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Molar incisor enamel hypoplasia, with caries

Endpoint Browser PheWeb

K11_MIH_CARIES

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

  • K11_CARIES
12851

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

3 out of 7 registries used, show all original rules.

266

4. Check minimum number of events

None

266

5. Include endpoints

266

6. Filter based on genotype QC (FinnGen only)

266

Control definitions (FinnGen only)

Control conditions
not K11_CARIES

Extra metadata

First used in FinnGen datafreeze
DF10

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2382 1118 1261
Only index persons 1584 754 830
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.04
Only index persons 0.03 0.03 0.03
Median age at first event (years)
Whole population 8.86 8.93 8.74
Only index persons 11.23 11.43 11.04

-FinnGen-

Key figures

All Female Male
Number of individuals 266 135 131
Unadjusted period prevalence (%) 0.05 0.05 0.06
Median age at first event (years) 8.41 8.84 7.97

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
232
Matched controls
2320
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
551.6
236.3
218
63
127
Kela drug reimbursment
Transplant complication
142.2
92.6
94
11
H02AB09
ATC
hydrocortisone; systemic
33.3
87.8
120
72
K02.0
ICD-10 Finland
Caries limited to enamel
22.3
85.5
200
508
WX404
NOMESCO Finland
Intravenous generell anesthesy
20.1
83.9
194
469
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
48.7
83.2
101
36
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
38.6
79.2
102
46
K03.66
ICD-10 Finland
Tooth plaque
16.0
76.7
159
277
EBA15
NOMESCO Finland
Extraction of large number of teeth
78.5
74.4
82
16
H02AB04
ATC
methylprednisolone; systemic
44.9
71.5
88
31
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
32.2
69.0
93
47
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
101.4
66.7
71
10
Z94.0
ICD-10 Finland
Kidney transplant status
110.4
66.5
70
9
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
17.1
63.9
112
120
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
13.6
63.7
131
201
R4110
NOMESCO Finland
Physiotherapy
11.3
61.5
167
428
WX408
NOMESCO Finland
General anesthesy, balanced
12.2
61.2
188
601
ZX120
NOMESCO Finland
Intravenous
17.5
60.3
103
101
L04AX01
ATC
azathioprine; systemic
28.7
59.9
83
44
A11CC03
ATC
alfacalcidol; systemic
47.9
54.8
66
19
205
Kela drug reimbursment
Chronic hypertension
39.6
50.9
64
22
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
63.9
50.8
58
12
XF602
NOMESCO Finland
Bloodpressure monitoring
40.6
50.4
63
21
GD1AA
NOMESCO Finland
Thorax X-ray examination
8.5
49.3
157
457
C08CA01
ATC
amlodipine; oral
34.8
47.8
62
24
L04AD01
ATC
ciclosporin; systemic
31.5
47.3
63
27
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
26.6
47.1
66
34
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
81.1
46.4
51
8
Z01.0
ICD-10 Finland
Examination of eyes and vision
8.1
45.5
134
333
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.9
44.9
137
357
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
9.6
44.9
107
189
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
56.1
42.0
49
11
SAA04
NOMESCO Finland
Special inverstigation of mouth
8.6
42.0
109
217
SCE00
NOMESCO Finland
Fissure closure of tooth
7.2
41.9
143
424
L04AA06
ATC
mycophenolic acid; systemic
34.8
41.8
54
20
TPH04
NOMESCO Finland
Cathetrisation of vein
8.4
41.7
111
229
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
14.5
41.0
73
71
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
14.3
40.7
73
72
L04AA01
ATC
[U] ciclosporin; systemic
165.1
40.2
41
*
602
Kela drug reimbursment
Children's severe malnutrition
14.7
39.7
70
66
XF400
NOMESCO Finland
ECG with 12 standard connections
6.9
39.3
132
373
ZXA00
NOMESCO Finland
Right side
8.4
39.1
101
195
137
Kela drug reimbursment
Uraemia requiring dialysis
67.4
38.9
44
8
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
28.2
38.8
53
24
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
53.9
37.5
44
10
K06.18
ICD-10 Finland
Another gingival hyperplasia
46.1
37.2
45
12
C03CA01
ATC
furosemide; systemic
18.9
37.1
58
40
SAA03
NOMESCO Finland
Extended examination of mouth
11.6
36.3
216
1246
K00.41
ICD-10 Finland
Prenatal enamel hypoplasia
44.8
36.2
44
12
Z94.4
ICD-10 Finland
Liver transplant status
405.2
36.0
35
*
B03XA01
ATC
erythropoietin; parenteral
61.8
35.8
41
8
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
90.1
35.0
38
5
TPH07
NOMESCO Finland
Cathetrisation of artery
8.9
35.0
83
136
A12AA04
ATC
calcium carbonate; oral
49.3
34.4
41
10
B05DA
ATC
Isotonic solutions
75.2
34.2
38
6
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
6.5
34.0
111
288
A41.9
ICD-10 Finland
Sepsis, unspecified
17.2
34.0
55
41
FM2CE
NOMESCO Finland
NA
8.2
33.8
85
152
WX882
NOMESCO Finland
High dependency care
7.2
33.8
97
211
C08CA02
ATC
felodipine; oral
106.1
33.8
36
*
RD210
NOMESCO Finland
NA
8.1
33.2
84
151
K03.00
ICD-10 Finland
Approximal wear
18.3
33.0
52
36
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
10.3
32.2
68
90
R50.9
ICD-10 Finland
Fever, unspecified
5.5
31.5
128
423
5AB14
NOMESCO Finland
NA
184.6
31.5
32
*
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
12.4
31.3
59
62
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
14.6
30.6
53
46
V03AG01
ATC
sodium cellulose phosphate; systemic
58.5
30.3
35
7
WW500
NOMESCO Finland
Blood transfusion
18.7
30.2
47
31
ZXA10
NOMESCO Finland
Bilateral
5.8
30.2
106
292
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
42.3
29.4
36
10
Z49.2
ICD-10 Finland
Other dialysis
56.6
29.3
34
7
KAC00
NOMESCO Finland
Nephrectomy
56.6
29.3
34
7
ZXA05
NOMESCO Finland
Left side
7.1
29.2
81
163
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
88.7
28.5
31
*
K03.64
ICD-10 Finland
Dental calculus supragingival
4.9
28.5
142
565
B05DB
ATC
Hypertonic solutions
164.9
28.3
29
*
XW000
NOMESCO Finland
Bone marrow biopsy
16.1
28.0
46
35
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.6
27.9
99
271
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
25.6
26.6
37
17
Z99.2
ICD-10 Finland
Dependence on renal dialysis
82.2
26.5
29
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
4.9
26.2
113
378
C07AB02
ATC
metoprolol; systemic
14.4
26.1
45
38
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
40.9
26.0
32
9
TK800
NOMESCO Finland
Hemodialysis
79.1
25.4
28
*
BE00A
NOMESCO Finland
NA
63.3
24.6
28
5
C03DA01
ATC
spironolactone; oral
14.4
24.5
42
35
TPX10
NOMESCO Finland
Implantation of vascular injection port
22.7
24.3
35
18
N18.8
ICD-10 Finland
Other chronic renal failure
27.2
24.3
33
14
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
10.0
24.0
50
62
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
38.0
24.0
30
9
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
6.3
23.8
70
148
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
12.1
23.6
44
44
ZX199
NOMESCO Finland
Other rote
21.9
23.4
34
18
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
5.4
23.4
82
214
Z49.1
ICD-10 Finland
Extracorporeal dialysis
72.8
23.4
26
*
ZX121
NOMESCO Finland
Central venous catheter
29.6
23.3
31
12
XX4AW
NOMESCO Finland
NA
10.6
23.0
46
53
A02BC01
ATC
omeprazole; systemic
6.2
23.0
69
149
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
6.5
22.9
65
130
J05AB01
ATC
aciclovir; systemic
7.5
22.7
57
96
XA800
NOMESCO Finland
Neuropsychological investigation
5.8
22.6
72
167
C09CA01
ATC
losartan; oral
25.3
22.4
31
14
C09AA02
ATC
enalapril; systemic
14.4
22.3
38
31
F59
ICD-10 Finland
Unspecified behavioural syndromes associated with physiological disturbances and physical factors
14.4
22.3
38
31
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
88.9
22.1
24
*
TAB00
NOMESCO Finland
Lumbar puncture
10.7
21.8
43
48
RS220
NOMESCO Finland
NA
11.3
21.4
41
43
BC00A
NOMESCO Finland
NA
41.5
21.3
26
7
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
13.5
20.6
36
31
Z94.1
ICD-10 Finland
Heart transplant status
114.9
19.9
21
*
RS221
NOMESCO Finland
NA
9.4
19.9
42
53
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
6.4
19.8
56
110
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
25.3
19.6
27
12
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.7
19.5
77
222
EB1WA
NOMESCO Finland
NA
60.4
19.3
22
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
21.0
19.2
28
15
V03AE01
ATC
polystyrene sulfonate; oral
109.0
18.9
20
*
K02.1
ICD-10 Finland
Caries of dentine
3.8
18.9
175
1036
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
19.7
18.8
28
16
B01AA03
ATC
warfarin; systemic
14.1
18.8
32
26
WX402
NOMESCO Finland
General anaesthesia
3.9
18.8
96
352
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
4.6
18.6
75
220
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
3.5
18.4
138
686
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
29.5
18.2
24
9
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.1
18.1
84
281
201
Kela drug reimbursment
Chronic cardiac insufficiency
14.2
17.7
30
24
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
8.6
17.6
39
53
TK820
NOMESCO Finland
Peritoneal dialysis
46.0
17.6
21
5
A05AA02
ATC
ursodeoxycholic acid; oral
17.8
17.5
27
17
WX110
NOMESCO Finland
Local anesthesy
4.2
17.2
197
1330
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.8
17.2
63
166
J05AB11
ATC
valaciclovir; oral
12.2
17.1
31
29
4AA09
NOMESCO Finland
NA
68.6
17.0
19
*
H02AB02
ATC
dexamethasone; systemic
18.1
17.0
26
16
K03.28
ICD-10 Finland
Other erosion of teeth
30.2
16.8
22
8
6BA02
NOMESCO Finland
NA
22.1
16.8
24
12
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.4
16.7
68
199
XX4BW
NOMESCO Finland
NA
17.1
16.6
26
17
ZX114
NOMESCO Finland
Intramuscular
16.1
16.3
26
18
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
3.9
16.3
79
271
B03XA02
ATC
darbepoetin alfa; parenteral
64.7
16.0
18
*
SDA02
NOMESCO Finland
Parodonthologic therapy
3.3
16.0
115
535
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
4.4
15.9
65
190
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
6.2
15.7
44
84
F43.8
ICD-10 Finland
Other reactions to severe stress
17.7
15.6
24
15
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
17.7
15.6
24
15
SFA10
NOMESCO Finland
Fillning on one surface of tooth
3.2
15.5
158
929
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
19.5
15.5
23
13
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
6.6
15.4
41
73
A49.9
ICD-10 Finland
Bacterial infection, unspecified
10.3
15.2
30
33
K03.29
ICD-10 Finland
Erosion of teeth occupational
34.3
15.1
19
6
ZX131
NOMESCO Finland
Intrathecal
60.8
15.0
17
*
L03AA02
ATC
filgrastim; parenteral
60.8
15.0
17
*
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
22.9
15.0
21
10
XF600
NOMESCO Finland
Bloodpressure measurement
3.9
14.8
71
238
WW200
NOMESCO Finland
Immunization
13.9
14.8
25
20
UDC00
NOMESCO Finland
Ear microscopy
4.9
14.6
51
126
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
20.8
14.5
21
11
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.0
14.4
147
845
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
3.6
14.1
194
1362
Z01.2
ICD-10 Finland
Dental examination
3.3
14.0
182
1221
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
8.4
14.0
31
42
RK220
NOMESCO Finland
NA
16.1
13.9
22
15
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
+∞
13.7
13
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
13.7
13
*
L01BB02
ATC
mercaptopurine; oral
19.7
13.6
20
11
TFJ02
NOMESCO Finland
Muscle biopsy of heart
148.3
13.6
14
*
J01MA02
ATC
ciprofloxacin; systemic
5.2
13.6
44
100
K07.24
ICD-10 Finland
Open bite
6.6
13.4
35
61
IGY02
NOMESCO Finland
Psychiatric monitoring contact
4.5
13.3
51
138
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
8.9
13.3
28
35
J02AC01
ATC
fluconazole; systemic
4.7
13.2
48
123
B07.9
ICD-10 Finland
Verruca simplex
6.5
13.2
35
62
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
53.2
13.0
15
*
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
7.5
12.7
30
45
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.8
12.7
127
701
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
26.0
12.7
17
7
WX002
NOMESCO Finland
Sedation and analgesia
4.4
12.5
48
130
RK110
NOMESCO Finland
NA
13.5
12.4
21
17
C10AA03
ATC
pravastatin; oral
39.9
12.4
15
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
11.0
12.3
23
23
JAH00
NOMESCO Finland
Laparotomy
19.4
12.3
18
10
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
19.4
12.3
18
10
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
19.4
12.3
18
10
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
3.1
12.2
84
361
B34.9
ICD-10 Finland
Viral infection, unspecified
4.2
12.2
49
138
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
9.8
12.1
24
27
WX302
NOMESCO Finland
Thoracal epidural anesthesy
15.8
12.0
19
13
C08CA05
ATC
nifedipine; systemic
49.4
12.0
14
*
A01AB09
ATC
miconazole; local oral
6.7
11.8
30
50
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
68.5
11.7
13
*
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.9
11.5
51
157
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
8.4
11.5
25
33
1AB02
NOMESCO Finland
NA
18.2
11.4
17
10
SFA40
NOMESCO Finland
Replacement of krone of tooth
7.3
11.4
27
41
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.9
11.2
82
365
XF622
NOMESCO Finland
Measurement of minute volume of heart
12.8
11.1
19
16
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.8
11.0
49
151
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
45.6
11.0
13
*
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
8.7
10.9
23
29
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
22.8
10.8
15
7
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
5.7
10.8
31
61
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
63.0
10.7
12
*
K65.0
ICD-10 Finland
Acute peritonitis
63.0
10.7
12
*
WZB00
NOMESCO Finland
Telephone receipt or other advice
3.2
10.7
65
253
RS121
NOMESCO Finland
NA
8.9
10.6
22
27
JJC00
NOMESCO Finland
Allogenic transplantation of liver
+∞
10.5
10
*
YNB20
NOMESCO Finland
Storage of stem cells for transplant
+∞
10.5
10
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
8.1
10.5
23
31
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
34.3
10.4
13
*
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
34.3
10.4
13
*
RL140
NOMESCO Finland
NA
6.1
10.4
28
51
SCF02
NOMESCO Finland
Preventive oral care by dental hygienist
3.9
10.3
45
136
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.1
10.3
64
255
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
12.1
10.2
18
16
R4190
NOMESCO Finland
Nutritional therapy
3.0
10.2
67
277
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
7.6
10.1
23
33
RT150
NOMESCO Finland
NA
6.7
10.0
25
41
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
5.6
10.0
29
58
Z31.5
ICD-10 Finland
Genetic counselling
3.9
10.0
43
129
KAS20
NOMESCO Finland
Allogenic transplantation of kidney from living donor
27.4
9.9
13
5
WX892
NOMESCO Finland
Monitored bed care
4.1
9.9
39
108
GD1AD
NOMESCO Finland
Thorax CT examination
14.2
9.8
16
12
WX1PA
NOMESCO Finland
Total body mineral density measurement with Dual energy X-ray absorptiometry (DXA)
14.2
9.8
16
12
A06AD11
ATC
lactulose; oral
5.9
9.7
27
51
1XC02
NOMESCO Finland
NA
57.5
9.7
11
*
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
7.2
9.7
23
35
TJD20
NOMESCO Finland
Change of gastrostomy tube
10.7
9.7
18
18
A02BC05
ATC
esomeprazole; systemic
4.1
9.7
39
110
R62.0
ICD-10 Finland
Delayed milestone
3.7
9.7
44
138
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.0
9.6
40
116
XF404
NOMESCO Finland
Ambulatory ECG
4.3
9.6
36
95
SAB02
NOMESCO Finland
Oral and dental health check by dental hygienist or dental assistant
0.4
9.5
46
934
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
13.1
9.5
16
13
130
Kela drug reimbursment
Malignant tumour
13.1
9.5
16
13
J01FF01
ATC
clindamycin; systemic
4.2
9.5
37
101
WX704
NOMESCO Finland
Intubation
5.4
9.5
28
57
WW409
NOMESCO Finland
Other aferesis
31.5
9.5
12
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
31.5
9.5
12
*
61
HP
Catheterization and pressure measurement of the left side of the heart
104.1
9.5
10
*
3A013
NOMESCO Finland
NA
104.1
9.5
10
*
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
104.1
9.5
10
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.5
9.5
34
86
H52.0
ICD-10 Finland
Hypermetropia
4.6
9.5
33
81
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
2.4
9.4
131
816
783
NOMESCO Finland
NA
+∞
9.4
9
*
N19
ICD-10 Finland
Unspecified kidney failure
+∞
9.4
9
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.0
9.4
62
254
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
5.0
9.4
30
67
A04AA01
ATC
ondansetron; systemic, rectal
5.3
9.4
28
58
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
6.8
9.4
23
37
TQW99
NOMESCO Finland
Other minor procedure on skin
8.3
9.4
20
26
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.5
9.3
46
154
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
14.5
9.3
15
11
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.6
9.3
21
30
B01.9
ICD-10 Finland
Varicella without complication
6.0
9.2
25
46
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
9.7
9.2
18
20
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
6.6
9.2
23
38
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
16.4
9.2
14
9
KAB00
NOMESCO Finland
Biopsy of kidney or pelvis of kidney
38.3
9.1
11
*
N04.0
ICD-10 Finland
Nephrotic syndrome, minor glomerular abnormality
19.6
9.0
13
7
RK230
NOMESCO Finland
NA
11.4
8.9
16
15
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
3.0
8.9
57
229
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
2.3
8.9
135
867
K00.68
ICD-10 Finland
Other disturbance in the tooth eruption
4.4
8.8
32
82
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
12.2
8.7
15
13
UJF32
NOMESCO Finland
Coloscopy
4.4
8.7
31
78
I15.8
ICD-10 Finland
Other secondary hypertension
17.1
8.7
13
8
QXB05
NOMESCO Finland
Skin wound assessment, unspecified location
13.4
8.5
14
11
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
93.3
8.5
9
*
FQA00
NOMESCO Finland
Orthotopic transplantation of heart
93.3
8.5
9
*
L04AA05
ATC
[U] tacrolimus; systemic
93.3
8.5
9
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.3
8.5
119
732
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.6
8.4
24
47
Q44.20
ICD-10 Finland
Atresia of intrahepatic bile ducts
+∞
8.4
8
*
ZX196
NOMESCO Finland
NA
+∞
8.4
8
*
AA1AD
NOMESCO Finland
CT of head and brain
4.5
8.4
29
71
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
8.0
8.3
18
24
RK320
NOMESCO Finland
NA
15.2
8.3
13
9
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
7.3
8.3
19
28
KA1AE
NOMESCO Finland
Kidney ultrasound examination
8.6
8.2
17
21
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
18.0
8.2
12
7
ZX197
NOMESCO Finland
NA
34.7
8.1
10
*
324
NOMESCO Finland
NA
34.7
8.1
10
*
3A077
NOMESCO Finland
NA
34.7
8.1
10
*
N18.0
ICD-10 Finland
End-stage renal disease
34.7
8.1
10
*
R5120
NOMESCO Finland
Preparation of an aid
34.7
8.1
10
*
1XX02
NOMESCO Finland
NA
34.7
8.1
10
*
TJW99
NOMESCO Finland
Other minor procedure in gastrointestinal endoscopy
23.0
8.1
11
5
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
4.1
8.1
31
84
A08.0
ICD-10 Finland
Rotaviral enteritis
6.5
8.0
20
33
UKC02
NOMESCO Finland
Cystoscopy
6.5
8.0
20
33
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.4
8.0
40
135
P85
ICPC
Mental retardation
7.4
7.9
18
26
JAB00
NOMESCO Finland
Division and ligature of inguinal hernia sac
6.0
7.9
21
38
TK823
NOMESCO Finland
Peritoneal permeability analysis
46.6
7.8
9
*
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
46.6
7.8
9
*
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
46.6
7.8
9
*
Q44.21
ICD-10 Finland
Atresia of extrahepatic bile ducts
46.6
7.8
9
*
G62.0
ICD-10 Finland
Drug-induced polyneuropathy
46.6
7.8
9
*
J01MA12
ATC
levofloxacin; systemic
8.5
7.7
16
20
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
19.2
7.7
11
6
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.9
7.7
31
88
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
7.5
58
260
H52.2
ICD-10 Finland
Astigmatism
4.6
7.5
25
59
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.2
7.5
28
74
B02.9
ICD-10 Finland
Zoster without complication
14.0
7.5
12
9
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
14.0
7.5
12
9
RK260
NOMESCO Finland
NA
14.0
7.5
12
9
RS210
NOMESCO Finland
NA
14.0
7.5
12
9
JKD50
NOMESCO Finland
Hepatoportoenterostomy
82.6
7.5
8
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
82.6
7.5
8
*
K06.10
ICD-10 Finland
Gingival fibromatosis
82.6
7.5
8
*
WW400
NOMESCO Finland
Plasmaferesis
82.6
7.5
8
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
82.6
7.5
8
*
TK810
NOMESCO Finland
Hemofiltration
82.6
7.5
8
*
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
2.9
7.4
49
199
SCF03
NOMESCO Finland
Preventive oral care by dental hygienist, extensive
7.2
7.4
17
25
J01EA01
ATC
trimethoprim; systemic
3.4
7.4
36
119
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.7
7.4
24
55
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
11.4
7.4
13
12
TJF80
NOMESCO Finland
Ostomy education
9.8
7.4
14
15
H66.9
ICD-10 Finland
Otitis media, unspecified
2.2
7.4
97
566
2AX05
NOMESCO Finland
NA
+∞
7.3
7
*
JJC10
NOMESCO Finland
Allogenic partial transplantation of liver
+∞
7.3
7
*
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
7.0
7.3
17
26
RS222
NOMESCO Finland
NA
5.1
7.2
22
47
Z85.6
ICD-10 Finland
Personal history of leukaemia
31.1
7.2
9
*
K05.11
ICD-10 Finland
Gingivitis (chronic) hyperplastic
31.1
7.2
9
*
31
HP
Congenital heart failure surgery
31.1
7.2
9
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
9.2
7.2
14
16
R11
ICD-10 Finland
Nausea and vomiting
3.0
7.1
43
164
Z01.9
ICD-10 Finland
Special examination, unspecified
6.7
7.1
17
27
A28
ICPC
Limited function/disability NOS
3.5
7.1
33
106
XX8XW
NOMESCO Finland
NA
14.4
7.0
11
8
NE1AA
NOMESCO Finland
Pelvis X-ray examination
6.5
6.9
17
28
JAF10
NOMESCO Finland
Repair of umbilical hernia
11.4
6.9
12
11
J20.5
ICD-10 Finland
Acute bronchitis due to respiratory syncytial virus
17.3
6.8
10
6
9811/3-C42.1
ICD-O-3
B lymphoblastic leukemia/lymphoma, NOS, of bone marrow
41.3
6.8
8
*
K03.21
ICD-10 Finland
Erosion of teeth due to: persistent vomiting
41.3
6.8
8
*
Z49.0
ICD-10 Finland
Preparatory care for dialysis
41.3
6.8
8
*
H26.3
ICD-10 Finland
Drug-induced cataract
41.3
6.8
8
*
R1260
NOMESCO Finland
Evaluation of communicative skills
6.8
6.8
16
25
RK224
NOMESCO Finland
NA
23.3
6.7
9
*
Q44.29
ICD-10 Finland
Atresia of bile ducts
23.3
6.7
9
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
8.2
6.7
14
18
XKD00
NOMESCO Finland
Uroflowmetry
3.8
6.7
27
77
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.4
6.7
62
305
K00.50
ICD-10 Finland
Dentinal dysplasia
10.5
6.6
12
12
TQW80
NOMESCO Finland
Local dermatologic skincare
10.5
6.6
12
12
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
10.5
6.6
12
12
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
6.5
6.6
16
26
F83
ICD-10 Finland
Mixed specific developmental disorders
3.6
6.6
29
89
ZX112
NOMESCO Finland
Subcutaneous
7.8
6.5
14
19
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.3
6.5
23
58
N02AX02
ATC
tramadol; systemic, rectal
3.4
6.5
30
96
IEP02
NOMESCO Finland
Child-centred family therapy
3.8
6.5
26
74
B05XA03
ATC
sodium chloride; parenteral
71.7
6.5
7
*
YNB00
NOMESCO Finland
Excision of bone marrow for transplantation
71.7
6.5
7
*
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
14.8
6.5
10
7
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
6.9
6.4
15
23
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
9.7
6.4
12
13
ZX100
NOMESCO Finland
Oral
11.5
6.4
11
10
RT160
NOMESCO Finland
NA
5.3
6.3
18
36
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
+∞
6.3
6
*
T86.1
ICD-10 Finland
Kidney transplant failure and rejection
+∞
6.3
6
*
E42
ICD-10 Finland
Marasmic kwashiorkor
+∞
6.3
6
*
JJC50
NOMESCO Finland
Resection of transplanted liver
+∞
6.3
6
*
C01AA05
ATC
digoxin; systemic
+∞
6.3
6
*
FAE10
NOMESCO Finland
Bidirectional anastomosis between superior vena cava and pulmonary artery
27.5
6.3
8
*
TBW99
NOMESCO Finland
Other minor procedure in endocrine surgery
3.4
6.3
29
93
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.2
6.3
79
445
L28
ICPC
Limited function/disability (L)
3.8
6.2
25
71
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
3.3
6.2
30
99
G04BE03
ATC
sildenafil; oral
8.0
6.2
13
17
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
9.0
6.1
12
14
NF1DA
NOMESCO Finland
X-ray of hips
9.0
6.1
12
14
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.9
6.1
24
67
TDM10
NOMESCO Finland
Puncture of maxillary antrum
6.3
6.1
15
25
WX306
NOMESCO Finland
Lumbar epidural anesthesy
6.3
6.1
15
25
K03.22
ICD-10 Finland
Erosion of teeth due to: diet
10.4
6.1
11
11
H53.0
ICD-10 Finland
Amblyopia ex anopsia
4.3
6.1
21
52
H01AC01
ATC
somatropin; parenteral
3.4
6.0
28
90
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
7.6
6.0
13
18

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
63
18
45.38
102.46
40.3
39.0
128.8
137.9
ug/l
0.15
57
18
122
148
14.32
101.76
12.6
4.5
316.5
281.0
umol/l
1.84
122
140
94
88
15.91
92.18
4.1
3.0
13.4
33.5
mu/l
1.39
94
80
151
278
11.20
90.19
8.3
2.5
13.4
14.6
umol/l
1.25
151
272
80
67
16.58
83.35
2.7
1.5
—
—
—
0
0
127
209
10.67
82.33
6.3
3.3
59.9
61.7
e9/l
0.19
106
121
88
96
13.15
77.35
4.2
1.6
72.1
80.2
u/ml
—
6
5
88
97
13.01
76.78
4.1
1.6
—
—
—
0
0
97
133
10.86
71.87
10.3
8.2
0.2
0.3
g/l
0.61
89
106
179
551
7.84
61.26
28.9
6.1
—
—
—
0
0
113
224
8.00
60.06
20.8
3.9
6.1
6.4
umol/l
0.07
101
177
92
155
8.51
56.41
4.0
1.5
210.8
155.9
u/ml
0.72
62
57
43
23
22.02
55.34
3.3
1.7
—
—
—
0
0
156
465
6.66
53.66
9.9
3.1
610.0
617.3
mosm/kgh2o
0.14
149
392
179
626
6.65
50.90
30.1
5.3
1.2
1.2
mmol/l
0.01
163
495
179
628
6.62
50.65
30.2
5.3
5.7
5.9
kpa
1.43
179
611
176
609
6.55
50.56
28.4
5.1
5.4
5.1
kpa
1.27
176
595
136
377
6.31
50.03
16.4
3.3
7.4
7.4
ph
2.06
30
41
151
468
6.12
48.77
12.5
3.0
4.1
5.4
e6/l
1.21
146
402
44
33
15.72
47.75
4.4
4.4
20.3
22.1
umol/l
0.90
44
33
209
878
7.40
47.20
27.6
6.4
—
—
—
0
0
110
264
6.37
46.92
11.4
3.5
—
—
—
0
0
141
424
5.92
46.77
7.3
2.2
—
—
—
0
0
151
487
5.83
46.03
8.3
2.3
—
—
—
0
0
39
27
16.69
44.08
1.9
1.6
—
—
—
0
0
102
259
5.74
40.16
9.7
3.1
3.3
2.4
mg/l
0.22
88
177
114
319
5.48
40.13
2.0
1.7
1.2
1.2
mmol/l
0.23
114
299
226
1112
7.81
39.94
30.0
6.7
—
—
—
0
0
50
60
9.99
39.77
6.6
2.7
—
—
—
0
0
52
66
9.51
39.61
6.3
2.6
67.9
70.3
%
0.27
52
66
172
679
5.31
39.52
14.9
3.8
0.1
0.2
e6/l
0.20
153
512
83
178
6.30
39.19
3.2
2.4
8.0
8.1
iu/l
0.01
57
103
88
201
6.02
38.82
3.3
2.4
4.8
4.6
u/l
0.07
62
113
52
68
9.23
38.66
6.3
2.6
1.1
1.6
e9/l
1.84
41
52
135
447
5.08
38.48
8.2
3.5
1.9
1.7
e6/l
0.16
109
274
171
683
5.18
38.41
14.8
3.7
—
—
—
0
0
45
49
10.81
38.38
3.3
1.6
—
—
—
0
0
45
49
10.81
38.38
3.3
1.6
—
—
—
0
0
45
49
10.81
38.38
3.3
1.6
—
—
—
0
0
45
49
10.81
38.38
3.3
1.6
—
—
—
0
0
32
20
17.98
37.93
16.8
4.1
—
—
—
0
0
161
635
4.87
36.17
8.3
3.3
—
—
—
0
0
41
43
11.05
35.82
2.8
1.4
—
—
—
0
0
154
592
4.78
35.65
25.2
6.0
7.4
7.4
ph
—
21
10
173
730
4.89
35.33
16.7
3.9
11.7
21.1
e6/l
1.33
157
557
53
79
8.10
35.22
5.5
3.4
—
—
—
0
0
117
372
4.81
34.46
11.4
3.7
1.1
1.2
inr
0.39
23
75
57
97
7.18
33.55
7.8
5.1
0.4
0.4
%
0.02
29
35
31
23
15.07
33.51
3.2
2.8
—
—
—
0
0
31
23
15.07
33.51
1.6
1.4
—
—
—
0
0
184
837
4.86
33.42
19.6
4.6
14.3
43.9
e6/l
2.36
156
569
102
297
4.93
33.42
4.0
1.5
—
—
—
0
0
62
116
6.64
33.29
2.3
1.6
—
—
—
0
0
47
65
8.53
33.20
6.2
2.9
192.8
411.0
e6/l
2.73
36
50
53
86
7.42
32.56
7.0
4.8
0.3
0.4
%
0.13
24
25
139
523
4.45
32.41
25.6
5.8
—
—
—
0
0
64
128
6.24
32.06
3.4
1.9
—
—
—
0
0
53
91
7.00
30.82
7.7
5.2
0.0
0.0
%
0.00
25
28
23
11
22.71
30.50
1.0
1.0
—
—
—
0
0
23
11
22.71
30.50
1.0
1.3
—
—
—
0
0
131
490
4.28
30.40
7.5
2.9
—
—
—
0
0
238
1386
7.75
30.23
35.6
7.0
0.0
0.0
e9/l
1.84
223
1118
238
1388
7.73
30.12
35.6
7.0
0.6
0.6
e9/l
1.50
223
1121
209
1103
5.14
29.79
23.9
5.1
5.6
6.3
mmol/l
10.43
204
1045
70
163
5.45
29.60
2.8
1.7
—
—
—
0
0
44
66
7.76
28.87
6.4
2.6
453.3
573.8
e6/l
0.69
34
53
43
63
7.92
28.79
6.6
2.7
26.1
25.0
%
0.22
43
63
238
1413
7.44
28.77
40.4
7.5
0.2
0.2
e9/l
0.65
226
1177
35
40
9.89
28.57
6.4
3.9
—
—
—
0
0
44
67
7.64
28.48
6.4
2.6
0.1
0.2
e9/l
2.18
34
54
37
46
9.15
28.33
16.1
5.2
—
—
—
0
0
238
1426
7.30
28.08
35.5
7.0
2.2
2.3
e9/l
0.94
227
1193
35
41
9.64
28.04
2.9
1.4
—
—
—
0
0
36
44
9.27
27.92
15.1
2.5
—
—
—
0
0
33
36
10.28
27.85
6.5
3.7
3.2
2.8
e9/l
0.58
33
36
33
36
10.28
27.85
6.5
4.0
—
—
—
0
0
33
8
46.68
27.44
4.1
2.8
—
—
—
0
0
227
1335
5.73
26.63
39.0
7.9
0.0
0.0
e9/l
0.97
207
987
33
39
9.48
26.22
8.4
3.6
48.8
49.1
%
0.04
33
39
49
92
6.28
25.92
8.4
5.3
0.0
0.0
%
0.03
28
31
237
1468
6.58
25.38
43.1
7.8
3.1
3.4
e9/l
0.87
223
1193
142
622
3.73
25.08
10.5
2.8
—
—
—
0
0
36
55
7.38
23.09
20.7
7.5
1.2
1.2
mmol/l
0.40
36
45
80
250
4.13
22.94
3.5
1.6
—
—
—
0
0
48
99
5.67
22.91
12.4
3.5
219.3
158.1
ng/l
0.38
48
93
128
553
3.52
22.55
3.8
3.8
2.9
2.5
mg/l
1.43
118
492
26
28
10.14
22.01
17.8
9.0
0.8
2.0
mmol/l
1.38
13
15
26
28
10.14
22.01
17.8
9.0
10.8
8.3
kpa
3.68
26
28
26
28
10.14
22.01
17.8
9.0
4.8
4.9
kpa
0.29
26
28
97
363
3.62
21.20
6.2
2.4
—
—
—
0
0
22
20
11.86
20.84
4.5
1.9
78.0
66.3
mg/l
0.34
22
20
29
42
7.60
19.41
7.6
2.7
—
—
—
0
0
57
157
4.33
19.13
3.1
2.2
9.8
7.9
nmol/l
0.74
46
114
199
1201
3.58
19.10
17.4
3.7
—
—
—
0
0
17
12
15.01
18.57
3.3
2.2
—
—
—
0
0
152
794
3.12
18.48
12.7
3.0
0.0
0.0
estimate
0.00
35
109
188
1111
3.34
18.37
16.2
3.3
83.8
30.3
e6/l
—
10
9
29
45
7.08
18.23
31.2
10.0
—
—
—
0
0
28
42
7.31
18.14
31.8
13.0
72.4
74.5
%
0.23
28
42
148
787
2.97
17.00
13.0
3.0
0.0
0.0
estimate
0.00
32
102
148
788
2.96
16.94
18.0
4.4
0.0
0.0
estimate
0.00
35
112
21
24
9.38
16.93
2.1
1.7
—
—
—
0
0
85
336
3.23
16.48
2.2
1.6
—
—
—
0
0
16
13
12.98
16.10
2.2
1.6
—
—
—
0
0
67
235
3.46
15.70
2.6
1.5
—
—
—
0
0
24
36
7.20
15.50
6.1
4.5
2.8
5.2
u/ml
0.50
24
36
14
0
+∞
14.70
3.3
0.0
—
—
—
0
0
18
21
9.09
14.23
1.5
1.5
—
—
—
0
0
22
33
7.15
14.18
2.1
2.9
15.9
15.2
umol/l
0.08
22
33
62
220
3.36
14.16
6.3
2.7
856.6
1595.1
ng/l
0.59
42
134
17
21
8.55
12.84
1.0
1.4
—
—
—
0
0
77
331
2.85
12.49
2.4
1.6
—
—
—
0
0
78
341
2.81
12.23
20.2
4.6
—
—
—
0
0
18
26
7.33
11.95
41.2
15.1
11.0
12.3
%
0.90
18
26
15
18
8.74
11.55
1.7
1.4
—
—
—
0
0
65
265
2.91
11.54
2.5
1.6
196.9
750.7
titre
2.18
13
43
15
19
8.28
11.07
1.0
1.5
—
—
—
0
0
74
332
2.69
10.90
2.1
1.5
101.4
97.6
pmol/l
0.34
36
160
15
7
22.51
10.78
2.7
1.6
32.3
32.9
pg
—
15
7
37
112
3.66
10.66
1.3
1.1
—
—
—
0
0
15
20
7.86
10.62
1.4
1.2
—
—
—
0
0
18
30
6.34
10.48
1.1
1.4
—
—
—
0
0
28
72
4.21
10.08
1.8
1.2
—
—
—
0
0
26
64
4.38
9.89
10.5
4.0
—
—
—
0
0
40
134
3.32
9.85
2.0
1.3
—
—
—
0
0
32
94
3.72
9.61
23.0
9.2
-0.6
-0.7
mmol/l
0.04
26
74
14
9
16.26
9.11
6.1
4.3
193.9
231.8
ug/l
—
14
9
27
73
3.99
9.09
26.4
10.9
23.6
23.5
mmol/l
0.06
27
73
13
7
19.36
9.00
13.2
4.9
—
—
—
0
0
84
435
2.35
8.92
2.5
2.1
—
—
—
0
0
257
2240
5.22
8.92
68.4
11.3
36.7
39.4
%
14.16
249
2052
25
67
4.00
8.51
1.3
1.2
—
—
—
0
0
19
42
4.78
8.21
1.5
3.1
27.4
43.5
mmol/l
1.62
19
42
12
17
7.32
8.02
1.9
3.4
1.1
1.1
umol/l
0.04
12
17
247
2057
3.75
8.02
30.9
6.4
—
—
—
0
0
19
43
4.66
7.99
17.1
6.9
—
—
—
0
0
31
102
3.30
7.83
15.5
2.7
—
—
—
0
0
156
1074
2.08
7.77
4.2
2.1
5.3
5.4
mmol/l
1.62
150
962
10
5
20.61
7.17
15.7
22.4
—
—
—
0
0
10
5
20.61
7.17
1.6
1.0
5.9
—
pmol/l
—
5
0
10
13
7.92
7.13
1.3
1.0
—
—
—
0
0
10
13
7.92
7.13
1.3
1.0
—
—
—
0
0
10
13
7.92
7.13
1.3
1.0
—
—
—
0
0
47
206
2.55
7.06
5.8
4.0
234.9
148.7
mg/l
0.42
41
168
45
194
2.58
6.99
4.2
2.1
74.1
31.1
ng/l
0.45
29
65
22
62
3.76
6.99
1.4
1.5
1357.1
1113.2
nmol/l
0.53
17
47
18
45
4.20
6.70
8.1
2.6
—
—
—
0
0
10
8
12.88
6.12
1.9
2.6
—
—
—
0
0
22
68
3.42
6.11
5.4
1.8
40.6
30.1
umol/l
1.64
22
60
19
54
3.70
5.96
35.3
11.8
—
—
—
0
0
21
65
3.41
5.82
34.3
12.3
0.7
0.7
%
0.32
21
65
21
66
3.36
5.69
34.3
12.2
93.5
95.6
%
0.57
21
66
94
591
1.90
5.60
1.8
1.5
—
—
—
0
0
64
353
2.06
5.54
18.0
3.2
0.0
0.0
estimate
0.00
33
110
27
102
2.82
5.39
2.0
1.4
0.2
0.2
g/l
0.15
27
97
245
2131
2.84
5.37
52.5
8.2
19.6
24.8
mg/l
2.63
215
1327
19
59
3.38
5.25
3.1
2.4
—
—
—
0
0
27
104
2.77
5.20
2.0
1.4
1.0
1.2
g/l
1.26
27
98
22
76
3.05
5.13
13.0
2.7
—
—
—
0
0
8
6
13.64
5.10
4.3
1.8
47.2
39.9
%
—
8
6
20
66
3.18
5.03
35.1
12.2
1.0
1.0
%
0.18
20
66
17
51
3.48
4.94
3.3
1.6
10.1
6.6
ug/l
0.33
11
39
35
158
2.39
4.91
4.7
2.9
—
—
—
0
0
12
28
4.42
4.85
10.7
5.2
31.8
21.7
ug/l
0.62
12
28
31
133
2.50
4.84
2.1
1.4
—
—
—
0
0
10
20
5.14
4.79
2.9
3.0
—
—
—
0
0
31
134
2.48
4.77
1.7
1.5
—
—
—
0
0
23
88
2.76
4.50
1.5
1.5
—
—
—
0
0
139
1039
1.70
4.33
2.7
1.7
1.5
1.5
g/l
0.21
96
440
58
337
1.91
4.26
15.9
2.6
—
—
—
0
0
43
228
2.05
4.09
3.3
1.6
—
—
—
0
0
8
10
8.17
4.08
1.1
1.2
—
—
—
0
0
21
81
2.72
4.05
13.9
2.7
653.6
323.7
mg/l
0.36
21
81
7
7
10.19
4.02
1.9
1.1
—
—
—
0
0
19
70
2.84
3.98
15.1
2.8
—
—
—
0
0
12
33
3.75
3.94
1.4
1.3
2.6
4.0
u/ml
—
7
21
8
11
7.43
3.87
1.1
1.1
—
—
—
0
0
9
16
5.76
3.68
2.0
1.3
—
—
—
0
0
15
53
2.93
3.39
1.6
1.2
—
—
—
0
0
7
10
7.13
3.37
2.1
1.4
—
—
—
0
0
7
11
6.48
3.19
1.9
2.2
1405.7
1698.0
u/ml
—
7
11
15
56
2.77
3.09
4.4
2.0
—
—
—
0
0
6
8
7.61
3.06
1.2
1.6
9.9
28.1
u/l
—
6
8
13
45
2.97
3.05
1.5
1.1
—
—
—
0
0
5
5
10.12
2.98
1.4
2.8
107.2
106.4
mmol/l
—
5
5
5
5
10.12
2.98
6.4
24.8
13.7
13.3
ml/dl
—
5
5
5
5
10.12
2.98
1.4
2.8
—
—
—
0
0
9
22
4.18
2.90
1.1
1.1
—
—
—
0
0
5
6
8.43
2.75
1.4
2.5
4.6
3.9
mmol/l
—
5
6
99
742
1.52
2.70
4.0
2.1
—
—
—
0
0
6
10
6.09
2.70
1.5
1.7
15.9
17.1
umol/l
—
6
10
14
56
2.57
2.55
1.4
1.4
367.0
374.3
ug/g
—
7
32
56
377
1.61
2.42
13.1
2.7
1.0
1.0
kg/l
—
7
70
15
64
2.41
2.41
1.7
1.1
—
—
—
0
0
8
22
3.70
2.37
2.3
2.3
—
—
—
0
0
7
18
3.95
2.26
4.1
1.9
—
—
—
0
0
7
18
3.95
2.26
6.4
3.4
1.9
1.4
mmol/l
—
7
18
6
14
4.34
2.15
1.2
1.2
71.7
74.5
%
—
6
14
6
14
4.34
2.15
1.2
1.2
384.5
380.0
mu/l
—
6
14
12
51
2.41
1.96
15.3
4.7
—
—
—
0
0
5
11
4.59
1.94
1.2
1.1
—
—
—
0
0
5
11
4.59
1.94
1.2
1.1
—
—
—
0
0
7
22
3.23
1.88
1.1
1.0
—
—
—
0
0
195
1740
1.44
1.84
4.5
3.7
2.1
2.0
mu/l
0.83
190
1631
9
35
2.62
1.81
1.3
1.1
—
—
—
0
0
7
23
3.09
1.80
1.0
1.0
—
—
—
0
0
8
31
2.62
1.66
1.1
1.0
1.6
1.4
g/l
—
8
31
22
133
1.71
1.46
4.2
1.7
2.4
2.4
mmol/l
0.28
22
100
7
29
2.44
1.39
1.6
2.1
55.9
30.1
u/ml
—
7
29
7
29
2.44
1.39
1.6
1.3
—
—
—
0
0
12
62
1.97
1.28
2.1
1.6
—
—
—
0
0
8
36
2.25
1.25
1.3
1.2
—
—
—
0
0
18
109
1.69
1.21
4.4
2.1
4.3
4.3
e9/l
0.02
18
103
37
267
1.44
1.19
1.7
1.8
—
—
—
0
0
6
26
2.33
1.18
1.2
1.0
—
—
—
0
0
14
80
1.78
1.14
1.4
1.1
—
—
—
0
0
84
699
1.29
1.10
2.2
1.9
—
—
—
0
0
14
81
1.76
1.10
1.3
1.1
—
—
—
0
0
27
190
1.46
1.00
1.4
1.2
11.1
24.1
iu/ml
—
7
37
7
37
1.91
0.94
3.4
2.5
1.1
1.8
nmol/l
—
7
32
6
27
2.24
0.94
5.5
2.8
16.0
22.8
mg/l
—
6
16
13
78
1.69
0.92
4.9
6.2
1.6
2.0
ug/l
0.45
13
78
6
32
1.89
0.82
1.0
1.3
—
33.4
—
0
9
7
39
1.81
0.73
1.1
1.6
—
—
—
0
0
7
39
1.81
0.73
1.1
1.6
—
—
—
0
0
7
40
1.76
0.71
1.3
1.7
—
—
—
0
0
7
40
1.76
0.71
2.3
1.8
—
—
—
0
0
5
26
1.93
0.71
1.0
1.2
—
—
—
0
0
13
86
1.53
0.66
1.2
1.3
0.6
12.2
u/ml
—
8
73
5
29
1.73
0.64
1.6
1.0
—
—
—
0
0
20
147
1.38
0.62
4.0
2.6
7865.5
3629.1
u/l
—
6
44
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
18
131
1.40
0.60
1.3
1.1
—
—
—
0
0
13
91
1.44
0.53
1.5
1.2
—
—
—
0
0
5
82
0.60
0.46
1.0
1.3
—
—
—
0
0
8
55
1.46
0.43
1.0
1.3
—
—
—
0
0
5
32
1.57
0.42
2.2
2.2
0.8
1.0
ug/l
—
5
27
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
0.5
—
0
15
5
36
1.39
0.38
1.4
1.1
—
—
—
0
0
8
114
0.69
0.38
1.0
1.1
—
—
—
0
0
45
394
1.17
0.37
1.3
1.5
—
294.8
—
0
21
19
152
1.26
0.37
2.0
1.5
—
—
—
0
0
11
82
1.35
0.34
1.8
1.9
—
—
—
0
0
7
97
0.71
0.31
1.3
1.2
—
—
—
0
0
107
1127
0.91
0.29
1.6
2.1
0.9
5.4
u/ml
—
10
164
19
225
0.83
0.28
1.7
2.0
—
—
—
0
0
19
223
0.84
0.26
1.7
2.0
—
—
—
0
0
19
223
0.84
0.26
1.7
2.0
—
—
—
0
0
12
95
1.27
0.26
1.3
1.1
—
—
—
0
0
18
211
0.84
0.25
1.7
2.0
—
—
—
0
0
19
220
0.85
0.23
1.7
2.0
—
—
—
0
0
5
39
1.28
0.23
4.0
1.6
—
—
—
0
0
7
93
0.74
0.23
1.0
1.2
—
—
—
0
0
22
251
0.86
0.22
1.0
1.2
0.5
4.5
u/ml
—
5
86
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
6
47
1.28
0.20
1.0
1.0
—
—
—
0
0
6
47
1.28
0.20
1.0
1.0
20.8
18.8
mmol/l
—
6
47
0
14
0.00
0.20
0.0
2.9
—
1.4
—
0
9
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
10
80
1.25
0.20
3.4
1.8
—
—
—
0
0
13
116
1.12
0.09
2.0
1.6
—
—
—
0
0
17
155
1.10
0.08
2.2
2.4
—
—
—
0
0
52
537
0.96
0.07
1.2
1.3
—
—
—
0
0
38
365
1.04
0.05
1.1
1.2
—
60.8
—
0
6
28
270
1.04
0.02
1.5
1.3
0.7
3.2
u/ml
2.12
20
189
13
123
1.06
0.01
1.7
2.3
—
—
—
0
0
11
111
0.99
0.00
1.1
1.2
—
—
—
0
0
26
256
1.01
0.00
1.2
1.3
0.1
1.4
u/ml
2.60
20
196
26
260
1.00
0.00
1.2
1.2
0.5
7.2
u/ml
8.46
20
206
18
181
0.99
0.00
1.6
2.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
0.3
—
0
5
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
3.9
—
0.4
—
0
8
5
51
0.98
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint K11_MIH_CARIES and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_MIH_CARIES.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: K11_MIH_CARIES – Molar incisor enamel hypoplasia, with caries

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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