Myeloproliferative diseases (CML excluded)

MYELOPROF_NONCML

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

  • not CML
519636

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D75.2

1 out of 7 registries used, show all original rules.

937

4. Check minimum number of events

None

937

5. Include endpoints

3004

6. Filter based on genotype QC (FinnGen only)

2932

Control definitions (FinnGen only)

Control conditions
not CML

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 2932 1559 1373
Unadjusted period prevalence (%) 0.59 0.55 0.63
Median age at first event (years) 63.96 62.50 65.62

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3004
Matched controls
30040
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D45
ICD-10 Finland
Polycythaemia vera
2178.5
307.7
1263
10
9950/3-C42.1
ICD-O-3
Polycythemia vera of bone marrow
+∞
307.7
412
*
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
5432.5
307.7
472
*
XW000
NOMESCO Finland
Bone marrow biopsy
23.5
307.7
958
588
L01XX05
ATC
hydroxycarbamide; oral
7124.2
307.7
1760
7
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
97.1
307.7
1930
546
SPAT1074
SPAT
Venesection
183.8
307.7
313
19
L03AB05
ATC
interferon alfa-2b; parenteral
119.2
307.7
221
20
D75.2
ICD-10 Finland
Essential thrombocytosis
4970.9
307.7
1042
*
B99
ICPC
Blood/lymph/spleen disease other
76.1
307.7
179
25
9962/3-C42.1
ICD-O-3
Essential thrombocythemia of bone marrow
+∞
307.7
458
*
TPH00
NOMESCO Finland
Phlebotomy
316.9
307.7
434
16
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
42.0
307.7
360
97
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
79.4
307.7
248
34
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
+∞
307.7
1389
*
L01XX35
ATC
anagrelide; oral
+∞
266.7
252
*
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
2082.5
214.0
205
*
D75.1
ICD-10 Finland
Secondary polycythaemia
23.8
177.8
128
56
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
161.0
697
2415
9960/3-C42.1
ICD-O-3
Myeloproliferative neoplasm, NOS, of bone marrow
1524.2
148.2
143
*
174
Kela drug reimbursment
Ruxolitinib
+∞
137.6
131
*
L03AB04
ATC
interferon alfa-2a; parenteral
235.5
132.0
135
6
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
22.5
130.6
96
44
M04AA01
ATC
allopurinol; systemic
3.0
126.7
703
2784
374
Kela drug reimbursment
Ruxolitinib
+∞
125.9
120
*
L01EJ01
ATC
ruxolitinib; oral
+∞
113.2
108
*
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
15.2
109.5
97
66
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
15.9
108.8
94
61
B74
ICPC
Malignant neoplasm blood other
39.1
106.0
65
17
212
Kela drug reimbursment
Gout
6.7
105.7
172
269
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
27.9
104.8
71
26
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.3
104.2
452
1539
B28
ICPC
Limited function/disability (B)
20.5
99.6
76
38
TPH00, ,
SPAT
189.7
88.8
92
5
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
7.7
77.8
110
147
L01XE18
ATC
[U] ruxolitinib
+∞
74.3
71
*
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
18.7
71.8
57
31
L03AA04, ,
ATC
26.9
65.5
45
17
WW500
NOMESCO Finland
Blood transfusion
3.7
62.1
209
599
B04
ICPC
Blood symptom/complaint
11.7
62.1
64
56
B03XA02
ATC
darbepoetin alfa; parenteral
4.5
54.0
133
303
D75.0
ICD-10 Finland
Familial erythrocytosis
76.6
53.2
60
8
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
19.7
50.3
39
20
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
8.3
49.2
65
80
XX7BT
NOMESCO Finland
Radioactive phosphorus therapy
+∞
48.0
46
*
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
19.2
45.8
36
19
B01AB05
ATC
enoxaparin; parenteral
1.7
39.5
1040
7105
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
9.3
39.2
47
51
D75.8
ICD-10 Finland
Other specified diseases of blood and blood-forming organs
51.9
38.6
46
9
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
36.0
1490
11350
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.4
33.2
235
1013
L01AB01
ATC
busulfan; systemic
+∞
31.3
30
*
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
10.1
30.9
35
35
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
30.2
933
6545
B03XA01
ATC
erythropoietin; parenteral
5.7
30.1
56
100
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
8.4
30.0
39
47
I81
ICD-10 Finland
Portal vein thrombosis
8.9
29.8
37
42
2384A
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Polycythaemia vera
+∞
28.2
27
*
B01AC14
ATC
[U] anagrelide
+∞
27.1
26
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.3
25.3
210
969
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
3.7
25.1
80
221
R50.9
ICD-10 Finland
Fever, unspecified
1.7
23.4
444
2722
B75
ICPC
Neoplasm blood benign/unspecified
231.7
22.6
23
*
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
18.1
22.2
34
19
D47.0
ICD-10 Finland
Histiocytic and mast cell tumours of uncertain and unknown behaviour
52.4
22.1
26
5
R04.0
ICD-10 Finland
Epistaxis
2.0
21.8
264
1406
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.5
21.6
143
597
S97
ICPC
Chronic ulcer skin
2.1
21.5
220
1102
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.0
21.3
250
1316
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
20.8
357
2123
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
20.3
653
4552
XW000, ,
SPAT
48.3
20.2
24
5
D73.5
ICD-10 Finland
Infarction of spleen
23.5
19.9
28
12
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
5.5
19.8
38
70
20899
ICD-8 Finland
Polycythaemia vera
+∞
18.8
18
*
B01AA03
ATC
warfarin; systemic
1.5
18.5
640
4525
306
Kela drug reimbursment
Erythropoietin and darbepoetin
7.5
18.2
26
35
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
18.0
361
2238
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.8
18.0
301
1774
C03CA01
ATC
furosemide; systemic
1.4
17.8
999
7754
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.8
17.4
296
1752
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
2.6
16.8
96
374
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.9
16.8
216
1173
PH_2
NOMESCO Finland
Other procedures on veins
+∞
16.7
16
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
16.2
700
5157
2387X
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Other lymphatic and haematopoietic tissues[STATUS LYMPHO- ET MYELOPROLIFERATIVUS NUD]
+∞
15.6
15
*
SPAT1088
SPAT
Blood transfusion
5.3
15.6
31
59
D75
ICD-10 Finland
Other diseases of blood and blood-forming organs
160.8
15.5
16
*
A05AA02
ATC
ursodeoxycholic acid; oral
3.5
15.2
52
151
Z3231
NOMESCO Finland
Registered nurse
1.4
14.9
762
5782
D69.1
ICD-10 Finland
Qualitative platelet defects
22.4
14.2
20
9
K99
ICPC
Cardiovascular disease other
2.4
14.2
98
419
D46.2
ICD-10 Finland
Refractory anaemia with excess of blasts [RAEB]
42.7
14.1
17
*
I50.9
ICD-10 Finland
Heart failure, unspecified
1.5
14.0
463
3226
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.9
13.6
162
858
J01DB01
ATC
cefalexin; oral
1.4
13.5
2293
20932
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
4.1
12.8
34
83
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
15.5
12.6
20
13
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
12.5
359
2420
2387B
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Other lymphatic and haematopoietic tissues[THROMBOCYTHAEMIA IDIOPATHICA]
+∞
12.5
12
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.6
12.3
327
2167
127
Kela drug reimbursment
Transplant complication
3.3
12.2
46
143
D47.7
ICD-10 Finland
Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
21.4
12.0
17
8
D68.8
ICD-10 Finland
Other specified coagulation defects
3.7
11.8
37
102
C94.5
ICD-10 Finland
Acute myelofibrosis
+∞
11.5
11
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
1.8
11.4
167
946
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
11.3
274
1777
Z2221
NOMESCO Finland
Medical doctor
1.4
11.2
705
5501
D73.1
ICD-10 Finland
Hypersplenism
20.1
11.1
16
8
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.7
11.1
224
1387
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
11.1
482
3533
C90.0
ICD-10 Finland
Multiple myeloma
3.1
11.0
46
152
D64.9
ICD-10 Finland
Anaemia, unspecified
1.5
11.0
321
2170
L57.0
ICD-10 Finland
Actinic keratosis
1.5
11.0
325
2204
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
2.4
10.9
71
296
D47
ICD-10 Finland
Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
43.5
10.9
13
*
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
3.1
10.9
45
148
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
10.8
592
4517
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
2.3
10.7
79
349
D46.0
ICD-10 Finland
Refractory anaemia without ring sideroblasts, so stated
21.5
10.7
15
7
M10.9
ICD-10 Finland
Gout, unspecified
1.7
10.7
208
1277
ZX120
NOMESCO Finland
Intravenous
1.6
10.6
259
1683
2387A
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Other lymphatic and haematopoietic tissues[MYELOFIBROSIS]
+∞
10.4
10
*
T14.5
ICD-10 Finland
Injury of blood vessel(s) of unspecified body region
4.1
10.4
28
69
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.4
10.3
529
3986
H02AB06
ATC
prednisolone; systemic
1.3
10.3
1295
11114
J01MA12
ATC
levofloxacin; systemic
1.4
10.3
513
3846
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
2.6
10.3
60
238
K29
ICPC
Cardiovascular sympt/complt other
1.9
10.3
133
725
R71
ICD-10 Finland
Abnormality of red blood cells
8.8
10.3
21
24
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
2.1
10.2
98
482
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.4
10.2
70
300
NHQ40
NOMESCO Finland
Amputation of toe
2.7
10.1
52
194
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
1.8
10.0
143
803
V03AC03
ATC
deferasirox; oral
40.2
10.0
12
*
B86
ICPC
OTHER HAEMATOLOGICAL ABNORMALITY
40.2
10.0
12
*
A46
ICD-10 Finland
Erysipelas
1.4
9.9
409
2963
WW200
NOMESCO Finland
Immunization
2.3
9.9
72
316
XQ848
NOMESCO Finland
Dermatological photography
2.1
9.8
86
408
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
20.1
9.8
14
7
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
2.8
9.6
47
170
A02BC02
ATC
pantoprazole; systemic
1.3
9.6
1902
17217
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
9.6
686
5443
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
1.9
9.6
109
570
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
2.7
9.5
51
194
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.6
9.5
235
1531
L04AD01
ATC
ciclosporin; systemic
2.7
9.4
50
189
B01AB04
ATC
dalteparin; parenteral
1.8
9.4
143
820
C03DA01
ATC
spironolactone; oral
1.5
9.4
351
2497
ZY010
NOMESCO Finland
Hospital outpatient
1.9
8.9
106
564
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
8.8
380
2773
C07AB07
ATC
bisoprolol; oral
1.3
8.7
1440
12686
PD4AD
NOMESCO Finland
CT of lower extremity arteries
3.7
8.7
27
74
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
1.6
8.7
185
1163
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
8.7
413
3069
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
27.6
8.5
11
*
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
1.8
8.5
120
674
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
2.4
8.4
57
243
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
8.4
716
5811
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
8.3
855
7103
R51.80
ICD-10 Finland
Headache
1.4
8.3
346
2512
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.3
8.2
519
4031
AA1AD
NOMESCO Finland
CT of head and brain
1.3
8.1
771
6339
K93
ICPC
Pulmonary embolism
3.0
8.1
35
119
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.4
8.1
315
2258
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.6
8.0
188
1210
B02BX05
ATC
eltrombopag; oral
10.0
8.0
15
15
D69.9
ICD-10 Finland
Haemorrhagic condition, unspecified
4.4
7.9
19
43
S91.0
ICD-10 Finland
Open wound of ankle
3.0
7.9
33
110
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
6.6
7.9
19
29
I67.6
ICD-10 Finland
Nonpyogenic thrombosis of intracranial venous system
7.8
7.9
17
22
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.5
7.8
256
1772
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.5
7.8
225
1518
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.7
7.8
326
4403
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.3
7.7
520
4077
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
7.7
894
7529
D58.2
ICD-10 Finland
Other haemoglobinopathies
25.1
7.6
10
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
7.5
1045
8980
M79.6
ICD-10 Finland
Pain in limb
1.2
7.4
1051
9053
ZYC01
NOMESCO Finland
Remote contact by phone
1.7
7.3
136
827
L71.9
ICD-10 Finland
Rosacea, unspecified
2.1
7.3
64
305
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
2.7
7.3
36
132
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
2.4
7.3
47
197
L17
ICPC
Foot/toe symptom/complaint
1.3
7.2
727
6009
I82.0
ICD-10 Finland
Budd-Chiari syndrome
15.8
7.2
11
7
B59
ICPC
Blood and Immunity, Other therap proced/minor surg NEC
30.1
7.1
9
*
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
7.1
450
3491
JMA11
NOMESCO Finland
Laparoscopic total splenectomy
8.8
7.0
14
16
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.3
7.0
446
3464
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
1.8
7.0
95
528
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
7.0
7.0
16
23
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
3.2
7.0
27
86
J01FF01
ATC
clindamycin; systemic
1.3
6.9
675
5553
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
1.8
6.9
91
502
N02AX02
ATC
tramadol; systemic, rectal
1.2
6.8
1148
10044
L29.8
ICD-10 Finland
Other pruritus
2.6
6.8
37
143
9989/3-C42.1
ICD-O-3
Myelodysplastic syndrome, NOS, of bone marrow
9.3
6.8
13
14
-69
ICPC
Other reason for encounter NEC
1.8
6.8
101
578
JN3AD
NOMESCO Finland
Abdominal CT examination
1.4
6.7
286
2082
UJF32
NOMESCO Finland
Coloscopy
1.3
6.7
703
5835
R89.8
ICD-10 Finland
Abnormal findings in specimens from other organs, systems and tissues, other abnormal findings
22.6
6.7
9
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.4
6.6
270
1954
WX892
NOMESCO Finland
Monitored bed care
1.5
6.6
197
1342
ZXE00
NOMESCO Finland
One hour or less
1.2
6.5
976
8426
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
6.2
6.5
16
26
DKW00
NOMESCO Finland
Cauterisation of mucosa of nose
2.7
6.4
32
118
K49
ICPC
Cardiovascular, Other preventive procedure
70.0
6.4
7
*
L03AB01
ATC
interferon alfa natural; parenteral
70.0
6.4
7
*
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.4
6.4
322
2411
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
7.4
6.4
14
19
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.4
6.4
251
1802
B01AB10
ATC
tinzaparin; parenteral
1.4
6.3
252
1813
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.2
6.3
24
76
28999
ICD-8 Finland
Other disease of blood and blood-forming organs, Other and unspecified
+∞
6.3
6
*
N02BE01
ATC
paracetamol; systemic, rectal
1.3
6.2
2507
23916
D06BB10
ATC
imiquimod; topical
1.6
6.2
126
786
R06.0
ICD-10 Finland
Dyspnoea
1.3
6.1
718
6030
R60.0
ICD-10 Finland
Localized oedema
1.4
6.1
322
2431
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
12.5
6.1
10
8
B01AC04
ATC
clopidogrel; oral
1.3
6.1
462
3678
I73.8
ICD-10 Finland
Other specified peripheral vascular diseases
8.6
6.0
12
14
M10.4
ICD-10 Finland
Other secondary gout
6.7
6.0
14
21
L04AX02
ATC
thalidomide; oral
10.0
6.0
11
11
I50.0
ICD-10 Finland
Congestive heart failure
1.4
6.0
215
1517

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
785
1909
5.21
310.85
9.8
3.7
0.98
0.62
%
4.43
408
638
2419
12251
6.00
307.65
14.5
5.5
0.07
0.04
e9/l
76.76
2228
10502
2446
12665
6.01
307.65
15.9
5.7
0.23
0.19
e9/l
5.96
2270
11003
2337
11170
5.92
307.65
16.0
5.8
1.06
0.66
%
84.69
2264
10358
2428
12519
5.90
307.65
14.8
5.6
1.97
1.91
e9/l
0.30
2280
10973
861
385
30.95
307.65
1.3
1.2
25.57
46.63
u/l
1.36
711
335
724
427
22.02
307.65
1.4
1.5
—
—
—
0
0
2372
11784
5.81
307.65
16.7
5.9
24.47
27.06
%
24.74
2304
10985
2417
12218
6.01
307.65
14.5
5.5
0.64
0.60
e9/l
1.90
2227
10478
2362
11495
5.94
307.65
16.2
5.7
2.68
2.85
%
3.90
2295
10676
661
263
31.94
307.65
1.3
1.2
—
—
—
0
0
500
221
26.94
307.65
1.1
1.2
—
—
—
0
0
849
2092
5.26
307.65
10.0
3.8
1.41
0.85
%
5.51
456
744
2449
11475
7.14
307.65
18.1
6.0
—
—
—
0
0
2363
11547
5.90
307.65
17.3
6.1
8.18
8.80
%
15.43
2295
10740
1733
6677
4.77
307.65
4.5
2.7
1610.18
5948.25
umol/l
7.53
1616
5751
1112
2308
7.06
307.65
3.8
2.5
79.16
68.76
e9/l
14.05
830
1773
2343
11601
5.63
307.65
15.2
5.7
61.28
57.71
%
37.08
2268
10800
1319
3112
6.77
307.65
3.9
2.5
1.88
1.79
%
2.48
1175
2733
787
1996
4.99
295.09
9.8
3.9
0.20
0.10
%
2.92
397
650
1090
3554
4.24
294.81
2.7
2.6
22.56
22.24
%
0.27
960
3026
2490
14338
5.31
294.69
20.8
8.7
5.35
4.19
e9/l
24.29
2319
12448
745
1875
4.95
280.88
9.9
3.9
1.05
0.37
%
1.11
361
526
1108
3784
4.05
278.58
2.6
2.5
2.42
2.29
g/l
11.69
1050
3487
1147
4079
3.93
270.87
2.7
2.5
13.29
12.59
umol/l
2.17
1093
3793
363
662
6.10
193.45
2.6
2.4
3.27
3.63
g/l
4.89
344
626
2164
13395
3.20
180.62
9.7
6.2
12.29
11.71
umol/l
1.15
2107
12686
1757
10083
2.79
161.51
3.8
2.8
146.94
141.62
ug/l
0.17
1633
9200
269
440
6.62
159.21
8.9
3.2
1.48
1.41
%
0.13
234
388
1756
10806
2.50
128.49
20.5
9.7
0.05
0.00
e9/l
3.97
1545
8801
423
1271
3.71
119.33
1.8
1.8
1.08
1.53
g/l
19.50
361
1090
1214
6711
2.36
107.47
2.6
2.2
4.95
3.02
mg/l
22.43
1042
5671
173
274
6.64
105.05
9.0
3.2
66.37
55.95
%
7.10
138
230
2525
19501
2.85
98.96
15.1
7.6
84.47
79.52
u/l
5.25
2457
18323
167
293
5.98
91.46
10.6
3.8
—
—
—
0
0
218
495
4.67
89.20
5.5
3.4
62.15
57.77
%
4.11
218
495
62
26
24.33
87.09
1.0
1.1
—
—
—
0
0
145
235
6.43
85.96
1.1
1.1
—
—
—
0
0
1884
13215
2.14
85.02
8.0
6.8
1.21
1.21
mmol/l
0.32
1590
11158
93
90
10.63
84.48
1.1
1.1
—
—
—
0
0
185
391
4.98
82.44
3.6
2.2
—
—
—
0
0
1267
7857
2.06
77.36
5.6
4.0
7.39
7.40
ph
3.46
256
1512
1063
6364
2.04
69.81
13.8
6.4
—
—
—
0
0
411
1646
2.73
69.39
5.0
3.2
7.01
5.27
e9/l
1.31
283
1285
1688
11998
1.93
65.74
7.3
6.0
1.22
1.21
mmol/l
5.41
1550
10870
1553
10978
1.86
59.01
2.4
2.1
91.83
94.16
pmol/l
1.14
945
5593
1032
6414
1.93
58.58
1.8
1.6
20.42
20.55
nmol/l
0.10
911
5405
210
628
3.52
58.49
3.4
2.8
1.35
1.63
mg/l
6.32
203
564
68
77
9.01
55.00
1.5
1.6
—
—
—
0
0
1001
6452
1.83
48.75
5.4
3.9
83.53
87.92
%
5.79
950
6288
1548
11377
1.74
47.59
6.1
4.7
35.58
35.05
g/l
3.27
1452
10562
241
884
2.88
47.46
2.7
1.9
22.55
21.57
s
0.68
213
784
534
2814
2.09
47.11
4.8
2.6
6.92
8.80
umol/l
1.87
482
2457
464
2320
2.18
46.89
2.8
2.6
66.90
66.31
g/l
0.89
421
2109
1920
15187
1.73
43.51
5.7
4.8
6.61
6.81
mmol/l
4.56
1850
14277
686
4052
1.90
43.26
2.7
2.0
32.04
29.93
s
11.48
648
3930
2220
18364
1.80
42.29
5.2
4.2
11.85
13.37
mm/h
4.46
2079
16899
395
1952
2.18
40.77
2.7
2.4
—
—
—
0
0
601
3472
1.91
40.23
4.9
5.6
1.07
1.03
mmol/l
1.85
560
3196
826
5377
1.74
36.89
2.0
1.7
1.15
1.34
mg/l
1.22
645
4161
687
4282
1.78
35.50
3.8
3.2
0.82
0.81
mmol/l
1.16
650
3994
356
1798
2.11
34.47
2.9
2.8
10.42
10.59
g/l
0.27
324
1632
803
5314
1.70
33.19
1.9
1.8
1085.84
1172.00
nmol/l
1.94
609
3968
214
912
2.45
31.01
3.5
3.5
37.81
70.23
mg/l
1.28
188
735
214
912
2.45
31.01
3.5
3.5
54.68
122.85
mg/l
0.53
187
735
291
1414
2.17
31.00
2.0
1.9
1.62
1.42
g/l
0.54
262
1280
209
884
2.47
30.78
3.5
3.5
1.64
1.73
ratio
0.06
22
71
237
1086
2.28
29.10
2.9
2.5
3.35
3.66
g/l
3.58
210
984
237
1088
2.28
28.97
2.9
2.5
6.93
7.41
g/l
4.74
211
985
223
1015
2.29
27.80
2.8
2.5
11.22
10.29
g/l
1.84
196
906
222
1018
2.27
27.19
3.0
2.5
3.01
2.95
g/l
0.40
195
916
1566
12620
1.50
25.83
21.4
17.0
1.39
1.31
inr
2.21
518
3619
189
857
2.29
23.74
3.0
2.3
38.62
37.66
g/l
1.41
163
754
37
60
6.23
21.91
1.0
1.0
—
—
—
0
0
2644
24263
1.75
21.58
26.2
15.7
20.26
25.28
mg/l
14.81
2273
19564
36
58
6.27
21.45
1.6
1.1
—
—
—
0
0
158
694
2.35
21.37
3.6
3.6
—
—
—
0
0
142
602
2.43
20.79
1.7
1.6
—
—
—
0
0
368
2228
1.74
20.07
3.2
3.9
1.22
1.23
mmol/l
1.63
316
1937
1073
8310
1.45
19.91
3.2
3.1
2213.90
1558.03
ng/l
2.10
930
7161
470
3068
1.63
19.25
1.3
1.3
414.85
525.24
titre
0.87
97
664
30
46
6.58
18.74
3.7
1.5
—
—
—
0
0
2292
20571
1.48
17.98
35.5
18.4
16.69
15.18
%
28.93
2275
20168
971
7495
1.44
17.88
5.8
4.3
—
—
—
0
0
22
7
31.64
17.02
1.0
1.0
—
—
—
0
0
22
7
31.64
17.02
1.0
1.0
—
—
—
0
0
22
7
31.64
17.02
1.0
1.0
—
—
—
0
0
22
7
31.64
17.02
1.0
1.0
—
—
—
0
0
22
7
31.64
17.02
1.0
1.0
—
—
—
0
0
995
7776
1.42
16.88
4.3
3.1
32.59
38.61
u/l
1.46
954
7371
2495
22871
1.54
16.88
5.1
4.1
1.30
1.30
mmol/l
0.07
2341
20561
378
2420
1.64
16.59
5.8
7.1
9.61
10.33
mmol/l
1.29
354
2292
25
36
6.99
16.53
1.5
1.4
—
—
—
0
0
602
4300
1.50
16.32
1.5
1.5
2.39
2.56
g/l
1.05
375
2543
95
378
2.56
15.97
1.3
1.4
157.86
119.42
u/ml
0.27
14
74
124
558
2.27
15.90
1.2
1.2
—
—
—
0
0
95
380
2.55
15.80
1.2
1.2
291.07
275.74
u/ml
0.17
60
222
362
2325
1.63
15.65
1.4
1.4
—
—
—
0
0
157
797
2.02
14.81
3.5
3.5
—
—
—
0
0
241
1409
1.77
14.73
1.3
1.4
—
—
—
0
0
346
2251
1.61
14.14
1.4
1.5
—
—
—
0
0
326
2097
1.62
13.95
4.5
4.1
—
—
—
0
0
99
431
2.34
13.75
1.3
1.3
—
—
—
0
0
1010
8144
1.36
13.47
5.0
2.4
—
—
—
0
0
426
2959
1.51
12.97
2.1
1.8
—
—
—
0
0
78
313
2.53
12.95
1.2
1.2
4.47
5.22
u/ml
0.15
38
134
377
2566
1.54
12.60
1.4
1.5
—
—
—
0
0
697
5341
1.40
12.57
3.1
2.9
535.61
536.08
mosm/kgh2o
0.02
615
4593
56
192
2.95
12.56
1.3
1.2
—
—
—
0
0
58
203
2.89
12.54
2.5
2.4
—
—
—
0
0
1723
15142
1.32
12.37
3.8
3.2
60.11
53.00
u/l
2.38
1631
13895
2689
25414
1.55
12.14
27.6
18.4
139.42
139.64
mmol/l
4.07
2648
24755
59
216
2.77
11.77
3.7
2.1
2.65
1.18
e9/l
0.41
51
196
875
7026
1.35
11.62
3.5
3.2
—
—
—
0
0
2691
25476
1.54
11.61
29.1
18.6
4.01
3.98
mmol/l
7.21
2646
24774
197
1166
1.74
11.55
2.1
1.9
1.33
2.56
ug/l
1.18
173
1017
802
6364
1.35
11.49
3.8
3.6
—
—
—
0
0
73
306
2.42
11.09
1.0
1.1
110.49
115.97
%
0.78
67
278
968
7937
1.32
11.02
3.6
3.3
59.71
78.91
e6/l
0.40
754
6153
1919
17258
1.31
10.95
4.8
4.5
—
—
—
0
0
2521
23623
1.42
10.89
5.6
4.6
1.31
1.46
mmol/l
56.30
2376
21443
1081
9013
1.31
10.88
3.1
3.4
2.34
2.35
mmol/l
2.36
940
7821
122
634
1.96
10.84
1.2
1.2
110.91
83.56
titre
0.35
11
45
48
166
2.92
10.65
2.2
2.0
71.58
71.64
%
0.01
43
155
80
356
2.28
10.64
1.1
1.1
—
—
—
0
0
2537
23823
1.42
10.61
5.6
4.6
4.17
4.58
mmol/l
79.75
2411
21776
44
146
3.04
10.50
4.1
2.1
1449.91
557.90
e6/l
0.50
35
124
70
298
2.38
10.31
2.4
1.9
—
—
—
0
0
324
2231
1.51
10.20
2.1
2.2
400.85
370.75
nmol/l
1.59
300
2022
889
7281
1.31
10.00
3.5
3.2
0.45
0.49
e6/l
0.17
688
5604
161
939
1.76
9.96
2.3
2.2
274.27
750.95
ug/l
1.39
153
882
42
140
3.03
9.96
4.4
2.1
0.20
0.23
e9/l
0.40
36
124
1391
12086
1.28
9.91
5.3
5.2
0.00
0.00
estimate
0.50
373
2269
1360
11788
1.28
9.87
4.8
2.6
—
—
—
0
0
1394
12120
1.28
9.87
4.0
3.9
0.00
0.00
estimate
0.99
401
2440
973
8079
1.30
9.86
2.1
2.1
137.55
224.21
u/l
4.46
906
7539
36
110
3.30
9.85
1.6
2.5
1561.42
1255.17
u/ml
0.21
36
110
2391
22320
1.35
9.66
5.4
4.8
2.05
2.11
mu/l
0.23
2231
20172
1402
12240
1.27
9.44
3.9
3.9
0.00
0.00
estimate
1.08
375
2203
27
70
3.88
9.40
1.3
1.1
—
—
—
0
0
772
6248
1.32
9.35
5.0
2.3
—
—
—
0
0
353
2518
1.46
9.29
2.0
2.1
0.20
0.21
g/l
0.50
318
2341
2019
18463
1.29
9.16
4.4
4.0
15.12
14.94
pmol/l
2.21
1839
16574
180
1109
1.66
9.14
1.2
1.2
—
—
—
0
0
79
374
2.14
9.09
1.1
1.0
—
—
—
0
0
697
5580
1.32
9.08
2.9
2.6
4.86
5.37
e6/l
0.54
639
5021
40
137
2.95
9.08
1.6
2.8
33.00
41.53
%
1.34
16
85
254
1702
1.54
9.07
3.9
3.7
5.20
5.17
kpa
0.19
229
1609
1206
10376
1.27
9.03
2.5
2.2
78.71
78.80
nmol/l
0.04
1066
9130
18
20
9.05
9.02
1.3
1.5
—
—
—
0
0
119
656
1.85
8.91
1.5
1.6
0.22
0.24
g/l
1.35
107
626
380
2773
1.42
8.84
5.0
4.5
—
—
—
0
0
1183
10185
1.27
8.71
4.3
3.9
47.56
99.91
ng/l
0.64
920
7499
640
5089
1.33
8.70
3.3
3.1
2.44
2.46
mmol/l
2.69
553
4469
2571
24369
1.38
8.67
6.1
5.2
2.39
2.68
mmol/l
54.65
2435
22158
236
1573
1.54
8.64
6.5
7.0
24.68
24.96
mmol/l
0.46
236
1565
249
1681
1.52
8.60
3.9
3.7
7.41
7.41
ph
0.15
29
208
404
2996
1.40
8.56
1.5
1.6
—
—
—
0
0
121
680
1.81
8.53
1.4
1.5
1.13
1.18
g/l
1.27
110
647
481
3682
1.36
8.40
2.1
2.0
—
—
—
0
0
1071
9144
1.27
8.37
4.2
3.8
115.75
115.51
e6/l
0.00
793
6584
213
1399
1.56
8.33
2.8
3.2
4.36
4.41
pmol/l
0.41
174
1216
113
628
1.83
8.27
1.8
1.9
15.46
11.99
mg/l
0.92
98
577
949
8032
1.27
7.87
2.9
2.6
53.84
69.52
u/l
0.92
867
7391
2688
25744
1.42
7.86
22.4
10.9
25.28
25.73
u/l
0.73
2635
24717
94
501
1.90
7.85
1.2
1.4
57.49
60.88
mmol/l
0.41
76
398
73
357
2.07
7.77
6.9
6.7
11.58
12.00
mg/l
0.35
67
332
27
81
3.35
7.65
1.3
1.2
—
—
—
0
0
2412
22764
1.30
7.46
6.4
6.2
38.48
40.42
mmol/mol
21.85
2272
20832
384
2909
1.37
7.12
1.9
1.4
—
—
—
0
0
107
615
1.77
7.05
4.7
4.8
8.19
8.44
kpa
0.74
107
607
105
611
1.74
6.65
4.6
4.7
2.65
2.77
mmol/l
0.15
73
425
105
612
1.74
6.62
4.7
4.8
5.03
5.07
kpa
0.20
105
605
1111
9714
1.23
6.59
3.5
3.6
5.61
5.82
ph
0.80
53
543
99
571
1.76
6.48
2.6
2.5
16.38
15.97
%
0.28
48
290
451
3548
1.32
6.47
1.3
1.2
—
—
—
0
0
17
32
5.34
6.14
1.1
1.4
8.88
5.66
nmol/l
0.46
12
26
16
28
5.74
6.14
1.1
1.0
—
—
—
0
0
29
105
2.78
6.05
41.0
26.2
118.31
114.62
ug/l
0.14
29
87
27
94
2.89
6.04
2.6
2.0
—
—
—
0
0
34
135
2.54
5.94
2.0
1.5
—
—
—
0
0
633
5258
1.26
5.90
3.8
3.9
632.69
559.84
ng/l
0.06
512
4308
68
360
1.91
5.88
1.1
1.1
—
—
—
0
0
19
54
3.53
5.88
1.1
1.1
—
—
—
0
0
100
607
1.67
5.50
3.6
3.9
—
—
—
0
0
771
6592
1.23
5.48
4.3
4.3
0.00
0.00
estimate
1.08
364
2174
87
509
1.73
5.47
2.9
2.8
—
—
—
0
0
132
861
1.56
5.42
1.2
1.2
0.21
0.78
u/ml
—
7
72
956
8370
1.21
5.33
3.4
3.4
—
—
—
0
0
18
53
3.41
5.30
1.2
1.2
—
—
—
0
0
305
2335
1.34
5.28
2.3
2.4
32.76
38.93
u/l
1.45
262
2002
1803
16761
1.19
5.03
5.1
4.8
2966.91
2033.04
e6/l
0.14
22
260
396
3166
1.29
5.01
7.2
7.1
11.86
12.01
kpa
0.17
379
3010
396
3166
1.29
5.01
7.2
7.1
5.00
5.11
kpa
1.50
380
3010
2482
23789
1.25
5.00
5.2
4.9
5.96
6.02
mmol/l
1.47
2264
21419
309
2393
1.32
4.95
6.0
6.6
1.45
1.38
mmol/l
0.38
303
2339
174
1227
1.44
4.93
4.4
3.8
—
—
—
0
0
292
2247
1.33
4.89
7.0
7.9
—
—
—
0
0
112
726
1.56
4.77
4.5
4.4
7.42
7.42
ph
0.01
106
659
20
68
2.95
4.71
1.5
1.3
—
—
—
0
0
355
2829
1.29
4.61
7.6
7.4
94.91
95.43
%
0.65
344
2718
244
1846
1.35
4.58
5.3
4.7
—
—
—
0
0
325
2562
1.30
4.58
3.4
3.4
5.74
5.84
kpa
1.06
316
2485
149
1036
1.46
4.57
4.4
4.0
24.46
24.90
mmol/l
0.98
132
952
58
319
1.83
4.55
1.3
1.4
74.25
47.88
mu/l
0.30
48
283
38
180
2.13
4.53
1.1
1.2
140.00
117.27
titre
—
5
33
15
44
3.42
4.46
1.4
1.9
83.75
211.88
e6/l
—
8
16
1882
17645
1.18
4.46
4.5
4.1
—
—
—
0
0
17
55
3.10
4.36
1.5
1.3
—
127.33
titre
—
0
9
322
2553
1.29
4.35
3.4
3.4
1.61
2.05
mmol/l
1.18
267
2138
389
3160
1.27
4.33
7.3
7.1
1.09
1.18
mmol/l
0.14
310
2501
69
410
1.70
4.19
1.1
1.3
—
—
—
0
0
11
21
5.25
4.14
1.0
1.2
184.82
145.81
mmol/l
0.35
11
16
1114
10061
1.17
4.10
2.3
2.2
—
—
—
0
0
21
80
2.64
4.06
2.3
2.0
—
—
—
0
0
267
2101
1.30
3.84
3.3
3.7
87.03
94.49
ng/l
0.75
227
1785
53
302
1.77
3.76
1.2
1.5
—
—
—
0
0
34
170
2.01
3.59
1.5
1.1
—
—
—
0
0
15
51
2.95
3.57
1.1
1.1
—
—
—
0
0
33
164
2.02
3.54
4.4
3.8
—
—
—
0
0
339
2778
1.25
3.51
1.2
1.3
—
—
—
0
0
492
4193
1.21
3.49
3.3
3.0
1.66
2.47
e6/l
1.81
252
2309
17
63
2.71
3.49
1.1
1.0
—
—
—
0
0
73
464
1.59
3.47
2.3
3.1
—
—
—
0
0
18
69
2.62
3.47
1.1
1.1
—
—
—
0
0
14
47
2.99
3.41
1.1
1.1
—
—
—
0
0
66
1019
0.64
3.25
1.6
1.5
—
—
—
0
0
87
587
1.50
3.20
1.2
1.2
1.76
3.85
u/ml
—
5
57
88
597
1.49
3.15
1.2
1.2
3.90
7.77
u/ml
—
8
105
152
1139
1.35
3.13
4.5
5.3
1.96
1.60
%
1.56
140
1065
53
321
1.66
3.09
1.3
1.2
—
—
—
0
0
55
337
1.64
3.07
1.7
1.6
0.86
0.84
g/l
0.04
40
252
876
7910
1.15
3.05
4.5
4.1
—
—
—
0
0
738
6581
1.16
3.05
1.6
1.6
1.43
1.36
mmol/l
1.29
632
5455
35
190
1.85
2.97
1.5
2.5
—
—
—
0
0
314
2608
1.23
2.90
8.2
7.8
119.79
121.18
g/l
0.47
305
2531
220
1756
1.27
2.89
1.2
1.2
—
—
—
0
0
49
298
1.65
2.84
1.1
1.3
301.79
313.19
pmol/l
0.09
38
259
82
562
1.47
2.83
2.3
2.9
38.93
36.72
umol/l
0.21
74
499
50
306
1.64
2.83
3.2
2.2
1.34
1.43
g/24h
0.07
30
149
52
322
1.63
2.81
1.2
1.4
130781.31
93736.84
e6/l
0.23
32
192
9
23
3.92
2.77
1.0
1.0
—
—
—
0
0
2718
26609
1.23
2.73
45.7
23.0
402.80
245.65
e9/l
307.65
2673
25868
166
1288
1.31
2.73
1.4
1.3
—
—
—
0
0
458
3967
1.18
2.72
1.3
1.3
27.22
37.72
iu/ml
1.25
143
1274
46
279
1.66
2.70
1.3
1.2
—
—
—
0
0
60
389
1.55
2.70
2.5
2.6
—
—
—
0
0
2718
26615
1.22
2.69
45.4
23.0
93.77
91.41
fl
24.59
2694
26159
2718
26616
1.22
2.68
45.3
22.9
30.61
30.38
pg
1.85
2694
26157
2718
26617
1.22
2.67
45.6
23.0
8.96
6.80
e9/l
33.54
2664
25780
61
398
1.54
2.67
1.2
1.5
31.35
32.10
g/l
0.20
53
362
2718
26618
1.22
2.67
45.6
23.0
4.44
4.44
e12/l
0.00
2661
25785
2716
26597
1.22
2.66
45.5
23.1
40.28
39.74
%
3.99
2567
24688
19
86
2.22
2.63
2.2
2.0
1335.85
23277.38
e6/l
0.54
13
50
2718
26624
1.22
2.62
45.9
23.2
132.14
134.09
g/l
7.20
2694
26175
36
206
1.76
2.61
1.6
1.8
—
—
—
0
0
555
4900
1.16
2.60
1.3
1.2
2.10
1.46
u/ml
0.37
104
1238
512
4498
1.17
2.55
3.1
2.8
0.92
1.22
e6/l
1.14
271
2597
16
68
2.36
2.55
1.3
1.4
—
—
—
0
0
29
157
1.86
2.52
2.7
3.0
—
—
—
0
0
26
136
1.92
2.50
1.3
1.3
1.37
1.18
nmol/l
0.42
17
107
35
202
1.74
2.48
1.3
1.2
—
—
—
0
0
2561
24980
1.17
2.45
24.1
15.0
—
—
—
0
0
30
166
1.82
2.44
1.2
1.1
—
—
—
0
0
67
456
1.48
2.44
1.8
1.9
4.98
4.86
mmol/24h
0.10
62
381
310
2621
1.20
2.42
2.3
2.2
187.21
153.35
ug/g
0.51
248
2055
26
140
1.86
2.31
1.2
1.3
—
—
—
0
0
434
3794
1.17
2.31
1.2
1.2
10.67
13.04
u/ml
0.32
151
1409
15
65
2.31
2.31
2.4
1.9
—
—
—
0
0
292
2470
1.20
2.28
3.3
3.0
223.31
221.65
ng/l
0.02
268
2245
7
18
3.90
2.25
1.0
1.0
—
—
—
0
0
7
18
3.90
2.25
1.0
1.0
—
—
—
0
0
5
9
5.56
2.21
2.6
1.3
—
—
—
0
0
27
151
1.80
2.16
1.5
1.5
0.98
0.97
g/l
0.02
27
151
251
2106
1.21
2.15
2.9
2.9
4.56
4.54
kpa
0.04
245
2035
143
1127
1.28
2.15
4.7
5.3
0.93
0.88
%
0.60
131
1055
45
290
1.56
2.14
1.3
1.3
272.97
276.84
mosm/kgh2o
0.53
38
220
54
363
1.50
2.12
1.2
1.4
1913.03
1760.23
e6/l
0.11
37
265
8
25
3.21
2.09
2.1
1.1
—
—
—
0
0
8
25
3.21
2.09
2.1
1.1
—
—
—
0
0
8
25
3.21
2.09
2.1
1.1
—
—
—
0
0
25
139
1.81
2.05
1.0
1.1
—
—
—
0
0
28
162
1.74
2.02
2.5
1.6
—
—
—
0
0
112
1437
0.77
1.98
1.4
1.4
—
—
—
0
0
61
428
1.43
1.96
2.7
2.4
—
—
—
0
0
19
98
1.94
1.95
2.2
2.2
560.38
776.05
e6/l
0.43
13
76
9
33
2.73
1.93
1.2
1.2
—
—
—
0
0
46
306
1.51
1.93
1.1
1.2
—
—
—
0
0
37
569
0.65
1.92
1.2
1.2
—
—
—
0
0
46
308
1.50
1.88
1.2
1.2
—
—
nmol/l
—
0
0
15
72
2.09
1.86
1.1
1.3
—
—
—
0
0
46
309
1.50
1.85
1.3
1.6
—
—
—
0
0
34
213
1.60
1.85
1.1
1.4
—
—
—
0
0
6
17
3.53
1.83
1.0
1.0
—
—
—
0
0
5
12
4.17
1.82
1.0
1.0
46.06
35.23
s
—
5
12
19
101
1.89
1.80
1.3
1.2
—
—
—
0
0
18
95
1.90
1.75
2.1
1.8
45.38
48.43
ug/l
0.21
18
90
178
1479
1.22
1.73
9.3
9.8
—
—
—
0
0
23
132
1.75
1.73
1.0
1.0
—
—
—
0
0
7
24
2.92
1.72
1.0
1.1
—
—
—
0
0
41
274
1.50
1.71
1.8
2.9
—
—
—
0
0
33
210
1.58
1.70
1.1
1.4
2.57
2.87
g/l
0.45
21
143
33
210
1.58
1.70
1.1
1.4
6.81
7.18
g/l
0.19
22
143
33
210
1.58
1.70
1.1
1.4
0.41
0.42
g/l
0.03
21
143
39
259
1.51
1.68
1.0
1.1
—
—
—
0
0
7
25
2.80
1.65
2.3
2.8
0.43
0.76
u/field
—
7
25
6
147
0.41
1.64
1.0
1.1
—
—
—
0
0
22
128
1.72
1.60
1.5
2.4
—
—
—
0
0
7
26
2.70
1.58
1.3
2.0
—
—
—
0
0
61
448
1.37
1.57
1.4
1.3
12.69
10.20
u/l
0.88
53
360
7
27
2.60
1.51
1.0
1.1
—
—
—
0
0
17
93
1.83
1.51
1.4
1.5
4.61
3.29
%
0.18
17
77
78
599
1.31
1.51
1.2
1.1
15.76
6.10
u/ml
—
9
54
368
3288
1.14
1.49
5.2
4.7
31.59
33.13
%
2.16
287
2150
6
22
2.73
1.43
1.7
2.6
—
—
—
0
0
163
1376
1.20
1.40
3.2
3.2
24.64
25.29
mmol/l
1.47
155
1333
93
740
1.26
1.39
1.2
1.2
—
—
—
0
0
18
104
1.74
1.36
2.1
2.5
—
—
—
0
0
33
223
1.49
1.36
1.4
1.2
334.71
359.35
nmol/l
0.29
28
191
368
3320
1.12
1.30
1.3
1.3
—
—
—
0
0
200
1731
1.17
1.30
8.8
6.8
24.22
24.60
mmol/l
0.69
190
1640
37
262
1.42
1.22
1.4
1.7
—
1220.00
—
0
8
11
56
1.97
1.22
1.4
1.5
—
—
—
0
0
40
289
1.39
1.19
1.2
1.4
—
—
—
0
0
47
349
1.35
1.19
2.5
2.5
—
—
—
0
0
623
5805
1.09
1.19
1.6
1.7
22245811.17
26287465.83
pmol/l
0.06
481
4759
14
79
1.78
1.17
1.0
1.3
57.24
466.17
ug/l
—
9
39
40
291
1.38
1.15
4.2
3.5
—
—
—
0
0
25
166
1.51
1.14
1.2
1.3
—
—
—
0
0
75
599
1.26
1.13
2.3
2.2
131.65
127.96
g/l
0.41
60
434
9
164
0.55
1.08
1.6
1.4
—
—
—
0
0
9
164
0.55
1.08
1.6
1.4
—
—
—
0
0
82
668
1.23
1.06
3.5
3.2
0.78
0.81
nmol/l
0.27
62
520
40
296
1.36
1.06
7.5
6.9
7.68
7.62
mmol/l
0.04
33
251
49
375
1.31
1.04
1.2
1.3
—
—
—
0
0
88
725
1.22
1.03
4.3
4.6
—
—
—
0
0
13
75
1.74
1.02
2.6
1.9
—
—
—
0
0
43
324
1.33
1.02
1.4
1.8
—
—
—
0
0
22
147
1.50
1.00
1.5
2.2
—
—
—
0
0
160
1395
1.16
0.99
1.2
1.2
105.42
142.89
iu/ml
0.78
55
505
24
164
1.47
0.99
2.0
1.6
—
—
—
0
0
70
566
1.24
0.98
1.9
1.8
41.52
42.08
nmol/l
0.08
65
537
183
1615
1.14
0.97
2.5
2.4
17.74
24.68
au/ml
0.35
17
97
79
652
1.22
0.93
1.4
1.3
25.66
31.12
iu/l
1.01
72
554
10
55
1.82
0.92
1.8
1.3
—
—
—
0
0
165
1453
1.14
0.91
1.3
1.3
46.44
58.69
au/ml
—
9
76
10
170
0.59
0.89
1.5
1.5
—
—
—
0
0
49
386
1.27
0.88
1.4
2.0
—
—
—
0
0
99
841
1.18
0.88
1.6
1.6
—
—
—
0
0
160
1412
1.14
0.87
3.6
3.6
—
—
—
0
0
151
1329
1.14
0.85
1.3
1.3
163.57
217.51
u/ml
0.61
142
1218
163
1443
1.14
0.85
2.4
2.5
—
—
—
0
0
16
104
1.54
0.84
1.1
1.8
2.45
6.26
ug/l
—
9
80
1936
19762
0.94
0.83
40.6
20.4
325.97
331.85
g/l
56.70
1923
19588
91
772
1.18
0.83
1.4
1.4
293.66
279.54
ug/g
0.31
56
452
38
292
1.31
0.83
1.5
1.5
—
—
—
0
0
667
6327
1.07
0.82
1.4
1.3
—
—
—
0
0
47
589
0.79
0.82
1.4
1.3
—
—
—
0
0
21
146
1.44
0.82
3.1
2.7
7.44
7.42
ph
—
8
47
13
81
1.61
0.81
1.2
1.2
38.14
38.65
g/l
—
7
40
52
642
0.81
0.80
1.0
1.1
—
—
—
0
0
58
473
1.23
0.80
1.5
1.5
—
—
—
0
0
243
2217
1.10
0.77
1.5
1.5
—
—
—
0
0
271
2493
1.10
0.74
2.3
2.4
5.13
7.11
ug/l
2.14
211
2175
188
1698
1.11
0.73
2.7
3.0
127.84
127.88
g/l
0.01
179
1654
5
25
2.00
0.72
1.0
1.1
—
—
—
0
0
23
168
1.37
0.71
1.0
1.1
35.44
42.51
mg/l
0.58
18
139
5
26
1.92
0.70
4.8
4.8
55.40
62.05
ug/min
—
5
21
5
26
1.92
0.70
1.4
1.3
—
640.53
—
0
9
15
217
0.69
0.70
1.0
1.0
—
—
—
0
0
478
5057
0.93
0.69
2.8
3.1
0.76
0.77
ug/l
0.09
325
3477
125
1109
1.13
0.67
2.4
2.6
—
—
—
0
0
35
276
1.27
0.66
1.2
1.0
2.97
2.12
u/ml
0.38
11
100
614
5854
1.06
0.66
3.5
3.8
—
—
—
0
0
22
162
1.36
0.66
1.3
1.3
9.25
9.83
mmol/l
0.28
22
155
13
86
1.51
0.66
1.3
1.4
17.52
23.75
%
0.48
13
78
505
5324
0.94
0.66
4.3
4.4
1.02
1.02
kg/l
0.37
75
797
72
615
1.17
0.65
6.9
7.2
11.86
11.13
mmol/l
0.95
63
548
10
62
1.61
0.65
2.8
2.4
—
—
—
0
0
15
103
1.46
0.65
2.0
2.0
79.11
102.41
umol/l
—
9
58
125
1113
1.13
0.64
6.2
4.4
—
—
—
0
0
72
616
1.17
0.64
6.9
7.2
104.92
105.14
mmol/l
0.14
63
549
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
27
207
1.31
0.63
4.8
4.8
53.59
40.79
u/ml
0.18
11
57
8
49
1.63
0.62
1.4
1.5
—
—
—
0
0
33
413
0.80
0.62
1.6
1.7
—
—
—
0
0
23
173
1.33
0.61
1.1
1.2
—
—
—
0
0
5
30
1.67
0.61
2.6
2.4
10.76
17.35
umol/l
—
5
30
206
2238
0.91
0.60
3.7
3.5
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
132
1186
1.12
0.60
1.5
1.5
—
—
—
0
0
112
997
1.13
0.59
2.3
3.2
452.18
5013.65
u/ml
0.93
96
847
8
52
1.54
0.59
1.1
1.1
—
—
—
0
0
11
72
1.53
0.59
1.5
1.2
23.60
18.27
%
—
5
11
71
820
0.86
0.58
18.7
10.5
—
—
—
0
0
6
35
1.72
0.57
1.0
1.2
2.65
1.88
umol/24h
—
6
35
104
925
1.13
0.56
3.3
3.0
0.31
0.28
g/l
0.22
44
341
6
36
1.67
0.56
1.5
1.2
29.85
32.66
nmol/l
—
6
28
19
141
1.35
0.56
6.9
6.3
—
—
—
0
0
197
1816
1.09
0.55
1.4
1.4
—
—
—
0
0
50
421
1.19
0.55
1.4
2.0
—
—
—
0
0
22
168
1.31
0.55
1.1
1.1
—
—
—
0
0
8
123
0.65
0.54
2.6
4.2
—
—
—
0
0
50
422
1.19
0.54
1.4
1.9
—
—
—
0
0
40
331
1.21
0.53
1.2
1.3
—
—
—
0
0
11
74
1.49
0.53
1.0
1.1
—
—
—
0
0
12
170
0.70
0.53
1.0
1.5
112.17
85.12
umol/l
0.56
12
170
50
424
1.18
0.52
1.4
1.9
—
—
—
0
0
6
40
1.50
0.51
1.0
1.2
—
—
—
0
0
15
109
1.38
0.51
1.1
1.3
—
—
—
0
0
181
1673
1.09
0.49
2.8
2.2
12.74
12.65
nmol/l
0.05
160
1467
94
840
1.12
0.49
6.3
3.9
3.96
3.89
mmol/l
0.69
94
832
19
145
1.31
0.48
1.1
1.4
—
—
—
0
0
27
218
1.24
0.46
2.3
2.2
671.06
624.26
ml
0.27
16
141
80
894
0.89
0.44
1.8
1.7
—
—
—
0
0
31
256
1.21
0.44
1.3
1.4
—
—
—
0
0
10
69
1.45
0.44
1.0
1.0
—
—
—
0
0
7
51
1.37
0.44
6.6
7.5
—
—
—
0
0
38
321
1.19
0.43
1.1
1.1
—
10.49
—
0
16
17
131
1.30
0.42
1.8
2.5
2131.18
1891.49
ml
0.37
17
111
11
79
1.39
0.40
1.2
1.5
—
—
—
0
0
48
417
1.15
0.40
1.5
1.9
—
—
—
0
0
20
159
1.26
0.40
2.1
1.8
6.37
11.00
umol/l
0.52
14
101
20
159
1.26
0.40
2.3
2.0
486.58
489.16
min
0.04
12
116
0
19
0.00
0.39
0.0
2.0
—
—
—
0
0
28
233
1.20
0.38
1.2
1.5
22.15
28.36
%
0.46
14
145
18
142
1.27
0.38
7.4
13.9
—
—
—
0
0
9
68
1.32
0.37
3.4
2.0
—
—
—
0
0
15
116
1.29
0.37
1.0
1.0
—
—
—
0
0
33
385
0.86
0.36
1.1
1.1
74.00
100.57
iu/ml
—
6
81
5
77
0.65
0.35
3.0
2.4
154.80
143.17
nmol/l
—
5
66
30
352
0.85
0.35
2.9
4.8
348.09
350.03
umol/l
0.03
23
304
95
872
1.09
0.34
6.5
6.2
1.42
1.32
mmol/l
0.30
84
765
6
46
1.30
0.33
1.8
1.1
—
—
—
0
0
67
607
1.11
0.32
1.4
1.1
—
—
—
0
0
899
8804
1.03
0.31
4.5
5.2
2.39
3.60
ug/l
1.56
790
7825
17
138
1.23
0.30
1.6
1.5
145.23
160.79
pmol/l
0.13
17
138
18
217
0.83
0.29
1.2
1.8
12.32
11.22
%
0.44
18
217
781
7650
1.03
0.27
3.8
3.1
—
—
—
0
0
59
539
1.10
0.26
1.3
1.4
35.96
28.97
e6/l
0.12
47
412
59
539
1.10
0.26
1.4
1.4
1063.04
1393.97
e6/l
0.13
50
435
35
310
1.13
0.26
1.5
1.2
—
—
—
0
0
63
686
0.92
0.26
1.1
1.1
—
—
—
0
0
55
501
1.10
0.25
1.2
1.4
—
—
—
0
0
21
179
1.17
0.25
1.9
2.5
—
—
—
0
0
15
124
1.21
0.24
1.7
1.5
—
—
—
0
0
28
246
1.14
0.23
1.1
1.5
—
—
—
0
0
152
1594
0.95
0.23
1.2
1.2
—
—
—
0
0
5
39
1.28
0.23
1.4
1.3
42.02
74.43
%
—
5
34
12
97
1.24
0.23
1.2
1.3
104.95
164.00
mmol/24h
2.61
12
97
35
314
1.12
0.22
1.3
1.5
69.98
61.60
%
0.62
19
194
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
6.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
0.21
—
0
5
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
0.30
—
0
6
0
14
0.00
0.20
0.0
1.1
—
0.22
—
0
5
31
278
1.12
0.20
3.3
2.0
—
—
—
0
0
11
90
1.22
0.19
1.2
2.0
26.42
105.60
ug/l
0.43
11
80
14
118
1.19
0.19
1.3
1.4
1.44
1.57
g/l
1.56
14
118
22
248
0.89
0.18
1.1
1.0
0.91
4.30
u/ml
2.98
14
113
7
61
1.15
0.17
1.7
1.3
—
—
—
0
0
7
62
1.13
0.17
1.0
1.0
—
—
—
0
0
7
62
1.13
0.17
1.0
1.0
—
—
—
0
0
7
62
1.13
0.17
1.0
1.0
—
—
—
0
0
177
1709
1.04
0.17
3.3
3.2
—
—
—
0
0
52
557
0.93
0.17
1.3
1.9
2.74
4.73
iu/l
2.12
17
185
121
1160
1.04
0.16
2.0
1.9
—
—
—
0
0
85
808
1.05
0.16
1.0
1.1
—
—
—
0
0
9
78
1.15
0.15
1.0
1.1
1750.89
1666.65
miu/ml
—
9
78
39
361
1.08
0.15
1.4
2.0
15413.76
1911.54
u/l
—
8
146
7
87
0.80
0.14
1.3
1.6
—
—
—
0
0
17
150
1.13
0.14
1.9
2.1
19.40
180.68
ug/min
—
5
34
30
275
1.09
0.14
1.4
1.1
—
—
—
0
0
30
275
1.09
0.14
1.4
1.1
—
—
—
0
0
63
597
1.06
0.14
2.1
3.3
50.56
796.02
u/ml
1.06
53
549
300
2938
1.02
0.13
2.9
4.0
11.53
23.40
ug/l
0.73
224
2416
151
1465
1.03
0.12
1.2
1.3
—
—
—
0
0
17
189
0.90
0.12
1.1
1.0
1.59
2.35
u/ml
—
9
84
18
162
1.11
0.11
1.9
1.3
0.39
1.42
u/ml
0.94
13
91
61
639
0.95
0.11
1.5
1.6
12033.50
13992.11
e6/l
0.22
44
449
49
465
1.05
0.11
1.2
1.2
197.81
217.13
miu/ml
0.11
16
186
19
173
1.10
0.10
1.3
1.4
1.32
1.12
promille
0.19
11
134
806
7995
1.01
0.09
3.1
3.3
1232.44
294.99
mg/l
2.54
499
5087
25
268
0.93
0.09
1.2
1.2
—
—
—
0
0
6
56
1.07
0.08
6.2
4.7
—
—
—
0
0
6
58
1.03
0.08
1.8
1.5
—
—
—
0
0
5
63
0.79
0.08
1.2
1.5
—
—
—
0
0
69
714
0.97
0.08
2.6
2.7
—
—
—
0
0
20
185
1.08
0.08
1.1
1.2
—
—
—
0
0
7
66
1.06
0.08
1.3
1.5
—
—
—
0
0
41
428
0.96
0.07
1.5
1.4
—
—
—
0
0
20
214
0.93
0.07
1.5
1.5
0.26
0.28
nmol/l
0.10
14
165
19
177
1.07
0.06
1.1
1.4
—
—
—
0
0
60
582
1.03
0.06
4.4
3.7
29.47
26.65
mg/l
0.23
36
365
16
172
0.93
0.06
1.1
1.1
3.53
2.75
u/ml
—
8
65
23
218
1.06
0.05
1.0
1.0
2.29
0.96
u/ml
0.30
13
105
10
110
0.91
0.05
1.2
1.3
13.04
23.42
umol/l
—
10
104
27
281
0.96
0.04
1.1
1.1
0.19
1.47
u/ml
2.59
14
145
23
220
1.05
0.03
1.2
1.4
30.22
29.51
u/l
0.04
17
178
26
250
1.04
0.03
1.2
1.2
—
—
—
0
0
18
171
1.05
0.03
1.8
2.1
2.46
2.00
ug/l
0.36
18
148
65
662
0.98
0.03
2.6
2.2
159.74
101.39
ug/min
0.35
37
403
846
8438
1.00
0.02
3.6
3.8
12.64
8.80
mg/mmol
1.01
511
5289
58
571
1.02
0.02
1.7
2.6
—
—
—
0
0
13
123
1.06
0.01
2.1
1.2
207.46
137.50
nmol/l
1.60
13
123
15
143
1.05
0.01
1.1
1.0
—
—
—
0
0
31
303
1.02
0.01
3.2
2.6
—
—
—
0
0
10
95
1.05
0.00
3.0
2.4
—
—
—
0
0
10
95
1.05
0.00
1.2
1.4
3.19
3.18
mmol/l
—
10
85
18
175
1.03
0.00
1.8
2.0
5.20
3.12
ug/l
0.56
18
161
11
109
1.01
0.00
1.0
1.1
—
—
—
0
0
24
241
1.00
0.00
1.0
1.1
0.13
1.30
u/ml
—
10
97
52
519
1.00
0.00
1.3
1.8
0.79
0.81
nmol/l
0.06
44
425
24
236
1.02
0.00
2.0
2.0
3.50
2.02
u/field
0.52
12
87
825
8248
1.00
0.00
3.0
3.2
7.12
7.24
mmol/l
0.31
683
6859
243
2427
1.00
0.00
1.5
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
2.43
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
88
0.91
-0.00
1.1
1.3
—
—
—
0
0
6
61
0.98
-0.00
1.0
1.1
—
0.34
u/ml
—
0
15
5
53
0.94
-0.00
10.4
2.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
7
71
0.99
-0.00
2.0
1.6
87.14
180.14
nmol/24h
—
7
71
0
9
0.00
-0.00
0.0
5.9
—
13.51
—
0
9
43
430
1.00
-0.00
1.3
1.4
—
—
—
0
0
7
77
0.91
-0.00
1.6
1.3
26.86
24.50
%
—
7
62
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
2984.00
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
1270.00
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
211.18
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1745.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
1.62
—
0
5
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: MYELOPROF_NONCML – Myeloproliferative diseases (CML excluded)

GWS hits: 23

This endpoint is excluded (different definition than used in FinnGen).