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Benign neoplasm: Brain, infratentorial

DOID EFO Endpoint Browser PheWeb

CD2_BENIGN_BRAIN_INFRATENT

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D33.1
  • Cause of death: ICD-10 — D33.1

2 out of 7 registries used, show all original rules.

208

4. Check minimum number of events

None

208

5. Include endpoints

None

208

6. Filter based on genotype QC (FinnGen only)

208

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D33
Name in latin
Neoplasma benignum cerebri infratentoriale

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1554 828 719
Only index persons 1386 743 643
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.03 0.03 0.02
Median age at first event (years)
Whole population 44.15 46.77 40.95
Only index persons 43.19 45.75 40.23

-FinnGen-

Key figures

All Female Male
Number of individuals 208 126 82
Unadjusted period prevalence (%) 0.04 0.04 0.04
Median age at first event (years) 47.97 46.83 49.72

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
185
Matched controls
1851
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
700.4
111.0
99
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
32.9
76.2
106
72
D33.10
ICD-10 Finland
Benign pilosytic astrocytoma of brain stem
+∞
64.4
58
*
D33.14
ICD-10 Finland
Hemangioblastoma and cerebellum
+∞
55.0
50
*
9161/1-C71.6
ICD-O-3
Hemangioblastoma of cerebellum, NOS
+∞
41.2
38
*
D33.15
ICD-10 Finland
Another benign tumor of the cerebellum
+∞
40.1
37
*
D33.11
ICD-10 Finland
Brain stem
+∞
36.7
34
*
D33.12
ICD-10 Finland
Cerebellum
+∞
32.2
30
*
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
+∞
28.9
27
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
27.0
28.4
39
18
C71.60
ICD-10 Finland
Malignant tumor of cerebellum without histology
+∞
27.8
26
*
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
47.8
26.8
32
8
D33.1
ICD-10 Finland
Benign neoplasm: Brain, infratentorial
+∞
21.2
20
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
9.0
21.1
47
67
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
5.6
19.4
65
163
9421/1-C71.6
ICD-O-3
Pilocytic astrocytoma of cerebellum, NOS
+∞
18.0
17
*
G91.1
ICD-10 Finland
Obstructive hydrocephalus
99.1
16.9
18
*
H02AB02
ATC
dexamethasone; systemic
5.8
14.9
45
97
AA1AD
NOMESCO Finland
CT of head and brain
3.8
13.6
71
262
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
13.0
12.7
22
19
D33.17
ICD-10 Finland
Fourth ventricle
+∞
12.6
12
*
R51.80
ICD-10 Finland
Headache
4.0
12.1
54
172
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
69.4
11.8
13
*
H53.2
ICD-10 Finland
Diplopia
11.7
11.6
21
20
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
21.7
11.3
16
8
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.7
10.9
54
187
AAF00
NOMESCO Finland
Ventriculostomy
42.5
10.1
12
*
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
42.5
10.1
12
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
18.0
10.1
15
9
XA800
NOMESCO Finland
Neuropsychological investigation
6.1
9.6
26
48
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
105.1
9.5
10
*
D33.42
ICD-10 Finland
Hemangioblastoma of the spinal cord
+∞
9.4
9
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
9.4
72
333
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
94.1
8.5
9
*
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
94.1
8.5
9
*
Q85.82
ICD-10 Finland
of Hipple-Lindau syndrome
+∞
8.4
8
*
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
15.4
8.3
13
9
XCK00
NOMESCO Finland
Perimetry
4.9
7.8
25
57
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
46.9
7.8
9
*
G91.0
ICD-10 Finland
Communicating hydrocephalus
46.9
7.8
9
*
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
46.9
7.8
9
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.7
7.4
58
268
D32.05
ICD-10 Finland
Cerebral meninges
+∞
7.3
7
*
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
23.5
6.7
9
*
N03AF01
ATC
carbamazepine; oral, rectal
7.3
6.7
15
22
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
15.0
6.5
10
7
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
72.2
6.5
7
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
11.6
6.4
11
10
C71.69
ICD-10 Finland
Malignant tumor of the cerebellum other or unspecified histology
+∞
6.3
6
*
9380/3-C71.9
ICD-O-3
Glioma, malignant of brain, NOS
+∞
6.3
6
*
AAF50
NOMESCO Finland
Third ventriculostomy
+∞
6.3
6
*
C71.6
ICD-10 Finland
Malignant neoplasm: Cerebellum
+∞
6.3
6
*
G93.0
ICD-10 Finland
Cerebral cysts
+∞
6.3
6
*
N76
ICPC
Neoplasm nervous system unspecified
+∞
6.3
6
*
D43.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, unspecified
27.7
6.3
8
*
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
13.1
6.2
10
8
R4110
NOMESCO Finland
Physiotherapy
2.4
6.1
61
318

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
20
17
12.91
19.87
3.3
1.2
—
—
—
0
0
54
167
4.02
15.71
7.1
11.3
0.7
1.4
mmol/l
0.72
41
137
14
13
11.47
12.99
2.8
3.4
—
—
—
0
0
17
21
8.73
12.94
4.2
3.7
1.4
3.3
nmol/l
1.45
17
21
21
35
6.56
12.39
2.6
2.6
—
—
—
0
0
126
741
2.78
11.59
7.3
7.6
1.2
1.2
mmol/l
1.77
118
675
97
522
2.61
10.34
2.5
2.5
—
—
—
0
0
129
807
2.58
9.87
5.7
8.4
1.2
1.2
mmol/l
1.37
116
695
39
134
3.35
9.43
5.7
10.1
24.0
25.0
mmol/l
1.31
39
134
147
1004
2.58
8.94
6.1
5.6
6.4
6.6
mmol/l
0.41
142
919
20
44
4.92
8.80
2.3
2.2
24.3
3.4
e6/l
0.61
13
35
20
44
4.92
8.80
2.5
2.3
95.7
289.2
e6/l
0.59
13
38
14
24
6.18
7.96
4.1
1.6
—
—
—
0
0
39
148
3.01
7.94
1.4
1.4
—
—
—
0
0
38
151
2.86
7.10
5.4
10.3
—
—
—
0
0
25
79
3.46
6.82
4.3
15.8
—
—
—
0
0
105
688
2.06
6.14
2.4
2.0
—
—
—
0
0
11
20
5.75
5.87
2.9
3.6
—
—
—
0
0
10
9
11.59
5.86
2.2
5.0
58.7
107.1
nmol/l
—
10
9
97
626
2.03
5.83
4.6
7.0
1.2
1.2
inr
0.06
24
195
41
198
2.33
5.09
6.7
8.5
105.0
104.0
mmol/l
0.81
41
191
10
22
4.72
4.35
3.9
1.6
—
—
nmol/l
—
0
0
97
687
1.77
3.96
4.0
5.5
36.6
35.9
g/l
0.67
88
650
75
502
1.77
3.65
3.1
3.1
—
—
—
0
0
84
608
1.64
2.95
2.9
3.7
17.8
35.0
ng/l
1.56
50
392
47
291
1.79
2.91
1.9
1.6
942.2
1207.1
nmol/l
1.12
37
219
63
428
1.68
2.81
2.0
2.2
3.3
3.0
mg/l
0.38
52
375
34
196
1.88
2.63
1.5
1.7
—
—
—
0
0
141
1184
1.59
2.50
4.8
4.2
—
—
—
0
0
81
613
1.53
2.23
4.1
3.7
40.2
64.0
e6/l
0.62
65
426
110
888
1.51
2.23
5.7
7.0
10.4
12.3
umol/l
1.15
101
842
67
491
1.54
2.12
2.9
4.2
7.4
7.4
ph
—
8
80
75
566
1.51
2.07
3.8
3.5
2.4
2.4
mmol/l
0.13
61
491
42
603
0.62
2.04
2.1
2.7
—
—
—
0
0
59
429
1.52
1.92
2.8
3.7
—
—
—
0
0
25
145
1.82
1.92
3.7
4.0
—
—
—
0
0
43
293
1.59
1.85
2.9
2.8
2.4
2.4
mmol/l
2.03
36
251
13
60
2.24
1.82
13.0
4.4
—
—
—
0
0
58
427
1.50
1.77
3.2
4.3
—
—
—
0
0
63
482
1.44
1.57
3.6
2.9
—
—
—
0
0
5
126
0.38
1.56
1.2
1.4
—
—
—
0
0
10
202
0.47
1.56
1.8
1.3
—
—
—
0
0
64
493
1.43
1.53
3.6
3.0
0.2
0.3
e6/l
0.54
52
362
68
531
1.42
1.51
3.5
3.1
26.0
162.1
e6/l
0.57
59
403
7
152
0.44
1.50
3.1
3.5
—
—
—
0
0
21
126
1.74
1.46
2.8
3.4
—
—
—
0
0
14
74
1.96
1.43
1.6
1.6
263.4
341.9
mu/l
0.64
14
67
39
277
1.50
1.40
1.9
5.5
0.8
0.8
mmol/l
0.08
34
262
27
176
1.61
1.40
1.4
4.4
2.0
1.7
%
0.64
20
163
65
516
1.38
1.29
2.0
2.6
52.3
54.0
u/l
0.22
60
483
9
44
2.09
1.28
2.2
3.5
—
—
—
0
0
17
100
1.76
1.28
9.8
8.9
—
—
—
0
0
77
631
1.35
1.25
2.3
1.9
98.5
97.0
pmol/l
0.09
47
306
147
1329
1.36
1.21
4.3
3.9
14.6
14.7
pmol/l
0.12
134
1198
94
797
1.33
1.21
2.5
2.8
129.8
97.8
ug/l
0.57
86
737
7
33
2.16
1.06
1.0
1.2
—
—
—
0
0
9
49
1.87
1.00
12.9
3.9
3.7
3.8
mmol/l
—
9
43
9
50
1.84
0.98
2.4
2.7
—
—
—
0
0
184
1749
1.45
0.93
16.7
13.6
21.5
21.7
mg/l
0.04
162
1373
5
102
0.48
0.92
3.4
1.8
—
—
—
0
0
5
102
0.48
0.92
3.4
1.8
—
—
—
0
0
5
103
0.47
0.92
3.4
1.8
—
—
—
0
0
5
104
0.47
0.91
1.6
1.8
—
—
—
0
0
157
1668
0.76
0.89
4.8
4.6
2.8
2.8
mmol/l
0.49
145
1539
32
240
1.39
0.89
2.2
2.1
—
—
—
0
0
6
30
2.03
0.87
2.3
1.6
—
—
—
0
0
70
594
1.27
0.84
4.4
6.9
—
—
—
0
0
155
1643
0.78
0.80
4.2
4.2
4.7
4.7
mmol/l
0.57
142
1530
5
98
0.50
0.80
3.2
1.8
—
—
—
0
0
33
255
1.35
0.78
2.8
2.9
1.0
0.8
ug/l
0.82
21
163
0
27
0.00
0.78
0.0
1.3
—
—
—
0
0
168
1587
1.30
0.77
5.3
4.6
1.7
2.6
mu/l
0.66
155
1446
8
133
0.59
0.76
1.3
3.6
64.8
66.6
g/l
—
8
125
41
329
1.31
0.76
1.7
1.7
447.2
483.1
pmol/l
0.37
33
284
154
1630
0.79
0.75
4.2
4.2
1.5
1.5
mmol/l
0.04
142
1507
31
392
0.75
0.72
1.8
2.1
0.7
1.2
mg/l
1.93
25
308
42
341
1.29
0.71
2.3
2.7
503.0
555.3
mosm/kgh2o
0.86
36
290
24
179
1.39
0.71
3.6
6.6
—
—
—
0
0
18
127
1.46
0.70
1.6
4.0
64.8
73.5
e9/l
0.45
12
99
141
1311
1.23
0.70
7.1
7.4
77.2
81.4
u/l
0.67
133
1218
5
28
1.80
0.66
1.4
1.9
—
—
—
0
0
46
383
1.26
0.65
3.6
3.9
1.0
1.0
kg/l
0.04
11
49
28
218
1.33
0.64
1.3
1.2
—
—
—
0
0
15
105
1.46
0.62
1.2
1.2
—
—
—
0
0
5
30
1.68
0.62
1.0
10.9
—
—
—
0
0
188
1817
1.36
0.61
14.4
11.9
—
—
—
0
0
10
150
0.65
0.60
2.7
4.4
2.2
1.0
%
—
5
45
34
413
0.79
0.58
4.2
4.6
—
—
—
0
0
9
61
1.50
0.54
1.0
1.1
—
—
—
0
0
100
920
1.17
0.49
4.9
6.6
0.6
0.6
e9/l
0.11
84
802
103
950
1.17
0.49
4.9
6.6
1.8
1.9
e9/l
0.47
88
855
168
1618
1.20
0.44
17.2
15.0
40.0
40.0
%
0.03
124
1257
36
418
0.83
0.42
1.9
2.9
316.9
8038.0
umol/l
2.24
30
358
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
3.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
14.1
—
1362.6
—
0
16
99
920
1.15
0.41
4.9
6.6
0.0
0.0
e9/l
0.33
83
803
0
18
0.00
0.40
0.0
1.3
—
5.5
—
0
7
0
19
0.00
0.39
0.0
3.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
3.4
—
0
10
34
292
1.20
0.38
3.6
3.7
43.6
133.6
ng/l
1.23
23
224
27
318
0.83
0.36
1.5
1.6
—
—
—
0
0
12
90
1.35
0.36
3.7
2.3
—
—
—
0
0
5
76
0.65
0.36
4.4
2.3
—
—
—
0
0
9
123
0.72
0.36
1.1
1.4
—
—
—
0
0
5
78
0.63
0.36
1.0
3.9
20.4
22.8
s
—
5
71
97
907
1.13
0.35
4.7
6.8
27.5
29.3
%
0.74
92
854
120
1137
1.13
0.35
3.7
3.7
—
—
—
0
0
45
503
0.87
0.34
2.6
3.3
7.9
7.6
mmol/l
0.12
38
421
100
941
1.12
0.32
4.9
7.1
0.2
0.2
e9/l
0.27
86
842
55
500
1.14
0.31
1.5
1.5
—
—
—
0
0
14
111
1.28
0.31
4.4
5.0
—
—
—
0
0
23
195
1.20
0.30
1.2
1.2
—
—
—
0
0
8
107
0.74
0.30
1.4
2.9
—
—
—
0
0
20
237
0.83
0.29
1.9
1.5
—
—
—
0
0
11
139
0.78
0.28
3.8
2.5
8.8
10.0
g/l
0.85
11
129
8
65
1.24
0.27
2.1
1.8
—
—
—
0
0
43
389
1.13
0.26
4.1
3.7
—
—
—
0
0
89
846
1.09
0.22
3.8
3.6
0.0
0.0
estimate
0.00
11
172
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
156.4
—
0
10
14
166
0.83
0.21
1.1
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
37
405
0.89
0.21
1.2
1.4
2.3
2.1
g/l
0.22
22
245
0
13
0.00
0.21
0.0
1.2
—
52733.3
—
0
6
0
13
0.00
0.21
0.0
1.4
—
1.0
—
0
13
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.7
—
32.8
—
0
13
41
445
0.90
0.20
3.1
4.0
2.0
8.6
mg/mmol
3.63
25
278
14
164
0.84
0.19
1.9
1.8
—
—
—
0
0
21
185
1.15
0.19
1.3
1.3
—
—
—
0
0
18
157
1.16
0.18
1.1
1.2
—
—
—
0
0
19
215
0.87
0.17
1.2
1.5
—
—
—
0
0
154
1573
0.92
0.17
3.7
3.8
1.3
1.3
mmol/l
0.11
141
1450
6
77
0.77
0.16
1.2
1.1
—
—
—
0
0
131
1276
1.07
0.16
3.9
4.0
11.4
10.8
mm/h
0.17
120
1166
7
85
0.82
0.15
3.1
3.5
—
—
—
0
0
7
88
0.79
0.15
1.3
1.8
—
—
—
0
0
47
497
0.93
0.13
3.2
3.1
—
—
—
0
0
49
465
1.07
0.12
5.6
8.5
—
—
—
0
0
16
143
1.13
0.12
1.3
1.5
—
—
—
0
0
16
143
1.13
0.12
4.1
4.4
—
7.4
—
0
12
11
125
0.87
0.10
3.5
2.5
—
15.4
—
0
6
183
1847
0.92
0.09
10.0
10.1
25.8
25.7
u/l
0.04
176
1785
109
1067
1.05
0.09
7.2
10.3
4.2
4.0
e9/l
0.44
93
937
6
58
1.04
0.08
1.0
1.3
—
—
—
0
0
6
58
1.04
0.08
1.0
1.2
—
—
—
0
0
150
1520
0.95
0.08
5.5
5.3
37.3
39.3
mmol/mol
2.53
140
1427
5
61
0.82
0.08
1.6
1.7
—
—
—
0
0
7
65
1.08
0.08
8.3
9.5
1.1
1.4
mg/l
—
7
60
80
820
0.96
0.07
6.3
10.3
0.0
0.0
e9/l
0.53
60
656
7
82
0.85
0.07
5.3
4.9
10.2
8.9
kpa
—
7
73
25
237
1.06
0.06
1.4
1.6
—
—
—
0
0
87
853
1.03
0.06
5.7
4.9
0.0
0.0
estimate
0.00
11
173
30
287
1.05
0.05
1.3
1.3
11.5
30.9
iu/ml
—
10
102
41
424
0.96
0.05
2.4
3.2
21.3
360.6
mg/l
0.94
24
268
46
471
0.97
0.03
3.8
3.9
0.0
0.0
estimate
—
10
168
23
221
1.05
0.03
1.2
1.4
208.0
494.0
titre
—
5
60
152
1512
1.02
0.01
22.5
17.9
333.2
332.6
g/l
0.39
152
1505
22
213
1.04
0.01
1.4
1.8
—
—
—
0
0
38
373
1.02
0.01
1.8
2.0
—
—
—
0
0
195
1949
1.01
0.00
24.3
19.9
6.9
6.6
e9/l
1.24
189
1894
195
1949
1.01
0.00
24.3
19.9
4.5
4.5
e12/l
0.03
189
1895
86
864
0.99
0.00
4.2
3.7
0.0
0.0
estimate
0.00
11
168
11
113
0.97
0.00
1.8
1.3
—
24.9
—
0
8
13
127
1.03
0.00
3.9
2.6
—
—
—
0
0
162
1617
1.01
0.00
4.4
4.2
5.6
5.9
mmol/l
2.30
150
1477
44
438
1.01
0.00
1.2
1.3
5.6
1.2
u/ml
0.48
12
118
195
1948
1.02
0.00
24.3
19.9
261.3
252.1
e9/l
1.26
189
1898
28
278
1.01
0.00
1.4
1.3
9.4
8.3
u/ml
0.05
13
116
0
8
0.00
0.00
0.0
2.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
33.2
—
0.6
—
0
5
6
60
1.00
0.00
10.5
8.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
6
67
0.89
0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
9.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
4.8
—
1.3
—
0
9
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
7
73
0.96
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
11.8
—
1.1
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
8.2
—
24.7
—
0
6
0
5
0.00
0.00
0.0
4.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
136.3
—
0
6
0
6
0.00
0.00
0.0
1.2
—
70.0
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
9
96
0.93
0.00
1.7
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
1.2
—
0
6
0
5
0.00
0.00
0.0
1.2
—
4.3
—
0
5
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
5.4
—
49.7
—
0
7

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_BRAIN_INFRATENT and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_BRAIN_INFRATENT 1.861 [1.47, 2.35] < 0.001
Birth year 0.994 [0.99, 1.0] 0.201

During the follow-up period (1.1.1998 — 31.12.2019), 125 out of 692 females with CD2_BENIGN_BRAIN_INFRATENT died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_BRAIN_INFRATENT 2.417 [1.8, 3.24] < 0.001
Birth year 0.992 [0.98, 1.0] 0.089

During the follow-up period (1.1.1998 — 31.12.2019), 122 out of 603 males with CD2_BENIGN_BRAIN_INFRATENT died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_BRAIN_INFRATENT.

N-year risk Females Males
1 0.215% 0.496%
5 1.161% 3.052%
10 2.919% 7.476%
15 5.319% 14.591%
20 9.131% 24.239%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_BRAIN_INFRATENT – Benign neoplasm: Brain, infratentorial

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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