No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
454 |
4. Check minimum number of eventsNone |
454 |
5. Include endpointsNone |
454 |
6. Filter based on genotype QC (FinnGen only) |
454 |
Control definitions (FinnGen only)
- Control exclude
- K11_OESSTODUO
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- K20-K31
- Name in latin
- Ulcus gastrojejunale
Similar endpoints
↥List of similar endpoints to
Gastrojejunal ulcer
based on the number of shared cases.
Similar with more cases:
- Gastroduodenal ulcer
- Diseases of oesophagus, stomach and duodenum
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4051 | 1650 | 2317 |
| Only index persons | 2697 | 1197 | 1500 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.05 | 0.06 |
| Only index persons | 0.05 | 0.04 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 63.10 | 65.42 | 61.36 |
| Only index persons | 60.42 | 62.20 | 59.00 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 454 | 177 | 277 |
| Unadjusted period prevalence (%) | 0.10 | 0.06 | 0.12 |
| Median age at first event (years) | 62.31 | 59.34 | 64.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 415
- Matched controls
- 4150
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K28.9
ICD-10 Finland
Gastrojejunal ulcer, unspecified as acute or chronic, without haemorrhage or perforation
+∞
236.8
204
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
18.0
143.0
273
400
K28.0
ICD-10 Finland
Gastrojejunal ulcer, acute with haemorrhage
+∞
57.6
54
*
K92.1
ICD-10 Finland
Melaena
10.4
35.3
72
82
UJF32
NOMESCO Finland
Coloscopy
4.3
34.7
163
547
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
16.3
32.0
52
36
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
+∞
29.5
28
*
A02BC03
ATC
lansoprazole; oral
3.5
26.6
163
654
K25.0
ICD-10 Finland
Gastric ulcer, Acute with haemorrhage
+∞
26.3
25
*
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
143.9
25.9
27
*
A02BC02
ATC
pantoprazole; systemic
3.1
25.7
290
1770
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.3
25.5
170
722
K28.3
ICD-10 Finland
Gastrojejunal ulcer, acute without haemorrhage or perforation
+∞
25.3
24
*
K25.3
ICD-10 Finland
Gastric ulcer, Acute without haemorrhage or perforation
253.8
23.9
24
*
K28.4
ICD-10 Finland
Gastrojejunal ulcer, chronic or unspecified with haemorrhage
+∞
23.1
22
*
K28.1
ICD-10 Finland
Gastrojejunal ulcer, acute with perforation
+∞
22.1
21
*
A02BC01
ATC
omeprazole; systemic
3.1
21.5
154
671
K29.7
ICD-10 Finland
Gastritis, unspecified
20.8
21.1
31
16
K28.7
ICD-10 Finland
Gastrojejunal ulcer, chronic without haemorrhage or perforation
+∞
21.0
20
*
UJD02
NOMESCO Finland
Gastroscopy
8.8
20.3
44
55
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.9
20.0
91
278
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
30.7
19.9
26
9
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.2
18.4
76
212
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
4.1
18.0
74
206
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.7
17.8
161
792
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
5.5
17.8
54
109
K25.4
ICD-10 Finland
Gastric ulcer, Chronic or unspecified with haemorrhage
176.6
16.6
17
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
3.2
16.4
96
354
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
31.5
16.3
21
7
K92.0
ICD-10 Finland
Haematemesis
10.4
16.0
31
32
K22.1
ICD-10 Finland
Ulcer of oesophagus
88.4
15.7
17
*
K29.3
ICD-10 Finland
Chronic superficial gastritis
58.9
14.9
17
*
5340A
ICD-9 Finland
Gastrojejunal ulcer, Acute with haemorrhage[ULCUS IN ANASTOMOSI GASTROJEJUNALE,KOMPLISOITUMATON]
+∞
14.7
14
*
K26.0
ICD-10 Finland
Duodenal ulcer, acute with haemorrhage
+∞
14.7
14
*
A02BC05
ATC
esomeprazole; systemic
2.4
14.5
171
947
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
5.8
14.0
40
75
K26.9
ICD-10 Finland
Duodenal ulcer, unspecified as acute or chronic, without haemorrhage or perforation
+∞
13.6
13
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.9
13.0
90
365
C10AC01
ATC
colestyramine; oral
9.5
12.9
26
29
5340B
ICD-9 Finland
Gastrojejunal ulcer, Acute with haemorrhage[ULCUS IN ANASTOMOSI GASTROJEJUNALE,VUOTAVA]
+∞
12.6
12
*
D64.9
ICD-10 Finland
Anaemia, unspecified
3.3
12.5
66
224
6318
FHL
Resection (2/3) and gastrojejunostomy (including Roux-Y)
133.8
12.5
13
*
N02AX02
ATC
tramadol; systemic, rectal
2.2
12.5
195
1206
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
12.2
195
1212
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.9
12.2
81
321
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
7.9
12.1
27
36
K30
ICD-10 Finland
Functional dyspepsia
4.7
12.1
41
94
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
7.7
11.9
27
37
A03FA02
ATC
cisapride; oral, rectal
4.0
11.7
48
132
C03CA01
ATC
furosemide; systemic
2.2
11.7
169
1002
A09AA02
ATC
multienzymes (lipase, protease etc.)
9.7
11.6
23
25
JN3AD
NOMESCO Finland
Abdominal CT examination
3.9
11.6
49
139
K26.3
ICD-10 Finland
Duodenal ulcer, acute without haemorrhage or perforation
+∞
11.5
11
*
K29.8
ICD-10 Finland
Duodenitis
+∞
11.5
11
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.0
11.4
69
257
P01AB01
ATC
metronidazole; oral, rectal
2.2
11.2
157
911
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
13.2
11.2
19
15
-
ICD-10 Finland
NA
7.4
11.2
26
37
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
14.4
11.1
18
13
E66.8
ICD-10 Finland
Other obesity
5.5
10.7
31
60
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
6.9
10.7
26
40
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.6
10.5
36
84
53499
ICD-8 Finland
Gastrojejunal ulcer, Other and unspecified
+∞
10.5
10
*
UJF02
NOMESCO Finland
Peroral enteroscopy
33.4
10.4
13
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.6
10.3
79
339
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
11.7
10.1
18
16
JAH01
NOMESCO Finland
Laparoscopy
5.6
9.9
28
53
H02AB06
ATC
prednisolone; systemic
2.0
9.6
197
1312
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.3
9.6
48
157
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.4
9.5
46
146
JDA60
NOMESCO Finland
Closure of perforated ulcer of stomach
+∞
9.4
9
*
L04AX01
ATC
azathioprine; systemic
5.5
9.4
27
52
A03FA01
ATC
metoclopramide; systemic, rectal
2.3
9.2
93
461
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
5.1
9.2
28
58
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
16.0
9.1
14
9
A02BA02
ATC
ranitidine; systemic
2.3
9.0
94
471
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
19.1
9.0
13
7
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
5.1
8.8
27
56
JAH00
NOMESCO Finland
Laparotomy
5.4
8.6
25
49
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
7.6
8.5
19
26
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
91.8
8.4
9
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.0
8.4
49
178
A02BA04
ATC
nizatidine; systemic
3.2
8.2
43
146
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.3
8.2
40
129
R06.0
ICD-10 Finland
Dyspnoea
2.1
8.1
107
592
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.4
8.1
28
67
A02BX02
ATC
sucralfate; oral
4.2
8.0
29
72
107
Kela drug reimbursment
Pernicious anaemia
7.5
8.0
18
25
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
6.3
7.9
20
33
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.8
7.7
50
195
N03AX12
ATC
gabapentin; oral
2.4
7.6
66
303
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
9.1
7.6
15
17
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
7.5
62
277
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
81.4
7.4
8
*
K28.6
ICD-10 Finland
Gastrojejunal ulcer, chronic or unspecified with both haemorrhage and perforation
+∞
7.3
7
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.4
7.3
34
106
J01MA02
ATC
ciprofloxacin; systemic
1.8
7.3
164
1102
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
4.5
7.1
24
56
K50.8
ICD-10 Finland
Other Crohn disease
9.0
7.1
14
16
A02BD03
ATC
lansoprazole, amoxicillin and metronidazole; systemic
3.2
7.1
36
120
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
7.1
145
940
M54.4
ICD-10 Finland
Lumbago with sciatica
2.4
7.1
62
285
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
7.0
78
402
N06AX11
ATC
mirtazapine; oral
1.9
7.0
119
724
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
7.0
49
200
N03AX16
ATC
pregabalin; oral
2.0
7.0
94
525
53299
ICD-8 Finland
Ulcer of duodenum, Other and unspecified
14.1
6.9
11
8
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
3.8
6.8
27
74
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.2
6.8
24
59
J01DB01
ATC
cefalexin; oral
1.8
6.7
304
2506
UJK02
NOMESCO Finland
ERCP
5.3
6.7
19
37
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.3
6.7
19
37
C07AB07
ATC
bisoprolol; oral
1.7
6.7
204
1490
A06AD11
ATC
lactulose; oral
2.1
6.7
77
402
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.9
6.7
39
143
UJF92
NOMESCO Finland
Capsular endoscopy
8.0
6.7
14
18
R42
ICD-10 Finland
Dizziness and giddiness
2.0
6.5
91
514
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.7
6.5
43
171
JDA42
NOMESCO Finland
Other endoscopic haemostatic procedure in stomach or pylorus
70.8
6.4
7
*
A02BA03
ATC
famotidine; systemic
4.0
6.4
24
63
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
6.4
91
515
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
11.2
6.3
11
10
D37.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Stomach
9.5
6.3
12
13
JN4BD
NOMESCO Finland
Extensive body CT
2.4
6.3
55
252
A03CA02
ATC
clidinium and psycholeptics; oral
3.1
6.3
33
113
JKA20
NOMESCO Finland
Cholecystectomy
4.2
6.3
22
54
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
18.3
6.3
9
5
K26.4
ICD-10 Finland
Duodenal ulcer, chronic or unspecified with haemorrhage
+∞
6.3
6
*
53192
ICD-8 Finland
Ulcer of stomach, Praepyloricum (haemorrhagia, stenosi sive perforatione non indicata)
+∞
6.3
6
*
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
+∞
6.3
6
*
JDC20
NOMESCO Finland
Partial gastrectomy and Roux-en-Y reconstruction
27.1
6.2
8
*
Z98.8
ICD-10 Finland
Other specified postsurgical states
8.8
6.1
12
14
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
3.9
6.1
23
61
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
127
443
3.59
30.19
17.2
7.2
—
—
—
0
0
197
940
2.94
27.10
4.2
2.3
53.9
56.4
u/l
0.41
179
862
178
812
2.96
26.48
3.3
2.0
3.7
3.2
mg/l
1.61
157
686
94
295
3.76
25.89
3.0
2.5
4.8
9.1
ug/l
1.42
89
259
58
131
4.93
24.61
4.0
3.0
1.3
1.3
mmol/l
0.19
58
126
77
221
3.99
24.00
2.1
1.7
—
—
—
0
0
40
68
6.35
23.01
1.8
1.4
230.8
279.8
ug/g
0.74
26
38
108
402
3.21
22.55
7.3
5.7
1.1
1.0
mmol/l
0.55
94
366
275
1698
2.57
21.01
8.9
6.0
11.3
12.0
umol/l
0.36
260
1609
244
1446
2.49
20.05
8.7
4.3
33.7
35.2
g/l
3.45
232
1333
150
718
2.63
19.32
7.5
3.9
1.0
1.0
kg/l
—
7
105
78
261
3.40
19.18
3.1
2.9
55.6
61.1
ml/min/173m2
0.55
32
104
121
529
2.76
18.58
4.3
3.2
0.8
0.8
mmol/l
1.28
113
491
120
524
2.75
18.46
4.1
2.3
10.3
12.5
umol/l
3.21
109
485
173
905
2.47
18.31
7.2
3.8
0.0
0.0
estimate
0.00
35
302
110
476
2.73
17.10
4.2
2.3
2.4
2.3
g/l
1.46
103
443
102
448
2.65
15.25
4.1
2.4
18.4
21.8
%
1.81
89
388
94
399
2.71
15.02
10.1
6.5
5.1
5.1
kpa
0.22
89
380
94
399
2.71
15.02
10.1
6.5
11.6
11.9
kpa
0.24
89
381
94
401
2.70
14.87
10.1
6.5
1.0
1.3
mmol/l
0.32
70
311
206
1257
2.17
14.35
4.9
2.6
115.9
152.2
ug/l
2.21
196
1136
204
1257
2.13
13.69
4.7
3.3
—
—
—
0
0
128
659
2.31
13.39
2.2
1.8
1604.2
1164.6
nmol/l
4.49
113
481
36
90
4.26
13.35
1.3
1.3
—
—
—
0
0
74
298
2.77
12.99
3.4
2.0
0.2
0.2
g/l
1.79
69
277
204
1284
2.07
12.68
6.7
3.8
—
—
—
0
0
71
284
2.78
12.61
11.1
6.8
11.9
10.9
mmol/l
0.52
64
266
227
1500
2.03
12.20
10.0
5.8
1.2
1.2
mmol/l
3.28
213
1329
51
176
3.14
11.77
3.9
3.0
24.3
25.1
mmol/l
0.82
51
171
74
318
2.59
11.38
4.6
3.9
1.7
2.0
mmol/l
0.22
61
250
241
1656
1.97
11.29
11.1
6.2
1.2
1.2
mmol/l
3.07
209
1367
203
1341
1.93
10.44
2.5
2.0
91.1
92.6
pmol/l
0.20
123
696
235
1631
1.91
10.39
6.5
3.6
0.0
0.0
estimate
0.00
38
313
323
2509
2.00
9.99
12.2
7.2
91.9
79.9
u/l
2.23
310
2326
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
38
122
3.31
9.85
2.7
2.2
0.3
0.4
u/ml
0.36
21
58
201
1342
1.89
9.85
6.3
3.8
32.6
68.9
ng/l
0.81
154
987
83
403
2.30
9.71
1.8
1.8
—
—
—
0
0
270
1991
1.88
9.59
9.1
4.5
6.8
6.8
mmol/l
0.12
256
1861
175
1125
1.90
9.58
3.7
3.3
2.3
2.3
mmol/l
1.05
157
974
19
37
5.32
9.44
1.3
1.3
—
—
—
0
0
14
20
7.19
9.33
1.1
1.4
61.2
42.2
u/l
—
9
15
161
1015
1.91
9.30
2.8
2.0
276.0
260.3
u/l
0.04
149
950
231
1633
1.84
9.28
7.5
5.0
0.0
0.0
estimate
0.49
38
310
233
1656
1.84
9.16
6.5
3.7
0.0
0.0
estimate
0.00
36
300
102
556
2.08
8.88
2.1
1.8
—
—
—
0
0
248
1812
1.81
8.76
11.5
8.9
4.8
4.2
e9/l
2.12
225
1585
106
593
2.03
8.58
2.9
2.9
1.5
1.0
e6/l
0.78
69
354
25
68
3.83
8.29
2.0
1.5
—
—
—
0
0
167
1102
1.82
8.13
3.8
3.1
1307.3
1700.6
ng/l
0.93
150
949
120
714
1.93
8.09
1.8
1.8
432.5
8650943.1
pmol/l
0.50
104
578
136
852
1.85
7.78
3.3
2.8
351.3
9135.9
umol/l
4.61
120
726
77
398
2.13
7.64
1.6
1.7
—
—
—
0
0
96
543
1.97
7.45
2.1
1.9
32.3
29.5
s
1.71
91
527
112
680
1.86
6.99
4.0
3.0
2.5
2.5
mmol/l
0.51
105
601
147
972
1.76
6.90
3.6
3.2
0.7
0.5
e6/l
0.34
124
736
37
144
2.71
6.89
3.5
1.9
2.1
3.2
ug/l
0.21
29
127
51
232
2.35
6.87
5.3
4.1
113.9
89.8
ng/l
0.57
46
201
176
1249
1.67
6.26
3.6
2.1
73.6
77.1
nmol/l
0.92
165
1088
13
26
5.12
6.26
2.1
2.4
—
—
—
0
0
207
1534
1.64
6.20
6.0
4.0
—
—
—
0
0
67
360
2.01
5.96
4.9
2.7
11.8
8.8
umol/l
0.45
56
321
29
108
2.80
5.88
1.4
1.2
2.4
2.8
u/ml
—
5
10
95
576
1.82
5.88
1.3
1.2
0.8
1.5
u/ml
1.05
39
158
43
197
2.31
5.71
2.3
1.4
—
—
—
0
0
24
83
3.00
5.55
1.6
1.2
—
—
—
0
0
24
84
2.96
5.44
1.6
1.2
—
—
—
0
0
290
2389
1.59
5.24
5.3
3.8
16.7
13.3
mm/h
2.40
271
2160
31
128
2.53
5.16
1.7
1.3
—
—
—
0
0
70
401
1.88
5.16
3.6
4.1
234.6
251.1
u/l
0.44
64
381
29
116
2.60
5.15
2.5
3.0
—
—
—
0
0
15
40
3.84
5.13
1.3
1.7
—
—
—
0
0
119
799
1.66
5.07
1.7
1.6
22.8
19.8
nmol/l
1.13
112
667
14
36
3.98
5.02
1.3
1.8
—
—
—
0
0
64
367
1.87
4.69
5.3
4.3
18.2
19.8
ug/l
0.03
52
304
11
25
4.48
4.58
4.6
2.8
—
—
—
0
0
14
39
3.67
4.52
1.7
1.3
—
—
—
0
0
12
30
4.08
4.46
1.2
1.7
—
—
—
0
0
12
30
4.08
4.46
1.2
1.7
—
—
—
0
0
12
30
4.08
4.46
1.2
1.7
—
—
—
0
0
103
689
1.64
4.40
1.8
1.8
1.2
1.3
mg/l
0.11
80
538
69
417
1.77
4.27
1.7
1.4
—
—
—
0
0
24
102
2.43
3.81
1.3
1.6
—
192.0
—
0
5
16
55
2.98
3.77
1.3
1.4
—
—
—
0
0
53
312
1.79
3.59
2.8
1.9
1.7
1.5
%
0.60
43
270
49
282
1.83
3.57
5.3
2.4
28.0
31.4
u/l
0.57
43
230
56
882
0.58
3.54
2.1
2.9
0.7
0.8
ug/l
1.02
44
592
21
87
2.48
3.52
1.8
1.4
—
—
—
0
0
17
65
2.68
3.34
1.5
1.4
—
—
—
0
0
20
84
2.44
3.27
1.5
1.5
—
—
—
0
0
7
11
6.44
3.19
1.7
2.4
78.4
84.0
%
—
7
11
12
39
3.13
3.11
1.7
1.2
117126.3
28011.8
e6/l
—
7
20
107
782
1.48
3.02
3.4
2.3
—
—
—
0
0
16
64
2.55
2.90
1.3
1.6
—
—
—
0
0
15
59
2.60
2.81
1.3
1.5
—
—
—
0
0
19
84
2.32
2.81
1.5
1.6
—
—
—
0
0
267
2312
1.38
2.80
5.1
3.6
15.2
14.9
pmol/l
1.44
244
2034
69
469
1.56
2.73
1.3
1.3
3.6
13.9
u/ml
1.92
37
190
27
141
1.97
2.66
5.3
3.7
428.9
2245.2
u/ml
0.75
22
119
31
173
1.85
2.53
10.7
9.2
23.7
24.6
mmol/l
0.62
26
163
127
994
1.39
2.43
4.8
2.9
34.5
33.0
u/l
0.22
120
951
17
77
2.25
2.40
2.1
2.0
126.7
127.3
g/l
—
10
60
9
27
3.38
2.40
1.2
1.4
—
—
—
0
0
7
17
4.16
2.37
1.7
1.6
6.1
4.9
u/field
—
7
11
9
29
3.14
2.23
1.1
1.4
—
—
—
0
0
6
14
4.33
2.15
2.7
4.9
131.2
115.4
nmol/l
—
6
14
68
488
1.46
2.10
1.4
1.3
25.9
39.1
iu/ml
0.85
20
162
232
2020
1.30
2.09
4.5
2.9
70.7
49.2
u/l
1.96
214
1874
24
410
0.56
2.05
4.6
4.6
35.6
31.3
%
1.30
19
261
13
57
2.32
1.99
5.7
5.9
—
161.4
—
0
7
12
51
2.39
1.96
1.3
1.4
—
—
—
0
0
351
3254
1.35
1.91
31.2
15.0
27.6
26.3
mg/l
0.28
314
2575
18
93
1.97
1.87
1.9
1.6
—
—
—
0
0
9
34
2.68
1.87
1.0
1.2
0.5
0.5
nmol/l
—
9
29
6
19
3.19
1.66
1.0
1.3
—
—
—
0
0
11
49
2.28
1.65
1.5
1.5
—
—
—
0
0
65
852
0.72
1.64
2.1
1.7
1.3
1.3
mmol/l
0.12
60
703
33
217
1.56
1.56
5.6
3.8
2.5
2.2
mmol/l
0.13
25
160
5
15
3.36
1.52
1.4
2.4
—
—
—
0
0
17
94
1.84
1.49
2.5
1.8
—
—
—
0
0
10
45
2.25
1.47
1.2
1.4
—
—
—
0
0
5
16
3.15
1.44
1.6
1.4
—
—
—
0
0
6
22
2.75
1.44
1.0
1.0
—
—
—
0
0
13
67
1.97
1.39
1.2
1.2
10.5
9.9
u/l
0.06
13
51
11
53
2.10
1.39
1.3
1.4
—
—
—
0
0
12
60
2.03
1.39
3.3
2.8
3.9
4.6
e9/l
0.46
12
60
24
154
1.59
1.28
1.4
1.2
196.3
146.9
iu/ml
0.17
13
66
10
48
2.11
1.28
1.6
4.3
—
5230.4
u/ml
—
0
5
11
55
2.02
1.28
1.0
1.3
—
—
—
0
0
127
1080
1.24
1.27
3.9
3.9
14.6
8.8
mg/mmol
0.66
90
669
12
63
1.93
1.24
1.3
1.4
—
—
—
0
0
11
56
1.99
1.23
1.4
1.2
—
—
—
0
0
8
38
2.12
1.19
1.0
1.1
—
—
—
0
0
12
65
1.87
1.14
3.5
3.2
57.7
57.8
%
0.01
12
65
15
88
1.73
1.12
1.7
1.3
—
—
—
0
0
33
235
1.44
1.12
5.7
3.7
5.3
5.2
kpa
0.30
33
212
7
33
2.14
1.06
1.1
1.2
—
—
—
0
0
23
154
1.52
1.06
16.8
4.3
1.4
1.6
%
0.32
18
145
12
67
1.81
1.05
1.1
1.3
—
—
—
0
0
12
67
1.81
1.05
1.1
1.3
—
—
—
0
0
5
22
2.29
1.03
1.0
1.0
—
—
—
0
0
5
22
2.29
1.03
3.8
3.6
14.8
89.2
u/ml
—
5
22
308
2898
1.20
1.00
5.8
4.3
2.0
2.4
mu/l
0.48
284
2573
5
23
2.19
0.98
4.0
1.3
—
—
—
0
0
12
69
1.76
0.97
1.7
1.5
—
—
—
0
0
16
103
1.57
0.88
2.6
2.7
25.9
25.3
mmol/l
0.19
16
87
13
80
1.64
0.85
2.8
2.3
16.6
15.9
%
—
6
38
6
32
1.89
0.82
2.3
1.6
—
—
—
0
0
323
3076
1.17
0.81
7.3
6.0
41.5
40.6
mmol/mol
0.75
308
2810
6
33
1.83
0.79
2.3
1.6
—
—
—
0
0
6
34
1.77
0.76
2.3
1.6
—
—
—
0
0
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
6
34
1.77
0.76
2.2
1.6
—
—
—
0
0
6
34
1.77
0.76
2.3
1.6
—
—
—
0
0
5
25
2.01
0.73
1.0
1.0
—
—
—
0
0
15
217
0.68
0.72
1.1
1.8
—
—
—
0
0
354
3413
1.17
0.68
35.1
17.3
139.0
139.7
mmol/l
4.10
346
3306
28
214
1.33
0.68
3.0
3.0
0.0
0.3
e6/l
2.63
28
208
355
3425
1.17
0.67
34.9
17.5
4.0
4.0
mmol/l
0.13
347
3317
5
28
1.79
0.66
1.8
3.1
—
—
—
0
0
6
35
1.72
0.58
2.3
1.6
—
—
—
0
0
6
35
1.72
0.58
2.8
3.6
31.5
8.2
nmol/l
—
6
35
6
35
1.72
0.58
2.3
1.6
—
—
—
0
0
14
98
1.44
0.57
5.5
2.4
8.0
7.8
kpa
0.12
14
86
75
658
1.17
0.56
5.7
3.6
149.5
300.4
ng/l
0.74
58
538
8
55
1.46
0.56
1.0
1.3
—
—
—
0
0
319
3076
1.12
0.53
4.8
4.0
1.3
1.3
mmol/l
0.68
302
2759
6
40
1.51
0.51
1.0
1.1
—
—
—
0
0
6
41
1.47
0.50
1.5
1.1
—
—
—
0
0
35
291
1.22
0.48
2.9
3.1
275.6
216.0
ng/l
0.38
26
268
7
48
1.47
0.47
1.1
1.0
—
—
—
0
0
44
379
1.18
0.43
7.8
3.5
—
—
—
0
0
186
1758
1.10
0.43
3.1
2.6
—
—
—
0
0
38
324
1.19
0.42
1.6
1.4
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
63
563
1.14
0.39
4.0
3.1
5.3
1.7
e6/l
0.69
32
326
8
116
0.68
0.37
3.6
1.7
—
—
—
0
0
10
73
1.38
0.35
2.1
2.3
—
—
—
0
0
114
1216
0.92
0.32
3.9
4.3
22.1
21.4
%
0.17
60
619
7
54
1.30
0.30
1.4
1.0
—
—
—
0
0
300
3073
0.93
0.28
23.3
14.2
77.5
77.0
ml/min/173m2
0.12
256
2535
353
3465
1.08
0.28
17.3
10.1
26.6
26.0
u/l
0.32
346
3318
14
114
1.24
0.25
1.3
3.7
—
2.5
—
0
12
5
38
1.32
0.23
2.0
2.4
0.8
4.3
u/field
—
5
11
10
124
0.80
0.22
3.9
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
295
2893
1.06
0.20
25.3
15.7
37.9
39.4
%
1.26
143
1956
11
90
1.23
0.19
1.4
1.9
—
—
—
0
0
356
3607
0.94
0.19
46.8
21.7
129.6
135.4
g/l
8.01
349
3533
10
82
1.22
0.17
1.5
1.2
—
—
—
0
0
8
68
1.18
0.16
1.1
1.3
—
—
—
0
0
8
68
1.18
0.16
1.0
1.2
—
—
—
0
0
8
71
1.13
0.16
1.3
1.4
—
—
—
0
0
6
78
0.77
0.15
1.7
1.4
1173.2
291.2
mu/l
—
6
72
321
3170
1.04
0.13
5.2
4.5
1.4
1.4
mmol/l
0.20
299
2856
10
86
1.17
0.11
3.6
2.4
—
—
—
0
0
5
44
1.14
0.10
1.8
1.5
—
—
—
0
0
322
3195
1.03
0.07
5.3
4.5
4.3
4.5
mmol/l
4.08
305
2903
20
211
0.95
0.04
2.5
1.7
—
—
—
0
0
152
1503
1.02
0.04
3.6
5.1
2.2
3.0
ug/l
1.26
133
1322
19
200
0.95
0.04
2.7
2.1
—
—
—
0
0
320
3188
1.01
0.02
5.9
4.6
6.2
6.0
mmol/l
1.24
304
2852
13
124
1.05
0.00
1.1
1.0
—
—
—
0
0
19
185
1.03
0.00
2.7
2.0
—
—
—
0
0
13
132
0.98
0.00
1.7
2.5
—
—
—
0
0
327
3274
1.00
0.00
5.9
5.1
2.4
2.7
mmol/l
4.39
308
2962
0
6
0.00
0.00
0.0
1.0
—
91.3
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
8.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
5
50
1.00
0.00
2.2
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
27.6
—
0
6
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
7
75
0.93
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
86
0.93
0.00
1.4
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
73.1
—
0
8
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_GJULC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_GJULC | 1.998 [1.68, 2.37] | < 0.001 |
| Birth year | 0.995 [0.98, 1.01] | 0.344 |
During the follow-up period (1.1.1998 — 31.12.2019), 427 out of 1009 females with K11_GJULC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_GJULC | 2.506 [2.12, 2.97] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 659 out of 1313 males with K11_GJULC died.
Mortality risk
Mortality risk for people of age
years, who have K11_GJULC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.189% | 0.51% |
| 5 | 1.092% | 2.866% |
| 10 | 2.778% | 7.0% |
| 15 | 5.795% | 12.272% |
| 20 | 10.163% | 20.428% |
Relationships between endpoints
↥Index endpoint: K11_GJULC – Gastrojejunal ulcer
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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