Hair colour and hair shaft abnormalities

L12_HAIRCOLOUR

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L67 Hospital discharge: ICD-9 — 7042\|7043 Hospital discharge: ICD-8 — 7040[2-3]\|7040[7-9] Hospital discharge: excluded ICD-8 — 70708 Cause of death: ICD-10 — L67 Cause of death: ICD-9 — 7042\|7043 Cause of death: ICD-8 — 7040[2-3]\|7040[7-9] Cause of death: excluded ICD-8 — 70708 2 out of 7 registries used, show all original rules.	141
4. Check minimum number of events None	141
5. Include endpoints None	141
6. Filter based on genotype QC (FinnGen only)	137

Control definitions (FinnGen only)

Control exclude: L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: L60-L75
Name in latin: Abnormitates coloris et scapi pilorum

NAME	L12_HAIRCOLOUR
CONTROL_EXCLUDE	L12_DISORDSKINAPPENDIX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L67
HD_ICD_9	7042\|7043
HD_ICD_8	7040[2-3]\|7040[7-9]
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL	70708
COD_MAINONLY
COD_ICD_10	L67
COD_ICD_9	7042\|7043
COD_ICD_8	7040[2-3]\|7040[7-9]
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL	70708
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Hair colour and hair shaft abnormalities based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1104	455	638
Only index persons	890	379	511
Unadjusted period prevalence (%)
Whole population	0.02	0.01	0.02
Only index persons	0.02	0.01	0.02
Median age at first event (years)
Whole population	27.61	26.71	28.05
Only index persons	25.97	25.46	26.35

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	137	56	81
Unadjusted period prevalence (%)	0.03	0.02	0.04
Median age at first event (years)	27.05	24.63	28.72

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
141: Matched controls
1410

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

70403

ICD-8 Finland

Diseases of hair and hair follicles, Pili retenti (ingrown hair)

+∞

73.5

70409

ICD-8 Finland

Diseases of hair and hair follicles, Alii definiti et NUD

+∞

52.4

70402

ICD-8 Finland

Diseases of hair and hair follicles, Pili incarnati

+∞

11.6

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3038515) Glucose [Moles/volume] in Venous blood

8.24

7.95

6.7

4.0

9.26

8.53

mmol/l

0.31

(3008037) Lactate [Moles/volume] in Venous blood

7.90

7.75

6.7

3.9

1.56

1.64

mmol/l

0.17

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

3.63

5.53

11.1

3.5

51.84

51.72

0.01

(3033705) Calcium.ionized [Moles/volume] in Venous blood

7.35

5.06

4.4

3.2

—

(3041354) Potassium [Moles/volume] in Venous blood

7.35

5.06

4.4

3.2

4.00

4.10

mmol/l

0.25

(3035285) Chloride [Moles/volume] in Venous blood

7.35

5.06

4.4

3.2

104.82

105.38

mmol/l

0.14

(3000330) Specific gravity of Urine by Test strip

3.17

4.54

6.7

3.6

—

(1761482) Bacteria [#/volume] in Urine by Culture

4.18

4.35

6.9

4.5

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

256

2.18

4.24

1.8

1.7

411.87

437.20

pmol/l

0.37

218

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

3.13

4.24

3.6

2.6

0.63

0.67

0.16

(3021447) Carbon dioxide [Partial pressure] in Venous blood

114

2.57

4.08

9.0

3.9

5.85

5.78

kpa

0.10

109

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

2.98

3.93

3.6

2.7

1.61

1.26

0.38

(3012544) pH of Venous blood

118

2.48

3.80

9.0

3.9

—

(3023368) Bacteria identified in Blood by Culture

340

1.78

2.63

4.6

4.9

—

(40760892) CBC W Ordered Manual Differential panel - Blood

540

1.73

2.61

6.1

6.4

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

581

1.72

2.54

8.5

6.9

1.20

1.21

mmol/l

0.76

494

(3025941) Bacteria identified in Stool by Culture

2.76

2.43

1.3

1.2

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

457

1.68

2.36

3.1

2.6

147.08

151.48

ug/l

0.05

411

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

102

2.12

2.24

2.8

4.4

1.22

mmol/l

0.07

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

208

1.77

2.01

3.2

3.1

0.68

2.21

e6/l

1.51

121

(21494890) Protein electrophoresis panel - 24 hour Urine

4.28

1.84

2.8

1.9

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

673

1.57

1.83

11.2

9.5

4.09

4.17

e9/l

0.14

586

(1761868) Lipid panel - Serum or Plasma

407

1.58

1.80

3.8

3.0

—

(3019198) Lymphocytes [#/volume] in Blood

586

1.55

1.80

7.0

5.5

1.68

1.87

e9/l

0.85

518

(3004775) Volume in Urine collected for unspecified duration

3.94

1.73

4.2

3.3

866.80

527.87

—

(3044290) Cell count panel - Cerebral spinal fluid

3.94

1.73

1.2

1.3

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

282

1.58

1.59

2.4

2.1

3.30

3.14

mg/l

0.13

238

(3013826) Glucose [Moles/volume] in Serum or Plasma

717

1.51

1.57

5.2

5.1

7.25

6.69

mmol/l

0.82

670

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

2.51

1.56

1.3

1.6

2.26

6.19

mg/l

—

(3042936) Bacteria identified in Isolate by Culture

182

1.67

1.52

2.0

—

(3006315) Basophils [#/volume] in Blood

573

1.48

1.49

7.0

5.5

0.04

e9/l

0.28

492

(3001604) Monocytes [#/volume] in Blood

573

1.48

1.49

7.0

5.4

0.58

0.59

e9/l

0.12

489

(3013115) Eosinophils [#/volume] in Blood

589

1.45

1.38

7.3

5.6

0.15

0.19

e9/l

1.98

520

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

3.01

1.37

1.2

1.1

—

(3019309) Folate [Moles/volume] in Red Blood Cells

231

1.56

1.34

1.8

1.7

972.46

1192.21

nmol/l

1.00

178

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

2.56

1.32

2.0

1.1

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

108

1.76

1.30

1.2

1.3

—

(3019230) Fractional oxyhemoglobin in Venous blood

2.46

1.25

2.7

2.2

59.17

64.47

—

(3022217) INR in Platelet poor plasma by Coagulation assay

597

1.42

1.25

11.7

13.1

1.68

1.24

inr

1.18

171

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

2.69

1.22

3.0

1.1

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

2.69

1.22

3.0

1.1

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

219

1.53

1.21

3.2

2.8

0.95

0.93

e6/l

0.03

129

(3024928) Oxygen saturation in Venous blood

2.36

1.20

2.8

—

(3025159) Blasts/100 leukocytes in Blood

1.83

1.18

4.1

6.4

—

0.33

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

1.17

0.0

1.5

—

207.12

—

(3037522) Nuclear Ab [Titer] in Serum

144

1.63

1.17

1.5

1.4

240.00

628.57

titre

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

483

0.68

1.17

3.6

4.7

21.87

21.34

0.10

246

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

150

0.51

1.11

2.8

8.1

—

(3027475) Erythrocytes [#/volume] in Cerebral spinal fluid

2.43

1.10

1.6

1.4

18.60

309.20

e6/l

—

(3016543) Leukocytes [#/volume] in Cerebral spinal fluid

2.43

1.10

1.2

1.00

2.86

e6/l

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

746

1.39

1.09

3.3

3.4

72.07

49.79

u/l

0.95

691

(3002582) Erythrocytes [#/volume] in Urine

387

1.41

1.09

4.4

3.3

19.87

213.29

e6/l

0.61

299

(3044889) 12 lead EKG panel

871

0.72

1.08

3.8

4.2

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

2.11

1.04

1.0

1.7

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

2.11

1.04

1.0

1.1

—

(3023183) Ammonium ion [Moles/volume] in Plasma

2.32

1.04

1.2

3.7

37.80

37.53

umol/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

320

1.40

0.97

5.4

3.6

—

(3037756) Immunofixation for Serum or Plasma

2.27

0.94

1.8

1.2

—

(40768443) Skin Pathology biopsy report

1.78

0.94

1.1

1.3

—

(3017446) Testosterone [Moles/volume] in Serum or Plasma

105

0.46

0.93

1.0

2.4

16.90

13.08

nmol/l

—

(3013512) EKG study

401

1.34

0.86

5.9

4.0

—

(3044640) Blood type and Crossmatch panel - Blood

393

1.34

0.83

3.2

2.4

—

(3018095) Leukocytes [#/volume] in Urine

432

1.32

0.82

5.3

3.9

219.32

62.90

e6/l

0.55

316

(3021589) Normoblasts [#/volume] in Blood

529

1.31

0.80

14.0

10.2

0.00

0.01

e9/l

0.49

430

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

0.80

0.0

1.4

—

299.55

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.80

0.0

1.2

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.78

0.0

5.3

—

31.09

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.70

0.77

2.3

1.5

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

454

1.31

0.77

4.5

3.2

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.80

0.77

1.2

1.3

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

2.22

0.77

1.8

1.1

—

(3030467) Casts [#/volume] in Urine by Automated count

361

1.32

0.75

4.7

3.1

0.58

e6/l

0.00

272

(3002179) Metamyelocytes/100 leukocytes in Blood

1.60

0.75

4.0

5.8

—

0.38

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

598

0.77

0.75

2.2

2.6

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

146

0.59

0.74

2.2

1.7

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

171

1.41

0.71

3.3

2.3

2.32

2.23

g/l

0.39

158

(3007853) Bacteria identified in Skin by Aerobe culture

136

1.46

0.71

1.6

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

244

1.35

0.69

1.5

1.8

0.59

1.44

mg/l

3.29

196

(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

1.88

0.69

3.6

9.4

—

161.40

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

255

0.71

0.68

4.3

3.7

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.66

0.68

1.4

1.5

—

(3020779) Urea [Moles/volume] in Serum or Plasma

113

1.47

0.64

8.4

6.3

11.97

9.34

mmol/l

0.86

107

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.63

0.63

2.7

2.2

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

105

1.48

0.63

2.5

2.2

0.19

0.22

g/l

0.77

(3029937) Albumin [Presence] in Urine by Test strip

306

0.74

0.63

3.4

4.0

0.00

estimate

-0.00

106

(3021788) Differential panel - Synovial fluid

0.00

0.60

0.0

1.2

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.54

0.59

2.9

1.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

576

1.24

0.58

3.2

2.7

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

205

1.33

0.58

2.0

3.7

0.78

0.81

mmol/l

0.54

192

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.56

0.56

1.2

1.3

—

(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma

1.51

0.55

2.3

3.7

5058.89

203.94

u/ml

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

605

0.83

0.48

4.1

5.3

2.06

2.65

ug/l

0.46

532

(3009542) Hematocrit [Volume Fraction] of Blood

124

1280

0.74

0.46

34.2

22.5

39.30

40.19

0.52

111

1199

(3000963) Hemoglobin [Mass/volume] in Blood

124

1280

0.74

0.46

33.9

22.4

134.70

136.30

g/l

0.52

124

1261

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

117

1118

1.27

0.45

7.5

6.2

41.49

40.42

mmol/mol

0.51

111

1040

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.39

0.44

1.7

1.4

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.44

0.44

6.0

8.7

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

1.58

0.42

1.0

1.3

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

1.53

0.42

3.2

1.4

—

(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood

1.53

0.42

1.2

1.4

—

0.10

—

(40768795) Lymph node Pathology biopsy report

0.00

0.41

0.0

1.3

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.41

0.0

1.3

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.41

0.0

1.1

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.41

0.0

2.1

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

2.6

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.41

0.0

1.2

—

5.63

—

(3014051) Protein [Presence] in Urine by Test strip

1.49

0.41

2.2

2.0

—

(3028626) Oxygen [Partial pressure] in Capillary blood

1.49

0.41

3.4

2.0

8.14

7.94

kpa

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

484

1.19

0.40

1.9

2.0

82.69

94.53

pmol/l

1.11

265

(3003694) ABO and Rh group [Type] in Blood

319

0.81

0.40

1.4

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

112

0.70

0.39

2.3

1.5

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

125

0.70

0.37

1.3

1.6

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

115

1191

0.81

0.36

5.4

5.5

2.57

2.68

mmol/l

0.73

108

1076

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

248

1.21

0.35

3.6

3.9

15.17

335.80

ng/l

1.47

197

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.36

0.31

1.4

1.6

—

(3026008) Bacteria identified in Urine by Culture

338

1.17

0.31

4.8

2.9

—

(3018418) pH of Serum or Plasma

352

0.85

0.30

7.7

3.9

7.40

—

(3045414) Leukocytes [Presence] in Urine

1.29

0.30

1.4

1.6

—

(3049717) Cytology report of Urine Cyto stain

1.29

0.30

2.7

2.8

—

(3048689) Calprotectin [Mass/mass] in Stool

110

0.71

0.30

3.8

2.0

211.75

114.24

ug/g

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

505

1.15

0.29

4.7

3.9

24.26

46.97

ng/l

1.78

383

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

118

0.75

0.28

2.2

1.6

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.24

0.27

1.4

2.1

2.31

1.15

g/l

—

(40761511) CBC panel - Blood by Automated count

118

1212

0.84

0.27

22.7

14.5

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

109

1126

0.86

0.27

21.8

14.6

78.54

78.78

ml/min/173m2

0.04

927

(3020682) Albumin/Creatinine [Ratio] in Urine

412

1.14

0.25

4.1

3.7

5.03

9.87

mg/mmol

1.27

258

(4094501) Cardiovascular stress test using bicycle ergometer

1.36

0.24

1.0

1.1

—

(4200892) Spirometry reversibility

0.76

0.23

1.4

1.3

—

(40761535) Cells panel - Urine sediment

0.75

0.23

3.1

3.2

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

1.29

0.23

6.6

3.1

61.62

218.92

mg/l

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

1.29

0.23

6.6

3.1

17.50

40.39

mg/l

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

1.26

0.22

2.4

2.5

—

(21494434) Karyotype in Bone marrow

0.00

0.21

0.0

1.1

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.21

0.0

1.1

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.3

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

168.77

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

2.2

—

20.13

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.3

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.4

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.21

0.0

1.3

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.3

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.0

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.0

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

155

0.82

0.21

4.1

3.4

—

(3051014) Leukocytes [#/area] in Urine sediment by Automated count

0.00

0.21

0.0

1.6

—

4.20

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

114

1169

0.87

0.21

4.9

4.8

4.42

4.56

mmol/l

0.83

107

1071

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.27

0.21

1.8

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

0.20

0.0

1.9

—

(4146454) Self-monitoring of blood glucose

0.00

0.20

0.0

2.6

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.20

0.0

1.3

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.20

0.0

2.4

—

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

1.18

0.18

2.3

2.0

2.47

3.03

ug/l

—

(3037467) Urinalysis macro (dipstick) panel - Urine

798

1.10

0.18

6.1

4.2

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.24

0.17

1.2

2.4

10.61

9.24

g/l

—

(3012516) Albumin [Mass/volume] in Urine

399

0.90

0.17

3.5

3.2

42.46

218.46

mg/l

0.54

258

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

0.73

0.17

1.8

—

(3019150) Specific gravity of Urine by Refractometry

245

0.88

0.17

3.2

4.1

1.01

1.02

kg/l

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.15

0.16

8.9

3.2

4.19

4.41

pmol/l

—

(36304419) Bacteria [Presence] in Urine

343

1.11

0.16

4.6

3.0

—

(3009261) Glucose [Presence] in Urine by Test strip

581

1.09

0.15

5.2

3.8

0.00

estimate

—

104

(40761536) Microorganisms panel - Urine sediment

109

0.81

0.13

5.2

3.8

—

(40758558) Short blood count panel - Blood

298

1.10

0.13

7.8

6.3

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

855

1.08

0.13

4.6

3.7

14.84

pmol/l

0.00

750

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

114

1159

0.91

0.11

4.8

1.41

1.44

mmol/l

0.34

108

1053

(3003396) Base excess in Arterial blood by calculation

154

1.12

0.10

4.6

7.9

2.12

0.99

mmol/l

0.65

133

(3015377) Calcium [Moles/volume] in Serum or Plasma

400

1.07

0.10

2.8

3.7

2.34

2.35

mmol/l

0.09

352

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.14

0.10

1.0

2.1

—

(4035726) Immunohistochemistry procedure

116

1.13

0.09

1.2

1.4

—

(3002256) Pathology report gross observation

155

0.89

0.09

2.0

1.3

—

(3022145) Colonoscopy Study observation

155

0.89

0.09

1.1

1.3

—

(40768797) Stomach Pathology biopsy report

164

0.90

0.08

1.4

1.3

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

373

1.06

0.08

2.6

2.0

235.13

188.07

u/l

0.28

350

(3022313) Gas panel - Capillary blood

1.05

0.08

2.9

3.4

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

111

1125

0.94

0.07

4.6

4.3

1.29

1.28

mmol/l

0.08

105

1017

(3035350) Ketones [Presence] in Urine by Test strip

563

1.05

0.07

5.3

3.8

0.00

estimate

-0.00

118

(3009343) pH of Capillary blood

1.02

0.07

3.1

3.3

—

7.41

—

(3000494) Fungus identified in Specimen by Culture

148

1.09

0.06

1.1

1.5

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

151

0.92

0.05

1.1

1.3

—

(3000991) Gas panel - Venous blood

110

1.10

0.05

14.2

9.2

—

(3019225) pH of Specimen

120

1.09

0.05

2.8

4.3

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

106

1072

0.95

0.04

5.1

4.4

1.86

3.10

mu/l

0.54

956

(3019060) Gas panel - Arterial blood

1.11

0.04

2.0

4.6

—

(40768804) Tissue Pathology biopsy report

492

0.96

0.04

3.2

2.0

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

440

1.03

0.03

5.4

4.0

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

138

0.94

0.02

2.3

2.0

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

198

0.95

0.02

1.9

2.1

—

(3000492) Spirometry study

107

0.93

0.02

1.5

1.4

—

(3021601) Nitrite [Presence] in Urine by Test strip

573

1.02

0.01

9.2

5.2

0.00

estimate

-0.00

112

(3015736) pH of Urine

442

0.99

0.00

6.0

3.5

—

5.90

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

197

1.02

0.00

1.4

1.2

25.19

44.11

iu/ml

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

295

1.02

0.00

3.2

2.4

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

145

0.96

0.00

2.2

2.1

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

115

1155

0.98

0.00

23.6

15.4

25.22

24.56

mg/l

0.08

104

912

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.02

0.00

2.0

1.5

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

-0.00

0.0

2.0

—

(3004588) Protein electrophoresis panel - Serum or Plasma

0.99

-0.00

3.1

1.5

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.5

—

800.75

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

3.2

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

-0.00

0.0

2.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.0

—

(3016244) Insulin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.9

—

11.29

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.4

—

(40758355) Pancreatic polypeptide [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.8

—

56.62

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

3.0

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.8

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.6

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

-0.00

0.0

1.1

—

(3002079) Sodium [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.0

—

177.37

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

-0.00

0.0

1.1

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

2.1

—

1.61

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3027923) C peptide [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.4

—

1.22

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

13.71

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

2.7

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

3.0

—

(3006576) Bicarbonate [Moles/volume] in Blood

0.00

-0.00

0.0

4.6

—

25.46

—

(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

3.2

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.8

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.4

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

-0.00

0.0

1.0

—

(3050898) Methicillin resistant Staphylococcus aureus [Presence] in Genital specimen by Organism specific culture

0.00

-0.00

0.0

2.2

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

2.7

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.9

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

3.0

—

(3012565) Volume of 24 hour Urine

0.00

-0.00

0.0

2.0

—

2183.33

—

(3045716) Anion gap in Serum or Plasma

0.00

-0.00

0.0

1.6

—

6.58

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.3

—

(40757494) Bilirubin.total [Moles/volume] in Blood

0.00

-0.00

0.0

1.3

—

(4062490) Immunoglobulin typing, IgG

0.00

-0.00

0.0

1.4

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.9

—

81.11

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.9

—

(3025130) Human papilloma virus identified in Specimen

0.00

-0.00

0.0

2.0

—

(3017704) Immunofixation for Urine

0.00

-0.00

0.0

1.0

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

-0.00

0.0

1.8

—

13.20

—

(3028433) Virus identified in Specimen by Culture

0.00

-0.00

0.0

1.3

—

(3022621) pH of Urine by Test strip

0.97

-0.00

2.2

2.4

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

3.0

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

5.1

—

82.67

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_HAIRCOLOUR and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_HAIRCOLOUR.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_HAIRCOLOUR – Hair colour and hair shaft abnormalities

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Hair colour and hair shaft abnormalities

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints