6
—
—
—
0
0
0
27
0.00
0.77
0.0
1.0
—
—
—
0
0
279
2558
1.09
0.77
1.9
1.9
—
—
—
0
0
110
954
1.16
0.77
3.5
3.5
1.1
1.5
%
0.81
85
729
69
575
1.20
0.77
1.4
1.5
—
—
—
0
0
87
743
1.17
0.75
1.2
1.2
3.7
4.3
u/ml
0.19
38
304
161
1437
1.12
0.74
1.6
1.6
10742.5
14365.9
e6/l
0.49
104
1017
9
55
1.64
0.73
1.0
1.0
—
—
—
0
0
44
352
1.25
0.72
1.2
1.1
—
—
—
0
0
8
136
0.59
0.72
1.4
1.5
—
—
—
0
0
5
25
2.00
0.72
1.4
1.8
—
—
—
0
0
77
653
1.18
0.72
1.1
1.1
6.4
3.3
u/ml
0.41
39
274
45
362
1.24
0.71
1.2
1.3
—
—
—
0
0
140
1244
1.13
0.71
1.2
1.1
—
—
—
0
0
36
282
1.28
0.70
1.4
1.3
—
—
—
0
0
51
620
0.82
0.70
1.3
1.5
—
—
—
0
0
51
620
0.82
0.70
1.3
1.5
—
—
—
0
0
51
620
0.82
0.70
1.3
1.5
—
—
—
0
0
51
620
0.82
0.70
1.3
1.5
—
—
—
0
0
56
674
0.83
0.70
1.2
1.2
—
—
—
0
0
85
730
1.17
0.69
1.1
1.1
1.5
1.5
g/l
0.21
79
653
386
3607
1.07
0.69
2.7
2.9
—
—
—
0
0
175
1578
1.11
0.69
1.4
1.4
—
—
—
0
0
154
1379
1.12
0.69
2.6
2.9
24.8
24.9
mmol/l
0.07
132
1200
71
603
1.18
0.67
1.5
1.4
106127.9
57730.3
e6/l
0.55
38
350
5
28
1.79
0.66
4.2
3.4
—
—
—
0
0
89
1024
0.87
0.66
4.3
1.4
0.9
0.8
nmol/l
0.64
73
860
12
179
0.67
0.66
1.6
2.0
—
—
—
0
0
85
735
1.16
0.65
2.3
2.5
—
—
—
0
0
11
70
1.57
0.65
1.0
1.1
—
—
—
0
0
202
1845
1.10
0.64
3.5
3.0
0.3
0.3
g/l
0.11
86
754
812
7785
1.05
0.64
2.8
2.4
2.3
2.3
g/l
0.66
742
7199
85
737
1.16
0.63
5.8
6.5
10.8
11.8
mg/l
1.45
80
676
77
663
1.16
0.63
1.6
1.5
1788.3
2059.7
e6/l
0.27
53
475
216
2352
0.92
0.63
4.7
5.4
1.5
1.6
%
0.80
198
2202
145
1305
1.11
0.62
1.2
1.2
—
—
—
0
0
10
63
1.59
0.61
1.1
1.1
—
—
—
0
0
24
182
1.32
0.61
1.3
1.4
—
—
—
0
0
16
113
1.42
0.61
2.5
3.5
125.8
170.6
ng/l
—
5
39
200
1833
1.09
0.60
3.9
3.5
39.9
84.2
mg/l
0.81
165
1484
45
371
1.21
0.60
1.9
2.4
—
—
—
0
0
1797
17544
1.03
0.58
3.3
3.1
7.5
7.5
mmol/l
0.00
1507
14637
98
866
1.13
0.58
1.1
1.1
—
—
—
0
0
297
3177
0.93
0.57
10.3
9.8
—
—
—
0
0
5
89
0.56
0.56
1.6
1.6
—
—
—
0
0
5
89
0.56
0.56
1.6
1.2
0.2
2.1
mmol/l
—
5
63
64
550
1.17
0.55
1.8
1.3
3.0
2.9
g/l
0.21
46
385
64
550
1.17
0.55
1.8
1.3
0.3
0.4
g/l
0.90
44
384
199
1833
1.09
0.55
3.9
3.5
38.7
47.7
mg/l
0.51
165
1485
35
284
1.23
0.55
3.3
3.4
—
—
—
0
0
181
1661
1.09
0.55
1.5
1.4
271.4
273.9
ug/g
0.06
107
982
64
551
1.16
0.55
1.8
1.3
6.3
6.8
g/l
0.64
46
385
322
3024
1.07
0.54
9.2
9.3
24.3
24.4
mmol/l
0.07
301
2832
14
194
0.72
0.54
1.9
1.9
—
—
—
0
0
114
1022
1.12
0.54
1.5
1.5
—
—
—
0
0
11
159
0.69
0.54
1.9
1.4
—
—
—
0
0
20
151
1.33
0.53
1.1
1.1
—
—
—
0
0
20
151
1.33
0.53
1.1
1.1
—
—
—
0
0
20
151
1.33
0.53
1.1
1.1
—
—
—
0
0
67
581
1.15
0.53
1.6
1.2
—
—
—
0
0
18
134
1.34
0.53
1.2
1.4
—
—
—
0
0
26
205
1.27
0.52
1.2
1.1
—
—
—
0
0
37
305
1.21
0.51
1.0
1.1
—
—
—
0
0
9
64
1.41
0.51
1.1
1.2
—
—
—
0
0
9
64
1.41
0.51
1.1
1.2
—
—
—
0
0
9
64
1.41
0.51
1.1
1.2
—
—
—
0
0
1734
16958
1.03
0.51
3.4
3.1
428.3
418.0
mg/l
0.03
1057
10557
13
180
0.72
0.51
3.3
3.6
34.3
53.8
%
2.19
13
174
34
278
1.22
0.51
1.4
1.5
1.2
4.2
%
—
9
63
634
6086
1.05
0.50
2.4
2.5
1.7
1.8
%
0.76
540
5403
513
4900
1.05
0.50
4.9
3.7
1.9
2.0
mmol/l
0.17
418
3997
37
306
1.21
0.50
3.2
3.3
—
—
—
0
0
193
1789
1.08
0.48
3.9
3.5
2.5
2.1
ratio
—
10
143
7
108
0.65
0.48
1.1
1.4
—
—
—
0
0
7
46
1.52
0.48
1.1
1.2
—
—
—
0
0
16
119
1.35
0.48
1.1
1.1
—
588.6
—
0
7
34
281
1.21
0.47
1.1
1.1
—
—
—
0
0
18
137
1.31
0.47
1.9
1.3
155.1
62.3
mu/l
0.36
11
109
81
720
1.13
0.47
1.5
1.6
57.5
58.3
%
0.06
52
436
12
85
1.41
0.46
1.2
1.3
—
—
—
0
0
21
266
0.79
0.46
2.1
2.4
1773.3
1895.2
ml
0.16
16
234
25
310
0.81
0.46
1.4
1.3
—
—
—
0
0
80
897
0.89
0.45
1.6
1.4
—
—
—
0
0
261
2456
1.07
0.45
3.4
2.6
0.6
0.7
%
0.32
255
2345
67
591
1.14
0.44
1.1
1.1
—
—
—
0
0
495
4752
1.05
0.42
4.0
4.1
0.6
0.9
%
2.58
139
1395
75
838
0.89
0.41
1.3
1.3
0.4
0.3
nmol/l
—
5
57
85
766
1.11
0.41
2.0
1.4
68.6
61.4
mu/l
0.12
77
688
47
407
1.16
0.41
2.2
2.1
1.8
2.5
ug/l
1.35
40
340
14
105
1.33
0.41
1.6
1.5
91.4
124.1
ng/l
0.67
14
105
1818
17853
1.03
0.41
4.1
3.8
7.6
8.0
mg/mmol
0.14
1097
11085
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
480
4613
1.04
0.39
3.6
3.9
1.2
1.2
mmol/l
0.73
403
4088
511
4919
1.04
0.39
4.9
3.7
5.7
5.8
kpa
1.42
497
4776
45
517
0.87
0.39
4.2
2.8
51.8
43.5
mg/l
0.09
28
367
12
89
1.35
0.37
1.5
1.4
—
—
—
0
0
107
1165
0.92
0.37
2.8
2.8
32.4
34.7
umol/l
0.57
95
994
5
37
1.35
0.37
1.4
1.5
—
—
—
0
0
34
290
1.17
0.36
1.6
1.7
6.3
6.4
mmol/24h
—
7
19
34
290
1.17
0.36
1.0
1.1
7.1
11.3
iu/ml
—
9
79
457
4398
1.04
0.36
4.4
4.0
—
—
—
0
0
65
582
1.12
0.36
2.7
2.4
—
—
—
0
0
52
459
1.13
0.36
1.2
1.2
380.2
357.8
nmol/l
0.33
42
382
36
309
1.17
0.36
1.1
1.1
13.6
10.6
nmol/l
—
5
67
1296
12695
1.03
0.36
3.6
3.6
—
—
—
0
0
6
42
1.43
0.35
1.2
1.2
—
—
—
0
0
14
108
1.30
0.35
1.1
1.1
—
—
—
0
0
9
122
0.74
0.35
3.7
2.7
13067.4
2367.1
u/l
—
9
115
48
423
1.14
0.35
1.1
1.2
175.0
154.2
titre
—
6
78
20
163
1.23
0.34
1.4
1.2
412.3
301.7
ug/l
—
9
85
19
232
0.82
0.33
3.2
2.5
—
—
—
0
0
13
100
1.30
0.33
1.5
1.3
—
—
—
0
0
69
761
0.91
0.33
1.3
1.3
—
—
—
0
0
6
46
1.30
0.33
1.3
1.1
—
—
—
0
0
33
284
1.16
0.33
1.1
1.2
1.1
1.1
ratio
0.11
11
95
47
416
1.13
0.32
2.2
2.0
3.1
3.6
ug/l
0.36
42
366
202
1913
1.06
0.32
2.0
2.3
286.1
636.8
ug/l
1.80
194
1807
10
74
1.35
0.32
3.8
5.1
55.3
47.4
ug/min
—
10
57
302
2891
1.05
0.32
3.0
3.9
47.8
55.6
u/ml
0.21
288
2779
512
4956
1.04
0.32
8.4
6.8
9.6
9.7
mmol/l
0.13
485
4725
17
209
0.81
0.32
1.7
2.0
51.5
55.2
ug/l
0.13
17
203
474
4586
1.04
0.31
9.7
8.3
—
—
—
0
0
15
120
1.25
0.30
2.1
2.1
—
—
—
0
0
61
553
1.10
0.29
1.8
1.3
—
—
—
0
0
13
163
0.80
0.29
1.4
1.5
—
—
—
0
0
8
106
0.75
0.29
1.5
1.6
—
—
—
0
0
8
106
0.75
0.29
8.1
7.2
—
—
—
0
0
78
718
1.09
0.28
1.3
1.9
—
—
—
0
0
8
63
1.27
0.27
1.9
1.4
—
—
—
0
0
8
64
1.25
0.27
5.5
10.7
—
—
—
0
0
8
64
1.25
0.27
1.0
1.1
—
—
—
0
0
48
432
1.11
0.27
2.0
2.2
31.7
41.1
%
—
6
55
31
271
1.14
0.27
1.5
1.6
2.4
2.8
u/field
0.10
19
187
91
846
1.08
0.27
1.2
1.3
—
—
—
0
0
35
309
1.13
0.26
2.4
2.8
43.1
37.8
%
—
9
119
45
404
1.11
0.26
1.9
2.1
12.6
16.3
%
0.89
19
163
18
150
1.20
0.26
2.5
2.4
—
—
—
0
0
12
95
1.26
0.26
6.1
7.1
—
—
—
0
0
5
73
0.68
0.26
1.8
1.2
44.8
476.1
u/l
—
5
54
47
424
1.11
0.26
1.6
1.3
—
—
—
0
0
52
572
0.91
0.26
3.7
4.5
7.0
7.3
mmol/l
0.28
42
478
129
1217
1.06
0.25
1.7
1.7
—
—
—
0
0
10
127
0.79
0.25
1.2
1.1
—
—
—
0
0
35
393
0.89
0.25
1.3
1.3
12.7
11.6
mmol/l
0.28
14
110
297
2865
1.04
0.25
2.9
2.7
0.2
0.3
e6/l
2.43
284
2792
339
3279
1.04
0.24
3.9
3.2
128.5
129.2
g/l
0.24
333
3194
17
142
1.20
0.24
1.8
1.2
169.8
293.7
pmol/l
—
10
105
36
321
1.12
0.24
3.9
3.7
—
—
—
0
0
15
124
1.21
0.24
1.0
1.2
—
—
—
0
0
52
568
0.91
0.23
1.4
1.3
207467.9
89684.1
e6/l
0.48
38
384
12
147
0.82
0.23
1.2
1.1
—
—
—
0
0
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
116
1096
1.06
0.23
1.4
1.3
246.3
219.6
miu/ml
0.29
49
471
5
39
1.28
0.23
1.4
1.5
—
—
—
0
0
76
708
1.07
0.22
1.8
1.9
90.6
89.5
%
1.35
76
699
38
421
0.90
0.22
1.5
2.4
—
—
—
0
0
38
421
0.90
0.22
2.2
1.7
—
—
—
0
0
5
40
1.25
0.22
1.0
1.0
—
—
—
0
0
24
274
0.88
0.22
1.7
2.2
—
—
—
0
0
81
757
1.07
0.22
1.5
1.5
36.4
33.0
g/l
2.08
75
685
15
125
1.20
0.22
1.5
2.0
—
—
—
0
0
14
116
1.21
0.22
1.1
1.1
—
—
—
0
0
14
167
0.84
0.21
1.1
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
21
182
1.15
0.21
1.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
101
954
1.06
0.21
1.3
1.4
56.8
63.6
mmol/l
1.38
85
751
474
4627
1.03
0.21
2.4
2.5
70.0
69.8
e9/l
0.03
340
3488
8
105
0.76
0.21
3.6
2.7
14.4
14.9
ml/dl
—
8
99
6
49
1.22
0.20
1.0
1.1
—
—
—
0
0
125
1191
1.05
0.20
3.7
3.8
—
—
—
0
0
6
51
1.18
0.19
1.0
1.1
—
—
—
0
0
122
1163
1.05
0.19
2.6
2.8
8.2
8.0
kpa
0.62
105
1073
111
1165
0.95
0.18
2.9
3.4
26.4
27.3
mg/l
0.09
66
710
28
311
0.90
0.18
1.8
3.0
7.4
7.4
ph
0.08
11
110
58
541
1.07
0.18
1.4
1.5
28.4
31.5
%
0.26
36
325
10
121
0.83
0.18
1.4
1.6
—
—
—
0
0
134
1284
1.04
0.18
3.1
3.5
63.4
652.6
u/ml
2.16
119
1171
29
262
1.11
0.17
1.3
1.2
—
—
—
0
0
96
913
1.05
0.17
1.2
1.3
58.8
37.6
u/l
0.48
84
800
476
4857
0.98
0.17
2.3
2.3
7.2
7.4
ug/l
0.07
411
4265
7
63
1.11
0.17
1.0
1.2
—
—
—
0
0
250
2573
0.97
0.17
3.4
3.3
25.0
25.3
mmol/l
0.64
244
2493
95
905
1.05
0.16
1.5
1.4
—
—
—
0
0
73
690
1.06
0.16
1.5
1.6
—
—
—
0
0
27
296
0.91
0.14
2.9
1.8
—
—
—
0
0
122
1174
1.04
0.14
2.6
2.5
16.1
16.1
%
0.02
64
613
72
684
1.05
0.14
1.2
1.2
—
—
—
0
0
65
616
1.06
0.14
2.3
2.2
—
—
—
0
0
50
470
1.06
0.13
2.3
1.9
—
1.3
—
0
20
43
402
1.07
0.13
1.1
1.0
0.2
0.2
u/ml
—
10
104
32
296
1.08
0.13
1.7
2.1
512.0
495.4
min
0.55
22
236
138
1425
0.97
0.13
3.8
4.2
7.4
7.4
ph
2.12
124
1198
21
190
1.11
0.12
1.1
1.1
—
—
—
0
0
23
252
0.91
0.12
1.3
2.1
9.3
9.3
mmol/l
0.01
18
200
110
1061
1.04
0.12
3.2
3.0
0.8
0.8
nmol/l
0.54
86
805
529
5367
0.98
0.12
2.2
2.2
0.2
0.2
g/l
0.38
503
5008
19
210
0.90
0.12
1.3
2.1
58.7
146.6
umol/l
—
10
108
79
757
1.04
0.12
1.1
1.2
—
—
—
0
0
143
1388
1.03
0.12
3.9
3.7
—
—
—
0
0
494
4870
1.02
0.11
7.5
7.0
1.3
1.3
mmol/l
0.43
477
4701
70
731
0.96
0.11
1.3
1.3
—
—
nmol/l
—
0
0
45
425
1.06
0.11
1.2
1.2
—
—
—
0
0
125
1212
1.03
0.11
3.8
4.4
2.4
2.7
mmol/l
0.44
99
845
89
923
0.96
0.11
1.3
1.8
—
—
—
0
0
19
173
1.10
0.10
2.1
2.0
—
—
—
0
0
702
7094
0.99
0.10
7.3
7.1
104.6
104.5
mmol/l
0.09
689
6952
33
310
1.06
0.09
1.8
1.6
—
—
—
0
0
5
46
1.09
0.09
1.2
1.3
298.2
161.0
mmol/l
—
5
40
26
279
0.93
0.09
1.7
2.0
—
—
—
0
0
53
554
0.96
0.09
1.3
1.3
288.1
277.1
mosm/kgh2o
2.21
35
425
18
165
1.09
0.08
1.6
1.7
—
—
—
0
0
46
440
1.05
0.08
1.0
1.0
367.2
321.5
ng/l
0.57
35
303
28
264
1.06
0.07
5.8
10.3
—
—
—
0
0
46
441
1.04
0.07
1.0
1.0
698.2
720.7
ng/l
0.13
34
294
25
235
1.06
0.07
1.8
2.0
—
—
—
0
0
7
85
0.82
0.07
1.4
1.6
14.9
42.2
pmol/l
—
7
67
42
438
0.96
0.07
3.3
1.9
10.9
11.1
%
0.20
42
438
17
157
1.08
0.07
1.2
1.3
38.9
34.5
%
0.26
11
99
9
102
0.88
0.06
5.9
3.1
—
—
—
0
0
101
988
1.02
0.06
2.7
2.8
—
—
—
0
0
29
276
1.05
0.06
1.2
1.4
—
—
—
0
0
19
178
1.07
0.05
1.6
1.2
37.1
39.3
g/l
—
8
89
19
178
1.07
0.05
2.1
2.1
23.9
30.0
%
1.20
19
166
92
940
0.98
0.05
1.3
1.8
—
—
—
0
0
28
267
1.05
0.05
1.7
1.3
1.2
1.3
nmol/l
0.19
22
207
29
277
1.05
0.05
1.2
1.4
—
—
—
0
0
68
697
0.98
0.05
1.7
2.2
32.3
32.9
pg
0.52
68
692
17
159
1.07
0.05
1.1
1.1
—
—
—
0
0
34
353
0.96
0.04
1.1
1.1
—
—
—
0
0
15
140
1.07
0.04
1.7
1.3
13.1
24.7
%
1.97
15
119
587
5837
1.01
0.04
1.5
1.6
—
—
—
0
0
83
815
1.02
0.04
1.1
1.1
—
—
—
0
0
225
2229
1.01
0.04
3.2
3.6
456.4
1620.3
u/ml
1.26
191
1910
13
121
1.07
0.03
1.5
1.9
—
—
—
0
0
57
582
0.98
0.03
1.6
1.3
42.7
33.1
u/l
0.97
47
466
130
1314
0.99
0.03
2.3
2.2
—
—
—
0
0
18
172
1.05
0.02
1.6
1.3
4.1
3.4
mmol/l
0.52
18
151
233
2316
1.01
0.02
1.8
2.0
1.5
1.9
ug/l
0.31
192
2058
31
318
0.97
0.01
1.5
1.5
—
—
—
0
0
95
941
1.01
0.01
1.3
1.8
—
—
—
0
0
72
728
0.99
0.01
1.6
1.3
240.2
325.1
pmol/l
1.17
57
560
72
727
0.99
0.01
2.1
1.9
7992.2
2704.0
u/l
0.31
22
286
77
777
0.99
0.01
1.8
1.9
21.3
24.7
ug/l
0.39
77
765
94
947
0.99
0.01
1.3
1.8
—
—
—
0
0
17
176
0.97
0.00
1.1
1.2
—
—
—
0
0
19
184
1.03
0.00
1.3
1.1
—
—
—
0
0
42
426
0.99
0.00
2.0
2.2
792.8
643.8
ml
0.74
27
304
127
1264
1.00
0.00
2.2
2.2
189.1
99.7
ug/min
0.66
68
753
26
258
1.01
0.00
1.3
1.4
—
—
—
0
0
15
145
1.03
0.00
1.1
1.1
—
—
—
0
0
85
852
1.00
0.00
1.3
1.3
—
—
—
0
0
86
862
1.00
0.00
1.3
1.9
—
—
—
0
0
58
575
1.01
0.00
1.7
1.6
—
—
—
0
0
149
1488
1.00
0.00
1.3
1.2
1760.0
989.6
titre
—
5
50
29
286
1.01
0.00
1.3
1.5
—
—
—
0
0
52
516
1.01
0.00
1.6
1.5
—
—
—
0
0
77
774
0.99
0.00
1.1
1.1
56.7
14135.7
iu/ml
0.54
24
168
149
1486
1.00
0.00
1.3
1.2
329.0
188.1
titre
—
10
128
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
1596.2
—
0
8
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
0.00
1.6
2.1
21.8
17.6
umol/l
—
7
72
8
81
0.99
0.00
1.3
1.0
—
—
—
0
0
13
130
1.00
0.00
6.0
7.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
1496
14960
1.00
0.00
4.6
4.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
0.5
—
0
6
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
128.2
—
0
7

Mortality – FinRegistry

Association

Association between endpoint H7_RETINALBREAK and mortality.

Females

Parameter HR [95% CI] p-value
H7_RETINALBREAK 0.725 [0.65, 0.81] < 0.001
Birth year 0.996 [0.99, 1.0] 0.329

During the follow-up period (1.1.1998 — 31.12.2019), 1190 out of 17611 females with H7_RETINALBREAK died.

Males

Parameter HR [95% CI] p-value
H7_RETINALBREAK 0.638 [0.57, 0.71] < 0.001
Birth year 0.988 [0.98, 1.0] 0.008

During the follow-up period (1.1.1998 — 31.12.2019), 1476 out of 14412 males with H7_RETINALBREAK died.

Mortality risk

Mortality risk for people of age

years, who have H7_RETINALBREAK.

N-year risk Females Males
1 0.062% 0.134%
5 0.415% 0.759%
10 1.058% 1.968%
15 2.039% 3.615%
20 3.557% 6.424%

Relationships between endpoints

Index endpoint: H7_RETINALBREAK – Retinal breaks without detachment

GWS hits: 4

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data