brain neoplasm: A neoplasm (disease) that involves the brain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
500 |
4. Check minimum number of eventsNone |
500 |
5. Include endpointsNone |
500 |
6. Filter based on genotype QC (FinnGen only) |
500 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D33
- Name in latin
- Neoplasma benignum medullae spinalis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Spinal cord
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Spinal cord
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2876 | 1502 | 1358 |
| Only index persons | 2586 | 1356 | 1230 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.04 |
| Only index persons | 0.05 | 0.05 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 52.72 | 54.48 | 50.76 |
| Only index persons | 52.31 | 53.93 | 50.53 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 500 | 271 | 229 |
| Unadjusted period prevalence (%) | 0.10 | 0.09 | 0.10 |
| Median age at first event (years) | 54.11 | 53.44 | 54.90 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 450
- Matched controls
- 4500
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D33.45
ICD-10 Finland
Benign Schwannom in the nerve root of the spinal cord
+∞
286.0
243
*
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
3082.1
202.0
180
*
D33.40
ICD-10 Finland
Benign glioma of the spinal cord (grade I)
+∞
81.8
76
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
25.2
78.8
113
59
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
+∞
74.0
69
*
D33.43
ICD-10 Finland
Spinal cord
+∞
72.9
68
*
D33.4
ICD-10 Finland
Benign neoplasm: Spinal cord
+∞
70.7
66
*
9560/0-C72.0
ICD-O-3
Schwannoma, NOS, of spinal cord
+∞
70.7
66
*
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
86.0
54.5
60
8
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
299.6
53.4
53
*
D33.47
ICD-10 Finland
Other benign neurofibromas in the nerve root of the spinal cord
+∞
49.9
47
*
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
18.1
35.7
56
35
D43.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Spinal cord
375.0
35.5
35
*
D33.41
ICD-10 Finland
Myxopapillary epndymoma of the spinal cord (grade I)
+∞
34.8
33
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.3
31.3
138
424
N03AX16
ATC
pregabalin; oral
3.7
30.9
171
638
D33.46
ICD-10 Finland
Benign neurofibroma in the nerve root of the spinal cord
+∞
30.6
29
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
5.6
29.3
92
196
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
30.0
27.1
36
13
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
27.8
26.6
36
14
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
29.0
26.2
35
13
N03AX12
ATC
gabapentin; oral
3.9
25.9
123
396
D36.1
ICD-10 Finland
Benign neoplasm: Peripheral nerves and autonomic nervous system
91.8
23.9
26
*
D33.42
ICD-10 Finland
Hemangioblastoma of the spinal cord
+∞
23.1
22
*
N02AX02
ATC
tramadol; systemic, rectal
2.8
23.1
235
1278
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.7
20.9
75
182
9394/1-C72.0
ICD-O-3
Myxopapillary ependymoma of spinal cord
+∞
19.9
19
*
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
30.5
19.9
26
9
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
19.8
169
803
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
9.6
19.6
40
45
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
5.8
19.1
56
108
9530/0-C70.1
ICD-O-3
Meningioma, NOS, of spinal meninges
187.1
17.6
18
*
9391/3-C72.0
ICD-O-3
Ependymoma, NOS, of spinal cord
+∞
16.8
16
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
5.2
16.7
53
112
9560/0-C72.9
ICD-O-3
Schwannoma, NOS, of nervous system, NOS
+∞
15.7
15
*
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
+∞
15.7
15
*
L28
ICPC
Limited function/disability (L)
3.1
14.9
92
348
NA2DG
NOMESCO Finland
Thoracal spine very extensive MRI examination with high intensity magnet
58.7
14.9
17
*
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
154.8
14.5
15
*
XKD06
NOMESCO Finland
Physiologic investigation of micturition
7.3
14.2
34
50
M03BX01
ATC
baclofen; systemic
9.8
13.7
27
29
22530
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Spinal cord
+∞
13.6
13
*
Q85.09
ICD-10 Finland
Unspecified neurofibromatosis
144.2
13.5
14
*
ZXC40
NOMESCO Finland
Use of ultrasound
41.4
13.2
16
*
M54.5
ICD-10 Finland
Low back pain
2.2
12.7
165
932
D33.30
ICD-10 Finland
Acoustic neuroma
33.1
12.6
16
5
N02BE01
ATC
paracetamol; systemic, rectal
2.7
12.6
397
3307
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.5
12.5
60
188
SPAT1153
SPAT
Removal of sutures
2.1
11.9
169
986
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.5
11.9
57
179
WX402
NOMESCO Finland
General anaesthesia
2.5
11.6
97
438
2253A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Spinal cord
+∞
11.5
11
*
Q85.01
ICD-10 Finland
Neurofibromatosis, type 2
123.0
11.5
12
*
AA1AD
NOMESCO Finland
CT of head and brain
2.3
11.4
127
662
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
11.6
11.1
20
18
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.0
10.9
66
244
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.2
10.8
57
193
ACB19
NOMESCO Finland
Excision of lesion of peripheral nerve other or unspecified
61.5
10.7
12
*
9161/1-C72.0
ICD-O-3
Hemangioblastoma of spinal cord
+∞
10.5
10
*
C72.00
ICD-10 Finland
Malignant tumor of the spinal cord without histology
+∞
10.5
10
*
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
33.4
10.4
13
*
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
5.7
10.3
29
54
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
3.8
10.0
42
118
R4110
NOMESCO Finland
Physiotherapy
2.1
9.7
139
798
M48.0
ICD-10 Finland
Spinal stenosis
2.8
9.7
67
269
WX110
NOMESCO Finland
Local anesthesy
1.9
9.7
316
2466
C72.01
ICD-10 Finland
Malignant tumor of the spinal cord grade II glioma
+∞
9.4
9
*
D33.14
ICD-10 Finland
Hemangioblastoma and cerebellum
+∞
9.4
9
*
D33.7
ICD-10 Finland
Benign neoplasm: Other specified parts of central nervous system
+∞
9.4
9
*
C72.09
ICD-10 Finland
Malignant tumor of the spinal cord other histology
+∞
9.4
9
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.5
9.3
79
358
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.7
9.1
63
254
Z31.5
ICD-10 Finland
Genetic counselling
3.7
9.0
38
108
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
9.0
110
590
G82.2
ICD-10 Finland
Paraplegia, unspecified
24.6
8.9
12
5
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.8
8.8
28
61
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
14.4
8.7
14
10
N06AX21
ATC
duloxetine; oral
2.7
8.7
61
247
M54.4
ICD-10 Finland
Lumbago with sciatica
2.3
8.6
84
408
D43.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other parts of central nervous system
91.7
8.4
9
*
2312
FHL
Extirpation or destruction
+∞
8.4
8
*
N18
ICPC
Paralysis/weakness
7.8
8.2
18
24
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
8.1
138
842
S18
ICPC
Laceration/cut
1.8
7.7
197
1371
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
18.7
7.6
11
6
XKD00
NOMESCO Finland
Uroflowmetry
2.2
7.5
81
411
Q85.0
ICD-10 Finland
Neurofibromatosis (nonmalignant)
81.4
7.4
8
*
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
11.1
7.3
13
12
N75
ICPC
Benign neoplasm nervous system
+∞
7.3
7
*
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
+∞
7.3
7
*
UKC02
NOMESCO Finland
Cystoscopy
2.2
7.2
77
389
TPH07
NOMESCO Finland
Cathetrisation of artery
2.5
7.2
56
243
R4120
NOMESCO Finland
Occupational therapy
3.1
7.1
38
131
M03BX02
ATC
tizanidine; oral
1.7
7.1
275
2150
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.5
7.1
57
250
N06AA09
ATC
amitriptyline; systemic
2.5
6.9
53
226
R33
ICD-10 Finland
Retention of urine
2.8
6.8
41
153
N02AA05
ATC
oxycodone; systemic
2.2
6.8
68
333
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
40.7
6.8
8
*
TAB00
NOMESCO Finland
Lumbar puncture
3.5
6.7
30
91
N28
ICPC
Limited function/disability (N)
8.0
6.7
14
18
L03
ICPC
Low back symptom/complaint
1.9
6.6
110
658
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
6.6
168
1156
A02BC02
ATC
pantoprazole; systemic
1.7
6.6
271
2136
A06AD11
ATC
lactulose; oral
2.2
6.5
66
324
M54.2
ICD-10 Finland
Cervicalgia
2.8
6.5
41
156
G95.9
ICD-10 Finland
Disease of spinal cord, unspecified
70.8
6.4
7
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
6.3
190
1365
9421/1-C72.0
ICD-O-3
Pilocytic astrocytoma of spinal cord
+∞
6.3
6
*
Q85.82
ICD-10 Finland
of Hipple-Lindau syndrome
+∞
6.3
6
*
NA1DG
NOMESCO Finland
Cervical spine very extensive MRI examination with high intensity magnet
27.1
6.2
8
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
47
27
19.11
58.24
1.6
1.8
—
—
—
0
0
120
447
3.22
24.98
8.6
10.3
1.5
1.3
mmol/l
0.36
94
361
289
1807
2.42
20.51
7.1
6.3
1.2
1.2
mmol/l
0.42
274
1628
305
1970
2.41
19.87
8.2
7.2
1.2
1.2
mmol/l
0.47
274
1668
294
1934
2.26
17.44
4.2
4.0
—
—
—
0
0
182
992
2.31
16.94
2.2
2.3
—
—
—
0
0
341
2405
2.31
16.81
6.4
5.1
6.4
6.7
mmol/l
1.90
323
2249
15
19
8.11
11.06
1.9
1.3
—
—
—
0
0
220
1467
1.89
10.76
3.9
3.1
—
—
—
0
0
187
1221
1.85
9.49
2.4
2.1
215.1
194.2
u/l
0.17
180
1158
340
2667
1.86
9.34
6.4
4.3
968.4
1758.3
e6/l
—
5
46
122
696
2.00
9.29
2.8
2.6
0.7
1.1
e6/l
1.59
72
398
241
1716
1.78
9.06
5.3
4.7
35.7
35.9
g/l
0.19
227
1613
173
1118
1.84
8.98
3.6
3.0
0.4
0.4
e6/l
0.11
144
833
11
5
22.44
8.04
1.2
1.2
—
—
—
0
0
111
650
1.91
7.70
3.0
2.8
1.7
2.4
e6/l
0.50
62
356
92
514
1.97
7.31
6.5
6.4
—
—
—
0
0
103
619
1.84
6.52
1.7
2.0
30.2
29.6
s
0.25
103
603
461
4167
2.36
6.49
19.0
13.6
21.6
23.1
mg/l
0.52
384
3264
365
3084
1.68
6.11
4.5
4.0
10.0
11.4
mm/h
1.31
343
2833
105
649
1.78
6.03
3.7
3.5
0.8
0.8
mmol/l
0.10
100
614
300
2421
1.60
6.00
9.3
9.4
4.1
4.1
e9/l
0.03
263
2121
85
500
1.84
5.72
4.8
5.5
1.0
1.0
mmol/l
0.30
79
468
218
1658
1.56
5.47
2.4
2.2
77.7
76.5
nmol/l
0.25
205
1475
154
1082
1.61
5.42
5.1
3.8
0.0
0.0
estimate
0.00
49
363
259
2051
1.55
5.39
4.8
3.5
0.0
0.0
estimate
0.50
46
356
372
3207
1.62
5.25
8.9
7.5
73.5
78.1
u/l
2.47
364
2997
254
2016
1.53
5.15
4.5
3.5
0.0
0.0
estimate
0.00
44
368
205
1556
1.54
5.10
3.6
3.5
24.6
34.4
ng/l
0.82
133
1071
365
3155
1.58
4.86
4.6
3.8
14.8
14.7
pmol/l
0.31
333
2849
250
2022
1.47
4.37
5.7
4.7
0.0
0.0
estimate
0.00
48
374
178
1358
1.48
4.12
4.0
3.4
2.4
2.4
mmol/l
0.62
161
1180
50
277
1.89
4.06
1.6
1.6
—
—
—
0
0
262
2165
1.44
3.95
7.7
6.3
10.3
11.1
umol/l
1.21
252
2051
102
709
1.55
3.62
1.4
1.3
21.7
37.7
iu/ml
1.57
29
218
418
3820
1.57
3.49
5.5
4.5
1.8
2.2
mu/l
0.60
384
3486
104
738
1.52
3.35
3.3
2.8
2.4
2.4
mmol/l
0.09
90
653
149
1144
1.43
3.21
3.0
3.1
947.1
1049.1
ng/l
0.18
120
974
121
897
1.46
3.13
5.8
3.7
1.0
1.0
kg/l
0.69
16
129
48
286
1.75
3.12
3.0
2.7
151.5
159.0
ng/l
0.06
42
255
48
287
1.74
3.08
2.7
2.5
23.3
14.3
au/ml
—
6
12
23
107
2.20
3.01
1.6
1.4
—
—
—
0
0
128
970
1.43
2.94
2.3
2.0
3.1
3.1
mg/l
0.10
107
820
40
233
1.78
2.82
1.8
1.5
—
—
—
0
0
9
23
3.96
2.78
1.1
1.2
—
—
—
0
0
124
948
1.41
2.69
1.5
1.5
21.6
21.5
nmol/l
0.02
109
793
416
3855
1.47
2.66
5.7
5.7
38.3
39.7
mmol/mol
3.20
391
3583
9
25
3.65
2.58
1.3
1.0
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
22
109
2.07
2.50
1.9
2.5
0.4
0.4
u/ml
—
9
60
194
1611
1.33
2.48
2.1
1.9
93.3
96.3
pmol/l
0.42
105
835
51
331
1.60
2.44
2.0
2.4
96.1
68.3
ml/min/173m2
0.44
19
142
170
1388
1.34
2.43
4.0
3.3
35.8
31.5
u/l
0.48
165
1328
25
133
1.93
2.35
1.4
1.4
289.8
268.1
mu/l
0.28
25
122
51
335
1.58
2.33
3.1
3.5
2.4
1.9
mmol/l
0.42
44
264
6
13
4.66
2.27
1.2
1.2
—
—
—
0
0
6
13
4.66
2.27
1.2
1.2
—
—
—
0
0
91
679
1.42
2.25
1.3
1.3
3.3
11.7
u/ml
2.14
41
265
12
48
2.54
2.20
1.4
1.1
—
—
—
0
0
12
48
2.54
2.20
1.2
1.1
—
—
—
0
0
6
14
4.32
2.15
1.2
1.3
—
—
—
0
0
6
14
4.32
2.15
1.2
1.2
—
—
—
0
0
158
1300
1.31
2.10
3.5
2.5
51.8
57.2
u/l
1.54
147
1197
58
405
1.49
2.03
4.0
3.2
—
—
—
0
0
19
98
1.98
1.98
1.2
1.3
—
—
—
0
0
186
1581
1.28
1.90
4.9
3.6
—
—
—
0
0
135
1104
1.31
1.85
4.8
4.3
20.1
20.9
%
0.26
74
491
23
130
1.81
1.85
1.3
1.2
—
—
—
0
0
207
1790
1.27
1.83
2.7
2.6
102.2
124.5
ug/l
1.62
192
1638
482
4679
1.84
1.79
28.1
20.0
135.4
136.6
g/l
1.19
482
4611
23
132
1.78
1.77
1.3
1.2
—
—
—
0
0
421
3982
1.36
1.75
16.1
12.4
85.9
83.1
ml/min/173m2
1.72
372
3269
49
342
1.48
1.74
2.7
2.5
4.8
6.7
ug/l
0.52
44
304
37
243
1.56
1.73
2.7
3.7
2.3
1.8
mmol/l
0.29
24
185
116
939
1.31
1.71
1.3
1.2
2.4
1.3
u/ml
0.29
34
255
5
14
3.60
1.62
1.2
1.1
—
—
—
0
0
297
2702
1.24
1.61
2.9
3.0
—
—
—
0
0
6
20
3.02
1.58
1.7
1.2
—
—
—
0
0
11
50
2.23
1.58
1.4
1.1
—
—
—
0
0
24
145
1.69
1.57
1.3
2.1
—
—
—
0
0
84
658
1.33
1.56
2.3
1.9
—
—
—
0
0
113
925
1.29
1.53
1.7
1.8
1.1
1.2
mg/l
0.16
84
702
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
5
15
3.36
1.52
1.8
2.1
103.8
115.9
%
—
5
15
0
44
0.00
1.52
0.0
1.3
—
—
—
0
0
309
2835
1.24
1.50
4.1
3.1
46.0
48.8
u/l
0.38
303
2658
9
37
2.46
1.48
1.1
1.3
—
—
—
0
0
9
39
2.33
1.43
1.3
1.1
—
—
—
0
0
126
1057
1.26
1.39
3.1
2.7
344.2
7616.3
umol/l
4.60
114
903
8
161
0.49
1.38
1.3
1.6
—
—
—
0
0
9
41
2.22
1.37
5.8
3.0
26.8
54.6
u/ml
—
9
41
426
4073
1.31
1.35
4.9
4.5
5.9
5.9
mmol/l
0.14
395
3725
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
24
2.52
1.30
1.7
1.2
—
—
—
0
0
462
4476
1.42
1.29
12.6
10.2
26.1
26.9
u/l
0.50
451
4314
6
25
2.42
1.24
16.8
8.2
0.6
0.6
mmol/l
—
6
25
18
109
1.68
1.20
2.4
1.7
4.5
6.5
iu/l
—
7
34
21
133
1.60
1.19
1.1
2.4
2.8
3.1
g/l
0.70
14
108
11
57
1.95
1.18
1.0
1.2
8.5
1.4
u/ml
—
6
17
10
51
1.98
1.12
1.8
1.8
—
—
—
0
0
5
21
2.39
1.09
1.0
1.0
—
—
—
0
0
5
21
2.39
1.09
3.8
3.3
27.2
34.9
umol/l
—
5
14
18
113
1.62
1.07
1.3
1.1
4.8
13.6
u/ml
—
5
14
39
289
1.38
1.07
1.3
1.2
83.7
124.8
iu/ml
0.41
14
116
156
1375
1.20
1.06
5.5
4.8
2.2
2.2
ug/l
0.08
140
1239
31
221
1.43
1.05
1.0
1.0
—
—
—
0
0
9
46
1.97
1.04
5.6
4.0
—
—
—
0
0
20
132
1.54
0.98
1.2
2.4
8.8
10.3
g/l
0.94
14
117
0
30
0.00
0.97
0.0
1.7
—
—
—
0
0
31
225
1.40
0.97
1.3
1.3
—
—
—
0
0
20
133
1.52
0.96
2.4
2.2
592.7
277.5
ug/l
0.35
20
122
66
538
1.26
0.95
2.3
2.2
21.2
22.7
%
0.45
58
468
23
159
1.47
0.93
1.8
1.8
—
—
—
0
0
65
531
1.26
0.92
4.8
4.4
31.4
31.8
%
0.12
50
352
57
460
1.27
0.90
2.6
1.8
—
—
—
0
0
21
144
1.48
0.88
1.1
2.3
—
—
—
0
0
21
144
1.48
0.88
1.1
2.3
3.2
3.6
g/l
1.40
14
107
21
144
1.48
0.88
1.1
2.3
6.4
7.3
g/l
1.88
14
112
33
247
1.36
0.88
1.4
1.4
—
—
—
0
0
90
767
1.21
0.87
4.7
3.8
337.6
262.0
ng/l
0.14
74
579
75
628
1.23
0.86
2.4
2.2
13.4
13.2
umol/l
0.08
69
580
20
137
1.48
0.85
2.7
2.8
—
—
—
0
0
63
519
1.24
0.84
1.8
1.7
1.6
1.5
%
0.17
55
454
48
383
1.28
0.83
3.6
2.5
31.8
36.1
u/l
0.28
42
321
18
122
1.49
0.81
1.6
2.2
98.9
90.1
%
1.01
18
117
8
47
1.71
0.81
2.0
1.8
—
—
—
0
0
16
106
1.53
0.80
1.4
1.2
—
—
—
0
0
6
33
1.83
0.79
1.2
1.2
—
—
—
0
0
6
33
1.83
0.79
1.5
1.5
0.6
0.4
u/ml
—
6
16
0
25
0.00
0.79
0.0
2.2
—
—
—
0
0
8
48
1.68
0.79
1.1
1.2
—
—
—
0
0
18
123
1.48
0.78
1.4
1.4
—
—
—
0
0
10
59
1.71
0.76
1.1
1.3
—
—
—
0
0
56
462
1.24
0.75
2.6
1.9
—
—
—
0
0
31
237
1.33
0.74
2.6
3.3
128.2
127.3
g/l
0.08
31
232
10
60
1.68
0.72
1.1
1.3
—
—
—
0
0
10
60
1.68
0.72
1.1
1.3
—
—
—
0
0
10
60
1.68
0.72
1.1
1.3
—
—
—
0
0
10
60
1.68
0.72
1.1
1.3
—
—
—
0
0
92
801
1.18
0.72
3.3
2.9
0.6
0.7
ug/l
0.82
66
502
27
204
1.34
0.70
3.7
1.8
—
—
—
0
0
363
3488
1.15
0.69
22.2
16.8
13.7
13.7
%
0.34
357
3426
433
4217
1.20
0.69
5.2
4.9
2.7
2.8
mmol/l
0.23
405
3878
20
144
1.41
0.69
1.9
1.7
—
—
—
0
0
10
61
1.65
0.69
1.1
1.3
—
—
—
0
0
11
69
1.61
0.69
1.8
1.4
—
—
—
0
0
11
69
1.61
0.69
1.8
1.4
—
—
—
0
0
7
42
1.68
0.68
2.3
2.4
—
—
—
0
0
67
572
1.20
0.66
2.2
2.2
2.3
2.4
g/l
0.29
62
528
10
62
1.63
0.65
1.0
1.1
3.0
4.0
u/ml
—
5
22
10
63
1.60
0.62
1.4
1.8
—
—
—
0
0
5
30
1.67
0.61
1.0
1.5
1.1
1.0
g/l
—
5
30
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
19
141
1.36
0.57
1.5
1.7
—
—
—
0
0
14
98
1.44
0.57
1.3
1.1
—
—
—
0
0
5
89
0.56
0.56
1.2
1.5
—
—
—
0
0
5
89
0.56
0.56
1.2
1.5
—
—
—
0
0
5
89
0.56
0.56
1.2
1.5
—
—
—
0
0
13
91
1.44
0.53
2.5
2.7
8.6
8.0
kpa
0.59
13
82
424
4150
1.14
0.47
4.7
4.4
4.6
4.7
mmol/l
0.20
400
3844
12
85
1.42
0.47
1.3
1.6
—
—
—
0
0
13
94
1.39
0.46
1.3
1.3
—
—
—
0
0
91
825
1.13
0.44
1.5
1.7
83951051.7
7321080.8
pmol/l
0.44
81
683
394
3847
1.11
0.43
20.9
14.7
39.4
40.4
%
1.09
282
2812
6
93
0.64
0.42
1.5
1.6
—
—
—
0
0
19
149
1.29
0.42
1.6
1.6
—
—
—
0
0
5
32
1.57
0.42
1.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
8.7
—
0
18
8
61
1.32
0.39
1.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
78
709
1.12
0.37
1.7
1.7
1304.6
1238.6
nmol/l
0.13
61
535
6
45
1.34
0.34
1.2
1.2
—
—
—
0
0
29
248
1.18
0.32
3.7
1.9
—
—
—
0
0
12
93
1.30
0.30
1.3
1.7
4255.1
10223.9
e6/l
—
7
66
12
93
1.30
0.30
1.2
1.2
—
1.0
—
0
7
137
1299
1.08
0.28
3.3
3.0
7.7
7.7
mmol/l
0.02
119
1081
8
64
1.25
0.27
1.4
1.3
—
—
—
0
0
34
384
0.88
0.27
1.6
1.7
—
—
—
0
0
133
1262
1.07
0.27
3.5
4.0
3.9
9.3
mg/mmol
2.49
90
801
419
4131
1.09
0.26
4.7
4.4
1.5
1.5
mmol/l
0.06
392
3802
405
3988
1.08
0.26
4.2
4.0
1.3
1.3
mmol/l
0.67
376
3656
5
71
0.70
0.26
1.0
1.1
—
—
—
0
0
9
75
1.20
0.25
2.0
1.7
—
—
—
0
0
12
96
1.26
0.24
1.8
1.7
—
—
—
0
0
13
106
1.23
0.23
1.4
1.2
—
—
—
0
0
120
1144
1.06
0.22
2.0
1.6
1.4
1.4
mmol/l
0.03
108
963
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
2.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
7
59
1.19
0.18
1.0
1.1
—
—
—
0
0
6
79
0.76
0.15
2.0
1.7
—
—
—
0
0
46
430
1.08
0.15
4.2
4.2
3.7
32.6
ug/l
0.95
36
363
64
609
1.06
0.13
1.5
1.4
—
—
—
0
0
52
493
1.06
0.12
31.6
19.5
1.4
1.2
inr
—
8
71
73
759
0.96
0.11
1.7
1.5
—
—
—
0
0
5
44
1.14
0.10
3.0
1.8
—
—
—
0
0
5
44
1.14
0.10
1.6
1.2
—
—
—
0
0
6
57
1.05
0.08
1.7
1.7
—
—
—
0
0
5
60
0.83
0.08
1.0
1.1
—
—
—
0
0
10
88
1.14
0.08
1.1
1.3
—
—
—
0
0
47
490
0.95
0.08
3.1
2.0
—
—
—
0
0
7
65
1.08
0.08
1.9
1.7
—
—
—
0
0
11
98
1.13
0.07
1.1
1.2
—
—
—
0
0
20
186
1.08
0.07
3.0
3.4
25.6
24.9
mmol/l
0.39
20
181
12
108
1.11
0.07
1.3
1.4
—
—
—
0
0
12
132
0.91
0.06
1.2
1.2
—
—
—
0
0
10
90
1.11
0.05
2.1
1.5
—
—
—
0
0
43
444
0.97
0.05
2.9
1.8
—
—
—
0
0
10
107
0.93
0.02
2.7
2.5
25.6
25.1
mmol/l
—
10
92
12
127
0.94
0.01
1.7
1.4
—
—
—
0
0
10
106
0.94
0.01
2.5
1.7
—
—
—
0
0
10
106
0.94
0.01
2.5
1.7
—
—
—
0
0
10
97
1.03
0.00
2.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
4.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
65.7
—
0
6
7
69
1.01
0.00
8.4
5.6
416.7
380.5
umol/l
—
7
61
6
62
0.97
0.00
1.5
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
9
89
1.01
0.00
1.3
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
0.00
2.0
1.8
—
—
—
0
0
6
69
0.87
0.00
3.0
2.9
—
814.1
u/ml
—
0
9
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_SPINAL_CORD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_SPINAL_CORD | 1.2 [0.99, 1.46] | 0.064 |
| Birth year | 0.996 [0.99, 1.0] | 0.315 |
During the follow-up period (1.1.1998 — 31.12.2019), 142 out of 1100 females with CD2_BENIGN_SPINAL_CORD died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_SPINAL_CORD | 1.165 [0.93, 1.46] | 0.183 |
| Birth year | 0.99 [0.98, 1.0] | 0.045 |
During the follow-up period (1.1.1998 — 31.12.2019), 140 out of 1023 males with CD2_BENIGN_SPINAL_CORD died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_SPINAL_CORD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.107% | 0.251% |
| 5 | 0.634% | 1.359% |
| 10 | 1.786% | 3.458% |
| 15 | 3.536% | 6.946% |
| 20 | 6.393% | 11.864% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_SPINAL_CORD – Benign neoplasm: Spinal cord
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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