Hair colour and hair shaft abnormalities

L12_HAIRCOLOUR

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L67 Hospital discharge: ICD-9 — 7042\|7043 Hospital discharge: ICD-8 — 7040[2-3]\|7040[7-9] Hospital discharge: excluded ICD-8 — 70708 Cause of death: ICD-10 — L67 Cause of death: ICD-9 — 7042\|7043 Cause of death: ICD-8 — 7040[2-3]\|7040[7-9] Cause of death: excluded ICD-8 — 70708 2 out of 7 registries used, show all original rules.	141
4. Check minimum number of events None	141
5. Include endpoints None	141
6. Filter based on genotype QC (FinnGen only)	141

Control definitions (FinnGen only)

Control exclude: L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: L60-L75
Name in latin: Abnormitates coloris et scapi pilorum

NAME	L12_HAIRCOLOUR
CONTROL_EXCLUDE	L12_DISORDSKINAPPENDIX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L67
HD_ICD_9	7042\|7043
HD_ICD_8	7040[2-3]\|7040[7-9]
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL	70708
COD_MAINONLY
COD_ICD_10	L67
COD_ICD_9	7042\|7043
COD_ICD_8	7040[2-3]\|7040[7-9]
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL	70708
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Hair colour and hair shaft abnormalities based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1104	455	638
Only index persons	890	379	511
Unadjusted period prevalence (%)
Whole population	0.02	0.01	0.02
Only index persons	0.02	0.01	0.02
Median age at first event (years)
Whole population	27.61	26.71	28.05
Only index persons	25.97	25.46	26.35

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	141	56	85
Unadjusted period prevalence (%)	0.03	0.02	0.04
Median age at first event (years)	27.03	24.63	28.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
130: Matched controls
1300

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

70403

ICD-8 Finland

Diseases of hair and hair follicles, Pili retenti (ingrown hair)

+∞

69.0

70409

ICD-8 Finland

Diseases of hair and hair follicles, Alii definiti et NUD

+∞

47.9

70402

ICD-8 Finland

Diseases of hair and hair follicles, Pili incarnati

+∞

9.5

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3038515) Glucose [Moles/volume] in Venous blood

8.27

12.12

6.7

4.0

9.3

8.5

mmol/l

0.31

(3008037) Lactate [Moles/volume] in Venous blood

7.92

11.69

6.7

3.9

1.6

mmol/l

0.17

(3041354) Potassium [Moles/volume] in Venous blood

7.37

7.26

4.4

3.3

4.0

4.1

mmol/l

0.25

(3035285) Chloride [Moles/volume] in Venous blood

7.37

7.26

4.4

3.3

104.8

105.4

mmol/l

0.14

(3033705) Calcium.ionized [Moles/volume] in Venous blood

7.37

7.26

4.4

3.3

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

3.63

5.53

11.1

3.5

51.8

51.7

0.01

(1761482) Bacteria [#/volume] in Urine by Culture

4.18

5.42

6.9

4.5

—

(3000330) Specific gravity of Urine by Test strip

3.17

4.54

6.7

3.6

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

257

2.17

4.20

1.8

1.7

411.9

436.4

pmol/l

0.36

219

(3021447) Carbon dioxide [Partial pressure] in Venous blood

114

2.57

4.08

9.0

3.9

5.8

kpa

0.10

109

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

2.98

3.93

3.6

2.7

1.6

1.3

0.38

(3012544) pH of Venous blood

118

2.48

3.80

9.0

3.9

—

(3023368) Bacteria identified in Blood by Culture

341

1.78

2.60

4.6

4.9

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

581

1.72

2.54

8.5

6.9

1.2

mmol/l

0.77

488

(3001122) Ferritin [Mass/volume] in Serum or Plasma

456

1.69

2.38

3.1

2.6

147.1

152.1

ug/l

0.06

409

(3025941) Bacteria identified in Stool by Culture

2.70

2.34

1.3

1.2

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

104

2.08

2.13

2.8

4.4

1.2

mmol/l

0.10

(42870588) Differential panel, method unspecified - Blood

397

1.63

2.04

5.0

5.4

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

208

1.77

2.01

3.2

3.1

0.7

2.2

e6/l

1.51

121

(3019198) Lymphocytes [#/volume] in Blood

584

1.56

1.84

7.0

5.6

1.7

1.9

e9/l

0.84

511

(21494890) Protein electrophoresis panel - 24 hour Urine

4.28

1.84

2.8

1.9

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

673

1.57

1.83

11.2

9.7

4.1

4.2

e9/l

0.14

586

(1761868) Lipid panel - Serum or Plasma

408

1.57

1.78

3.8

3.1

—

(3004775) Volume in Urine collected for unspecified duration

3.94

1.73

4.2

3.3

866.8

527.9

—

(3044290) Cell count panel - Cerebral spinal fluid

3.94

1.73

1.2

1.3

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

281

1.59

1.61

2.4

2.1

3.3

3.2

mg/l

0.12

237

(3013826) Glucose [Moles/volume] in Serum or Plasma

716

1.52

1.58

5.2

7.2

6.7

mmol/l

0.80

669

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

2.51

1.56

1.3

1.6

2.3

5.9

mg/l

—

(3001604) Monocytes [#/volume] in Blood

571

1.49

1.53

7.0

5.5

0.6

e9/l

0.10

486

(3006315) Basophils [#/volume] in Blood

574

1.48

1.47

7.0

5.5

0.0

e9/l

0.27

493

(3042936) Bacteria identified in Isolate by Culture

184

1.65

1.46

2.0

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

3.20

1.45

1.2

1.1

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

2.68

1.38

2.0

1.1

—

(3013115) Eosinophils [#/volume] in Blood

590

1.45

1.36

7.3

5.6

0.2

e9/l

1.98

521

(3019309) Folate [Moles/volume] in Red Blood Cells

232

1.55

1.31

1.8

1.7

972.5

1196.7

nmol/l

1.03

179

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

109

1.75

1.26

1.2

1.3

—

(3019230) Fractional oxyhemoglobin in Venous blood

2.46

1.25

2.7

2.2

59.2

64.5

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

2.69

1.22

3.0

1.1

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

2.69

1.22

3.0

1.1

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

219

1.53

1.21

3.2

2.8

1.0

0.9

e6/l

0.03

129

(3024928) Oxygen saturation in Venous blood

2.36

1.20

2.8

3.0

—

(3025159) Blasts/100 leukocytes in Blood

1.83

1.18

4.1

6.4

—

0.3

—

(3037522) Nuclear Ab [Titer] in Serum

144

1.63

1.17

1.5

1.4

240.0

644.4

titre

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

483

0.68

1.17

3.6

4.7

21.9

21.2

0.14

246

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

1.17

0.0

1.5

—

206.7

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

745

1.40

1.11

3.3

3.4

72.1

49.8

u/l

0.95

690

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

150

0.51

1.11

2.8

8.1

—

(40760892) CBC W Ordered Manual Differential panel - Blood

241

1.48

1.10

5.1

5.5

—

(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid

2.43

1.10

1.6

1.4

18.6

309.2

e6/l

—

(3016543) Leukocytes [#/volume] in Cerebral spinal fluid

2.43

1.10

1.2

1.0

2.9

e6/l

—

(3032080) INR in Blood by Coagulation assay

510

1.38

1.09

13.0

8.0

1.8

1.2

inr

—

150

(3044889) 12 lead EKG panel

871

0.72

1.08

3.8

4.2

—

(3002582) Erythrocytes [#/volume] in Urine

388

1.40

1.07

4.4

3.3

19.9

212.6

e6/l

0.61

300

(3017446) Testosterone [Moles/volume] in Serum or Plasma

106

0.45

1.06

1.0

2.4

16.9

13.1

nmol/l

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

2.11

1.04

1.0

1.1

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

2.11

1.04

1.0

1.7

—

(3023183) Ammonium ion [Moles/volume] in Plasma

2.32

1.04

1.2

3.7

37.8

35.4

umol/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

320

1.40

0.97

5.4

3.6

—

(3037756) Immunofixation for Serum or Plasma

2.27

0.94

1.8

1.2

—

(3013512) EKG study

401

1.34

0.86

5.9

4.0

—

(3044640) Blood type and Crossmatch panel - Blood

392

1.34

0.85

3.2

2.4

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

0.80

0.0

1.4

—

299.6

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.80

0.0

1.2

—

(3021589) Normoblasts [#/volume] in Blood

530

1.30

0.79

14.0

10.4

0.0

e9/l

0.49

431

(3018095) Leukocytes [#/volume] in Urine

434

1.31

0.79

5.3

3.9

219.3

62.5

e6/l

0.55

318

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.78

0.0

5.3

—

31.1

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.70

0.77

2.3

1.5

—

(40768443) Skin Pathology biopsy report

1.74

0.77

1.1

1.3

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.80

0.77

1.2

1.3

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

2.22

0.77

1.8

1.1

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

455

1.30

0.76

4.5

3.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

599

0.77

0.76

2.2

2.6

—

(3002179) Metamyelocytes/100 leukocytes in Blood

1.60

0.75

4.0

5.8

—

0.4

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

144

0.60

0.74

2.2

1.7

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

170

1.42

0.73

3.3

2.4

2.3

2.2

g/l

0.39

157

(3030467) Casts [#/volume] in Urine by Automated count

362

1.31

0.73

4.7

3.1

0.6

e6/l

0.01

270

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.70

0.69

1.4

1.5

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

256

0.70

0.69

4.3

3.7

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

244

1.35

0.69

1.5

1.8

0.6

1.4

mg/l

3.32

196

(3007853) Bacteria identified in Skin by Aerobe culture

138

1.44

0.67

1.6

—

(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

1.81

0.67

3.6

9.1

—

161.4

—

(3020779) Urea [Moles/volume] in Serum or Plasma

113

1.47

0.64

8.4

6.4

12.0

9.3

mmol/l

0.86

108

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.63

0.63

2.7

2.2

—

(3029937) Albumin [Presence] in Urine by Test strip

306

0.74

0.63

3.4

4.0

0.0

estimate

0.00

106

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

106

1.46

0.60

2.5

2.3

0.2

g/l

0.80

(3021788) Differential panel - Synovial fluid

0.00

0.60

0.0

1.2

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.54

0.59

2.9

1.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

575

1.24

0.59

5.0

4.3

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

206

1.32

0.56

2.0

3.7

0.8

mmol/l

0.48

192

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.56

0.56

1.2

1.3

—

(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma

1.48

0.54

2.3

3.7

5058.9

203.9

u/ml

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

605

0.83

0.48

4.1

5.4

2.1

2.6

ug/l

0.46

531

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.46

0.47

6.0

8.7

—

(3000963) Hemoglobin [Mass/volume] in Blood

124

1280

0.74

0.46

33.9

22.5

134.7

136.3

g/l

0.54

124

1261

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

126

0.69

0.46

1.3

1.6

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

117

1118

1.27

0.45

7.7

6.3

41.5

40.4

mmol/mol

0.51

111

1039

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.39

0.44

1.7

1.4

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

1.58

0.42

1.0

1.3

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

1.53

0.42

3.2

1.4

—

(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood

1.53

0.42

1.2

1.4

—

0.1

—

(40768795) Lymph node Pathology biopsy report

0.00

0.41

0.0

1.3

—

(4306422)

0.00

0.41

0.0

1.2

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.41

0.0

2.1

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.41

0.0

1.1

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

2.6

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.41

0.0

1.3

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.41

0.0

1.2

—

5.6

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

484

1.19

0.40

1.9

2.0

82.7

94.6

pmol/l

1.12

266

(3003694) ABO and Rh group [Type] in Blood

318

0.81

0.39

1.4

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

1.30

0.37

6.4

10.8

25.2

24.5

mmol/l

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

115

1191

0.81

0.36

5.4

5.5

2.6

2.7

mmol/l

0.71

108

1074

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

248

1.21

0.35

3.6

3.9

15.2

335.8

ng/l

1.47

197

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

108

1122

0.84

0.33

21.9

14.6

78.5

78.7

ml/min/173m2

0.03

921

(3018418) pH of Serum or Plasma

353

0.84

0.31

7.7

3.9

7.4

—

(3045414) Leukocytes [Presence] in Urine

1.31

0.31

1.4

1.6

—

(3049717) Cytology report of Urine Cyto stain

1.29

0.30

2.7

2.8

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

110

0.71

0.30

2.3

1.5

—

(3048689) Calprotectin [Mass/mass] in Stool

110

0.71

0.30

3.7

2.0

211.8

113.6

ug/g

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.34

0.29

1.4

1.6

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

116

0.76

0.28

2.2

1.6

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

506

1.14

0.28

4.7

4.0

25.3

47.0

ng/l

1.65

383

(3028026) IgM [Mass/volume] in Serum or Plasma

1.24

0.27

1.4

2.1

2.3

1.2

g/l

—

(3026008) Bacteria identified in Urine by Culture

332

1.16

0.27

4.8

2.9

—

(40761511) CBC panel - Blood by Automated count

118

1212

0.84

0.27

22.7

14.6

—

(3020682) Albumin/Creatinine [Ratio] in Urine

413

1.13

0.24

4.3

3.9

5.0

9.9

mg/mmol

1.26

258

(4094501)

1.36

0.24

1.0

1.1

—

(4010399)

0.76

0.23

1.4

1.3

—

(40761535) Cells panel - Urine sediment

0.75

0.23

3.1

3.2

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

1.26

0.22

6.6

3.1

17.5

40.4

mg/l

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

1.26

0.22

2.4

2.5

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

1.26

0.22

6.6

3.1

61.6

218.9

mg/l

—

(21494434) Karyotype in Bone marrow

0.00

0.21

0.0

1.1

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.21

0.0

1.5

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.3

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.3

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.4

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.3

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

2.2

—

20.1

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.0

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.0

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.21

0.0

1.1

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.21

0.0

1.3

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

155

0.82

0.21

4.1

3.5

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(3051014) Leukocytes [#/area] in Urine sediment by Automated count

0.00

0.21

0.0

1.6

—

4.2

—

(3017354) Segmented neutrophils/100 leukocytes in Blood

0.00

0.21

0.0

2.2

—

52.3

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

114

1169

0.87

0.21

4.9

4.8

4.4

4.6

mmol/l

0.81

107

1069

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.27

0.21

1.8

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.20

0.0

1.3

—

(4146454)

0.00

0.20

0.0

2.6

—

(4268621)

0.00

0.20

0.0

1.9

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.20

0.0

2.4

—

(3037467) Urinalysis macro (dipstick) panel - Urine

797

1.10

0.18

6.1

4.2

—

(3012516) Albumin [Mass/volume] in Urine

400

0.90

0.18

3.5

3.2

42.5

219.1

mg/l

0.54

257

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

1.18

0.18

2.3

2.0

2.5

3.0

ug/l

—

(3019150) Specific gravity of Urine by Refractometry

246

0.87

0.18

3.2

4.1

1.0

kg/l

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.24

0.17

1.2

2.4

10.6

9.2

g/l

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

0.73

0.17

1.8

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.15

0.16

8.9

3.2

4.2

4.4

pmol/l

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

551

1.09

0.16

6.7

6.0

1.2

mmol/l

0.83

496

(3009261) Glucose [Presence] in Urine by Test strip

581

1.09

0.15

5.2

3.8

0.0

estimate

—

104

(36304419) Bacteria [Presence] in Urine

344

1.10

0.15

4.6

3.0

—

(40761536) Microorganisms panel - Urine sediment

109

0.81

0.13

5.2

3.9

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

855

1.08

0.13

4.6

3.7

14.8

pmol/l

0.00

750

(40758558) Short blood count panel - Blood

299

1.09

0.12

7.8

6.4

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

114

1159

0.91

0.11

4.8

1.4

mmol/l

0.32

108

1051

(4035726)

115

1.14

0.11

1.2

1.4

—

(3002256) Pathology report gross observation

156

0.89

0.10

2.0

1.3

—

(3003396) Base excess in Arterial blood by calculation

154

1.12

0.10

4.6

7.8

2.1

1.0

mmol/l

0.66

130

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.14

0.10

1.0

2.1

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

401

1.07

0.09

2.8

3.7

2.3

mmol/l

0.07

351

(3035350) Ketones [Presence] in Urine by Test strip

560

1.06

0.09

5.3

3.8

0.0

estimate

0.00

106

(3022145) Colonoscopy Study observation

154

0.90

0.08

1.1

1.3

—

(3022313) Gas panel - Capillary blood

1.05

0.08

2.9

3.4

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.03

0.08

2.0

1.5

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

374

1.06

0.07

2.6

2.1

235.1

187.8

u/l

0.28

351

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

111

1125

0.94

0.07

4.6

4.3

1.3

mmol/l

0.07

105

1016

(3009343) pH of Capillary blood

1.02

0.07

3.1

3.3

—

7.4

—

(3000494) Fungus identified in Specimen by Culture

148

1.09

0.06

1.1

1.5

—

(3000991) Gas panel - Venous blood

109

1.11

0.06

14.3

9.2

—

(40768797) Stomach Pathology biopsy report

162

0.92

0.06

1.4

1.3

—

(3019225) pH of Specimen

119

1.10

0.06

2.8

4.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

151

0.92

0.05

1.1

1.3

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

139

0.93

0.03

2.3

2.0

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

106

1070

0.96

0.03

5.1

4.4

1.9

3.1

mu/l

0.54

953

(3019060) Gas panel - Arterial blood

1.09

0.03

2.0

4.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

199

0.95

0.03

1.9

2.1

—

(40768804) Tissue Pathology biopsy report

490

0.97

0.03

3.2

2.0

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

112

1.08

0.03

6.2

7.7

1.1

1.2

mmol/l

0.51

107

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

441

1.03

0.02

5.4

4.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

293

1.03

0.01

3.2

2.4

—

(3021601) Nitrite [Presence] in Urine by Test strip

573

1.02

0.01

9.2

5.2

0.0

estimate

0.00

112

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

146

0.95

0.00

2.2

2.1

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

196

1.02

0.00

1.4

1.2

25.2

45.4

iu/ml

—

(3009542) Hematocrit [Volume Fraction] of Blood

101

1008

1.01

0.00

28.6

16.5

38.0

39.3

0.39

683

(3000492) Spirometry study

103

0.97

0.00

1.5

1.4

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

115

1155

0.98

0.00

23.6

15.4

25.2

24.5

mg/l

0.09

104

913

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.0

1.8

—

13.2

—

(3000012) Reticulocyte production index

0.00

0.0

2.5

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.3

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

2.0

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

3.0

—

(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.3

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

0.0

1.0

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

0.0

1.6

—

(40758355) Pancreatic polypeptide [Moles/volume] in Serum or Plasma

0.00

0.0

2.8

—

56.6

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.0

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.6

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.0

2.0

—

(4015189)

0.00

0.0

3.7

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.6

—

(3022621) pH of Urine by Test strip

0.98

0.00

2.2

2.4

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

0.0

1.6

—

13.7

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.2

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

0.0

1.0

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

0.0

2.1

—

1.6

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

0.0

1.0

—

(4062490)

0.00

0.0

1.4

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

0.0

1.0

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.2

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

0.0

2.7

—

(3017704) Immunofixation for Urine

0.00

0.0

1.0

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

0.0

3.0

—

(40757494) Bilirubin.total [Moles/volume] in Blood

0.00

0.0

1.3

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.0

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.2

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.6

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.8

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.1

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.2

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

0.0

2.7

—

(3006576) Bicarbonate [Moles/volume] in Blood

0.00

0.0

4.6

—

25.5

—

(3004588) Protein electrophoresis panel - Serum or Plasma

0.99

0.00

3.1

1.5

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

0.0

2.5

—

800.8

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.6

—

(3016244) Insulin [Units/volume] in Serum or Plasma

0.00

0.0

1.9

—

11.3

—

(4133840)

0.00

0.0

1.2

—

(3028433) Virus identified in Specimen by Culture

0.00

0.0

1.3

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.5

—

(3012565) Volume of 24 hour Urine

0.00

0.0

2.0

—

2183.3

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

2.9

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.0

1.4

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.0

1.0

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

5.3

—

92.3

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.8

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

2.9

—

(3027923) C peptide [Moles/volume] in Serum or Plasma

0.00

0.0

2.4

—

1.2

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

2.0

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

0.0

1.1

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.4

—

(3050898) Methicillin resistant Staphylococcus aureus [Presence] in Genital specimen by Organism specific culture

0.00

0.0

2.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_HAIRCOLOUR and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_HAIRCOLOUR.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_HAIRCOLOUR – Hair colour and hair shaft abnormalities

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Hair colour and hair shaft abnormalities

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints