chronic myeloproliferative disorder: A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic, erythroid, megakaryocytic, and mast cell) lineages. It is primarily a neoplasm of adults. (WHO 2008)
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
1294 |
4. Check minimum number of eventsNone |
1294 |
5. Include endpointsNone |
1294 |
6. Filter based on genotype QC (FinnGen only) |
1264 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- First used in FinnGen datafreeze
- DF8
Similar endpoints
↥List of similar endpoints to
Polycythaemia vera
based on the number of shared cases.
Similar with more cases:
- Myeloproliferative diseases
- Liquid cancers, helper endpoint
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8645 | 4398 | 4141 |
| Only index persons | 6571 | 3383 | 3188 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.13 | 0.12 |
| Only index persons | 0.12 | 0.12 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 67.45 | 69.26 | 65.58 |
| Only index persons | 67.11 | 69.04 | 65.06 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1264 | 606 | 658 |
| Unadjusted period prevalence (%) | 0.26 | 0.21 | 0.30 |
| Median age at first event (years) | 65.91 | 65.39 | 66.38 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1294
- Matched controls
- 12940
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
71.1
307.7
229
39
L01XX05
ATC
hydroxycarbamide; oral
639.8
307.7
853
39
9950/3-C42.1
ICD-O-3
Polycythemia vera of bone marrow
+∞
307.7
413
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
494.6
307.7
893
58
D45
ICD-10 Finland
Polycythaemia vera
4503599627370496.0
307.7
1262
5
TPH00
NOMESCO Finland
Phlebotomy
985.4
307.7
408
6
XW000
NOMESCO Finland
Bone marrow biopsy
31.1
307.7
363
160
D75.2
ICD-10 Finland
Essential thrombocytosis
64.2
293.5
163
29
SPAT1074
SPAT
Venesection
438.7
283.0
274
8
B99
ICPC
Blood/lymph/spleen disease other
132.8
282.0
142
12
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
73.4
232.6
126
19
D75.1
ICD-10 Finland
Secondary polycythaemia
49.1
178.1
104
23
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
494.9
177.5
173
*
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
65.7
156.0
86
14
L03AB05
ATC
interferon alfa-2b; parenteral
1259.8
119.8
115
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
37.3
118.6
74
21
M04AA01
ATC
allopurinol; systemic
4.1
108.1
381
1187
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.4
100.5
302
832
9962/3-C42.1
ICD-O-3
Essential thrombocythemia of bone marrow
57.4
97.3
55
10
L01XX35
ATC
anagrelide; oral
324.5
90.0
90
*
B28
ICPC
Limited function/disability (B)
25.1
84.7
60
25
WW500
NOMESCO Finland
Blood transfusion
9.8
78.3
93
101
174
Kela drug reimbursment
Ruxolitinib
+∞
77.9
74
*
212
Kela drug reimbursment
Gout
9.3
76.8
95
109
L03AB04
ATC
interferon alfa-2a; parenteral
400.3
76.6
76
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
75.8
72
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
771.3
75.0
73
*
374
Kela drug reimbursment
Ruxolitinib
+∞
73.6
70
*
B04
ICPC
Blood symptom/complaint
27.3
72.9
50
19
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
72.6
69
*
TPH00, ,
SPAT
253.9
71.1
72
*
L01EJ01
ATC
ruxolitinib; oral
+∞
70.5
67
*
H02AB02
ATC
dexamethasone; systemic
11.0
67.0
73
70
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
239.0
66.9
68
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.0
59.4
186
517
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.0
57.3
106
190
9960/3-C42.1
ICD-O-3
Myeloproliferative neoplasm, NOS, of bone marrow
561.0
55.0
54
*
115
Kela drug reimbursment
Breast cancer
+∞
50.3
48
*
B74
ICPC
Malignant neoplasm blood other
249.0
47.3
48
*
PJA12
NOMESCO Finland
Sentinel node biopsy
249.0
47.3
48
*
130
Kela drug reimbursment
Malignant tumour
+∞
47.2
45
*
A04AA01
ATC
ondansetron; systemic, rectal
6.3
43.2
75
126
L01XE18
ATC
[U] ruxolitinib
+∞
43.0
41
*
116
Kela drug reimbursment
Prostate cancer
+∞
43.0
41
*
D75.0
ICD-10 Finland
Familial erythrocytosis
81.3
42.2
47
6
B01AB05
ATC
enoxaparin; parenteral
2.3
41.8
465
2541
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
39.8
38
*
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
126.9
34.9
37
*
XX7BT
NOMESCO Finland
Radioactive phosphorus therapy
+∞
34.5
33
*
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
12.0
33.5
34
29
L57.0
ICD-10 Finland
Actinic keratosis
2.9
32.9
167
621
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
12.6
32.5
32
26
XX3DW
NOMESCO Finland
Time consuming IT work
3.7
31.5
103
292
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.2
31.3
135
457
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
52.8
30.5
36
7
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
30.3
29
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
30.3
29
*
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
38.0
29.4
37
10
2384A
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Polycythaemia vera
+∞
29.3
28
*
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
6.9
29.0
45
67
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
28.2
27
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
28.2
27
*
A03FA01
ATC
metoclopramide; systemic, rectal
2.5
27.7
191
828
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
27.5
654
4534
L02BG04
ATC
letrozole; oral
32.7
26.9
35
11
JN4AD
NOMESCO Finland
Body CT examination
3.2
26.9
110
360
WZC00
NOMESCO Finland
Treatment plan or consultation
2.0
26.9
374
2163
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
34.9
26.6
34
10
WF002
NOMESCO Finland
Radical radiotherapy
41.0
25.9
32
8
Z51.5
ICD-10 Finland
Palliative care
3.6
25.7
88
257
ZX120
NOMESCO Finland
Intravenous
3.0
25.2
121
435
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.5
25.1
183
813
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
4.4
24.2
62
147
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.8
23.9
128
488
A04AA02
ATC
granisetron; systemic, transdermal
88.5
23.7
26
*
JN4BD
NOMESCO Finland
Extensive body CT
3.3
23.6
92
292
ZZR00
NOMESCO Finland
Flap of skin
19.9
23.5
35
18
R50.9
ICD-10 Finland
Fever, unspecified
2.3
23.0
199
951
HA1AA
NOMESCO Finland
X-ray mammography
4.4
22.7
58
137
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
122.2
22.6
24
*
ZX112
NOMESCO Finland
Subcutaneous
9.2
22.1
27
30
B03XA02
ATC
darbepoetin alfa; parenteral
5.5
21.9
43
81
L03AA04, ,
ATC
+∞
21.9
21
*
B75
ICPC
Neoplasm blood benign/unspecified
+∞
21.9
21
*
HAC20
NOMESCO Finland
Total mastectomy
223.6
21.7
22
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
4.9
21.4
47
98
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
21.2
416
2660
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
20.9
20
*
L01AB01
ATC
busulfan; systemic
+∞
20.9
20
*
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
20.9
20
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
111.8
20.6
22
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.0
20.1
95
338
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
19.8
19
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
203.0
19.6
20
*
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
46.8
19.2
23
5
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.2
19.2
77
249
JN4CD
NOMESCO Finland
Very extensive body CT
5.6
18.9
36
66
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
18.8
167
804
C50.99
ICD-10 Finland
Breast, unspecified
+∞
18.8
18
*
20899
ICD-8 Finland
Polycythaemia vera
+∞
18.8
18
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
18.8
18
*
L03AA13
ATC
pegfilgrastim; parenteral
71.0
18.7
21
*
Y77
ICPC
Malignant neoplasm prostate
192.7
18.6
19
*
L02AE02
ATC
leuprorelin; implant, parenteral
27.1
17.8
24
9
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
17.7
17
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
17.7
17
*
HAB40
NOMESCO Finland
Wedge excision of mammary gland
14.8
17.7
29
20
C90.0
ICD-10 Finland
Multiple myeloma
182.4
17.6
18
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
182.4
17.6
18
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
42.6
17.3
21
5
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.6
17.3
102
408
D75.8
ICD-10 Finland
Other specified diseases of blood and blood-forming organs
50.7
17.0
20
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.7
16.9
91
347
B01AA03
ATC
warfarin; systemic
1.8
16.8
347
2227
PH_2
NOMESCO Finland
Other procedures on veins
+∞
16.7
16
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
16.7
16
*
Z3231
NOMESCO Finland
Registered nurse
1.8
16.5
336
2146
B01AB10
ATC
tinzaparin; parenteral
2.5
16.5
110
467
TQW99
NOMESCO Finland
Other minor procedure on skin
3.1
16.5
69
229
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
40.6
16.4
20
5
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
13.0
16.2
28
22
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
48.1
16.0
19
*
S97
ICPC
Chronic ulcer skin
2.4
15.9
115
506
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.1
15.9
69
234
D73.5
ICD-10 Finland
Infarction of spleen
60.8
15.8
18
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.6
15.8
96
390
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
+∞
15.7
15
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
15.7
15
*
I81
ICD-10 Finland
Portal vein thrombosis
17.4
15.6
24
14
R04.0
ICD-10 Finland
Epistaxis
2.3
15.5
129
603
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
4.4
15.5
39
91
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
3.3
15.5
60
190
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.3
15.1
117
531
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
14.9
272
1676
N02AA05
ATC
oxycodone; systemic
1.9
14.9
214
1226
ZX090
NOMESCO Finland
Other technic of radiotherapy
32.1
14.8
19
6
XQ848
NOMESCO Finland
Dermatological photography
3.8
14.7
45
122
L02BG03
ATC
anastrozole; oral
+∞
14.6
14
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
14.6
14
*
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
+∞
14.6
14
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
14.6
14
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
27.5
14.3
19
7
R71
ICD-10 Finland
Abnormality of red blood cells
22.5
14.2
20
9
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.2
14.0
37
90
ZY010
NOMESCO Finland
Hospital outpatient
3.1
13.9
58
192
A46
ICD-10 Finland
Erysipelas
1.8
13.8
215
1262
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
76.0
13.6
15
*
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
+∞
13.6
13
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
13.6
13
*
L03AA02
ATC
filgrastim; parenteral
26.0
13.4
18
7
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
4.1
13.3
36
89
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.0
13.3
165
897
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
50.5
12.9
15
*
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
5.8
12.8
23
40
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
12.5
12
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
12.5
12
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
12.5
12
*
L02BB03
ATC
bicalutamide; oral
+∞
12.5
12
*
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
+∞
12.5
12
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
12.5
12
*
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
131.2
12.5
13
*
D47.0
ICD-10 Finland
Histiocytic and mast cell tumours of uncertain and unknown behaviour
131.2
12.5
13
*
K99
ICPC
Cardiovascular disease other
2.9
12.5
58
205
WZC30
NOMESCO Finland
Teaching
2.0
12.3
150
810
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.6
12.3
72
287
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
4.3
12.0
31
74
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
3.6
12.0
40
115
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
4.4
12.0
30
70
C03CA01
ATC
furosemide; systemic
1.5
11.8
474
3537
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
65.6
11.6
13
*
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
23.1
11.6
16
7
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
4.4
11.5
28
64
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
11.5
11
*
8380/3-C54.1
ICD-O-3
Endometrioid adenocarcinoma, NOS, of endometrium
+∞
11.5
11
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
11.5
11
*
KEC00
NOMESCO Finland
Retropubic radical prostatectomy
+∞
11.5
11
*
X76
ICPC
Malignant neoplasm breast female
121.1
11.4
12
*
C50
ICD-10 Finland
Malignant neoplasm of breast
121.1
11.4
12
*
ZXC50
NOMESCO Finland
Cryotherapy
3.4
11.4
40
119
G04BE03
ATC
sildenafil; oral
11.9
11.3
20
17
L71.9
ICD-10 Finland
Rosacea, unspecified
3.4
11.3
40
120
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
11.3
188
1122
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
11.1
131
700
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
11.3
11.1
20
18
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
10.9
285
1920
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
10.8
229
1461
J01DB01
ATC
cefalexin; oral
1.6
10.8
974
8539
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
4.5
10.5
25
56
WF004
NOMESCO Finland
Palliative radiotherapy
110.9
10.4
11
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
10.4
10
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
10.4
10
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
10.4
10
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
10.4
10
*
K29
ICPC
Cardiovascular sympt/complt other
2.3
10.3
77
344
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
18.9
10.3
15
8
C03DA01
ATC
spironolactone; oral
1.7
10.0
190
1176
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.6
10.0
57
225
L02BA01
ATC
tamoxifen; oral
40.4
10.0
12
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
26.2
9.8
13
5
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
26.2
9.8
13
5
127
Kela drug reimbursment
Transplant complication
5.1
9.6
20
40
B01AB04
ATC
dalteparin; parenteral
2.5
9.6
62
260
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
100.8
9.4
10
*
8070/3-C44.3
ICD-O-3
Squamous cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
9.4
9
*
L01BC06
ATC
capecitabine; oral
+∞
9.4
9
*
128
Kela drug reimbursment
Cancers of female genital organs
+∞
9.4
9
*
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
+∞
9.4
9
*
8090/3-C44.4
ICD-O-3
Basal cell carcinoma, NOS, of skin of scalp and neck
+∞
9.4
9
*
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
+∞
9.4
9
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
9.4
9
*
D68.8
ICD-10 Finland
Other specified coagulation defects
4.9
9.3
20
41
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
10.7
9.3
17
16
UJF32
NOMESCO Finland
Coloscopy
1.5
9.2
309
2198
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
9.1
295
2078
D06BB10
ATC
imiquimod; topical
2.4
9.1
61
260
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
3.5
9.1
30
86
ZXC20
NOMESCO Finland
Use of chemical agents
3.8
9.1
27
72
R60.0
ICD-10 Finland
Localized oedema
1.7
9.1
165
1008
A79
ICPC
Malignancy NOS
37.0
9.0
11
*
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
3.6
9.0
29
82
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
3.4
8.9
31
92
I82.0
ICD-10 Finland
Budd-Chiari syndrome
50.3
8.7
10
*
K93
ICPC
Pulmonary embolism
4.1
8.5
23
57
B86
ICPC
OTHER HAEMATOLOGICAL ABNORMALITY
90.6
8.4
9
*
D58.2
ICD-10 Finland
Other haemoglobinopathies
90.6
8.4
9
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
90.6
8.4
9
*
L29.8
ICD-10 Finland
Other pruritus
3.8
8.4
25
67
XKD00
NOMESCO Finland
Uroflowmetry
1.7
8.4
179
1142
8090/3-C44.1
ICD-O-3
Basal cell carcinoma, NOS, of eyelid
+∞
8.3
8
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
8.3
8
*
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
+∞
8.3
8
*
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
+∞
8.3
8
*
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
+∞
8.3
8
*
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
+∞
8.3
8
*
SPAT1088
SPAT
Blood transfusion
10.8
8.3
15
14
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
8.2
191
1245
UJF30
NOMESCO Finland
Ileoscopy through colon
1.8
8.1
118
674
Z03.1
ICD-10 Finland
Observation for suspected malignant neoplasm
4.6
8.1
19
42
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.2
8.1
31
98
M10.9
ICD-10 Finland
Gout, unspecified
1.9
8.1
106
586
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
8.1
237
1630
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
4.1
8.1
22
55
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
33.6
8.1
10
*
KAC11
NOMESCO Finland
Total nephrectomy with capsule, transcutaneous
33.6
8.1
10
*
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
33.6
8.1
10
*
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.8
8.1
38
136
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
22.2
8.0
11
5
A05AA02
ATC
ursodeoxycholic acid; oral
4.2
8.0
21
51
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
3.7
7.9
24
65
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
4.7
7.9
18
39
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
3.2
7.8
30
95
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
3.0
7.8
33
111
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
10.9
7.8
14
13
D73.1
ICD-10 Finland
Hypersplenism
45.3
7.7
9
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.8
7.6
108
614
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
10.1
7.5
14
14
ZXE00
NOMESCO Finland
One hour or less
1.4
7.5
412
3204
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.8
7.5
112
646
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
3.9
7.4
21
54
C44.22
ICD-10 Finland
Spinocellular carcinoma of the skin of the outer ear and the outer ear canal
80.5
7.4
8
*
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
80.5
7.4
8
*
B59
ICPC
Blood and Immunity, Other therap proced/minor surg NEC
80.5
7.4
8
*
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
80.5
7.4
8
*
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
80.5
7.4
8
*
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.6
7.4
186
1233
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
+∞
7.3
7
*
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
+∞
7.3
7
*
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
+∞
7.3
7
*
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
+∞
7.3
7
*
C44.39
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face other or unspecified histology
+∞
7.3
7
*
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
+∞
7.3
7
*
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
7.3
7
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
7.3
7
*
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
+∞
7.3
7
*
B01AC14
ATC
[U] anagrelide
+∞
7.3
7
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
7.3
312
2318
WX402
NOMESCO Finland
General anaesthesia
1.6
7.3
173
1133
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
2.6
7.2
42
168
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
2.5
7.2
43
174
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
7.2
389
3014
S18
ICPC
Laceration/cut
1.4
7.2
519
4224
N17.8
ICD-10 Finland
Other acute renal failure
4.0
7.2
20
51
ZX070
NOMESCO Finland
Intensity modified radiotherapy
30.2
7.2
9
*
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
30.2
7.2
9
*
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
8.0
7.1
15
19
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.8
7.1
21
56
H02AB06
ATC
prednisolone; systemic
1.4
7.1
551
4535
T14.5
ICD-10 Finland
Injury of blood vessel(s) of unspecified body region
5.7
7.1
19
34
A02BC02
ATC
pantoprazole; systemic
1.4
7.0
793
6923
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
3.4
7.0
24
71
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.6
7.0
170
1119
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.9
6.9
84
454
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.6
6.9
126
1972
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
3.6
6.9
22
62
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
6.9
131
810
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
6.8
131
813
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
2.9
6.8
30
104
S77
ICPC
Malignant neoplasm of skin
22.6
6.7
9
*
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
22.6
6.7
9
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.9
6.7
30
105
A07AA02
ATC
nystatin; oral
2.0
6.6
73
382
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
6.5
111
665
E83.1
ICD-10 Finland
Disorders of iron metabolism
10.1
6.5
12
12
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.1
6.5
58
280
B03XA01
ATC
erythropoietin; parenteral
6.2
6.5
16
26
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
70.2
6.4
7
*
D46.2
ICD-10 Finland
Refractory anaemia with excess of blasts [RAEB]
70.2
6.4
7
*
N02AX02
ATC
tramadol; systemic, rectal
1.4
6.4
494
4042
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
14.4
6.4
10
7
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
2.2
6.4
51
236
ZZA00
NOMESCO Finland
Split skin graft
2.8
6.3
31
114
L02AE03
ATC
goserelin; implant
18.1
6.3
9
5
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
6.3
151
991
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
+∞
6.3
6
*
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
6.3
6
*
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
+∞
6.3
6
*
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
+∞
6.3
6
*
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
+∞
6.3
6
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
6.3
6
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
6.3
6
*
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
+∞
6.3
6
*
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
+∞
6.3
6
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
6.3
6
*
8140/3-C34.1
ICD-O-3
Adenocarcinoma, NOS, of upper lobe, lung
+∞
6.3
6
*
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
+∞
6.3
6
*
YJ1AD
NOMESCO Finland
CT examination of abdomen for dose design of radiotherapy
+∞
6.3
6
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
6.3
6
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
6.3
6
*
YJ2VG
NOMESCO Finland
MRI examination of pelvis with high intensity magnet for dose design of radiotherapy
+∞
6.3
6
*
C34.99
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary other or unspecified histology
+∞
6.3
6
*
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
+∞
6.3
6
*
D69.1
ICD-10 Finland
Qualitative platelet defects
26.8
6.2
8
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
6.1
83
465
PFH63
NOMESCO Finland
Bypass from femoral or popliteal artery to distal posterior tibial artery
12.6
6.1
10
8
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.8
6.0
91
527
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
3.2
6.0
23
73
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
2.1
6.0
54
262
L03.9
ICD-10 Finland
Cellulitis, unspecified
2.8
6.0
28
100
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
258
120
26.61
307.65
1.5
1.4
—
—
—
0
0
847
987
22.95
307.65
9.9
2.5
290.74
235.78
u/l
16.85
835
922
472
171
42.88
307.65
1.3
1.2
17.68
23.36
u/l
0.41
357
151
403
108
53.74
307.65
1.1
1.0
—
—
—
0
0
448
919
6.93
223.75
3.8
2.1
87.85
67.57
e9/l
20.74
328
707
521
1251
6.30
220.37
4.1
2.0
1.96
1.76
%
4.46
465
1089
787
2742
5.77
216.28
5.1
2.4
2216.27
7754.52
umol/l
4.09
745
2339
987
4276
6.51
206.04
17.0
5.4
1.22
0.67
%
41.95
963
3928
997
4416
6.48
200.87
17.3
5.4
2.66
2.98
%
5.68
973
4065
995
4437
6.38
197.66
18.5
5.7
7.58
8.82
%
24.01
971
4085
351
640
7.15
194.82
10.4
3.6
0.76
0.60
%
0.63
203
162
357
665
7.03
194.02
10.2
3.7
0.16
0.06
%
2.19
199
150
997
4515
6.26
192.50
17.9
5.5
21.60
26.95
%
42.30
972
4179
987
4475
6.08
188.95
16.2
5.4
64.92
57.90
%
52.75
960
4138
1020
4756
6.41
188.70
15.3
5.2
0.09
0.04
e9/l
52.89
945
4053
1031
4919
6.39
183.44
17.1
5.4
0.25
0.20
e9/l
3.58
964
4250
1022
4843
6.28
183.25
15.8
5.3
1.99
1.84
e9/l
0.34
964
4214
145
94
17.25
170.08
8.4
2.7
1.31
1.26
%
0.04
123
78
1044
5284
6.05
165.43
22.4
6.0
6.41
4.33
e9/l
26.97
978
4520
932
4830
4.32
128.82
10.1
3.7
13.26
12.02
umol/l
2.76
914
4497
425
1358
4.17
117.47
2.7
2.5
18.56
22.93
%
6.11
368
1140
430
1459
3.92
108.01
2.6
2.4
2.57
2.29
g/l
17.23
407
1343
94
68
14.83
103.23
9.2
2.9
69.78
54.80
%
5.88
73
55
446
1599
3.73
102.54
2.7
2.4
11.16
12.95
umol/l
4.63
423
1474
152
221
7.66
101.46
2.9
2.2
3.10
3.45
g/l
2.08
144
204
707
3983
2.71
66.91
3.6
2.7
115.52
133.49
ug/l
0.96
664
3608
120
232
5.60
59.91
2.6
2.0
91.78
87.37
%
1.21
107
225
96
151
6.79
59.07
4.8
3.2
65.59
58.28
%
3.97
96
151
1060
7626
3.16
57.83
16.2
5.3
88.46
76.21
u/l
11.61
1036
7015
174
486
3.98
55.07
1.8
1.5
0.98
1.54
g/l
14.71
153
422
802
5208
2.42
50.53
8.1
5.6
1.21
1.22
mmol/l
0.41
680
4427
87
148
6.23
49.51
3.6
3.1
5.94
4.39
e9/l
3.06
87
148
103
235
4.68
42.26
2.0
1.5
—
—
—
0
0
94
208
4.79
40.00
3.1
2.1
171.04
199.56
%
2.18
88
194
72
131
5.76
38.16
5.5
5.8
505.67
443.30
iu/ml
—
6
20
661
4289
2.11
37.27
6.4
3.7
35.58
35.41
g/l
0.31
626
3914
35
27
13.30
36.67
6.9
2.0
—
—
—
0
0
704
4715
2.08
36.02
7.3
5.3
1.22
1.21
mmol/l
0.87
646
4184
235
1002
2.64
35.85
5.1
2.1
7.48
8.32
umol/l
0.42
212
853
467
2693
2.15
35.53
2.4
2.2
7.90
2.95
mg/l
27.00
401
2250
413
2336
2.13
32.50
5.6
3.5
77.42
85.30
%
7.27
391
2268
378
2096
2.13
31.10
2.1
1.6
1.18
1.35
mg/l
0.59
295
1619
833
6147
2.00
30.11
5.7
4.5
6.65
6.87
mmol/l
2.54
803
5749
283
1503
2.13
25.41
3.7
2.5
0.82
0.82
mmol/l
0.07
264
1366
292
1592
2.08
24.35
3.0
1.9
33.19
29.99
s
7.83
273
1529
697
5106
1.79
22.92
26.9
18.3
1.49
1.38
inr
2.21
234
1436
253
1349
2.09
22.20
5.3
4.8
1.08
1.02
mmol/l
2.27
238
1226
128
520
2.62
21.07
2.8
1.4
20.46
2.79
ug/l
0.53
102
381
163
749
2.35
20.58
2.0
2.0
0.20
0.20
g/l
0.19
152
670
30
48
6.37
18.06
1.1
1.3
—
—
—
0
0
30
48
6.37
18.06
1.1
1.3
—
—
—
0
0
23
7
33.41
17.99
1.1
1.0
—
—
—
0
0
51
131
4.01
17.91
2.1
1.5
—
—
—
0
0
137
619
2.36
17.91
2.3
2.2
10.69
10.93
g/l
0.21
121
561
63
191
3.42
17.40
2.0
1.5
—
—
—
0
0
84
305
2.88
17.13
2.6
1.5
1.35
1.23
ratio
—
7
24
85
316
2.81
16.60
2.7
1.5
30.19
35.79
mg/l
0.83
73
251
169
860
2.11
16.49
2.8
1.6
66.40
66.96
g/l
0.45
160
762
84
316
2.77
16.04
2.7
1.5
82.87
44.62
mg/l
0.44
71
251
286
1758
1.80
15.94
2.1
1.8
—
—
—
0
0
914
7610
1.68
15.78
5.1
4.2
8.46
12.82
mm/h
19.48
863
6968
59
183
3.33
15.73
2.2
1.5
—
—
—
0
0
98
406
2.53
15.45
2.3
1.7
1.16
1.60
ug/l
0.36
84
354
568
4241
1.60
15.02
4.4
2.3
—
—
—
0
0
170
900
2.02
14.86
6.2
6.1
10.05
10.84
mmol/l
0.75
160
844
325
2144
1.69
13.88
5.0
2.1
—
—
—
0
0
46
132
3.58
13.84
2.2
1.5
—
—
—
0
0
46
132
3.58
13.84
2.2
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
80
321
2.59
13.48
4.6
2.6
0.36
0.35
u/ml
0.06
49
192
60
209
2.96
13.21
1.2
1.3
—
—
—
0
0
614
4767
1.55
13.11
2.3
2.1
88.08
94.22
pmol/l
2.89
401
2350
151
804
1.99
12.94
3.0
2.9
1.21
1.23
mmol/l
2.12
125
667
395
2807
1.59
12.29
1.8
1.6
18.55
20.80
nmol/l
2.12
353
2314
454
3334
1.56
12.22
3.3
2.1
2.34
2.36
mmol/l
1.73
394
2739
418
3021
1.57
12.04
3.7
3.1
42.41
78.34
e6/l
0.73
331
2335
426
3145
1.53
10.93
3.0
2.3
53.29
60.11
u/l
2.24
391
2870
37
109
3.46
10.74
1.1
1.1
—
—
—
0
0
28
68
4.19
10.64
2.3
1.2
—
—
—
0
0
28
68
4.19
10.64
2.3
1.2
—
—
—
0
0
28
68
4.19
10.64
2.3
1.2
—
—
—
0
0
477
3628
1.50
10.53
3.8
3.1
—
—
—
0
0
14
6
23.57
10.25
3.4
1.0
44.22
14.67
u/ml
—
14
6
396
2918
1.51
10.10
4.7
2.6
32.45
33.98
u/l
0.42
378
2755
128
701
1.92
10.07
2.2
1.5
—
—
—
0
0
36
109
3.37
10.04
1.4
1.4
—
—
—
0
0
727
6048
1.46
9.97
3.9
3.0
62.28
49.33
u/l
2.99
687
5509
377
2764
1.51
9.79
3.6
3.0
0.59
0.40
e6/l
0.46
297
2122
88
426
2.14
9.73
2.4
1.7
—
—
—
0
0
475
3659
1.47
9.63
3.6
3.0
2015.35
1594.64
ng/l
1.10
416
3136
460
3523
1.47
9.60
4.3
3.6
137.56
125.71
e6/l
0.09
347
2518
22
32
6.97
9.33
2.5
1.1
—
—
—
0
0
22
32
6.97
9.33
2.5
1.1
—
—
—
0
0
29
80
3.69
9.30
2.4
1.3
—
—
—
0
0
1099
10022
1.64
9.17
27.9
13.7
19.50
24.17
mg/l
6.55
968
7846
20
42
4.82
9.08
1.6
2.6
1229.80
1039.07
u/ml
0.16
20
42
18
20
9.11
9.04
1.4
1.1
67.30
87.22
%
—
10
9
18
20
9.11
9.04
1.4
1.1
64.00
82.11
%
—
10
9
41
144
2.91
8.96
1.5
1.4
—
—
—
0
0
25
64
3.96
8.89
1.3
1.2
—
—
—
0
0
40
142
2.87
8.59
1.2
1.1
—
—
—
0
0
301
2158
1.51
8.53
2.9
2.4
3.79
5.30
e6/l
2.17
273
1930
29
85
3.47
8.53
1.8
1.6
—
—
—
0
0
14
11
12.85
8.38
1.1
1.3
—
—
—
0
0
80
397
2.08
8.32
1.9
1.6
—
—
—
0
0
29
88
3.35
8.10
2.4
1.3
—
—
—
0
0
17
21
8.19
8.09
2.9
1.1
—
—
—
0
0
17
21
8.19
8.09
2.9
1.1
—
—
—
0
0
17
21
8.19
8.09
2.9
1.1
—
—
—
0
0
34
114
3.04
8.08
1.1
1.1
2.83
1.56
u/ml
0.64
12
32
11
5
22.17
8.02
1.5
3.8
—
—
—
0
0
542
4389
1.40
7.95
4.6
4.0
55.50
62.89
ng/l
0.13
429
3261
48
201
2.44
7.49
2.4
1.8
99.59
39.43
u/ml
0.33
37
157
19
45
4.27
7.49
1.4
2.2
30.14
46.74
%
—
7
26
117
684
1.78
7.49
4.2
3.5
5.28
5.18
kpa
0.49
107
645
32
109
2.98
7.42
1.1
1.2
3.17
5.68
u/ml
0.57
18
50
518
4202
1.39
7.36
2.4
2.3
76.64
78.95
nmol/l
1.08
466
3616
76
390
2.01
7.25
2.7
1.5
3.10
3.02
g/l
0.27
68
333
18
42
4.33
7.23
2.6
1.8
2.19
3.56
nmol/l
1.40
18
42
81
427
1.96
7.16
2.7
1.4
3.25
3.73
g/l
3.26
73
370
81
427
1.96
7.16
2.7
1.4
6.76
7.59
g/l
4.95
74
369
81
427
1.96
7.16
2.7
1.4
—
—
—
0
0
138
858
1.68
7.10
2.1
1.8
411.91
363.05
nmol/l
1.55
129
761
69
345
2.06
7.07
2.9
1.4
1.13
0.53
g/l
0.73
59
290
160
1035
1.62
7.05
4.1
3.2
—
—
—
0
0
63
305
2.12
7.02
2.9
1.4
0.00
0.02
g/l
0.59
57
274
77
402
1.97
7.00
2.8
1.4
10.73
10.67
g/l
0.04
69
344
110
646
1.77
6.94
4.3
3.4
2.38
1.83
mmol/l
0.61
79
466
113
683
1.72
6.45
1.7
1.6
—
—
—
0
0
21
60
3.54
6.45
2.0
1.7
—
—
—
0
0
770
6741
1.35
6.38
5.4
4.6
60.88
2460.47
e6/l
—
8
104
32
120
2.71
6.28
1.3
1.3
—
—
—
0
0
936
8460
1.38
6.25
39.6
16.0
18.10
15.24
%
31.26
929
8254
58
286
2.08
6.20
3.0
1.4
0.00
0.00
g/l
-0.00
53
259
37
151
2.49
6.14
1.1
1.3
—
—
—
0
0
30
110
2.77
6.14
1.4
1.4
—
—
—
0
0
590
4984
1.34
6.12
5.9
5.1
0.00
0.00
estimate
-0.00
158
819
132
844
1.63
6.10
3.6
2.4
53.33
63.04
ml/min/173m2
3.54
86
338
590
4988
1.34
6.07
4.3
3.8
0.00
0.00
estimate
0.99
175
901
34
134
2.58
6.06
1.2
1.1
373.20
272.03
u/ml
0.75
20
70
58
290
2.05
5.98
3.0
1.4
0.00
0.00
g/l
-0.00
53
260
30
113
2.69
5.85
1.7
1.5
—
—
—
0
0
261
1946
1.43
5.85
3.5
2.2
2.45
2.45
mmol/l
0.21
230
1655
23
75
3.10
5.78
1.9
2.2
—
—
—
0
0
593
5044
1.32
5.74
4.3
3.8
0.00
0.01
estimate
0.80
160
802
32
127
2.56
5.65
1.5
1.3
—
—
—
0
0
41
183
2.28
5.62
1.4
1.5
—
—
—
0
0
35
146
2.44
5.58
1.5
1.2
—
17.62
—
0
5
1028
9500
1.40
5.54
26.9
12.7
73.76
74.91
ml/min/173m2
1.06
915
7648
63
335
1.93
5.49
2.9
1.4
38.72
37.53
g/l
0.77
56
278
178
1252
1.49
5.39
2.0
1.8
—
—
—
0
0
305
2366
1.38
5.39
1.8
1.8
1030.30
1172.05
nmol/l
1.98
239
1766
174
1224
1.49
5.26
5.8
7.1
4.95
5.09
kpa
1.05
164
1168
174
1224
1.49
5.26
5.8
7.1
10.84
11.36
kpa
0.77
164
1168
223
1646
1.43
5.25
1.5
1.3
2.53
2.67
g/l
0.54
146
924
174
1228
1.48
5.18
6.0
7.1
0.96
1.32
mmol/l
0.45
132
972
44
210
2.13
5.16
2.8
2.4
17.35
16.34
%
0.45
21
109
82
489
1.72
4.96
2.7
2.9
4.33
4.43
pmol/l
0.56
69
416
46
227
2.06
4.96
3.2
2.8
7.35
7.94
kpa
1.65
46
219
459
3829
1.31
4.90
4.5
4.0
—
—
—
0
0
1043
9726
1.37
4.80
5.2
4.2
1.32
1.30
mmol/l
0.63
988
8725
60
330
1.86
4.76
2.9
3.1
—
—
—
0
0
15
34
4.45
4.75
1.2
1.3
—
—
—
0
0
57
311
1.87
4.64
1.4
1.2
—
—
—
0
0
11
18
6.15
4.60
1.3
1.2
—
—
—
0
0
174
1258
1.44
4.57
1.9
1.8
—
—
—
0
0
14
31
4.55
4.56
34.6
26.0
123.50
146.00
ug/l
0.56
14
25
52
277
1.91
4.55
3.3
3.1
25.44
24.99
mmol/l
0.21
52
272
13
27
4.85
4.50
1.5
1.5
—
—
—
0
0
10
15
6.71
4.47
1.1
1.3
—
—
—
0
0
84
523
1.65
4.36
4.6
8.8
24.11
24.41
mmol/l
0.34
84
505
18
61
2.98
4.29
1.5
1.5
—
—
—
0
0
7
6
11.72
4.28
1.1
1.2
—
—
—
0
0
7
6
11.72
4.28
1.0
1.7
—
—
—
0
0
123
842
1.51
4.26
2.2
2.2
33.39
38.50
u/l
0.39
101
688
20
73
2.77
4.19
1.1
1.1
—
—
—
0
0
332
2700
1.31
4.16
4.5
4.1
0.00
0.00
estimate
0.50
154
794
50
273
1.86
4.09
1.4
1.5
1.11
0.12
iu/ml
—
9
62
152
1095
1.44
4.08
6.3
7.4
94.21
95.00
%
0.51
147
1057
7
7
10.05
4.01
1.3
1.1
—
—
—
0
0
30
139
2.19
3.85
1.1
1.3
0.65
0.69
nmol/l
0.28
30
130
24
101
2.40
3.83
1.8
1.6
—
—
—
0
0
24
101
2.40
3.83
1.8
1.6
—
—
—
0
0
7
8
8.79
3.77
1.1
1.0
—
—
—
0
0
12
29
4.17
3.70
2.6
2.9
—
—
—
0
0
27
122
2.24
3.69
1.0
1.1
—
—
—
0
0
146
1074
1.41
3.50
4.1
3.0
1.70
2.09
mmol/l
0.71
118
897
67
418
1.64
3.50
4.9
3.8
24.43
24.85
mmol/l
0.52
60
377
9
18
5.03
3.37
5.4
1.2
—
—
—
0
0
23
101
2.30
3.37
1.1
1.6
21145.56
91320.60
e6/l
—
9
57
121
867
1.44
3.36
3.4
3.6
89.04
92.71
ng/l
0.19
104
738
22
95
2.34
3.35
2.5
2.5
—
—
—
0
0
203
1587
1.33
3.33
3.5
2.8
1.46
2.73
e6/l
2.87
116
865
14
48
2.94
3.30
1.0
1.1
—
—
—
0
0
44
249
1.79
3.27
2.3
2.0
13.56
12.02
mg/l
0.47
38
227
47
272
1.76
3.25
1.3
1.6
1.09
1.15
g/l
0.88
42
258
40
221
1.84
3.22
1.4
1.3
—
—
—
0
0
995
9371
1.27
3.20
5.3
4.7
2.10
2.13
mu/l
0.09
944
8427
46
266
1.76
3.19
1.3
1.6
0.22
0.23
g/l
0.12
41
255
11
29
3.82
3.19
1.1
1.3
—
—
—
0
0
7
11
6.39
3.18
2.7
4.0
—
—
—
0
0
56
346
1.65
3.07
1.2
1.2
0.16
0.85
u/ml
—
5
31
24
113
2.15
3.01
1.0
1.6
2864.08
1638.91
e6/l
0.39
12
82
25
120
2.10
2.99
1.1
1.6
31.67
26.39
g/l
1.18
20
107
5
5
10.03
2.98
1.0
1.4
—
—
—
0
0
1119
10724
1.32
2.96
29.7
16.8
139.46
139.75
mmol/l
3.51
1105
10414
215
1724
1.30
2.94
3.3
2.6
0.77
1.49
e6/l
2.12
126
998
828
7696
1.21
2.76
4.2
3.8
15.05
15.01
pmol/l
0.19
766
6878
1053
10035
1.26
2.75
5.7
4.8
1.25
1.45
mmol/l
43.64
1000
9094
5
6
8.36
2.75
1.4
1.5
2.10
2.17
%
—
5
6
13
48
2.73
2.72
1.0
1.1
97.38
85.55
u/l
0.23
13
42
13
49
2.67
2.62
1.0
1.1
33.23
24.23
u/l
0.28
13
42
12
41
2.94
2.62
1.4
1.4
—
—
—
0
0
12
41
2.94
2.62
1.4
1.4
—
—
—
0
0
406
3543
1.21
2.61
2.2
2.2
151.99
229.86
u/l
1.69
375
3304
7
15
4.69
2.60
1.7
1.0
—
—
—
0
0
7
15
4.69
2.60
1.7
1.0
—
—
—
0
0
1061
10140
1.26
2.58
5.7
4.8
4.00
4.53
mmol/l
55.83
1017
9256
9
25
3.62
2.57
1.6
2.2
1.16
1.21
mmol/l
—
9
25
565
5090
1.20
2.57
2.5
2.4
—
—
—
0
0
1118
10753
1.29
2.57
31.5
16.9
4.04
4.00
mmol/l
5.58
1104
10422
270
2263
1.24
2.55
3.7
4.1
138.08
483.74
ng/l
3.66
212
1907
87
622
1.43
2.50
1.8
1.5
—
—
—
0
0
13
51
2.56
2.44
1.4
1.3
—
—
—
0
0
68
467
1.48
2.42
5.2
5.4
1.87
1.62
%
1.06
62
446
11
38
2.91
2.41
2.0
1.4
13.60
11.27
ug/l
0.12
11
32
23
117
1.98
2.41
2.3
1.2
—
—
—
0
0
23
117
1.98
2.41
2.3
1.2
—
—
—
0
0
33
190
1.76
2.39
1.5
1.6
—
—
—
0
0
84
604
1.42
2.36
3.5
2.2
13.71
14.72
nmol/l
0.51
77
535
18
84
2.16
2.35
1.1
1.1
—
—
—
0
0
60
404
1.51
2.35
2.1
1.9
40.51
39.51
u/l
0.13
51
338
21
106
2.00
2.26
1.2
1.1
—
—
—
0
0
7
18
3.90
2.25
1.1
1.1
—
—
—
0
0
40
249
1.63
2.20
1.8
1.6
—
—
—
0
0
37
226
1.66
2.19
1.2
1.1
—
—
—
0
0
22
115
1.93
2.16
2.3
1.3
—
—
—
0
0
13
55
2.38
2.12
1.9
2.4
—
—
—
0
0
22
116
1.91
2.11
2.3
1.2
—
—
—
0
0
6
15
4.01
2.04
2.0
1.3
—
—
—
0
0
10
38
2.64
2.00
1.7
1.2
—
—
—
0
0
10
38
2.64
2.00
1.7
1.2
—
—
—
0
0
13
57
2.29
1.98
1.5
1.2
—
—
—
0
0
16
78
2.06
1.91
1.0
1.0
—
—
—
0
0
44
292
1.52
1.89
4.0
3.4
0.76
0.80
nmol/l
0.18
32
231
1020
9795
1.20
1.88
6.8
6.4
38.61
40.83
mmol/mol
12.20
977
8985
12
52
2.32
1.88
2.1
1.9
17.31
17.20
nmol/l
0.02
12
43
12
52
2.32
1.88
1.0
1.0
—
—
—
0
0
21
114
1.86
1.88
2.4
1.3
—
—
—
0
0
1113
10779
1.23
1.87
24.0
9.2
25.49
25.50
u/l
0.01
1095
10269
21
115
1.84
1.83
2.4
1.3
—
—
—
0
0
5
12
4.18
1.82
1.0
1.2
—
—
—
0
0
5
12
4.18
1.82
1.4
1.4
—
—
—
0
0
84
640
1.33
1.72
6.0
8.5
0.71
0.69
%
0.17
84
635
94
729
1.31
1.71
9.5
7.3
23.79
24.55
mmol/l
0.90
89
700
12
55
2.19
1.67
1.6
1.2
—
—
—
0
0
36
240
1.51
1.56
2.0
2.0
140.04
131.09
g/l
0.75
28
178
20
115
1.75
1.53
1.1
1.0
1.49
1.55
g/l
0.22
20
101
16
87
1.85
1.46
1.1
1.2
—
—
—
0
0
43
599
0.71
1.43
2.1
1.8
—
—
—
0
0
1071
10393
1.18
1.43
6.2
5.4
2.27
2.64
mmol/l
41.49
1021
9446
10
46
2.18
1.40
1.3
1.2
—
—
—
0
0
114
934
1.24
1.38
1.7
1.8
1.49
1.55
%
0.42
96
791
9
42
2.15
1.33
1.3
1.1
—
—
—
0
0
19
113
1.69
1.32
2.7
3.4
—
—
—
0
0
134
1125
1.21
1.30
3.8
3.2
273.37
234.17
ng/l
0.38
123
1028
5
18
2.78
1.28
1.2
1.1
—
—
—
0
0
134
1127
1.21
1.28
1.3
1.4
—
—
—
0
0
11
55
2.01
1.27
1.2
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
44
2.05
1.27
1.3
1.1
—
—
—
0
0
427
3938
1.13
1.22
4.5
3.8
1.97
2.00
ug/l
0.06
384
3509
28
188
1.50
1.22
2.1
1.9
193.14
213.16
pmol/l
0.36
28
176
5
19
2.64
1.21
1.0
2.0
—
—
—
0
0
11
57
1.94
1.17
1.3
7.1
—
69.50
—
0
18
24
159
1.52
1.12
1.0
1.1
—
—
—
0
0
5
21
2.39
1.09
1.4
1.5
—
—
—
0
0
7
34
2.06
1.03
1.1
1.1
—
—
—
0
0
9
50
1.81
0.96
3.1
2.2
58.44
46.36
umol/l
—
9
40
11
62
1.78
0.94
1.5
1.3
0.88
0.97
g/l
0.43
11
62
7
37
1.90
0.94
7.7
6.1
65.14
72.63
%
—
7
32
17
256
0.66
0.92
1.5
1.5
—
—
—
0
0
159
1404
1.15
0.90
5.0
4.9
31.52
32.96
%
1.15
130
916
29
213
1.37
0.85
2.1
1.3
—
—
—
0
0
40
311
1.30
0.81
1.1
1.9
—
—
—
0
0
10
58
1.73
0.79
1.2
2.1
—
—
—
0
0
8
48
1.67
0.78
1.1
1.4
—
—
—
0
0
0
26
0.00
0.78
0.0
2.3
—
8.65
—
0
12
33
253
1.31
0.75
1.1
1.2
—
3.23
—
0
26
65
543
1.21
0.74
2.9
2.3
1.25
1.17
%
0.43
65
538
19
133
1.43
0.73
1.7
1.3
—
—
—
0
0
9
57
1.58
0.71
2.1
1.5
2.44
2.87
u/field
—
9
44
5
26
1.93
0.70
1.6
1.1
14.54
14.29
pmol/l
—
5
19
5
27
1.85
0.68
1.4
1.1
—
—
—
0
0
5
27
1.85
0.68
1.4
1.1
—
—
—
0
0
5
27
1.85
0.68
1.2
1.1
—
—
—
0
0
9
59
1.53
0.68
1.0
1.1
275.33
241.42
mg/l
—
9
53
25
189
1.33
0.64
1.2
1.2
—
53.40
—
0
18
5
29
1.73
0.64
1.6
1.1
—
—
—
0
0
5
29
1.73
0.64
1.6
1.1
—
—
—
0
0
219
2363
0.91
0.60
4.9
4.2
1.02
1.02
kg/l
0.00
40
345
10
64
1.57
0.58
1.1
1.1
—
—
—
0
0
10
64
1.57
0.58
1.1
1.1
—
—
—
0
0
6
35
1.72
0.57
5.7
2.9
—
—
—
0
0
6
35
1.72
0.57
5.7
2.9
—
—
—
0
0
34
419
0.81
0.57
1.5
1.6
—
—
—
0
0
34
274
1.25
0.57
1.1
1.2
—
41.34
—
0
15
1129
11142
1.10
0.56
50.7
20.1
10.14
6.77
e9/l
27.39
1105
10718
126
1137
1.12
0.56
2.1
2.5
4.51
7.73
ug/l
3.06
92
995
112
1004
1.13
0.56
1.3
1.4
—
—
—
0
0
1129
11143
1.10
0.56
50.7
20.0
375.47
243.39
e9/l
104.66
1109
10764
10
65
1.54
0.55
1.1
1.1
—
—
—
0
0
10
65
1.54
0.55
1.1
1.1
—
—
—
0
0
10
65
1.54
0.55
1.1
1.1
—
—
—
0
0
1129
11146
1.10
0.54
50.7
20.0
4.83
4.47
e12/l
28.54
1102
10718
6
38
1.58
0.54
1.0
2.1
21.95
228.15
ug/l
—
6
33
1129
11148
1.10
0.53
51.0
20.2
135.86
135.57
g/l
0.21
1119
10915
1128
11138
1.10
0.53
50.3
20.1
42.22
40.02
%
21.26
1065
10184
9
62
1.45
0.53
1.4
1.3
144.83
174.26
pmol/l
—
9
62
6
39
1.54
0.53
1.8
1.4
—
—
—
0
0
1034
10179
1.08
0.50
5.4
5.0
6.02
6.07
mmol/l
0.74
956
9140
7
45
1.56
0.49
2.9
2.6
49385.71
40797.78
ug/l
—
7
45
10
142
0.70
0.46
2.1
1.8
—
—
—
0
0
5
84
0.59
0.45
1.4
1.5
—
56.67
—
0
6
8
56
1.43
0.42
1.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
11
79
1.40
0.40
1.1
1.0
303.64
281.90
mg/l
0.55
11
72
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
28
234
1.20
0.37
1.6
1.4
—
—
—
0
0
28
234
1.20
0.37
1.6
1.4
—
—
—
0
0
206
1948
1.07
0.37
1.3
1.2
0.68
1.66
u/ml
2.77
42
515
6
42
1.43
0.35
1.2
1.1
221.90
232.59
iu/ml
—
6
42
31
264
1.18
0.35
1.7
1.6
—
—
—
0
0
6
44
1.37
0.34
1.2
1.2
—
—
—
0
0
33
378
0.87
0.30
1.5
1.5
—
—
—
0
0
11
84
1.31
0.30
1.0
1.1
—
5.40
—
0
5
33
289
1.15
0.28
1.3
1.1
—
—
—
0
0
8
63
1.27
0.27
1.0
1.2
9.07
9.53
mmol/l
—
8
56
8
63
1.27
0.27
1.0
1.7
9.76
13.81
umol/l
—
8
57
9
121
0.74
0.27
2.1
1.8
—
—
—
0
0
105
985
1.07
0.26
2.5
2.1
158.28
157.90
ug/g
0.00
88
769
33
292
1.13
0.25
1.3
1.1
—
—
—
0
0
11
87
1.27
0.24
1.0
1.1
—
—
—
0
0
15
124
1.21
0.24
1.1
1.1
—
20.62
—
0
5
6
85
0.70
0.24
1.3
1.5
—
224.55
—
0
11
354
3638
0.96
0.23
3.2
3.1
7.12
7.29
mmol/l
0.29
292
3052
212
2201
0.96
0.23
2.8
2.7
0.77
0.72
ug/l
0.14
147
1475
7
91
0.77
0.22
1.1
1.6
—
27.40
—
0
20
166
1591
1.05
0.22
1.2
1.2
7.65
13.60
u/ml
0.77
66
587
17
199
0.85
0.21
1.4
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
22.62
—
0
5
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
292
2837
1.04
0.21
1.5
1.7
1.52
1.36
mmol/l
1.69
249
2344
20
173
1.16
0.21
1.6
1.4
—
—
—
0
0
33
298
1.11
0.19
1.3
1.3
—
—
—
0
0
31
279
1.11
0.19
1.5
1.5
299.88
300.44
ug/g
0.00
17
165
34
308
1.11
0.19
2.6
2.3
226.80
70.95
ug/min
0.59
20
192
7
58
1.21
0.18
1.1
1.2
—
—
—
0
0
7
58
1.21
0.18
1.1
1.2
—
—
—
0
0
144
1498
0.96
0.18
9.0
7.1
—
—
—
0
0
325
3176
1.03
0.17
3.8
3.7
21.17
24.07
%
3.13
143
1504
17
148
1.15
0.17
2.3
1.7
270.24
271.56
mu/l
0.01
17
138
11
92
1.20
0.16
1.0
1.1
—
73.91
—
0
11
44
409
1.08
0.15
1.0
1.1
—
—
—
0
0
12
103
1.17
0.13
2.4
2.5
640.57
607.86
ml
—
7
72
12
138
0.87
0.13
1.2
1.4
—
—
—
0
0
257
2523
1.02
0.11
1.7
1.7
54040924.09
19255695.53
pmol/l
0.28
198
2041
166
1623
1.03
0.10
1.3
1.3
22.04
38.68
iu/ml
2.35
58
517
5
45
1.11
0.09
1.4
1.4
—
—
—
0
0
5
46
1.09
0.09
2.8
1.1
4.78
4.24
umol/l
—
5
23
55
527
1.05
0.09
1.2
1.2
117.30
116.60
iu/ml
0.01
20
208
21
226
0.93
0.08
1.2
1.3
97.36
736.06
e6/l
0.78
14
194
21
226
0.93
0.08
1.1
1.3
1.33
43.80
e6/l
1.02
12
186
6
75
0.80
0.07
1.5
1.3
2.10
2.03
mmol/l
—
6
70
11
100
1.10
0.05
2.5
2.2
5.33
2.08
u/field
—
6
37
41
397
1.03
0.04
1.3
1.2
—
—
—
0
0
24
247
0.97
0.01
6.8
3.4
20.72
27.67
mg/l
0.57
16
162
356
3566
1.00
0.00
3.3
3.2
1151.59
164.81
mg/l
1.58
234
2253
27
272
0.99
0.00
1.4
1.6
13627.39
12823.04
e6/l
0.04
18
199
376
3761
1.00
0.00
3.8
3.8
15.90
8.01
mg/mmol
1.20
242
2353
20
205
0.98
0.00
1.3
1.9
3.89
4.70
iu/l
—
8
67
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
0.00
2.3
2.1
—
144.47
—
0
17
6
68
0.88
0.00
1.5
1.2
0.57
1.76
u/ml
—
6
43
65
650
1.00
-0.00
2.4
2.5
3.96
22.13
au/ml
—
5
24
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
19.60
—
0
5
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
54
0.93
-0.00
1.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
63
0.95
-0.00
1.0
1.7
103.17
89.14
umol/l
—
6
63
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
12.00
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint POLYCYTVERA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| POLYCYTVERA | 2.079 [1.84, 2.35] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.027 |
During the follow-up period (1.1.1998 — 31.12.2019), 1275 out of 3089 females with POLYCYTVERA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| POLYCYTVERA | 1.913 [1.67, 2.19] | < 0.001 |
| Birth year | 0.986 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 1129 out of 2970 males with POLYCYTVERA died.
Mortality risk
Mortality risk for people of age
years, who have POLYCYTVERA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.135% | 0.366% |
| 5 | 0.975% | 2.055% |
| 10 | 2.376% | 5.434% |
| 15 | 4.47% | 10.324% |
| 20 | 8.094% | 16.756% |
Relationships between endpoints
↥Index endpoint: POLYCYTVERA – Polycythaemia vera
GWS hits: 12
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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