brain neoplasm: A neoplasm (disease) that involves the brain.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
525 |
4. Check minimum number of eventsNone |
525 |
5. Include endpointsNone |
525 |
6. Filter based on genotype QC (FinnGen only) |
502 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D33
- Name in latin
- Neoplasma benignum medullae spinalis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Spinal cord
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasms
- Neoplasms
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2876 | 1502 | 1358 |
| Only index persons | 2586 | 1356 | 1230 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.04 |
| Only index persons | 0.05 | 0.05 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 52.72 | 54.48 | 50.76 |
| Only index persons | 52.31 | 53.93 | 50.53 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 502 | 274 | 228 |
| Unadjusted period prevalence (%) | 0.10 | 0.10 | 0.10 |
| Median age at first event (years) | 54.43 | 53.85 | 55.13 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 525
- Matched controls
- 5250
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D33.45
ICD-10 Finland
Benign Schwannom in the nerve root of the spinal cord
+∞
307.7
283
*
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
+∞
225.8
200
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
19.2
155.0
133
91
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
38.3
106.7
67
20
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
22.7
87.6
66
33
D33.40
ICD-10 Finland
Benign glioma of the spinal cord (grade I)
+∞
86.9
81
*
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
+∞
85.8
80
*
D33.43
ICD-10 Finland
Spinal cord
+∞
83.6
78
*
D33.4
ICD-10 Finland
Benign neoplasm: Spinal cord
+∞
78.1
73
*
9560/0-C72.0
ICD-O-3
Schwannoma, NOS, of spinal cord
+∞
77.0
72
*
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
373.7
66.1
65
*
D33.47
ICD-10 Finland
Other benign neurofibromas in the nerve root of the spinal cord
+∞
61.7
58
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
15.9
49.9
44
30
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.4
48.8
160
479
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
11.0
46.7
52
52
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
16.6
46.5
40
26
D43.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Spinal cord
464.3
43.9
43
*
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
14.4
42.1
39
29
D33.41
ICD-10 Finland
Myxopapillary epndymoma of the spinal cord (grade I)
+∞
41.2
39
*
N03AX16
ATC
[U] pregabalin
3.5
41.1
202
788
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.6
40.9
114
298
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
6.0
36.0
69
130
D33.46
ICD-10 Finland
Benign neurofibroma in the nerve root of the spinal cord
+∞
35.8
34
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.4
32.6
92
241
N03AX12
ATC
[U] gabapentin; oral
3.4
32.3
150
554
N02BF01
ATC
gabapentin; oral
4.4
30.2
84
217
D36.1
ICD-10 Finland
Benign neoplasm: Peripheral nerves and autonomic nervous system
48.1
30.0
36
8
D33.42
ICD-10 Finland
Hemangioblastoma of the spinal cord
+∞
27.3
26
*
N02AX02
ATC
tramadol; systemic, rectal
2.6
26.3
285
1626
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
24.7
188
897
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
22.7
110
409
9391/3-C72.0
ICD-O-3
Ependymoma, NOS, of spinal cord
+∞
22.0
21
*
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
26.4
22.0
30
12
M03BX01
ATC
baclofen; systemic
7.8
21.9
31
42
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
+∞
21.0
20
*
9530/0-C70.1
ICD-O-3
Meningioma, NOS, of spinal meninges
218.3
20.7
21
*
XKD06
NOMESCO Finland
Physiologic investigation of micturition
5.6
20.0
39
74
9394/1-C72.0
ICD-O-3
Myxopapillary ependymoma of spinal cord
+∞
19.9
19
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.8
19.2
63
182
9560/0-C72.9
ICD-O-3
Schwannoma, NOS, of nervous system, NOS
+∞
18.9
18
*
NA2DG
NOMESCO Finland
Thoracal spine very extensive MRI examination with high intensity magnet
69.1
17.8
20
*
Q85.09
ICD-10 Finland
Unspecified neurofibromatosis
+∞
16.8
16
*
R4110
NOMESCO Finland
Physiotherapy
2.3
16.7
177
954
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
93.1
16.7
18
*
L28
ICPC
Limited function/disability (L)
2.6
16.6
113
498
Z31.5
ICD-10 Finland
Genetic counselling
4.0
15.6
46
123
2253A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Spinal cord
+∞
14.6
14
*
22530
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Spinal cord
+∞
14.6
14
*
Q85.01
ICD-10 Finland
Neurofibromatosis, type 2
+∞
14.6
14
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.0
13.7
64
230
SPAT1153
SPAT
Removal of sutures
2.1
13.4
190
1130
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
4.6
13.3
32
73
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.9
13.0
40
110
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.6
13.0
82
346
WX402
NOMESCO Finland
General anaesthesia
2.2
13.0
134
705
D33.30
ICD-10 Finland
Acoustic neuroma
23.2
13.0
18
8
M54.4
ICD-10 Finland
Lumbago with sciatica
2.3
13.0
116
575
AA1AD
NOMESCO Finland
CT of head and brain
2.1
12.9
160
904
M48.0
ICD-10 Finland
Spinal stenosis
2.6
12.6
81
345
C72.00
ICD-10 Finland
Malignant tumor of the spinal cord without histology
+∞
12.5
12
*
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
133.1
12.5
13
*
N06AX21
ATC
duloxetine; oral
2.6
12.5
82
353
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.4
12.3
101
482
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
12.8
12.2
21
17
M54.5
ICD-10 Finland
Low back pain
2.0
12.2
208
1313
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.8
12.1
67
264
XKD00
NOMESCO Finland
Uroflowmetry
2.4
12.1
97
458
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
10.9
11.9
22
21
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
3.0
11.6
53
188
9161/1-C72.0
ICD-O-3
Hemangioblastoma of spinal cord
+∞
11.5
11
*
C72.01
ICD-10 Finland
Malignant tumor of the spinal cord grade II glioma
+∞
11.5
11
*
Q85.0
ICD-10 Finland
Neurofibromatosis (nonmalignant)
+∞
11.5
11
*
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
35.9
11.3
14
*
G82.2
ICD-10 Finland
Paraplegia, unspecified
25.7
11.2
15
6
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.6
10.8
26
59
N02BF02
ATC
pregabalin; oral
3.1
10.7
46
157
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.6
10.6
65
270
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
10.5
81
375
D33.7
ICD-10 Finland
Benign neoplasm: Other specified parts of central nervous system
112.2
10.5
11
*
D33.14
ICD-10 Finland
Hemangioblastoma and cerebellum
+∞
10.4
10
*
D43.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other parts of central nervous system
+∞
10.4
10
*
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.8
10.4
53
200
R33
ICD-10 Finland
Retention of urine
2.9
10.3
50
183
ACB19
NOMESCO Finland
Excision of lesion of peripheral nerve other or unspecified
19.2
10.3
15
8
S18
ICPC
Laceration/cut
1.8
10.3
257
1808
ZXC40
NOMESCO Finland
Use of ultrasound
13.5
10.2
17
13
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
11.6
10.1
18
16
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.5
9.6
63
270
2312
FHL
Extirpation or destruction
101.8
9.4
10
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
9.4
123
699
C72.09
ICD-10 Finland
Malignant tumor of the spinal cord other histology
+∞
9.4
9
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
9.0
233
1636
N06AA09
ATC
amitriptyline; systemic
2.5
9.0
62
272
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
8.8
68
314
M03BX02
ATC
tizanidine; oral
1.8
8.7
329
2565
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.9
8.6
25
66
N18
ICPC
Paralysis/weakness
6.6
8.6
21
33
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
8.5
379
3085
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
8.5
242
1738
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
8.5
203
1388
NA7FT
NOMESCO Finland
Labeling lesion in spinal area with X-ray guidance
91.5
8.4
9
*
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
5.0
8.4
18
37
R4120
NOMESCO Finland
Occupational therapy
2.7
8.4
46
180
Q85.82
ICD-10 Finland
of Hipple-Lindau syndrome
+∞
8.4
8
*
N02BE01
ATC
paracetamol; systemic, rectal
2.4
8.2
473
4172
R1250
NOMESCO Finland
Evaluation of functional capability
4.4
8.0
20
47
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.2
8.0
31
100
N28
ICPC
Limited function/disability (N)
6.5
7.8
19
30
ZXH01
NOMESCO Finland
Procedure performed within operation theatre
45.7
7.7
9
*
UKC02
NOMESCO Finland
Cystoscopy
2.0
7.7
88
475
NA1DG
NOMESCO Finland
Cervical spine very extensive MRI examination with high intensity magnet
25.4
7.6
10
*
ZXD35
NOMESCO Finland
Usual procedure
3.5
7.5
25
73
G82.1
ICD-10 Finland
Spastic paraplegia
81.2
7.4
8
*
N75
ICPC
Benign neoplasm nervous system
81.2
7.4
8
*
2311
FHL
Resection
+∞
7.3
7
*
TAB00
NOMESCO Finland
Lumbar puncture
2.9
7.3
35
128
Z3226
NOMESCO Finland
Physiotherapist
1.9
7.2
100
576
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
7.1
191
1334
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.8
7.1
36
136
Z3231
NOMESCO Finland
Registered nurse
1.7
6.9
146
954
XKC03
NOMESCO Finland
Water cystometry
3.5
6.9
23
67
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
14.0
6.9
11
8
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
40.6
6.8
8
*
N76
ICPC
Neoplasm nervous system unspecified
40.6
6.8
8
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.0
6.7
75
401
A28
ICPC
Limited function/disability NOS
1.9
6.5
83
464
D48.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Peripheral nerves and autonomic nervous system
70.7
6.4
7
*
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
4.1
6.4
17
42
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.1
6.4
17
42
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.1
6.4
17
42
M79.6
ICD-10 Finland
Pain in limb
1.6
6.3
216
1594
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
18.3
6.3
9
5
1922A
ICD-9 Finland
Malignant neoplasm of other and unspecified parts of nervous system, Spinal cord
+∞
6.3
6
*
9421/1-C72.0
ICD-O-3
Pilocytic astrocytoma of spinal cord
+∞
6.3
6
*
9540/0-C72.0
ICD-O-3
Neurofibroma, NOS, of spinal cord
+∞
6.3
6
*
9161/1-C71.6
ICD-O-3
Hemangioblastoma of cerebellum, NOS
+∞
6.3
6
*
D16.6
ICD-10 Finland
Benign neoplasm: Vertebral column
+∞
6.3
6
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.9
6.2
82
463
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
27.0
6.2
8
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
6.2
52
248
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
2.3
6.2
47
215
ZXC95
NOMESCO Finland
Use of surgical navigator
7.8
6.2
13
17
A02BC02
ATC
pantoprazole; systemic
1.6
6.1
344
2842
TKC22
NOMESCO Finland
Catheterisation instruction
3.8
6.1
18
48
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
6.1
148
1000
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
12.7
6.1
10
8
N06AX16
ATC
venlafaxine; oral
1.9
6.1
78
437
M01AB55
ATC
diclofenac, combinations; oral
2.4
6.1
40
172
H02AB02
ATC
dexamethasone; systemic
2.0
6.0
66
350
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
47
29
17.70
56.21
1.6
1.8
—
—
—
0
0
122
470
3.08
23.76
8.5
10.3
1.49
1.27
mmol/l
0.30
96
385
209
1091
2.52
22.37
3.7
3.9
91.78
91.50
%
0.06
202
1068
299
1892
2.35
20.14
6.9
6.5
1.21
1.21
mmol/l
0.24
285
1717
315
2060
2.32
19.33
8.0
7.4
1.21
1.21
mmol/l
0.36
286
1755
194
1046
2.36
18.66
2.2
2.3
—
—
—
0
0
310
2043
2.26
18.27
2.8
2.6
—
—
—
0
0
358
2526
2.31
17.58
6.2
5.2
6.39
6.68
mmol/l
2.36
341
2363
224
1534
1.80
9.62
3.8
3.1
—
—
—
0
0
194
1289
1.80
9.11
2.4
2.1
210.52
192.57
u/l
0.15
187
1220
353
2798
1.80
8.90
6.2
4.3
968.40
1720.96
e6/l
—
5
47
124
722
1.94
8.79
2.8
2.6
0.64
1.11
e6/l
1.50
73
415
268
1980
1.72
8.51
13.8
12.7
1.21
1.24
inr
0.20
56
609
248
1796
1.72
8.45
5.2
4.8
35.77
35.92
g/l
0.15
234
1695
11
5
22.42
8.04
1.2
1.2
—
—
—
0
0
175
1173
1.74
7.72
3.6
3.0
0.38
0.41
e6/l
0.06
146
882
141
888
1.80
7.71
2.8
2.5
2.82
5.75
e6/l
2.53
126
797
94
523
1.97
7.53
9.5
8.0
104.65
104.11
mmol/l
0.54
94
523
114
678
1.87
7.48
3.0
2.8
1.76
2.35
e6/l
0.36
64
375
496
4505
2.83
7.40
21.3
15.9
3.93
3.97
mmol/l
2.26
491
4381
486
4379
2.48
7.25
18.3
13.8
21.66
23.26
mg/l
0.55
399
3430
15
19
8.09
7.15
1.9
1.3
—
—
—
0
0
94
539
1.91
6.86
6.4
6.4
—
—
—
0
0
384
3242
1.69
6.47
4.4
4.0
9.89
11.40
mm/h
1.61
361
2982
107
653
1.80
6.39
1.7
2.1
30.21
29.54
s
0.32
107
635
393
3361
1.67
6.05
8.6
7.6
73.20
78.20
u/l
2.90
382
3147
228
1753
1.53
5.31
2.3
2.2
77.44
76.26
nmol/l
0.24
214
1560
86
523
1.77
5.15
4.8
6.0
1.04
1.02
mmol/l
0.20
80
491
308
2535
1.52
5.15
9.1
9.5
4.06
4.09
e9/l
0.10
269
2225
382
3315
1.56
4.83
4.5
3.8
14.83
14.74
pmol/l
0.28
347
2996
213
1642
1.50
4.77
3.5
3.5
24.56
33.87
ng/l
0.79
136
1135
105
691
1.65
4.70
3.7
3.5
0.81
0.82
mmol/l
0.11
100
655
155
1136
1.52
4.35
5.0
3.8
0.00
0.01
estimate
0.50
49
390
274
2259
1.45
4.18
7.5
6.4
10.38
11.09
umol/l
1.02
264
2145
262
2149
1.44
4.07
4.7
3.5
0.00
0.01
estimate
0.50
46
381
34
164
2.15
4.02
5.6
4.0
1.05
1.36
mmol/l
2.12
34
159
258
2119
1.43
3.93
4.5
3.5
0.00
0.00
estimate
0.50
47
424
182
1417
1.44
3.66
4.0
3.4
2.37
2.35
mmol/l
0.97
166
1242
440
4025
1.58
3.62
5.4
4.5
1.83
2.20
mu/l
0.66
403
3676
108
764
1.52
3.51
3.3
2.8
2.45
2.45
mmol/l
0.23
94
677
50
292
1.79
3.45
1.6
1.7
—
—
—
0
0
254
2119
1.38
3.36
5.7
4.7
0.00
0.00
estimate
-0.00
48
403
104
739
1.51
3.30
1.4
1.3
21.46
38.56
iu/ml
1.81
30
234
154
1186
1.42
3.23
3.0
3.0
920.39
1069.25
ng/l
0.29
124
1006
50
305
1.71
2.99
2.7
2.5
18.35
15.54
au/ml
—
8
16
49
298
1.71
2.96
2.9
2.8
148.26
161.70
ng/l
0.13
43
266
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
24
117
2.10
2.81
1.8
2.5
0.42
0.36
u/ml
—
10
65
247
2095
1.34
2.76
6.4
6.1
28.33
27.90
%
0.22
234
1975
436
4043
1.46
2.72
5.7
5.7
38.30
39.70
mmol/mol
3.21
409
3755
97
708
1.45
2.69
1.3
1.3
3.24
12.07
u/ml
2.36
42
278
45
277
1.68
2.62
1.6
1.3
28.04
40.01
au/ml
—
5
20
243
2072
1.32
2.56
6.2
5.9
56.62
57.14
%
0.26
231
1955
122
939
1.39
2.51
5.7
3.7
1.02
1.02
kg/l
0.68
16
136
23
116
2.03
2.49
1.6
1.5
—
—
—
0
0
178
1459
1.33
2.45
4.0
3.3
35.38
31.36
u/l
0.47
173
1395
40
244
1.69
2.42
1.8
1.6
—
—
—
0
0
127
990
1.37
2.42
1.5
1.5
21.37
21.44
nmol/l
0.02
112
830
168
1368
1.34
2.41
3.4
2.5
51.78
61.99
u/l
1.83
157
1262
131
1027
1.37
2.41
2.3
2.0
3.04
3.12
mg/l
0.15
110
871
26
141
1.89
2.32
1.3
1.4
282.00
266.09
mu/l
0.20
26
130
9
28
3.25
2.31
1.1
1.2
—
—
—
0
0
9
29
3.14
2.23
1.3
1.0
—
—
—
0
0
201
1698
1.30
2.18
2.1
1.9
92.85
96.39
pmol/l
0.54
110
886
6
14
4.32
2.15
1.2
1.1
—
—
—
0
0
6
14
4.32
2.15
1.2
1.1
—
—
—
0
0
52
350
1.54
2.15
2.0
2.4
94.60
68.11
ml/min/173m2
0.44
20
148
6
15
4.03
2.04
1.2
1.2
—
—
—
0
0
6
15
4.03
2.04
1.2
1.3
—
—
—
0
0
507
4915
1.92
2.03
27.2
20.1
251.55
249.68
e9/l
0.27
500
4795
507
4915
1.92
2.03
27.9
20.3
40.33
40.52
%
0.31
485
4624
40
258
1.60
1.99
2.6
3.8
2.04
1.79
mmol/l
0.12
26
195
13
57
2.31
1.99
1.2
1.1
—
—
—
0
0
12
51
2.38
1.96
1.4
1.1
—
—
—
0
0
507
4919
1.90
1.96
27.2
20.1
4.53
4.53
e12/l
0.03
501
4786
507
4922
1.88
1.90
27.3
20.2
135.50
136.60
g/l
1.02
507
4851
51
353
1.49
1.87
2.6
2.5
4.75
7.27
ug/l
0.77
46
314
51
354
1.49
1.85
3.1
3.5
2.29
1.87
mmol/l
0.34
46
293
123
998
1.30
1.77
1.3
1.2
2.46
1.26
u/ml
0.35
37
276
24
140
1.75
1.75
1.3
1.2
—
—
—
0
0
443
4199
1.35
1.74
15.8
12.4
86.06
83.33
ml/min/173m2
1.69
388
3450
217
1893
1.25
1.72
2.7
2.7
99.81
127.28
ug/l
2.15
201
1735
0
47
0.00
1.71
0.0
1.3
—
—
—
0
0
19
104
1.86
1.69
1.2
1.5
—
—
—
0
0
314
2858
1.25
1.68
2.9
3.0
—
—
—
0
0
24
142
1.72
1.67
1.3
1.2
—
—
—
0
0
25
151
1.69
1.63
1.3
2.0
—
—
—
0
0
139
1158
1.27
1.62
4.8
4.2
19.81
21.04
%
0.46
74
518
5
15
3.35
1.52
1.2
1.1
—
—
—
0
0
133
1111
1.26
1.51
3.1
2.7
343.27
7461.90
umol/l
4.82
120
963
325
2991
1.23
1.48
4.1
3.2
45.39
48.43
u/l
0.45
317
2802
118
975
1.27
1.47
1.6
1.7
1.03
1.17
mg/l
0.27
88
741
447
4268
1.32
1.46
4.9
4.5
5.92
5.94
mmol/l
0.11
412
3907
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
5
16
3.14
1.44
1.8
2.0
103.80
117.13
%
—
5
16
9
39
2.33
1.43
1.1
1.3
—
—
—
0
0
405
3824
1.26
1.42
20.5
16.3
15.52
14.96
%
0.91
400
3769
486
4706
1.44
1.40
12.3
10.2
26.29
26.86
u/l
0.35
474
4536
11
53
2.10
1.39
1.4
1.1
—
—
—
0
0
58
437
1.37
1.39
4.0
3.3
—
—
—
0
0
189
1656
1.22
1.38
4.9
3.6
—
—
—
0
0
9
42
2.16
1.34
1.3
1.1
—
—
—
0
0
86
692
1.29
1.32
2.3
1.9
—
—
—
0
0
6
24
2.52
1.30
1.7
1.1
—
—
—
0
0
9
44
2.06
1.27
5.8
2.9
26.82
53.27
u/ml
—
9
44
20
125
1.62
1.19
1.3
1.1
4.78
12.24
u/ml
—
5
17
70
557
1.30
1.18
4.8
4.4
31.28
31.79
%
0.17
54
370
0
34
0.00
1.16
0.0
1.7
—
—
—
0
0
33
233
1.44
1.16
1.0
1.0
—
—
—
0
0
164
1445
1.20
1.10
5.4
4.7
2.17
2.22
ug/l
0.06
146
1302
5
21
2.39
1.09
1.0
1.0
—
—
—
0
0
18
114
1.60
1.04
2.4
1.7
4.49
6.30
iu/l
—
7
36
5
22
2.28
1.03
3.8
3.3
27.20
35.53
umol/l
—
5
15
9
47
1.93
1.02
2.0
2.0
—
—
—
0
0
9
48
1.89
1.01
5.6
3.9
—
—
—
0
0
11
61
1.82
0.99
1.0
1.2
8.50
1.39
u/ml
—
6
18
33
242
1.39
0.97
1.3
1.3
—
—
—
0
0
40
303
1.35
0.97
1.3
1.2
83.66
124.79
iu/ml
0.41
14
124
10
54
1.87
0.97
1.8
1.8
—
—
—
0
0
94
795
1.22
0.97
4.6
3.8
320.64
327.72
ng/l
0.01
78
600
10
173
0.57
0.96
1.2
1.6
—
—
—
0
0
24
167
1.46
0.93
1.7
1.9
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
28
2.16
0.91
1.7
1.2
—
—
—
0
0
8
47
1.71
0.81
1.1
1.2
—
—
—
0
0
456
4433
1.22
0.79
5.2
4.9
2.75
2.78
mmol/l
0.27
424
4078
0
24
0.00
0.79
0.0
1.6
—
—
—
0
0
0
24
0.00
0.79
0.0
1.6
—
—
—
0
0
21
148
1.44
0.79
1.1
2.3
—
—
—
0
0
8
48
1.68
0.79
2.0
1.9
—
—
—
0
0
0
26
0.00
0.78
0.0
2.2
—
—
—
0
0
19
133
1.44
0.74
1.4
1.4
—
—
—
0
0
68
574
1.21
0.74
2.3
2.3
21.29
22.72
%
0.43
60
500
49
399
1.25
0.74
3.6
2.6
31.83
35.53
u/l
0.24
42
336
21
151
1.41
0.72
1.9
1.8
—
—
—
0
0
96
839
1.18
0.72
3.2
2.9
0.63
0.72
ug/l
0.88
66
529
20
143
1.41
0.71
2.4
2.2
592.67
270.30
ug/l
0.36
20
131
58
484
1.22
0.71
2.5
1.8
—
—
—
0
0
5
27
1.86
0.68
1.2
1.4
1.65
1.59
g/l
—
5
27
29
223
1.32
0.68
3.5
1.8
—
—
—
0
0
77
664
1.19
0.68
2.4
2.3
13.51
13.29
umol/l
0.10
71
619
16
112
1.44
0.64
1.4
1.2
—
—
—
0
0
33
262
1.28
0.62
1.4
1.4
—
—
—
0
0
10
63
1.60
0.62
1.1
1.5
—
—
—
0
0
8
51
1.58
0.60
1.1
1.2
—
—
—
0
0
20
148
1.37
0.60
2.7
2.9
—
—
—
0
0
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
10
64
1.57
0.59
1.1
1.5
—
—
—
0
0
10
64
1.57
0.59
1.1
1.5
—
—
—
0
0
10
64
1.57
0.59
1.1
1.5
—
—
—
0
0
10
64
1.57
0.59
1.1
1.5
—
—
—
0
0
31
247
1.27
0.58
2.6
3.4
128.19
127.20
g/l
0.09
31
242
6
35
1.72
0.58
1.5
1.5
0.57
1.56
u/ml
—
6
20
6
36
1.67
0.57
1.2
1.7
1.00
0.97
g/l
—
6
36
11
73
1.52
0.56
1.8
1.4
—
—
—
0
0
11
73
1.52
0.56
1.8
1.4
—
—
—
0
0
10
65
1.55
0.56
1.1
1.5
—
—
—
0
0
446
4361
1.15
0.53
4.7
4.4
4.65
4.67
mmol/l
0.19
420
4038
10
66
1.53
0.53
1.0
1.2
3.00
4.12
u/ml
—
5
25
6
96
0.62
0.52
1.2
1.5
—
—
—
0
0
6
96
0.62
0.52
1.2
1.5
—
—
—
0
0
6
96
0.62
0.52
1.2
1.5
—
—
—
0
0
69
607
1.16
0.50
2.1
2.2
2.33
2.36
g/l
0.18
64
562
10
67
1.50
0.50
1.4
1.8
—
—
—
0
0
7
45
1.56
0.49
2.3
3.0
—
—
—
0
0
56
486
1.17
0.48
2.6
1.9
—
—
—
0
0
63
553
1.16
0.47
1.8
1.7
1.56
1.48
%
0.15
55
485
5
82
0.61
0.46
1.4
1.6
—
—
—
0
0
14
103
1.37
0.45
1.2
1.1
—
—
—
0
0
95
862
1.12
0.45
1.5
1.7
80000436.75
23045130.99
pmol/l
0.31
85
716
19
149
1.29
0.42
1.5
1.7
—
—
—
0
0
5
33
1.52
0.41
1.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
8
60
1.34
0.40
2.6
1.6
—
—
—
0
0
8
60
1.34
0.40
2.6
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
8.71
—
0
18
7
101
0.69
0.40
1.4
1.6
—
—
—
0
0
141
1320
1.09
0.38
3.5
3.9
3.75
9.91
mg/mmol
3.09
94
840
9
68
1.33
0.37
1.3
1.4
—
—
—
0
0
13
98
1.33
0.37
1.2
1.2
—
1.02
—
0
8
145
1361
1.09
0.37
3.3
3.1
7.75
7.74
mmol/l
0.01
125
1139
13
99
1.32
0.35
1.2
1.3
—
—
—
0
0
12
91
1.33
0.34
1.3
1.6
—
—
—
0
0
441
4341
1.10
0.32
4.7
4.4
1.47
1.46
mmol/l
0.18
410
3995
426
4190
1.09
0.30
4.2
4.0
1.32
1.29
mmol/l
0.37
394
3842
36
408
0.87
0.30
1.7
1.7
—
—
—
0
0
31
270
1.16
0.29
3.5
1.9
—
—
—
0
0
8
64
1.25
0.27
1.0
1.1
—
—
—
0
0
80
743
1.09
0.27
1.7
1.7
1290.47
1229.35
nmol/l
0.12
62
562
5
74
0.67
0.26
1.0
1.1
—
—
—
0
0
22
188
1.18
0.26
1.9
2.4
0.55
0.65
%
0.96
22
188
6
85
0.70
0.24
2.0
1.8
—
—
—
0
0
19
162
1.18
0.23
1.6
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
12
98
1.23
0.21
1.3
1.7
4255.14
10569.32
e6/l
—
7
71
15
126
1.20
0.21
1.5
1.4
213.33
295.07
ug/g
—
9
75
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
10
80
1.25
0.20
2.5
1.7
—
—
—
0
0
10
80
1.25
0.20
2.5
1.7
—
—
—
0
0
6
52
1.16
0.19
1.0
2.2
3.55
3.89
umol/l
—
6
36
7
61
1.15
0.17
1.0
1.0
—
—
—
0
0
77
807
0.95
0.15
1.7
1.5
—
—
—
0
0
9
83
1.09
0.14
2.0
1.6
—
—
—
0
0
12
103
1.17
0.14
1.1
1.2
—
—
—
0
0
124
1200
1.04
0.14
2.0
1.6
1.38
1.41
mmol/l
0.14
110
1010
13
113
1.15
0.13
1.4
1.3
—
—
—
0
0
12
105
1.15
0.11
1.8
1.8
—
—
—
0
0
5
46
1.09
0.09
2.6
1.8
—
—
—
0
0
10
113
0.88
0.08
2.5
1.7
—
—
—
0
0
50
521
0.96
0.08
3.1
2.0
—
—
—
0
0
5
63
0.79
0.08
1.0
1.1
—
—
—
0
0
5
63
0.79
0.08
2.0
1.7
—
—
—
0
0
6
70
0.86
0.07
1.5
1.7
—
—
—
0
0
66
639
1.04
0.07
1.5
1.4
—
—
—
0
0
6
75
0.80
0.07
3.0
2.9
—
814.11
u/ml
—
0
9
47
454
1.04
0.06
4.2
4.2
3.66
31.73
ug/l
0.97
37
382
46
476
0.96
0.06
3.0
1.8
—
—
—
0
0
14
132
1.06
0.02
1.7
1.4
—
—
—
0
0
10
94
1.07
0.01
1.1
1.4
—
—
—
0
0
10
94
1.07
0.01
2.1
1.5
—
—
—
0
0
12
114
1.05
0.00
1.2
1.4
—
—
—
0
0
20
194
1.03
0.00
3.0
3.4
25.64
25.09
mmol/l
0.28
20
189
11
114
0.96
0.00
2.4
1.7
—
—
—
0
0
10
103
0.97
0.00
2.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
65.67
—
0
6
6
64
0.94
-0.00
1.7
1.7
—
—
—
0
0
7
75
0.93
-0.00
8.4
5.5
416.71
377.69
umol/l
—
7
67
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.1
—
—
—
0
0
7
73
0.96
-0.00
1.9
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
14
140
1.00
-0.00
1.1
1.3
—
—
—
0
0
9
97
0.93
-0.00
1.3
1.3
—
—
—
0
0
5
57
0.88
-0.00
1.0
1.1
—
16.44
—
0
5
5
50
1.00
-0.00
1.6
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
78
0.90
-0.00
1.6
3.5
57.14
57.01
%
—
7
78
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_SPINAL_CORD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_SPINAL_CORD | 1.2 [0.99, 1.46] | 0.064 |
| Birth year | 0.996 [0.99, 1.0] | 0.315 |
During the follow-up period (1.1.1998 — 31.12.2019), 142 out of 1100 females with CD2_BENIGN_SPINAL_CORD died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_SPINAL_CORD | 1.165 [0.93, 1.46] | 0.183 |
| Birth year | 0.99 [0.98, 1.0] | 0.045 |
During the follow-up period (1.1.1998 — 31.12.2019), 140 out of 1023 males with CD2_BENIGN_SPINAL_CORD died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_SPINAL_CORD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.107% | 0.251% |
| 5 | 0.634% | 1.359% |
| 10 | 1.786% | 3.458% |
| 15 | 3.536% | 6.946% |
| 20 | 6.393% | 11.864% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_SPINAL_CORD – Benign neoplasm: Spinal cord
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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