cerebral palsy: A group of disorders affecting the development of movement and posture, often accompanied by disturbances of sensation, perception, cognition, and behavior. It results from damage to the fetal or infant brain.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
664 |
4. Check minimum number of eventsNone |
664 |
5. Include endpointsNone |
664 |
6. Filter based on genotype QC (FinnGen only) |
628 |
Control definitions (FinnGen only)
- Control exclude
- G6_CPETAL
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G80-G83
- Name in latin
- Paralysis cerebralis infantilis
Similar endpoints
↥List of similar endpoints to
Cerebral palsy
based on the number of shared cases.
Similar with more cases:
- Cerebral palsy and other paralytic syndromes
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 13423 | 5771 | 7608 |
| Only index persons | 10731 | 4719 | 6012 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.19 | 0.17 | 0.21 |
| Only index persons | 0.20 | 0.17 | 0.23 |
| Median age at first event (years) | |||
| Whole population | 4.66 | 4.71 | 4.29 |
| Only index persons | 4.37 | 4.68 | 4.12 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 628 | 332 | 296 |
| Unadjusted period prevalence (%) | 0.13 | 0.12 | 0.14 |
| Median age at first event (years) | 5.43 | 5.90 | 4.91 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 664
- Matched controls
- 6640
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
+∞
204.0
185
*
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
+∞
188.8
172
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
14.6
179.2
183
169
M03BX01
ATC
baclofen; systemic
31.3
160.4
108
41
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
+∞
152.1
140
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
15.9
131.5
121
92
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
+∞
116.1
108
*
SPAT1229
SPAT
Assessment of need for aid
14.1
111.6
109
91
N05BA09
ATC
clobazam; oral
23.6
92.3
68
32
N99
ICPC
Neurological disease other
45.1
90.4
54
13
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
15.5
90.2
82
60
N28
ICPC
Limited function/disability (N)
41.9
88.7
54
14
N18
ICPC
Paralysis/weakness
37.4
87.7
55
16
3430A
ICD-9 Finland
Infantile cerebral palsy, Diplegic
+∞
83.1
78
*
N03AG01
ATC
valproic acid; systemic, rectal
7.3
82.8
138
230
3431A
ICD-9 Finland
Infantile cerebral palsy, Hemiplegic
+∞
77.6
73
*
N03AX14
ATC
levetiracetam; systemic
12.3
76.8
80
73
N05BA01
ATC
diazepam; systemic, rectal
5.7
75.4
171
383
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
34.4
74.8
48
15
183
Kela drug reimbursment
Lamotrigin and topiramate
18.9
73.0
59
34
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
6.7
71.6
128
228
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
17.4
70.1
59
37
34300
ICD-8 Finland
Cerebral spastic infantile paralysis, Hemiplegia spastica
+∞
70.1
66
*
L28
ICPC
Limited function/disability (L)
5.7
69.5
153
332
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
16.5
68.2
59
39
34301
ICD-8 Finland
Cerebral spastic infantile paralysis, Diplegia spastica
+∞
65.7
62
*
A28
ICPC
Limited function/disability NOS
5.8
65.5
139
291
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
27.6
63.9
44
17
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
15.2
62.0
56
40
P85
ICPC
Mental retardation
25.5
60.6
43
18
34309
ICD-8 Finland
Cerebral spastic infantile paralysis, Unspecified
+∞
60.3
57
*
N03AF02
ATC
oxcarbazepine; oral
8.2
60.3
86
119
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
5.0
56.3
141
339
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
4.8
55.2
145
362
G81.1
ICD-10 Finland
Spastic hemiplegia
+∞
55.0
52
*
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
17.8
54.4
45
27
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
5.3
53.8
123
273
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
23.0
52.9
39
18
G81.9
ICD-10 Finland
Hemiplegia, unspecified
+∞
50.7
48
*
G80.8
ICD-10 Finland
Other cerebral palsy
+∞
50.7
48
*
RT150, ,
NOMESCO Finland
19.1
47.6
38
21
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.6
47.6
99
201
N05CD08
ATC
midazolam; nasal, systemic
9.8
47.5
57
63
34308
ICD-8 Finland
Cerebral spastic infantile paralysis, Alia definita
+∞
45.3
43
*
N03AF01
ATC
carbamazepine; oral, rectal
7.8
45.3
66
93
G80.3
ICD-10 Finland
Dyskinetic cerebral palsy
+∞
44.3
42
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
4.2
41.3
129
364
N03AE01
ATC
clonazepam; systemic
6.1
38.3
70
125
ZX114
NOMESCO Finland
Intramuscular
10.1
35.4
41
43
3438X
ICD-9 Finland
Infantile cerebral palsy, Other specified infantile cerebral palsy[PARESIS CEREBRALIS INFANTILIS ALIA DEFINITA]
+∞
34.7
33
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
9.2
33.1
41
47
A06AD11
ATC
lactulose; oral
4.0
32.4
103
292
Z3229
NOMESCO Finland
Other healthcare associate professional
4.1
32.2
97
264
R1250
NOMESCO Finland
Evaluation of functional capability
8.6
31.9
42
52
R5110, ,
SPAT
6.3
31.8
56
96
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
7.5
31.7
47
67
34302
ICD-8 Finland
Cerebral spastic infantile paralysis, Tetraplegia spastica
+∞
31.5
30
*
G82.4
ICD-10 Finland
Spastic tetraplegia
+∞
31.5
30
*
NF1DA
NOMESCO Finland
X-ray of hips
11.5
31.3
33
30
NFL22
NOMESCO Finland
Myotomy or tenotomy of hip or thigh
115.6
30.9
33
*
Z3226
NOMESCO Finland
Physiotherapist
3.0
30.5
173
704
G40.10
ICD-10 Finland
Simple partial seizures
47.4
29.9
36
8
XKC03
NOMESCO Finland
Water cystometry
8.9
29.9
38
45
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
5.8
29.8
57
106
N03AX09
ATC
lamotrigine; oral
4.2
29.5
86
228
G80
ICD-10 Finland
Cerebral palsy
+∞
29.4
28
*
F82
ICD-10 Finland
Specific developmental disorder of motor function
9.0
28.6
36
42
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
11.6
28.6
30
27
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
11.6
27.7
29
26
N29
ICPC
Neurological sympt/complt other
10.4
27.6
31
31
9375
FHL
Achilles tendon dissection or extension
+∞
27.3
26
*
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
4.8
26.8
64
145
EBA15
NOMESCO Finland
Extraction of multiple teeth
5.9
26.7
50
91
H50.31
ICD-10 Finland
Intermittent exotropia
9.1
26.5
33
38
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
5.9
26.2
49
89
N03AG04
ATC
vigabatrin; oral
97.3
25.8
28
*
R4110
NOMESCO Finland
Physiotherapy
2.5
25.6
210
1020
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
25.3
209
1018
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.0
25.2
136
533
SPAT1215
SPAT
Assessment of need for medical rehabilitation
5.7
25.1
48
89
H47.2
ICD-10 Finland
Optic atrophy
93.7
24.8
27
*
XA800
NOMESCO Finland
Neuropsychological investigation
4.1
24.7
73
195
N03AX11
ATC
topiramate; oral
5.4
24.7
50
98
U04
ICPC
Incontinence urine
6.3
24.5
42
70
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.4
23.7
94
307
Z2446
NOMESCO Finland
Social worker
3.2
23.3
101
348
3AX01, ,
NOMESCO Finland
37.8
23.2
29
8
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
22.8
242
1310
R4120
NOMESCO Finland
Occupational therapy
3.8
22.7
75
217
NE1AA
NOMESCO Finland
Pelvis X-ray examination
4.9
22.6
51
110
F80.1
ICD-10 Finland
Expressive language disorder
6.9
22.3
35
53
R1260
NOMESCO Finland
Evaluation of communicative skills
8.2
22.3
30
38
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.0
22.2
111
415
N39.4
ICD-10 Finland
Other specified urinary incontinence
4.6
22.0
55
129
Z2445
NOMESCO Finland
Psychologist
3.5
21.8
82
258
AA1AD
NOMESCO Finland
CT of head and brain
2.6
21.8
148
651
F83
ICD-10 Finland
Mixed specific developmental disorders
6.4
21.8
37
61
G40
ICD-10 Finland
Epilepsy
9.0
21.7
27
31
G91.1
ICD-10 Finland
Obstructive hydrocephalus
35.1
21.3
27
8
3439X
ICD-9 Finland
Infantile cerebral palsy, unspecified
+∞
20.9
20
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.0
20.9
102
376
181
Kela drug reimbursment
Retigabine and vigabatrin
113.6
20.7
22
*
RS142, ,
NOMESCO Finland
113.6
20.7
22
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.2
20.7
44
90
K59.09
ICD-10 Finland
Constipation, unspecified
4.1
20.6
60
158
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
8.5
20.6
27
33
Z02.7
ICD-10 Finland
Issue of medical certificate
3.6
20.6
74
226
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
19.1
20.6
31
17
TJD20
NOMESCO Finland
Change of gastrostomy tube
26.5
20.6
28
11
Z50.1
ICD-10 Finland
Other physical therapy
5.0
20.1
45
96
37300
ICD-8 Finland
Strabismus, Concomitans convergens
24.3
20.1
28
12
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.4
20.0
76
241
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
19.9
170
830
N03AX18
ATC
lacosamide; systemic
17.0
19.8
31
19
RT274, ,
NOMESCO Finland
108.3
19.7
21
*
NHL14
NOMESCO Finland
Shortening or lengthening of achilles tendon
22.4
19.6
28
13
RT490, ,
NOMESCO Finland
41.5
19.6
24
6
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
19.5
154
725
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.9
19.4
99
374
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.4
19.3
73
230
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.6
19.3
67
200
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
4.3
19.3
51
125
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
19.1
148
689
R62.0
ICD-10 Finland
Delayed milestone
5.5
19.1
38
73
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
56.8
19.0
22
*
G80.4
ICD-10 Finland
Ataxic cerebral palsy
+∞
18.8
18
*
34304
ICD-8 Finland
Cerebral spastic infantile paralysis, Dystonia tetraplegica. Tonusväxlingssyndrom
+∞
18.8
18
*
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
21.6
18.7
27
13
H50.30
ICD-10 Finland
Intermittent esotropy
15.6
18.6
30
20
602
Kela drug reimbursment
Children's severe malnutrition
6.6
18.5
30
47
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
6.6
18.5
30
47
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
31.0
18.4
24
8
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.1
18.4
84
297
G40.89
ICD-10 Finland
Other epilepsy
18.2
18.4
28
16
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
45.4
18.3
22
5
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
45.4
18.3
22
5
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.5
18.2
67
208
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
6.5
18.1
30
48
RT190, ,
NOMESCO Finland
54.1
18.0
21
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
17.1
18.0
28
17
3454A
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[EPILEPSIA GENERALISATA SECUNDARIA]
97.7
17.6
19
*
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.7
17.6
59
172
G91.0
ICD-10 Finland
Communicating hydrocephalus
43.2
17.4
21
5
7803A
ICD-9 Finland
General symptoms, Convulsions
7.4
17.1
25
35
M41.4
ICD-10 Finland
Neuromuscular scoliosis
26.4
17.0
23
9
H53.0
ICD-10 Finland
Amblyopia ex anopsia
6.3
17.0
29
48
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.9
16.9
86
323
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
4.1
16.8
47
120
9362
FHL
Adductorotomy
+∞
16.7
16
*
G81.0
ICD-10 Finland
Flaccid hemiplegia
+∞
16.7
16
*
34409
ICD-8 Finland
Other cerebral paralysis, Unspecified
+∞
16.7
16
*
3432A
ICD-9 Finland
Infantile cerebral palsy, Quadriplegic[CP-OIREYHTYMÄ,TETRAPLEGIA SPASTICA]
+∞
16.7
16
*
K59.0
ICD-10 Finland
Constipation
4.1
16.6
47
121
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.4
16.6
136
647
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.8
16.2
51
142
SPAT1262
SPAT
Handing over of treatment supplies
2.6
16.1
101
423
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.5
16.1
58
177
RL140, ,
NOMESCO Finland
19.1
16.1
24
13
SPAT1234
SPAT
Support of social functional capacity
4.2
16.0
44
111
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.1
15.9
189
1045
OAB43, ,
SPAT
0.4
15.9
90
1903
R60.0
ICD-10 Finland
Localized oedema
3.2
15.9
65
215
G40.1
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
61.6
15.8
18
*
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
7.1
15.8
24
35
3432B
ICD-9 Finland
Infantile cerebral palsy, Quadriplegic[CP-OIREYHTYMÄ,DYSTONIA TETRAPLEGICA]
+∞
15.7
15
*
7819X
ICD-9 Finland
Symptoms involving nervous and musculoskeletal systems, Other symptoms involving nervous and musculoskeletal systems[SYMPTOMATA ALIA SYSTEMATIS NERVORUM ET MUSCULOSCEL]
27.0
15.7
21
8
R33
ICD-10 Finland
Retention of urine
4.1
15.5
43
109
N88
ICPC
Epilepsy
11.6
15.4
28
25
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
6.1
15.4
27
46
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.7
15.1
85
337
G40.00
ICD-10 Finland
Benign childhood epilepsy with centrotemporal EEG spikes
58.0
14.8
17
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.9
14.8
74
275
H50.0
ICD-10 Finland
Convergent concomitant strabismus
6.3
14.8
25
41
G04BD08
ATC
solifenacin; oral
4.4
14.7
37
87
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
5.8
14.7
27
48
H47.7
ICD-10 Finland
Disorder of visual pathways, unspecified
+∞
14.6
14
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.2
14.6
60
199
K03.66
ICD-10 Finland
Tooth plaque
2.7
14.6
88
361
N85
ICPC
Congenital anomaly neurological
153.2
14.5
15
*
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
4.7
14.4
34
76
NFK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of femur
27.9
14.3
19
7
RS222, ,
NOMESCO Finland
10.8
14.3
27
26
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.7
14.2
84
341
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
43.5
14.2
17
*
SPAT1216
SPAT
Assessment of functional ability
2.7
14.0
79
313
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.8
13.8
74
286
A41.9
ICD-10 Finland
Sepsis, unspecified
4.7
13.7
32
71
U07
ICPC
Urine symptom/complaint other
3.3
13.6
53
170
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
34.8
13.6
17
5
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
16.6
13.5
21
13
G82.1
ICD-10 Finland
Spastic paraplegia
142.8
13.5
14
*
F72.0
ICD-10 Finland
Severe mental retardation, with the statement of no, or minimal, impairment of behaviour
142.8
13.5
14
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
13.2
13.5
23
18
R4130
NOMESCO Finland
Speech therapy
4.3
13.4
35
85
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.8
13.3
69
261
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.6
13.2
80
329
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
17.1
13.0
20
12
TLC00
NOMESCO Finland
Insertion of intrauterine device
3.0
13.0
61
219
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.4
12.7
92
412
A46
ICD-10 Finland
Erysipelas
2.6
12.6
78
324
G82.2
ICD-10 Finland
Paraplegia, unspecified
+∞
12.5
12
*
34400
ICD-8 Finland
Other cerebral paralysis, Hemiplegia NUD
+∞
12.5
12
*
34305
ICD-8 Finland
Cerebral spastic infantile paralysis, Ataxia
+∞
12.5
12
*
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
24.9
12.5
17
7
R5120
NOMESCO Finland
Preparation of an aid
5.8
12.5
23
41
P21.0
ICD-10 Finland
Severe birth asphyxia
132.4
12.5
13
*
R11
ICD-10 Finland
Nausea and vomiting
2.5
12.3
81
346
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
4.5
12.3
30
69
NHG22
NOMESCO Finland
Fusion of subtalar joint
38.3
12.2
15
*
113
Kela drug reimbursment
Anxiety disorders associated with mental retardation
38.3
12.2
15
*
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
38.3
12.2
15
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
12.2
229
1465
N03AX12
ATC
[U] gabapentin; oral
2.3
12.2
96
446
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
8.9
12.1
25
29
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
27.3
12.1
16
6
WX892
NOMESCO Finland
Monitored bed care
2.9
12.0
59
217
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
5.0
12.0
26
54
L89
ICD-10 Finland
Decubitus ulcer and pressure area
15.0
11.8
19
13
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
3.7
11.8
37
103
A03FA02
ATC
cisapride; oral, rectal
3.3
11.8
46
148
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
11.6
102
495
3459X
ICD-9 Finland
Epilepsy, unspecified
23.4
11.6
16
7
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
11.4
11.6
21
19
ZXA00
NOMESCO Finland
Right side
2.1
11.6
132
711
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.7
11.5
66
263
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
122.0
11.5
12
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.0
11.3
50
173
UKC02
NOMESCO Finland
Cystoscopy
2.6
11.3
70
290
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
35.7
11.3
14
*
G04BD04
ATC
oxybutynin; oral, transdermal
3.6
11.3
38
111
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
13.0
11.2
19
15
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
20.4
11.2
16
8
TKC20
NOMESCO Finland
Catheterisation of bladder
3.4
11.1
41
127
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
11.0
132
722
37301
ICD-8 Finland
Strabismus, Concomitans divergens
14.2
11.0
18
13
JDB00
NOMESCO Finland
Gastrostomy
44.1
10.9
13
*
ZXA05
NOMESCO Finland
Left side
2.1
10.9
120
636
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
12.2
10.9
19
16
H54.7
ICD-10 Finland
Unspecified visual loss
10.8
10.8
20
19
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
9.8
10.8
21
22
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
18.2
10.8
16
9
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.5
10.7
74
323
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
13.2
10.7
18
14
A82
ICPC
Secondary effect of trauma
61.0
10.7
12
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
10.6
226
1489
H52.2
ICD-10 Finland
Astigmatism
3.9
10.6
31
82
SPAT1301
SPAT
No procedures
1.8
10.6
190
1189
RS211, ,
NOMESCO Finland
9.4
10.6
21
23
G03DC03
ATC
lynestrenol; oral
4.8
10.5
24
52
NH1AD
NOMESCO Finland
Ankle and foot CT
5.5
10.5
20
37
N03AA02
ATC
phenobarbital; systemic
111.7
10.4
11
*
RT320, ,
NOMESCO Finland
111.7
10.4
11
*
N31.0
ICD-10 Finland
Uninhibited neuropathic bladder, not elsewhere classified
111.7
10.4
11
*
G82.5
ICD-10 Finland
Tetraplegia, unspecified
+∞
10.4
10
*
7423A
ICD-9 Finland
Other congenital anomalies of nervous system, Congenital hydrocephalus
+∞
10.4
10
*
NEK20
NOMESCO Finland
Fenestration or forage of bone of pelvis
+∞
10.4
10
*
F73.0
ICD-10 Finland
Profound mental retardation, with the statement of no, or minimal, impairment of behaviour
+∞
10.4
10
*
SPAT1260
SPAT
Consultation of another employee
2.1
10.4
112
588
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.3
10.4
39
122
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
4.4
10.4
26
61
78159
ICD-8 Finland
Other symptoms referable to nervous system and special senses, Laesio loquendi alia sive NUD
33.1
10.4
13
*
WX704
NOMESCO Finland
Intubation
2.7
10.3
58
229
WX002
NOMESCO Finland
Sedation and analgesia
2.1
10.2
100
507
N05AX08
ATC
risperidone; systemic
2.5
10.1
69
300
N05CD07
ATC
temazepam; oral
2.8
10.0
51
191
L17
ICPC
Foot/toe symptom/complaint
1.8
10.0
177
1101
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
4.3
10.0
26
63
R47.1
ICD-10 Finland
Dysarthria and anarthria
17.0
9.9
15
9
N03AX22
ATC
perampanel; oral
17.0
9.9
15
9
N04AA02
ATC
biperiden; systemic
5.3
9.9
20
39
Z3231
NOMESCO Finland
Registered nurse
1.8
9.9
191
1219
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.0
9.8
45
159
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.1
9.8
97
493
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.7
9.7
54
212
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
55.8
9.7
11
*
Z43.5
ICD-10 Finland
Attention to cystostomy
55.8
9.7
11
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.7
9.6
53
207
SPAT1231
SPAT
Assessment of adjustments needed in living environment
8.6
9.6
20
24
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.6
9.6
31
88
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.9
9.6
46
167
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
101.4
9.4
10
*
G41.9
ICD-10 Finland
Status epilepticus, unspecified
17.8
9.4
14
8
N03AX23
ATC
brivaracetam; systemic
17.8
9.4
14
8
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
30.5
9.4
12
*
H81
ICPC
Excessive ear wax
2.2
9.4
83
403
P07.3
ICD-10 Finland
Other preterm infants
4.5
9.4
23
53
34408
ICD-8 Finland
Other cerebral paralysis, Alia definita
+∞
9.4
9
*
34401
ICD-8 Finland
Other cerebral paralysis, Diplegia NUD
+∞
9.4
9
*
P91.02
ICD-10 Finland
Neonatal hypoxic-ischaemic encephalopathy, severe
+∞
9.4
9
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
9.3
137
801
N06AB04
ATC
citalopram; systemic
2.0
9.3
117
650
N03AX15
ATC
zonisamide; oral
13.9
9.2
15
11
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.5
9.1
59
250
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
9.2
9.1
18
20
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
15.8
9.1
14
9
WX882
NOMESCO Finland
High dependency care
3.0
9.0
39
134
Q66.0
ICD-10 Finland
Talipes equinovarus
18.9
9.0
13
7
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.7
8.9
28
78
RD210, ,
NOMESCO Finland
3.4
8.9
31
93
JN3AD
NOMESCO Finland
Abdominal CT examination
2.4
8.9
61
266
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.1
8.8
36
119
N03AB02
ATC
phenytoin; systemic
10.9
8.8
16
15
TJF80
NOMESCO Finland
Ostomy education
10.9
8.8
16
15
L16
ICPC
Ankle symptom/complaint
2.1
8.8
92
478
N05AA02
ATC
levomepromazine; systemic
3.3
8.7
32
99
H52.0
ICD-10 Finland
Hypermetropia
3.6
8.6
28
80
RK110, ,
NOMESCO Finland
11.8
8.6
15
13
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
9.2
8.6
17
19
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
8.6
113
637
ZXE00
NOMESCO Finland
One hour or less
1.7
8.5
243
1714
C03CA01
ATC
furosemide; systemic
2.0
8.5
93
490
G04BD12
ATC
mirabegron; oral
2.7
8.5
47
184
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
20.3
8.5
12
6
AAF00
NOMESCO Finland
Ventriculostomy
20.3
8.5
12
6
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
8.5
107
594
34532
ICD-8 Finland
Epilepsy, Partialis (focalis) generalisata
91.2
8.4
9
*
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
13.0
8.4
14
11
H47.6
ICD-10 Finland
Disorders of visual cortex
+∞
8.3
8
*
2133
FHL
Suntin revisio
+∞
8.3
8
*
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
7.2
8.3
19
27
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
8.3
129
767
4451
FHL
Guitar cutting
2.6
8.3
48
193
SPAT1312
SPAT
General health counselling
1.7
8.3
217
1497
OAB50, ,
SPAT
3.0
8.2
35
119
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.3
8.2
30
93
S97
ICPC
Chronic ulcer skin
3.4
8.2
29
88
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
4.8
8.2
18
38
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.7
8.1
44
171
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
17.4
8.1
12
7
H51.9
ICD-10 Finland
Disorder of binocular movement, unspecified
33.8
8.1
10
*
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
9.1
8.1
16
18
7651A
ICD-9 Finland
Disorders relating to short gestation and unspecified low birthweight, Other preterm infants[ENNENAIK SYNT SYNTYMÄP 1000-1499G/RASK KESTO 26-30H]
22.3
8.0
11
5
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
3.9
8.0
23
60
XKD03
NOMESCO Finland
Urethral pressure profilometry
7.4
8.0
18
25
RT130, ,
NOMESCO Finland
13.2
7.9
13
10
G04BD07
ATC
tolterodine; oral
3.9
7.9
23
61
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
8.6
7.8
16
19
N05AH03
ATC
olanzapine; systemic
2.3
7.8
62
288
N05AX12
ATC
aripiprazole; systemic
2.5
7.8
50
211
XCK00
NOMESCO Finland
Perimetry
3.0
7.8
33
112
N06AA09
ATC
amitriptyline; systemic
2.6
7.7
44
175
R5130, ,
SPAT
45.5
7.7
9
*
Q65.0
ICD-10 Finland
Congenital dislocation of hip, unilateral
45.5
7.7
9
*
Q04.8
ICD-10 Finland
Other specified congenital malformations of brain
45.5
7.7
9
*
R50.9
ICD-10 Finland
Fever, unspecified
1.9
7.7
116
681
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
7.7
52
225
D64.9
ICD-10 Finland
Anaemia, unspecified
2.6
7.7
45
182
RL130, ,
NOMESCO Finland
8.2
7.6
16
20
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
7.5
52
227
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.5
7.5
46
190
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.6
7.5
43
172
SPAT1240
SPAT
Therapeutic discussion
1.9
7.5
94
520
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.3
7.5
28
88
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
7.5
216
1520
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
3.3
7.5
27
83
H53.4
ICD-10 Finland
Visual field defects
6.6
7.5
18
28
9480
FHL
Tendon shortening and extension
81.0
7.4
8
*
K90
ICPC
Stroke/cerebrovascular accident
7.8
7.4
16
21
SPAT1153
SPAT
Removal of sutures
1.7
7.4
140
881
U05
ICPC
Urination problems other
3.2
7.4
29
94
S06.0
ICD-10 Finland
Concussion
2.0
7.3
87
472
ZXD05
NOMESCO Finland
Urgent procedure
1.7
7.3
184
1249
9372
FHL
Measures for knee flexors
+∞
7.3
7
*
P90
ICD-10 Finland
Convulsions of newborn
+∞
7.3
7
*
31599
ICD-8 Finland
Unspecified mental retardation, Other and unspecified
+∞
7.3
7
*
3199A
ICD-9 Finland
Unspecified mental retardation[MUU ÄLYLLINEN KEHITYSVAMMAISUUS,EI KÄYTTÄYTYMIHÄIRI]
+∞
7.3
7
*
RS221, ,
NOMESCO Finland
3.9
7.3
21
55
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
7.3
69
345
WX730
NOMESCO Finland
Conventional respirator
7.4
7.2
16
22
N06AX03
ATC
mianserin; oral
3.2
7.2
28
90
Q03.9
ICD-10 Finland
Congenital hydrocephalus, unspecified
30.4
7.2
9
*
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
30.4
7.2
9
*
F71.1
ICD-10 Finland
Moderate mental retardation, significant impairment of behaviour requiring attention or treatment
30.4
7.2
9
*
ADB00
NOMESCO Finland
Implantation of vagus nerve stimulating device
20.3
7.1
10
5
3451A
ICD-9 Finland
Epilepsy, Generalised convulsive epilepsy
20.3
7.1
10
5
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
20.3
7.1
10
5
XKD00
NOMESCO Finland
Uroflowmetry
2.2
7.1
58
273
S01.0
ICD-10 Finland
Open wound of scalp
2.4
7.1
47
202
Z50.5
ICD-10 Finland
Speech therapy
3.2
7.1
27
86
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.5
7.0
42
172
XX4AW, ,
NOMESCO Finland
6.4
7.0
17
27
B01AB05
ATC
enoxaparin; parenteral
1.8
6.9
127
790
F60.9
ICD-10 Finland
Personality disorder, unspecified
4.0
6.9
19
48
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.3
6.9
50
223
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
14.0
6.9
11
8
34599
ICD-8 Finland
Epilepsy, Other and unspecified
14.0
6.9
11
8
U07.2
ICD-10 Finland
COVID-19, virus not identified
0.5
6.9
70
1256
N03AX16
ATC
[U] pregabalin
1.8
6.8
109
651
WX402
NOMESCO Finland
General anaesthesia
1.7
6.8
137
876
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.9
6.8
93
530
P07.2
ICD-10 Finland
Extreme immaturity
16.9
6.8
10
6
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
3.4
6.7
24
73
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.3
6.7
50
226
NF1AA
NOMESCO Finland
Hip X-ray examination
2.8
6.7
33
122
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
6.0
6.6
17
29
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
3.6
6.6
21
59
OAA67, ,
SPAT
0.4
6.6
34
786
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.7
6.6
34
129
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
8.8
6.6
13
15
SPAT1284
SPAT
Extensive health certificate
3.1
6.6
27
90
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
6.5
133
851
Z2221
NOMESCO Finland
Medical doctor
1.6
6.5
171
1171
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
7.5
6.4
14
19
7690A
ICD-9 Finland
Respiratory distress syndrome[VASTASYNTYNEEN IRD-OIREYHTYMÄ]
70.5
6.4
7
*
RS140, ,
NOMESCO Finland
14.5
6.4
10
7
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
14.5
6.4
10
7
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.1
6.4
57
278
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
6.6
6.4
15
23
H61.2
ICD-10 Finland
Impacted cerumen
2.4
6.3
41
174
SPAT1310
SPAT
Counselling related to known health issue
1.6
6.3
189
1331
SPAT1263
SPAT
Sampling
1.5
6.3
253
1906
SPAT1293
SPAT
Other function in accordance with rehabilitation guidance nomenclature
18.2
6.3
9
5
9370
FHL
Femoral osteotomy
+∞
6.3
6
*
P52.2
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 3, and grade 4 of fetus and newborn
+∞
6.3
6
*
RK321, ,
NOMESCO Finland
+∞
6.3
6
*
F71.9
ICD-10 Finland
Moderate mental retardation, without mention of impairment of behaviour
+∞
6.3
6
*
Q80.2
ICD-10 Finland
Lamellar ichthyosis
+∞
6.3
6
*
74200
ICD-8 Finland
Congenital hydrocephalus, Communicans
+∞
6.3
6
*
4122
FHL
Tympanostomy (tympanic tube)
3.1
6.3
25
82
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
7.1
6.2
14
20
G91.8
ICD-10 Finland
Other hydrocephalus
26.9
6.2
8
*
N05AH04
ATC
quetiapine; oral
1.7
6.2
136
886
U13
ICPC
Bladder symptom/complaint other
3.7
6.2
19
52
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
6.2
90
521
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.5
6.2
37
151
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
6.2
107
654
WX725
NOMESCO Finland
Noninvasive ventilation
2.5
6.1
36
146
N06AA12
ATC
doxepin; systemic
2.8
6.1
29
105
D01AE15
ATC
terbinafine; topical
2.6
6.1
34
134
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.9
6.1
28
100
ZX198
NOMESCO Finland
Other local administration
10.1
6.0
11
11
R13
ICD-10 Finland
Dysphagia
2.5
6.0
36
147
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
3.9
6.0
17
44
R32
ICD-10 Finland
Unspecified urinary incontinence
3.9
6.0
17
44
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
274
1578
2.25
22.10
10.2
8.7
1.21
1.12
inr
0.71
76
490
303
1916
2.07
18.33
13.6
8.3
1.21
1.22
mmol/l
1.06
281
1795
276
1693
2.08
18.06
7.0
5.8
35.56
37.27
g/l
4.58
256
1604
255
1543
2.06
17.11
5.1
3.3
—
—
—
0
0
318
2097
1.99
16.63
12.6
8.1
1.21
1.22
mmol/l
0.75
280
1843
92
373
2.70
15.64
7.7
11.0
0.91
0.83
mmol/l
0.06
72
298
198
1144
2.04
14.68
3.5
2.1
237.82
266.18
u/l
0.16
191
1089
90
375
2.62
14.46
7.8
11.0
5.13
5.22
kpa
0.29
84
354
90
375
2.62
14.46
7.8
10.9
13.99
13.30
kpa
0.44
84
356
372
2668
1.90
14.40
7.9
5.5
6.35
6.37
mmol/l
0.05
351
2436
163
901
2.07
13.49
4.0
2.7
8.09
7.16
e6/l
0.28
152
800
130
669
2.17
12.91
5.6
5.7
0.81
0.82
mmol/l
0.77
120
639
212
1310
1.91
12.64
3.0
2.6
53.81
59.69
u/l
0.75
193
1232
122
618
2.19
12.59
2.6
1.9
—
—
—
0
0
217
1358
1.89
12.40
5.1
3.3
46.43
53.98
e6/l
0.14
176
1016
583
5013
2.34
11.88
22.8
11.5
139.41
139.58
mmol/l
0.85
573
4884
583
5026
2.31
11.59
22.5
11.6
3.94
3.94
mmol/l
0.02
571
4873
197
1228
1.86
11.21
4.9
3.2
0.38
0.37
e6/l
0.04
156
904
308
2201
1.74
11.00
5.7
6.4
11.10
14.09
umol/l
1.94
284
2085
82
378
2.33
10.53
2.7
4.6
352.60
272.02
u/l
0.46
77
365
23
49
4.83
10.31
3.7
1.2
—
—
—
0
0
95
472
2.18
10.19
19.2
7.2
1.39
1.13
mmol/l
0.29
70
334
88
425
2.23
10.12
2.4
1.8
—
—
—
0
0
94
468
2.17
10.03
8.0
8.4
104.56
104.49
mmol/l
0.05
94
468
178
1112
1.82
9.89
2.6
2.5
2.86
2.81
mg/l
0.08
152
971
104
545
2.08
9.71
7.4
7.6
1.38
1.39
mmol/l
0.00
89
424
392
3067
1.68
9.47
7.4
3.7
3960.62
1501.71
e6/l
0.39
13
41
87
431
2.17
9.38
2.7
1.9
—
—
—
0
0
64
280
2.42
9.23
2.4
1.7
—
—
—
0
0
125
718
1.91
8.97
4.5
3.0
153.17
579.80
ng/l
1.60
87
449
172
1100
1.76
8.69
2.9
2.3
—
—
—
0
0
427
3461
1.65
8.59
8.2
6.7
93.04
83.66
u/l
1.20
401
3275
17
19
9.15
8.57
2.9
2.5
34.23
31.07
umol/l
0.58
12
14
290
2142
1.63
8.46
3.0
2.6
—
—
—
0
0
17
21
8.28
8.12
2.1
2.1
23.12
17.24
umol/l
0.87
17
21
114
657
1.89
8.05
3.3
2.5
13.29
14.52
umol/l
0.89
106
618
106
600
1.91
7.90
3.2
2.5
2.48
2.45
g/l
0.16
98
563
122
726
1.83
7.78
4.3
3.0
4.74
2.46
e6/l
1.03
58
370
123
745
1.80
7.38
4.1
2.9
1.15
0.77
e6/l
0.97
60
392
21
55
3.91
7.30
1.1
1.4
—
—
—
0
0
75
390
2.04
7.11
18.0
7.4
24.22
24.28
mmol/l
0.08
75
384
96
546
1.89
7.03
3.5
2.6
21.39
23.65
%
0.77
80
485
234
1709
1.57
6.79
4.0
3.6
43.44
32.04
u/l
0.65
222
1631
52
241
2.26
6.60
1.4
1.4
—
—
—
0
0
93
535
1.86
6.56
1.7
1.6
1067.60
1141.84
nmol/l
0.34
70
423
19
51
3.81
6.40
8.1
5.7
11.29
10.18
mg/l
0.38
19
46
17
31
5.60
6.33
3.1
1.2
—
—
—
0
0
190
1341
1.58
6.31
2.9
2.9
2.35
2.36
mmol/l
0.80
171
1228
50
234
2.23
6.21
2.9
2.7
138.52
135.34
ng/l
0.02
44
209
32
122
2.71
6.15
1.9
2.7
1.19
1.21
g/l
0.06
27
106
13
17
7.78
6.14
3.8
2.5
1.13
1.13
umol/l
0.00
13
17
72
392
1.94
6.00
7.3
5.9
—
—
—
0
0
19
54
3.59
5.92
3.0
1.4
1.16
1.44
promille
0.27
13
41
85
1373
0.56
5.78
1.9
2.3
—
—
—
0
0
33
133
2.56
5.70
2.7
2.1
41.22
7.56
e6/l
0.45
23
91
33
133
2.56
5.70
2.7
2.1
949.17
153.53
e6/l
0.47
24
97
43
198
2.25
5.57
2.8
1.7
—
—
—
0
0
121
795
1.64
5.32
1.7
1.4
23.76
20.40
nmol/l
1.16
104
695
253
1959
1.47
5.28
3.5
2.6
72.87
71.68
nmol/l
0.26
234
1836
77
1249
0.57
5.26
1.8
2.1
—
—
—
0
0
67
378
1.86
5.03
3.8
2.6
—
—
—
0
0
93
582
1.70
4.92
1.9
2.4
2.45
2.42
mmol/l
1.85
75
501
114
761
1.60
4.68
3.1
3.5
1291.53
775.29
ng/l
0.30
90
624
45
231
2.02
4.46
6.8
7.6
130.78
130.00
g/l
0.09
45
226
33
656
0.48
4.30
1.5
1.5
—
—
—
0
0
26
109
2.44
4.19
1.6
1.3
—
—
—
0
0
24
97
2.53
4.17
1.2
2.4
—
—
—
0
0
24
99
2.48
4.01
2.3
1.9
—
—
—
0
0
24
99
2.48
4.01
2.3
1.9
—
—
—
0
0
104
705
1.56
3.99
1.6
1.6
170588686.02
10987687.46
pmol/l
0.45
85
628
86
560
1.62
3.91
3.0
4.4
5.92
7.35
umol/l
0.60
65
469
146
1070
1.47
3.87
2.9
2.3
3.20
1.06
mg/l
1.37
115
762
188
1447
1.42
3.83
2.2
1.7
84.70
95.77
pmol/l
3.41
112
793
295
2462
1.36
3.64
3.4
2.9
299.60
85.03
ug/l
0.61
266
2335
18
69
2.65
3.49
4.2
2.6
15.93
17.38
%
0.87
11
35
20
81
2.51
3.49
2.2
1.8
—
—
—
0
0
20
81
2.51
3.49
2.2
1.8
—
—
—
0
0
171
1321
1.40
3.36
3.4
2.9
23.81
44.21
ng/l
0.75
118
670
41
228
1.85
3.28
2.4
2.2
8.24
7.74
ug/l
0.07
32
209
38
208
1.88
3.20
4.9
2.8
0.07
0.10
e6/l
0.34
38
200
19
79
2.45
3.16
2.4
1.6
—
—
—
0
0
35
188
1.91
3.12
7.2
7.1
0.64
0.65
%
0.06
35
188
20
86
2.37
3.10
2.9
2.8
127.53
131.57
g/l
0.25
15
67
286
2417
1.32
3.10
5.1
3.0
0.00
0.00
estimate
0.80
59
459
353
3076
1.32
3.05
12.8
9.1
4.10
3.87
e9/l
1.11
313
2684
138
1779
0.72
3.03
1.8
1.7
—
—
—
0
0
157
1217
1.38
3.00
6.2
3.2
0.00
0.01
estimate
1.08
59
436
11
31
3.59
3.00
2.0
1.5
—
—
—
0
0
14
51
2.78
3.00
2.1
1.7
—
—
—
0
0
16
63
2.58
2.97
2.1
1.7
—
—
—
0
0
285
2431
1.30
2.81
5.2
3.1
0.00
0.00
estimate
-0.00
61
426
15
59
2.58
2.80
2.7
1.7
—
—
—
0
0
282
2403
1.30
2.80
6.7
4.3
0.00
0.00
estimate
0.50
59
455
26
131
2.02
2.79
2.7
1.8
—
—
—
0
0
17
72
2.40
2.74
2.5
1.6
—
—
—
0
0
21
98
2.18
2.73
1.6
1.3
—
—
—
0
0
437
4754
0.76
2.70
3.5
3.7
—
—
—
0
0
52
786
0.63
2.60
1.6
2.1
—
—
—
0
0
62
898
0.66
2.55
1.4
1.5
—
—
—
0
0
20
95
2.14
2.51
2.2
1.8
—
—
—
0
0
15
323
0.45
2.50
1.5
1.5
—
—
—
0
0
11
37
3.01
2.49
1.8
1.8
—
—
—
0
0
11
37
3.01
2.49
1.8
1.8
—
—
—
0
0
11
37
3.01
2.49
1.8
1.8
—
—
—
0
0
39
624
0.60
2.49
1.5
2.0
—
—
—
0
0
161
1288
1.33
2.48
3.9
3.7
7.57
8.60
mmol/l
1.68
140
1152
8
21
3.84
2.47
1.4
1.6
1.96
0.90
nmol/l
—
8
16
64
436
1.52
2.44
2.4
2.4
30.12
144.55
u/l
0.52
50
367
120
921
1.37
2.42
3.8
4.1
11.11
11.84
mg/mmol
0.06
77
614
13
52
2.53
2.37
1.8
1.3
—
—
—
0
0
8
22
3.67
2.37
1.5
1.3
—
—
—
0
0
8
22
3.67
2.37
1.5
1.3
—
—
—
0
0
11
39
2.85
2.35
6.5
4.0
22.27
26.62
umol/l
0.95
11
39
25
134
1.90
2.29
2.6
1.8
—
—
—
0
0
13
53
2.48
2.29
1.8
1.3
—
—
—
0
0
13
53
2.48
2.29
1.8
1.3
—
—
—
0
0
13
53
2.48
2.29
1.8
1.3
—
—
—
0
0
21
107
1.99
2.22
2.4
1.5
—
—
—
0
0
14
295
0.46
2.22
1.4
1.4
—
—
—
0
0
14
294
0.46
2.20
1.4
1.4
—
—
—
0
0
14
293
0.47
2.19
1.4
1.4
—
—
—
0
0
14
293
0.47
2.19
1.4
1.4
—
—
—
0
0
13
55
2.39
2.13
1.7
1.6
—
—
—
0
0
305
2690
1.25
2.12
9.1
6.5
53.69
54.36
%
0.41
288
2578
308
2722
1.25
2.09
9.5
6.7
31.01
31.18
%
0.09
292
2612
561
5324
1.35
2.06
21.0
10.6
25.68
21.07
mg/l
2.53
465
3990
431
3958
1.25
2.05
4.4
3.8
14.60
14.46
pmol/l
0.50
386
3681
27
156
1.76
1.99
2.1
2.0
—
—
—
0
0
19
98
1.97
1.97
2.0
1.3
—
—
—
0
0
19
98
1.97
1.97
2.0
1.3
—
—
—
0
0
12
51
2.38
1.96
1.9
1.4
—
—
—
0
0
25
142
1.79
1.95
2.2
1.9
—
—
—
0
0
135
1090
1.30
1.93
5.1
3.1
1.02
1.02
kg/l
0.04
18
157
36
547
0.64
1.88
1.6
1.5
—
—
—
0
0
6
17
3.55
1.84
3.3
3.1
192.50
165.37
ug/l
—
6
17
12
53
2.29
1.81
1.9
1.3
—
—
—
0
0
16
80
2.02
1.81
2.1
1.6
—
—
—
0
0
7
23
3.06
1.80
5.9
6.7
—
—
—
0
0
495
4651
1.25
1.76
5.0
4.3
4.34
2.08
mu/l
0.44
446
4393
18
97
1.88
1.67
1.2
1.3
5.31
4.09
u/ml
0.15
13
46
10
40
2.52
1.67
4.1
3.0
37750.00
39957.63
ug/l
—
10
40
6
19
3.18
1.66
1.7
1.3
—
—
—
0
0
6
19
3.18
1.66
1.7
1.3
—
—
—
0
0
14
69
2.05
1.65
2.0
1.4
—
—
—
0
0
8
32
2.52
1.60
1.6
1.0
—
—
—
0
0
5
15
3.35
1.52
1.8
1.1
—
—
—
0
0
444
4710
0.83
1.50
3.8
3.5
1.38
1.42
mmol/l
1.10
411
4480
17
94
1.83
1.48
2.7
2.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
37
2.45
1.48
1.4
1.1
—
—
—
0
0
570
5481
1.28
1.44
11.9
8.6
30.25
28.16
u/l
0.68
552
5345
23
362
0.62
1.44
1.6
1.4
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
17
95
1.81
1.44
5.2
7.1
0.28
0.32
u/ml
—
10
55
10
194
0.51
1.33
1.1
1.3
—
—
—
0
0
21
131
1.62
1.25
1.4
1.4
311.57
348.16
ug/g
0.43
14
75
5
19
2.64
1.22
2.2
2.1
—
—
—
0
0
5
19
2.64
1.22
2.2
2.1
—
—
—
0
0
8
37
2.18
1.21
1.1
1.1
—
—
—
0
0
507
4842
1.20
1.20
23.6
13.4
14.93
14.00
%
2.92
498
4785
7
31
2.27
1.10
1.4
2.0
115.86
126.13
%
—
7
31
23
337
0.67
1.08
1.5
1.9
—
—
—
0
0
7
32
2.20
1.08
1.6
1.1
—
—
—
0
0
39
520
0.73
1.08
1.9
2.5
0.93
0.75
ug/l
0.18
21
265
16
97
1.67
1.07
2.8
3.8
9.72
23.92
mg/l
3.78
11
66
18
277
0.64
1.07
1.5
1.4
—
—
—
0
0
10
52
1.94
1.06
7.1
9.8
0.73
0.58
mmol/l
—
10
47
102
860
1.22
1.04
2.7
2.8
228.30
115.47
ug/g
0.78
86
688
10
53
1.90
1.01
2.8
1.3
—
—
—
0
0
0
32
0.00
0.95
0.0
2.7
—
—
—
0
0
15
94
1.61
0.91
1.3
1.3
10.14
6.29
u/ml
—
7
38
378
3569
1.14
0.90
4.2
3.7
11.35
8.81
mm/h
2.91
351
3346
18
120
1.51
0.86
6.0
3.6
26.72
23.63
nmol/l
0.40
18
115
29
388
0.74
0.85
1.4
1.3
—
—
—
0
0
54
435
1.26
0.85
4.0
3.3
30.50
30.45
%
0.01
36
319
200
1818
1.14
0.84
5.6
3.0
—
—
—
0
0
43
338
1.29
0.82
2.1
1.6
547.61
312.02
mu/l
1.34
38
304
6
32
1.88
0.82
1.0
3.6
—
—
—
0
0
6
32
1.88
0.82
1.0
3.6
—
—
—
0
0
16
235
0.67
0.80
1.1
1.2
3.46
2.45
u/ml
0.17
11
153
6
33
1.83
0.79
1.0
1.2
—
—
—
0
0
6
33
1.83
0.79
9.8
2.0
—
—
—
0
0
460
4417
1.13
0.79
14.1
8.8
102.26
94.73
ml/min/173m2
7.63
353
3482
131
1161
1.16
0.78
1.6
1.7
1.54
1.38
mmol/l
0.93
117
1029
36
458
0.77
0.76
1.3
1.3
77.51
164.51
iu/ml
1.61
19
174
459
4758
0.89
0.74
4.1
3.7
2.86
2.88
mmol/l
0.18
420
4507
12
76
1.59
0.72
2.4
2.1
8.71
120.50
ug/min
—
7
45
11
68
1.63
0.72
2.5
2.4
—
—
—
0
0
9
58
1.56
0.70
1.0
1.1
—
—
—
0
0
14
93
1.52
0.70
5.6
4.3
54.64
55.09
%
0.05
14
93
5
91
0.55
0.67
1.2
1.2
—
—
—
0
0
5
91
0.55
0.67
2.2
2.0
—
—
—
0
0
7
43
1.63
0.67
1.1
1.1
—
—
—
0
0
10
62
1.62
0.65
2.2
3.0
—
—
—
0
0
5
29
1.73
0.64
1.0
1.3
—
—
—
0
0
8
49
1.64
0.62
1.3
2.0
—
—
—
0
0
0
20
0.00
0.60
0.0
1.8
—
—
—
0
0
20
265
0.75
0.59
1.8
4.4
10.20
8.99
ug/l
—
9
209
0
22
0.00
0.59
0.0
1.8
—
—
—
0
0
6
37
1.63
0.55
1.2
2.4
21.66
21.23
ug/l
—
6
37
33
404
0.81
0.54
1.0
1.0
—
—
—
0
0
6
38
1.58
0.54
1.0
1.2
—
—
—
0
0
18
238
0.75
0.54
2.4
1.8
—
—
—
0
0
11
74
1.49
0.53
2.3
1.6
—
—
—
0
0
9
64
1.41
0.51
2.1
1.3
—
—
—
0
0
459
4459
1.10
0.49
4.2
3.3
5.85
5.68
mmol/l
1.66
415
4152
16
212
0.75
0.49
1.1
1.2
0.61
1.96
u/ml
1.14
11
142
170
1581
1.10
0.49
1.2
1.4
1.49
1.93
u/ml
0.26
37
384
421
4076
1.09
0.48
5.5
4.2
38.35
38.01
mmol/mol
0.26
383
3886
13
93
1.41
0.48
4.2
4.0
3.61
4.04
e9/l
0.36
13
93
7
46
1.53
0.48
1.1
1.1
208.00
252.13
mg/l
—
7
39
47
402
1.18
0.47
3.6
2.4
1020.02
3981.15
u/l
1.70
14
166
18
232
0.77
0.46
1.6
1.7
—
—
—
0
0
7
51
1.38
0.44
2.1
2.0
—
—
—
0
0
8
56
1.43
0.42
1.1
4.1
—
3.25
—
0
8
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
8
59
1.36
0.41
1.1
1.1
—
—
—
0
0
462
4728
0.92
0.39
3.9
3.5
4.62
4.71
mmol/l
1.09
424
4511
24
196
1.23
0.39
2.0
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
440
4506
0.93
0.37
3.5
3.2
1.37
1.26
mmol/l
1.39
399
4276
15
116
1.30
0.37
1.5
1.1
172.46
181.21
iu/ml
—
7
36
10
72
1.39
0.37
2.1
1.5
6600.40
17255.86
e6/l
—
5
51
9
71
1.27
0.36
1.3
1.7
—
—
—
0
0
13
99
1.32
0.35
1.1
1.1
—
—
—
0
0
9
122
0.73
0.35
2.0
1.5
—
—
—
0
0
15
189
0.79
0.34
1.5
1.3
—
—
—
0
0
97
896
1.10
0.34
2.6
3.5
10.15
2.20
ug/l
0.43
83
823
15
120
1.26
0.30
1.1
1.1
—
—
—
0
0
10
75
1.34
0.30
1.0
1.1
1.49
1.37
g/l
—
10
67
23
271
0.84
0.30
1.5
1.5
—
—
—
0
0
8
106
0.75
0.29
1.0
1.2
—
—
—
0
0
34
298
1.15
0.29
2.5
1.7
4.55
7.62
u/l
2.49
25
229
7
57
1.23
0.29
1.1
1.1
—
—
—
0
0
75
811
0.92
0.28
1.3
1.2
16.64
25.12
iu/ml
0.65
14
249
17
204
0.83
0.27
1.4
1.5
—
—
—
0
0
8
65
1.23
0.27
1.9
1.6
—
—
—
0
0
8
66
1.21
0.27
1.4
1.3
—
—
—
0
0
5
71
0.70
0.26
1.2
1.1
—
—
—
0
0
72
776
0.92
0.25
1.2
1.2
8.02
10.73
u/ml
0.15
22
321
22
189
1.17
0.24
2.1
1.6
190.15
207.39
u/ml
0.13
13
97
13
158
0.82
0.24
1.6
1.5
—
—
—
0
0
42
380
1.11
0.23
2.3
1.5
18.46
19.63
iu/l
0.08
32
305
7
95
0.73
0.22
1.4
1.2
—
—
—
0
0
5
42
1.19
0.21
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
14
165
0.85
0.19
1.4
2.1
—
—
—
0
0
615
6113
1.08
0.18
29.0
15.6
265.91
258.57
e9/l
1.89
599
5967
7
62
1.13
0.17
1.1
1.3
—
208.18
—
0
11
15
172
0.87
0.16
1.5
1.2
—
—
—
0
0
14
161
0.87
0.15
1.8
2.0
228.71
224.52
pmol/l
0.04
14
154
15
171
0.87
0.15
1.5
1.2
—
—
—
0
0
15
171
0.87
0.15
1.3
1.7
—
288.00
—
0
5
28
305
0.91
0.14
2.5
2.6
76.91
78.46
ml/min/173m2
0.04
11
117
615
6121
1.06
0.13
28.7
15.6
4.61
4.63
e12/l
0.31
598
5966
84
872
0.96
0.11
3.0
1.8
1.47
1.41
%
0.37
74
804
614
6115
1.05
0.10
28.9
15.8
40.62
41.62
%
0.67
554
5850
67
696
0.96
0.09
2.4
3.4
22.29
21.57
%
0.09
15
239
615
6127
1.05
0.09
29.1
15.8
135.67
137.83
g/l
2.73
610
6065
20
217
0.92
0.09
1.1
1.1
—
—
—
0
0
6
58
1.03
0.08
1.0
1.1
—
—
—
0
0
5
62
0.80
0.08
1.2
1.4
0.36
0.54
nmol/l
—
5
57
12
133
0.90
0.07
1.0
1.1
—
—
—
0
0
13
143
0.91
0.07
1.1
1.2
—
35.56
—
0
5
8
76
1.05
0.07
2.4
1.3
—
—
—
0
0
9
105
0.86
0.06
1.0
1.2
—
1.00
—
0
7
365
3670
0.99
0.04
4.4
3.3
48.64
38.53
u/l
1.67
343
3524
16
153
1.05
0.01
1.9
2.0
—
—
—
0
0
12
114
1.05
0.00
1.1
1.2
—
38.50
—
0
8
21
216
0.97
0.00
1.1
1.3
—
—
—
0
0
13
134
0.97
0.00
1.0
1.2
—
3.79
—
0
15
13
134
0.97
0.00
1.0
1.2
—
13.59
—
0
22
31
308
1.01
0.00
1.7
1.7
—
—
—
0
0
99
988
1.00
0.00
3.0
2.8
324.71
5369.14
umol/l
3.35
80
905
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
48
480
1.00
-0.00
2.4
2.3
12.91
13.59
nmol/l
0.20
40
449
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
54
0.93
-0.00
1.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
66
0.91
-0.00
1.0
2.5
0.00
0.00
g/l
—
6
66
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
424.40
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
16.52
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
87
0.92
-0.00
1.0
2.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint G6_CP and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_CP | 3.963 [3.08, 5.1] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.391 |
During the follow-up period (1.1.1998 — 31.12.2019), 237 out of 2065 females with G6_CP died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_CP | 4.157 [3.3, 5.24] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.01 |
During the follow-up period (1.1.1998 — 31.12.2019), 321 out of 2713 males with G6_CP died.
Mortality risk
Mortality risk for people of age
years, who have G6_CP.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.503% | 0.856% |
| 5 | 2.212% | 4.649% |
| 10 | 5.788% | 11.035% |
| 15 | 11.207% | 20.602% |
| 20 | 18.459% | 32.662% |
Relationships between endpoints
↥Index endpoint: G6_CP – Cerebral palsy
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data