cranial nerve malignant neoplasm: Benign and malignant neoplasms that arise from one or more of the twelve cranial nerves.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1011 |
4. Check minimum number of eventsNone |
1011 |
5. Include endpointsNone |
1011 |
6. Filter based on genotype QC (FinnGen only) |
1011 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D33
- Name in latin
- Neoplasma benignum nervi cranialis
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Cranial nerves
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Cranial nerves
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6100 | 3369 | 2687 |
| Only index persons | 5447 | 3043 | 2404 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.10 | 0.08 |
| Only index persons | 0.10 | 0.11 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 56.38 | 56.92 | 55.69 |
| Only index persons | 55.98 | 56.46 | 55.36 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1011 | 570 | 441 |
| Unadjusted period prevalence (%) | 0.19 | 0.19 | 0.19 |
| Median age at first event (years) | 56.65 | 55.49 | 58.16 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 896
- Matched controls
- 8959
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D33.30
ICD-10 Finland
Acoustic neuroma
4503599627370496.0
323.0
744
*
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
99.1
251.8
271
39
9560/0-C72.4
ICD-O-3
Schwannoma, NOS, of acoustic nerve
+∞
236.2
216
*
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
63.2
164.2
190
38
DFF00
NOMESCO Finland
Pure tone audiometry
10.2
135.0
298
418
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
16.7
131.2
220
171
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
9.6
111.1
249
345
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
47.2
100.8
123
30
D33.3
ICD-10 Finland
Benign neoplasm: Cranial nerves
+∞
85.8
81
*
D33.39
ICD-10 Finland
Benign tumor of the cranial nerves UNS
+∞
84.7
80
*
2251A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Cranial nerves
+∞
82.6
78
*
D33.37
ICD-10 Finland
Another benign tumor of the cranial nerves
+∞
82.6
78
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
5.2
77.7
284
733
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
4.6
73.6
308
909
DFF15
NOMESCO Finland
Speech audiometry
9.5
67.5
146
179
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
36.4
66.9
86
26
DFF59
NOMESCO Finland
Other assessment of balance
26.6
56.1
78
32
G51.0
ICD-10 Finland
Bell palsy
11.0
49.8
98
99
22510
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Cranial nerves (including optic)
+∞
49.4
47
*
AAE32
NOMESCO Finland
Translabyrinthine excision acoustic neurinome
+∞
47.3
45
*
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
96.9
42.2
46
5
AAE34
NOMESCO Finland
Other operations on acoustical nerv
+∞
38.8
37
*
H02.2
ICD-10 Finland
Lagophthalmos
51.3
36.9
44
9
N07CA01
ATC
betahistine; oral
4.3
36.2
148
397
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
8.8
34.6
76
93
9560/0-C72.5
ICD-O-3
Schwannoma, NOS, of cranial nerve, NOS
+∞
34.6
33
*
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
96.4
34.0
37
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
9.1
33.0
71
84
UDC00
NOMESCO Finland
Ear microscopy
4.1
27.8
114
304
H93.1
ICD-10 Finland
Tinnitus
4.1
27.5
113
302
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
11.7
26.9
50
45
Q85.01
ICD-10 Finland
Neurofibromatosis, type 2
139.0
25.7
27
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.7
25.4
120
361
2152
FHL
Extraction, big brain
40.1
25.0
31
8
DE2CM
NOMESCO Finland
Acoustic channel extensive MRI examination with 3 Tesla magnet
57.7
24.1
28
5
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
21.8
193
878
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
15.3
20.8
34
23
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
3.6
20.8
99
299
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
214.7
20.7
21
*
WF099
NOMESCO Finland
Other radiotherapy
16.5
20.2
32
20
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
6.2
19.8
54
92
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
25.2
19.6
27
11
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
71.4
18.8
21
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
18.8
406
2706
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
12.6
18.7
33
27
R5120
NOMESCO Finland
Preparation of an aid
5.6
18.3
54
102
AA1AD
NOMESCO Finland
CT of head and brain
2.1
18.0
257
1452
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
7.3
18.0
43
61
R42
ICD-10 Finland
Dizziness and giddiness
2.1
17.3
237
1312
ZZC00
NOMESCO Finland
Graft of fascia
64.6
16.8
19
*
9560/0-C72.9
ICD-O-3
Schwannoma, NOS, of nervous system, NOS
+∞
16.7
16
*
ZXC40
NOMESCO Finland
Use of ultrasound
11.9
16.6
30
26
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
8.9
14.8
31
36
ZX050
NOMESCO Finland
Stereotactic radiotherapy
13.5
14.8
25
19
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
36.7
14.5
18
5
8000/0-C72.4
ICD-O-3
Neoplasm, benign of acoustic nerve
+∞
13.6
13
*
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
3.4
13.5
65
199
DE2DG
NOMESCO Finland
Acoustic channel very extensive MRI examination with high intensity magnet
142.0
13.5
14
*
CBH30
NOMESCO Finland
Tarsorraphy
142.0
13.5
14
*
H91.9
ICD-10 Finland
Hearing loss, unspecified
3.5
12.9
60
179
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
14.3
12.8
21
15
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
12.8
267
1698
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
4.5
12.7
45
105
DAX08
NOMESCO Finland
Fitting of hearing aid
3.5
12.6
60
182
G91.1
ICD-10 Finland
Obstructive hydrocephalus
18.3
12.1
18
10
3252
FHL
Repair with foreign material (spring, magnet)
+∞
11.5
11
*
D33.03
ICD-10 Finland
Pilosytic lateral astrocytoma of the strobe brain
+∞
11.5
11
*
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
35.5
11.3
14
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
11.2
122
603
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
6.5
11.1
28
44
H02
ICPC
Hearing complaint
2.2
11.0
123
616
DE2BM
NOMESCO Finland
Acoustic channel MRI examination with 3 Tesla magnet
43.9
10.9
13
*
Q85.09
ICD-10 Finland
Unspecified neurofibromatosis
43.9
10.9
13
*
CBH25
NOMESCO Finland
Tarsorrhaphy
28.4
10.7
14
5
Q85.1
ICD-10 Finland
Tuberous sclerosis
111.2
10.4
11
*
AAH50
NOMESCO Finland
Cranial nerve anastomosis
111.2
10.4
11
*
H47.1
ICD-10 Finland
Papilloedema, unspecified
19.0
10.3
15
8
ZXH01
NOMESCO Finland
Procedure performed within operation theatre
11.5
10.1
18
16
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
40.5
10.0
12
*
Z97.4
ICD-10 Finland
Presence of external hearing-aid
3.0
9.8
56
194
QAJ10
NOMESCO Finland
Browlift
10.8
9.8
18
17
G50.0
ICD-10 Finland
Trigeminal neuralgia
5.6
9.7
27
49
XX3DW
NOMESCO Finland
Time consuming IT work
2.1
9.7
109
546
WF002
NOMESCO Finland
Radical radiotherapy
2.8
9.6
61
228
CBW99
NOMESCO Finland
Other operation on eyelid
101.0
9.4
10
*
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
+∞
9.4
9
*
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
9.4
103
512
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
13.8
9.2
15
11
R4110
NOMESCO Finland
Physiotherapy
1.7
9.1
246
1667
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
10.2
9.0
17
17
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
8.8
211
1379
D33.7
ICD-10 Finland
Benign neoplasm: Other specified parts of central nervous system
50.5
8.7
10
*
WX110
NOMESCO Finland
Local anesthesy
1.5
8.6
573
4801
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
11.7
8.6
15
13
N03AF01
ATC
carbamazepine; oral, rectal
2.7
8.5
58
227
D32.05
ICD-10 Finland
Cerebral meninges
27.8
8.5
11
*
ZZK00
NOMESCO Finland
Graft of nerve
90.9
8.4
9
*
H81.3
ICD-10 Finland
Other peripheral vertigo
3.5
8.2
36
105
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
3.6
8.0
34
96
D32.04
ICD-10 Finland
Secondary or multiple benign tumor of the meninges above the exam
22.2
8.0
11
5
D32.01
ICD-10 Finland
Benign tumor of meninges on interhemispheric surface
10.9
7.8
14
13
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
45.4
7.7
9
*
H02.1
ICD-10 Finland
Ectropion of eyelid
6.8
7.6
18
27
9530/0-C70.9
ICD-O-3
Meningioma, NOS, of meninges, NOS
18.5
7.6
11
6
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
5.2
7.6
22
43
D33.2
ICD-10 Finland
Benign neoplasm: Brain, unspecified
25.2
7.6
10
*
H81.0
ICD-10 Finland
Ménière disease
3.6
7.4
32
92
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
5.3
7.4
21
40
DC1AD
NOMESCO Finland
Temporalbone CT
6.0
7.4
19
32
N03AF02
ATC
oxcarbazepine; oral
3.2
7.4
36
114
3259
FHL
Other measure in this category
+∞
7.3
7
*
2159
FHL
Other measure in this category
+∞
7.3
7
*
TAB00
NOMESCO Finland
Lumbar puncture
2.8
7.3
46
171
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
5.9
7.2
19
33
SPAT1043
SPAT
Audiometry
1.9
7.1
102
564
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
10.1
7.0
13
13
R51.80
ICD-10 Finland
Headache
1.8
7.0
119
697
Z31.5
ICD-10 Finland
Genetic counselling
2.6
6.9
48
189
D36.1
ICD-10 Finland
Benign neoplasm: Peripheral nerves and autonomic nervous system
13.9
6.9
11
8
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.3
6.8
32
99
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.7
6.8
28
78
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
11.0
6.8
12
11
Q85.0
ICD-10 Finland
Neurofibromatosis (nonmalignant)
40.4
6.8
8
*
CBK10
NOMESCO Finland
Operation for lagophtalmus
40.4
6.8
8
*
AAK40
NOMESCO Finland
Closure of cerebrospinal fluid fistula
40.4
6.8
8
*
R4135
NOMESCO Finland
Rehabilitation for hearing problems
4.3
6.6
23
55
WX402
NOMESCO Finland
General anaesthesia
1.7
6.6
139
871
ZXA05
NOMESCO Finland
Left side
1.5
6.5
230
1646
XCK00
NOMESCO Finland
Perimetry
2.1
6.4
67
326
TQA05
NOMESCO Finland
Puncture of skin of head or neck
70.3
6.4
7
*
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.5
6.4
49
206
QAJ30
NOMESCO Finland
Other facelift
14.4
6.4
10
7
D33.45
ICD-10 Finland
Benign Schwannom in the nerve root of the spinal cord
14.4
6.4
10
7
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
6.3
176
1190
RK520
NOMESCO Finland
NA
9.3
6.3
12
13
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
6.3
136
859
D43.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Cranial nerves
+∞
6.3
6
*
D33
ICD-10 Finland
Benign neoplasm of brain and other parts of central nervous system
+∞
6.3
6
*
9560/0-C71.9
ICD-O-3
Schwannoma, NOS, of brain, NOS
+∞
6.3
6
*
3253
FHL
Tarsoraphy
+∞
6.3
6
*
N76
ICPC
Neoplasm nervous system unspecified
26.9
6.2
8
*
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
7.7
6.1
13
17
ZZF00
NOMESCO Finland
Graft of adipose tissue
6.8
6.0
14
21
G50.1
ICD-10 Finland
Atypical facial pain
3.8
6.0
23
61
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
58
50
12.25
57.16
1.8
1.9
—
—
—
0
0
528
3984
1.68
14.49
6.3
5.9
1.2
1.2
mmol/l
0.37
488
3598
553
4342
1.60
12.04
7.0
6.7
1.2
1.2
mmol/l
0.56
485
3669
618
5062
1.57
10.60
5.1
4.8
6.6
6.7
mmol/l
1.37
596
4752
300
2084
1.62
10.54
1.9
2.3
—
—
—
0
0
167
1002
1.80
10.03
7.2
7.5
0.8
1.2
mmol/l
0.51
120
790
166
1005
1.78
9.65
7.2
7.5
15.9
12.1
kpa
10.31
156
968
166
1005
1.78
9.65
7.2
7.5
5.1
5.1
kpa
0.02
157
968
110
584
1.99
9.61
2.4
2.5
28.4
18.1
au/ml
—
8
24
101
529
2.01
9.16
1.3
1.3
19.0
53.7
au/ml
—
5
27
50
198
2.60
8.76
1.7
1.2
83.2
30.4
e6/l
0.35
39
152
50
198
2.60
8.76
1.9
1.3
2161.9
695.5
e6/l
0.34
42
158
936
8728
1.98
7.59
18.3
17.2
139.9
139.7
mmol/l
1.62
920
8504
494
4027
1.44
7.52
3.6
4.0
—
—
—
0
0
904
8366
1.76
7.13
15.1
14.8
24.9
24.3
mg/l
0.16
735
6687
935
8751
1.91
6.96
18.5
17.4
3.9
4.0
mmol/l
2.51
918
8519
17
42
4.10
6.37
2.2
1.2
—
—
—
0
0
859
7979
1.51
5.16
15.0
13.8
79.7
79.1
ml/min/173m2
0.41
727
6576
422
3512
1.35
4.98
2.4
2.2
78.9
77.7
nmol/l
0.45
373
3121
938
8954
1.66
4.24
11.1
10.8
25.8
25.9
u/l
0.04
911
8637
827
7704
1.40
4.16
4.9
4.7
1.9
2.1
mu/l
0.83
748
6990
520
4538
1.30
4.11
5.8
6.3
12.2
11.6
umol/l
0.35
499
4312
696
6323
1.32
4.06
4.0
4.2
11.4
12.6
mm/h
1.23
637
5820
725
6639
1.33
3.91
7.6
7.6
78.1
78.8
u/l
0.15
684
6213
436
3755
1.28
3.68
4.2
4.6
35.8
35.3
g/l
0.96
403
3496
84
550
1.58
3.63
10.1
9.2
0.7
0.7
%
0.16
84
544
320
2661
1.30
3.52
2.3
2.1
179.2
235.0
u/l
0.89
306
2506
961
9280
1.72
3.51
23.1
22.0
134.7
134.8
g/l
0.06
954
9136
84
557
1.55
3.45
10.1
9.0
1.1
1.3
%
2.13
84
551
83
551
1.55
3.39
10.2
9.3
94.8
93.9
%
0.41
83
545
548
4886
1.27
3.38
8.5
9.2
4.2
4.1
e9/l
0.20
461
4286
14
49
2.88
3.20
1.7
1.3
19.1
19.1
nmol/l
0.00
14
43
206
1632
1.33
3.19
3.4
3.0
0.7
0.8
ug/l
0.35
139
1079
542
4866
1.25
3.00
2.7
2.7
—
—
—
0
0
150
1155
1.35
2.81
4.6
5.4
1.0
1.0
mmol/l
0.63
140
1061
32
173
1.88
2.79
1.6
1.3
13.3
10.5
u/l
0.30
20
141
107
780
1.42
2.79
4.4
6.9
9.1
9.6
mmol/l
0.33
101
745
202
1634
1.30
2.67
3.0
3.0
2.5
2.5
mmol/l
0.15
171
1435
410
3608
1.23
2.62
2.1
2.0
95.2
95.2
pmol/l
0.00
220
1831
21
100
2.12
2.60
1.4
1.4
249.6
321.1
pmol/l
0.85
16
79
177
1427
1.29
2.40
3.2
3.3
0.8
0.8
mmol/l
1.46
166
1334
5
8
6.27
2.37
2.6
2.8
58.4
91.5
pmol/l
—
5
8
340
2970
1.22
2.27
3.4
3.4
2.4
2.4
mmol/l
0.35
280
2574
686
6420
1.21
2.18
4.1
3.9
14.9
14.9
pmol/l
0.03
618
5807
592
5466
1.20
2.16
3.2
3.2
47.4
50.4
u/l
0.38
554
5077
16
76
2.12
2.03
1.0
1.0
—
—
—
0
0
9
32
2.83
2.00
3.1
3.1
27.7
33.1
umol/l
—
9
24
319
2803
1.20
1.96
5.7
5.0
3.4
2.8
ug/l
0.28
284
2501
53
364
1.48
1.95
2.5
2.0
36.6
39.8
u/l
0.49
46
322
262
2261
1.21
1.94
4.8
4.3
22.6
21.4
%
0.62
139
1082
14
67
2.10
1.76
1.1
1.3
—
—
—
0
0
307
2712
1.19
1.76
3.4
3.3
36.3
32.7
u/l
0.36
291
2583
17
88
1.95
1.75
1.0
1.1
—
—
—
0
0
599
5593
1.17
1.74
4.8
4.6
711.2
2176.2
e6/l
—
10
88
165
1378
1.24
1.68
2.9
3.0
2.4
2.3
e6/l
0.04
86
756
860
8302
1.24
1.67
4.6
4.5
1.5
1.5
mmol/l
0.33
779
7590
176
1482
1.23
1.66
2.8
2.8
1.3
1.2
e6/l
0.12
94
857
73
549
1.36
1.66
1.5
1.6
—
—
—
0
0
865
8359
1.24
1.64
4.6
4.6
4.7
4.6
mmol/l
0.69
792
7696
5
134
0.37
1.61
1.4
1.6
—
—
—
0
0
5
14
3.58
1.61
2.0
5.9
—
—
—
0
0
272
2398
1.18
1.58
3.3
3.2
0.4
0.5
e6/l
0.20
201
1827
76
583
1.33
1.53
2.3
2.2
11.9
13.1
nmol/l
0.54
65
513
116
948
1.25
1.45
4.3
4.0
242.0
252.2
u/l
0.25
105
894
50
366
1.39
1.37
1.3
1.8
—
—
—
0
0
6
23
2.62
1.37
1.5
1.3
—
—
—
0
0
36
250
1.46
1.32
1.5
1.6
—
—
—
0
0
783
7539
1.17
1.31
17.7
15.9
40.1
39.6
%
0.91
573
5207
721
6900
1.16
1.31
19.2
18.1
13.7
13.7
%
0.40
711
6754
20
318
0.62
1.31
2.8
2.8
—
—
—
0
0
15
256
0.58
1.30
1.3
1.7
—
—
—
0
0
46
339
1.37
1.24
1.3
1.7
—
—
—
0
0
876
8528
1.20
1.22
5.2
5.1
2.8
2.7
mmol/l
0.88
796
7801
239
2128
1.16
1.22
1.5
1.5
21.4
20.9
nmol/l
0.20
190
1783
16
93
1.73
1.21
1.0
1.1
—
—
—
0
0
827
8015
1.17
1.20
4.1
4.1
1.3
1.3
mmol/l
0.59
735
7279
14
82
1.72
1.05
1.0
1.1
—
—
—
0
0
9
48
1.88
1.00
1.8
6.4
—
48.1
—
0
12
7
35
2.01
1.00
1.3
1.9
1.0
6.9
nmol/l
—
7
27
5
23
2.18
0.98
1.2
1.1
—
—
—
0
0
5
23
2.18
0.98
1.2
1.1
—
—
—
0
0
33
243
1.37
0.93
1.5
1.4
—
—
—
0
0
94
793
1.20
0.93
2.7
2.5
32.4
41.4
u/l
0.60
82
676
128
1113
1.17
0.91
5.0
4.6
32.3
32.5
%
0.07
77
727
83
696
1.21
0.88
2.7
2.8
60.6
64.7
ml/min/173m2
0.46
34
288
28
205
1.38
0.84
2.0
1.4
299.5
284.3
mu/l
0.14
28
187
37
285
1.31
0.81
4.3
3.7
36.1
47.3
mg/l
0.27
29
235
37
285
1.31
0.81
4.2
3.7
51.5
73.1
mg/l
0.40
29
233
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
8
47
1.71
0.80
1.0
1.1
—
—
—
0
0
10
58
1.73
0.80
1.1
1.0
—
—
—
0
0
0
25
0.00
0.79
0.0
1.5
—
—
—
0
0
18
123
1.47
0.78
1.3
1.2
1.8
2.4
u/ml
—
8
33
69
577
1.21
0.77
3.5
3.8
5.0
5.1
kpa
1.72
60
543
805
7856
1.12
0.76
6.0
6.0
39.3
40.1
mmol/mol
1.71
728
7236
0
28
0.00
0.76
0.0
1.1
—
330.8
—
0
16
9
53
1.70
0.75
1.0
1.2
—
—
—
0
0
25
184
1.37
0.74
2.1
2.2
130.5
128.5
g/l
0.13
17
137
294
2741
1.10
0.72
2.5
2.4
62.9
57.7
u/l
0.42
271
2535
56
464
1.22
0.70
2.5
3.3
4.6
4.5
pmol/l
0.13
51
402
199
1824
1.11
0.67
2.7
2.6
5.0
5.7
e6/l
0.40
171
1614
845
8285
1.12
0.67
4.9
4.7
5.8
6.0
mmol/l
3.16
752
7514
160
1452
1.12
0.65
1.6
1.9
—
—
—
0
0
11
164
0.67
0.62
1.5
1.6
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
0.6
—
0
14
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
2.2
—
—
—
0
0
141
1279
1.12
0.59
2.1
2.3
2.3
2.3
g/l
0.06
125
1187
10
64
1.57
0.58
1.1
1.1
—
—
—
0
0
10
64
1.57
0.58
1.1
1.1
—
—
—
0
0
234
2180
1.10
0.58
2.2
2.1
3.0
3.1
mg/l
0.24
198
1847
171
1860
0.90
0.58
1.7
1.6
1.3
1.2
mg/l
0.05
123
1425
207
2227
0.91
0.57
4.5
4.2
0.0
0.0
estimate
0.50
76
764
6
36
1.67
0.56
1.0
1.0
—
—
—
0
0
6
36
1.67
0.56
1.0
1.3
—
—
—
0
0
132
1196
1.12
0.56
2.2
2.4
23.9
22.3
%
0.40
110
1030
44
366
1.21
0.56
3.7
4.2
24.4
24.9
mmol/l
0.81
39
348
17
124
1.38
0.56
1.4
1.2
1.6
5.6
u/ml
—
9
53
10
65
1.54
0.55
1.1
1.1
—
—
—
0
0
10
65
1.54
0.55
1.1
1.1
—
—
—
0
0
10
65
1.54
0.55
1.1
1.1
—
—
—
0
0
9
60
1.50
0.54
1.2
1.2
—
—
—
0
0
63
547
1.16
0.51
3.6
3.8
0.8
1.8
mmol/l
2.85
49
419
433
4160
1.07
0.50
3.8
3.9
0.0
0.0
estimate
0.50
77
758
428
4111
1.07
0.50
5.2
5.2
0.0
0.0
estimate
0.00
76
789
7
45
1.56
0.49
1.0
1.1
—
—
—
0
0
22
278
0.79
0.48
1.7
1.9
—
—
—
0
0
104
940
1.12
0.48
3.9
4.2
15.0
24.8
ug/l
0.35
84
784
11
76
1.45
0.48
1.1
1.4
—
—
—
0
0
7
48
1.46
0.47
1.0
1.1
—
—
—
0
0
16
120
1.34
0.46
1.3
1.1
—
—
—
0
0
13
176
0.74
0.46
1.3
1.5
—
—
—
0
0
7
49
1.43
0.46
1.4
1.6
—
—
—
0
0
7
49
1.43
0.46
1.4
1.6
—
—
—
0
0
14
187
0.75
0.46
3.1
3.6
13.7
28.1
mg/l
—
7
114
22
174
1.27
0.45
1.4
1.2
—
7.7
—
0
14
10
141
0.71
0.45
1.7
1.5
—
—
—
0
0
9
127
0.71
0.43
1.7
1.5
—
—
—
0
0
353
3387
1.06
0.42
3.5
3.7
40.1
50.9
ng/l
0.22
247
2450
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
178
1668
1.08
0.41
1.7
1.7
1098.3
1194.4
nmol/l
0.74
132
1246
120
1105
1.10
0.41
7.0
7.3
—
—
—
0
0
33
390
0.84
0.41
1.0
1.0
—
—
—
0
0
31
260
1.20
0.39
1.7
1.6
0.0
0.1
iu/ml
—
5
45
30
251
1.20
0.39
1.1
1.4
—
—
—
0
0
251
2637
0.94
0.39
2.7
3.0
1396.4
1284.9
ng/l
0.14
218
2254
10
71
1.41
0.39
1.7
1.8
—
—
—
0
0
177
1662
1.08
0.39
3.7
3.9
122.7
318.1
ng/l
1.98
145
1312
0
19
0.00
0.39
0.0
1.0
—
26.0
—
0
19
29
243
1.20
0.38
1.6
1.7
—
—
—
0
0
10
136
0.73
0.38
1.0
1.1
—
12.5
—
0
10
27
225
1.21
0.37
1.5
1.7
11157.3
13721.3
e6/l
0.16
22
164
14
107
1.31
0.37
1.1
1.0
2.7
2.3
u/ml
—
6
44
35
300
1.17
0.36
4.4
2.7
1.0
1.2
g/l
0.15
26
262
5
78
0.64
0.35
1.2
1.2
—
—
—
0
0
13
99
1.32
0.35
1.1
1.3
6.2
7.2
mmol/l
—
8
64
19
233
0.81
0.35
1.2
1.2
—
—
—
0
0
25
209
1.20
0.34
1.4
1.3
—
—
—
0
0
71
781
0.90
0.34
2.7
2.4
6.2
7.0
ug/l
0.30
60
691
148
1390
1.08
0.33
2.1
2.3
12.8
12.8
umol/l
0.00
132
1286
86
789
1.10
0.33
2.9
2.1
361.2
376.4
nmol/l
0.26
78
727
423
4106
1.05
0.33
3.8
3.8
0.0
0.0
estimate
0.00
71
778
6
46
1.31
0.33
3.3
2.3
—
—
—
0
0
75
820
0.91
0.32
3.8
3.4
1.9
2.0
mmol/l
0.10
65
664
10
132
0.76
0.32
1.6
1.6
—
—
—
0
0
13
101
1.29
0.31
1.6
1.9
—
—
—
0
0
27
314
0.86
0.30
1.1
1.2
0.2
1.4
u/ml
—
7
23
7
55
1.27
0.30
1.1
1.1
—
—
—
0
0
10
130
0.77
0.29
1.0
1.1
—
—
—
0
0
27
233
1.16
0.27
1.1
1.2
—
—
—
0
0
124
1168
1.07
0.27
1.2
1.4
—
—
—
0
0
21
178
1.18
0.26
2.4
2.5
15.8
16.0
%
0.05
12
94
133
1404
0.94
0.26
1.3
1.3
33.7
13.6
u/ml
0.32
49
528
20
235
0.85
0.26
3.0
2.4
83.6
87.4
ug/min
0.03
13
140
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
30
263
1.14
0.26
2.7
2.4
0.3
0.4
u/ml
0.10
20
147
365
3553
1.04
0.25
2.8
2.7
126.9
138.0
ug/l
0.24
333
3254
39
433
0.90
0.24
3.3
3.3
25.6
25.4
mmol/l
0.16
39
422
22
254
0.86
0.23
1.3
1.2
—
—
—
0
0
25
218
1.15
0.23
1.8
1.4
—
—
—
0
0
5
38
1.32
0.23
1.2
1.7
—
—
—
0
0
5
38
1.32
0.23
1.2
1.7
—
—
—
0
0
5
39
1.28
0.23
1.2
1.7
—
—
—
0
0
26
228
1.14
0.23
3.2
3.1
22.9
25.1
mmol/l
2.27
19
204
67
721
0.92
0.23
2.9
2.9
126.7
193.8
ng/l
1.34
59
663
119
1129
1.06
0.22
19.0
25.4
1.5
1.3
inr
0.60
12
147
5
41
1.22
0.22
1.0
1.2
—
—
—
0
0
22
191
1.16
0.22
1.2
1.3
119.6
237.0
miu/ml
—
7
90
24
210
1.15
0.22
1.1
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
2.8
—
0.6
—
0
11
0
10
0.00
0.21
0.0
5.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
6
48
1.25
0.20
1.7
1.8
—
—
—
0
0
15
176
0.85
0.20
6.7
3.7
56.3
57.5
%
0.09
15
176
26
291
0.89
0.19
1.4
1.7
1.2
2.9
mg/l
2.35
19
213
18
207
0.87
0.19
1.5
1.5
—
—
—
0
0
51
549
0.93
0.18
4.0
3.0
132.9
127.9
g/l
1.03
51
538
228
2348
0.96
0.18
1.6
1.6
1.3
1.4
mmol/l
0.46
195
1960
40
368
1.09
0.17
1.9
2.0
2.3
2.1
ug/l
0.04
34
327
15
129
1.17
0.17
1.7
1.7
—
—
—
0
0
178
1837
0.96
0.16
3.9
4.2
1.0
1.0
kg/l
0.19
22
260
8
69
1.16
0.16
1.4
1.2
—
—
—
0
0
31
283
1.10
0.16
3.1
2.4
37.8
37.9
g/l
0.04
24
242
8
72
1.11
0.16
1.4
1.1
—
—
—
0
0
11
130
0.84
0.16
2.4
3.2
—
1949.9
—
0
15
17
193
0.88
0.16
1.2
1.3
—
—
—
0
0
6
76
0.79
0.15
1.0
1.5
—
—
—
0
0
102
977
1.05
0.15
2.6
2.8
7.2
8.1
umol/l
0.44
94
849
20
178
1.13
0.15
1.9
1.6
—
—
—
0
0
280
2740
1.03
0.15
2.9
3.1
7.6
7.4
mmol/l
0.25
235
2288
67
635
1.06
0.15
2.1
1.7
—
—
—
0
0
9
83
1.09
0.14
1.8
1.8
—
—
—
0
0
7
87
0.80
0.14
1.1
1.5
—
—
—
0
0
7
87
0.80
0.14
1.1
1.5
—
—
—
0
0
7
87
0.80
0.14
1.1
1.5
—
—
—
0
0
16
141
1.14
0.14
1.7
2.2
3866.7
2332.7
u/l
—
8
58
8
98
0.81
0.13
4.3
3.9
—
—
—
0
0
8
99
0.81
0.13
1.3
1.4
—
—
—
0
0
8
99
0.81
0.13
1.3
1.4
—
—
—
0
0
8
99
0.81
0.13
1.3
1.4
—
—
—
0
0
8
100
0.80
0.13
1.6
1.6
—
—
—
0
0
15
169
0.89
0.12
6.1
3.4
4.7
4.3
e9/l
0.09
15
169
130
1261
1.04
0.12
1.4
1.4
—
—
—
0
0
37
395
0.93
0.12
1.2
1.3
—
—
—
0
0
18
199
0.90
0.11
1.4
1.7
2.7
5.5
iu/l
—
7
57
52
547
0.95
0.11
1.6
1.9
—
—
—
0
0
71
740
0.96
0.11
3.5
2.9
65.5
66.7
g/l
0.56
58
670
64
612
1.05
0.11
1.4
1.6
—
—
—
0
0
38
403
0.94
0.10
4.7
3.7
46.2
49.1
%
0.29
38
398
34
319
1.07
0.10
3.0
2.4
9.7
10.8
g/l
0.75
27
272
50
525
0.95
0.10
1.2
1.2
142.2
150.2
iu/ml
0.04
19
209
28
261
1.07
0.10
1.3
1.5
298.1
288.3
ug/g
0.10
17
154
5
44
1.14
0.10
1.6
1.4
—
—
—
0
0
55
526
1.05
0.10
1.3
1.5
—
—
—
0
0
5
45
1.11
0.10
1.0
1.1
—
—
—
0
0
10
114
0.88
0.09
1.0
1.0
—
—
—
0
0
14
155
0.90
0.09
1.4
1.2
—
—
—
0
0
18
165
1.09
0.08
1.7
1.7
—
—
—
0
0
20
216
0.92
0.08
1.6
1.7
—
—
—
0
0
5
62
0.81
0.08
2.0
1.6
—
—
—
0
0
5
63
0.79
0.08
1.6
1.6
—
—
—
0
0
40
419
0.95
0.08
3.3
2.5
0.7
0.6
%
0.75
40
404
9
85
1.06
0.07
3.0
2.4
—
—
—
0
0
13
118
1.10
0.07
1.2
1.1
—
—
—
0
0
8
92
0.87
0.06
1.6
1.6
—
—
—
0
0
279
2759
1.02
0.06
3.8
3.9
16.5
7.9
mg/mmol
0.36
162
1727
22
234
0.94
0.06
1.8
1.8
—
—
—
0
0
85
831
1.02
0.05
2.2
2.2
0.2
0.2
g/l
0.60
79
784
13
141
0.92
0.05
1.0
1.1
—
—
—
0
0
318
3153
1.01
0.05
4.1
4.1
—
—
—
0
0
20
190
1.05
0.04
1.2
1.3
—
—
—
0
0
24
230
1.04
0.03
5.5
3.6
1.6
1.6
mg/l
0.06
19
208
227
2254
1.01
0.03
2.4
2.7
352.7
6336.8
umol/l
7.60
195
1932
102
1007
1.01
0.03
1.6
1.8
—
—
—
0
0
20
209
0.96
0.03
1.6
1.7
—
—
—
0
0
12
128
0.94
0.02
3.3
2.3
7.6
35.8
u/ml
0.44
12
122
28
289
0.97
0.02
1.9
1.9
—
—
—
0
0
15
158
0.95
0.02
1.3
1.3
—
—
—
0
0
91
921
0.99
0.02
2.2
1.7
1.4
1.5
%
0.47
81
794
189
1901
0.99
0.01
1.6
1.7
441.2
25240046.9
pmol/l
1.67
149
1565
35
342
1.02
0.01
3.1
2.4
7.5
7.4
g/l
0.08
25
262
35
342
1.02
0.01
3.1
2.4
—
—
—
0
0
35
342
1.02
0.01
3.1
2.4
3.5
3.8
g/l
0.73
24
251
33
323
1.02
0.01
3.1
2.4
3.2
3.2
g/l
0.05
25
255
34
333
1.02
0.01
4.4
3.9
1.4
1.4
mmol/l
0.01
34
325
102
1012
1.01
0.01
1.6
1.8
—
—
—
0
0
12
114
1.05
0.00
2.1
1.8
—
—
—
0
0
11
116
0.95
0.00
3.7
2.0
33.6
32.7
pg
0.33
11
116
14
146
0.96
0.00
1.5
1.2
198.4
280.2
u/ml
—
9
82
181
1817
1.00
0.00
1.3
1.3
1.0
1.8
u/ml
0.98
40
481
40
394
1.02
0.00
1.6
1.8
1.7
1.5
g/l
0.67
34
347
90
906
0.99
0.00
3.4
3.5
—
—
—
0
0
25
246
1.02
0.00
1.1
1.2
—
—
—
0
0
11
108
1.02
0.00
1.3
1.5
—
—
—
0
0
12
122
0.98
0.00
1.3
1.3
—
—
—
0
0
12
122
0.98
0.00
1.3
1.3
—
—
—
0
0
14
138
1.01
0.00
1.7
1.3
—
—
—
0
0
23
228
1.01
0.00
1.3
1.6
—
—
—
0
0
25
248
1.01
0.00
1.1
1.1
—
—
—
0
0
146
1464
1.00
0.00
1.4
1.3
57.3
34.3
iu/ml
0.73
43
485
12
121
0.99
0.00
1.3
1.3
—
—
—
0
0
61
607
1.01
0.00
1.7
2.0
—
—
—
0
0
70
697
1.00
0.00
4.2
3.5
91.1
84.5
ng/l
0.20
60
612
10
105
0.95
0.00
1.0
1.3
—
—
—
0
0
5
51
0.98
0.00
2.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
5
51
0.98
0.00
2.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
8.0
—
0
5
12
120
1.00
0.00
1.3
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
20.9
—
0
5
19
190
1.00
0.00
1.2
1.3
—
—
—
0
0
5
49
1.02
0.00
1.2
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
38.3
—
0
5
12
120
1.00
0.00
1.3
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
12.4
—
0
9
5
49
1.02
0.00
1.2
1.6
—
—
—
0
0
12
120
1.00
0.00
1.3
1.3
—
—
—
0
0
5
49
1.02
0.00
1.2
1.6
—
—
—
0
0
5
49
1.02
0.00
1.2
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
0.00
1.2
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_CRANIAL_NERVE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_CRANIAL_NERVE | 1.104 [0.96, 1.27] | 0.176 |
| Birth year | 0.997 [0.99, 1.01] | 0.544 |
During the follow-up period (1.1.1998 — 31.12.2019), 312 out of 2291 females with CD2_BENIGN_CRANIAL_NERVE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_CRANIAL_NERVE | 0.893 [0.77, 1.04] | 0.151 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 296 out of 1846 males with CD2_BENIGN_CRANIAL_NERVE died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_CRANIAL_NERVE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.106% | 0.216% |
| 5 | 0.569% | 1.193% |
| 10 | 1.639% | 2.809% |
| 15 | 3.339% | 5.148% |
| 20 | 5.606% | 8.77% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_CRANIAL_NERVE – Benign neoplasm: Cranial nerves
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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