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Myeloproliferative diseases

MYELOPROF

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D75.2

1 out of 7 registries used, show all original rules.

907

4. Check minimum number of events

None

907

5. Include endpoints

3178

6. Filter based on genotype QC (FinnGen only)

3178

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 3178 1659 1519
Unadjusted period prevalence (%) 0.62 0.57 0.67
Median age at first event (years) 63.29 61.79 64.93

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2604
Matched controls
26041
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
+∞
323.0
1154
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
122.4
323.0
1779
450
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
+∞
323.0
397
*
9962/3-C42.1
ICD-O-3
Essential thrombocythemia of bone marrow
+∞
323.0
361
*
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
+∞
323.0
305
*
D75.2
ICD-10 Finland
Essential thrombocytosis
564.7
323.0
612
14
D45
ICD-10 Finland
Polycythaemia vera
4145.4
323.0
1092
5
L01XX05
ATC
hydroxycarbamide; oral
2279.4
323.0
1392
13
9950/3-C42.1
ICD-O-3
Polycythemia vera of bone marrow
+∞
323.0
310
*
XW000
NOMESCO Finland
Bone marrow biopsy
28.0
323.0
880
466
TPH00
NOMESCO Finland
Phlebotomy
419.5
323.0
365
10
SPAT1074
SPAT
Venesection
164.4
255.1
266
18
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
34.8
228.5
300
97
L03AB05
ATC
interferon alfa-2b; parenteral
136.3
200.6
213
17
L01XX35
ATC
anagrelide; oral
1941.7
199.5
191
*
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
68.4
185.8
214
34
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
947.4
182.6
177
*
189
Kela drug reimbursment
Imatinib
214.6
175.4
180
9
L01XE01
ATC
[U] imatinib; oral
184.2
150.4
156
9
M04AA01
ATC
allopurinol; systemic
3.8
139.6
708
2326
9960/3-C42.1
ICD-O-3
Myeloproliferative neoplasm, NOS, of bone marrow
+∞
136.7
130
*
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
+∞
131.4
125
*
B99
ICPC
Blood/lymph/spleen disease other
98.5
119.2
131
14
L03AB04
ATC
interferon alfa-2a; parenteral
162.6
118.3
124
8
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
107.7
591
2014
174
Kela drug reimbursment
Ruxolitinib
+∞
101.7
97
*
L01EA01
ATC
imatinib; oral (bcr-abl tyrosine kinase inhibitors)
316.7
90.4
91
*
374
Kela drug reimbursment
Ruxolitinib
+∞
88.0
84
*
316
Kela drug reimbursment
Imatinib
279.5
80.0
81
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.7
78.7
381
1149
D75.1
ICD-10 Finland
Secondary polycythaemia
32.4
77.7
103
33
212
Kela drug reimbursment
Gout
8.3
76.8
177
226
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
25.0
76.0
108
45
L01XE18
ATC
[U] ruxolitinib; oral
+∞
74.3
71
*
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
15.3
69.0
116
79
L01EJ01
ATC
ruxolitinib; oral
+∞
68.0
65
*
152
Kela drug reimbursment
Nilotinib
+∞
63.8
61
*
WW500
NOMESCO Finland
Blood transfusion
4.6
55.6
206
480
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
32.6
55.4
73
23
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
29.2
54.7
74
26
150
Kela drug reimbursment
Dasatinib
486.6
48.5
48
*
L01XX28
ATC
[D] imatinib; oral
+∞
47.0
45
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
45.4
1255
8828
L01XE06
ATC
[U] dasatinib; systemic
434.6
43.3
43
*
XX7BT
NOMESCO Finland
Radioactive phosphorus therapy
+∞
42.8
41
*
L01XE08
ATC
[U] nilotinib; oral
+∞
42.8
41
*
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
14.6
41.8
71
50
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
16.5
40.9
66
41
D75.0
ICD-10 Finland
Familial erythrocytosis
53.1
39.6
47
9
B03XA02
ATC
darbepoetin alfa; parenteral
6.1
39.3
110
186
B28
ICPC
Limited function/disability (B)
20.1
37.9
57
29
L03AA04
ATC
NA
26.2
35.4
49
19
B74
ICPC
Malignant neoplasm blood other
35.2
35.0
45
13
328
Kela drug reimbursment
Nilotinib
+∞
33.4
32
*
B04
ICPC
Blood symptom/complaint
18.5
33.1
51
28
L01EA03
ATC
nilotinib; oral
+∞
32.4
31
*
127
Kela drug reimbursment
Transplant complication
7.0
32.2
81
119
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
6.0
31.2
88
151
R50.9
ICD-10 Finland
Fever, unspecified
2.1
31.1
390
2006
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
7.4
29.5
71
98
B01AC14
ATC
[U] anagrelide; oral
+∞
29.2
28
*
D75.8
ICD-10 Finland
Other specified diseases of blood and blood-forming organs
64.7
28.0
32
5
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
15.8
27.7
45
29
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
13.2
27.4
48
37
324
Kela drug reimbursment
Dasatinib
+∞
27.1
26
*
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
50.5
25.3
30
6
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
12.0
25.2
46
39
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
25.1
765
5270
TPH00
SPAT
NA
+∞
25.0
24
*
2384A
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Polycythaemia vera
+∞
25.0
24
*
B01AB05
ATC
enoxaparin; parenteral
1.6
24.8
828
5837
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
29.4
24.1
32
11
A05AA02
ATC
ursodeoxycholic acid; oral
5.8
24.0
69
122
L01AB01
ATC
busulfan; systemic
+∞
24.0
23
*
C03CA01
ATC
furosemide; systemic
1.6
22.2
831
5995
D47.0
ICD-10 Finland
Histiocytic and mast cell tumours of uncertain and unknown behaviour
80.8
21.7
24
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
21.2
321
1763
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
11.0
21.1
40
37
B03XA01
ATC
erythropoietin; parenteral
7.1
20.9
51
73
C92.9
ICD-10 Finland
Myeloid leukaemia, unspecified
211.6
20.6
21
*
L01EA02
ATC
dasatinib; oral
211.6
20.6
21
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.1
19.9
228
1120
B75
ICPC
Neoplasm blood benign/unspecified
105.8
19.6
21
*
20899
ICD-8 Finland
Polycythaemia vera
+∞
18.8
18
*
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
4.0
18.5
75
193
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
30.3
18.3
24
8
R04.0
ICD-10 Finland
Epistaxis
2.1
18.3
215
1069
306
Kela drug reimbursment
Erythropoietin and darbepoetin
13.1
17.9
31
24
9875/3-C42.1
ICD-O-3
Chronic myelogenous leukemia, BCR/ABL positive of bone marrow
+∞
17.7
17
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
16.6
298
1730
D73.5
ICD-10 Finland
Infarction of spleen
16.4
16.5
26
16
L03AA02
ATC
filgrastim; parenteral
3.1
16.1
90
299
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.9
16.1
262
1473
WW200
NOMESCO Finland
Immunization
3.2
16.0
84
267
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
18.6
16.0
24
13
I81
ICD-10 Finland
Portal vein thrombosis
9.2
15.7
32
35
PH_2
NOMESCO Finland
Other procedures on veins
+∞
15.6
15
*
170
Kela drug reimbursment
Bosutinib
+∞
15.6
15
*
S97
ICPC
Chronic ulcer skin
2.3
15.6
154
707
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
38.3
15.4
19
5
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
9.8
15.2
30
31
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
17.8
15.1
23
13
B01AA03
ATC
warfarin; systemic
1.5
14.9
567
4033
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
14.2
508
3560
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.8
14.0
90
328
J01MA12
ATC
levofloxacin; systemic
1.5
13.7
454
3127
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.0
13.7
185
974
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.2
13.6
135
621
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.2
13.5
142
672
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.1
13.1
153
758
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
12.6
373
2494
2387X
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Other lymphatic and haematopoietic tissues[STATUS LYMPHO- ET MYELOPROLIFERATIVUS NUD]
70.2
12.6
14
*
D64.9
ICD-10 Finland
Anaemia, unspecified
1.7
12.5
263
1603
2387B
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Other lymphatic and haematopoietic tissues[THROMBOCYTHAEMIA IDIOPATHICA]
+∞
12.5
12
*
D69.1
ICD-10 Finland
Qualitative platelet defects
24.4
12.5
17
7
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
3.0
12.4
72
248
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.0
12.2
163
850
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
12.1
411
2839
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
12.0
539
3948
L04AD01
ATC
ciclosporin; systemic
3.3
11.9
59
182
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.7
11.8
250
1528
SPAT1088
SPAT
Blood transfusion
7.4
11.7
27
37
B73
ICPC
Leukaemia
16.5
11.7
18
11
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
12.6
11.6
20
16
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
5.5
11.5
33
61
L01XE14
ATC
[U] bosutinib; oral
+∞
11.5
11
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
11.4
428
3023
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
25.1
11.1
15
6
A02BC02
ATC
pantoprazole; systemic
1.3
11.1
1543
13599
ZX120
NOMESCO Finland
Intravenous
1.7
11.0
233
1423
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.4
11.0
88
368
M10.9
ICD-10 Finland
Gout, unspecified
1.9
10.9
169
935
C90.0
ICD-10 Finland
Multiple myeloma
3.5
10.8
48
137
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.7
10.8
210
1250
D68.8
ICD-10 Finland
Other specified coagulation defects
5.2
10.7
32
62
D47.7
ICD-10 Finland
Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
21.5
10.7
15
7
D75
ICD-10 Finland
Other diseases of blood and blood-forming organs
60.2
10.6
12
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.2
10.6
102
466
121
Kela drug reimbursment
Severe hypofunction of sexual glands
3.1
10.5
57
189
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
10.4
489
3606
B86
ICPC
OTHER HAEMATOLOGICAL ABNORMALITY
110.4
10.4
11
*
360
Kela drug reimbursment
Bosutinib
+∞
10.4
10
*
2387A
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Other lymphatic and haematopoietic tissues[MYELOFIBROSIS]
+∞
10.4
10
*
J01MA14
ATC
moxifloxacin; systemic
1.7
10.4
203
1210
C95.9
ICD-10 Finland
Leukaemia, unspecified
18.8
10.3
15
8
J01DB01
ATC
cefalexin; oral
1.3
10.2
1913
17511
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
1.9
9.9
143
772
H02AB06
ATC
prednisolone; systemic
1.3
9.7
1075
9100
XW000
SPAT
NA
55.2
9.6
11
*
R71
ICD-10 Finland
Abnormality of red blood cells
11.4
9.6
17
15
R72
ICD-10 Finland
Abnormality of white blood cells, not elsewhere classified
8.4
9.5
20
24
D46.2
ICD-10 Finland
Refractory anaemia with excess of blasts [RAEB]
17.6
9.4
14
8
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
4.3
9.4
33
77
2051A
ICD-9 Finland
Myeloid leukaemia, Chronic
+∞
9.4
9
*
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.7
9.1
226
3298
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
9.0
586
4568
I82.0
ICD-10 Finland
Budd-Chiari syndrome
24.1
8.9
12
5
C07AB07
ATC
bisoprolol; oral
1.3
8.9
1175
10151
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.6
8.8
266
1780
K99
ICPC
Cardiovascular disease other
2.2
8.8
82
372
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
9.5
8.8
17
18
V03AC03
ATC
deferasirox; oral
50.1
8.7
10
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
8.7
270
1821
C03DA01
ATC
spironolactone; oral
1.5
8.6
263
1769
I67.6
ICD-10 Finland
Nonpyogenic thrombosis of intracranial venous system
16.3
8.5
13
8
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.4
8.4
358
2586
C94.5
ICD-10 Finland
Acute myelofibrosis
+∞
8.3
8
*
L01EA04
ATC
bosutinib; oral
+∞
8.3
8
*
D47
ICD-10 Finland
Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
+∞
8.3
8
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
8.3
337
2409
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
8.3
254
1708
A07AA02
ATC
nystatin; oral
1.8
8.3
148
863
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.5
8.2
60
240
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
2.2
8.2
81
379
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
1.7
8.1
165
1001
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
2.8
8.0
49
179
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.2
7.9
28
67
D73.1
ICD-10 Finland
Hypersplenism
13.1
7.9
13
10
N02AX02
ATC
tramadol; systemic, rectal
1.3
7.8
964
8205
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
2.5
7.7
58
239
D58.2
ICD-10 Finland
Other haemoglobinopathies
25.1
7.6
10
*
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
2.0
7.5
94
485
B59
ICPC
Blood and Immunity, Other therap proced/minor surg NEC
80.3
7.4
8
*
WW304
NOMESCO Finland
Transfer of stem cells from registered domestic donator
80.3
7.4
8
*
C92.2
ICD-10 Finland
Atypical chronic myeloid leukaemia, BCR/ABL- negative
+∞
7.3
7
*
373
Kela drug reimbursment
Ponatinib
+∞
7.3
7
*
H02AB09
ATC
hydrocortisone; systemic
2.5
7.3
52
208
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
9.4
7.3
14
15
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
4.9
7.3
22
45
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.6
7.3
31
88
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.7
7.3
162
1006
-69
ICPC
Other reason for encounter NEC
2.0
7.2
92
478
A46
ICD-10 Finland
Erysipelas
1.4
7.2
320
2330
AA1AD
NOMESCO Finland
CT of head and brain
1.3
7.0
555
4438
D46.0
ICD-10 Finland
Refractory anaemia without ring sideroblasts, so stated
10.0
7.0
13
13
JMA11
NOMESCO Finland
Laparoscopic total splenectomy
10.0
7.0
13
13
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
2.7
7.0
45
168
N02AA05
ATC
oxycodone; systemic
1.4
6.9
343
2541
L04AA01
ATC
[U] ciclosporin; systemic
2.8
6.9
41
148
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
6.7
6.8
16
24
M01AE01
ATC
ibuprofen; systemic, rectal
0.8
6.7
1828
19508
C92.7
ICD-10 Finland
Other myeloid leukaemia
22.6
6.7
9
*
DKW00
NOMESCO Finland
Cauterisation of mucosa of nose
3.3
6.7
31
95
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
2.3
6.6
56
243
J02AC03
ATC
voriconazole; systemic
7.8
6.6
14
18
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
12.3
6.6
11
9
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.5
6.5
219
1508
R51.80
ICD-10 Finland
Headache
1.4
6.4
260
1855
C92.5
ICD-10 Finland
Acute myelomonocytic leukaemia
70.0
6.4
7
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.4
6.4
367
2794
L04AA06
ATC
mycophenolic acid; systemic
2.8
6.4
38
138
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
6.3
312
2311
L01XE24
ATC
[U] ponatinib; oral
+∞
6.3
6
*
R89.8
ICD-10 Finland
Abnormal findings in specimens from other organs, systems and tissues, other abnormal findings
26.7
6.2
8
*
B83
ICPC
Purpura/coagulation defect
26.7
6.2
8
*
XQ848
NOMESCO Finland
Dermatological photography
2.1
6.2
64
306
K93
ICPC
Pulmonary embolism
3.2
6.2
30
95
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.6
6.2
142
894
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.5
6.2
174
1150
9989/3-C42.1
ICD-O-3
Myelodysplastic syndrome, NOS, of bone marrow
7.7
6.1
13
17
R60.0
ICD-10 Finland
Localized oedema
1.4
6.1
246
1758
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
2.1
6.0
60
283

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
2635
15131
5.34
314.19
22.2
8.6
5.2
4.2
e9/l
21.21
2468
13129
849
409
27.96
307.65
1.3
1.2
29.7
45.3
u/l
0.88
703
356
2498
12175
5.92
307.65
18.1
6.0
8.4
8.8
%
8.88
2432
11318
2498
12125
5.95
307.65
17.2
5.7
2.7
2.9
%
2.41
2431
11225
2558
12952
6.00
307.65
15.5
5.5
0.1
0.0
e9/l
71.11
2372
11094
857
2024
5.43
307.65
9.8
3.7
1.2
0.5
%
8.00
319
462
661
270
30.65
307.65
1.3
1.3
—
—
—
0
0
2565
13220
5.87
307.65
15.8
5.6
2.0
1.9
e9/l
0.25
2417
11515
2586
13389
6.00
307.65
17.0
5.7
0.2
0.2
e9/l
5.53
2415
11623
2475
11807
5.96
307.65
17.0
5.8
1.0
0.7
%
83.58
2404
10947
2553
12890
5.99
307.65
15.5
5.5
0.6
0.6
e9/l
1.41
2368
11026
568
224
30.66
307.65
1.2
1.2
—
—
—
0
0
853
2127
5.11
307.65
10.1
3.9
0.2
0.1
%
3.39
419
603
2507
12437
5.81
307.65
17.7
5.9
24.9
27.1
%
18.29
2439
11501
1422
3261
7.08
307.65
4.2
2.4
1.9
1.8
%
2.60
1274
2863
776
441
22.96
307.65
1.5
1.5
—
—
—
0
0
935
2225
5.54
307.65
10.1
3.9
1.5
0.8
%
7.09
439
647
1202
2433
7.34
307.65
4.0
2.5
77.9
68.9
e9/l
11.31
899
1866
1847
7050
4.87
307.65
4.8
2.7
1534.0
5866.3
umol/l
8.09
1720
6016
2102
8990
4.95
307.65
16.0
5.5
—
—
—
0
0
2475
12249
5.61
307.65
16.0
5.7
60.6
57.8
%
25.42
2399
11377
1138
3741
4.18
303.08
2.8
2.6
22.5
22.3
%
0.10
1002
3182
791
1992
4.96
298.02
10.2
4.0
1.0
0.2
%
1.55
341
500
1156
3994
3.98
284.31
2.7
2.5
2.4
2.3
g/l
10.15
1097
3685
1203
4299
3.89
281.20
2.8
2.5
13.1
12.6
umol/l
1.45
1144
3970
1279
5382
3.30
222.29
12.8
4.4
—
—
—
0
0
2324
14096
3.41
209.85
10.7
6.2
12.2
11.7
umol/l
0.91
2263
13340
299
460
7.07
187.94
8.7
3.2
1.8
1.4
%
1.05
231
349
1833
10591
2.73
163.70
4.0
2.8
160.4
141.9
ug/l
0.85
1709
9664
470
1336
3.95
144.52
1.8
1.8
1.1
1.5
g/l
19.40
404
1146
1858
11417
2.51
136.60
21.7
9.7
0.1
0.0
e9/l
4.23
1663
9304
187
290
6.79
115.88
9.1
3.2
65.3
56.8
%
3.57
109
178
1278
7049
2.36
113.67
2.7
2.2
4.8
3.0
mg/l
21.97
1101
5961
248
517
5.12
112.65
5.6
3.5
61.1
57.6
%
3.03
248
517
187
307
6.41
109.61
10.8
3.7
—
—
—
0
0
2042
13899
2.31
107.75
8.8
6.8
1.2
1.2
mmol/l
0.08
1726
11650
2670
20575
2.86
105.85
16.4
7.6
84.0
79.4
u/l
4.86
2603
19304
103
93
11.41
98.10
1.1
1.1
—
—
—
0
0
1379
8262
2.18
96.27
6.3
4.0
7.4
7.4
ph
3.63
279
1585
68
28
24.79
96.22
1.0
1.1
—
—
—
0
0
154
247
6.50
92.22
1.1
1.1
—
—
—
0
0
752
3634
2.40
86.64
5.9
5.6
1.0
1.0
mmol/l
0.27
711
3348
1834
12622
2.07
84.97
8.0
6.0
1.2
1.2
mmol/l
4.24
1691
11342
1142
6714
2.09
80.15
14.9
6.4
—
—
—
0
0
82
78
10.76
75.32
1.8
1.6
—
—
—
0
0
836
4500
2.16
72.71
4.6
3.2
0.8
0.8
mmol/l
1.54
797
4181
427
1735
2.69
69.85
4.9
3.2
5.8
4.1
e9/l
3.50
287
1299
226
656
3.63
65.87
3.5
2.9
1.4
1.6
mg/l
6.46
218
589
1695
11984
1.89
65.51
6.5
4.7
35.5
35.1
g/l
2.79
1597
11110
1094
6750
1.95
63.83
1.8
1.6
20.2
20.5
nmol/l
0.23
970
5690
98
145
6.94
63.24
1.9
1.5
—
—
—
0
0
598
2957
2.26
63.24
5.3
2.6
7.0
8.7
umol/l
1.75
544
2580
1634
11554
1.85
61.75
2.4
2.0
91.5
94.2
pmol/l
1.57
1013
5864
435
1892
2.51
61.45
2.8
2.8
10.0
10.6
g/l
1.51
397
1711
516
2440
2.33
60.45
2.7
2.6
66.5
66.3
g/l
0.19
472
2216
1083
6804
1.90
58.78
5.7
3.9
84.1
87.9
%
4.64
1026
6635
2065
16017
1.83
54.56
5.9
4.7
6.6
6.8
mmol/l
5.31
1991
15050
750
4272
1.99
53.73
2.9
2.0
31.8
29.9
s
10.72
708
4141
352
1488
2.54
52.44
1.9
1.9
1.5
1.4
g/l
0.17
319
1341
257
928
2.93
52.08
2.7
2.0
22.4
21.6
s
0.64
228
827
426
2053
2.24
46.96
2.6
2.4
—
—
—
0
0
894
5682
1.80
44.27
2.0
1.7
1.2
1.4
mg/l
1.06
698
4382
2330
19380
1.76
41.68
5.3
4.2
12.1
13.3
mm/h
2.87
2188
17816
863
5565
1.76
39.97
1.9
1.8
1108.0
1177.7
nmol/l
1.44
666
4139
225
924
2.54
35.27
3.3
3.4
1.6
1.7
ratio
0.01
22
73
229
952
2.51
34.98
3.3
3.4
54.2
119.9
mg/l
0.54
201
766
229
952
2.51
34.98
3.3
3.4
36.9
68.5
mg/l
1.31
202
768
1503
11567
1.57
32.90
12.7
10.1
1.4
1.3
inr
1.15
477
3242
253
1150
2.30
31.64
2.8
2.4
3.5
3.8
g/l
2.56
175
831
125
399
3.22
31.25
1.3
1.4
152.5
119.8
u/ml
0.39
22
79
238
1076
2.31
30.12
2.8
2.4
11.0
10.3
g/l
1.31
190
915
40
51
7.93
29.39
3.7
1.4
—
—
—
0
0
299
1515
2.07
28.42
1.3
1.4
—
—
—
0
0
130
452
2.96
28.08
1.3
1.3
—
—
—
0
0
1073
7881
1.55
27.50
6.0
4.3
—
—
—
0
0
84
225
3.81
27.48
1.5
1.8
3.1
4.5
mg/l
4.05
79
219
73
180
4.13
26.77
2.1
2.0
30.9
45.2
%
—
10
23
43
68
6.40
26.07
1.0
1.0
—
—
—
0
0
432
2548
1.80
25.99
6.0
7.1
9.9
10.4
mmol/l
0.89
408
2417
172
723
2.46
25.61
3.4
3.5
—
—
—
0
0
30
6
50.44
25.24
1.8
3.3
—
—
—
0
0
1092
8179
1.51
24.97
4.6
3.2
33.6
38.7
u/l
1.10
1045
7742
41
66
6.28
24.44
1.6
1.1
—
—
—
0
0
1148
8726
1.49
24.27
3.4
3.1
2203.8
1557.2
ng/l
2.12
1009
7518
197
905
2.25
23.95
2.9
2.2
38.6
37.6
g/l
1.42
168
781
147
595
2.54
23.72
1.2
1.2
—
—
—
0
0
397
2344
1.79
23.68
3.3
3.9
1.2
1.2
mmol/l
2.38
344
2038
152
626
2.50
23.65
1.7
1.6
—
—
—
0
0
73
199
3.73
23.33
1.2
1.2
—
—
—
0
0
64
159
4.09
23.26
3.9
2.0
2275.4
698.2
e6/l
0.44
28
71
75
209
3.65
23.21
2.5
2.4
—
—
—
0
0
663
4522
1.59
22.84
1.5
1.5
2.3
2.6
g/l
1.72
426
2661
111
397
2.86
22.81
1.2
1.2
315.8
268.8
u/ml
0.75
74
243
400
2399
1.76
22.57
1.4
1.5
—
—
—
0
0
503
3216
1.67
22.47
1.3
1.3
400.0
546.5
titre
1.44
101
692
439
2716
1.72
22.16
1.5
1.5
—
—
—
0
0
35
53
6.67
22.12
6.1
2.6
43.2
36.4
u/l
0.36
17
16
1109
8557
1.45
20.92
5.2
2.4
—
—
—
0
0
74
222
3.39
20.51
3.9
2.0
0.8
1.1
e9/l
1.71
39
131
2781
25642
1.68
20.19
27.8
15.6
20.1
25.4
mg/l
16.75
2421
20647
58
149
3.95
20.18
4.2
2.0
1201.2
553.2
e6/l
0.50
48
127
28
37
7.63
19.95
1.5
1.4
—
—
—
0
0
56
142
4.00
19.84
4.4
2.0
0.2
0.2
e9/l
0.21
49
127
25
7
35.98
19.82
1.0
1.0
—
—
—
0
0
25
7
35.98
19.82
1.0
1.0
—
—
—
0
0
25
7
35.98
19.82
1.0
1.0
—
—
—
0
0
25
7
35.98
19.82
1.0
1.0
—
—
—
0
0
25
7
35.98
19.82
1.0
1.0
—
—
—
0
0
101
378
2.73
19.10
1.1
1.1
—
—
—
0
0
384
2415
1.67
18.04
1.4
1.4
—
—
—
0
0
471
3129
1.59
17.74
2.1
1.8
—
—
—
0
0
100
393
2.59
17.20
1.1
1.0
—
—
—
0
0
168
835
2.07
16.74
3.9
3.5
—
—
—
0
0
58
170
3.46
16.72
2.1
2.0
71.1
71.9
%
0.15
53
158
741
5491
1.46
16.56
3.2
2.8
543.3
544.2
mosm/kgh2o
0.04
658
4682
222
1227
1.87
16.27
2.1
1.9
1.4
2.5
ug/l
1.02
200
1070
51
140
3.69
16.21
2.0
2.7
34.8
39.3
%
0.37
13
51
56
165
3.44
16.03
2.1
2.0
16.3
14.4
%
0.30
23
63
347
2191
1.66
15.99
4.4
4.1
—
—
—
0
0
2309
20777
1.41
15.77
38.7
18.8
15.6
13.8
%
170.92
2293
20278
2619
24139
1.48
15.49
5.1
4.1
1.3
1.3
mmol/l
1.40
2468
21711
1066
8513
1.38
15.33
2.5
2.1
140.4
221.7
u/l
4.39
1003
7943
1477
12421
1.35
15.26
7.8
4.1
—
—
—
0
0
364
2356
1.62
15.16
2.1
2.2
398.6
370.4
nmol/l
1.58
337
2135
1171
9509
1.37
15.12
3.6
3.4
2.3
2.4
mmol/l
3.93
1022
8165
1058
8465
1.37
14.95
2.9
2.6
54.0
58.3
u/l
3.48
972
7777
18
20
9.05
14.66
1.3
1.5
—
—
—
0
0
1040
8358
1.36
14.10
3.8
3.3
57.5
86.3
e6/l
0.72
822
6476
933
7401
1.37
13.65
3.6
3.2
—
—
—
0
0
539
3884
1.47
13.64
2.1
2.0
—
—
—
0
0
286
1798
1.65
13.35
3.9
3.6
5.2
5.2
kpa
0.10
256
1653
841
6586
1.38
13.26
5.1
2.3
—
—
—
0
0
76
299
2.58
13.12
1.7
1.4
—
—
—
0
0
76
299
2.58
13.12
1.7
1.4
—
—
—
0
0
76
299
2.58
13.12
1.7
1.4
—
—
—
0
0
76
299
2.58
13.12
1.7
1.4
—
—
—
0
0
132
658
2.05
13.10
1.1
1.2
110.9
91.7
titre
0.23
11
48
281
1775
1.64
12.87
3.9
3.7
7.4
7.4
ph
0.09
32
223
850
6698
1.37
12.82
3.8
3.6
—
—
—
0
0
452
3193
1.48
12.58
1.6
1.7
—
—
—
0
0
40
112
3.60
12.42
1.6
2.5
1489.1
1239.4
u/ml
0.19
40
112
2027
18148
1.32
12.37
4.8
4.5
—
—
—
0
0
950
7662
1.34
12.20
3.7
3.2
0.5
0.5
e6/l
0.01
739
5836
693
5324
1.39
12.13
3.4
3.1
2.4
2.5
mmol/l
1.64
608
4670
79
330
2.43
12.06
1.2
1.2
4.8
5.4
u/ml
0.12
38
139
75
307
2.48
11.96
2.3
2.0
—
—
—
0
0
133
692
1.96
11.74
1.5
1.5
0.2
0.2
g/l
1.10
121
655
1479
12742
1.30
11.69
5.2
5.2
0.0
0.0
estimate
0.50
392
2395
19
30
6.37
11.54
1.1
1.0
—
—
—
0
0
381
2646
1.50
11.49
2.2
2.1
0.2
0.2
g/l
0.69
342
2452
33
86
3.87
11.36
1.3
1.2
—
—
—
0
0
748
5873
1.36
11.32
3.0
2.6
4.8
5.3
e6/l
0.54
675
5162
1492
12904
1.29
11.31
3.9
3.9
0.0
0.0
estimate
1.08
389
2325
171
977
1.79
11.30
2.4
2.2
265.7
745.1
ug/l
1.49
163
918
1811
16064
1.30
11.30
3.7
3.2
61.2
52.9
u/l
2.99
1713
14738
135
717
1.92
11.23
1.5
1.5
1.1
1.2
g/l
1.46
125
677
1473
12729
1.29
11.20
3.9
3.8
0.0
0.0
estimate
0.00
400
2364
77
330
2.37
11.13
1.1
1.2
—
—
—
0
0
1268
10752
1.30
11.12
4.3
3.9
45.3
99.5
ng/l
0.72
997
7869
126
657
1.96
11.07
1.8
1.9
15.9
11.9
mg/l
1.23
109
603
22
44
5.03
10.51
1.4
1.8
61.4
195.0
e6/l
2.16
14
18
2822
26825
1.46
10.23
29.2
18.3
139.4
139.6
mmol/l
3.62
2779
26128
255
1666
1.58
10.15
6.9
7.0
24.7
24.9
mmol/l
0.28
255
1656
404
2906
1.45
10.15
5.3
4.4
—
—
—
0
0
1141
9639
1.29
10.00
4.3
3.8
113.8
117.3
e6/l
0.05
865
6935
419
3055
1.43
9.77
1.9
1.4
—
—
—
0
0
2824
26888
1.45
9.74
30.9
18.5
4.0
4.0
mmol/l
6.13
2776
26150
229
1474
1.60
9.72
2.8
3.2
4.4
4.4
pmol/l
0.16
187
1280
1271
10933
1.27
9.49
2.6
2.2
78.3
78.6
nmol/l
0.15
1135
9623
2126
19457
1.28
9.40
4.3
4.0
15.1
14.9
pmol/l
1.96
1949
17466
27
71
3.83
9.22
1.2
1.1
—
—
—
0
0
2505
23451
1.32
9.15
5.3
4.8
2.0
2.1
mu/l
0.29
2345
21172
187
1166
1.64
9.04
1.3
1.2
—
—
—
0
0
100
520
1.95
8.92
1.2
1.4
57.1
60.7
mmol/l
0.47
81
412
22
53
4.17
8.45
1.1
1.1
—
—
—
0
0
2638
24952
1.34
8.44
5.6
4.6
1.3
1.5
mmol/l
60.20
2495
22645
31
96
3.25
8.34
2.5
2.0
—
—
—
0
0
2656
25161
1.34
8.30
5.6
4.6
4.2
4.6
mmol/l
81.16
2530
22995
110
607
1.84
8.22
2.6
2.5
16.3
16.0
%
0.20
56
312
116
652
1.81
8.17
4.6
4.8
8.2
8.4
kpa
0.59
116
642
17
34
5.02
8.13
1.1
1.4
8.9
282148.8
nmol/l
0.49
12
28
27
78
3.48
8.09
1.4
1.3
—
—
—
0
0
115
648
1.80
8.04
3.5
3.9
—
—
—
0
0
114
646
1.79
7.83
4.6
4.8
2.7
2.7
mmol/l
0.04
77
451
114
647
1.79
7.80
4.6
4.8
5.0
5.1
kpa
0.21
114
638
52
221
2.38
7.77
2.1
2.3
—
—
—
0
0
111
631
1.79
7.56
2.9
2.9
7.7
7.9
kpa
1.02
105
578
195
1287
1.55
7.47
4.4
3.8
—
—
—
0
0
98
540
1.84
7.40
2.9
2.8
—
—
—
0
0
433
3326
1.35
7.30
7.2
7.0
5.0
5.1
kpa
1.92
415
3164
433
3326
1.35
7.30
7.2
7.0
11.9
12.0
kpa
0.12
413
3164
77
395
1.97
7.21
1.1
1.2
—
—
—
0
0
169
1090
1.58
7.17
4.4
4.0
24.4
24.9
mmol/l
1.08
152
1004
303
2204
1.41
7.12
3.5
3.8
88.5
94.1
ng/l
0.55
261
1872
358
2690
1.37
6.94
3.7
3.5
5.8
5.9
kpa
0.57
348
2608
68
339
2.03
6.91
1.3
1.4
66.9
53.0
mu/l
0.17
57
299
1916
17602
1.22
6.91
5.1
4.8
2824.6
2217.4
e6/l
0.09
23
272
356
2679
1.37
6.84
3.7
3.5
1.7
2.0
mmol/l
0.92
291
2150
823
6935
1.25
6.81
4.2
4.3
0.0
0.0
estimate
0.88
381
2284
331
2467
1.38
6.75
2.4
2.5
32.6
57.8
u/l
0.71
288
2116
36
138
2.63
6.71
1.9
1.5
—
—
—
0
0
42
174
2.43
6.68
1.8
1.4
1611.5
1762.9
ml
—
8
38
145
918
1.61
6.67
1.2
1.2
0.2
1.0
u/ml
—
8
80
388
2971
1.35
6.67
7.6
7.4
95.1
95.5
%
0.51
375
2856
427
3317
1.33
6.66
7.4
7.0
1.1
1.1
mmol/l
0.05
330
2583
2826
27191
1.35
6.61
23.6
10.9
25.4
25.9
u/l
1.00
2770
26110
474
3743
1.31
6.58
1.3
1.2
—
—
—
0
0
20
55
3.65
6.47
1.1
1.1
—
—
—
0
0
336
2531
1.37
6.41
6.5
6.5
1.5
1.4
mmol/l
0.78
324
2439
2692
25748
1.30
6.39
6.1
5.2
2.4
2.7
mmol/l
58.13
2556
23400
121
743
1.65
6.30
3.1
3.2
25.1
25.1
mmol/l
0.00
112
641
669
5551
1.26
6.27
4.1
3.9
592.9
584.2
ng/l
0.01
544
4551
316
2367
1.37
6.25
7.7
7.9
—
—
—
0
0
992
8599
1.22
6.21
3.4
3.4
—
—
—
0
0
43
187
2.32
6.17
1.1
1.2
125.0
115.3
titre
—
6
34
267
1951
1.40
6.13
4.9
4.7
—
—
—
0
0
62
314
1.99
6.08
1.2
1.5
—
—
—
0
0
490
3942
1.29
5.89
32.0
26.7
1.5
1.4
inr
0.81
77
555
19
54
3.53
5.88
1.1
1.1
—
—
—
0
0
121
766
1.60
5.62
4.5
4.5
7.4
7.4
ph
0.22
114
637
41
183
2.26
5.57
1.1
1.2
35.4
33.2
mmol/l
0.26
36
158
213
1522
1.43
5.57
8.5
9.0
24.4
24.4
mmol/l
0.01
203
1424
61
318
1.94
5.54
1.1
1.4
292.2
291.6
pmol/l
0.00
48
244
449
3613
1.28
5.37
7.8
6.6
104.0
104.2
mmol/l
0.50
442
3527
2521
24044
1.23
5.36
6.4
6.2
38.5
40.4
mmol/mol
23.17
2375
22020
63
336
1.89
5.36
1.3
1.4
113387.5
92817.7
e6/l
0.14
38
198
10
18
5.57
5.32
1.1
1.0
—
—
—
0
0
18
53
3.41
5.30
1.1
1.2
—
—
—
0
0
191
1356
1.43
5.19
1.4
1.3
—
—
—
0
0
37
164
2.27
5.14
4.9
3.8
—
—
—
0
0
535
4420
1.25
5.13
3.4
3.0
1.8
2.4
e6/l
1.33
283
2432
73
414
1.78
5.13
1.3
1.5
31.5
32.2
g/l
0.19
66
374
21
70
3.01
5.10
1.0
1.1
—
—
—
0
0
62
1096
0.56
5.06
1.5
1.5
—
—
—
0
0
82
487
1.70
4.92
2.3
3.1
—
—
—
0
0
1991
18634
1.18
4.90
4.6
4.0
—
—
—
0
0
2385
22687
1.21
4.86
33.1
16.7
39.0
39.2
%
0.42
1516
15159
186
1333
1.42
4.82
4.3
3.7
24.1
24.2
mmol/l
0.13
175
1191
66
378
1.76
4.53
1.3
1.4
1913.2
1808.7
e6/l
0.08
46
274
20
70
2.87
4.49
1.3
1.4
—
—
—
0
0
364
2933
1.27
4.31
1.2
1.3
—
—
—
0
0
73
439
1.68
4.23
1.1
1.3
—
—
—
0
0
37
179
2.08
4.21
1.5
1.2
—
—
—
0
0
11
27
4.08
4.16
2.8
1.1
—
—
—
0
0
11
27
4.08
4.16
3.0
1.9
—
—
—
0
0
11
27
4.08
4.16
2.8
1.1
—
—
—
0
0
11
27
4.08
4.16
2.8
1.1
—
—
—
0
0
1172
10608
1.17
4.12
2.4
2.2
—
—
—
0
0
8
10
8.02
4.06
3.4
1.3
—
—
—
0
0
932
8298
1.17
4.02
4.5
4.2
—
—
—
0
0
90
580
1.57
3.98
2.2
2.9
36.9
37.0
umol/l
0.01
72
484
2603
25107
1.20
3.89
5.2
4.9
6.0
6.0
mmol/l
0.82
2381
22606
280
2214
1.29
3.86
3.0
2.9
4.6
4.6
kpa
0.18
273
2141
16
54
2.97
3.84
1.5
1.4
—
106.0
titre
—
0
11
164
1201
1.39
3.81
4.6
5.3
1.9
1.6
%
1.46
152
1123
21
83
2.54
3.79
2.3
2.1
—
—
—
0
0
320
2582
1.27
3.76
3.5
3.0
224.0
220.7
ng/l
0.05
296
2351
31
149
2.09
3.62
1.0
1.1
—
—
—
0
0
335
2737
1.25
3.55
8.4
7.8
118.2
121.2
g/l
1.43
324
2637
60
361
1.67
3.53
1.7
1.6
0.8
0.8
g/l
0.26
45
273
39
208
1.89
3.44
1.4
2.6
—
—
—
0
0
18
70
2.58
3.38
2.7
1.9
—
—
—
0
0
34
175
1.95
3.33
1.3
1.3
—
—
—
0
0
74
478
1.56
3.30
1.6
1.3
12.7
10.3
u/l
0.80
66
385
548
4739
1.19
3.29
3.2
2.8
0.9
1.2
e6/l
1.09
297
2730
57
346
1.66
3.27
1.4
1.2
—
—
—
0
0
61
378
1.63
3.24
1.3
1.3
0.2
0.4
nmol/l
—
5
25
337
2785
1.23
3.23
2.2
2.2
190.5
155.5
ug/g
0.56
268
2169
22
97
2.28
3.19
1.5
1.5
3.8
3.2
%
0.09
22
81
50
298
1.69
3.09
1.3
1.3
272.0
277.3
mosm/kgh2o
0.93
42
223
53
321
1.66
3.09
1.3
1.6
—
—
—
0
0
49
295
1.67
2.93
1.3
1.2
—
—
—
0
0
32
170
1.89
2.90
2.4
1.6
—
—
—
0
0
91
633
1.45
2.90
2.2
2.2
131.3
127.9
g/l
0.41
70
459
90
628
1.45
2.83
1.2
1.2
1.8
3.8
u/ml
—
5
59
28
144
1.95
2.79
1.0
1.0
—
—
—
0
0
63
410
1.55
2.77
2.4
2.7
—
—
—
0
0
9
23
3.92
2.77
1.0
1.0
—
—
—
0
0
32
173
1.86
2.76
2.7
2.9
—
—
—
0
0
155
1189
1.32
2.75
4.8
5.3
0.9
0.9
%
0.64
143
1114
20
91
2.21
2.73
27.6
30.0
6.9
7.4
ug/l
0.39
15
79
16
66
2.43
2.70
1.1
1.0
—
—
—
0
0
38
220
1.74
2.64
1.6
1.8
—
—
—
0
0
95
681
1.41
2.60
1.4
1.3
26.8
31.3
iu/l
0.81
85
578
459
3990
1.18
2.59
1.2
1.2
10.3
13.0
u/ml
0.40
156
1492
32
178
1.81
2.55
1.1
1.1
—
—
—
0
0
582
5165
1.16
2.52
1.3
1.2
2.1
1.5
u/ml
0.35
109
1307
19
88
2.17
2.50
2.2
2.1
1335.8
23277.4
e6/l
0.54
13
50
477
4174
1.17
2.48
1.3
1.3
26.7
38.0
iu/ml
1.51
153
1317
119
1561
0.75
2.41
1.4
1.4
—
—
—
0
0
180
1438
1.27
2.39
3.2
3.2
24.7
25.3
mmol/l
1.64
172
1390
227
1864
1.23
2.37
1.2
1.2
—
—
—
0
0
26
140
1.86
2.31
1.7
2.4
—
—
—
0
0
38
231
1.65
2.26
1.2
1.4
—
—
—
0
0
21
106
1.99
2.25
1.2
1.2
—
—
—
0
0
43
271
1.59
2.23
1.1
1.1
—
—
—
0
0
55
367
1.51
2.22
2.5
2.5
—
—
—
0
0
38
603
0.63
2.21
1.2
1.2
—
—
—
0
0
27
150
1.81
2.20
1.1
1.3
—
—
—
0
0
220
1820
1.22
2.16
8.2
6.8
24.1
24.6
mmol/l
0.87
206
1694
26
144
1.81
2.14
1.2
1.4
1.3
1.2
nmol/l
0.12
17
113
102
768
1.34
2.13
1.2
1.2
—
—
—
0
0
13
55
2.37
2.12
1.3
1.5
—
—
—
0
0
19
95
2.01
2.10
1.4
1.3
—
—
—
0
0
16
75
2.14
2.08
1.1
1.3
—
—
—
0
0
17
82
2.08
2.06
1.1
1.3
51.4
455.3
ug/l
—
10
40
46
302
1.53
2.03
1.3
1.5
—
—
—
0
0
21
111
1.90
2.00
2.0
2.5
—
—
—
0
0
35
216
1.63
2.00
1.3
1.2
—
—
—
0
0
107
820
1.32
2.00
1.4
1.5
285.8
274.9
ug/g
0.24
65
476
49
328
1.50
1.98
1.2
1.3
—
—
nmol/l
—
0
0
47
312
1.51
1.98
1.2
1.2
—
—
—
0
0
56
386
1.46
1.97
2.4
2.5
—
—
—
0
0
188
1548
1.23
1.96
10.3
9.7
—
—
—
0
0
20
106
1.89
1.90
2.0
2.8
66.8
104.5
umol/l
0.58
11
58
36
228
1.59
1.87
1.1
1.4
2.4
3.0
g/l
1.12
24
158
36
228
1.59
1.87
1.1
1.4
0.4
0.4
g/l
0.12
24
158
36
228
1.59
1.87
1.1
1.4
6.5
7.2
g/l
0.48
25
158
9
34
2.65
1.86
1.1
1.1
—
—
—
0
0
755
6943
1.11
1.85
1.6
1.6
1.5
1.4
mmol/l
2.15
648
5765
19
100
1.91
1.85
2.2
2.3
560.4
776.1
e6/l
0.43
13
76
6
17
3.53
1.83
1.0
1.0
—
—
—
0
0
6
17
3.53
1.83
1.0
1.0
—
—
—
0
0
5
12
4.17
1.82
1.0
1.0
46.1
35.2
s
—
5
12
8
183
0.44
1.80
1.5
1.5
—
—
—
0
0
36
231
1.56
1.78
1.4
1.2
360.7
358.2
nmol/l
0.02
31
197
44
297
1.49
1.75
5.0
3.6
—
—
—
0
0
26
155
1.68
1.72
1.7
2.2
—
—
—
0
0
178
1481
1.21
1.71
3.6
3.6
—
—
—
0
0
8
176
0.45
1.69
1.5
1.4
—
—
—
0
0
8
176
0.45
1.69
1.5
1.4
—
—
—
0
0
181
1513
1.21
1.66
2.4
2.5
—
—
—
0
0
17
90
1.89
1.65
1.6
1.4
17.1
23.2
%
0.52
17
82
723
6677
1.11
1.63
1.5
1.3
—
—
—
0
0
2853
28110
1.15
1.56
47.6
22.9
384.2
245.7
e9/l
288.69
2808
27323
79
606
1.31
1.53
2.1
1.8
40.4
42.1
nmol/l
0.28
74
576
2853
28117
1.14
1.52
47.3
22.9
93.9
91.4
fl
30.66
2827
27638
2853
28118
1.14
1.51
47.2
22.8
30.7
30.4
pg
3.41
2827
27637
7
27
2.60
1.51
1.0
1.1
—
—
—
0
0
2853
28120
1.14
1.50
47.5
22.9
4.4
4.4
e12/l
2.99
2797
27236
2688
26399
1.12
1.50
25.0
14.9
—
—
—
0
0
12
58
2.07
1.49
1.4
1.4
—
—
—
0
0
209
1791
1.18
1.49
2.7
3.0
125.7
127.9
g/l
0.63
199
1741
2853
28126
1.14
1.47
47.8
23.1
131.0
134.3
g/l
19.47
2826
27654
2853
28126
1.14
1.47
47.6
23.0
8.9
6.8
e9/l
28.33
2799
27243
28
179
1.57
1.45
2.0
1.6
—
—
—
0
0
96
763
1.27
1.44
4.3
4.6
—
—
—
0
0
43
304
1.42
1.40
1.6
1.5
—
—
—
0
0
9
41
2.20
1.37
1.0
1.0
—
—
—
0
0
6
23
2.61
1.36
1.0
1.1
—
—
—
0
0
43
306
1.41
1.36
1.7
2.8
—
—
—
0
0
658
6104
1.10
1.36
1.6
1.7
21022097.8
26562929.9
pmol/l
0.10
509
4992
2034
20904
0.93
1.33
42.4
20.3
326.4
331.9
g/l
54.88
2021
20725
387
3498
1.12
1.31
1.3
1.3
—
—
—
0
0
25
160
1.57
1.31
1.4
1.5
1.0
1.0
g/l
0.02
25
160
6
24
2.50
1.30
1.7
2.8
—
—
—
0
0
26
169
1.54
1.28
2.3
2.1
491.5
487.9
min
0.06
15
124
6
25
2.40
1.24
1.0
1.1
—
—
—
0
0
498
5405
0.91
1.23
2.8
3.1
0.8
0.8
ug/l
0.22
340
3719
43
313
1.38
1.22
8.4
6.8
7.5
7.6
mmol/l
0.06
36
265
33
229
1.45
1.21
2.4
2.3
690.4
628.0
ml
0.37
19
149
207
1807
1.16
1.21
2.9
2.2
12.8
12.7
nmol/l
0.00
187
1573
146
1243
1.18
1.17
1.5
1.5
—
—
—
0
0
23
150
1.54
1.14
3.2
2.7
7.4
7.4
ph
—
9
51
163
1408
1.17
1.11
1.3
1.3
192.2
218.6
u/ml
0.22
153
1291
13
74
1.76
1.06
3.2
1.9
—
—
—
0
0
8
148
0.54
1.03
1.1
1.1
—
—
—
0
0
85
698
1.22
1.03
3.4
3.2
0.8
0.8
nmol/l
0.41
63
542
13
75
1.74
1.02
1.2
1.1
—
—
—
0
0
48
368
1.31
1.01
1.4
1.9
32305.2
2024.4
u/l
1.00
13
144
658
6186
1.08
1.01
3.5
3.8
—
—
—
0
0
10
53
1.89
1.01
1.4
2.0
—
—
—
0
0
123
1049
1.18
1.00
2.4
3.2
414.7
4792.2
u/ml
0.94
105
884
61
486
1.26
0.97
1.2
1.2
252.2
215.2
miu/ml
0.23
19
193
78
945
0.82
0.96
1.7
1.7
—
—
—
0
0
136
1176
1.16
0.95
5.7
4.4
—
—
—
0
0
7
37
1.89
0.94
1.1
1.1
—
—
—
0
0
104
881
1.19
0.93
5.4
3.9
4.0
3.9
mmol/l
1.07
99
819
30
217
1.39
0.93
5.1
4.9
47.5
40.9
u/ml
—
10
57
46
357
1.29
0.91
1.3
1.8
—
—
—
0
0
13
78
1.67
0.91
2.6
2.0
—
—
—
0
0
22
151
1.46
0.90
6.9
6.3
—
—
—
0
0
11
63
1.75
0.90
2.7
2.4
—
—
—
0
0
289
2635
1.11
0.89
2.3
2.4
5.2
7.1
ug/l
2.04
229
2294
54
430
1.26
0.88
1.3
2.0
—
—
—
0
0
68
557
1.23
0.87
1.5
1.4
28.0
28.0
e6/l
0.00
54
425
68
557
1.23
0.87
1.6
1.4
947.6
1349.7
e6/l
0.18
57
449
77
640
1.21
0.86
1.4
1.1
—
—
—
0
0
165
1461
1.14
0.85
1.2
1.2
92.6
141.0
iu/ml
1.25
58
521
6
32
1.88
0.81
1.5
1.2
29.8
36.9
nmol/l
—
6
26
165
1467
1.13
0.81
3.3
2.9
0.3
0.3
e6/l
0.21
160
1436
190
1705
1.12
0.80
2.6
2.4
26.4
23.9
au/ml
—
9
76
17
114
1.49
0.79
1.1
1.3
—
—
—
0
0
14
90
1.56
0.78
1.2
1.2
38.1
38.8
g/l
—
7
45
15
222
0.67
0.77
1.0
1.0
—
—
—
0
0
77
649
1.19
0.77
7.1
7.2
11.8
11.2
mmol/l
0.87
68
578
77
649
1.19
0.77
7.1
7.2
105.2
105.2
mmol/l
0.04
68
578
19
132
1.44
0.76
1.7
2.5
2132.6
1876.4
ml
0.46
19
113
112
976
1.15
0.75
2.9
3.0
0.5
0.3
g/l
0.89
51
367
331
3069
1.09
0.75
3.0
4.0
13.9
22.6
ug/l
0.49
253
2522
5
24
2.08
0.74
1.4
1.1
—
—
—
0
0
50
405
1.24
0.74
1.3
1.3
—
—
—
0
0
33
254
1.30
0.73
1.8
1.5
—
—
—
0
0
252
2311
1.10
0.73
1.6
1.5
—
—
—
0
0
5
25
2.00
0.72
3.4
3.0
—
—
—
0
0
5
25
2.00
0.72
6.8
5.9
—
—
—
0
0
5
25
2.00
0.72
1.0
1.2
—
—
—
0
0
36
457
0.79
0.72
1.6
1.7
—
—
—
0
0
56
676
0.83
0.72
1.0
1.1
—
—
—
0
0
7
42
1.67
0.68
1.1
1.6
—
—
—
0
0
34
267
1.28
0.66
1.6
1.4
—
—
—
0
0
5
28
1.79
0.66
1.8
1.3
—
640.5
—
0
9
74
862
0.86
0.65
18.1
10.6
—
—
—
0
0
40
322
1.25
0.65
1.5
1.2
—
—
—
0
0
24
180
1.34
0.65
1.1
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
61
519
1.18
0.59
1.4
1.4
—
—
—
0
0
0
23
0.00
0.58
0.0
1.8
—
—
—
0
0
55
465
1.19
0.57
1.4
1.9
—
—
—
0
0
6
35
1.72
0.57
1.0
1.2
2.6
1.9
umol/24h
—
6
35
20
149
1.34
0.57
10.1
13.5
—
—
—
0
0
15
207
0.72
0.56
1.0
1.0
888.8
689.2
ng/l
—
10
132
55
467
1.18
0.55
1.4
1.9
—
—
—
0
0
15
206
0.73
0.55
1.0
1.0
277.3
322.7
ng/l
—
10
134
22
168
1.31
0.55
1.8
1.3
3.0
1.3
u/ml
0.27
17
86
55
469
1.18
0.53
1.3
1.9
—
—
—
0
0
11
75
1.47
0.50
1.0
1.0
—
—
—
0
0
13
179
0.73
0.50
1.0
1.5
—
72.4
—
0
12
52
605
0.86
0.49
1.4
1.3
—
—
—
0
0
129
1174
1.10
0.49
2.5
2.7
—
—
—
0
0
101
907
1.12
0.49
1.6
1.6
—
—
—
0
0
195
1812
1.08
0.47
3.2
3.2
—
—
—
0
0
22
173
1.27
0.46
1.2
1.1
7.5
7.5
nmol/l
—
5
38
35
291
1.21
0.46
1.6
1.1
—
—
—
0
0
35
291
1.21
0.46
1.6
1.1
—
—
—
0
0
135
1237
1.10
0.46
2.0
1.9
—
—
—
0
0
7
49
1.43
0.46
1.7
1.1
—
—
—
0
0
57
496
1.15
0.45
1.5
1.5
—
—
—
0
0
25
202
1.24
0.43
1.2
1.2
—
—
—
0
0
41
349
1.18
0.43
1.2
1.3
—
—
—
0
0
21
166
1.27
0.43
1.3
1.3
10.3
12.1
mmol/l
0.64
11
61
21
166
1.27
0.43
1.6
1.8
4.6
10.6
umol/l
0.91
14
106
53
461
1.15
0.43
1.4
1.9
—
—
—
0
0
31
371
0.83
0.42
3.0
4.9
364.6
349.5
umol/l
0.22
24
320
99
898
1.11
0.42
6.9
6.3
1.4
1.3
mmol/l
0.49
87
788
5
32
1.56
0.42
1.0
1.1
—
—
—
0
0
5
33
1.52
0.41
1.0
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
0.2
—
0
5
39
334
1.17
0.39
1.1
1.1
—
9.9
—
0
17
74
665
1.12
0.38
2.4
2.2
—
—
—
0
0
17
213
0.80
0.36
1.1
1.0
1.9
2.2
u/ml
—
7
74
60
671
0.89
0.36
1.5
1.6
12097.2
14976.3
e6/l
0.35
45
473
19
153
1.24
0.35
1.3
1.8
—
—
—
0
0
23
277
0.83
0.35
1.1
1.0
0.6
4.3
u/ml
4.18
13
125
6
43
1.40
0.35
1.5
1.3
50.4
75.2
%
—
6
37
19
232
0.82
0.33
1.1
1.8
12.1
11.2
%
0.33
19
232
22
182
1.21
0.33
1.1
1.3
—
—
—
0
0
16
128
1.25
0.32
1.2
1.2
—
—
—
0
0
13
101
1.29
0.31
1.4
1.4
2.8
3.1
mmol/l
0.24
13
90
7
52
1.35
0.31
7.9
2.8
—
—
—
0
0
27
230
1.18
0.31
1.1
1.4
19.9
28.8
u/l
1.14
19
186
7
53
1.32
0.30
1.1
1.1
—
—
—
0
0
159
1684
0.94
0.30
1.2
1.2
—
—
—
0
0
40
450
0.89
0.28
1.5
1.4
—
—
—
0
0
8
63
1.27
0.27
1.8
1.5
—
—
—
0
0
16
194
0.82
0.27
1.1
1.0
3.7
3.4
u/ml
—
7
69
8
64
1.25
0.27
1.0
1.0
—
—
—
0
0
8
64
1.25
0.27
1.0
1.0
—
—
—
0
0
8
64
1.25
0.27
1.0
1.0
—
—
—
0
0
8
66
1.21
0.26
1.6
1.4
—
—
—
0
0
11
138
0.80
0.25
2.5
4.0
—
—
—
0
0
12
96
1.25
0.24
1.2
2.0
25.2
103.4
ug/l
0.46
12
85
75
697
1.08
0.23
2.7
2.3
247.1
101.6
ug/min
0.69
43
422
28
246
1.14
0.23
1.9
2.1
3.2
2.1
u/field
0.44
14
90
13
106
1.23
0.23
2.7
2.5
—
—
—
0
0
66
611
1.08
0.23
4.1
3.7
28.1
28.6
mg/l
0.04
40
383
5
39
1.28
0.23
1.4
1.5
59.0
44.4
umol/l
—
5
39
68
631
1.08
0.22
2.5
3.3
398.4
757.4
u/ml
0.30
58
580
548
5600
0.97
0.21
4.2
4.4
1.0
1.0
kg/l
1.02
85
850
199
1913
1.04
0.21
1.4
1.4
—
—
—
0
0
37
409
0.90
0.21
1.1
1.1
63.6
97.3
iu/ml
—
7
84
0
11
0.00
0.21
0.0
1.1
—
0.2
—
0
5
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
0.2
—
0
5
0
12
0.00
0.21
0.0
1.0
—
0.4
—
0
5
0
12
0.00
0.21
0.0
5.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
1.0
—
0
8
0
13
0.00
0.21
0.0
1.1
—
5.1
—
0
6
28
313
0.89
0.20
1.1
1.1
0.1
1.7
u/ml
—
9
125
6
53
1.13
0.18
1.2
1.2
—
—
—
0
0
31
280
1.11
0.18
1.5
1.6
—
—
—
0
0
7
58
1.21
0.18
6.6
7.9
—
—
—
0
0
11
92
1.20
0.16
1.2
1.6
—
—
—
0
0
6
80
0.75
0.15
1.0
1.1
2113.7
1664.7
miu/ml
—
6
80
17
150
1.13
0.14
1.8
1.5
42.1
67.2
pmol/l
—
10
51
27
246
1.10
0.14
1.2
1.5
19.9
29.0
%
0.78
14
152
8
96
0.83
0.13
1.1
1.2
—
—
—
0
0
950
9410
1.01
0.12
4.5
5.1
3.0
3.6
ug/l
0.33
837
8378
11
127
0.87
0.12
1.2
1.4
—
1.4
—
0
8
861
8691
0.99
0.11
3.1
3.2
7.2
7.3
mmol/l
0.29
713
7196
25
271
0.92
0.11
1.0
1.1
0.1
1.3
u/ml
—
9
105
11
126
0.87
0.11
2.5
4.1
—
—
—
0
0
14
124
1.13
0.11
1.0
1.0
—
—
—
0
0
161
1570
1.03
0.10
1.3
1.3
—
—
—
0
0
5
44
1.14
0.10
1.4
1.5
81.3
123.4
ng/l
—
5
44
818
8116
1.01
0.09
3.9
3.0
—
—
—
0
0
253
2572
0.98
0.09
1.6
1.6
—
—
—
0
0
63
607
1.04
0.08
1.8
2.6
—
—
—
0
0
7
65
1.08
0.08
4.1
5.0
—
—
—
0
0
6
74
0.81
0.07
1.0
1.1
—
0.5
u/ml
—
0
10
14
128
1.09
0.06
2.0
1.2
198.6
137.2
nmol/l
1.43
14
128
8
95
0.84
0.06
2.1
2.4
—
—
—
0
0
23
244
0.94
0.06
1.0
1.0
5.1
1.8
u/ml
—
5
54
71
729
0.97
0.06
1.1
1.1
—
—
—
0
0
11
121
0.91
0.06
1.2
1.3
20.4
24.3
umol/l
0.19
11
115
847
8427
1.01
0.05
3.2
3.2
1575.4
307.1
mg/l
3.59
527
5318
19
179
1.06
0.05
1.1
1.4
—
—
—
0
0
35
337
1.04
0.04
1.3
1.5
69.2
60.9
%
0.61
20
208
28
292
0.96
0.04
2.2
2.0
—
—
—
0
0
88
864
1.02
0.04
1.0
1.1
—
—
—
0
0
28
270
1.04
0.03
1.2
1.2
—
—
—
0
0
19
181
1.05
0.03
2.1
2.1
2.2
2.1
ug/l
0.14
19
155
16
152
1.05
0.02
1.1
1.0
—
—
—
0
0
54
550
0.98
0.02
1.3
1.8
0.8
0.8
nmol/l
0.03
45
449
18
187
0.96
0.01
1.9
2.6
—
—
—
0
0
887
8883
1.00
0.01
3.9
4.0
13.9
8.8
mg/mmol
1.55
538
5567
19
184
1.03
0.00
1.3
1.4
1.2
1.2
promille
0.03
12
142
19
185
1.03
0.00
2.1
2.0
4.2
3.3
ug/l
0.25
19
164
46
461
1.00
0.00
1.3
1.5
—
—
—
0
0
11
114
0.96
0.00
1.0
1.1
—
—
—
0
0
23
226
1.02
0.00
1.7
1.5
0.2
0.3
nmol/l
0.23
17
169
32
322
0.99
0.00
3.4
2.6
—
—
—
0
0
237
2366
1.00
0.00
3.5
3.5
—
—
—
0
0
26
257
1.01
0.00
1.3
1.2
—
—
—
0
0
6
69
0.87
0.00
1.2
1.5
—
—
—
0
0
6
69
0.87
0.00
1.3
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
8
84
0.95
0.00
1.0
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
2.4
—
0
7
0
5
0.00
0.00
0.0
1.6
—
2984.0
—
0
5
0
5
0.00
0.00
0.0
1.6
—
1.6
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
0.00
3.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
211.2
—
0
5
59
590
1.00
0.00
1.3
1.9
2.7
4.6
iu/l
2.22
18
191
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
1270.0
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
25.8
—
0
5

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: MYELOPROF – Myeloproliferative diseases

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).