This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Acute lymphocytic leukaemia, helper endpoint
HLP_C3_ALL
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
237 |
4. Check minimum number of eventsNone |
237 |
5. Include endpointsNone |
237 |
6. Filter based on genotype QC (FinnGen only) |
237 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Acute lymphocytic leukaemia, helper endpoint
based on the number of shared cases.
Similar with more cases:
- Acute lymphocytic leukaemia
- Acute lymphocytic leukaemia, excluding all cancers (controls excluding all cancers)
- Any event in cancer register
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 237 | 132 | 105 |
| Unadjusted period prevalence (%) | 0.05 | 0.04 | 0.05 |
| Median age at first event (years) | 9.23 | 6.99 | 12.05 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 237
- Matched controls
- 2368
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
8615.7
309.6
229
6
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
+∞
268.8
204
*
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
+∞
237.1
186
*
L01BB02
ATC
mercaptopurine; oral
495.0
167.1
149
8
H02AB02
ATC
dexamethasone; systemic
305.5
137.2
128
9
TAB00
NOMESCO Finland
Lumbar puncture
80.3
125.6
139
41
XW000
NOMESCO Finland
Bone marrow biopsy
116.4
101.2
105
16
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
136.2
100.1
102
13
H02AB09
ATC
hydrocortisone; systemic
66.1
97.5
111
31
Z85.6
ICD-10 Finland
Personal history of leukaemia
+∞
81.0
73
*
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
23.0
68.8
105
79
L03AA02
ATC
filgrastim; parenteral
418.6
64.8
62
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
77.2
64.2
71
13
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
347.4
55.7
54
*
A04AA01
ATC
ondansetron; systemic, rectal
53.0
53.4
63
16
2040A
ICD-9 Finland
Lymphoid leukaemia, Acute
+∞
53.1
49
*
9811/3-C42.1
ICD-O-3
B lymphoblastic leukemia/lymphoma, NOS, of bone marrow
+∞
50.9
47
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
55.8
47.9
56
13
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
30.2
46.7
63
28
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
+∞
45.3
42
*
ZX131
NOMESCO Finland
Intrathecal
+∞
41.9
39
*
A41.9
ICD-10 Finland
Sepsis, unspecified
36.8
39.3
50
17
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
13.7
38.5
70
70
WW500
NOMESCO Finland
Blood transfusion
26.0
35.8
50
24
R50.9
ICD-10 Finland
Fever, unspecified
7.0
34.8
103
234
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
34.2
32
*
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
23.7
33.5
48
25
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
+∞
33.1
31
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
32.0
30
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
10.6
32.0
66
83
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
357.4
31.6
31
*
J05AB11
ATC
valaciclovir; oral
8.6
31.5
75
121
ZX114
NOMESCO Finland
Intramuscular
68.0
31.0
35
6
H02AB06
ATC
prednisolone; systemic
5.1
30.7
148
581
20400
ICD-8 Finland
Lymphatic leukaemia, Acute
+∞
28.7
27
*
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
316.8
28.4
28
*
127
Kela drug reimbursment
Transplant complication
21.3
27.8
41
23
A05AA02
ATC
ursodeoxycholic acid; oral
29.0
27.6
37
15
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
26.6
25
*
1XX02
NOMESCO Finland
NA
+∞
26.6
25
*
J02AC01
ATC
fluconazole; systemic
4.5
25.3
128
493
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
24.4
23
*
9101
FHL
Bone biopsy
96.9
24.2
26
*
K03.66
ICD-10 Finland
Tooth plaque
6.2
23.8
71
152
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
+∞
23.3
22
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
6.3
23.2
68
142
M04AA01
ATC
allopurinol; systemic
11.9
22.5
42
42
ZX121
NOMESCO Finland
Central venous catheter
88.7
22.1
24
*
A04AA02
ATC
granisetron; systemic, transdermal
88.7
22.1
24
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
4.4
20.8
91
292
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
4.9
20.6
77
211
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
19.0
18
*
121
Kela drug reimbursment
Severe hypofunction of sexual glands
22.3
18.2
26
13
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.5
18.0
74
219
2301
FHL
Lumbar puncture in anesthesia or operating room
+∞
17.9
17
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
17.9
17
*
ZX120
NOMESCO Finland
Intravenous
6.8
17.8
47
83
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
193.8
17.8
18
*
A06AD11
ATC
lactulose; oral
5.9
17.6
52
107
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
34.4
17.4
22
7
J05AB01
ATC
aciclovir; systemic
4.2
16.9
75
237
L03AA10
ATC
lenograstim; parenteral
+∞
16.9
16
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.4
16.8
69
203
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
170.7
15.7
16
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
41.0
15.6
19
5
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.2
15.1
105
468
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
5.6
14.8
45
95
L01BB03
ATC
tioguanine; oral
+∞
14.7
14
*
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
+∞
14.7
14
*
9109
FHL
Other measure in this category
+∞
14.7
14
*
A01AB09
ATC
miconazole; local oral
5.9
14.6
42
83
ZXA00
NOMESCO Finland
Right side
3.8
14.2
69
233
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
79.8
13.7
15
*
N02AA05
ATC
oxycodone; systemic
7.7
13.7
32
47
G62.0
ICD-10 Finland
Drug-induced polyneuropathy
+∞
13.7
13
*
A02BC01
ATC
omeprazole; systemic
3.5
13.4
74
272
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.7
13.2
34
58
XF400
NOMESCO Finland
ECG with 12 standard connections
3.6
13.2
66
227
J01MA12
ATC
levofloxacin; systemic
4.5
13.1
50
134
JN4BD
NOMESCO Finland
Extensive body CT
10.6
13.1
25
26
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.9
13.1
115
586
R4110
NOMESCO Finland
Physiotherapy
3.2
12.7
81
330
L04AA01
ATC
[U] ciclosporin; systemic
21.5
12.7
18
9
C90.0
ICD-10 Finland
Multiple myeloma
+∞
12.6
12
*
2AX04
NOMESCO Finland
NA
136.9
12.6
13
*
602
Kela drug reimbursment
Children's severe malnutrition
10.1
11.8
23
25
C95.9
ICD-10 Finland
Leukaemia, unspecified
+∞
11.5
11
*
L01XE06
ATC
[U] dasatinib; systemic
+∞
11.5
11
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
11.5
11
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
11.5
11
*
Z92.6
ICD-10 Finland
Personal history of chemotherapy for neoplastic disease
+∞
11.5
11
*
J02AC03
ATC
voriconazole; systemic
125.8
11.5
12
*
ZX108
NOMESCO Finland
Inhalation
18.9
10.9
16
9
D64.9
ICD-10 Finland
Anaemia, unspecified
5.5
10.8
32
65
L04AA06
ATC
mycophenolic acid; systemic
10.8
10.7
20
20
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
10.6
81
367
WW409
NOMESCO Finland
Other aferesis
114.8
10.5
11
*
1CX01
NOMESCO Finland
NA
+∞
10.5
10
*
J02AC04
ATC
posaconazole; systemic
+∞
10.5
10
*
B73
ICPC
Leukaemia
+∞
10.5
10
*
WW304
NOMESCO Finland
Transfer of stem cells from registered domestic donator
+∞
10.5
10
*
150
Kela drug reimbursment
Dasatinib
+∞
10.5
10
*
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
8.5
10.4
22
28
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
8.5
10.4
22
28
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.5
10.1
102
543
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.7
10.0
25
41
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
8.4
9.9
21
27
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
15.9
9.6
15
10
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
6.0
9.5
26
48
0388X
ICD-9 Finland
Septicaemia, Other specified septicaemias
31.4
9.5
12
*
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
31.4
9.5
12
*
L04AD01
ATC
ciclosporin; systemic
9.3
9.5
19
22
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
9.4
9
*
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
+∞
9.4
9
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
9.4
9
*
2AA01
NOMESCO Finland
NA
+∞
9.4
9
*
A01AB04
ATC
amphotericin B; local oral
8.9
9.3
19
23
FM2CE
NOMESCO Finland
NA
5.2
9.2
28
59
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
38.3
9.1
11
*
M87.1
ICD-10 Finland
Osteonecrosis due to drugs
93.2
8.5
9
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
7.5
8.4
19
27
Z08.2
ICD-10 Finland
Follow-up examination after chemotherapy for malignant neoplasm
+∞
8.4
8
*
WB133
NOMESCO Finland
Very demanding adjuvant cytostatic therapy
+∞
8.4
8
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
+∞
8.4
8
*
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
+∞
8.4
8
*
WF002
NOMESCO Finland
Radical radiotherapy
+∞
8.4
8
*
5639
FHL
Other measure in this category
+∞
8.4
8
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.6
8.1
36
111
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
8.1
55
228
Z31.6
ICD-10 Finland
General counselling and advice on procreation
15.7
7.8
12
8
5604
FHL
Vascular preparation or cannulation in the operating room
46.5
7.8
9
*
A03FA01
ATC
metoclopramide; systemic, rectal
3.5
7.7
36
115
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
26.0
7.6
10
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
82.5
7.5
8
*
ZXA05
NOMESCO Finland
Left side
2.8
7.5
50
206
A07AA02
ATC
nystatin; oral
5.5
7.4
21
41
189
Kela drug reimbursment
Imatinib
+∞
7.3
7
*
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
5.6
7.3
20
38
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
20.8
7.2
10
5
ZXA10
NOMESCO Finland
Bilateral
2.7
7.1
50
211
SAA03
NOMESCO Finland
Extended examination of mouth
2.1
7.1
131
880
EBA15
NOMESCO Finland
Extraction of large number of teeth
6.2
7.1
18
31
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
9.7
6.9
13
14
QXB05
NOMESCO Finland
Skin wound assessment, unspecified location
23.3
6.7
9
*
IEP04
NOMESCO Finland
Focused parenting intervention
23.3
6.7
9
*
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
12.7
6.6
11
9
A98
ICPC
Health maint/preventive medicine
0.3
6.5
199
2225
M87.3
ICD-10 Finland
Other secondary osteonecrosis
71.7
6.5
7
*
J01MA14
ATC
moxifloxacin; systemic
4.6
6.4
21
49
K02.0
ICD-10 Finland
Caries limited to enamel
2.2
6.4
74
404
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.1
6.4
19
40
B02.9
ICD-10 Finland
Zoster without complication
5.1
6.4
19
40
TGC00
NOMESCO Finland
Bronchial lavation
11.5
6.4
11
10
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
5.6
6.3
17
32
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
6.3
6
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
6.3
6
*
L01AA01
ATC
cyclophosphamide; systemic
+∞
6.3
6
*
D32.01
ICD-10 Finland
Benign tumor of meninges on interhemispheric surface
+∞
6.3
6
*
115
Kela drug reimbursment
Breast cancer
+∞
6.3
6
*
324
Kela drug reimbursment
Dasatinib
+∞
6.3
6
*
4CJ01
NOMESCO Finland
NA
+∞
6.3
6
*
C90.1
ICD-10 Finland
Plasma cell leukaemia
+∞
6.3
6
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
8.0
6.2
13
17
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.2
6.2
18
37
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
13.0
6.1
10
8
WW200
NOMESCO Finland
Immunization
5.8
6.1
16
29
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
10.4
6.1
11
11
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
7.6
6.0
13
18
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
41
26
18.86
48.93
4.4
1.5
—
—
—
0
0
34
15
26.30
47.37
3.4
1.7
—
—
—
0
0
42
33
15.25
44.64
5.0
1.5
—
—
—
0
0
37
23
18.88
44.45
6.4
2.3
6.6
11.3
%
1.37
27
18
42
35
14.37
43.09
4.4
1.4
—
—
—
0
0
34
19
20.72
42.87
3.3
1.5
—
—
—
0
0
50
57
10.85
41.74
13.3
1.3
29.1
89.7
e6/l
0.86
45
52
50
57
10.85
41.74
13.3
1.2
10.0
6.5
e6/l
0.15
45
50
34
22
17.88
39.92
8.3
2.0
663.8
543.1
e6/l
0.38
26
17
65
112
7.62
38.54
2.9
1.8
8.4
13.6
iu/l
1.17
50
95
32
21
17.46
37.24
6.9
2.4
—
—
—
0
0
39
37
12.42
36.75
17.2
9.2
326.2
447.0
iu/ml
—
10
5
64
114
7.32
36.68
3.0
1.9
6.8
8.0
u/l
0.33
46
96
34
32
12.24
32.07
3.9
3.8
51.5
53.8
%
0.37
34
32
34
32
12.24
32.07
2.9
3.7
3.2
3.8
e9/l
0.68
34
32
32
29
12.60
30.88
4.6
1.9
—
—
—
0
0
27
19
15.91
30.13
7.6
1.8
34.6
23.0
%
2.51
27
19
43
68
7.50
27.11
1.6
1.7
—
—
—
0
0
40
68
6.87
23.47
2.0
1.7
97.4
105.6
u/ml
—
8
9
27
7
43.21
22.25
1.2
1.0
—
—
—
0
0
57
143
4.93
21.99
3.2
1.6
—
—
—
0
0
57
146
4.82
21.40
3.3
1.7
—
—
—
0
0
64
182
4.45
21.04
13.9
3.8
4.4
7.1
umol/l
1.02
56
147
43
88
5.75
20.84
1.6
1.7
—
—
—
0
0
21
18
12.70
20.74
4.7
1.3
—
—
—
0
0
71
226
4.06
19.97
17.4
2.7
31.0
29.9
s
0.70
71
221
41
85
5.62
19.55
1.5
1.8
114.7
171.6
u/ml
1.33
28
44
24
28
9.42
19.23
4.2
1.2
—
—
—
0
0
30
47
7.16
18.86
1.7
1.5
0.3
0.4
nmol/l
0.77
23
40
64
202
3.97
18.06
4.4
1.8
—
—
—
0
0
25
35
7.87
17.30
2.9
1.3
—
—
—
0
0
71
264
3.41
15.45
3.0
3.8
623.2
1070.7
ng/l
1.04
58
218
18
20
9.66
14.85
2.7
1.1
—
—
—
0
0
38
94
4.62
14.64
4.4
1.5
—
—
—
0
0
110
543
2.91
14.50
16.8
6.0
35.4
37.2
g/l
2.37
104
513
82
357
2.98
13.43
11.8
2.0
1.8
0.9
mg/l
1.39
67
258
51
171
3.53
12.87
1.7
3.4
25.6
23.3
%
0.42
46
161
168
1081
2.90
12.73
56.8
7.2
2.9
3.9
e9/l
11.77
159
931
15
17
9.35
12.13
1.2
1.1
—
—
—
0
0
13
12
11.40
12.06
6.6
1.2
33.9
34.2
pg
0.06
13
12
129
744
2.61
11.88
27.7
8.1
1.2
1.2
mmol/l
0.34
111
670
16
21
8.10
11.56
1.6
1.6
—
—
—
0
0
120
678
2.56
11.41
27.1
8.3
1.2
1.2
mmol/l
0.17
115
632
42
135
3.57
11.23
3.7
2.1
13.0
13.0
nmol/l
0.00
34
118
21
39
5.81
11.09
2.3
1.2
—
—
—
0
0
21
39
5.81
11.09
2.3
1.2
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
20
37
5.81
10.59
8.7
4.9
0.3
0.3
u/ml
0.18
14
25
144
909
2.49
10.48
18.0
5.2
6.1
6.6
mmol/l
1.96
137
823
15
8
19.90
10.40
6.9
2.1
—
—
—
0
0
15
8
19.90
10.40
6.9
2.1
—
—
—
0
0
13
16
8.54
9.83
5.8
3.4
—
—
—
0
0
53
215
2.89
9.56
3.5
2.3
339.1
379.6
nmol/l
0.87
53
205
13
8
17.09
8.65
1.9
1.0
—
—
—
0
0
8
0
+∞
8.38
11.4
0.0
—
—
—
0
0
95
541
2.26
8.23
12.7
2.9
31.6
30.6
u/l
0.22
95
523
11
6
19.13
7.67
5.9
1.7
—
—
—
0
0
69
363
2.27
7.07
11.3
2.0
—
—
—
0
0
11
8
14.34
6.96
8.0
5.8
—
—
—
0
0
10
14
7.41
6.75
1.6
1.0
—
—
—
0
0
10
14
7.41
6.75
2.9
1.4
—
—
—
0
0
94
568
2.09
6.74
5.3
3.8
—
—
—
0
0
12
22
5.69
6.35
1.2
1.5
—
—
—
0
0
6
0
+∞
6.27
12.2
0.0
—
—
—
0
0
6
0
+∞
6.27
4.0
0.0
—
—
—
0
0
6
0
+∞
6.27
1.0
0.0
—
—
—
0
0
10
8
12.98
6.14
1.3
1.0
—
—
—
0
0
80
477
2.02
5.79
4.9
3.8
0.1
0.3
e6/l
0.68
67
355
10
17
6.10
5.67
1.1
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
11
21
5.44
5.58
1.4
1.1
—
—
—
0
0
8
6
13.73
5.11
12.9
3.5
—
—
—
0
0
12
28
4.46
4.88
1.6
1.7
—
—
—
0
0
13
35
3.87
4.43
2.0
1.7
—
—
—
0
0
69
426
1.87
4.35
2.1
3.0
2.5
2.7
mg/l
0.34
61
367
7
6
11.97
4.30
1.4
2.2
—
—
—
0
0
104
732
1.75
4.22
13.8
3.8
—
—
—
0
0
27
117
2.48
4.20
12.2
12.9
0.7
0.5
mmol/l
0.11
18
90
18
63
3.01
4.16
2.4
1.7
—
—
—
0
0
28
129
2.33
3.82
1.9
1.6
353.9
318.2
mu/l
0.22
28
123
38
199
2.08
3.81
42.9
5.5
24.3
23.7
mmol/l
1.07
38
192
20
79
2.67
3.74
1.5
1.3
—
—
—
0
0
44
248
1.95
3.60
38.2
5.2
1.9
1.5
mmol/l
0.44
39
187
7
9
7.97
3.58
5.3
6.6
—
—
—
0
0
7
9
7.97
3.58
5.3
6.7
—
—
—
0
0
6
6
10.21
3.51
10.2
1.0
—
—
—
0
0
6
6
10.21
3.51
10.2
1.0
—
—
—
0
0
6
6
10.21
3.51
10.2
1.0
—
—
—
0
0
8
14
5.87
3.37
2.5
1.6
—
—
—
0
0
14
48
3.04
3.36
1.5
1.0
—
—
—
0
0
29
148
2.09
3.11
1.8
1.3
125.0
334.8
u/ml
0.66
24
140
8
16
5.13
3.07
1.6
1.7
—
—
—
0
0
182
1563
1.71
3.03
3.9
3.5
2.7
2.8
mmol/l
0.27
177
1461
5
5
10.17
2.99
1.2
1.0
—
—
—
0
0
22
103
2.25
2.91
6.0
2.4
—
—
—
0
0
9
22
4.21
2.91
1.4
1.1
—
—
—
0
0
18
77
2.45
2.90
6.3
3.1
1.2
1.2
mmol/l
0.34
18
66
6
9
6.80
2.88
4.5
10.4
—
—
—
0
0
6
9
6.80
2.88
10.5
1.2
—
—
—
0
0
6
9
6.80
2.88
10.5
1.2
—
—
—
0
0
6
9
6.80
2.88
10.5
1.2
—
—
—
0
0
6
9
6.80
2.88
10.5
1.2
—
—
—
0
0
138
1119
1.56
2.81
5.5
4.1
83.7
295.8
e6/l
—
7
13
20
92
2.28
2.76
2.4
1.8
102.8
80.6
ml/min/173m2
—
8
38
47
296
1.73
2.69
4.3
3.5
0.7
0.7
e6/l
0.09
29
169
7
15
4.77
2.61
9.9
1.3
—
—
—
0
0
7
15
4.77
2.61
9.9
1.3
—
—
—
0
0
7
15
4.77
2.61
9.9
1.3
—
—
—
0
0
171
1905
0.63
2.45
62.7
11.3
37.7
40.5
%
4.93
138
1599
9
27
3.42
2.42
5.1
1.3
—
—
—
0
0
62
432
1.59
2.41
2.5
2.9
18.6
31.9
ng/l
1.04
40
223
7
17
4.21
2.38
1.0
1.0
—
—
—
0
0
152
1732
0.66
2.37
3.9
3.8
—
—
—
0
0
6
13
4.70
2.28
2.0
3.8
73.8
145.5
ug/l
—
6
13
45
293
1.66
2.28
4.5
3.6
2.7
3.1
e6/l
0.13
26
166
5
9
5.65
2.22
1.2
1.6
—
—
—
0
0
5
10
5.08
2.08
1.2
1.0
—
—
—
0
0
33
206
1.70
1.96
7.5
7.7
1.6
0.9
mmol/l
1.10
26
143
5
11
4.62
1.95
2.2
1.2
—
—
—
0
0
7
22
3.25
1.89
1.7
1.3
—
—
—
0
0
39
564
0.63
1.88
2.1
2.5
—
—
—
0
0
8
29
2.82
1.81
1.0
1.0
—
—
—
0
0
37
525
0.65
1.61
2.0
2.3
—
—
—
0
0
7
26
2.74
1.59
1.3
1.0
—
—
—
0
0
5
15
3.38
1.53
8.4
1.3
—
—
—
0
0
5
15
3.38
1.53
8.4
1.3
—
—
—
0
0
5
15
3.38
1.53
1.4
1.5
—
—
—
0
0
5
15
3.38
1.53
1.0
1.0
—
—
—
0
0
5
15
3.38
1.53
8.4
1.3
—
—
—
0
0
7
28
2.54
1.46
1.0
1.1
—
—
—
0
0
208
2180
0.63
1.46
68.1
14.3
128.9
136.5
g/l
7.49
208
2147
5
16
3.17
1.44
8.4
1.3
—
—
—
0
0
5
16
3.17
1.44
8.4
1.3
—
—
—
0
0
5
16
3.17
1.44
8.4
1.3
—
—
—
0
0
5
16
3.17
1.44
1.2
1.6
—
—
—
0
0
188
1725
1.43
1.44
62.6
12.3
13.7
13.2
%
4.63
188
1691
162
1451
1.37
1.43
23.0
7.5
100.7
96.5
ml/min/173m2
1.38
144
1082
13
67
1.99
1.41
20.5
12.9
0.8
0.7
%
0.57
13
67
27
176
1.60
1.39
8.5
8.1
24.9
24.2
mmol/l
1.29
27
171
37
260
1.50
1.38
3.3
3.4
135.8
752.9
ng/l
0.81
25
164
85
695
1.35
1.36
2.2
1.8
—
—
—
0
0
5
17
2.98
1.36
1.2
1.5
—
—
—
0
0
13
68
1.96
1.36
20.5
12.8
1.6
1.6
%
0.01
13
68
13
68
1.96
1.36
20.5
12.9
95.2
94.1
%
0.55
13
68
204
1908
1.50
1.34
36.0
7.2
35.3
26.1
u/l
4.97
204
1843
56
435
1.38
1.23
3.5
3.5
0.0
0.0
estimate
0.50
17
157
11
194
0.55
1.15
1.5
1.5
—
—
—
0
0
7
34
2.09
1.03
1.1
1.1
—
—
—
0
0
14
84
1.71
1.00
1.1
1.5
—
—
—
0
0
99
867
1.24
0.88
3.9
3.5
0.0
0.0
estimate
0.00
18
152
98
858
1.24
0.87
5.6
4.9
0.0
0.0
estimate
0.00
18
160
6
31
1.96
0.85
1.2
1.1
—
—
—
0
0
32
242
1.37
0.84
1.5
1.5
388.7
436.5
pmol/l
0.34
26
216
6
32
1.90
0.82
1.0
1.1
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
97
856
1.23
0.79
3.6
3.4
0.0
0.0
estimate
0.00
16
157
60
506
1.25
0.74
2.0
1.7
104.0
96.6
pmol/l
0.43
34
265
7
119
0.58
0.69
1.9
2.0
—
—
—
0
0
5
93
0.53
0.68
2.8
1.5
—
—
—
0
0
6
105
0.56
0.63
2.5
1.6
—
—
—
0
0
73
640
1.20
0.62
3.7
3.3
—
—
—
0
0
18
242
0.72
0.61
1.7
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.5
—
—
—
0
0
0
22
0.00
0.59
0.0
1.5
—
4.6
—
0
16
17
124
1.40
0.57
1.1
1.4
361.6
278.6
miu/ml
—
5
67
21
272
0.75
0.57
1.1
1.3
1.1
8.4
u/ml
—
8
103
11
156
0.69
0.51
1.8
1.2
—
—
—
0
0
17
127
1.36
0.51
12.9
5.8
—
—
—
0
0
14
187
0.73
0.47
4.2
3.3
19.3
24.7
%
—
5
76
7
48
1.47
0.47
1.6
1.5
—
—
—
0
0
8
117
0.67
0.47
1.9
1.7
—
—
—
0
0
5
33
1.53
0.41
1.0
1.2
—
—
—
0
0
158
1508
1.14
0.41
4.6
3.1
5.6
5.7
mmol/l
0.17
153
1378
6
46
1.31
0.33
1.5
1.9
1.5
0.6
nmol/l
—
6
39
6
46
1.31
0.33
14.3
2.0
—
—
—
0
0
194
1888
1.15
0.33
46.6
9.9
18.3
21.2
mg/l
0.81
170
1358
20
167
1.22
0.29
2.3
2.4
24779.8
4662.4
u/l
—
6
67
7
57
1.23
0.29
1.1
1.2
—
—
—
0
0
7
57
1.23
0.29
1.1
2.2
—
—
—
0
0
9
117
0.76
0.28
1.4
1.5
—
—
—
0
0
9
117
0.76
0.28
1.4
1.5
—
—
—
0
0
9
117
0.76
0.28
1.4
1.5
—
—
—
0
0
9
117
0.76
0.28
1.4
1.5
—
—
—
0
0
15
181
0.82
0.26
1.1
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
4.8
—
—
—
0
0
5
43
1.17
0.21
1.0
1.1
—
12.6
—
0
8
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
6
49
1.23
0.20
2.0
1.5
—
—
—
0
0
6
51
1.18
0.19
5.2
3.5
23.6
22.9
mmol/l
—
6
44
30
330
0.90
0.18
2.0
2.0
—
—
—
0
0
5
68
0.73
0.17
2.4
1.1
—
—
—
0
0
5
69
0.72
0.17
2.4
1.1
—
—
—
0
0
11
129
0.85
0.15
1.5
1.5
—
—
—
0
0
9
83
1.09
0.15
1.1
1.4
—
—
—
0
0
30
279
1.09
0.12
1.1
1.3
10.0
31.8
iu/ml
—
6
84
5
47
1.07
0.09
5.0
1.9
—
—
—
0
0
6
54
1.11
0.09
1.3
1.3
—
—
—
0
0
6
57
1.05
0.08
1.0
1.9
49.3
42.0
u/l
—
6
52
20
187
1.08
0.06
1.2
1.2
182.8
137.3
iu/ml
0.28
12
71
10
91
1.10
0.04
1.3
1.2
—
—
—
0
0
33
319
1.04
0.04
1.8
1.4
—
—
—
0
0
12
128
0.93
0.02
2.6
1.8
—
—
—
0
0
66
651
1.02
0.02
1.4
1.6
0.7
2.4
u/ml
2.05
19
140
11
106
1.04
0.00
1.6
1.6
—
—
—
0
0
27
266
1.02
0.00
1.6
1.9
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
17.7
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
516.0
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
12.2
—
—
—
0
0
6
69
0.87
0.00
1.0
1.1
—
14.9
—
0
8
9
96
0.94
0.00
2.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
4.4
—
1.3
—
0
8
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: HLP_C3_ALL – Acute lymphocytic leukaemia, helper endpoint
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).