Myeloproliferative diseases (CML excluded)

MYELOPROF_NONCML

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

  • not CML
519893

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D75.2

1 out of 7 registries used, show all original rules.

900

4. Check minimum number of events

None

900

5. Include endpoints

2861

6. Filter based on genotype QC (FinnGen only)

2861

Control definitions (FinnGen only)

Control conditions
not CML

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 2861 1515 1346
Unadjusted period prevalence (%) 0.55 0.52 0.59
Median age at first event (years) 63.63 62.23 65.21

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2298
Matched controls
22979
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
TPH00
NOMESCO Finland
Phlebotomy
358.4
323.0
361
12
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
110.3
323.0
1508
390
XW000
NOMESCO Finland
Bone marrow biopsy
24.9
323.0
710
405
L01XX05
ATC
hydroxycarbamide; oral
1989.7
323.0
1307
15
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
16384.0
323.0
1146
*
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
4522.6
323.0
390
*
D45
ICD-10 Finland
Polycythaemia vera
4555.2
323.0
1088
*
D75.2
ICD-10 Finland
Essential thrombocytosis
341.6
323.0
605
24
9962/3-C42.1
ICD-O-3
Essential thrombocythemia of bone marrow
+∞
323.0
359
*
9950/3-C42.1
ICD-O-3
Polycythemia vera of bone marrow
+∞
323.0
309
*
SPAT1074
SPAT
Venesection
214.6
260.7
266
14
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
33.6
208.5
276
93
L01XX35
ATC
anagrelide; oral
+∞
197.8
187
*
L03AB05
ATC
interferon alfa-2b; parenteral
180.4
191.0
198
12
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
1947.0
179.5
172
*
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
82.1
174.7
196
26
9960/3-C42.1
ICD-O-3
Myeloproliferative neoplasm, NOS, of bone marrow
1275.4
125.2
121
*
L03AB04
ATC
interferon alfa-2a; parenteral
255.2
119.1
121
5
B99
ICPC
Blood/lymph/spleen disease other
50.5
106.7
129
27
174
Kela drug reimbursment
Ruxolitinib
+∞
97.6
93
*
M04AA01
ATC
allopurinol; systemic
3.3
89.9
541
1970
374
Kela drug reimbursment
Ruxolitinib
+∞
84.9
81
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.3
83.7
499
1794
D75.1
ICD-10 Finland
Secondary polycythaemia
34.7
79.0
103
31
L01XE18
ATC
[U] ruxolitinib; oral
+∞
71.2
68
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.7
69.0
339
1036
L01EJ01
ATC
ruxolitinib; oral
+∞
63.8
61
*
212
Kela drug reimbursment
Gout
7.6
55.9
135
186
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
36.8
47.7
61
17
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
29.9
47.6
64
22
XX7BT
NOMESCO Finland
Radioactive phosphorus therapy
414.8
41.3
41
*
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
16.8
40.0
64
39
D75.0
ICD-10 Finland
Familial erythrocytosis
53.2
39.6
47
9
WW500
NOMESCO Finland
Blood transfusion
3.8
37.6
167
461
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
8.3
37.6
85
106
B28
ICPC
Limited function/disability (B)
19.8
37.1
56
29
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
15.4
36.2
60
40
B74
ICPC
Malignant neoplasm blood other
37.3
34.7
44
12
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
33.2
1080
7828
L03AA04
ATC
NA
49.5
32.6
39
8
B04
ICPC
Blood symptom/complaint
18.5
31.8
49
27
B03XA02
ATC
darbepoetin alfa; parenteral
5.7
30.8
91
166
B01AB05
ATC
enoxaparin; parenteral
1.7
28.4
754
5078
B01AC14
ATC
[U] anagrelide; oral
+∞
26.1
25
*
D75.8
ICD-10 Finland
Other specified diseases of blood and blood-forming organs
50.6
25.3
30
6
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
15.4
25.1
41
27
2384A
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Polycythaemia vera
+∞
24.0
23
*
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
7.6
22.6
53
71
TPH00
SPAT
NA
121.2
22.6
24
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
21.2
677
4711
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
20.2
20.4
30
15
D47.0
ICD-10 Finland
Histiocytic and mast cell tumours of uncertain and unknown behaviour
58.0
19.9
23
*
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
16.5
19.6
31
19
B75
ICPC
Neoplasm blood benign/unspecified
105.9
19.6
21
*
L01AB01
ATC
busulfan; systemic
201.6
19.6
20
*
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
18.3
19.1
29
16
20899
ICD-8 Finland
Polycythaemia vera
+∞
18.8
18
*
B01AA03
ATC
warfarin; systemic
1.6
18.0
521
3510
R04.0
ICD-10 Finland
Epistaxis
2.1
17.3
198
972
D73.5
ICD-10 Finland
Infarction of spleen
21.0
17.3
25
12
I81
ICD-10 Finland
Portal vein thrombosis
10.8
16.9
32
30
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
4.1
16.6
64
158
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
3.7
16.1
70
192
R50.9
ICD-10 Finland
Fever, unspecified
1.8
15.7
304
1814
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.0
15.4
195
1002
C03CA01
ATC
furosemide; systemic
1.5
15.3
711
5324
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
10.1
14.9
29
29
PH_2
NOMESCO Finland
Other procedures on veins
+∞
14.6
14
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
14.0
259
1522
2387X
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Other lymphatic and haematopoietic tissues[STATUS LYMPHO- ET MYELOPROLIFERATIVUS NUD]
+∞
13.6
13
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.1
13.4
152
746
D69.1
ICD-10 Finland
Qualitative platelet defects
40.3
13.2
16
*
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.0
13.1
166
852
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
8.1
12.8
28
35
2387B
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Other lymphatic and haematopoietic tissues[THROMBOCYTHAEMIA IDIOPATHICA]
+∞
12.5
12
*
S97
ICPC
Chronic ulcer skin
2.1
12.5
142
699
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
12.5
12.1
21
17
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.9
12.1
193
1081
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
12.0
441
3112
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
12.0
254
1555
B03XA01
ATC
erythropoietin; parenteral
5.1
12.0
37
74
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.8
11.4
217
1289
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.1
11.3
135
677
306
Kela drug reimbursment
Erythropoietin and darbepoetin
8.6
11.0
23
27
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
11.0
332
2235
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
6.0
10.9
29
49
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.1
10.9
127
631
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
15.5
10.8
17
11
D75
ICD-10 Finland
Other diseases of blood and blood-forming organs
60.3
10.6
12
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.7
10.6
225
1380
XW000
SPAT
NA
110.5
10.4
11
*
2387A
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Other lymphatic and haematopoietic tissues[MYELOFIBROSIS]
+∞
10.4
10
*
A05AA02
ATC
ursodeoxycholic acid; oral
4.2
10.3
38
92
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.6
10.3
249
1582
R71
ICD-10 Finland
Abnormality of red blood cells
13.2
10.2
17
13
K99
ICPC
Cardiovascular disease other
2.5
10.1
76
309
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.3
10.0
92
412
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
2.5
9.8
75
307
D47.7
ICD-10 Finland
Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
26.1
9.8
13
5
J01DB01
ATC
cefalexin; oral
1.4
9.8
1690
15412
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
9.8
239
1524
C07AB07
ATC
bisoprolol; oral
1.3
9.8
1052
8939
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
9.7
353
2474
J01MA12
ATC
levofloxacin; systemic
1.5
9.7
388
2779
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
1.8
9.7
154
860
127
Kela drug reimbursment
Transplant complication
3.9
9.5
37
95
D73.1
ICD-10 Finland
Hypersplenism
21.8
9.3
13
6
ZX120
NOMESCO Finland
Intravenous
1.7
9.1
196
1208
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
9.0
466
3502
D68.8
ICD-10 Finland
Other specified coagulation defects
4.4
9.0
31
71
B86
ICPC
OTHER HAEMATOLOGICAL ABNORMALITY
36.8
9.0
11
*
SPAT1088
SPAT
Blood transfusion
6.1
8.9
23
38
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
3.1
8.7
45
146
C90.0
ICD-10 Finland
Multiple myeloma
3.5
8.6
38
109
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
2.7
8.6
55
204
A02BC02
ATC
pantoprazole; systemic
1.3
8.4
1359
12112
B59
ICPC
Blood and Immunity, Other therap proced/minor surg NEC
+∞
8.3
8
*
C94.5
ICD-10 Finland
Acute myelofibrosis
+∞
8.3
8
*
M10.9
ICD-10 Finland
Gout, unspecified
1.8
8.2
149
872
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
3.8
8.1
32
84
D46.2
ICD-10 Finland
Refractory anaemia with excess of blasts [RAEB]
17.2
8.1
12
7
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
8.0
423
3186
D64.9
ICD-10 Finland
Anaemia, unspecified
1.6
8.0
219
1435
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.6
8.0
53
203
D46.0
ICD-10 Finland
Refractory anaemia without ring sideroblasts, so stated
15.1
7.7
12
8
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
3.1
7.6
40
132
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
18.4
7.6
11
6
JMA11
NOMESCO Finland
Laparoscopic total splenectomy
11.9
7.6
13
11
D58.2
ICD-10 Finland
Other haemoglobinopathies
25.1
7.6
10
*
D47
ICD-10 Finland
Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
80.3
7.4
8
*
WW200
NOMESCO Finland
Immunization
2.4
7.3
56
233
I67.6
ICD-10 Finland
Nonpyogenic thrombosis of intracranial venous system
10.9
7.3
13
12
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
7.1
500
3944
I82.0
ICD-10 Finland
Budd-Chiari syndrome
20.1
7.1
10
5
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.7
7.1
145
881
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.7
6.9
203
2874
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
2.0
6.9
85
437
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
1.8
6.9
103
569
T14.5
ICD-10 Finland
Injury of blood vessel(s) of unspecified body region
5.0
6.8
20
40
L04AX02
ATC
thalidomide; oral
16.7
6.7
10
6
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
2.4
6.7
52
218
C03DA01
ATC
spironolactone; oral
1.5
6.7
238
1657
K93
ICPC
Pulmonary embolism
3.4
6.7
30
89
AA1AD
NOMESCO Finland
CT of head and brain
1.3
6.7
504
4015
H02AB06
ATC
prednisolone; systemic
1.3
6.7
929
8027
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.3
6.6
59
264
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
6.6
218
1495
M10.4
ICD-10 Finland
Other secondary gout
12.3
6.6
11
9
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
10.0
6.5
12
12
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.6
6.5
164
1058
A46
ICD-10 Finland
Erysipelas
1.4
6.5
287
2088
R60.0
ICD-10 Finland
Localized oedema
1.5
6.4
227
1583
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
8.2
6.3
13
16
DKW00
NOMESCO Finland
Cauterisation of mucosa of nose
3.2
6.3
30
94
9989/3-C42.1
ICD-O-3
Myelodysplastic syndrome, NOS, of bone marrow
11.0
6.3
11
10
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
1.8
6.3
94
520
L03AB01
ATC
interferon alfa natural; parenteral
+∞
6.3
6
*
R51.80
ICD-10 Finland
Headache
1.5
6.2
232
1632
R89.8
ICD-10 Finland
Abnormal findings in specimens from other organs, systems and tissues, other abnormal findings
26.7
6.2
8
*
V03AC03
ATC
deferasirox; oral
26.7
6.2
8
*
UJF30
NOMESCO Finland
Ileoscopy through colon
1.5
6.2
180
1203
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
6.1
1274
11490
J96.1
ICD-10 Finland
Chronic respiratory failure
2.4
6.1
47
196
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.4
6.1
361
2771

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
2325
12047
5.96
307.65
16.4
5.7
0.2
0.2
e9/l
5.18
2162
10467
819
2004
5.32
307.65
10.3
3.8
1.3
0.8
%
3.87
378
590
1057
2210
7.00
307.65
3.9
2.5
79.2
69.1
e9/l
12.56
789
1695
2230
11007
5.65
307.65
15.5
5.7
61.4
57.8
%
35.83
2156
10223
1887
8103
4.90
307.65
15.5
5.5
—
—
—
0
0
2258
11184
5.83
307.65
17.2
5.9
24.4
27.0
%
24.09
2191
10344
620
253
31.01
307.65
1.3
1.2
—
—
—
0
0
477
209
27.19
307.65
1.1
1.2
—
—
—
0
0
2299
11654
5.95
307.65
15.0
5.5
0.1
0.0
e9/l
72.68
2123
9974
680
402
21.88
307.65
1.4
1.5
—
—
—
0
0
2250
10960
5.93
307.65
17.6
6.0
8.2
8.8
%
15.93
2185
10192
2294
11599
5.93
307.65
14.9
5.5
0.6
0.6
e9/l
1.61
2118
9915
1664
6349
4.87
307.65
4.6
2.7
1669.2
6135.5
umol/l
7.32
1545
5423
814
381
29.46
307.65
1.3
1.2
26.1
46.8
u/l
1.29
672
331
2250
10915
5.97
307.65
16.6
5.7
2.7
2.8
%
4.64
2184
10107
1261
2982
6.77
307.65
4.0
2.5
1.9
1.8
%
2.42
1119
2627
2231
10633
5.99
307.65
16.5
5.8
1.1
0.7
%
81.85
2161
9862
2305
11881
5.84
307.65
15.2
5.6
2.0
1.9
e9/l
0.20
2166
10346
756
1819
5.29
303.80
10.0
3.7
1.1
0.5
%
6.17
280
421
760
1910
5.06
288.82
10.1
3.9
0.2
0.1
%
2.18
361
548
1043
3375
4.29
285.80
2.8
2.6
22.4
22.3
%
0.12
919
2882
2370
13641
5.30
280.70
21.4
8.7
5.4
4.2
e9/l
23.94
2213
11838
1059
3609
4.07
267.41
2.6
2.5
2.4
2.3
g/l
10.70
1002
3335
703
1787
4.89
261.41
10.3
3.9
1.0
0.3
%
1.25
297
454
1097
3891
3.95
260.48
2.7
2.5
13.2
12.6
umol/l
1.47
1040
3601
1136
4830
3.24
192.75
12.6
4.4
—
—
—
0
0
2076
12728
3.30
179.99
9.8
6.2
12.3
11.8
umol/l
0.98
2019
12048
262
423
6.72
157.16
9.0
3.3
1.6
1.4
%
0.61
198
323
1663
9565
2.76
151.36
3.9
2.8
149.4
142.5
ug/l
0.22
1544
8720
1673
10296
2.50
122.46
21.1
9.8
0.1
0.0
e9/l
3.98
1491
8363
411
1227
3.74
117.26
1.8
1.8
1.1
1.5
g/l
18.96
352
1057
1156
6404
2.35
101.72
2.6
2.2
5.1
3.0
mg/l
22.90
989
5415
166
263
6.64
100.79
9.2
3.3
67.8
56.5
%
5.71
96
166
2407
18545
2.88
95.88
15.5
7.6
84.8
79.4
u/l
5.60
2342
17413
217
466
4.96
95.17
5.5
3.4
62.3
57.6
%
4.43
217
466
163
281
6.09
90.95
10.8
3.9
—
—
—
0
0
62
24
26.38
89.69
1.0
1.2
—
—
—
0
0
1812
12548
2.21
87.58
8.0
6.8
1.2
1.2
mmol/l
0.21
1523
10525
140
223
6.55
84.45
1.1
1.1
—
—
—
0
0
89
86
10.65
80.94
1.1
1.1
—
—
—
0
0
1217
7485
2.09
76.90
5.7
4.0
7.4
7.4
ph
3.76
248
1432
1019
6046
2.06
69.23
14.1
6.4
—
—
—
0
0
1625
11416
1.98
67.63
7.3
6.0
1.2
1.2
mmol/l
5.06
1490
10273
382
1547
2.70
62.98
5.2
3.2
5.5
4.1
e9/l
6.04
249
1165
206
599
3.63
59.96
3.4
2.8
1.4
1.6
mg/l
6.18
199
538
993
6122
1.95
58.33
1.8
1.6
20.3
20.5
nmol/l
0.18
878
5159
1488
10470
1.88
58.13
2.4
2.1
91.3
94.1
pmol/l
1.50
912
5323
88
130
6.95
56.90
1.9
1.6
—
—
—
0
0
1500
10854
1.80
50.89
6.1
4.7
35.5
35.0
g/l
2.54
1405
10061
64
77
8.48
49.35
1.5
1.6
—
—
—
0
0
960
6151
1.84
48.05
5.5
3.9
83.3
87.8
%
5.81
909
5996
517
2696
2.12
47.13
4.9
2.6
6.9
8.8
umol/l
1.69
466
2354
446
2195
2.22
47.08
2.9
2.7
66.7
66.3
g/l
0.55
405
1995
233
848
2.90
46.61
2.7
1.9
22.6
21.6
s
0.65
206
755
1841
14450
1.77
44.46
5.6
4.8
6.6
6.8
mmol/l
5.83
1773
13576
589
3322
1.97
42.87
4.8
5.6
1.1
1.0
mmol/l
1.92
549
3055
662
3888
1.91
42.71
2.7
2.0
32.1
29.9
s
11.32
624
3768
378
1852
2.20
39.96
2.8
2.5
—
—
—
0
0
801
5105
1.79
39.27
2.1
1.7
1.2
1.4
mg/l
1.10
622
3940
670
4075
1.84
38.19
3.7
3.2
0.8
0.8
mmol/l
1.43
635
3788
2103
17476
1.77
38.17
5.2
4.2
11.9
13.4
mm/h
3.97
1968
16082
778
5058
1.74
34.90
1.9
1.8
1089.5
1176.0
nmol/l
1.89
587
3777
344
1709
2.15
34.89
2.9
2.8
10.4
10.6
g/l
0.40
312
1554
204
844
2.53
31.55
3.5
3.5
1.6
1.7
ratio
0.03
22
67
208
872
2.49
31.28
3.5
3.5
55.3
125.5
mg/l
0.53
184
708
208
872
2.49
31.28
3.5
3.5
37.4
71.2
mg/l
1.29
185
708
282
1350
2.21
31.27
2.0
1.8
1.6
1.4
g/l
0.52
254
1227
228
1039
2.30
28.41
3.0
2.5
3.5
3.8
g/l
2.44
160
752
214
969
2.31
27.05
2.9
2.5
11.3
10.3
g/l
1.71
174
825
1339
10469
1.52
26.15
13.4
10.2
1.4
1.3
inr
2.04
432
2926
29
6
48.78
24.28
1.9
3.3
—
—
—
0
0
181
819
2.29
22.88
3.0
2.3
38.6
37.6
g/l
1.29
155
707
36
57
6.38
21.82
1.0
1.0
—
—
—
0
0
358
2110
1.80
21.57
3.2
3.9
1.2
1.2
mmol/l
1.64
307
1829
153
662
2.39
21.44
3.6
3.6
—
—
—
0
0
35
55
6.43
21.37
1.6
1.1
—
—
—
0
0
1032
7943
1.47
20.11
3.3
3.1
2254.5
1577.0
ng/l
2.09
897
6848
135
573
2.42
19.75
1.7
1.6
—
—
—
0
0
449
2885
1.66
19.71
1.3
1.3
406.2
534.5
titre
1.06
90
630
2509
23058
1.72
19.66
26.8
15.8
20.2
25.5
mg/l
15.71
2172
18573
938
7171
1.46
18.57
5.8
4.4
—
—
—
0
0
29
45
6.50
17.92
3.8
1.5
—
—
—
0
0
22
7
31.65
17.02
1.0
1.0
—
—
—
0
0
22
7
31.65
17.02
1.0
1.0
—
—
—
0
0
22
7
31.65
17.02
1.0
1.0
—
—
—
0
0
22
7
31.65
17.02
1.0
1.0
—
—
—
0
0
22
7
31.65
17.02
1.0
1.0
—
—
—
0
0
18
17
10.65
16.44
1.3
1.4
—
—
—
0
0
575
4070
1.52
16.41
1.5
1.5
2.4
2.6
g/l
0.99
357
2415
363
2310
1.65
16.37
5.7
7.1
9.7
10.4
mmol/l
1.03
341
2188
57
168
3.44
16.31
2.3
2.0
29.1
44.6
%
—
8
21
24
35
6.91
15.70
1.5
1.4
—
—
—
0
0
90
353
2.60
15.60
1.3
1.4
162.3
119.9
u/ml
0.28
13
69
2366
21722
1.52
15.37
5.1
4.1
1.3
1.3
mmol/l
0.40
2224
19522
346
2217
1.64
15.14
1.4
1.4
—
—
—
0
0
116
519
2.29
15.11
1.2
1.2
—
—
—
0
0
334
2124
1.65
15.05
1.4
1.5
—
—
—
0
0
233
1342
1.80
15.02
1.3
1.4
—
—
—
0
0
2080
18673
1.42
14.83
37.7
19.1
15.7
13.8
%
158.85
2064
18218
975
7763
1.39
14.51
5.1
2.4
—
—
—
0
0
316
2001
1.65
14.46
4.4
4.1
—
—
—
0
0
151
763
2.03
14.45
3.8
3.5
—
—
—
0
0
363
2404
1.58
13.81
1.4
1.5
—
—
—
0
0
86
354
2.47
13.52
1.2
1.2
303.3
265.0
u/ml
0.48
55
207
413
2829
1.54
13.52
2.1
1.8
—
—
—
0
0
74
291
2.58
12.81
1.1
1.2
4.5
5.4
u/ml
0.16
37
125
660
5012
1.41
12.67
3.1
2.8
541.0
544.5
mosm/kgh2o
0.16
581
4280
58
202
2.91
12.66
3.7
2.1
0.8
1.1
e9/l
1.32
29
119
92
404
2.32
12.56
1.3
1.3
—
—
—
0
0
773
6060
1.38
12.21
3.8
3.6
—
—
—
0
0
1041
8570
1.34
11.90
3.2
3.4
2.3
2.4
mmol/l
2.59
898
7376
73
296
2.50
11.89
1.1
1.2
—
—
—
0
0
55
194
2.87
11.75
2.6
2.4
—
—
—
0
0
79
335
2.40
11.69
1.1
1.1
—
—
—
0
0
53
185
2.90
11.55
1.3
1.2
—
—
—
0
0
119
600
2.03
11.51
1.2
1.2
110.9
84.8
titre
0.33
11
42
190
1118
1.75
11.39
2.1
1.9
1.4
2.3
ug/l
0.92
168
976
43
134
3.24
11.36
4.1
2.1
1476.4
561.5
e6/l
0.49
34
113
1632
14376
1.31
11.32
3.8
3.2
61.1
52.9
u/l
2.83
1544
13199
316
2119
1.55
11.31
2.1
2.2
402.0
372.6
nmol/l
1.48
292
1921
837
6724
1.35
11.12
3.5
3.2
—
—
—
0
0
47
157
3.03
11.07
2.2
2.0
71.4
71.8
%
0.05
42
146
41
127
3.26
10.95
4.4
2.1
0.2
0.2
e9/l
0.28
35
113
929
7593
1.33
10.94
3.6
3.3
61.3
80.6
e6/l
0.38
726
5907
68
280
2.46
10.75
2.4
2.0
—
—
—
0
0
1828
16416
1.31
10.72
4.8
4.6
—
—
—
0
0
1334
11497
1.30
10.58
5.3
5.2
0.0
0.0
estimate
0.50
362
2172
45
152
2.99
10.42
2.3
2.1
16.3
13.7
%
0.34
15
56
2549
24156
1.51
10.40
28.1
18.5
139.4
139.6
mmol/l
4.03
2509
23531
1331
11485
1.30
10.39
3.9
3.9
0.0
0.0
estimate
0.00
372
2148
44
147
3.02
10.38
3.8
2.0
2791.7
707.4
e6/l
0.44
21
64
1304
11226
1.30
10.34
7.8
4.1
—
—
—
0
0
119
624
1.95
10.33
1.5
1.5
0.2
0.2
g/l
1.37
108
594
748
5972
1.34
10.20
5.0
2.3
—
—
—
0
0
1344
11640
1.29
10.09
3.9
3.9
0.0
0.0
estimate
1.08
364
2109
78
352
2.25
10.06
1.1
1.0
—
—
—
0
0
853
6958
1.32
9.99
3.6
3.2
0.5
0.5
e6/l
0.11
654
5325
622
4842
1.36
9.98
3.4
3.1
2.4
2.5
mmol/l
2.38
537
4254
2551
24213
1.49
9.97
29.7
18.7
4.0
4.0
mmol/l
7.63
2507
23552
121
647
1.91
9.92
1.4
1.5
1.1
1.2
g/l
1.42
111
615
16
25
6.43
9.81
1.1
1.0
—
—
—
0
0
471
3520
1.40
9.65
2.1
2.1
—
—
—
0
0
249
1647
1.56
9.45
3.9
3.6
5.2
5.2
kpa
0.10
221
1511
365
2616
1.45
9.42
5.1
4.4
—
—
—
0
0
153
898
1.74
9.29
2.3
2.2
271.4
744.4
ug/l
1.30
146
847
2265
21125
1.35
9.25
5.4
4.9
2.1
2.0
mu/l
0.12
2114
19073
928
7722
1.30
9.25
2.1
2.2
136.7
224.8
u/l
4.32
866
7211
244
1625
1.55
8.99
4.0
3.6
7.4
7.4
ph
0.14
29
200
337
2401
1.46
8.96
2.1
2.1
0.2
0.2
g/l
0.58
302
2235
2385
22451
1.37
8.95
5.6
4.6
1.3
1.5
mmol/l
55.51
2249
20361
38
128
3.00
8.88
1.6
2.8
30.8
39.1
%
0.84
11
47
1148
9855
1.28
8.85
2.5
2.2
78.5
78.9
nmol/l
0.18
1016
8669
34
108
3.17
8.77
1.6
2.5
1576.9
1273.1
u/ml
0.20
34
108
2401
22644
1.38
8.75
5.6
4.6
4.2
4.6
mmol/l
77.79
2280
20684
206
1330
1.59
8.69
2.9
3.2
4.4
4.4
pmol/l
0.51
167
1156
25
65
3.87
8.68
1.2
1.1
—
—
—
0
0
1132
9721
1.27
8.64
4.3
3.9
47.9
102.7
ng/l
0.64
886
7152
667
5353
1.32
8.56
2.9
2.6
4.8
5.4
e6/l
0.64
599
4712
910
7618
1.29
8.50
2.8
2.6
53.2
58.1
u/l
3.86
829
7004
382
2812
1.41
8.49
1.5
1.6
—
—
—
0
0
1914
17528
1.28
8.42
4.3
4.0
15.1
15.0
pmol/l
1.63
1745
15726
226
1512
1.54
8.16
6.2
7.0
24.7
25.0
mmol/l
0.39
226
1505
170
1064
1.64
8.15
1.2
1.2
—
—
—
0
0
1025
8744
1.27
8.13
4.2
3.8
117.3
118.4
e6/l
0.01
763
6335
92
481
1.94
8.13
1.2
1.3
57.6
61.8
mmol/l
0.52
74
382
27
79
3.44
7.94
1.3
1.2
—
—
—
0
0
106
596
1.81
7.51
1.9
2.0
16.1
12.1
mg/l
1.03
91
546
368
2759
1.38
7.31
1.8
1.4
—
—
—
0
0
2553
24463
1.41
7.24
22.9
10.9
25.2
25.7
u/l
0.96
2500
23499
2435
23173
1.34
7.09
6.1
5.2
2.4
2.7
mmol/l
53.30
2307
21052
46
195
2.38
6.95
2.1
2.3
—
—
—
0
0
98
552
1.80
6.93
2.6
2.5
16.4
16.0
%
0.28
48
278
104
597
1.77
6.90
4.8
4.8
8.2
8.4
kpa
0.72
104
590
131
807
1.65
6.74
1.2
1.2
0.2
0.8
u/ml
—
7
67
433
3383
1.33
6.56
1.3
1.2
—
—
—
0
0
102
593
1.75
6.50
4.7
4.7
2.6
2.8
mmol/l
0.17
71
414
102
594
1.74
6.46
4.8
4.7
5.0
5.1
kpa
0.12
102
588
27
91
2.99
6.38
2.6
2.0
—
—
—
0
0
33
128
2.60
6.04
2.0
1.5
—
—
—
0
0
742
6286
1.24
5.87
4.3
4.3
0.0
0.0
estimate
0.88
356
2082
449
3580
1.30
5.86
32.9
26.9
1.5
1.4
inr
1.11
71
503
28
102
2.76
5.79
35.0
26.7
118.4
115.6
ug/l
0.10
28
85
86
494
1.76
5.75
3.0
2.8
—
—
—
0
0
2156
20352
1.24
5.69
32.5
16.9
39.2
39.1
%
0.15
1364
13522
98
586
1.70
5.69
3.7
3.8
—
—
—
0
0
297
2240
1.36
5.68
2.3
2.4
32.9
39.1
u/l
1.40
257
1922
18
51
3.55
5.60
1.1
1.1
—
—
—
0
0
2280
21681
1.25
5.49
6.4
6.2
38.4
40.5
mmol/mol
23.18
2146
19836
600
5002
1.25
5.43
3.9
3.9
648.9
566.8
ng/l
0.07
485
4108
902
7854
1.22
5.41
3.3
3.4
—
—
—
0
0
96
580
1.68
5.38
3.1
2.9
7.6
7.9
kpa
0.92
91
527
37
161
2.32
5.35
1.9
1.4
1440.3
1812.2
ml
—
6
34
283
2144
1.36
5.26
6.7
7.8
—
—
—
0
0
316
2435
1.33
5.25
3.4
3.4
5.7
5.8
kpa
0.90
307
2362
51
959
0.52
5.14
1.6
1.5
—
—
—
0
0
170
1187
1.46
5.07
4.4
3.7
—
—
—
0
0
64
350
1.85
5.07
1.1
1.1
—
—
—
0
0
1716
15933
1.19
4.94
5.1
4.8
3244.4
2105.6
e6/l
0.16
20
251
313
2433
1.32
4.90
3.5
3.4
1.5
2.0
mmol/l
1.20
256
1946
57
304
1.89
4.89
1.3
1.4
75.7
51.5
mu/l
0.26
47
270
296
2285
1.33
4.87
5.8
6.6
1.5
1.4
mmol/l
0.52
288
2204
38
175
2.19
4.84
1.1
1.2
140.0
120.3
titre
—
5
32
146
1000
1.48
4.82
4.4
3.9
24.5
24.9
mmol/l
1.01
129
917
109
705
1.57
4.69
4.6
4.4
7.4
7.4
ph
0.23
102
587
52
273
1.92
4.69
1.8
1.5
—
—
—
0
0
52
273
1.92
4.69
1.8
1.5
—
—
—
0
0
52
273
1.92
4.69
1.8
1.5
—
—
—
0
0
52
273
1.92
4.69
1.8
1.5
—
—
—
0
0
262
1998
1.34
4.68
3.3
3.7
87.7
93.9
ng/l
0.57
223
1698
106
682
1.58
4.67
3.2
3.2
25.3
25.1
mmol/l
0.20
98
586
376
3018
1.28
4.64
6.9
7.0
11.9
12.0
kpa
0.16
361
2869
376
3018
1.28
4.64
6.9
7.1
5.0
5.1
kpa
1.47
362
2868
233
1754
1.36
4.54
5.1
4.7
—
—
—
0
0
339
2696
1.29
4.49
7.2
7.4
94.9
95.5
%
0.76
329
2590
19
65
2.94
4.44
1.5
1.4
—
—
—
0
0
2355
22617
1.23
4.35
5.2
4.9
6.0
6.0
mmol/l
1.42
2147
20358
16
50
3.21
4.33
1.5
1.4
—
127.3
titre
—
0
9
16
50
3.21
4.33
1.1
1.1
—
—
—
0
0
14
40
3.51
4.33
1.4
1.8
67.1
202.7
e6/l
—
7
15
21
78
2.70
4.25
2.3
2.0
—
—
—
0
0
371
3013
1.27
4.16
7.0
7.0
1.1
1.1
mmol/l
0.05
291
2354
65
386
1.70
3.98
1.1
1.3
—
—
—
0
0
15
48
3.14
3.93
1.1
1.1
—
—
—
0
0
187
1401
1.36
3.80
7.6
9.0
24.5
24.4
mmol/l
0.04
181
1308
396
3275
1.24
3.79
7.0
6.6
104.0
104.2
mmol/l
0.45
389
3193
14
44
3.19
3.77
1.1
1.1
—
—
—
0
0
476
4017
1.22
3.77
3.3
3.0
1.7
2.4
e6/l
1.57
244
2219
325
2639
1.26
3.66
1.2
1.3
—
—
—
0
0
51
291
1.77
3.62
1.2
1.5
—
—
—
0
0
1783
16814
1.16
3.60
4.5
4.1
—
—
—
0
0
841
7504
1.17
3.56
4.6
4.2
—
—
—
0
0
1055
9586
1.16
3.52
2.3
2.2
—
—
—
0
0
71
447
1.60
3.51
2.3
3.1
—
—
—
0
0
33
167
1.99
3.39
1.5
1.2
—
—
—
0
0
52
305
1.72
3.38
1.3
1.2
—
—
—
0
0
49
283
1.74
3.36
1.1
1.3
301.8
290.8
pmol/l
0.09
38
221
31
154
2.02
3.35
4.5
3.5
—
—
—
0
0
162
1213
1.36
3.33
3.8
3.6
23.9
24.2
mmol/l
0.43
154
1082
34
175
1.95
3.33
1.4
2.6
—
—
—
0
0
17
65
2.63
3.30
1.1
1.1
—
—
—
0
0
161
1214
1.35
3.18
1.4
1.3
—
—
—
0
0
81
541
1.51
3.13
2.4
2.9
38.5
37.2
umol/l
0.10
64
452
211
1658
1.29
3.12
1.2
1.2
—
—
—
0
0
144
1073
1.36
3.08
4.4
5.3
2.0
1.6
%
1.47
133
1003
51
306
1.68
3.08
1.2
1.4
130781.3
85344.3
e6/l
0.29
32
182
83
561
1.49
3.04
1.2
1.2
1.8
4.0
u/ml
—
5
54
9
21
4.30
2.99
1.0
1.0
—
—
—
0
0
29
148
1.97
2.94
2.7
3.0
—
—
—
0
0
529
4615
1.18
2.90
1.3
1.2
2.2
1.4
u/ml
0.43
100
1173
45
266
1.70
2.89
1.4
1.2
—
—
—
0
0
52
320
1.64
2.87
1.8
1.6
0.8
0.8
g/l
0.01
39
240
58
368
1.59
2.84
2.5
2.6
—
—
—
0
0
35
193
1.82
2.84
1.6
1.8
—
—
—
0
0
493
4290
1.18
2.79
3.1
2.8
0.8
1.2
e6/l
1.77
260
2479
16
65
2.47
2.79
1.4
1.4
—
—
—
0
0
59
378
1.57
2.78
1.2
1.5
30.9
32.0
g/l
0.30
52
343
19
84
2.27
2.77
2.2
2.0
1335.8
23742.2
e6/l
0.54
13
49
245
2004
1.24
2.64
3.0
2.9
4.5
4.5
kpa
0.00
239
1938
26
134
1.95
2.60
1.2
1.3
—
—
—
0
0
296
2475
1.22
2.59
2.2
2.2
184.6
157.9
ug/g
0.36
237
1925
15
62
2.43
2.54
1.1
1.0
—
—
—
0
0
19
88
2.17
2.51
1.4
1.3
—
—
—
0
0
295
2475
1.21
2.50
7.9
7.8
119.4
121.0
g/l
0.54
285
2383
15
63
2.39
2.46
2.4
2.0
—
—
—
0
0
53
344
1.55
2.40
1.2
1.4
1913.0
1805.0
e6/l
0.07
37
250
44
275
1.61
2.34
1.3
1.3
272.4
276.9
mosm/kgh2o
0.65
37
206
279
2353
1.21
2.26
3.3
3.0
229.1
220.8
ng/l
0.12
256
2142
411
3589
1.17
2.24
1.2
1.2
11.5
13.4
u/ml
0.23
139
1336
45
287
1.58
2.22
1.1
1.2
—
—
—
0
0
5
9
5.56
2.21
2.6
1.3
—
—
—
0
0
428
3756
1.16
2.19
1.3
1.3
27.8
38.2
iu/ml
1.14
137
1181
8
24
3.34
2.18
2.1
1.1
—
—
—
0
0
8
24
3.34
2.18
2.1
1.1
—
—
—
0
0
8
24
3.34
2.18
2.1
1.1
—
—
—
0
0
2576
25272
1.19
2.15
46.8
23.1
401.5
245.4
e9/l
316.86
2535
24559
45
290
1.56
2.14
1.2
1.2
—
—
nmol/l
—
0
0
24
130
1.85
2.12
1.3
1.3
1.4
1.2
nmol/l
0.36
15
101
135
1059
1.29
2.11
4.7
5.4
0.9
0.9
%
0.57
124
990
2576
25278
1.19
2.11
46.5
23.1
94.0
91.4
fl
25.70
2552
24842
2576
25279
1.19
2.10
46.4
23.0
30.6
30.4
pg
2.24
2552
24840
19
95
2.01
2.10
2.2
2.2
560.4
776.9
e6/l
0.42
13
74
2576
25281
1.19
2.09
46.7
23.1
4.4
4.4
e12/l
0.26
2525
24480
2576
25286
1.19
2.06
46.8
23.2
9.0
6.8
e9/l
33.52
2527
24481
28
161
1.75
2.05
1.1
1.1
—
—
—
0
0
2576
25287
1.19
2.05
47.0
23.3
131.7
134.1
g/l
9.37
2552
24856
52
350
1.49
2.04
2.4
2.5
—
—
—
0
0
15
69
2.18
2.04
1.1
1.3
—
—
—
0
0
2428
23730
1.15
2.02
24.7
15.0
—
—
—
0
0
24
133
1.81
1.99
1.0
1.1
—
—
—
0
0
5
11
4.55
1.94
1.0
1.0
46.1
35.4
s
—
5
11
19
99
1.93
1.90
1.3
1.2
—
—
—
0
0
22
121
1.82
1.88
1.5
2.5
—
—
—
0
0
31
189
1.65
1.87
1.3
1.1
—
—
—
0
0
36
551
0.65
1.84
1.2
1.2
—
—
—
0
0
6
17
3.53
1.83
1.0
1.0
—
—
—
0
0
6
17
3.53
1.83
1.0
1.0
—
—
—
0
0
6
17
3.53
1.83
1.0
1.0
—
—
—
0
0
32
199
1.61
1.80
1.1
1.4
—
—
—
0
0
38
247
1.55
1.78
1.0
1.1
—
—
—
0
0
159
1302
1.23
1.78
3.2
3.2
24.6
25.3
mmol/l
1.49
151
1260
44
297
1.49
1.75
1.3
1.6
—
—
—
0
0
107
1354
0.78
1.74
1.4
1.4
—
—
—
0
0
32
202
1.59
1.71
1.4
1.2
339.7
359.4
nmol/l
0.21
27
172
31
196
1.59
1.65
1.1
1.4
0.4
0.4
g/l
0.04
21
134
31
196
1.59
1.65
1.1
1.4
6.8
7.2
g/l
0.18
22
134
31
196
1.59
1.65
1.1
1.4
2.6
2.9
g/l
0.48
21
134
22
127
1.74
1.64
1.0
1.0
—
—
—
0
0
79
600
1.33
1.63
1.3
1.3
26.7
31.4
iu/l
0.76
72
510
26
158
1.65
1.62
2.6
1.6
—
—
—
0
0
58
420
1.39
1.61
1.4
1.3
12.9
10.3
u/l
0.89
51
335
682
6291
1.11
1.61
1.6
1.6
1.4
1.4
mmol/l
1.70
583
5208
75
568
1.33
1.58
2.3
2.2
131.6
128.0
g/l
0.40
60
411
18
99
1.82
1.57
2.1
2.6
—
—
—
0
0
11
50
2.20
1.57
1.4
1.6
—
—
—
0
0
47
331
1.43
1.54
2.5
2.5
—
—
—
0
0
8
33
2.43
1.53
1.1
1.2
—
—
—
0
0
38
257
1.49
1.53
1.8
2.9
—
—
—
0
0
89
695
1.29
1.52
1.2
1.2
—
—
—
0
0
7
27
2.60
1.51
1.0
1.1
—
—
—
0
0
6
21
2.86
1.50
1.7
2.7
—
—
—
0
0
24
148
1.63
1.44
1.5
1.5
1.0
1.0
g/l
0.03
24
148
166
1404
1.19
1.40
9.1
9.8
—
—
—
0
0
39
271
1.45
1.39
1.2
1.4
—
—
—
0
0
6
23
2.61
1.36
1.0
1.1
—
—
—
0
0
6
23
2.61
1.36
1.3
2.1
—
—
—
0
0
25
159
1.58
1.34
1.2
1.3
—
—
—
0
0
7
150
0.47
1.31
1.6
1.5
—
—
—
0
0
87
695
1.26
1.28
4.3
4.6
—
—
—
0
0
158
1343
1.19
1.28
3.7
3.6
—
—
—
0
0
6
135
0.44
1.27
1.0
1.1
—
—
—
0
0
16
92
1.74
1.25
1.4
1.5
4.8
3.1
%
0.22
16
76
22
139
1.59
1.23
1.5
2.3
—
—
—
0
0
8
37
2.17
1.21
1.0
1.0
—
—
—
0
0
7
145
0.48
1.19
1.6
1.4
—
—
—
0
0
7
145
0.48
1.19
1.6
1.4
—
—
—
0
0
48
358
1.35
1.18
1.3
1.4
—
—
—
0
0
349
3160
1.12
1.18
1.3
1.3
—
—
—
0
0
91
740
1.24
1.17
1.4
1.4
293.7
277.7
ug/g
0.36
56
433
39
282
1.39
1.16
7.6
7.0
7.7
7.7
mmol/l
0.01
32
239
594
5531
1.09
1.16
1.6
1.7
23362930.6
24956262.5
pmol/l
0.02
458
4528
188
1640
1.16
1.13
8.6
6.8
24.1
24.6
mmol/l
0.74
177
1522
13
73
1.78
1.10
2.6
1.9
—
—
—
0
0
38
277
1.38
1.09
4.7
3.4
—
—
—
0
0
1828
18749
0.93
1.08
41.7
20.6
325.7
331.8
g/l
55.87
1816
18584
158
1367
1.16
1.07
2.4
2.5
—
—
—
0
0
449
4852
0.91
1.05
2.8
3.1
0.8
0.8
ug/l
0.07
309
3337
79
642
1.24
1.05
3.5
3.2
0.8
0.8
nmol/l
0.30
59
500
13
75
1.74
1.02
1.0
1.3
64.1
466.2
ug/l
—
8
39
40
299
1.34
1.00
1.4
1.9
—
—
—
0
0
28
390
0.72
0.98
1.5
1.7
—
—
—
0
0
37
275
1.35
0.97
1.6
1.6
—
—
—
0
0
9
50
1.80
0.96
1.4
1.4
—
—
—
0
0
229
2054
1.12
0.95
1.5
1.5
—
—
—
0
0
46
357
1.29
0.91
1.4
2.0
—
—
—
0
0
144
1257
1.15
0.90
1.3
1.3
169.9
219.7
u/ml
0.51
136
1153
15
94
1.60
0.90
2.0
2.0
79.1
87.2
umol/l
—
9
55
182
1616
1.13
0.89
2.7
3.0
127.1
128.0
g/l
0.19
173
1573
21
143
1.47
0.89
3.1
2.7
7.4
7.4
ph
—
8
46
635
6000
1.07
0.88
1.5
1.3
—
—
—
0
0
6
30
2.00
0.87
1.2
1.1
—
—
—
0
0
6
30
2.00
0.87
1.5
1.2
29.8
34.7
nmol/l
—
6
24
66
540
1.23
0.86
1.8
1.8
41.7
42.1
nmol/l
0.05
61
511
122
1057
1.16
0.86
5.8
4.4
—
—
—
0
0
13
80
1.63
0.84
1.2
1.2
38.1
38.6
g/l
—
7
40
10
57
1.76
0.83
2.8
2.5
—
—
—
0
0
588
5555
1.07
0.82
3.5
3.8
—
—
—
0
0
149
1317
1.14
0.81
1.2
1.2
99.7
141.0
iu/ml
0.87
52
475
40
312
1.29
0.79
1.2
1.3
—
—
—
0
0
8
48
1.67
0.78
1.4
2.0
—
—
—
0
0
125
1094
1.15
0.78
1.5
1.5
—
—
—
0
0
110
954
1.16
0.78
2.4
3.2
461.6
4418.0
u/ml
0.75
94
814
55
448
1.23
0.77
1.5
1.5
—
—
—
0
0
22
157
1.40
0.76
2.0
1.6
—
—
—
0
0
6
34
1.77
0.76
1.0
1.2
2.6
1.9
umol/24h
—
6
34
478
5072
0.93
0.74
4.3
4.4
1.0
1.0
kg/l
0.47
72
764
5
24
2.09
0.74
1.0
1.1
—
—
—
0
0
15
100
1.50
0.72
1.1
1.2
—
—
—
0
0
5
25
2.00
0.72
1.8
1.3
—
717.9
—
0
8
14
207
0.67
0.72
1.0
1.0
—
—
—
0
0
95
821
1.16
0.72
1.6
1.6
—
—
—
0
0
45
554
0.81
0.70
1.4
1.3
—
—
—
0
0
169
1522
1.12
0.70
2.6
2.4
26.4
25.1
au/ml
—
9
65
22
160
1.38
0.70
1.1
1.3
—
—
—
0
0
259
2387
1.09
0.69
2.3
2.4
5.1
7.1
ug/l
2.03
200
2078
118
1041
1.14
0.69
2.4
2.7
—
—
—
0
0
18
127
1.42
0.68
6.9
6.3
—
—
—
0
0
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
22
162
1.36
0.66
1.1
1.1
—
—
—
0
0
8
127
0.63
0.64
2.6
4.0
—
—
—
0
0
25
190
1.32
0.62
4.8
4.7
51.2
43.3
u/ml
—
9
53
47
389
1.21
0.60
1.4
1.9
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
47
390
1.21
0.59
1.4
1.9
—
—
—
0
0
10
64
1.56
0.58
1.0
1.0
—
—
—
0
0
19
140
1.36
0.58
1.3
1.7
—
—
—
0
0
17
123
1.38
0.57
1.8
2.5
2131.2
1891.3
ml
0.37
17
104
47
392
1.20
0.57
1.4
1.9
—
—
—
0
0
27
211
1.28
0.57
2.3
2.2
671.1
622.2
ml
0.28
16
137
6
38
1.58
0.54
1.0
1.6
—
—
—
0
0
90
796
1.13
0.54
5.8
3.9
4.0
3.9
mmol/l
1.09
85
737
20
152
1.32
0.52
1.3
1.3
10.4
12.0
mmol/l
—
10
57
37
305
1.22
0.51
1.1
1.1
—
11.4
—
0
14
67
584
1.15
0.50
1.4
1.1
—
—
—
0
0
74
840
0.88
0.50
1.8
1.7
—
—
—
0
0
27
335
0.80
0.49
3.1
4.8
352.7
350.8
umol/l
0.02
21
290
10
67
1.49
0.49
1.0
1.2
—
—
—
0
0
68
775
0.87
0.49
19.0
10.4
—
—
—
0
0
66
577
1.15
0.48
6.9
7.3
105.1
105.2
mmol/l
0.04
58
512
66
577
1.15
0.48
6.9
7.3
12.0
11.2
mmol/l
1.07
58
512
99
890
1.12
0.48
2.9
3.0
0.3
0.3
g/l
0.27
42
326
198
2127
0.93
0.48
3.7
3.5
—
—
—
0
0
173
1600
1.09
0.47
2.8
2.2
12.7
12.8
nmol/l
0.04
154
1389
52
602
0.86
0.47
1.0
1.1
—
—
—
0
0
12
85
1.41
0.46
1.3
1.4
18.3
23.9
%
0.39
12
77
7
49
1.43
0.46
1.1
1.1
—
—
—
0
0
8
117
0.68
0.45
2.6
4.2
—
—
—
0
0
18
138
1.31
0.45
7.4
14.2
—
—
—
0
0
7
50
1.40
0.45
6.6
8.1
—
—
—
0
0
20
156
1.28
0.45
2.4
2.0
486.6
489.0
min
0.03
12
113
45
386
1.17
0.43
1.5
1.8
—
—
—
0
0
144
1332
1.09
0.41
1.2
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
2.0
—
—
—
0
0
29
242
1.20
0.38
1.1
1.4
—
—
—
0
0
9
68
1.32
0.37
3.4
2.0
—
—
—
0
0
184
1728
1.07
0.37
1.4
1.4
—
—
—
0
0
5
37
1.35
0.37
1.4
1.3
42.0
73.8
%
—
5
32
12
158
0.76
0.37
1.0
1.5
—
72.4
—
0
12
29
245
1.19
0.35
1.5
1.6
—
—
—
0
0
37
320
1.16
0.34
1.4
1.9
15413.8
2119.4
u/l
—
8
127
6
44
1.36
0.34
1.8
1.1
—
—
—
0
0
292
2792
1.05
0.33
2.9
4.0
11.8
19.0
ug/l
0.39
217
2303
14
110
1.27
0.31
1.2
1.2
—
—
—
0
0
17
208
0.82
0.31
1.1
1.7
12.1
11.2
%
0.33
17
208
30
259
1.16
0.29
1.4
1.1
—
—
—
0
0
30
259
1.16
0.29
1.4
1.1
—
—
—
0
0
26
223
1.17
0.28
1.2
1.5
20.8
28.8
%
0.61
13
138
18
149
1.21
0.27
1.7
1.8
4.8
11.4
umol/l
0.87
12
95
118
1107
1.07
0.27
2.1
1.9
—
—
—
0
0
52
470
1.11
0.27
1.1
1.4
—
—
—
0
0
56
509
1.10
0.27
1.3
1.4
1154.4
1469.2
e6/l
0.11
46
411
56
509
1.10
0.27
1.2
1.4
34.9
30.2
e6/l
0.07
43
389
171
1627
1.05
0.26
3.3
3.2
—
—
—
0
0
27
235
1.15
0.25
1.1
1.5
—
—
—
0
0
771
7859
0.97
0.25
3.0
3.2
7.1
7.2
mmol/l
0.46
636
6518
11
87
1.27
0.24
1.2
2.0
26.4
109.2
ug/l
0.44
11
77
48
437
1.10
0.23
1.2
1.2
197.8
219.3
miu/ml
0.12
16
174
33
294
1.12
0.23
1.5
1.2
—
—
—
0
0
18
153
1.18
0.22
1.9
1.3
0.4
1.4
u/ml
0.76
13
75
33
368
0.90
0.22
1.1
1.1
74.0
86.4
iu/ml
—
6
75
60
648
0.92
0.22
1.1
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
6.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
0.2
—
0
5
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.4
—
0
5
64
597
1.07
0.19
2.5
2.2
—
—
—
0
0
81
764
1.06
0.18
1.0
1.1
—
—
—
0
0
13
109
1.19
0.18
1.0
1.0
—
—
—
0
0
7
58
1.21
0.18
1.0
1.1
—
—
—
0
0
7
58
1.21
0.18
1.0
1.1
—
—
—
0
0
7
58
1.21
0.18
1.0
1.1
—
—
—
0
0
7
59
1.19
0.18
1.7
1.3
—
—
—
0
0
33
302
1.09
0.16
1.3
1.5
70.5
62.0
%
0.60
18
191
794
8044
0.98
0.16
3.8
4.0
13.2
8.5
mg/mmol
1.25
477
5045
8
72
1.11
0.16
3.0
2.1
—
—
—
0
0
7
88
0.79
0.14
2.1
2.4
—
—
—
0
0
15
131
1.15
0.14
1.7
1.4
44.5
70.4
pmol/l
—
9
44
60
567
1.06
0.14
2.1
3.3
52.6
812.6
u/ml
1.01
50
522
50
531
0.94
0.13
1.3
1.9
2.7
4.7
iu/l
2.06
17
179
85
813
1.05
0.13
6.7
6.3
1.5
1.3
mmol/l
0.43
75
709
21
232
0.90
0.13
1.1
1.0
0.6
3.9
u/ml
3.57
13
105
851
8422
1.01
0.13
4.5
5.2
2.4
3.6
ug/l
1.47
746
7488
38
406
0.94
0.12
1.5
1.4
—
—
—
0
0
734
7262
1.01
0.12
3.9
3.1
—
—
—
0
0
16
178
0.90
0.11
1.1
1.0
1.9
2.3
u/ml
—
7
62
755
7626
0.99
0.11
3.2
3.3
1334.1
297.8
mg/l
2.62
460
4819
24
221
1.09
0.11
2.0
2.1
3.5
2.1
u/field
0.47
12
82
146
1499
0.97
0.10
1.2
1.2
—
—
—
0
0
22
203
1.08
0.09
1.0
1.0
5.1
1.8
u/ml
—
5
46
18
196
0.92
0.09
1.5
1.5
0.2
0.3
nmol/l
0.24
12
150
6
56
1.07
0.08
1.0
1.1
—
0.7
u/ml
—
0
6
5
62
0.81
0.08
1.2
1.5
—
—
—
0
0
18
166
1.08
0.07
1.3
1.4
1.3
1.1
promille
0.17
11
127
15
137
1.10
0.07
1.1
1.1
—
—
—
0
0
8
77
1.04
0.07
1.0
1.5
—
—
—
0
0
7
84
0.83
0.07
1.3
1.6
—
—
—
0
0
58
561
1.03
0.06
4.4
3.7
30.3
27.1
mg/l
0.26
35
353
9
104
0.86
0.06
1.2
1.3
12.7
23.3
umol/l
—
9
99
59
607
0.97
0.05
1.6
1.6
12033.5
14296.0
e6/l
0.26
44
429
15
161
0.93
0.05
1.1
1.0
3.7
2.9
u/ml
—
7
60
24
252
0.95
0.05
1.2
1.2
—
—
—
0
0
19
179
1.06
0.05
1.1
1.2
—
—
—
0
0
227
2291
0.99
0.04
1.6
1.6
—
—
—
0
0
10
92
1.09
0.03
1.2
1.4
3.2
3.2
mmol/l
—
10
82
30
291
1.03
0.02
3.3
2.6
—
—
—
0
0
18
172
1.05
0.02
1.9
2.5
—
—
—
0
0
42
411
1.02
0.02
1.2
1.4
—
—
—
0
0
23
238
0.97
0.02
1.3
1.2
—
—
—
0
0
20
207
0.97
0.01
1.2
1.4
24.0
29.3
u/l
0.43
14
168
49
497
0.99
0.01
1.3
1.8
0.8
0.8
nmol/l
0.01
41
408
10
94
1.06
0.01
3.0
2.4
—
—
—
0
0
11
116
0.95
0.00
1.2
1.4
—
1.4
—
0
7
11
115
0.96
0.00
2.3
1.2
218.5
136.7
nmol/l
1.62
11
115
17
165
1.03
0.00
1.8
2.1
2.2
2.0
ug/l
0.16
17
143
26
265
0.98
0.00
1.1
1.1
0.1
1.7
u/ml
—
9
108
17
169
1.01
0.00
1.9
2.0
4.1
3.2
ug/l
0.24
17
150
64
635
1.01
0.00
2.7
2.3
163.7
102.0
ug/min
0.36
36
386
10
104
0.96
0.00
1.0
1.1
—
—
—
0
0
23
226
1.02
0.00
1.0
1.0
0.1
1.3
u/ml
—
9
90
56
556
1.01
0.00
1.7
2.6
—
—
—
0
0
17
173
0.98
0.00
1.1
1.4
—
—
—
0
0
5
51
0.98
0.00
1.2
1.2
—
—
—
0
0
5
55
0.91
0.00
1.8
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
0.00
1.2
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
2.4
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
2984.0
—
0
5
8
86
0.93
0.00
1.1
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
211.2
—
0
5
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
1270.0
—
0
5
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
5
49
1.02
0.00
10.4
2.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
0.00
4.6
4.7
—
—
—
0
0
0
9
0.00
0.00
0.0
5.9
—
13.5
—
0
9
7
74
0.95
0.00
1.6
1.3
26.9
25.2
%
—
7
59
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
0.00
1.0
1.1
2113.7
1618.1
miu/ml
—
6
68
27
270
1.00
0.00
2.2
2.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: MYELOPROF_NONCML – Myeloproliferative diseases (CML excluded)

GWS hits: 22

This endpoint is excluded (different definition than used in FinnGen).