Benign neoplasm: Cranial nerves

CD2_BENIGN_CRANIAL_NERVE

cranial nerve malignant neoplasm: Benign and malignant neoplasms that arise from one or more of the twelve cranial nerves.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D33.3
  • Hospital discharge: ICD-9 2251
  • Hospital discharge: ICD-8 22403|2251
  • Cause of death: ICD-10 D33.3
  • Cause of death: ICD-9 2251
  • Cause of death: ICD-8 22403|2251

2 out of 7 registries used, show all original rules.

1063

4. Check minimum number of events

None

1063

5. Include endpoints

None

1063

6. Filter based on genotype QC (FinnGen only)

1034

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D33
Name in latin
Neoplasma benignum nervi cranialis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6100 3369 2687
Only index persons 5447 3043 2404
Unadjusted period prevalence (%)
Whole population 0.09 0.10 0.08
Only index persons 0.10 0.11 0.09
Median age at first event (years)
Whole population 56.38 56.92 55.69
Only index persons 55.98 56.46 55.36

-FinnGen-

Key figures

All Female Male
Number of individuals 1034 584 450
Unadjusted period prevalence (%) 0.21 0.21 0.21
Median age at first event (years) 56.99 56.06 58.19

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1063
Matched controls
10630
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D33.30
ICD-10 Finland
Acoustic neuroma
+∞
307.7
890
*
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
100.4
307.7
318
45
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
59.6
307.7
215
45
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
17.1
296.3
271
208
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
60.6
284.2
160
31
9560/0-C72.4
ICD-O-3
Schwannoma, NOS, of acoustic nerve
+∞
270.7
248
*
DFF00
NOMESCO Finland
Pure tone audiometry
8.8
243.2
398
678
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
8.3
187.5
295
470
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
43.3
180.6
109
28
Z01.1
ICD-10 Finland
Examination of ears and hearing
5.5
140.6
365
929
DFF59
NOMESCO Finland
Other assessment of balance
20.0
117.2
92
50
DFF15
NOMESCO Finland
Speech audiometry
7.4
115.1
185
294
G51.0
ICD-10 Finland
Bell palsy
11.3
106.6
117
115
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
4.3
105.9
386
1252
D33.39
ICD-10 Finland
Benign tumor of the cranial nerves UNS
+∞
95.3
90
*
D33.37
ICD-10 Finland
Another benign tumor of the cranial nerves
+∞
94.2
89
*
D33.3
ICD-10 Finland
Benign neoplasm: Cranial nerves
+∞
93.1
88
*
2251A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Cranial nerves
+∞
86.7
82
*
H02.2
ICD-10 Finland
Lagophthalmos
35.7
80.7
51
15
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
13.8
63.5
60
46
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
29.1
62.4
42
15
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
7.9
59.7
85
116
N07CA01
ATC
betahistine; oral
4.2
55.9
167
451
22510
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Cranial nerves (including optic)
+∞
55.7
53
*
AAE32
NOMESCO Finland
Translabyrinthine excision acoustic neurinome
+∞
52.5
50
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
6.7
51.6
85
136
WF099
NOMESCO Finland
Other radiotherapy
20.2
50.4
39
20
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
17.0
48.9
41
25
UDC00
NOMESCO Finland
Ear microscopy
4.0
48.3
151
420
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
171.0
47.2
49
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.8
46.4
160
476
AAE34
NOMESCO Finland
Other operations on acoustical nerv
+∞
44.1
42
*
9560/0-C72.5
ICD-O-3
Schwannoma, NOS, of cranial nerve, NOS
+∞
44.1
42
*
H93.1
ICD-10 Finland
Tinnitus
3.9
42.9
141
405
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
12.5
42.1
42
35
ZXC40
NOMESCO Finland
Use of ultrasound
17.2
42.0
35
21
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
3.9
40.2
130
369
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
207.6
39.1
40
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.3
38.4
161
541
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
8.6
31.0
40
48
Q85.01
ICD-10 Finland
Neurofibromatosis, type 2
+∞
30.4
29
*
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
3.7
30.3
102
296
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.5
28.5
226
1055
2152
FHL
Extraction, big brain
65.9
28.1
32
5
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.9
27.0
83
226
AA1AD
NOMESCO Finland
CT of head and brain
2.1
26.9
358
2065
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
143.7
26.7
28
*
ZXH01
NOMESCO Finland
Procedure performed within operation theatre
74.6
25.9
29
*
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
5.7
25.1
47
85
R42
ICD-10 Finland
Dizziness and giddiness
2.1
25.0
299
1649
D33.9
ICD-10 Finland
Benign neoplasm: Central nervous system, unspecified
255.9
24.8
25
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
9.6
23.6
28
30
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
4.2
23.4
64
160
WF002
NOMESCO Finland
Radical radiotherapy
3.3
23.3
93
301
R5120
NOMESCO Finland
Preparation of an aid
4.2
23.2
64
161
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
22.1
506
3462
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
6.1
21.8
38
64
ZX050
NOMESCO Finland
Stereotactic radiotherapy
8.6
21.1
27
32
DE2DG
NOMESCO Finland
Acoustic channel very extensive MRI examination with high intensity magnet
61.3
20.9
24
*
DE2CM
NOMESCO Finland
Acoustic channel extensive MRI examination with 3 Tesla magnet
22.0
20.9
30
14
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
20.6
314
1872
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
75.0
19.8
22
*
DAX08
NOMESCO Finland
Fitting of hearing aid
3.0
19.7
93
332
Z97.4
ICD-10 Finland
Presence of external hearing-aid
3.3
19.7
78
251
DC1AD
NOMESCO Finland
Temporalbone CT
8.5
19.3
25
30
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.6
19.0
65
190
9560/0-C72.9
ICD-O-3
Schwannoma, NOS, of nervous system, NOS
+∞
18.8
18
*
8000/0-C72.4
ICD-O-3
Neoplasm, benign of acoustic nerve
+∞
18.8
18
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
17.7
175
884
CBH25
NOMESCO Finland
Tarsorrhaphy
182.9
17.6
18
*
H02
ICPC
Hearing complaint
2.1
17.4
185
962
ZZC00
NOMESCO Finland
Graft of fascia
50.9
17.0
20
*
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
6.1
16.1
28
47
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.9
16.0
77
278
CBH30
NOMESCO Finland
Tarsorraphy
+∞
15.7
15
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.4
15.6
39
91
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
16.3
15.3
24
15
XX3DW
NOMESCO Finland
Time consuming IT work
2.2
15.0
144
718
R4110
NOMESCO Finland
Physiotherapy
1.8
14.8
316
2057
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
14.8
419
2949
DE2BM
NOMESCO Finland
Acoustic channel MRI examination with 3 Tesla magnet
81.3
14.6
16
*
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
81.3
14.6
16
*
QAJ10
NOMESCO Finland
Browlift
27.6
14.3
19
7
Q85.09
ICD-10 Finland
Unspecified neurofibromatosis
76.1
13.6
15
*
Q85.1
ICD-10 Finland
Tuberous sclerosis
+∞
13.6
13
*
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
17.0
13.0
20
12
G91.1
ICD-10 Finland
Obstructive hydrocephalus
13.2
12.9
22
17
H81.3
ICD-10 Finland
Other peripheral vertigo
3.5
12.9
44
129
TAB00
NOMESCO Finland
Lumbar puncture
2.9
12.7
62
225
H02.1
ICD-10 Finland
Ectropion of eyelid
6.1
12.6
22
37
3252
FHL
Repair with foreign material (spring, magnet)
+∞
12.5
12
*
D33.7
ICD-10 Finland
Benign neoplasm: Other specified parts of central nervous system
131.5
12.5
13
*
SPAT1043
SPAT
Audiometry
2.1
12.4
132
683
H02AB02
ATC
dexamethasone; systemic
2.0
12.2
139
736
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
3.5
12.2
41
119
G50.0
ICD-10 Finland
Trigeminal neuralgia
3.9
12.2
35
91
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.0
12.1
149
812
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
5.1
12.0
25
50
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
4.5
12.0
29
66
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
65.7
11.6
13
*
D33.03
ICD-10 Finland
Pilosytic lateral astrocytoma of the strobe brain
+∞
11.5
11
*
AAH50
NOMESCO Finland
Cranial nerve anastomosis
+∞
11.5
11
*
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.0
11.1
121
630
D32.04
ICD-10 Finland
Secondary or multiple benign tumor of the meninges above the exam
43.8
10.9
13
*
D33.2
ICD-10 Finland
Benign neoplasm: Brain, unspecified
43.8
10.9
13
*
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
4.5
10.8
26
59
N03AF01
ATC
carbamazepine; oral, rectal
2.5
10.7
68
283
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
10.4
287
1972
Z3226
NOMESCO Finland
Physiotherapist
1.7
10.4
200
1250
D32.01
ICD-10 Finland
Benign tumor of meninges on interhemispheric surface
10.7
10.3
19
18
H91.8
ICD-10 Finland
Other specified hearing loss
5.0
10.3
22
45
ZXA05
NOMESCO Finland
Left side
1.6
10.3
274
1867
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
10.1
128
704
D33.45
ICD-10 Finland
Benign Schwannom in the nerve root of the spinal cord
40.5
10.0
12
*
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
20.2
9.8
14
7
D32.05
ICD-10 Finland
Cerebral meninges
20.2
9.8
14
7
DFF40
NOMESCO Finland
Otoneurologic examination of vertigo
10.7
9.8
18
17
Q85.0
ICD-10 Finland
Neurofibromatosis (nonmalignant)
100.9
9.4
10
*
Z31.5
ICD-10 Finland
Genetic counselling
2.6
9.4
56
226
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
10.8
9.3
17
16
R51.80
ICD-10 Finland
Headache
1.8
9.2
155
932
WX402
NOMESCO Finland
General anaesthesia
1.6
8.9
212
1398
9530/0-C70.9
ICD-O-3
Meningioma, NOS, of meninges, NOS
24.2
8.9
12
5
R4135
NOMESCO Finland
Rehabilitation for hearing problems
3.5
8.8
30
88
H81.0
ICD-10 Finland
Ménière disease
3.2
8.7
34
109
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
50.4
8.7
10
*
N76
ICPC
Neoplasm nervous system unspecified
50.4
8.7
10
*
N03AF02
ATC
oxcarbazepine; oral
2.9
8.7
41
147
H53.4
ICD-10 Finland
Visual field defects
3.5
8.5
29
85
XCK00
NOMESCO Finland
Perimetry
2.2
8.5
73
347
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
27.8
8.5
11
*
CBF99
NOMESCO Finland
Other operation for ectropion
20.2
8.5
12
6
ZZK00
NOMESCO Finland
Graft of nerve
90.8
8.4
9
*
CBK10
NOMESCO Finland
Operation for lagophtalmus
+∞
8.3
8
*
ABB10
NOMESCO Finland
Resection of lesion of spinal canal
+∞
8.3
8
*
QAJ20
NOMESCO Finland
Subperiosteal facelift
+∞
8.3
8
*
D33.0
ICD-10 Finland
Benign neoplasm: Brain, supratentorial
+∞
8.3
8
*
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
22.2
8.0
11
5
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
8.0
708
6107
G50.1
ICD-10 Finland
Atypical facial pain
3.6
8.0
26
74
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.0
8.0
34
115
ZXC95
NOMESCO Finland
Use of surgical navigator
4.5
7.9
19
43
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
7.9
123
722
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
8.5
7.8
16
19
H47.1
ICD-10 Finland
Papilloedema, unspecified
8.5
7.8
16
19
XA800
NOMESCO Finland
Neuropsychological investigation
2.5
7.7
46
187
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
7.6
79
404
QAJ30
NOMESCO Finland
Other facelift
18.5
7.6
11
6
CBW99
NOMESCO Finland
Other operation on eyelid
25.2
7.6
10
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
7.4
365
2807
D43.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Cranial nerves
+∞
7.3
7
*
3259
FHL
Other measure in this category
+∞
7.3
7
*
DQE20
NOMESCO Finland
Implantation of foreign material in vocal chord
+∞
7.3
7
*
ZZF00
NOMESCO Finland
Graft of adipose tissue
5.8
7.2
19
33
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
4.0
7.2
20
51
N75
ICPC
Benign neoplasm nervous system
30.2
7.2
9
*
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
6.6
7.1
17
26
H53.1
ICD-10 Finland
Subjective visual disturbances
2.1
7.0
69
348
CBN30
NOMESCO Finland
Shortening of canthal ligament
8.3
6.8
14
17
ABB00
NOMESCO Finland
Excision of lesion of spinal canal
40.3
6.8
8
*
2151
FHL
Resection, big brain
40.3
6.8
8
*
DE2CF
NOMESCO Finland
Acoustic channel extensive MRI examination with median intensity magnet
40.3
6.8
8
*
H16.0
ICD-10 Finland
Corneal ulcer
2.2
6.7
55
258
D32.07
ICD-10 Finland
Secondary or multiple benign tumor of the meninges below the exam
22.7
6.7
9
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
6.7
206
1438
H29
ICPC
Ear symptom/complaint other
1.7
6.6
116
703
D33
ICD-10 Finland
Benign neoplasm of brain and other parts of central nervous system
70.3
6.4
7
*
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
5.2
6.3
18
35
RK520, ,
NOMESCO Finland
9.3
6.3
12
13
C72.3
ICD-10 Finland
Malignant neoplasm: Optic nerve
+∞
6.3
6
*
H93.3
ICD-10 Finland
Disorders of acoustic nerve
+∞
6.3
6
*
D33.08
ICD-10 Finland
Another benign tumor of the cerebral ventricle
+∞
6.3
6
*
D33.15
ICD-10 Finland
Another benign tumor of the cerebellum
+∞
6.3
6
*
9560/0-C71.9
ICD-O-3
Schwannoma, NOS, of brain, NOS
+∞
6.3
6
*
3253
FHL
Tarsoraphy
+∞
6.3
6
*
C72.4
ICD-10 Finland
Malignant neoplasm: Acoustic nerve
+∞
6.3
6
*
ZZQ30
NOMESCO Finland
Free microvascular graft of muscle
+∞
6.3
6
*
TQA05
NOMESCO Finland
Puncture of skin of head or neck
26.8
6.2
8
*
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
7.1
6.2
14
20
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
6.2
177
1215
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
8.7
6.1
12
14
RK320, ,
NOMESCO Finland
6.1
6.0
15
25

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
409
2851
1.71
15.06
2.0
2.4
—
—
—
0
0
337
2271
1.71
13.80
3.7
3.9
93.21
90.22
%
1.49
332
2210
547
4183
1.63
13.65
6.2
5.8
1.22
1.21
mmol/l
0.59
506
3806
572
4570
1.54
10.81
7.0
6.6
1.22
1.21
mmol/l
0.55
502
3884
311
2184
1.60
10.30
1.9
2.3
—
—
—
0
0
114
605
1.99
9.94
2.4
2.5
26.70
24.96
au/ml
—
10
34
643
5323
1.53
9.93
5.0
4.8
6.58
6.75
mmol/l
1.37
619
5000
105
548
2.02
9.59
1.3
1.3
22.32
60.39
au/ml
—
6
34
170
1037
1.76
9.58
7.2
7.5
0.81
1.18
mmol/l
0.48
122
828
169
1038
1.75
9.29
7.2
7.5
5.11
5.12
kpa
0.01
159
1000
169
1038
1.75
9.29
7.2
7.5
15.91
12.08
kpa
10.43
158
1000
137
817
1.78
8.31
1.2
1.4
—
—
—
0
0
50
205
2.51
8.17
1.7
1.2
83.23
29.26
e6/l
0.36
39
159
50
205
2.51
8.17
1.9
1.3
2161.86
677.63
e6/l
0.35
42
165
985
9182
1.99
8.05
17.9
17.1
139.90
139.68
mmol/l
1.85
967
8947
46
183
2.58
8.00
1.7
1.2
—
—
—
0
0
451
3592
1.44
7.70
2.2
2.1
—
—
—
0
0
984
9207
1.93
7.38
18.1
17.2
3.95
3.98
mmol/l
2.53
966
8962
512
4212
1.42
7.12
2.4
2.6
—
—
—
0
0
949
8814
1.72
6.89
14.9
14.7
24.53
24.32
mg/l
0.06
775
7046
27
91
3.02
6.42
2.2
1.1
—
—
—
0
0
687
6107
1.35
5.15
4.3
4.4
—
—
—
0
0
443
3704
1.34
4.97
2.3
2.2
78.72
77.72
nmol/l
0.34
392
3290
990
9436
1.72
4.79
11.0
10.7
25.93
25.99
u/l
0.03
961
9099
732
6650
1.32
4.25
4.1
4.2
11.38
12.59
mm/h
1.36
670
6122
546
4769
1.30
4.25
5.7
6.3
12.14
11.55
umol/l
0.35
523
4534
873
8153
1.40
4.17
4.9
4.7
1.87
2.10
mu/l
0.87
790
7403
24
98
2.48
4.07
2.1
1.1
—
—
—
0
0
762
6984
1.32
4.02
7.5
7.6
77.88
78.90
u/l
0.22
717
6549
1013
9772
1.78
3.93
22.6
21.7
249.87
248.90
e9/l
0.18
990
9523
1013
9775
1.77
3.88
22.6
21.7
90.67
91.25
fl
4.19
1004
9628
1013
9777
1.77
3.85
22.7
21.7
4.51
4.47
e12/l
1.70
991
9501
1013
9779
1.76
3.82
22.8
21.9
134.91
134.85
g/l
0.05
1006
9626
1012
9773
1.74
3.72
22.7
21.8
6.66
6.72
e9/l
0.46
989
9495
1012
9776
1.73
3.67
22.6
21.6
30.19
30.36
pg
2.56
1003
9627
1011
9771
1.71
3.56
23.0
21.8
40.42
40.00
%
1.85
957
9116
86
572
1.55
3.47
10.1
9.1
0.65
0.68
%
0.28
86
566
454
3941
1.27
3.47
4.2
4.6
35.78
35.36
g/l
0.88
421
3676
494
4338
1.26
3.40
9.6
15.2
1.18
1.25
inr
1.36
132
1250
335
2809
1.28
3.38
2.3
2.1
176.05
231.15
u/l
0.95
320
2649
86
577
1.53
3.35
10.0
9.0
1.12
1.34
%
2.18
86
571
85
572
1.53
3.27
10.2
9.2
94.86
93.92
%
0.44
85
566
463
4053
1.25
3.22
6.2
5.9
0.66
0.68
%
0.30
423
3778
479
4212
1.25
3.20
6.0
5.7
57.45
57.47
%
0.01
443
3950
485
4274
1.25
3.17
6.3
6.0
27.96
27.41
%
0.50
446
4006
6
8
7.53
3.05
1.8
1.5
—
—
—
0
0
212
1697
1.31
3.02
3.4
3.0
0.70
0.76
ug/l
0.36
140
1114
573
5160
1.24
3.02
8.4
9.1
4.17
4.13
e9/l
0.15
483
4529
473
4176
1.24
2.98
6.2
5.8
2.76
2.86
%
0.41
430
3901
473
4192
1.23
2.83
6.6
6.1
8.69
8.70
%
0.01
434
3919
498
4440
1.23
2.81
6.0
5.7
0.04
0.04
e9/l
0.10
411
3857
14
53
2.66
2.80
1.7
1.3
19.14
18.91
nmol/l
0.03
14
47
507
4530
1.23
2.80
6.1
5.7
1.84
1.94
e9/l
0.65
427
4022
496
4431
1.22
2.71
6.0
5.7
0.59
0.59
e9/l
0.13
409
3844
269
2249
1.26
2.71
5.8
6.7
—
—
—
0
0
33
184
1.82
2.63
1.5
1.3
12.89
10.68
u/l
0.24
21
149
428
3790
1.22
2.50
2.1
2.0
95.57
95.37
pmol/l
0.03
230
1938
109
813
1.38
2.49
4.3
6.9
9.07
9.56
mmol/l
0.32
102
776
509
4585
1.21
2.49
6.3
6.0
0.19
0.19
e9/l
0.16
423
4048
154
1213
1.32
2.46
4.5
5.4
1.01
1.03
mmol/l
0.53
143
1113
209
1714
1.27
2.46
3.0
3.0
2.46
2.45
mmol/l
0.28
177
1504
626
5761
1.21
2.43
3.2
3.2
46.66
50.48
u/l
0.56
584
5354
21
104
2.04
2.37
1.4
1.4
249.56
353.45
pmol/l
1.24
16
94
467
4189
1.20
2.35
6.7
6.2
—
—
—
0
0
953
9197
1.35
2.33
14.0
14.0
—
—
—
0
0
5
9
5.58
2.21
1.0
1.0
—
—
—
0
0
5
9
5.58
2.21
2.6
2.6
58.36
89.63
pmol/l
—
5
9
315
2736
1.22
2.19
4.3
3.9
7.40
7.40
ph
0.06
51
537
354
3119
1.20
2.11
3.4
3.4
2.36
2.35
mmol/l
0.30
295
2727
68
482
1.44
2.11
10.9
9.8
—
—
—
0
0
722
6780
1.20
2.09
4.1
3.9
14.86
14.86
pmol/l
0.03
649
6127
182
1502
1.26
2.03
3.1
3.2
0.83
0.81
mmol/l
1.20
171
1406
331
2915
1.20
1.96
5.8
5.0
3.33
2.72
ug/l
0.25
295
2600
772
7315
1.20
1.94
19.1
19.2
332.34
332.22
g/l
0.14
767
7266
321
2822
1.20
1.93
2.8
3.2
—
—
—
0
0
800
7608
1.21
1.92
18.2
17.5
15.04
15.10
%
0.09
790
7477
325
2864
1.19
1.90
3.4
3.3
35.67
32.66
u/l
0.31
309
2732
42
276
1.54
1.89
3.3
3.0
—
—
—
0
0
97
749
1.32
1.82
8.9
8.3
—
—
—
0
0
117
933
1.29
1.75
4.7
4.2
—
—
—
0
0
912
8812
1.25
1.74
4.6
4.6
4.70
4.65
mmol/l
0.65
834
8119
906
8752
1.24
1.71
4.6
4.5
1.48
1.47
mmol/l
0.30
820
8008
8
31
2.59
1.66
1.5
2.2
—
—
—
0
0
128
1040
1.26
1.65
1.4
1.3
—
—
—
0
0
627
5879
1.16
1.63
4.7
4.6
711.20
2339.92
e6/l
—
10
93
48
671
0.70
1.62
1.2
1.4
—
—
—
0
0
54
388
1.41
1.61
1.2
1.2
—
—
—
0
0
6
20
3.01
1.58
1.2
1.1
—
—
—
0
0
79
610
1.32
1.52
2.3
2.2
11.84
13.03
nmol/l
0.61
68
543
181
1543
1.21
1.51
2.8
2.8
1.29
1.19
e6/l
0.13
94
891
9
37
2.44
1.48
3.1
3.3
27.67
33.04
umol/l
—
9
27
169
1435
1.21
1.47
2.9
3.0
2.35
2.24
e6/l
0.07
86
786
16
87
1.85
1.46
2.3
3.0
—
—
—
0
0
673
6380
1.15
1.40
3.6
4.0
—
—
—
0
0
7
29
2.42
1.39
1.4
1.4
—
—
—
0
0
428
3937
1.15
1.38
10.1
9.6
0.00
0.00
e9/l
0.10
334
3247
302
2711
1.16
1.37
3.3
3.3
60.54
99.48
e6/l
0.61
226
2101
279
2499
1.16
1.30
3.3
3.2
0.37
0.46
e6/l
0.23
206
1911
18
106
1.71
1.30
1.7
1.3
—
—
nmol/l
—
0
0
11
55
2.01
1.27
1.6
1.3
153.19
173.21
pmol/l
0.23
11
55
923
8988
1.20
1.27
5.2
5.1
2.78
2.74
mmol/l
0.78
839
8232
36
253
1.44
1.25
1.1
1.1
—
—
—
0
0
131
1104
1.21
1.25
1.4
1.4
—
—
—
0
0
43
316
1.38
1.18
2.4
1.8
22.05
21.59
s
0.26
37
283
249
2230
1.15
1.16
1.5
1.5
21.28
20.72
nmol/l
0.22
198
1874
124
1050
1.20
1.14
1.7
1.7
—
—
—
0
0
206
1825
1.16
1.12
3.0
2.9
560.58
542.91
mosm/kgh2o
0.45
168
1579
268
2425
1.14
1.08
3.2
3.1
—
—
—
0
0
100
835
1.22
1.07
2.6
2.5
31.80
41.65
u/l
0.74
87
712
870
8461
1.16
1.05
4.1
4.1
1.27
1.30
mmol/l
0.59
773
7683
343
3164
1.12
1.02
3.8
3.8
139.18
117.83
e6/l
0.08
244
2265
0
30
0.00
0.97
0.0
1.3
—
97.92
—
0
22
153
1341
1.16
0.97
1.2
1.2
—
—
—
0
0
26
182
1.44
0.96
1.8
2.0
5.16
4.84
mmol/24h
0.18
19
160
62
498
1.26
0.96
2.7
3.3
4.52
4.50
pmol/l
0.05
57
428
0
32
0.00
0.95
0.0
1.1
—
327.47
—
0
19
138
1202
1.17
0.95
1.3
1.3
737.78
491.85
titre
0.60
27
260
9
52
1.74
0.92
3.7
2.3
—
—
—
0
0
59
474
1.26
0.92
2.5
2.4
—
—
—
0
0
6
28
2.15
0.91
1.5
1.3
—
—
—
0
0
27
193
1.41
0.91
2.1
2.2
131.00
128.81
g/l
0.15
18
144
300
2766
1.12
0.89
4.3
3.9
—
—
—
0
0
38
289
1.33
0.89
5.4
6.3
1.33
1.26
mmol/l
0.13
31
256
6
31
1.94
0.84
1.3
1.1
—
—
—
0
0
891
8715
1.14
0.83
4.9
4.7
5.83
5.98
mmol/l
4.05
791
7898
252
2317
1.11
0.79
1.3
1.4
—
—
—
0
0
462
4382
1.10
0.78
3.7
3.8
0.00
0.00
estimate
0.50
82
801
0
28
0.00
0.76
0.0
1.2
—
45.51
—
0
14
456
4330
1.09
0.74
5.1
5.2
0.00
0.00
estimate
-0.00
81
832
370
3480
1.10
0.74
3.4
3.5
6.31
5.84
ph
1.47
26
238
847
8277
1.11
0.73
5.9
6.0
39.20
40.11
mmol/mol
2.13
764
7634
14
207
0.67
0.73
3.4
3.3
0.66
0.85
nmol/l
—
8
164
7
39
1.80
0.72
1.3
1.9
0.96
6.28
nmol/l
—
7
31
29
220
1.33
0.72
2.0
1.4
299.03
284.93
mu/l
0.14
29
198
308
2879
1.10
0.70
2.4
2.5
62.25
88.81
u/l
0.46
285
2670
16
110
1.46
0.68
1.8
1.2
—
—
—
0
0
22
162
1.37
0.66
3.8
2.7
—
—
—
0
0
22
292
0.75
0.64
1.0
1.1
—
—
—
0
0
23
172
1.34
0.64
1.6
1.6
—
—
—
0
0
5
29
1.73
0.64
1.2
1.1
—
—
—
0
0
13
87
1.50
0.63
1.5
1.5
—
—
—
0
0
37
298
1.25
0.61
4.3
3.6
36.10
46.21
mg/l
0.25
29
246
37
298
1.25
0.61
4.2
3.6
51.47
71.15
mg/l
0.37
29
244
22
165
1.34
0.60
2.6
1.6
—
—
—
0
0
180
1958
0.90
0.60
1.7
1.6
1.24
1.21
mg/l
0.02
130
1497
0
22
0.00
0.59
0.0
1.6
—
—
—
0
0
8
54
1.49
0.57
1.7
1.5
—
—
—
0
0
6
36
1.67
0.56
2.3
3.4
—
—
—
0
0
47
395
1.20
0.54
1.6
1.8
—
—
—
0
0
20
151
1.33
0.54
1.5
1.4
—
—
—
0
0
451
4330
1.07
0.52
3.7
3.8
0.00
0.00
estimate
0.75
88
886
10
66
1.52
0.52
1.3
1.5
—
—
—
0
0
10
146
0.68
0.52
1.0
1.1
—
12.55
—
0
10
93
830
1.13
0.52
2.8
2.1
362.82
375.28
nmol/l
0.22
83
766
15
109
1.38
0.51
2.7
3.6
—
—
—
0
0
137
1253
1.11
0.50
2.2
2.3
23.77
22.34
%
0.38
115
1079
9
65
1.39
0.50
2.6
1.5
78.78
80.75
umol/l
—
9
65
17
127
1.34
0.49
1.4
1.2
1.56
5.58
u/ml
—
9
53
243
2285
1.08
0.49
2.2
2.1
3.01
3.08
mg/l
0.17
206
1937
204
1905
1.09
0.49
2.7
2.6
5.08
5.67
e6/l
0.31
177
1728
32
387
0.82
0.48
2.0
1.7
—
—
—
0
0
7
47
1.49
0.47
4.1
6.7
—
—
—
0
0
260
2748
0.93
0.47
2.7
3.0
1364.18
1274.38
ng/l
0.11
226
2343
10
68
1.48
0.47
1.1
1.1
—
—
—
0
0
7
48
1.46
0.47
1.4
1.4
—
—
—
0
0
7
48
1.46
0.47
1.3
1.3
6.67
5.78
ug/l
—
7
41
187
1744
1.09
0.47
3.9
3.9
118.50
333.30
ng/l
2.40
152
1377
15
111
1.36
0.47
1.8
1.3
—
—
—
0
0
11
153
0.72
0.45
1.1
1.1
—
—
—
0
0
5
84
0.59
0.45
1.0
1.1
—
—
—
0
0
247
2333
1.08
0.45
3.6
3.5
—
—
—
0
0
112
1022
1.11
0.44
2.3
2.2
149.05
131.40
ug/g
0.20
86
815
68
602
1.14
0.44
3.6
3.8
7.41
7.40
ph
—
10
76
129
1186
1.10
0.44
1.3
1.3
—
—
—
0
0
15
197
0.76
0.44
3.1
3.5
13.70
27.92
mg/l
—
7
120
144
1333
1.09
0.43
2.0
2.3
2.33
2.33
g/l
0.00
128
1236
11
78
1.41
0.43
1.5
1.4
—
—
—
0
0
221
2341
0.93
0.43
4.3
4.2
0.00
0.00
estimate
0.50
80
806
15
113
1.33
0.42
3.5
2.6
—
—
—
0
0
77
856
0.89
0.41
3.7
3.4
1.92
1.93
mmol/l
0.00
69
713
73
814
0.89
0.41
2.7
2.4
6.07
7.29
ug/l
0.57
62
723
8
58
1.38
0.41
1.9
2.0
2.57
2.20
ug/l
—
8
49
0
16
0.00
0.41
0.0
2.3
—
235.00
—
0
6
0
16
0.00
0.41
0.0
1.1
—
0.75
—
0
11
11
79
1.40
0.41
1.0
1.3
—
—
—
0
0
24
195
1.24
0.40
4.3
3.7
—
—
—
0
0
0
17
0.00
0.40
0.0
2.1
—
16.34
—
0
17
65
579
1.13
0.40
1.3
1.2
—
—
—
0
0
388
3739
1.06
0.39
2.8
2.7
127.45
136.22
ug/l
0.19
355
3426
10
137
0.73
0.39
3.1
2.4
—
—
—
0
0
143
1333
1.08
0.38
1.9
2.0
—
—
—
0
0
185
1743
1.07
0.37
1.7
1.7
1098.92
1194.10
nmol/l
0.78
138
1298
60
671
0.89
0.37
3.9
4.2
0.12
0.54
%
0.44
17
193
26
216
1.21
0.37
1.3
1.5
—
—
—
0
0
26
216
1.21
0.37
1.3
1.5
—
—
—
0
0
18
143
1.26
0.37
1.4
1.5
—
—
—
0
0
24
198
1.22
0.36
1.3
1.5
—
—
—
0
0
11
81
1.36
0.36
1.1
1.2
—
—
—
0
0
11
146
0.75
0.36
1.1
1.0
—
—
—
0
0
12
90
1.34
0.36
1.6
1.8
—
—
—
0
0
26
217
1.20
0.35
1.3
1.5
—
—
—
0
0
26
217
1.20
0.35
1.3
1.5
—
—
—
0
0
65
585
1.12
0.35
3.6
3.1
4.19
6.72
e9/l
1.28
44
462
31
264
1.18
0.35
1.1
1.2
—
658.57
—
0
7
154
1446
1.08
0.35
2.0
2.3
12.91
12.79
umol/l
0.05
138
1346
110
1020
1.09
0.34
2.5
2.7
6.95
8.49
umol/l
0.83
102
885
44
387
1.14
0.34
3.7
4.2
24.41
24.92
mmol/l
0.91
39
368
6
45
1.34
0.33
1.0
1.2
—
—
—
0
0
368
3556
1.05
0.33
3.4
3.7
39.10
49.72
ng/l
0.22
256
2580
10
133
0.75
0.33
6.5
2.2
—
—
—
0
0
14
177
0.79
0.33
1.1
1.2
—
—
—
0
0
6
86
0.70
0.33
1.3
1.4
4.50
6.74
mmol/l
—
6
80
6
89
0.67
0.33
1.2
1.1
—
—
—
0
0
40
455
0.87
0.33
3.2
3.3
25.56
25.29
mmol/l
0.22
40
444
24
201
1.20
0.32
1.2
1.3
104.27
240.22
miu/ml
—
9
95
28
327
0.85
0.32
1.1
1.2
0.24
1.37
u/ml
—
7
23
43
381
1.13
0.30
2.3
2.6
—
—
—
0
0
12
152
0.79
0.29
1.5
2.7
—
—
—
0
0
106
990
1.08
0.29
3.9
4.3
14.93
23.94
ug/l
0.33
86
823
51
460
1.11
0.28
3.6
3.6
—
—
—
0
0
67
614
1.10
0.28
5.2
4.7
—
—
—
0
0
27
233
1.16
0.27
1.5
1.7
11157.32
13733.51
e6/l
0.17
22
172
212
2031
1.05
0.27
3.4
3.8
—
—
—
0
0
70
759
0.92
0.27
3.8
4.1
0.77
0.99
%
0.55
26
279
35
310
1.13
0.26
1.5
1.5
—
—
—
0
0
70
757
0.92
0.25
2.9
2.9
125.89
189.24
ng/l
1.31
62
694
39
349
1.12
0.25
1.0
1.1
—
—
—
0
0
9
77
1.17
0.24
1.6
1.2
—
—
—
0
0
109
1028
1.07
0.24
2.3
2.5
1.80
1.82
%
0.05
97
913
26
227
1.15
0.24
2.4
2.5
—
—
—
0
0
5
38
1.32
0.23
1.2
1.1
—
—
—
0
0
184
1916
0.95
0.23
3.9
4.2
1.02
1.02
kg/l
0.20
22
266
12
97
1.24
0.23
1.3
1.7
—
—
—
0
0
28
247
1.14
0.23
4.9
4.6
—
—
—
0
0
11
88
1.25
0.22
1.0
1.2
—
—
—
0
0
18
153
1.18
0.22
1.7
2.1
3539.06
2773.93
u/l
—
9
64
21
242
0.87
0.22
2.9
2.3
83.62
87.35
ug/min
0.03
13
144
49
534
0.91
0.22
1.7
1.6
—
—
—
0
0
39
430
0.90
0.22
4.1
3.4
24.66
24.18
mmol/l
0.34
39
420
22
191
1.16
0.22
2.3
2.4
15.85
15.97
%
0.04
13
99
53
575
0.92
0.22
3.9
3.0
133.58
128.06
g/l
1.22
53
564
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
74
692
1.07
0.21
3.6
2.9
10.95
10.80
g/l
0.07
67
633
142
1484
0.95
0.21
1.3
1.3
31.80
13.80
u/ml
0.30
52
560
11
89
1.24
0.21
1.5
1.3
—
35.67
—
0
6
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
16
187
0.85
0.20
7.0
3.7
56.69
57.29
%
0.05
16
187
0
14
0.00
0.20
0.0
1.1
—
1.46
—
0
9
268
2757
0.96
0.20
3.1
3.2
323.26
230.95
mg/l
0.12
157
1755
15
127
1.18
0.19
2.2
2.6
—
—
—
0
0
37
337
1.10
0.19
2.9
2.4
9.52
10.67
g/l
0.82
29
297
14
118
1.19
0.19
1.1
1.0
2.73
2.55
u/ml
—
6
47
32
289
1.11
0.19
6.2
9.7
—
—
—
0
0
10
81
1.24
0.18
3.0
2.4
—
—
—
0
0
33
299
1.11
0.18
2.9
2.3
38.09
37.94
g/l
0.05
25
260
100
951
1.06
0.18
1.6
1.6
—
—
—
0
0
42
386
1.09
0.18
1.9
2.0
2.20
2.03
ug/l
0.05
35
345
240
2468
0.96
0.18
1.6
1.7
1.32
1.38
mmol/l
0.52
206
2055
7
59
1.19
0.18
2.0
2.2
—
—
—
0
0
19
216
0.88
0.17
1.4
1.3
—
—
—
0
0
59
552
1.07
0.17
3.5
1.7
2.08
1.43
g/l
0.55
51
505
52
557
0.93
0.17
1.2
1.2
137.22
160.36
iu/ml
0.15
20
230
302
3089
0.97
0.17
3.0
2.9
—
—
—
0
0
22
196
1.13
0.16
4.3
2.5
—
—
—
0
0
20
225
0.89
0.16
1.5
1.3
—
—
—
0
0
8
71
1.13
0.16
1.4
1.1
—
—
—
0
0
55
586
0.94
0.16
3.0
3.0
—
—
—
0
0
11
92
1.20
0.16
1.0
1.1
—
—
—
0
0
65
688
0.94
0.16
3.5
4.0
0.35
0.63
%
1.27
26
238
48
448
1.07
0.15
3.6
3.9
—
—
—
0
0
85
891
0.95
0.15
1.7
1.5
—
—
—
0
0
31
284
1.09
0.15
4.6
3.9
3.85
3.89
mmol/l
0.17
31
279
8
96
0.83
0.13
1.1
2.1
—
—
—
0
0
24
218
1.10
0.13
5.7
3.9
—
—
—
0
0
40
374
1.07
0.13
4.8
4.6
—
—
—
0
0
80
766
1.05
0.13
3.2
3.7
—
—
—
0
0
90
865
1.04
0.12
2.2
2.2
0.22
0.21
g/l
0.90
84
815
19
171
1.11
0.12
2.7
2.7
—
—
—
0
0
16
179
0.89
0.12
6.4
3.3
4.70
4.29
e9/l
0.11
16
179
11
126
0.87
0.11
1.2
1.1
—
—
—
0
0
189
1932
0.97
0.11
1.3
1.3
1.02
1.73
u/ml
0.98
42
505
45
475
0.95
0.11
1.3
1.3
—
—
—
0
0
69
719
0.96
0.11
3.8
4.2
0.04
0.11
%
0.89
25
239
240
2357
1.02
0.10
2.4
2.7
351.91
6553.55
umol/l
8.28
206
2044
11
125
0.88
0.10
1.2
1.1
—
—
—
0
0
66
687
0.96
0.10
1.2
1.2
—
—
—
0
0
72
693
1.04
0.10
1.5
1.4
—
—
—
0
0
287
2914
0.98
0.10
3.8
3.8
16.79
7.94
mg/mmol
0.39
167
1821
30
281
1.07
0.09
1.3
1.5
307.94
291.18
ug/g
0.19
18
166
5
47
1.06
0.09
1.0
1.3
123.60
152.68
nmol/l
—
5
47
16
145
1.11
0.09
1.9
1.9
—
—
—
0
0
14
126
1.11
0.09
1.3
1.2
—
—
—
0
0
6
57
1.05
0.08
1.8
3.2
—
—
—
0
0
20
215
0.93
0.07
1.5
1.7
4.72
5.87
iu/l
—
8
63
6
72
0.83
0.07
1.0
1.1
—
—
—
0
0
19
176
1.08
0.07
1.3
1.2
—
—
—
0
0
102
1045
0.97
0.07
1.6
1.5
—
—
—
0
0
12
108
1.11
0.07
1.1
1.2
—
—
—
0
0
8
91
0.88
0.06
1.4
1.4
—
—
—
0
0
8
92
0.87
0.06
1.4
1.4
—
—
—
0
0
8
93
0.86
0.06
1.4
1.5
—
—
—
0
0
8
93
0.86
0.06
1.8
2.1
—
—
—
0
0
83
851
0.97
0.06
1.7
1.5
—
—
—
0
0
61
592
1.03
0.06
1.2
1.4
—
—
—
0
0
11
121
0.91
0.06
3.7
2.0
33.64
32.52
pg
0.41
11
121
12
131
0.92
0.05
1.1
1.1
1.90
2.14
u/ml
—
6
69
198
2005
0.98
0.05
1.7
1.7
43312537.50
27801762.55
pmol/l
0.14
157
1651
253
2506
1.01
0.05
4.0
4.3
—
—
—
0
0
66
676
0.97
0.05
1.3
1.4
—
—
—
0
0
25
239
1.05
0.04
1.1
1.2
—
—
—
0
0
42
408
1.03
0.04
1.6
1.8
1.70
1.55
g/l
0.47
35
359
35
339
1.03
0.03
2.5
3.4
0.35
0.29
g/l
0.29
13
137
76
773
0.98
0.03
3.4
2.9
65.36
66.77
g/l
0.67
62
699
47
459
1.03
0.03
1.7
1.4
—
—
—
0
0
122
1233
0.99
0.02
1.8
1.7
—
—
—
0
0
172
1706
1.01
0.02
1.8
1.4
2.31
2.51
g/l
0.74
102
1009
10
107
0.93
0.02
1.4
1.1
—
—
—
0
0
288
2891
0.99
0.01
3.0
3.1
7.57
7.40
mmol/l
0.28
243
2421
17
163
1.04
0.01
1.2
1.6
—
—
—
0
0
22
213
1.03
0.01
1.6
1.6
—
—
—
0
0
155
1541
1.01
0.01
1.4
1.3
54.02
34.87
iu/ml
0.62
46
514
74
748
0.99
0.01
4.7
4.0
—
—
—
0
0
65
657
0.99
0.01
3.3
2.5
—
—
—
0
0
74
733
1.01
0.01
4.2
3.5
89.03
84.31
ng/l
0.15
64
645
25
244
1.03
0.00
5.6
3.6
1.57
1.59
mg/l
0.03
20
221
34
346
0.98
0.00
4.4
3.9
1.41
1.41
mmol/l
0.01
34
338
11
114
0.96
0.00
1.1
1.1
0.90
0.75
u/ml
—
5
50
12
116
1.03
0.00
1.4
1.5
32.27
32.66
g/l
0.05
12
106
14
144
0.97
0.00
1.1
1.1
—
—
—
0
0
27
266
1.02
0.00
1.1
1.2
—
—
—
0
0
10
98
1.02
0.00
2.7
2.3
0.58
1.48
g/24h
—
5
47
12
122
0.98
0.00
1.2
1.1
—
—
—
0
0
15
148
1.01
0.00
1.5
1.5
—
—
—
0
0
16
158
1.01
0.00
1.3
1.3
—
—
—
0
0
11
109
1.01
0.00
1.4
1.2
—
—
—
0
0
11
111
0.99
0.00
1.1
1.1
0.04
1.72
u/ml
—
5
57
15
153
0.98
0.00
1.5
1.2
198.44
278.24
u/ml
—
9
85
20
203
0.98
0.00
5.8
4.4
2.72
2.65
mmol/l
0.05
15
136
77
769
1.00
0.00
3.1
2.6
72.38
70.95
e9/l
0.13
58
591
16
155
1.03
0.00
5.3
1.4
—
—
—
0
0
10
95
1.05
0.00
1.3
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.8
—
—
—
0
0
9
96
0.94
-0.00
1.4
1.7
—
—
—
0
0
7
75
0.93
-0.00
2.0
1.9
1.33
1.34
e9/l
—
7
69
5
52
0.96
-0.00
1.0
1.0
—
—
—
0
0
6
64
0.94
-0.00
2.0
1.9
25.93
36.52
%
—
6
64
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
69
0.87
-0.00
9.8
1.6
11.28
11.06
%
—
6
69
9
96
0.94
-0.00
1.3
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
1.90
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
83
0.96
-0.00
1.1
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_CRANIAL_NERVE and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_CRANIAL_NERVE 1.104 [0.96, 1.27] 0.176
Birth year 0.997 [0.99, 1.01] 0.544

During the follow-up period (1.1.1998 — 31.12.2019), 312 out of 2291 females with CD2_BENIGN_CRANIAL_NERVE died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_CRANIAL_NERVE 0.893 [0.77, 1.04] 0.151
Birth year 0.987 [0.98, 1.0] 0.008

During the follow-up period (1.1.1998 — 31.12.2019), 296 out of 1846 males with CD2_BENIGN_CRANIAL_NERVE died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_CRANIAL_NERVE.

N-year risk Females Males
1 0.106% 0.216%
5 0.569% 1.193%
10 1.639% 2.809%
15 3.339% 5.148%
20 5.606% 8.77%

Relationships between endpoints

Index endpoint: CD2_BENIGN_CRANIAL_NERVE – Benign neoplasm: Cranial nerves

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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