Benign neoplasm: Rectosigmoid junction

CD2_BENIGN_RECTOSIGMOID_JUNC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D12.7&
  • Cause of death: ICD-10 D12.7&

2 out of 7 registries used, show all original rules.

1409

4. Check minimum number of events

None

1409

5. Include endpoints

None

1409

6. Filter based on genotype QC (FinnGen only)

1409

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D12
Name in latin
Neoplasma benignum junctionis rectosigmoideae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7788 3752 4004
Only index persons 7330 3571 3759
Unadjusted period prevalence (%)
Whole population 0.11 0.11 0.11
Only index persons 0.14 0.13 0.14
Median age at first event (years)
Whole population 67.02 67.20 66.82
Only index persons 66.65 66.81 66.51

-FinnGen-

Key figures

All Female Male
Number of individuals 1409 681 728
Unadjusted period prevalence (%) 0.28 0.23 0.32
Median age at first event (years) 66.16 65.34 66.92

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1239
Matched controls
12392
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D12.7
ICD-10 Finland
Benign neoplasm: Rectosigmoid junction
4503599627370496.0
323.0
1238
*
UJF32
NOMESCO Finland
Coloscopy
10.8
312.5
893
2383
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
14.7
211.5
382
365
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
8.5
147.2
358
562
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
12.0
133.5
259
266
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
11.1
113.3
228
247
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
4.2
95.9
459
1521
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
6.7
79.7
220
386
UJF30
NOMESCO Finland
Ileoscopy through colon
5.2
77.0
270
634
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
8.9
58.9
131
163
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.8
58.2
539
2688
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
11.5
57.3
110
104
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
11.2
43.0
83
79
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
8.1
42.9
100
133
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
7.1
35.5
90
136
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
33.2
489
2864
A02BC02
ATC
pantoprazole; systemic
1.9
24.1
857
6706
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
21.3
361
2151
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
21.2
386
2361
JGA05
NOMESCO Finland
Endoscopic polypectomy in rectum
16.1
20.6
33
21
JFB47
NOMESCO Finland
Laparoscopic resection of sigmoid colon
9.0
20.4
43
49
D64.9
ICD-10 Finland
Anaemia, unspecified
2.5
20.4
181
808
D12.9
ICD-10 Finland
Benign neoplasm: Anus and anal canal
10.8
20.0
38
36
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.8
19.6
131
497
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.7
19.6
141
560
JN4BD
NOMESCO Finland
Extensive body CT
2.3
19.0
191
906
K63.5
ICD-10 Finland
Polyp of colon
7.1
18.0
44
64
P01AB01
ATC
metronidazole; oral, rectal
1.7
17.6
484
3348
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
4.4
16.9
62
147
D37.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Colon
5.8
16.7
47
83
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.8
16.5
108
402
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.5
16.4
132
558
D06
ICPC
Abdominal pain localized other
2.7
16.4
120
481
WX002
NOMESCO Finland
Sedation and analgesia
1.9
16.2
296
1785
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
3.1
15.9
90
305
K92.1
ICD-10 Finland
Melaena
2.9
15.6
95
340
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.2
15.5
164
793
N02BE01
ATC
paracetamol; systemic, rectal
1.9
15.4
1057
9343
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
15.3
593
4461
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
15.0
167
824
JFA45
NOMESCO Finland
Endoscopic contact coagulation in colon
11.5
14.8
27
24
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
13.8
286
1787
R4110
NOMESCO Finland
Physiotherapy
1.7
13.7
346
2294
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
13.6
225
1298
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.6
13.1
99
403
D37.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Rectum
7.0
12.4
30
44
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.6
12.0
87
347
UJH02
NOMESCO Finland
Anoscopy
2.9
11.9
73
263
S18
ICPC
Laceration/cut
1.5
11.8
534
4079
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
11.7
203
1190
N02AX02
ATC
tramadol; systemic, rectal
1.5
11.5
521
3974
R06.0
ICD-10 Finland
Dyspnoea
1.6
11.5
325
2209
K62.1
ICD-10 Finland
Rectal polyp
6.6
11.3
28
43
JF2BD
NOMESCO Finland
Extensive colon CT
5.5
11.2
32
59
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.6
11.1
84
342
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
11.1
268
1737
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.2
11.0
58
190
D01
ICPC
Abdominal pain/cramps general
2.1
11.0
124
617
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
10.9
353
2476
R03AC02
ATC
salbutamol; inhalant
1.5
10.9
582
4586
J01CA04
ATC
amoxicillin; systemic
1.5
10.5
898
7815
C18.70
ICD-10 Finland
Malignant tumor of the sigmoid without histology
5.3
10.5
31
60
R02
ICPC
Shortness of breath/dyspnoea
1.9
10.3
167
953
J01DA01
ATC
[U] cefalexin; systemic
1.5
10.2
718
5970
N03AX16
ATC
pregabalin; oral
1.6
9.8
289
1973
J01DB01
ATC
cefalexin; oral
1.5
9.7
954
8469
XF402
NOMESCO Finland
ECG with work load test
1.8
9.6
172
1013
A02BC05
ATC
esomeprazole; systemic
1.5
9.5
474
3652
L05
ICPC
Flank/axilla symptom/complaint
2.4
9.4
79
341
JFB31
NOMESCO Finland
Laparoscopic right hemicolectomy
4.7
9.2
30
65
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
3.6
9.1
40
115
J01AA02
ATC
doxycycline; systemic
1.5
9.1
919
8133
B01AB05
ATC
enoxaparin; parenteral
1.5
9.0
398
2974
M54.5
ICD-10 Finland
Low back pain
1.5
9.0
353
2569
JFB46
NOMESCO Finland
Resection of sigmoid colon
4.9
9.0
28
58
UJG02
NOMESCO Finland
Proctoscopy
3.4
8.7
40
119
J01MA12
ATC
levofloxacin; systemic
1.6
8.7
240
1604
R53
ICD-10 Finland
Malaise and fatigue
1.6
8.6
241
1619
WX704
NOMESCO Finland
Intubation
2.2
8.5
89
429
JFA85
NOMESCO Finland
Endoscopic mucosal or submucosal resection in colon
27.7
8.5
11
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
8.4
237
1592
B82
ICPC
Anaemia other/unspecified
3.2
8.2
41
131
UJF34
NOMESCO Finland
Left colonoscopy
6.5
8.2
20
31
SPAT1263
SPAT
Sampling
1.4
8.2
488
3862
C07AB07
ATC
bisoprolol; oral
1.4
8.1
612
5055
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
8.1
530
4263
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
3.2
8.1
40
127
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
8.1
256
1771
D18
ICPC
Change in faeces/bowel movements
3.4
8.1
37
111
K59.1
ICD-10 Finland
Functional diarrhoea
2.3
7.9
68
301
C18.72
ICD-10 Finland
Malignant tumor of sigmoid carcinoma of adenoma
8.5
7.8
16
19
WX110
NOMESCO Finland
Local anesthesy
1.4
7.8
740
6356
K85
ICPC
Elevated blood pressure
1.6
7.8
199
1301
WX290
NOMESCO Finland
Other blockade of nerve
1.4
7.7
406
3129
J01MA02
ATC
ciprofloxacin; systemic
1.4
7.7
464
3669
XF404
NOMESCO Finland
Ambulatory ECG
1.8
7.7
128
737
8140/3-C18.7
ICD-O-3
Adenocarcinoma, NOS, of sigmoid colon
4.0
7.7
29
74
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
3.8
7.7
31
84
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.5
7.6
57
235
T90
ICPC
Diabetes non-insulin dependent
1.5
7.6
298
2162
H02AB07
ATC
prednisone; oral
1.6
7.3
172
1102
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
7.2
401
3113
K80
ICPC
Cardiac arrhythmia NOS
2.0
7.2
92
483
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
7.1
228
1575
JGB04
NOMESCO Finland
Laparoscopic partial proctectomy with partial excision of mesorectum
12.1
7.1
12
10
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
6.9
137
833
UJD02
NOMESCO Finland
Gastroscopy
2.2
6.9
69
328
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.0
6.8
81
411
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.6
6.8
205
1397
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.7
6.8
44
167
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
6.8
205
1399
TJX00
NOMESCO Finland
Punkture or biopsy in gastrointestinal endoscopy
16.8
6.7
10
6
M79.6
ICD-10 Finland
Pain in limb
1.4
6.7
393
3069
K57.2
ICD-10 Finland
Diverticular disease of large intestine with perforation and abscess
3.0
6.7
35
117
UKC02
NOMESCO Finland
Cystoscopy
1.5
6.6
210
1446
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
6.6
206
1415
L03
ICPC
Low back symptom/complaint
1.5
6.6
261
1886
C05AA08
ATC
fluocortolone; rectal, topical
1.6
6.6
168
1095
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
6.6
312
2343
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
6.6
105
598
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.0
6.5
83
433
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.6
6.5
156
1005
H02AB06
ATC
prednisolone; systemic
1.4
6.4
545
4529
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.9
6.4
88
473
R03BB04
ATC
tiotropium bromide; inhalant
1.7
6.4
132
813
I50.9
ICD-10 Finland
Heart failure, unspecified
1.6
6.3
186
1260
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.6
6.3
177
1183
WX702
NOMESCO Finland
Supraglottic ventilation device
2.2
6.3
60
280
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
2.6
6.3
43
170
S17
ICPC
Abrasion/scratch/blister
3.2
6.3
31
100
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
6.3
154
997
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.8
6.2
102
588
N01
ICPC
Headache
1.9
6.2
83
445
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
6.2
94
525
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
6.2
133
831
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.5
6.2
47
196
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.9
6.1
88
484
I84.5
ICD-10 Finland
External hemorrhoids without complication
2.6
6.1
40
154
IAB01
NOMESCO Finland
Psychiatric pharmacotherapy consultation
12.6
6.1
10
8
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.2
6.0
55
252

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
533
1323
5.87
214.42
1.5
1.3
—
—
—
0
0
357
1435
2.99
63.46
4.7
4.1
10.1
22.3
ug/l
1.07
281
1189
719
4675
2.10
40.11
2.7
2.2
—
—
—
0
0
802
5469
2.08
38.90
6.0
6.1
2.8
2.9
%
0.32
746
5081
802
5490
2.07
38.24
6.2
6.3
9.0
8.9
%
0.58
756
5122
782
5320
2.06
37.74
6.0
6.0
0.7
0.7
%
0.10
729
4951
797
5489
2.04
36.82
5.9
6.0
58.4
58.0
%
0.37
741
5117
804
5583
2.02
35.96
6.2
6.2
26.5
26.7
%
0.20
748
5177
183
693
2.89
34.83
2.8
2.5
—
—
—
0
0
635
4092
2.00
34.73
5.5
5.8
—
—
—
0
0
337
1713
2.27
34.49
1.4
1.2
—
—
—
0
0
1153
9345
2.29
31.63
9.4
7.9
79.8
79.7
u/l
0.04
1111
8757
523
3249
1.97
30.86
2.7
2.2
3.4
3.1
mg/l
1.11
453
2741
880
6535
1.92
29.83
7.1
6.4
11.1
11.9
umol/l
1.57
836
6189
822
6021
1.88
28.49
6.1
6.0
0.2
0.2
e9/l
0.21
714
5238
802
5835
1.87
28.33
6.0
5.8
0.0
0.0
e9/l
0.77
692
4997
797
5814
1.85
27.63
6.1
5.8
0.6
0.6
e9/l
4.20
692
4966
807
5927
1.85
27.19
6.1
5.8
1.9
1.9
e9/l
0.15
696
5169
1082
8768
2.01
26.47
5.0
4.2
14.3
13.7
mm/h
0.57
1019
8041
849
6364
1.84
26.46
7.2
7.1
1.2
1.2
mmol/l
0.61
734
5351
679
4768
1.82
26.13
3.4
2.7
126.9
151.8
ug/l
1.75
638
4318
335
1870
2.04
26.09
2.6
2.5
2.4
2.3
g/l
1.75
315
1734
761
5571
1.80
25.10
5.7
4.9
35.0
34.9
g/l
0.12
712
5178
738
5359
1.79
24.97
2.3
2.1
95.4
94.2
pmol/l
0.26
387
2780
885
6811
1.80
24.29
9.4
9.2
4.3
4.2
e9/l
0.32
761
5943
315
1773
2.00
23.72
2.7
2.6
20.3
22.5
%
1.73
273
1510
573
3907
1.79
23.63
2.6
2.6
—
—
—
0
0
345
2020
1.94
23.09
2.6
2.5
11.9
12.6
umol/l
0.74
326
1861
256
1357
2.08
22.65
2.5
2.7
7.2
9.0
umol/l
1.27
216
1199
229
1166
2.15
22.50
2.0
2.2
131.1
144.2
ug/g
0.14
187
920
736
5446
1.74
22.38
10.1
10.7
1.3
1.3
inr
0.17
185
1524
565
3895
1.75
22.02
3.0
2.5
57.8
56.8
u/l
0.15
534
3576
775
5848
1.72
21.68
6.7
6.2
1.2
1.2
mmol/l
0.98
709
5264
473
3109
1.78
21.67
5.0
4.0
86.9
86.9
%
0.01
464
3040
1007
8193
1.80
21.43
5.0
4.6
—
—
—
0
0
917
7300
1.73
20.63
5.8
5.0
6.9
6.9
mmol/l
0.04
879
6891
1285
11432
2.41
20.05
22.7
16.4
25.1
26.0
mg/l
0.40
1121
9244
958
7956
1.64
16.04
5.4
4.8
177.3
2256.9
e6/l
1.97
12
130
435
3000
1.65
15.70
2.5
2.4
—
—
—
0
0
382
2559
1.68
15.38
3.0
2.8
519.5
548.8
mosm/kgh2o
1.94
311
2175
721
5641
1.57
15.16
4.3
4.2
—
—
—
0
0
317
2036
1.72
14.86
3.4
3.1
1.9
2.2
e6/l
0.21
188
1163
372
2516
1.65
14.27
4.7
4.0
502.7
362.9
ng/l
0.26
306
2097
522
3849
1.57
13.89
3.9
3.4
39.5
84.3
e6/l
1.59
409
3032
582
4399
1.55
13.86
4.4
3.8
59.4
107.1
e6/l
1.18
421
3247
1177
10455
1.76
13.82
5.5
4.8
1.9
2.1
mu/l
0.81
1094
9411
448
3192
1.59
13.81
1.6
1.6
20.1
20.6
nmol/l
0.29
378
2678
258
1594
1.76
13.79
3.0
2.6
1.8
1.8
%
0.07
226
1417
111
517
2.25
13.42
3.4
3.3
6187.4
7807.1
u/ml
0.08
90
444
196
1126
1.86
13.31
2.8
2.3
32.6
36.8
u/l
0.73
169
961
1133
10011
1.67
12.94
24.6
17.7
39.1
39.2
%
0.19
763
6490
552
4171
1.53
12.91
3.4
3.1
2130.0
1513.9
ng/l
1.14
484
3600
1004
8623
1.57
12.84
4.2
3.9
15.0
15.0
pmol/l
0.16
920
7721
565
4319
1.51
12.37
4.3
3.5
2.4
2.4
mmol/l
1.10
487
3732
1306
12091
2.10
12.06
26.3
19.4
139.7
139.6
mmol/l
0.13
1283
11784
195
1152
1.80
12.05
2.7
3.0
66.5
66.2
g/l
0.18
172
1045
153
838
1.93
11.99
3.7
3.9
7.4
7.4
ph
0.14
13
112
321
2174
1.62
11.97
3.3
2.8
1.0
1.2
e6/l
0.30
191
1298
412
2958
1.56
11.97
7.6
6.9
—
—
—
0
0
128
661
2.03
11.87
1.5
1.8
1.7
1.6
g/l
0.59
109
572
121
614
2.06
11.77
3.8
3.8
—
—
—
0
0
1307
12120
2.08
11.75
26.5
19.5
4.0
4.0
mmol/l
1.78
1285
11802
507
3820
1.51
11.74
4.9
4.2
7.4
7.4
ph
0.01
82
732
376
2661
1.56
11.58
1.9
1.8
998.5
1191.7
nmol/l
4.02
290
1981
310
2101
1.61
11.48
3.9
3.3
0.8
0.8
mmol/l
1.15
290
1961
359
2520
1.57
11.45
1.8
1.7
1.3
1.3
mg/l
0.04
290
1975
153
851
1.90
11.44
3.7
3.9
5.1
5.2
kpa
0.40
139
797
1310
12176
2.08
11.41
14.1
11.3
25.3
25.6
u/l
0.29
1277
11698
300
2021
1.62
11.38
1.5
1.5
2.6
2.6
g/l
0.11
166
1197
472
3535
1.50
11.11
3.8
3.2
0.4
0.5
e6/l
0.47
364
2738
104
512
2.11
10.96
3.5
4.2
24.5
25.1
mmol/l
1.24
91
478
225
1421
1.69
10.95
1.4
1.3
750.0
517.4
titre
0.61
44
320
167
972
1.81
10.80
2.2
2.8
—
—
—
0
0
455
3400
1.50
10.76
3.8
3.2
—
—
—
0
0
624
4965
1.46
10.73
4.6
4.0
55.8
51.1
ng/l
0.13
471
3740
1241
11376
1.76
10.73
5.8
5.0
6.2
6.1
mmol/l
1.53
1153
10212
202
1246
1.73
10.70
2.5
2.1
0.2
0.2
g/l
1.02
190
1161
172
1022
1.78
10.38
1.6
1.5
—
—
—
0
0
128
705
1.90
9.85
7.1
9.9
24.3
24.5
mmol/l
0.30
123
660
500
3862
1.46
9.80
4.9
4.2
—
—
—
0
0
268
1827
1.58
9.52
27.4
27.4
1.5
1.4
inr
0.55
40
238
503
3911
1.44
9.43
2.2
2.2
195.4
227.1
u/l
0.39
468
3670
480
3703
1.45
9.37
4.9
4.5
—
—
—
0
0
81
385
2.17
9.36
4.0
3.4
—
—
—
0
0
313
2224
1.52
9.20
1.3
1.2
3.2
1.6
u/ml
0.49
63
575
258
1762
1.57
9.06
6.4
5.6
1.0
1.0
mmol/l
0.05
245
1623
230
1532
1.60
8.98
1.2
1.3
—
—
—
0
0
369
2733
1.47
8.81
2.7
2.6
4.6
5.4
e6/l
0.65
315
2402
179
1129
1.67
8.68
1.4
1.4
—
—
—
0
0
525
4180
1.41
8.39
4.2
4.0
11.1
9.2
mg/mmol
0.37
349
2639
133
781
1.78
8.34
1.2
1.2
—
—
—
0
0
187
1206
1.63
8.30
7.7
7.2
10.5
10.6
mmol/l
0.12
176
1146
625
5140
1.39
8.19
11.7
10.4
0.0
0.0
e9/l
0.24
509
4204
14
23
6.14
8.19
1.0
1.1
—
—
—
0
0
1261
11777
1.67
8.05
20.4
15.8
—
—
—
0
0
498
3952
1.40
8.03
3.4
3.3
698.7
286.1
mg/l
0.80
324
2531
424
3276
1.42
7.95
2.9
2.9
4057.9
6809.6
umol/l
0.73
357
2794
262
1845
1.52
7.93
1.3
1.2
38.7
35.3
iu/ml
0.13
75
593
86
451
1.97
7.68
3.3
3.1
0.2
0.3
g/l
0.15
37
178
198
1319
1.58
7.68
3.8
4.6
—
—
—
0
0
1321
12529
1.87
7.58
33.5
24.1
7.0
6.8
e9/l
2.37
1291
12135
1320
12523
1.86
7.47
33.5
24.1
245.9
243.8
e9/l
0.51
1292
12171
1320
12524
1.85
7.46
33.4
24.0
91.4
91.6
fl
0.64
1299
12309
228
1578
1.53
7.45
6.6
7.5
0.8
1.2
mmol/l
0.84
188
1237
1320
12526
1.85
7.42
33.5
24.1
4.4
4.4
e12/l
1.87
1292
12135
1320
12528
1.85
7.39
33.7
24.2
132.0
134.0
g/l
4.61
1299
12310
502
4032
1.38
7.39
3.5
3.2
7.4
7.3
mmol/l
0.20
416
3347
227
1576
1.52
7.31
6.6
7.5
5.0
5.1
kpa
0.80
221
1506
1319
12524
1.83
7.25
33.3
24.0
30.3
30.4
pg
1.74
1300
12308
1183
10945
1.50
7.21
7.6
6.4
40.8
40.7
mmol/mol
0.12
1099
10022
226
1577
1.52
7.10
6.6
7.4
12.0
11.8
kpa
0.23
218
1509
486
3912
1.37
6.96
3.4
3.4
—
—
—
0
0
81
432
1.93
6.91
2.0
2.7
38.4
37.2
g/l
1.03
72
372
70
356
2.02
6.84
1.3
1.5
321.3
270.1
ug/g
1.19
41
220
73
382
1.96
6.59
1.5
1.6
—
—
—
0
0
166
1101
1.58
6.54
7.8
8.4
—
—
—
0
0
177
1198
1.55
6.38
2.7
2.7
72.0
69.3
e9/l
0.46
132
939
119
736
1.67
6.22
1.2
1.3
—
—
—
0
0
253
1854
1.44
6.17
1.9
2.1
—
—
—
0
0
171
1157
1.54
6.17
6.5
7.1
1.3
1.4
mmol/l
0.63
158
1115
118
730
1.67
6.16
7.3
10.1
—
—
—
0
0
1204
11262
1.47
6.12
5.2
4.7
1.4
1.5
mmol/l
1.37
1115
10179
1237
11634
1.52
6.12
5.9
5.3
2.6
2.6
mmol/l
0.65
1156
10541
177
1215
1.52
5.98
2.9
3.0
219.1
221.7
ng/l
0.03
164
1119
155
1035
1.56
5.93
3.9
3.7
93.2
94.3
ng/l
0.05
131
889
1211
11357
1.47
5.91
5.2
4.7
4.5
4.5
mmol/l
0.47
1116
10351
63
327
1.97
5.85
1.2
1.3
—
25.0
—
0
5
402
3227
1.34
5.64
1.7
1.7
1.4
1.4
mmol/l
0.34
345
2663
135
902
1.55
5.16
1.5
1.4
—
—
—
0
0
318
2496
1.35
5.11
4.2
3.1
2.5
2.5
mmol/l
0.77
276
2206
115
746
1.59
5.00
2.7
2.5
28.7
17.6
au/ml
—
5
27
195
1424
1.43
4.81
1.9
1.7
—
—
—
0
0
1160
10897
1.37
4.69
4.6
4.2
1.3
1.3
mmol/l
0.89
1058
9766
39
186
2.13
4.60
1.8
1.6
211.7
275.6
mu/l
1.98
34
169
96
611
1.61
4.54
5.0
3.8
24.6
24.1
mmol/l
0.78
88
549
54
292
1.88
4.52
4.2
3.3
151.1
1317.6
u/ml
0.74
47
274
103
670
1.58
4.45
3.6
3.8
—
—
—
0
0
930
8533
1.26
4.14
4.6
4.2
—
—
—
0
0
997
9225
1.28
4.13
29.7
20.1
14.1
13.9
%
3.07
986
9013
191
1442
1.38
3.89
1.4
1.4
—
—
—
0
0
108
739
1.50
3.75
7.2
7.9
25.2
24.9
mmol/l
0.41
108
734
52
296
1.79
3.75
3.1
2.7
—
—
—
0
0
226
1762
1.34
3.74
1.3
1.2
28.2
13.5
u/ml
1.13
64
637
30
141
2.15
3.72
3.1
3.4
—
—
—
0
0
15
50
3.02
3.69
3.7
2.5
—
—
—
0
0
164
1231
1.38
3.47
4.8
3.6
1.7
2.1
mmol/l
0.63
148
978
32
159
2.04
3.46
1.3
1.7
0.8
0.9
g/l
0.11
23
126
144
1059
1.40
3.44
2.1
2.1
392.8
373.2
nmol/l
0.59
130
967
44
245
1.82
3.43
1.6
1.3
56.6
59.0
mmol/l
0.17
33
202
87
583
1.52
3.36
1.3
1.2
—
—
—
0
0
33
168
1.99
3.35
1.2
1.2
—
—
—
0
0
21
90
2.35
3.25
1.2
1.3
7.2
7.5
g/l
0.08
16
65
21
90
2.35
3.25
1.2
1.3
0.3
0.4
g/l
0.36
16
65
48
280
1.74
3.22
2.1
2.3
123.6
127.9
g/l
0.51
29
213
111
789
1.44
3.21
3.6
3.1
4.3
4.1
e9/l
0.50
82
583
23
104
2.23
3.16
1.3
1.3
—
35.8
—
0
6
116
835
1.42
3.14
2.9
2.2
12.8
12.7
nmol/l
0.02
97
723
534
4714
1.21
3.06
5.9
5.3
2.0
3.0
ug/l
3.02
476
4183
54
331
1.66
3.05
1.3
1.7
—
—
—
0
0
102
722
1.44
3.03
1.9
1.9
1.5
1.5
g/l
0.04
97
664
123
901
1.40
3.03
2.7
2.9
10.9
10.8
g/l
0.02
117
826
162
1242
1.34
3.01
4.7
3.6
5.8
5.8
kpa
0.48
157
1204
57
356
1.63
3.00
4.0
5.0
—
—
—
0
0
21
94
2.25
2.97
1.2
1.3
—
—
—
0
0
30
157
1.93
2.86
2.5
2.6
—
—
—
0
0
63
410
1.56
2.81
2.1
2.0
21.2
21.7
s
0.51
57
369
30
160
1.89
2.72
1.5
1.5
—
—
—
0
0
19
85
2.25
2.71
3.5
3.6
—
—
—
0
0
34
190
1.81
2.68
1.5
1.2
11.6
10.3
u/l
0.14
23
149
131
992
1.35
2.66
1.7
1.5
—
—
—
0
0
77
531
1.48
2.65
2.0
1.9
—
—
—
0
0
632
5726
1.19
2.62
3.9
3.9
0.0
0.0
estimate
0.00
100
1089
15
61
2.47
2.62
3.0
2.1
15.5
17.2
nmol/l
0.41
15
55
86
610
1.44
2.57
1.1
1.2
112.9
144.2
iu/ml
0.30
30
237
47
292
1.63
2.56
2.4
2.2
—
—
—
0
0
12
44
2.74
2.55
2.2
2.5
—
—
—
0
0
82
578
1.44
2.53
2.3
2.8
—
—
—
0
0
30
165
1.84
2.50
1.2
1.1
—
—
—
0
0
82
580
1.44
2.49
3.7
5.3
1.7
1.6
%
0.55
82
546
70
480
1.48
2.49
3.1
4.0
60.6
66.6
mg/l
0.14
58
390
70
480
1.48
2.49
3.1
4.0
41.2
82.5
mg/l
0.83
58
392
7
16
4.39
2.47
1.7
1.5
—
—
—
0
0
123
934
1.35
2.47
4.3
4.8
—
—
—
0
0
21
103
2.05
2.42
1.2
1.2
379.9
362.9
nmol/l
0.09
13
86
47
300
1.59
2.32
1.2
1.1
101.7
95.4
titre
—
6
24
25
133
1.90
2.32
2.0
2.3
—
—
—
0
0
35
207
1.71
2.31
1.3
1.4
33.6
32.0
g/l
0.23
27
188
17
78
2.19
2.31
1.1
1.1
—
—
—
0
0
338
2924
1.21
2.30
1.3
1.3
—
—
—
0
0
134
1044
1.31
2.27
1.7
1.5
—
—
—
0
0
971
9185
1.18
2.26
30.5
21.6
330.9
331.7
g/l
2.23
963
9123
51
335
1.54
2.24
1.2
1.1
—
—
—
0
0
319
2753
1.21
2.22
3.6
3.8
—
—
—
0
0
26
143
1.83
2.19
1.1
1.2
—
—
—
0
0
151
1203
1.29
2.18
1.7
1.5
—
—
—
0
0
52
346
1.52
2.17
1.1
1.1
—
—
—
0
0
6
14
4.30
2.15
1.7
1.3
79.5
34.9
umol/l
—
6
14
79
573
1.40
2.13
3.5
5.3
0.9
0.9
%
0.62
79
540
18
88
2.06
2.11
1.2
1.3
—
—
—
0
0
22
118
1.88
2.02
1.5
2.1
—
1.1
—
0
5
81
597
1.38
2.00
3.0
3.1
4.4
4.4
pmol/l
0.06
70
514
85
632
1.37
1.99
3.5
2.4
0.7
0.7
%
0.24
85
608
104
802
1.32
1.93
3.5
3.0
—
—
—
0
0
15
71
2.12
1.92
1.2
1.8
—
—
—
0
0
629
5800
1.15
1.90
4.0
3.9
0.0
0.0
estimate
0.80
100
1062
44
292
1.52
1.89
3.9
2.7
32.6
33.2
umol/l
0.08
36
244
622
5739
1.15
1.85
5.5
5.2
0.0
0.0
estimate
0.00
103
1097
31
190
1.65
1.85
1.2
1.2
—
—
—
0
0
23
390
0.58
1.83
15.8
11.5
—
—
—
0
0
78
581
1.36
1.83
2.0
1.9
1.6
2.7
ug/l
0.46
70
511
27
160
1.70
1.82
1.1
1.2
—
0.5
—
0
13
15
73
2.07
1.81
1.1
1.2
—
—
—
0
0
6
18
3.34
1.74
2.0
1.1
—
—
—
0
0
29
178
1.64
1.73
2.7
2.7
—
—
—
0
0
71
526
1.37
1.73
1.2
1.2
—
—
—
0
0
22
125
1.77
1.72
1.2
1.2
—
—
—
0
0
26
156
1.68
1.69
1.3
1.4
—
—
—
0
0
23
134
1.73
1.66
4.3
1.4
—
—
—
0
0
23
134
1.73
1.66
4.3
1.4
—
—
—
0
0
37
244
1.53
1.66
1.3
1.6
—
—
—
0
0
43
293
1.48
1.66
4.1
3.4
7.1
7.7
mmol/l
1.57
43
285
128
1037
1.26
1.65
4.0
2.9
4.7
4.5
kpa
0.40
122
1001
281
3191
0.85
1.65
4.8
4.2
0.0
0.0
estimate
0.37
101
1046
22
127
1.74
1.64
1.2
1.1
—
—
—
0
0
23
136
1.70
1.59
4.3
1.4
—
—
—
0
0
23
136
1.70
1.59
4.3
1.4
—
—
—
0
0
40
273
1.48
1.55
1.4
1.2
—
—
—
0
0
24
145
1.67
1.54
1.2
1.4
6.9
6.6
mmol/l
0.16
18
137
50
357
1.42
1.54
4.3
3.4
24.6
24.9
mmol/l
0.17
43
310
23
138
1.68
1.52
1.2
1.2
—
—
nmol/l
—
0
0
7
27
2.60
1.51
1.9
1.4
—
—
—
0
0
307
2731
1.16
1.48
3.7
3.2
0.9
0.8
ug/l
0.58
236
1901
21
125
1.69
1.44
4.6
1.4
—
—
—
0
0
49
354
1.40
1.43
2.5
4.2
—
—
—
0
0
22
133
1.66
1.43
1.1
1.3
—
—
—
0
0
34
230
1.49
1.40
3.7
3.2
59.2
59.2
%
0.00
34
230
26
166
1.58
1.38
1.3
1.3
84594.5
105854.4
e6/l
0.13
11
102
224
2551
0.86
1.37
4.8
4.4
1.0
1.0
kg/l
0.60
38
388
19
112
1.71
1.35
3.5
3.4
22.9
33.1
mg/l
0.23
12
88
13
68
1.92
1.33
1.3
1.5
—
—
—
0
0
9
43
2.10
1.30
3.0
2.3
—
—
—
0
0
43
310
1.40
1.29
4.1
3.3
1.5
1.6
mmol/l
0.80
43
301
20
122
1.65
1.27
1.1
1.2
—
—
—
0
0
8
36
2.23
1.24
1.4
1.1
204.8
242.2
iu/ml
—
8
36
24
155
1.56
1.23
1.5
2.4
—
—
—
0
0
26
385
0.67
1.23
1.5
1.4
—
—
—
0
0
19
116
1.65
1.21
1.5
1.4
—
—
—
0
0
115
959
1.22
1.20
3.7
4.3
0.0
0.4
%
0.63
23
260
17
102
1.67
1.16
4.9
1.4
—
—
—
0
0
46
343
1.35
1.15
1.1
1.1
—
—
—
0
0
24
158
1.53
1.15
1.3
1.6
62.2
63.7
%
0.06
13
107
33
233
1.43
1.13
1.8
1.7
3.8
5.3
iu/l
—
9
67
22
143
1.55
1.11
1.3
1.2
2.3
4.8
u/ml
1.01
12
71
22
143
1.55
1.11
1.5
1.2
—
—
—
0
0
12
66
1.83
1.09
7.0
1.6
—
—
—
0
0
330
3600
0.89
1.07
3.8
3.1
—
—
—
0
0
312
2842
1.13
1.07
1.9
1.7
34252404.7
19180901.5
pmol/l
0.18
254
2294
141
1214
1.18
1.06
2.4
2.5
6.2
7.2
ug/l
0.50
115
1073
25
170
1.48
1.05
1.1
1.1
—
—
—
0
0
9
46
1.96
1.03
36.3
29.2
99.9
124.8
ug/l
—
9
39
19
122
1.56
1.02
1.5
1.5
—
—
—
0
0
9
47
1.92
1.02
1.7
2.2
—
—
—
0
0
43
325
1.33
1.01
1.9
2.1
10.6
12.0
mg/l
0.69
37
302
7
35
2.00
1.00
1.1
1.4
—
—
—
0
0
26
181
1.44
0.98
1.2
1.0
—
—
—
0
0
26
181
1.44
0.98
1.2
1.3
294.8
182.0
miu/ml
—
9
78
11
61
1.81
0.98
1.0
1.2
151.4
135.8
nmol/l
0.41
11
61
7
36
1.95
0.97
2.1
1.5
—
—
—
0
0
28
199
1.42
0.96
1.7
1.4
—
—
—
0
0
126
1087
1.17
0.95
5.1
3.8
1.2
1.2
mmol/l
0.26
111
940
6
27
2.23
0.93
1.0
1.3
—
183.0
—
0
6
12
70
1.72
0.92
1.2
1.7
—
—
—
0
0
20
134
1.50
0.92
1.3
1.2
—
—
—
0
0
78
647
1.22
0.90
1.3
1.4
—
—
—
0
0
30
219
1.38
0.90
3.9
3.0
4.9
4.5
e9/l
0.33
30
219
124
1075
1.17
0.89
3.7
4.2
0.7
0.9
%
0.40
27
329
117
1011
1.17
0.87
3.8
4.2
0.1
0.1
%
0.05
24
300
28
203
1.39
0.87
3.0
2.7
—
—
—
0
0
26
187
1.40
0.85
1.4
1.4
867.7
1749.6
e6/l
2.62
15
137
13
80
1.63
0.84
1.6
3.4
7.5
7.4
ph
—
6
27
6
31
1.94
0.84
1.7
2.1
—
—
—
0
0
8
45
1.78
0.84
1.5
2.2
—
—
—
0
0
27
197
1.38
0.82
1.3
1.3
31.7
32.5
iu/l
0.03
18
167
30
223
1.35
0.82
1.3
1.3
—
—
—
0
0
8
47
1.71
0.80
1.4
2.0
—
—
—
0
0
10
58
1.73
0.79
1.0
1.0
—
—
—
0
0
0
24
0.00
0.79
0.0
1.5
—
—
—
0
0
0
25
0.00
0.79
0.0
1.6
—
—
—
0
0
8
48
1.67
0.78
2.1
2.3
—
—
—
0
0
25
338
0.73
0.78
2.2
1.7
—
—
—
0
0
21
148
1.43
0.78
1.4
1.4
—
—
—
0
0
96
1109
0.86
0.76
3.6
3.5
—
—
—
0
0
43
537
0.79
0.76
7.4
4.5
—
—
—
0
0
41
324
1.27
0.75
1.6
1.5
0.2
0.2
g/l
0.87
36
305
34
262
1.31
0.75
3.9
3.1
—
—
—
0
0
28
210
1.34
0.74
5.9
3.0
—
—
—
0
0
111
971
1.16
0.74
3.7
4.0
0.4
0.6
%
0.91
22
239
16
108
1.49
0.73
1.4
1.4
18.1
29.8
%
—
9
70
21
150
1.41
0.73
1.1
1.1
—
15.8
—
0
7
7
39
1.80
0.72
27.3
16.1
1158.7
1656.6
nmol/l
—
7
39
37
292
1.27
0.70
4.4
4.2
—
—
—
0
0
5
27
1.85
0.68
5.8
4.5
—
—
—
0
0
5
27
1.85
0.68
10.8
6.7
—
—
—
0
0
5
27
1.85
0.68
1.4
1.4
—
—
—
0
0
18
127
1.42
0.68
1.4
1.5
—
—
—
0
0
40
321
1.25
0.67
1.2
1.2
—
—
—
0
0
26
197
1.33
0.66
1.1
1.5
—
—
—
0
0
258
2395
1.09
0.65
4.7
4.7
—
—
—
0
0
31
242
1.29
0.64
1.5
1.2
—
—
—
0
0
39
314
1.25
0.64
4.2
7.2
105.7
105.3
mmol/l
0.25
39
284
39
314
1.25
0.64
4.2
7.2
11.5
11.2
mmol/l
0.32
39
284
5
29
1.73
0.64
1.2
1.1
—
—
—
0
0
12
79
1.52
0.62
1.2
1.1
—
—
—
0
0
8
50
1.60
0.61
1.0
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
23
176
1.31
0.56
1.8
2.7
—
—
—
0
0
41
338
1.22
0.56
1.7
1.5
1.1
1.2
g/l
0.30
35
321
6
38
1.58
0.54
2.2
1.8
—
—
—
0
0
6
38
1.58
0.54
1.0
1.1
237.3
251.3
pmol/l
—
6
24
9
60
1.50
0.54
1.0
1.1
—
—
—
0
0
9
60
1.50
0.54
1.0
1.0
—
—
—
0
0
13
91
1.43
0.53
1.5
1.2
—
—
—
0
0
13
91
1.43
0.53
6.5
1.9
—
—
—
0
0
24
188
1.28
0.51
1.3
1.4
—
—
—
0
0
9
65
1.39
0.50
1.9
2.9
1715.6
1896.7
ml
—
9
57
123
1117
1.11
0.50
1.5
1.6
—
—
—
0
0
10
144
0.69
0.49
2.1
1.6
—
—
—
0
0
10
144
0.69
0.49
2.1
1.6
—
—
—
0
0
10
144
0.69
0.49
2.1
1.6
—
—
—
0
0
10
144
0.69
0.49
2.1
1.6
—
—
—
0
0
7
45
1.56
0.49
1.4
1.3
—
—
—
0
0
7
46
1.52
0.48
1.0
1.3
—
—
—
0
0
40
336
1.20
0.48
3.1
3.2
0.8
0.8
nmol/l
0.12
30
263
35
417
0.84
0.45
1.8
1.5
—
—
—
0
0
55
480
1.15
0.43
3.0
2.2
222.0
482.3
ug/l
1.40
55
453
5
31
1.62
0.43
1.0
1.0
—
—
—
0
0
68
604
1.13
0.42
1.3
1.2
141.6
188.3
u/ml
0.65
63
551
5
34
1.47
0.40
1.0
1.2
77.3
69.4
mu/l
—
5
24
5
35
1.43
0.39
2.2
1.7
—
—
—
0
0
15
115
1.31
0.39
1.0
1.1
—
—
—
0
0
39
335
1.17
0.38
1.4
1.7
8549.9
16736.8
e6/l
1.33
28
252
11
81
1.36
0.36
1.5
1.2
—
—
—
0
0
29
246
1.18
0.34
1.4
1.6
—
—
—
0
0
12
91
1.32
0.33
1.8
1.2
—
—
—
0
0
6
45
1.33
0.33
1.2
1.4
13.2
15.2
g/l
—
6
34
58
520
1.12
0.33
1.3
1.3
—
—
—
0
0
313
3007
1.05
0.33
3.8
3.7
—
—
—
0
0
10
74
1.35
0.32
2.1
1.5
1.1
1.0
g/l
—
10
74
13
101
1.29
0.31
2.5
2.3
—
—
—
0
0
14
110
1.28
0.31
1.4
1.2
—
—
—
0
0
34
296
1.15
0.30
1.1
1.1
—
—
—
0
0
13
103
1.26
0.28
2.2
1.8
2.0
2.4
u/field
—
6
42
10
76
1.32
0.28
1.4
1.4
2.2
1.0
promille
—
10
61
26
225
1.16
0.26
1.7
2.0
2.0
1.6
mmol/l
0.48
26
220
30
264
1.14
0.24
1.4
1.4
202.9
666.7
e6/l
0.56
24
215
30
264
1.14
0.24
1.3
1.3
3.8
42.3
e6/l
1.02
21
207
17
142
1.20
0.24
1.4
1.2
—
—
—
0
0
16
133
1.21
0.24
1.3
1.3
28908.5
93201.4
e6/l
—
10
93
5
38
1.32
0.23
1.0
1.1
1197.8
1599.2
miu/ml
—
5
38
10
124
0.81
0.21
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
44.6
—
0
5
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
32
287
1.12
0.21
2.9
2.7
15.8
15.9
%
0.07
19
149
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
48
1.25
0.20
6.2
2.9
—
—
—
0
0
13
110
1.18
0.17
1.2
1.2
1.3
1.4
nmol/l
0.05
13
94
5
67
0.75
0.17
1.0
1.4
0.7
1.1
nmol/l
—
5
50
8
71
1.13
0.16
1.0
1.1
—
—
—
0
0
8
72
1.11
0.16
5.4
14.5
—
—
—
0
0
8
73
1.10
0.15
1.8
1.8
—
—
—
0
0
9
81
1.11
0.15
2.4
2.2
—
—
—
0
0
7
86
0.81
0.14
1.6
2.7
—
—
—
0
0
56
593
0.94
0.14
1.2
1.4
—
—
—
0
0
12
104
1.16
0.12
1.8
1.7
12.0
10.8
%
0.45
12
104
106
1025
1.04
0.11
4.2
4.0
—
—
—
0
0
29
269
1.08
0.11
1.3
1.3
—
—
—
0
0
6
54
1.11
0.09
6.2
2.7
—
—
—
0
0
31
293
1.06
0.08
5.6
5.1
3.2
2.8
mmol/l
0.39
25
203
11
98
1.12
0.07
1.5
1.2
—
—
—
0
0
6
74
0.81
0.07
1.0
1.5
—
—
—
0
0
8
78
1.03
0.07
1.1
1.2
47.6
38.3
mg/l
—
8
69
7
84
0.83
0.07
2.4
2.6
—
—
—
0
0
9
87
1.03
0.07
1.0
1.8
—
—
—
0
0
35
336
1.04
0.05
2.3
2.4
320.3
92.0
ug/min
0.79
23
203
11
100
1.10
0.05
1.0
1.0
0.9
4.4
u/ml
—
6
41
23
219
1.05
0.04
1.7
1.8
—
—
—
0
0
15
159
0.94
0.03
6.7
4.4
—
—
—
0
0
27
263
1.03
0.01
4.8
3.7
31.8
26.9
mg/l
0.18
17
171
36
356
1.01
0.00
5.9
4.7
7.4
7.4
ph
0.82
31
289
11
109
1.01
0.00
1.2
1.1
—
—
—
0
0
18
181
0.99
0.00
1.6
1.2
356.9
308.4
u/ml
0.25
13
98
16
157
1.02
0.00
1.4
1.3
—
—
—
0
0
23
225
1.02
0.00
1.3
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
397.5
—
0
8
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
0.00
5.6
6.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
9
89
1.01
0.00
1.2
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
11
110
1.00
0.00
1.2
1.1
—
—
—
0
0
9
91
0.99
0.00
2.4
2.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
2.9
—
0
5
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
7
76
0.92
0.00
1.1
1.1
241.4
249.1
mg/l
—
7
68
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
7
75
0.93
0.00
1.1
2.9
—
—
—
0
0
5
50
1.00
0.00
2.6
2.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_RECTOSIGMOID_JUNC and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_RECTOSIGMOID_JUNC 1.169 [1.03, 1.32] 0.013
Birth year 0.997 [0.99, 1.01] 0.425

During the follow-up period (1.1.1998 — 31.12.2019), 680 out of 3167 females with CD2_BENIGN_RECTOSIGMOID_JUNC died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_RECTOSIGMOID_JUNC 1.224 [1.08, 1.39] 0.001
Birth year 0.986 [0.97, 1.0] 0.02

During the follow-up period (1.1.1998 — 31.12.2019), 919 out of 3357 males with CD2_BENIGN_RECTOSIGMOID_JUNC died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_RECTOSIGMOID_JUNC.

N-year risk Females Males
1 0.101% 0.256%
5 0.705% 1.504%
10 1.808% 3.471%
15 3.541% 6.366%
20 6.085% 10.725%

Relationships between endpoints

Index endpoint: CD2_BENIGN_RECTOSIGMOID_JUNC – Benign neoplasm: Rectosigmoid junction

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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