brain neoplasm: A neoplasm (disease) that involves the brain.
Benign neoplasm of brain and other parts of central nervous system
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_BRAIN_CNS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2267 |
4. Check minimum number of eventsNone |
2267 |
5. Include endpoints |
2479 |
6. Filter based on genotype QC (FinnGen only) |
2479 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D10-D36
- Name in latin
- Neoplasmata benigna systematis nervosi centralis et nervorum cranialium
Similar endpoints
↥List of similar endpoints to
Benign neoplasm of brain and other parts of central nervous system
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasms
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 16990 | 9327 | 7538 |
| Only index persons | 14502 | 8017 | 6485 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.24 | 0.27 | 0.21 |
| Only index persons | 0.27 | 0.29 | 0.25 |
| Median age at first event (years) | |||
| Whole population | 52.95 | 54.19 | 51.37 |
| Only index persons | 51.94 | 53.03 | 50.59 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2479 | 1413 | 1066 |
| Unadjusted period prevalence (%) | 0.48 | 0.48 | 0.47 |
| Median age at first event (years) | 53.69 | 52.19 | 55.68 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2228
- Matched controls
- 22280
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
11.9
323.0
689
809
D33.30
ICD-10 Finland
Acoustic neuroma
10818.7
323.0
744
*
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
90.8
323.0
507
72
D33.45
ICD-10 Finland
Benign Schwannom in the nerve root of the spinal cord
+∞
258.5
243
*
9560/0-C72.4
ICD-O-3
Schwannoma, NOS, of acoustic nerve
+∞
229.2
216
*
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
33.5
211.4
280
95
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
245.2
198.1
201
9
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
+∞
191.5
181
*
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
38.4
171.0
219
63
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
1442.6
140.1
135
*
D33.07
ICD-10 Finland
Colloid coast in cerebral ventricle
+∞
130.5
124
*
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
23.2
124.5
182
85
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
8.4
112.1
260
343
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.9
105.3
383
908
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
9.4
102.9
223
261
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
33.3
100.0
132
42
DFF00
NOMESCO Finland
Pure tone audiometry
4.4
94.3
386
1023
D33.2
ICD-10 Finland
Benign neoplasm: Brain, unspecified
477.0
93.0
92
*
D33.7
ICD-10 Finland
Benign neoplasm: Other specified parts of central nervous system
+∞
92.3
88
*
D33.02
ICD-10 Finland
Another benign medial tumor of the cerebrum
+∞
92.3
88
*
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
21.2
89.4
134
67
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
29.9
87.8
119
42
D33.39
ICD-10 Finland
Benign tumor of the cranial nerves UNS
+∞
84.9
81
*
D33.3
ICD-10 Finland
Benign neoplasm: Cranial nerves
+∞
84.9
81
*
2251A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Cranial nerves
+∞
81.8
78
*
D33.37
ICD-10 Finland
Another benign tumor of the cranial nerves
+∞
81.8
78
*
D33.40
ICD-10 Finland
Benign glioma of the spinal cord (grade I)
+∞
79.7
76
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
5.5
79.6
252
503
AA1AD
NOMESCO Finland
CT of head and brain
2.7
79.5
703
3267
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
406.5
79.4
79
*
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
94.6
74.4
82
9
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.9
71.7
526
2158
D33.43
ICD-10 Finland
Spinal cord
+∞
71.2
68
*
D33.08
ICD-10 Finland
Another benign tumor of the cerebral ventricle
710.0
70.5
69
*
2152
FHL
Extraction, big brain
98.3
69.3
76
8
D33.4
ICD-10 Finland
Benign neoplasm: Spinal cord
+∞
69.1
66
*
9560/0-C72.0
ICD-O-3
Schwannoma, NOS, of spinal cord
688.7
68.4
67
*
22500
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Brain
+∞
68.1
65
*
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
8.5
66.8
152
191
D33.10
ICD-10 Finland
Benign pilosytic astrocytoma of brain stem
+∞
61.7
59
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.9
61.5
441
1765
G91.1
ICD-10 Finland
Obstructive hydrocephalus
50.2
60.6
73
15
D33.05
ICD-10 Finland
Other lateral benign tumor in temporal lobe
+∞
59.6
57
*
N03AF02
ATC
oxcarbazepine; oral
6.1
59.0
168
292
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
24.4
54.8
78
33
2250A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Brain
+∞
54.4
52
*
D33.14
ICD-10 Finland
Hemangioblastoma and cerebellum
+∞
52.3
50
*
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
27.7
51.0
70
26
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.5
50.1
449
2022
22510
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Cranial nerves (including optic)
+∞
49.1
47
*
D33.47
ICD-10 Finland
Other benign neurofibromas in the nerve root of the spinal cord
+∞
49.1
47
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
48.8
702
3969
DFF15
NOMESCO Finland
Speech audiometry
4.5
48.4
181
428
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
130.4
48.0
51
*
AAE32
NOMESCO Finland
Translabyrinthine excision acoustic neurinome
+∞
47.0
45
*
DFF59
NOMESCO Finland
Other assessment of balance
13.5
46.1
81
62
9161/1-C71.6
ICD-O-3
Hemangioblastoma of cerebellum, NOS
+∞
46.0
44
*
N03AX14
ATC
levetiracetam; systemic
6.4
45.8
125
205
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
7.9
45.4
107
142
R51.80
ICD-10 Finland
Headache
2.5
45.2
404
1805
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
13.6
45.1
79
60
G51.0
ICD-10 Finland
Bell palsy
5.8
42.9
127
231
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
7.4
42.9
105
148
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
56.8
42.5
50
9
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
6.7
41.6
109
169
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.3
41.0
161
398
H02AB02
ATC
dexamethasone; systemic
2.7
39.5
291
1160
D33.15
ICD-10 Finland
Another benign tumor of the cerebellum
+∞
38.6
37
*
9560/0-C72.5
ICD-O-3
Schwannoma, NOS, of cranial nerve, NOS
+∞
38.6
37
*
D33.0
ICD-10 Finland
Benign neoplasm: Brain, supratentorial
+∞
37.6
36
*
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
8.9
37.4
81
94
AAE34
NOMESCO Finland
Other operations on acoustical nerv
373.3
37.1
37
*
N03AF01
ATC
carbamazepine; oral, rectal
3.6
37.0
177
521
D32.01
ICD-10 Finland
Benign tumor of meninges on interhemispheric surface
26.0
36.8
51
20
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
9.6
36.6
76
82
ZXC40
NOMESCO Finland
Use of ultrasound
12.6
36.5
66
54
H02.2
ICD-10 Finland
Lagophthalmos
26.9
36.4
50
19
9560/0-C72.9
ICD-O-3
Schwannoma, NOS, of nervous system, NOS
+∞
35.5
34
*
D33.11
ICD-10 Finland
Brain stem
+∞
35.5
34
*
ZXC95
NOMESCO Finland
Use of surgical navigator
8.6
35.2
78
94
Q85.01
ICD-10 Finland
Neurofibromatosis, type 2
+∞
34.5
33
*
D33.41
ICD-10 Finland
Myxopapillary epndymoma of the spinal cord (grade I)
+∞
34.5
33
*
XA800
NOMESCO Finland
Neuropsychological investigation
3.8
33.0
145
397
R42
ICD-10 Finland
Dizziness and giddiness
2.0
32.9
514
2924
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
32.8
411
2133
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
6.8
32.8
84
127
G93.0
ICD-10 Finland
Cerebral cysts
18.2
32.3
50
28
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
8.8
32.2
70
82
D36.1
ICD-10 Finland
Benign neoplasm: Peripheral nerves and autonomic nervous system
26.4
31.9
44
17
D43.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Spinal cord
73.3
31.9
36
5
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
37.0
31.5
40
11
D33.12
ICD-10 Finland
Cerebellum
+∞
31.3
30
*
C71.60
ICD-10 Finland
Malignant tumor of cerebellum without histology
+∞
31.3
30
*
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
23.6
31.0
44
19
2252A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Cerebral meninges
111.6
30.7
33
*
9530/0-C70.9
ICD-O-3
Meningioma, NOS, of meninges, NOS
52.2
30.4
36
7
N07CA01
ATC
betahistine; oral
2.8
30.3
210
802
D33.46
ICD-10 Finland
Benign neurofibroma in the nerve root of the spinal cord
+∞
30.3
29
*
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
9.4
30.2
63
69
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
14.1
29.9
51
37
XCK00
NOMESCO Finland
Perimetry
2.8
29.3
199
748
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
4.8
28.5
97
208
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.9
28.5
120
317
H93.1
ICD-10 Finland
Tinnitus
2.8
27.5
185
690
WF099
NOMESCO Finland
Other radiotherapy
13.7
27.3
47
35
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
30.5
27.2
36
12
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
46.3
26.5
32
7
R4110
NOMESCO Finland
Physiotherapy
1.8
26.3
603
3869
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
6.8
26.3
67
101
N03AX12
ATC
gabapentin; oral
2.0
26.2
353
1874
N03AB02
ATC
phenytoin; systemic
7.7
25.6
60
80
D33.04
ICD-10 Finland
Temporal lobe
+∞
25.0
24
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
25.0
472
2838
TAB00
NOMESCO Finland
Lumbar puncture
3.2
24.8
133
427
9530/0-C70.1
ICD-O-3
Meningioma, NOS, of spinal meninges
131.5
24.6
26
*
N76
ICPC
Neoplasm nervous system unspecified
43.4
24.6
30
7
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
5.4
24.1
74
142
D33.01
ICD-10 Finland
Medial ganglion glioma of the cerebrum
+∞
24.0
23
*
D33.42
ICD-10 Finland
Hemangioblastoma of the spinal cord
+∞
24.0
23
*
N75
ICPC
Benign neoplasm nervous system
68.2
23.8
27
*
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
31.4
23.7
31
10
N03AX16
ATC
pregabalin; oral
1.8
23.6
519
3270
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
23.4
207
905
D33.03
ICD-10 Finland
Pilosytic lateral astrocytoma of the strobe brain
+∞
22.9
22
*
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
30.4
22.8
30
10
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
7.5
22.4
53
72
ZXH01
NOMESCO Finland
Procedure performed within operation theatre
24.1
22.2
31
13
Q85.09
ICD-10 Finland
Unspecified neurofibromatosis
35.4
22.1
28
8
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
18.6
21.7
33
18
DE2CM
NOMESCO Finland
Acoustic channel extensive MRI examination with 3 Tesla magnet
22.4
21.7
31
14
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
8.3
21.7
48
59
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
8.5
21.1
46
55
D33.1
ICD-10 Finland
Benign neoplasm: Brain, infratentorial
+∞
20.9
20
*
9391/3-C72.0
ICD-O-3
Ependymoma, NOS, of spinal cord
+∞
20.9
20
*
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.8
20.2
135
502
G91.0
ICD-10 Finland
Communicating hydrocephalus
10.4
20.1
39
38
E23.00
ICD-10 Finland
Panhypopituitarism
11.4
20.0
37
33
H53.4
ICD-10 Finland
Visual field defects
4.3
19.9
75
180
9394/1-C72.0
ICD-O-3
Myxopapillary ependymoma of spinal cord
+∞
19.8
19
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
8.4
19.7
43
52
9380/3-C71.9
ICD-O-3
Glioma, malignant of brain, NOS
106.0
19.6
21
*
D32.07
ICD-10 Finland
Secondary or multiple benign tumor of the meninges below the exam
106.0
19.6
21
*
D32.05
ICD-10 Finland
Cerebral meninges
24.8
19.5
27
11
N02BE01
ATC
paracetamol; systemic, rectal
1.7
19.3
1834
16422
ZX050
NOMESCO Finland
Stereotactic radiotherapy
8.1
19.2
43
54
WX110
NOMESCO Finland
Local anesthesy
1.5
19.1
1435
12118
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.1
19.0
240
1230
101
Kela drug reimbursment
Anterior pituitary hypofunction
8.5
18.9
41
49
9421/1-C71.6
ICD-O-3
Pilocytic astrocytoma of cerebellum, NOS
+∞
18.8
18
*
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
8.3
18.7
41
50
WX882
NOMESCO Finland
High dependency care
3.5
18.6
88
258
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.7
18.6
82
227
S18
ICPC
Laceration/cut
1.5
18.5
860
6520
H53.2
ICD-10 Finland
Diplopia
3.4
18.3
91
278
ZZC00
NOMESCO Finland
Graft of fascia
44.4
18.2
22
5
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
17.7
18.2
28
16
183
Kela drug reimbursment
Lamotrigin and topiramate
7.1
18.1
44
63
H02AB09
ATC
hydrocortisone; systemic
3.9
18.1
76
202
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
52.9
18.0
21
*
H47.2
ICD-10 Finland
Optic atrophy
13.1
17.9
31
24
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
10.1
17.9
35
35
D33
ICD-10 Finland
Benign neoplasm of brain and other parts of central nervous system
+∞
17.7
17
*
D33.06
ICD-10 Finland
Plexus papilloma of the ventricle of the brain
+∞
17.7
17
*
2259X
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Nervous system, part unspecified
+∞
17.7
17
*
N03AX18
ATC
lacosamide; systemic
10.4
17.7
34
33
C71.11
ICD-10 Finland
Malignant tumor of frontal lobe grade II glioma
37.0
17.6
22
6
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
17.1
488
3272
SPAT1153
SPAT
Removal of sutures
1.5
17.0
671
4876
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
13.3
16.9
29
22
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.6
16.9
127
508
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.0
16.8
224
1177
22520
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Cerebral meninges
171.2
16.5
17
*
N03AG01
ATC
valproic acid; systemic, rectal
2.4
16.5
148
650
D43.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, unspecified
47.8
16.0
19
*
R5120
NOMESCO Finland
Preparation of an aid
3.5
16.0
74
214
G40.10
ICD-10 Finland
Simple partial seizures
8.3
16.0
35
43
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
3.8
15.8
67
180
C71.00
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles without histology
60.4
15.8
18
*
NA2DG
NOMESCO Finland
Thoracal spine very extensive MRI examination with high intensity magnet
33.6
15.7
20
6
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
6.5
15.7
40
62
2151
FHL
Resection, big brain
85.7
15.6
17
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.0
15.4
197
1014
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.2
15.3
161
763
A02BC02
ATC
pantoprazole; systemic
1.4
15.3
1312
11112
WX402
NOMESCO Finland
General anaesthesia
1.7
15.2
352
2219
D32.04
ICD-10 Finland
Secondary or multiple benign tumor of the meninges above the exam
28.8
15.2
20
7
AAF00
NOMESCO Finland
Ventriculostomy
7.5
15.2
35
47
ACB19
NOMESCO Finland
Excision of lesion of peripheral nerve other or unspecified
20.2
15.1
22
11
N05BA09
ATC
clobazam; oral
8.5
15.0
32
38
N02AX02
ATC
tramadol; systemic, rectal
1.5
14.9
840
6544
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.0
14.9
85
286
L01AX03
ATC
temozolomide; systemic
8.0
14.8
33
42
YX8AD
NOMESCO Finland
Stereotactic CT examination for dose design of radiotherapy
57.1
14.8
17
*
2312
FHL
Extirpation or destruction
57.1
14.8
17
*
D43.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other parts of central nervous system
57.1
14.8
17
*
ZXC86
NOMESCO Finland
Use of endoscopic device
11.4
14.8
27
24
UDC00
NOMESCO Finland
Ear microscopy
2.1
14.4
161
785
G50.0
ICD-10 Finland
Trigeminal neuralgia
4.2
14.3
53
127
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
6.8
14.2
35
52
C71.90
ICD-10 Finland
Malignant tumor in unspecified localization in the brain without histology
13.5
14.2
24
18
Z31.5
ICD-10 Finland
Genetic counselling
2.5
14.2
114
475
XX1ZW
NOMESCO Finland
Very extensive written report from radiologist
12.8
13.9
24
19
Q85.1
ICD-10 Finland
Tuberous sclerosis
53.7
13.8
16
*
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
7.4
13.7
32
44
Q85.0
ICD-10 Finland
Neurofibromatosis (nonmalignant)
75.6
13.6
15
*
8000/0-C72.4
ICD-O-3
Neoplasm, benign of acoustic nerve
+∞
13.6
13
*
22530
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Spinal cord
+∞
13.6
13
*
C71.20
ICD-10 Finland
Malignant tumor in temporal lobe without histology
16.3
13.4
21
13
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
6.5
13.4
34
53
L28
ICPC
Limited function/disability (L)
1.7
13.3
317
2010
D32.03
ICD-10 Finland
Benign meningioma in ventricles
21.3
13.3
19
9
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
13.0
810
6392
CBH25
NOMESCO Finland
Tarsorrhaphy
28.5
13.0
17
6
G96.0
ICD-10 Finland
Cerebrospinal fluid leak
22.7
12.9
18
8
CBH30
NOMESCO Finland
Tarsorraphy
50.3
12.8
15
*
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
2.1
12.8
139
670
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
4.6
12.7
43
95
C72.01
ICD-10 Finland
Malignant tumor of the spinal cord grade II glioma
+∞
12.5
12
*
D33.17
ICD-10 Finland
Fourth ventricle
+∞
12.5
12
*
C72.09
ICD-10 Finland
Malignant tumor of the spinal cord other histology
130.7
12.4
13
*
ZXA05
NOMESCO Finland
Left side
1.5
12.4
511
3704
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.9
12.2
178
965
XKD00
NOMESCO Finland
Uroflowmetry
1.6
12.1
299
1916
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.1
12.1
131
631
G44.2
ICD-10 Finland
Tension-type headache
1.7
11.9
256
1576
2159
FHL
Other measure in this category
46.9
11.9
14
*
DE2BM
NOMESCO Finland
Acoustic channel MRI examination with 3 Tesla magnet
46.9
11.9
14
*
9421/1-C71.9
ICD-O-3
Pilocytic astrocytoma of brain, NOS
46.9
11.9
14
*
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
3.0
11.8
67
226
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.7
11.7
243
1481
AAK40
NOMESCO Finland
Closure of cerebrospinal fluid fistula
30.2
11.6
15
5
23810
ICD-8 Finland
Neoplasm of unspecified nature of eye, brain and other parts of nervous system, Brain
65.3
11.6
13
*
C72.00
ICD-10 Finland
Malignant tumor of the spinal cord without histology
65.3
11.6
13
*
N03AX11
ATC
topiramate; oral
3.2
11.5
60
193
2253A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Spinal cord
+∞
11.5
11
*
9505/1-C71.9
ICD-O-3
Ganglioglioma, NOS, of brain, NOS
+∞
11.5
11
*
9161/1-C72.0
ICD-O-3
Hemangioblastoma of spinal cord
+∞
11.5
11
*
3252
FHL
Repair with foreign material (spring, magnet)
+∞
11.5
11
*
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
4.8
11.5
37
78
R20.2
ICD-10 Finland
Paraesthesia of skin
2.1
11.4
125
607
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.8
11.3
214
1266
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
15.1
11.3
18
12
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
8.4
11.3
24
29
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
8.1
11.1
24
30
WF002
NOMESCO Finland
Radical radiotherapy
2.2
11.0
114
537
R51
ICD-10 Finland
Headache
2.2
11.0
109
503
A06AD11
ATC
lactulose; oral
1.7
11.0
263
1668
XX3DW
NOMESCO Finland
Time consuming IT work
1.8
10.9
209
1240
G91.8
ICD-10 Finland
Other hydrocephalus
43.5
10.9
13
*
D42.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Cerebral meninges
43.5
10.9
13
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
10.9
287
1869
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
7.8
10.9
24
31
Q28.3
ICD-10 Finland
Other malformations of cerebral vessels
9.6
10.7
21
22
N18
ICPC
Paralysis/weakness
3.5
10.7
49
143
C71.12
ICD-10 Finland
Malignant tumor of frontal lobe grade III glioma
28.2
10.7
14
5
N03AX09
ATC
lamotrigine; oral
2.3
10.7
94
412
C71.21
ICD-10 Finland
Malignant tumor of temporal lobe grade II glioma
60.3
10.6
12
*
AAH50
NOMESCO Finland
Cranial nerve anastomosis
60.3
10.6
12
*
9531/0-C70.0
ICD-O-3
Meningothelial meningioma of cerebral meninges
60.3
10.6
12
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
10.4
848
6932
AAF50
NOMESCO Finland
Third ventriculostomy
+∞
10.4
10
*
22599
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Unspecified site
+∞
10.4
10
*
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
4.2
10.3
38
92
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
10.2
153
840
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
13.2
10.2
17
13
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
5.2
10.1
30
58
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
2.9
10.1
60
212
QAJ10
NOMESCO Finland
Browlift
9.2
10.0
20
22
H16.0
ICD-10 Finland
Corneal ulcer
2.2
9.9
97
449
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
2.3
9.8
93
423
R13
ICD-10 Finland
Dysphagia
2.0
9.7
129
677
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
7.4
9.7
22
30
N05BA01
ATC
diazepam; systemic, rectal
1.6
9.7
256
1665
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
9.6
234
1492
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
11.4
9.6
17
15
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
10.1
9.5
18
18
N03AE01
ATC
clonazepam; systemic
2.0
9.5
117
596
C71.29
ICD-10 Finland
Malignant tumor in temporal lobe other or unspecified histology
30.1
9.4
12
*
AAF15
NOMESCO Finland
Ventriculoatrial shunt
17.6
9.4
14
8
C71.50
ICD-10 Finland
Malignant tumor of cerebral ventricle without histology
+∞
9.4
9
*
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
+∞
9.4
9
*
2396A
ICD-9 Finland
Neoplasm of unspecified nature, Brain
+∞
9.4
9
*
Q85.82
ICD-10 Finland
of Hipple-Lindau syndrome
+∞
9.4
9
*
AWW99
NOMESCO Finland
Other reoperation in surgery of the nervous system
+∞
9.4
9
*
C75.3
ICD-10 Finland
Malignant neoplasm: Pineal gland
+∞
9.4
9
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
9.4
394
2850
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
12.4
9.4
16
13
H81.3
ICD-10 Finland
Other peripheral vertigo
2.7
9.3
63
241
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
9.3
170
997
AA1AA
NOMESCO Finland
Head X-ray examination
5.0
9.2
28
56
M03BX01
ATC
baclofen; systemic
3.3
9.2
44
134
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.5
9.2
70
286
DAX08
NOMESCO Finland
Fitting of hearing aid
2.2
9.2
89
409
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
9.2
276
1857
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.2
9.2
87
398
SPAT1043
SPAT
Audiometry
1.7
9.1
196
1207
H47.1
ICD-10 Finland
Papilloedema, unspecified
7.7
9.1
20
26
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
6.3
9.1
23
37
DE2DG
NOMESCO Finland
Acoustic channel very extensive MRI examination with high intensity magnet
11.5
9.1
16
14
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
5.9
9.0
24
41
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
4.7
9.0
29
62
2132
FHL
Ventricular operators sunt
36.8
9.0
11
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
7.1
9.0
21
30
R4120
NOMESCO Finland
Occupational therapy
1.9
9.0
128
691
R5140
NOMESCO Finland
Monitoring the use of the aid
1.7
8.9
199
1239
R51.81
ICD-10 Finland
Facial pain NOS
3.0
8.9
49
166
119
Kela drug reimbursment
Trigeminal neuralgia or glossofaryngeusneuralgia
8.0
8.8
19
24
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
8.7
413
3058
D35.30
ICD-10 Finland
Craniopharyngoma
50.2
8.7
10
*
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
6.2
8.6
22
36
R4150
NOMESCO Finland
Neuropsychological rehabilitation
5.3
8.6
25
48
N28
ICPC
Limited function/disability (N)
3.5
8.6
38
110
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
10.1
8.5
16
16
D48.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Peripheral nerves and autonomic nervous system
27.6
8.5
11
*
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
8.5
201
1274
C71.99
ICD-10 Finland
Malignant tumor in unspecified localization in the brain other or unspecified histology
20.1
8.5
12
6
2130
FHL
Ventricular atrial shunt
90.4
8.4
9
*
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.9
8.4
117
627
D42.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Meninges, unspecified
+∞
8.3
8
*
C71.6
ICD-10 Finland
Malignant neoplasm: Cerebellum
+∞
8.3
8
*
1922A
ICD-9 Finland
Malignant neoplasm of other and unspecified parts of nervous system, Spinal cord
+∞
8.3
8
*
N99
ICPC
Neurological disease other
3.9
8.3
32
82
XKD06
NOMESCO Finland
Physiologic investigation of micturition
2.4
8.3
65
271
CBW99
NOMESCO Finland
Other operation on eyelid
33.5
8.1
10
*
AWC00
NOMESCO Finland
Reoperation of nervous system because of deep wound infection in the nervous system
33.5
8.1
10
*
ZZK00
NOMESCO Finland
Graft of nerve
33.5
8.1
10
*
SPAT1229
SPAT
Assessment of need for aid
1.8
8.1
142
823
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
3.6
8.0
34
95
N06AA09
ATC
amitriptyline; systemic
1.6
8.0
187
1178
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
2.5
8.0
60
245
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
10.1
8.0
15
15
N88
ICPC
Epilepsy
5.3
8.0
23
44
R1250
NOMESCO Finland
Evaluation of functional capability
2.8
8.0
49
179
H50.2
ICD-10 Finland
Vertical strabismus
5.9
8.0
21
36
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
7.8
7.9
17
22
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
7.8
234
1573
QAJ20
NOMESCO Finland
Subperiosteal facelift
45.1
7.7
9
*
C71.22
ICD-10 Finland
Malignant tumor of temporal lobe grade III glioma
45.1
7.7
9
*
N06AX21
ATC
duloxetine; oral
1.6
7.7
193
1240
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
7.7
438
3344
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
5.6
7.7
21
38
2377A
ICD-9 Finland
Neoplasm of uncertain behaviour of endocrine glands and nervous system, Neurofibromatosis
18.4
7.6
11
6
C71.19
ICD-10 Finland
Malignant tumor of frontal lobe other or unspecified histology
18.4
7.6
11
6
N01
ICPC
Headache
1.6
7.6
176
1108
H02
ICPC
Hearing complaint
1.6
7.6
219
1459
C71.69
ICD-10 Finland
Malignant tumor of the cerebellum other or unspecified histology
80.3
7.4
8
*
3314A
ICD-9 Finland
Other cerebral degenerations, Obstructive hydrocephalus
80.3
7.4
8
*
N06AX16
ATC
venlafaxine; oral
1.5
7.4
243
1669
R11
ICD-10 Finland
Nausea and vomiting
1.7
7.4
141
841
J01DB01
ATC
cefalexin; oral
1.3
7.3
1661
15375
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.8
7.3
118
668
9413/0-C71.9
ICD-O-3
Dysembryoplastic neuroepithelial tumor of brain, NOS
+∞
7.3
7
*
3259
FHL
Other measure in this category
+∞
7.3
7
*
9361/1-C75.3
ICD-O-3
Pineocytoma of pineal gland
+∞
7.3
7
*
2311
FHL
Resection
+∞
7.3
7
*
Q85.9
ICD-10 Finland
Phakomatosis, unspecified
+∞
7.3
7
*
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.1
7.3
74
351
102
Kela drug reimbursment
Diabetes insipidus
9.4
7.3
14
15
Z97.4
ICD-10 Finland
Presence of external hearing-aid
2.0
7.3
85
426
A28
ICPC
Limited function/disability NOS
1.5
7.3
268
1884
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.2
7.2
73
343
C71.30
ICD-10 Finland
Malignant tumor in parietal lobe without histology
15.8
7.2
11
7
T88.9
ICD-10 Finland
Complication of surgical and medical care, unspecified
5.8
7.2
19
33
D32
ICD-10 Finland
Benign neoplasm of meninges
30.1
7.1
9
*
M03BX02
ATC
tizanidine; oral
1.3
7.1
1182
10483
C71.1
ICD-10 Finland
Malignant neoplasm: Frontal lobe
20.1
7.1
10
5
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
6.6
7.1
17
26
ZXA00
NOMESCO Finland
Right side
1.3
7.1
498
3932
K07.60
ICD-10 Finland
Snapping jaw
2.0
7.0
86
441
WF003
NOMESCO Finland
Adjuvant radiotherapy
2.2
7.0
68
317
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
7.0
699
5804
CBF99
NOMESCO Finland
Other operation for ectropion
10.0
7.0
13
13
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
10.0
7.0
13
13
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
6.9
762
6411
D18.0
ICD-10 Finland
Haemangioma, any site
2.6
6.9
48
188
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
6.9
421
3248
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.4
6.9
343
2559
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
3.8
6.9
27
72
G40
ICD-10 Finland
Epilepsy
3.8
6.9
27
72
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.2
6.8
66
307
A03FA01
ATC
metoclopramide; systemic, rectal
1.4
6.8
363
2737
H02.1
ICD-10 Finland
Ectropion of eyelid
4.2
6.8
24
58
G82.2
ICD-10 Finland
Paraplegia, unspecified
6.1
6.8
17
28
C71.01
ICD-10 Finland
Malignant tumor of cerebellum except lobes and ventricles grade II glioma
40.2
6.8
8
*
CBK10
NOMESCO Finland
Operation for lagophtalmus
40.2
6.8
8
*
74340
ICD-8 Finland
Other congenital anomalies of nervous system, Neurofibromatosis
40.2
6.8
8
*
AAA00
NOMESCO Finland
Exploratory craniotomy
40.2
6.8
8
*
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
6.7
189
1250
G97.8
ICD-10 Finland
Other postprocedural disorders of nervous system
22.6
6.7
9
*
C71.40
ICD-10 Finland
Malignant tumor of the occipital lobe without histology
22.6
6.7
9
*
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.7
6.6
124
733
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
2.4
6.6
53
224
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.5
6.6
204
1381
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
6.6
538
4335
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
2.9
6.6
38
133
R90.0
ICD-10 Finland
Intracranial space-occupying lesion
12.3
6.6
11
9
N40
ICD-10 Finland
Hyperplasia of prostate
1.4
6.6
336
2514
H02AB06
ATC
prednisolone; systemic
1.3
6.5
860
7389
R53
ICD-10 Finland
Malaise and fatigue
1.4
6.5
349
2635
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
1.8
6.4
110
634
2139
FHL
Other measure in this category
70.0
6.4
7
*
G03.8
ICD-10 Finland
Meningitis due to other specified causes
70.0
6.4
7
*
C71.09
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles other or unspecified histology
70.0
6.4
7
*
D16.6
ICD-10 Finland
Benign neoplasm: Vertebral column
70.0
6.4
7
*
Z98.2
ICD-10 Finland
Presence of cerebrospinal fluid drainage device
70.0
6.4
7
*
-
ICD-10 Finland
NA
2.4
6.4
50
211
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.6
6.4
170
1108
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.1
6.4
66
318
G81.1
ICD-10 Finland
Spastic hemiplegia
14.3
6.4
10
7
UKC02
NOMESCO Finland
Cystoscopy
1.4
6.4
277
2012
RS221
NOMESCO Finland
NA
3.0
6.3
34
116
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.7
6.3
118
702
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
6.0
6.3
16
27
G50.8
ICD-10 Finland
Other disorders of trigeminal nerve
11.0
6.3
11
10
G82.1
ICD-10 Finland
Spastic paraplegia
18.1
6.3
9
5
9505/1-C71.2
ICD-O-3
Ganglioglioma, NOS, of temporal lobe
+∞
6.3
6
*
3253
FHL
Tarsoraphy
+∞
6.3
6
*
G97.2
ICD-10 Finland
Intracranial hypotension following ventricular shunting
+∞
6.3
6
*
C71.51
ICD-10 Finland
Malignant tumor of cerebral ventricle ependymoma
+∞
6.3
6
*
9421/1-C72.0
ICD-O-3
Pilocytic astrocytoma of spinal cord
+∞
6.3
6
*
9560/0-C71.9
ICD-O-3
Schwannoma, NOS, of brain, NOS
+∞
6.3
6
*
D43.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Cranial nerves
26.7
6.2
8
*
9537/0-C70.0
ICD-O-3
Transitional meningioma of cerebral meninges
26.7
6.2
8
*
H01AC01
ATC
somatropin; parenteral
7.0
6.2
14
20
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
3.4
6.2
27
79
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
2.6
6.2
41
158
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
2.5
6.2
44
176
G41.9
ICD-10 Finland
Status epilepticus, unspecified
6.3
6.2
15
24
NA1DG
NOMESCO Finland
Cervical spine very extensive MRI examination with high intensity magnet
7.7
6.1
13
17
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
6.1
279
2043
Z00.0
ICD-10 Finland
General medical examination
1.4
6.0
335
2543
M79.6
ICD-10 Finland
Pain in limb
1.3
6.0
636
5298
G40.1
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
6.7
6.0
14
21
H16.8
ICD-10 Finland
Other keratitis
10.0
6.0
11
11
R1260
NOMESCO Finland
Evaluation of communicative skills
2.6
6.0
40
155
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.8
6.0
88
485
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
188
129
15.69
212.75
1.6
1.9
—
—
—
0
0
521
2351
2.54
70.16
7.0
7.8
1.2
1.1
mmol/l
0.17
393
1850
518
2359
2.51
68.23
7.1
7.8
5.1
5.1
kpa
0.11
498
2253
518
2360
2.51
68.16
7.1
7.8
16.2
12.3
kpa
26.00
496
2255
309
1098
3.07
65.55
7.2
10.0
24.3
24.4
mmol/l
0.24
298
1033
112
193
6.03
62.47
2.4
1.5
—
—
—
0
0
1338
9240
1.97
58.64
6.9
6.2
1.2
1.2
mmol/l
1.06
1258
8354
78
97
8.27
58.63
2.0
1.8
—
—
—
0
0
1422
10156
1.94
54.98
7.5
6.9
1.2
1.2
mmol/l
0.35
1280
8558
1587
12014
1.89
48.49
5.7
4.8
6.5
6.7
mmol/l
3.47
1523
11226
160
459
3.66
47.55
2.0
1.6
1186.2
1426.7
e6/l
0.10
127
368
160
459
3.66
47.55
1.9
1.5
44.9
31.5
e6/l
0.22
123
351
171
520
3.46
46.50
1.8
1.4
644.4
531.7
mg/l
1.32
164
489
299
1290
2.50
42.91
7.2
8.1
24.3
24.9
mmol/l
2.40
299
1284
777
5038
1.79
36.49
2.2
2.3
—
—
—
0
0
56
93
6.14
32.39
2.6
2.2
51.6
50.6
umol/l
0.08
50
69
139
464
3.11
32.38
1.7
1.4
3.6
3.8
mmol/l
1.96
128
436
1268
9661
1.64
31.28
3.9
4.1
—
—
—
0
0
884
6158
1.68
30.95
2.4
2.2
205.8
224.3
u/l
0.22
851
5782
276
1321
2.23
30.85
8.9
9.6
94.9
94.0
%
1.50
276
1314
359
1946
1.99
28.78
8.7
8.7
124.5
121.2
g/l
2.54
353
1871
66
151
4.46
26.71
2.1
1.2
2.7
2.0
mmol/l
1.57
61
142
42
75
5.68
22.58
2.7
2.9
28.9
29.9
umol/l
0.22
34
52
2285
21049
2.09
21.88
20.3
16.4
139.7
139.7
mmol/l
0.43
2259
20504
2286
21103
2.07
21.10
20.2
16.5
3.9
4.0
mmol/l
4.14
2257
20521
324
1919
1.79
19.32
3.1
2.2
336.5
368.4
nmol/l
2.27
301
1756
407
2576
1.69
19.17
7.7
7.3
104.7
104.3
mmol/l
0.79
398
2521
468
3149
1.60
17.15
2.0
2.2
29.1
29.8
s
1.77
460
3053
2217
20486
1.78
17.13
17.1
14.2
23.5
24.0
mg/l
0.26
1848
16171
1282
10637
1.43
16.37
6.3
6.2
10.9
11.7
umol/l
1.57
1225
10073
27
43
6.34
16.29
1.2
1.3
—
—
—
0
0
1086
8785
1.42
15.79
4.7
4.9
35.7
35.5
g/l
0.66
1011
8167
75
270
2.83
15.37
2.1
1.2
0.1
0.4
nmol/l
—
8
17
1402
11937
1.40
14.76
9.0
9.0
4.2
4.1
e9/l
0.52
1203
10403
235
1369
1.79
14.69
2.6
2.4
24.6
23.0
au/ml
0.08
15
67
379
2513
1.60
14.58
7.1
6.9
—
—
—
0
0
131
627
2.15
14.53
5.2
4.2
3.8
3.9
mmol/l
2.24
122
589
291
1824
1.67
13.99
8.0
7.4
1.3
1.3
mmol/l
0.62
281
1760
218
1267
1.79
13.73
9.2
7.4
25.3
24.6
mmol/l
2.58
209
1179
73
277
2.68
13.57
5.2
7.0
9.9
11.8
mg/l
2.96
64
258
213
1239
1.79
13.37
1.4
1.3
38.8
46.8
au/ml
0.27
12
59
1768
15787
1.42
13.35
8.0
7.5
76.6
78.7
u/l
1.25
1686
14847
1758
15735
1.40
12.69
4.6
4.0
14.8
14.8
pmol/l
0.37
1609
14296
1527
13438
1.36
11.68
5.5
4.5
606.1
1763.6
e6/l
1.17
22
186
130
674
1.98
11.67
2.3
1.6
427.2
308.1
mu/l
1.36
125
610
463
3359
1.47
11.53
3.2
3.4
0.8
0.8
mmol/l
0.75
434
3145
1690
15125
1.37
11.50
4.4
4.1
11.1
12.2
mm/h
2.67
1571
13977
108
542
2.04
10.64
2.0
1.4
7.6
9.6
u/l
0.92
82
436
1017
8506
1.33
10.57
2.4
2.3
77.3
76.9
nmol/l
0.18
918
7629
277
1855
1.56
10.06
5.3
7.6
8.5
9.6
mmol/l
1.46
263
1767
2018
18786
1.40
9.39
5.3
4.8
1.9
2.1
mu/l
1.36
1852
17183
28
75
3.76
9.33
1.2
1.1
75.6
540.6
ng/l
—
8
20
2052
19177
1.41
9.16
15.3
13.1
83.2
81.1
ml/min/173m2
4.05
1754
15788
179
1108
1.66
9.00
10.8
10.9
—
—
—
0
0
462
3494
1.40
8.95
2.9
2.7
1.0
1.3
e6/l
0.79
269
1974
49
190
2.61
8.84
1.1
1.0
—
—
—
0
0
56
232
2.45
8.82
1.3
1.4
265.4
292.4
pmol/l
0.23
45
175
915
7704
1.30
8.53
3.6
3.6
35.3
51.7
ng/l
0.86
634
5256
39
138
2.86
8.38
1.1
1.1
—
—
—
0
0
489
3772
1.37
8.35
3.0
3.0
2.4
2.5
mmol/l
1.21
420
3313
693
5637
1.32
8.28
3.6
3.1
0.4
0.4
e6/l
0.03
545
4232
1127
9787
1.28
8.11
6.2
5.9
57.2
57.0
%
0.19
1058
9153
1141
9926
1.28
8.09
6.5
6.1
27.8
28.1
%
0.49
1065
9255
833
6965
1.30
8.08
3.4
3.3
2.4
2.4
mmol/l
0.18
710
6094
544
4287
1.34
8.06
2.8
2.6
4.4
5.9
e6/l
2.76
482
3755
371
2765
1.40
7.77
5.2
5.9
1.0
1.0
mmol/l
0.89
342
2561
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
35
123
2.87
7.64
1.2
1.1
—
—
—
0
0
38
141
2.72
7.51
1.1
1.1
302.2
272.3
mg/l
0.32
32
120
33
118
2.82
7.01
1.1
1.1
1.0
1.2
u/l
1.69
16
64
32
114
2.83
6.84
1.2
1.1
—
—
—
0
0
10
14
7.17
6.70
1.0
1.2
—
—
—
0
0
579
4715
1.30
6.65
1.6
1.5
20.6
20.7
nmol/l
0.02
494
4001
955
8304
1.24
6.28
2.1
2.0
95.3
95.4
pmol/l
0.01
512
4294
426
3352
1.33
6.25
1.8
1.8
—
—
—
0
0
2263
21792
1.44
6.12
11.7
10.4
26.1
26.2
u/l
0.12
2207
21019
748
6368
1.25
5.85
2.8
2.6
57.5
57.0
u/l
0.07
688
5875
412
3259
1.32
5.80
3.1
2.9
2.4
2.5
e6/l
0.12
224
1750
178
1235
1.48
5.50
1.7
1.6
—
—
—
0
0
131
853
1.57
5.45
1.9
1.9
38.1
39.0
u/l
0.21
115
754
1129
10137
1.21
5.09
4.4
3.6
0.0
0.0
estimate
0.80
190
1850
19
60
3.18
5.04
1.1
1.1
—
—
—
0
0
10
19
5.28
5.04
1.4
1.1
—
—
—
0
0
19
61
3.13
4.91
1.1
1.1
—
—
—
0
0
2340
22780
1.49
4.90
25.5
20.8
252.2
251.0
e9/l
0.40
2300
22190
32
137
2.35
4.83
1.0
1.2
—
—
—
0
0
128
855
1.52
4.79
1.8
1.4
29.4
29.1
iu/l
0.04
110
715
526
4390
1.25
4.78
4.8
4.0
1.0
1.0
kg/l
0.04
75
615
1111
10005
1.20
4.74
4.3
3.6
0.0
0.0
estimate
0.00
186
1880
2340
22795
1.47
4.72
25.5
20.8
4.5
4.5
e12/l
0.07
2300
22141
1459
13480
1.20
4.67
3.7
3.1
49.2
48.7
u/l
0.09
1384
12552
2340
22801
1.47
4.65
25.7
21.0
134.6
135.3
g/l
1.59
2327
22467
22
80
2.77
4.61
1.2
1.2
—
—
—
0
0
2339
22798
1.46
4.54
25.6
20.9
6.8
6.7
e9/l
0.35
2300
22146
1112
10043
1.19
4.52
5.7
4.9
0.0
0.0
estimate
0.50
191
1920
763
6659
1.21
4.49
3.6
3.2
34.0
33.9
u/l
0.02
725
6331
220
1649
1.37
4.45
2.6
2.6
72.3
66.4
ml/min/173m2
0.35
78
660
19
65
2.94
4.44
1.1
1.1
—
—
—
0
0
30
131
2.31
4.36
1.2
1.1
0.1
3.5
nmol/l
—
6
25
19
66
2.89
4.33
1.1
1.1
—
—
—
0
0
1399
12943
1.19
4.19
2.9
3.0
—
—
—
0
0
20
73
2.75
4.18
1.4
1.1
—
—
—
0
0
11
27
4.09
4.16
1.0
1.0
—
—
—
0
0
450
3764
1.24
3.96
1.8
1.7
1170.4
1186.6
nmol/l
0.11
344
2850
312
2502
1.28
3.94
4.9
4.5
32.2
32.4
%
0.12
219
1689
12
33
3.65
3.92
1.7
1.3
—
—
—
0
0
603
5214
1.21
3.82
2.3
2.2
3.0
3.0
mg/l
0.05
504
4427
194
1462
1.35
3.82
2.7
2.2
12.1
12.8
nmol/l
0.52
170
1290
46
250
1.86
3.80
1.1
1.1
—
—
—
0
0
6
5
12.02
3.76
1.0
1.0
—
—
—
0
0
113
777
1.48
3.74
1.6
1.8
—
—
—
0
0
438
3678
1.23
3.71
3.1
3.0
0.8
0.8
ug/l
0.20
299
2424
54
313
1.74
3.63
5.7
5.2
372.8
365.9
umol/l
0.14
48
271
584
5058
1.20
3.62
4.6
4.3
21.7
21.5
%
0.16
311
2448
7
9
7.80
3.56
1.1
1.4
—
—
—
0
0
181
1366
1.35
3.55
3.4
3.9
5.1
5.2
kpa
0.45
161
1268
24
105
2.30
3.52
3.0
1.2
72.0
68.4
%
—
5
13
283
2278
1.27
3.48
4.1
4.4
240.2
251.4
u/l
0.56
265
2152
50
288
1.75
3.45
1.7
1.5
0.3
0.3
nmol/l
0.69
40
222
972
8831
1.17
3.37
2.8
2.8
118.3
126.7
ug/l
0.46
889
8156
10
27
3.71
3.35
1.2
1.3
—
—
—
0
0
119
852
1.42
3.23
1.6
1.9
—
—
—
0
0
16
60
2.68
3.22
1.1
1.1
—
—
—
0
0
165
1250
1.34
3.18
3.1
3.3
4.4
4.5
pmol/l
0.40
150
1099
286
2331
1.26
3.18
1.8
1.7
—
—
—
0
0
286
2338
1.25
3.10
1.9
1.8
—
—
—
0
0
10
29
3.46
3.04
1.2
1.2
—
—
—
0
0
169
1296
1.33
3.01
3.3
3.9
1.3
1.8
mmol/l
1.31
122
976
18
75
2.41
2.97
1.1
1.0
—
—
—
0
0
8
17
4.72
2.92
1.0
1.1
—
—
—
0
0
613
5424
1.17
2.91
5.1
4.0
0.0
0.0
estimate
1.28
188
1848
10
30
3.34
2.90
2.6
3.5
46.0
45.9
umol/l
—
10
23
113
820
1.40
2.87
6.6
5.7
1.6
1.6
%
0.01
106
762
700
6279
1.16
2.77
5.3
4.9
3.2
2.7
ug/l
0.40
627
5623
188
1486
1.29
2.71
1.6
1.6
—
—
—
0
0
84
587
1.45
2.65
1.7
1.7
—
—
—
0
0
6
11
5.46
2.54
1.2
1.1
—
—
—
0
0
399
3445
1.19
2.52
1.3
1.3
37.5
34.1
iu/ml
0.17
116
1076
2034
19713
1.18
2.51
4.9
4.5
5.8
5.9
mmol/l
5.32
1856
17944
84
595
1.43
2.49
2.0
2.2
9277.3
4348.7
u/l
0.56
19
241
8
21
3.82
2.46
1.5
1.1
2.6
5.6
nmol/l
—
8
21
116
870
1.35
2.45
3.4
4.2
24.9
24.8
mmol/l
0.21
105
816
75
524
1.44
2.40
1.9
2.1
10.8
11.7
mg/l
0.51
69
484
86
617
1.41
2.39
1.5
1.5
—
—
—
0
0
8
22
3.64
2.36
1.0
1.1
—
—
—
0
0
25
133
1.89
2.31
1.1
1.0
563.1
676.9
ng/l
1.01
15
82
25
133
1.89
2.31
1.1
1.0
312.7
309.5
ng/l
0.02
13
85
8
23
3.49
2.27
1.1
1.2
—
—
—
0
0
25
135
1.86
2.22
1.1
1.0
44.1
47.0
ng/l
0.13
13
82
13
54
2.41
2.19
1.2
1.1
—
—
—
0
0
233
1941
1.22
2.17
3.8
4.0
5.8
5.9
kpa
0.06
228
1881
301
2570
1.19
2.17
21.4
25.0
1.4
1.3
inr
0.47
35
362
7
19
3.69
2.15
1.0
1.1
—
—
—
0
0
7
19
3.69
2.15
1.0
1.1
—
—
—
0
0
7
19
3.69
2.15
1.1
1.2
—
—
—
0
0
47
307
1.54
2.11
1.3
1.2
3.0
5.6
u/ml
1.07
25
132
835
7701
1.13
2.10
4.7
3.8
—
—
—
0
0
8
25
3.21
2.09
1.1
1.0
—
—
—
0
0
443
3920
1.16
2.08
3.9
3.7
144.5
413.4
ng/l
3.86
345
3032
192
1579
1.23
2.04
4.1
3.9
85.3
87.9
ng/l
0.16
170
1371
62
433
1.44
2.03
1.1
1.4
—
—
—
0
0
24
132
1.83
2.03
1.1
1.2
—
—
—
0
0
83
613
1.37
1.99
1.2
1.1
—
—
—
0
0
230
1933
1.21
1.98
3.9
4.0
2.1
1.9
mmol/l
0.24
199
1555
121
946
1.29
1.97
3.5
3.0
0.7
0.6
%
0.73
115
912
89
668
1.34
1.93
2.8
2.6
1.4
1.0
g/l
0.31
72
588
8
27
2.97
1.93
1.1
1.0
—
—
—
0
0
185
1531
1.23
1.87
3.2
2.8
10.2
10.5
g/l
0.34
169
1392
268
2298
1.19
1.87
2.3
2.7
1.8
1.8
%
0.29
232
2039
81
603
1.35
1.87
1.2
1.1
—
—
—
0
0
47
317
1.49
1.86
1.3
1.2
3.8
4.0
u/ml
0.03
19
108
209
1754
1.21
1.84
2.6
2.4
5.6
7.0
ug/l
0.99
183
1557
315
2742
1.17
1.84
2.6
2.6
22.3
22.8
%
0.25
273
2361
8
29
2.76
1.79
1.0
1.5
4.8
359095.6
nmol/l
—
8
22
80
600
1.34
1.77
2.7
2.7
171.8
184.8
%
0.79
74
573
1926
18721
1.13
1.76
5.9
5.7
38.8
39.8
mmol/mol
5.49
1778
17324
78
584
1.35
1.75
1.4
1.3
—
—
—
0
0
1766
17087
1.12
1.73
20.3
17.2
13.7
13.7
%
0.12
1739
16693
74
552
1.35
1.71
1.3
1.2
17.9
35.4
u/ml
—
7
28
25
150
1.67
1.63
1.3
1.4
1.5
1.1
promille
0.47
18
117
5
14
3.58
1.61
1.6
1.4
10.4
16.8
%
—
5
9
147
1209
1.23
1.61
1.5
1.5
—
—
—
0
0
629
5788
1.12
1.60
2.9
3.0
1047.5
1356.9
ng/l
1.43
532
4947
8
32
2.50
1.59
1.0
1.1
—
—
—
0
0
357
3180
1.14
1.55
2.4
2.5
13.0
13.1
umol/l
0.04
325
2943
29
184
1.58
1.54
1.2
1.2
—
—
—
0
0
5
15
3.34
1.52
2.0
1.3
35.6
43.3
%
—
5
9
55
401
1.38
1.49
1.6
1.7
—
—
—
0
0
280
2459
1.16
1.49
2.1
2.3
140.8
136.0
ug/g
0.07
216
1938
72
549
1.32
1.47
1.3
1.3
—
—
—
0
0
65
489
1.34
1.46
1.3
1.7
—
—
—
0
0
9
38
2.37
1.45
1.6
2.2
23.9
17.5
umol/l
—
9
38
60
448
1.35
1.42
2.5
3.1
32.9
35.6
umol/l
0.41
52
385
331
2953
1.14
1.41
2.4
2.5
2.3
2.3
g/l
0.00
300
2737
75
582
1.30
1.37
1.7
1.6
0.2
0.2
g/l
0.98
70
550
6
23
2.61
1.36
1.5
2.1
—
—
—
0
0
15
82
1.83
1.35
1.0
1.1
1159.8
1625.4
miu/ml
0.73
15
82
31
207
1.50
1.35
3.2
2.5
—
—
—
0
0
79
619
1.29
1.35
2.1
2.4
39.0
37.8
g/l
0.93
64
535
221
1924
1.16
1.34
2.6
2.4
31.0
63.9
u/l
0.73
184
1651
10
47
2.13
1.33
1.0
1.1
0.7
0.7
umol/24h
—
5
29
36
249
1.45
1.33
1.1
1.4
—
—
—
0
0
93
748
1.25
1.30
1.2
1.2
0.3
0.8
u/ml
1.10
12
67
57
748
0.76
1.29
1.4
1.5
—
—
—
0
0
8
34
2.36
1.29
1.0
1.1
—
—
—
0
0
5
18
2.78
1.28
2.0
5.3
—
—
—
0
0
37
260
1.43
1.27
1.3
1.3
—
—
—
0
0
36
252
1.43
1.26
1.1
1.4
—
—
—
0
0
234
2058
1.15
1.25
3.7
4.2
9.1
19.9
ug/l
1.07
190
1680
123
1025
1.21
1.24
3.9
4.6
24.5
24.1
mmol/l
0.82
113
930
36
253
1.43
1.24
1.1
1.4
—
—
—
0
0
78
619
1.27
1.23
1.6
1.6
0.1
10.9
iu/ml
0.50
17
111
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
84
673
1.26
1.22
2.7
3.3
0.4
0.4
u/ml
0.04
46
387
68
531
1.29
1.22
3.2
3.2
24.2
25.1
mmol/l
1.07
56
463
33
229
1.45
1.22
1.6
1.7
—
—
—
0
0
24
156
1.54
1.20
1.1
1.3
11.8
12.1
mmol/l
—
8
48
6
26
2.31
1.18
1.0
1.2
—
—
—
0
0
8
38
2.11
1.18
1.0
1.1
—
—
—
0
0
12
64
1.88
1.18
1.2
1.0
79.3
91.0
%
—
6
35
11
57
1.93
1.17
1.5
2.8
—
—
—
0
0
11
57
1.93
1.17
1.5
2.8
—
—
—
0
0
69
545
1.27
1.14
1.2
1.1
—
—
—
0
0
35
250
1.41
1.12
1.1
1.4
—
—
—
0
0
35
250
1.41
1.12
1.1
1.4
—
—
—
0
0
11
196
0.56
1.12
1.3
1.4
4.7
6.5
mmol/l
1.28
11
182
11
58
1.90
1.12
1.4
1.1
—
—
—
0
0
150
1739
0.85
1.11
1.8
1.7
—
—
—
0
0
100
828
1.22
1.10
2.2
2.0
2.2
1.7
ug/l
0.34
85
738
30
209
1.44
1.10
1.7
1.7
—
—
—
0
0
492
4560
1.10
1.09
1.3
1.3
1.8
1.4
u/ml
0.26
134
1193
110
921
1.20
1.09
2.2
1.8
—
—
—
0
0
363
3314
1.11
1.09
1.3
1.2
15.5
11.5
u/ml
0.17
145
1293
472
4368
1.10
1.08
1.7
1.7
17571501.1
34825067.2
pmol/l
0.42
387
3621
35
252
1.39
1.08
1.1
1.4
—
—
—
0
0
88
722
1.23
1.07
2.1
2.5
10.2
10.3
g/l
0.05
69
621
68
543
1.26
1.05
1.4
1.4
—
—
—
0
0
76
617
1.24
1.03
1.7
1.9
—
—
—
0
0
9
47
1.92
1.02
1.2
1.1
—
—
—
0
0
189
1667
1.14
1.01
2.9
2.7
66.3
66.5
g/l
0.15
165
1530
73
592
1.24
1.00
2.2
2.4
0.1
0.0
g/l
0.57
66
549
220
1962
1.13
1.00
2.3
2.2
0.2
0.2
g/l
0.18
205
1836
56
441
1.28
0.98
2.4
2.3
131.6
129.7
g/l
0.22
37
329
41
309
1.33
0.98
1.2
1.1
—
—
—
0
0
5
23
2.18
0.98
2.0
1.6
—
—
—
0
0
387
3567
1.10
0.98
1.6
1.5
—
—
—
0
0
63
504
1.26
0.98
1.3
1.2
62.8
3.3
u/ml
—
5
52
64
513
1.25
0.97
1.3
1.2
2.0
9.4
u/ml
—
8
84
0
30
0.00
0.97
0.0
1.2
—
1118.1
—
0
22
88
732
1.21
0.96
2.1
2.5
3.0
3.1
g/l
0.80
65
582
121
1037
1.18
0.95
2.6
2.7
0.3
0.3
e6/l
0.16
116
1009
10
55
1.82
0.92
1.0
1.4
—
—
—
0
0
30
407
0.73
0.91
1.3
1.4
—
—
—
0
0
2080
20491
1.09
0.91
5.1
4.9
2.8
2.8
mmol/l
0.24
1921
18878
30
406
0.74
0.90
1.3
1.4
—
—
—
0
0
11
63
1.75
0.90
1.3
1.4
77.8
89.7
%
—
6
35
30
405
0.74
0.89
1.3
1.4
—
—
—
0
0
570
5367
1.08
0.89
2.6
2.7
976.0
5704.1
umol/l
6.56
499
4656
45
350
1.29
0.89
1.6
1.2
31.3
43.7
u/l
0.47
35
297
12
71
1.69
0.88
1.3
1.2
—
—
—
0
0
92
776
1.19
0.88
2.1
2.5
3.6
3.8
g/l
0.68
64
567
30
404
0.74
0.88
1.3
1.4
—
—
—
0
0
70
575
1.22
0.88
4.8
4.5
1.4
1.5
mg/l
0.50
63
533
66
539
1.23
0.88
1.3
1.2
—
—
—
0
0
92
777
1.19
0.87
2.1
2.5
7.1
7.4
g/l
0.65
66
595
92
777
1.19
0.87
2.1
2.5
—
—
—
0
0
63
770
0.81
0.87
1.6
1.7
5.1
3.7
mg/l
0.29
45
534
15
95
1.58
0.87
3.1
2.4
—
—
—
0
0
1963
19302
1.08
0.87
4.1
3.9
1.3
1.3
mmol/l
0.80
1791
17668
2030
19988
1.09
0.86
4.6
4.3
1.5
1.5
mmol/l
1.23
1877
18406
68
559
1.22
0.85
2.3
2.5
0.0
0.0
g/l
0.00
61
518
75
623
1.21
0.85
3.3
3.4
2.2
1.5
ratio
—
5
51
42
326
1.29
0.85
1.4
1.2
—
—
—
0
0
10
57
1.76
0.83
1.2
1.1
—
—
—
0
0
42
327
1.29
0.83
3.4
3.6
1.2
1.4
%
0.25
35
258
121
1052
1.16
0.82
1.2
1.3
—
—
—
0
0
8
46
1.74
0.82
1.4
1.3
—
—
—
0
0
34
258
1.32
0.81
1.2
1.3
6.6
7.4
mmol/l
1.36
22
186
11
177
0.62
0.81
1.1
1.4
877.7
348.0
u/l
0.64
11
172
50
400
1.26
0.81
1.2
1.2
31.7
51.8
u/ml
—
7
39
22
155
1.42
0.81
1.8
1.7
—
—
—
0
0
67
554
1.22
0.81
2.3
2.5
0.0
0.0
g/l
0.00
61
517
11
176
0.62
0.79
1.0
1.0
—
—
—
0
0
78
657
1.19
0.78
1.7
1.7
—
—
—
0
0
2042
20133
1.08
0.78
4.6
4.4
4.7
4.7
mmol/l
0.56
1897
18661
13
82
1.59
0.78
1.1
1.2
—
—
—
0
0
131
1152
1.14
0.78
2.3
1.9
—
—
—
0
0
36
279
1.29
0.75
1.2
1.1
7.0
2.5
u/ml
0.55
16
122
480
4525
1.08
0.74
1.8
1.8
1.2
1.2
mg/l
0.00
357
3452
8
132
0.60
0.73
1.0
1.3
20.2
12.3
u/l
—
8
121
16
108
1.48
0.73
1.8
1.4
—
—
—
0
0
7
39
1.80
0.72
1.4
1.3
—
—
—
0
0
45
362
1.25
0.72
1.7
1.7
—
—
—
0
0
35
444
0.79
0.71
1.4
1.5
—
—
—
0
0
5
26
1.92
0.70
2.0
2.3
—
—
—
0
0
75
639
1.18
0.69
3.4
3.4
47.5
62.4
mg/l
0.51
63
522
9
59
1.53
0.68
1.7
2.3
—
—
—
0
0
16
110
1.46
0.68
1.9
1.8
1.1
4.0
u/field
—
9
85
75
640
1.18
0.68
3.5
3.4
35.2
79.1
mg/l
1.15
63
524
20
144
1.39
0.68
1.5
1.7
—
—
—
0
0
26
196
1.33
0.67
1.2
1.2
97.1
57.4
u/l
0.62
15
141
27
205
1.32
0.67
3.0
3.4
57.3
57.3
%
0.00
20
138
17
119
1.43
0.67
1.2
1.5
4.8
7.6
u/l
1.18
12
99
7
43
1.63
0.66
1.3
1.0
—
—
—
0
0
5
28
1.79
0.66
2.0
2.2
—
—
—
0
0
12
179
0.67
0.66
1.2
1.1
—
—
—
0
0
5
29
1.73
0.64
1.0
1.1
2.0
1.8
umol/24h
—
5
29
19
138
1.38
0.62
2.2
2.2
609.8
720.8
e6/l
—
9
58
36
288
1.25
0.62
1.7
1.6
—
—
—
0
0
16
113
1.42
0.61
1.9
1.5
13.6
7.3
ug/l
0.53
16
96
52
435
1.20
0.60
1.7
1.7
—
—
—
0
0
0
20
0.00
0.60
0.0
1.4
—
15.6
—
0
20
19
139
1.37
0.60
1.1
1.1
—
—
—
0
0
19
139
1.37
0.60
1.1
1.1
—
—
—
0
0
17
122
1.40
0.60
1.1
1.1
1.1
1.1
ratio
—
7
51
19
140
1.36
0.58
1.1
1.1
—
—
—
0
0
19
140
1.36
0.58
1.1
1.1
—
—
—
0
0
15
106
1.42
0.57
1.0
1.1
—
—
—
0
0
6
36
1.67
0.56
1.0
1.1
82.2
92.7
%
—
6
36
6
36
1.67
0.56
1.0
1.1
—
—
—
0
0
19
141
1.35
0.56
1.1
1.1
—
—
—
0
0
249
2320
1.08
0.55
2.7
2.8
7.6
8.1
umol/l
0.19
217
2023
1903
18785
1.06
0.55
18.8
15.2
39.7
39.8
%
0.13
1368
13515
40
330
1.22
0.54
1.1
1.1
—
—
—
0
0
19
142
1.34
0.54
1.4
1.4
43.1
57.5
pmol/l
—
9
45
31
249
1.25
0.53
1.7
2.4
31.0
27.0
mg/l
—
9
64
18
238
0.75
0.53
1.5
1.5
—
—
—
0
0
56
480
1.17
0.52
1.4
1.7
9088.9
14282.6
e6/l
0.76
44
350
102
913
1.12
0.52
1.6
1.9
1.6
1.5
g/l
0.45
90
791
6
40
1.50
0.51
1.3
1.5
—
—
—
0
0
81
716
1.14
0.50
3.6
3.4
114.9
5707.1
u/ml
0.84
74
616
6
41
1.46
0.50
1.0
1.1
—
6.9
—
0
6
24
189
1.27
0.49
1.7
1.4
25.1
31.0
%
0.54
18
115
14
190
0.74
0.49
1.1
1.3
1.6
1.4
nmol/l
0.27
14
167
12
84
1.43
0.49
2.0
3.4
389.8
130.8
umol/l
—
5
51
148
1359
1.09
0.48
1.2
1.2
140.5
147.2
iu/ml
0.07
57
504
29
355
0.81
0.48
1.3
1.5
—
—
—
0
0
8
120
0.67
0.45
1.3
1.3
—
—
—
0
0
37
439
0.84
0.45
3.6
4.0
17.6
25.9
mg/l
1.53
16
276
14
103
1.36
0.45
1.0
1.1
—
14.6
u/ml
—
0
9
57
498
1.15
0.44
1.9
1.9
3.2
4.8
iu/l
1.11
19
169
18
230
0.78
0.43
2.7
1.7
15.4
21.6
ug/l
1.90
18
225
5
32
1.56
0.42
2.2
1.5
—
—
—
0
0
5
32
1.56
0.42
1.0
3.1
—
—
—
0
0
24
195
1.23
0.40
4.8
3.6
—
—
—
0
0
5
35
1.43
0.39
2.2
3.0
14.5
15.1
ml/dl
—
5
30
26
312
0.83
0.38
1.4
1.7
—
—
—
0
0
48
420
1.15
0.38
2.6
2.6
16.4
16.2
%
0.06
28
218
14
107
1.31
0.37
1.2
1.7
6.2
7.9
mmol/l
—
5
65
5
37
1.35
0.37
1.0
1.5
—
—
—
0
0
9
70
1.29
0.36
2.9
2.5
28.8
27.6
%
—
9
63
22
267
0.82
0.36
1.4
1.5
—
—
—
0
0
22
180
1.22
0.36
2.8
4.7
390.5
44.6
u/ml
—
7
51
26
217
1.20
0.35
3.6
6.3
6.7
7.3
mmol/l
0.38
20
182
48
423
1.14
0.35
2.0
3.3
12.8
963.2
u/ml
0.94
39
395
6
43
1.40
0.35
1.2
1.0
22.0
20.2
mmol/l
—
6
35
20
244
0.82
0.35
1.1
1.1
2.4
5.0
u/ml
0.77
12
104
27
227
1.19
0.34
1.7
1.7
—
—
—
0
0
42
478
0.88
0.34
1.4
1.4
—
—
—
0
0
29
247
1.18
0.33
1.0
1.1
—
—
—
0
0
19
155
1.23
0.32
1.6
1.7
—
—
—
0
0
6
47
1.28
0.32
1.0
1.1
—
—
—
0
0
63
696
0.90
0.32
1.4
1.8
—
—
—
0
0
7
52
1.35
0.31
1.4
1.1
—
—
—
0
0
14
111
1.26
0.30
1.2
1.9
—
—
—
0
0
14
111
1.26
0.30
1.2
1.9
—
—
—
0
0
67
611
1.10
0.29
1.4
1.4
286.6
284.4
ug/g
0.03
42
350
255
2443
1.05
0.29
2.0
1.8
1.5
1.5
%
0.24
230
2131
44
492
0.89
0.28
2.4
2.4
51.5
126.6
ug/min
1.99
31
307
64
584
1.10
0.28
1.3
1.3
154.9
217.3
miu/ml
0.66
22
264
658
6432
1.03
0.27
3.3
3.2
7.7
7.5
mmol/l
0.48
562
5432
42
375
1.12
0.27
1.6
1.4
100.2
119.0
u/ml
—
10
66
36
405
0.89
0.26
2.9
3.2
0.7
0.8
nmol/l
1.64
21
320
61
558
1.10
0.26
1.1
1.1
4.8
5.1
u/ml
—
9
70
16
132
1.21
0.25
2.6
2.3
—
—
—
0
0
9
74
1.22
0.25
1.3
1.3
—
—
—
0
0
23
266
0.86
0.25
1.1
1.1
1.2
3.0
u/ml
1.10
12
106
6
84
0.71
0.24
3.3
1.9
—
—
—
0
0
13
158
0.82
0.23
1.2
1.2
—
—
—
0
0
112
1057
1.06
0.23
1.0
1.0
—
—
—
0
0
17
143
1.19
0.23
1.1
1.2
—
—
—
0
0
7
92
0.76
0.22
1.1
1.5
—
—
—
0
0
12
146
0.82
0.22
1.6
1.4
0.9
1.0
g/l
0.09
12
146
0
11
0.00
0.21
0.0
3.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
2.5
—
0
11
21
182
1.16
0.21
1.5
1.6
—
—
—
0
0
21
182
1.16
0.21
1.5
1.6
—
—
—
0
0
21
182
1.16
0.21
1.5
1.6
—
—
—
0
0
223
2152
1.04
0.21
4.0
3.3
—
—
—
0
0
53
489
1.09
0.20
1.8
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
40
438
0.91
0.20
2.6
1.9
0.9
0.8
nmol/l
0.17
34
362
54
501
1.08
0.19
1.8
1.6
—
—
—
0
0
20
228
0.88
0.19
1.1
1.0
0.1
0.4
u/ml
—
5
64
125
1308
0.95
0.19
1.3
1.3
143.5
216.7
u/ml
1.22
114
1204
16
137
1.17
0.18
1.0
1.2
—
—
—
0
0
48
444
1.08
0.18
1.4
1.3
—
—
—
0
0
45
415
1.09
0.18
4.7
5.2
170.1
814.8
iu/ml
—
7
51
17
147
1.16
0.18
2.5
2.3
16.7
13.9
%
—
9
62
19
166
1.15
0.18
1.9
2.3
1.1
2.0
u/field
—
8
73
7
60
1.17
0.17
2.4
2.0
—
—
—
0
0
161
1671
0.96
0.17
4.6
3.8
1.2
1.2
mmol/l
0.12
151
1441
219
2125
1.03
0.16
2.2
2.1
—
—
—
0
0
35
321
1.09
0.16
2.1
1.9
1.8
1.7
mmol/l
0.29
35
315
16
139
1.15
0.16
1.3
1.2
—
—
—
0
0
8
71
1.13
0.16
1.1
1.5
—
—
—
0
0
10
119
0.84
0.15
1.0
1.1
—
—
—
0
0
18
159
1.13
0.15
2.0
2.3
687.8
627.7
ml
0.44
12
104
33
304
1.09
0.14
1.1
1.1
—
—
—
0
0
18
160
1.13
0.14
1.4
1.3
0.4
0.6
u/ml
0.24
12
71
8
98
0.82
0.13
1.0
1.0
—
—
—
0
0
47
444
1.06
0.11
1.4
1.3
—
—
—
0
0
320
3144
1.02
0.11
1.3
1.4
—
—
—
0
0
37
392
0.94
0.10
1.1
1.1
0.9
2.2
u/ml
0.75
14
178
5
46
1.09
0.09
4.6
2.7
—
—
—
0
0
62
597
1.04
0.08
1.4
1.3
—
—
—
0
0
6
74
0.81
0.07
1.3
1.2
114.8
109.9
%
—
6
64
634
6290
1.01
0.07
3.7
4.0
10.0
9.1
mg/mmol
0.07
391
3978
43
412
1.04
0.07
1.6
1.4
—
—
—
0
0
7
84
0.83
0.07
1.3
2.0
—
—
—
0
0
26
245
1.06
0.07
1.7
1.5
65.9
61.9
%
0.24
18
151
9
87
1.03
0.07
1.3
1.9
—
—
—
0
0
9
87
1.03
0.07
1.3
1.9
—
—
—
0
0
9
88
1.02
0.07
5.0
4.1
—
—
—
0
0
29
275
1.06
0.06
1.4
1.5
—
—
—
0
0
19
177
1.07
0.06
1.1
1.3
—
—
—
0
0
195
1921
1.02
0.06
2.1
2.0
—
—
—
0
0
11
99
1.11
0.06
2.8
3.8
—
—
—
0
0
37
355
1.04
0.06
1.5
1.5
—
—
—
0
0
63
648
0.97
0.06
1.3
1.4
—
—
—
0
0
22
233
0.94
0.05
1.3
1.3
—
—
—
0
0
48
464
1.04
0.05
9.4
4.4
5.2
5.1
kpa
0.33
48
459
41
395
1.04
0.05
1.4
1.3
210.8
253.6
u/ml
0.82
31
229
27
257
1.05
0.05
1.1
1.1
—
—
—
0
0
33
344
0.96
0.05
1.7
1.7
—
—
—
0
0
40
413
0.97
0.04
5.0
3.6
57.6
57.6
%
0.01
40
413
546
5431
1.01
0.04
1.7
1.7
1.4
1.4
mmol/l
0.27
474
4547
28
270
1.04
0.03
1.5
1.5
—
—
—
0
0
10
108
0.93
0.03
1.3
1.8
—
—
—
0
0
10
108
0.93
0.03
1.3
1.8
—
—
—
0
0
10
108
0.93
0.03
1.3
1.8
—
—
—
0
0
10
108
0.93
0.03
1.3
1.8
—
—
—
0
0
32
311
1.03
0.02
1.5
1.5
—
—
—
0
0
41
419
0.98
0.02
1.4
1.2
—
—
—
0
0
67
679
0.99
0.01
2.5
2.7
—
—
—
0
0
10
101
0.99
0.00
2.2
1.8
—
—
—
0
0
13
129
1.01
0.00
1.5
1.5
—
—
—
0
0
18
181
0.99
0.00
2.6
2.2
—
—
—
0
0
40
399
1.00
0.00
4.5
3.4
4.4
4.2
e9/l
0.11
40
399
12
116
1.03
0.00
1.2
1.4
—
—
—
0
0
11
108
1.02
0.00
1.0
1.0
—
—
—
0
0
14
138
1.01
0.00
1.3
1.2
—
—
—
0
0
17
172
0.99
0.00
1.2
1.1
—
—
—
0
0
172
1716
1.00
0.00
2.9
2.9
135.4
196.3
ng/l
1.91
152
1557
12
117
1.03
0.00
1.2
1.4
—
—
—
0
0
5
52
0.96
0.00
1.4
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
3.7
—
0
8
9
89
1.01
0.00
1.3
1.4
—
—
—
0
0
11
110
1.00
0.00
1.6
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
89
1.01
0.00
1.3
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
5.1
—
—
—
0
0
7
73
0.96
0.00
1.3
2.6
—
37721.9
—
0
12
0
7
0.00
0.00
0.0
6.1
—
—
—
0
0
11
110
1.00
0.00
1.6
1.6
—
—
—
0
0
9
89
1.01
0.00
1.3
1.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
8
86
0.93
0.00
1.3
1.1
175.9
208.6
iu/ml
—
8
86
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_BRAIN_CNS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BRAIN_CNS | 1.426 [1.28, 1.59] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.067 |
During the follow-up period (1.1.1998 — 31.12.2019), 1002 out of 6194 females with CD2_BENIGN_BRAIN_CNS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BRAIN_CNS | 1.535 [1.36, 1.73] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.01 |
During the follow-up period (1.1.1998 — 31.12.2019), 982 out of 5169 males with CD2_BENIGN_BRAIN_CNS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_BRAIN_CNS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.151% | 0.282% |
| 5 | 0.758% | 1.884% |
| 10 | 1.852% | 4.34% |
| 15 | 3.776% | 7.947% |
| 20 | 6.515% | 13.483% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BRAIN_CNS – Benign neoplasm of brain and other parts of central nervous system
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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