Benign neoplasm: Rectosigmoid junction

CD2_BENIGN_RECTOSIGMOID_JUNC

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D12.7&
  • Cause of death: ICD-10 D12.7&

2 out of 7 registries used, show all original rules.

1516

4. Check minimum number of events

None

1516

5. Include endpoints

None

1516

6. Filter based on genotype QC (FinnGen only)

1462

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D12
Name in latin
Neoplasma benignum junctionis rectosigmoideae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7788 3752 4004
Only index persons 7330 3571 3759
Unadjusted period prevalence (%)
Whole population 0.11 0.11 0.11
Only index persons 0.14 0.13 0.14
Median age at first event (years)
Whole population 67.02 67.20 66.82
Only index persons 66.65 66.81 66.51

-FinnGen-

Key figures

All Female Male
Number of individuals 1462 699 763
Unadjusted period prevalence (%) 0.30 0.25 0.35
Median age at first event (years) 66.43 65.62 67.17

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1516
Matched controls
15160
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D12.7
ICD-10 Finland
Benign neoplasm: Rectosigmoid junction
4503599627370496.0
307.7
1513
5
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
13.6
307.7
509
542
UJF32
NOMESCO Finland
Coloscopy
10.2
307.7
1086
3014
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
7.9
262.9
438
742
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
10.5
260.8
320
375
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
10.0
225.5
284
342
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
6.9
164.1
285
491
UJF30
NOMESCO Finland
Ileoscopy through colon
4.9
136.7
362
910
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
3.7
124.2
574
2147
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
10.3
112.2
130
137
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
7.0
106.0
172
272
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
9.0
88.1
112
133
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
7.6
86.6
128
182
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
7.1
85.3
135
207
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
74.0
665
3430
K63.5
ICD-10 Finland
Polyp of colon
6.4
49.4
84
138
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
42.6
608
3622
JGA05
NOMESCO Finland
Endoscopic polypectomy in rectum
12.6
37.6
37
30
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
36.4
499
2892
D12.9
ICD-10 Finland
Benign neoplasm: Anus and anal canal
9.0
33.8
42
48
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.8
33.8
181
691
JFB47
NOMESCO Finland
Laparoscopic resection of sigmoid colon
6.9
32.8
51
76
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.1
29.4
128
434
JF2BD
NOMESCO Finland
Extensive colon CT
8.6
28.8
37
44
D37.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Colon
5.3
27.0
55
107
D37.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Rectum
7.6
26.8
38
51
JFA45
NOMESCO Finland
Endoscopic contact coagulation in colon
10.2
26.5
30
30
JN4BD
NOMESCO Finland
Extensive body CT
2.3
26.1
228
1092
A02BC02
ATC
pantoprazole; systemic
1.9
25.6
1095
8814
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
25.5
450
2783
D64.9
ICD-10 Finland
Anaemia, unspecified
2.2
25.5
232
1130
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.5
24.3
173
756
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.8
24.2
133
512
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.2
22.7
205
993
K92.1
ICD-10 Finland
Melaena
2.7
22.7
125
482
D06
ICPC
Abdominal pain localized other
2.5
22.6
154
659
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.5
22.1
152
653
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
3.8
22.1
69
189
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
21.8
194
934
R02
ICPC
Shortness of breath/dyspnoea
2.0
19.9
238
1280
WX002
NOMESCO Finland
Sedation and analgesia
1.8
19.6
347
2123
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.7
19.6
108
416
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
19.6
303
1778
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
2.8
19.1
99
370
Z2221
NOMESCO Finland
Medical doctor
1.7
19.0
427
2799
P01AB01
ATC
metronidazole; oral, rectal
1.7
18.8
596
4274
R4110
NOMESCO Finland
Physiotherapy
1.7
18.6
454
3041
K62.1
ICD-10 Finland
Rectal polyp
5.6
18.4
35
64
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
17.6
773
5976
UJH02
NOMESCO Finland
Anoscopy
2.8
17.5
87
318
D01
ICPC
Abdominal pain/cramps general
2.1
17.4
178
902
C18.70
ICD-10 Finland
Malignant tumor of the sigmoid without histology
4.8
17.3
39
83
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.1
16.7
72
243
B01AB05
ATC
enoxaparin; parenteral
1.6
16.5
524
3731
ZXE00
NOMESCO Finland
One hour or less
1.6
16.5
587
4297
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
15.8
362
2368
8140/3-C18.7
ICD-O-3
Adenocarcinoma, NOS, of sigmoid colon
4.5
15.5
37
83
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
4.3
15.4
40
96
Z12.1
ICD-10 Finland
Special screening examination for neoplasm of intestinal tract
5.0
15.0
32
65
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
14.8
465
3287
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.1
14.6
143
712
XF402
NOMESCO Finland
ECG with work load test
1.9
14.5
202
1138
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
14.3
271
1677
J01DB01
ATC
cefalexin; oral
1.7
14.1
1201
10559
UJG02
NOMESCO Finland
Proctoscopy
3.4
13.9
49
146
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
13.7
349
2336
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
3.5
13.6
47
138
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
13.6
578
4356
JFB31
NOMESCO Finland
Laparoscopic right hemicolectomy
4.0
13.5
38
97
JFA52
NOMESCO Finland
Other endoscopic haemostatic procedure in colon
11.6
13.3
24
21
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
3.1
12.9
53
174
N02BE01
ATC
paracetamol; systemic, rectal
1.8
12.9
1336
12168
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
12.9
296
1927
WX704
NOMESCO Finland
Intubation
2.1
12.5
126
634
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
12.3
552
4185
C18.72
ICD-10 Finland
Malignant tumor of sigmoid carcinoma of adenoma
9.7
12.2
24
25
N03AX16
ATC
[U] pregabalin
1.6
11.9
363
2526
WX402
NOMESCO Finland
General anaesthesia
1.6
11.8
297
1974
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
11.7
189
1113
JFB46
NOMESCO Finland
Resection of sigmoid colon
4.1
11.6
31
76
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.5
11.6
73
301
R06.0
ICD-10 Finland
Dyspnoea
1.5
11.6
429
3117
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
11.5
190
1128
A02BC05
ATC
esomeprazole; systemic
1.5
11.2
599
4680
R03AC02
ATC
salbutamol; inhalant
1.4
11.1
757
6189
L05
ICPC
Flank/axilla symptom/complaint
2.1
11.1
106
523
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.8
11.1
56
207
N02AX02
ATC
tramadol; systemic, rectal
1.4
11.0
660
5263
JFA85
NOMESCO Finland
Endoscopic mucosal or submucosal resection in colon
13.0
10.7
18
14
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
10.6
376
2698
JN3AD
NOMESCO Finland
Abdominal CT examination
1.8
10.6
179
1069
J01MA12
ATC
levofloxacin; systemic
1.6
10.5
295
2007
B82
ICPC
Anaemia other/unspecified
2.7
10.4
55
208
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
10.4
971
8369
Z3226
NOMESCO Finland
Physiotherapist
1.6
10.3
274
1842
K57.2
ICD-10 Finland
Diverticular disease of large intestine with perforation and abscess
3.2
10.2
40
128
J01CA04
ATC
amoxicillin; systemic
1.5
10.1
1130
10049
D16
ICPC
Rectal bleeding
2.9
10.0
46
162
D18
ICPC
Change in faeces/bowel movements
2.9
10.0
46
162
JGA85
NOMESCO Finland
Endoscopic mucosal or submucosal resection in rectum
20.2
9.8
14
7
K59.1
ICD-10 Finland
Functional diarrhoea
2.1
9.8
87
418
R53
ICD-10 Finland
Malaise and fatigue
1.5
9.7
333
2367
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
2.5
9.6
59
241
A01
ICPC
Pain general/multiple sites
1.8
9.5
141
808
UJF34
NOMESCO Finland
Left colonoscopy
7.2
9.5
22
31
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.0
9.4
107
562
JN4AD
NOMESCO Finland
Body CT examination
1.7
9.3
169
1029
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
2.9
9.3
43
152
K59.09
ICD-10 Finland
Constipation, unspecified
1.9
9.3
114
616
J01AA02
ATC
doxycycline; systemic
1.5
9.2
1136
10176
WX290
NOMESCO Finland
Other blockage of nerve
1.4
9.2
546
4309
K85
ICPC
Elevated blood pressure
1.6
9.2
264
1804
S18
ICPC
Laceration/cut
1.4
9.1
687
5647
L03
ICPC
Low back symptom/complaint
1.5
9.0
371
2731
H02AB06
ATC
prednisolone; systemic
1.4
9.0
688
5665
SPAT1263
SPAT
Sampling
1.4
8.9
581
4652
JGB04
NOMESCO Finland
Laparoscopic partial proctectomy with partial excision of mesorectum
12.6
8.9
15
12
H02AB07
ATC
prednisone; oral
1.6
8.8
205
1332
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.7
8.8
167
1030
C05AA08
ATC
fluocortolone; rectal, topical
1.6
8.8
202
1309
WX702
NOMESCO Finland
Supraglottic ventilation device
2.1
8.7
84
417
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
8.6
260
1794
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.9
8.6
100
531
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
8.5
196
1270
L01BC06
ATC
capecitabine; oral
2.2
8.5
69
320
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
4.5
8.4
20
45
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.0
8.4
84
423
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.0
8.3
87
444
C07AB07
ATC
bisoprolol; oral
1.4
8.2
784
6655
JFF23
NOMESCO Finland
Transversostomy
3.7
8.2
25
68
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
8.2
682
5664
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
8.1
486
3823
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.9
8.1
103
564
UJD02
NOMESCO Finland
Gastroscopy
2.1
8.0
78
388
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.7
8.0
167
1054
C19
ICD-10 Finland
Malignant neoplasm of rectosigmoid junction
6.3
8.0
20
32
T90
ICPC
Diabetes non-insulin dependent
1.4
7.9
379
2862
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
7.9
190
1242
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
7.9
285
2039
Z3231
NOMESCO Finland
Registered nurse
1.4
7.9
388
2945
A02BA02
ATC
ranitidine; systemic
1.5
7.9
295
2126
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
7.9
136
816
G47.3
ICD-10 Finland
Sleep apnoea
1.5
7.9
318
2327
R39.1
ICD-10 Finland
Other difficulties with micturition
2.4
7.8
51
215
L17
ICPC
Foot/toe symptom/complaint
1.4
7.8
405
3103
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.1
7.8
73
358
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
7.8
365
2745
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.7
7.8
147
904
ZX120
NOMESCO Finland
Intravenous
1.7
7.8
143
873
K29.7
ICD-10 Finland
Gastritis, unspecified
2.3
7.8
56
247
TJG20
NOMESCO Finland
Transanal irrigation
15.1
7.7
12
8
JFA55
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in colon
7.5
7.7
17
23
ZXE20
NOMESCO Finland
More than three and less than five hours
1.6
7.7
209
1408
D11
ICPC
Diarrhoea
1.7
7.7
138
838
WX722
NOMESCO Finland
PEEP
2.0
7.7
79
402
XF404
NOMESCO Finland
Ambulatory ECG
1.7
7.6
143
878
JFG10
NOMESCO Finland
Closure of loop colostomy without resection
4.0
7.6
21
53
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
7.6
120
702
8140/3-C19.9
ICD-O-3
Adenocarcinoma, NOS, of rectosigmoid junction
8.1
7.6
16
20
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.7
7.6
40
152
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
7.6
110
628
J01DA01
ATC
[U] cefalexin
1.4
7.5
858
7441
I50.9
ICD-10 Finland
Heart failure, unspecified
1.5
7.5
238
1656
R03BB04
ATC
tiotropium bromide; inhalant
1.6
7.5
167
1072
J01MA02
ATC
ciprofloxacin; systemic
1.4
7.5
570
4647
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.8
7.5
103
578
M79.6
ICD-10 Finland
Pain in limb
1.4
7.5
572
4669
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.3
7.4
56
252
C187, 8148, 2
ICD-O-3
80.5
7.4
8
*
D50.8
ICD-10 Finland
Other iron deficiency anaemias
3.5
7.4
25
73
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
7.4
296
2162
K80
ICPC
Cardiac arrhythmia NOS
1.7
7.3
124
740
B80
ICPC
Iron deficiency anaemia
2.8
7.3
36
132
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.1
7.3
65
314
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.5
7.2
208
1419
C03DA01
ATC
spironolactone; oral
1.6
7.2
194
1305
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.7
7.2
125
753
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
7.1
253
1802
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
7.1
170
1110
C03CA01
ATC
furosemide; systemic
1.4
7.1
495
3976
C08CA01
ATC
amlodipine; oral
1.3
7.0
613
5089
H01
ICPC
Ear pain/earache
1.7
7.0
131
803
WX320
NOMESCO Finland
Spinalanesthesy
1.4
7.0
358
2728
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
7.0
965
8566
D13.2
ICD-10 Finland
Benign neoplasm: Duodenum
4.4
7.0
17
39
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
6.4
6.9
17
27
M54.5
ICD-10 Finland
Low back pain
1.4
6.9
464
3698
JN4CD
NOMESCO Finland
Very extensive body CT
2.1
6.9
63
307
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
6.7
567
4675
TJX00
NOMESCO Finland
Punkture or biopsy in gastrointestinal endoscopy
16.8
6.7
10
6
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
2.1
6.7
60
290
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
6.7
229
1618
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
3.0
6.7
28
94
PEF23
NOMESCO Finland
Thrombendarterectomy of femoral artery
2.8
6.7
32
116
N06AA09
ATC
amitriptyline; systemic
1.6
6.7
143
910
S17
ICPC
Abrasion/scratch/blister
2.6
6.6
37
145
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
6.6
365
2816
XG466
NOMESCO Finland
Sleep oxymetry
2.3
6.6
48
213
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
6.6
528
4318
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.4
6.6
375
2908
A02BC01
ATC
omeprazole; systemic
1.4
6.6
386
3010
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
6.5
409
3220
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
6.5
133
835
Z25.1
ICD-10 Finland
Need for immunization against influenza
1.9
6.5
75
398
ZXD05
NOMESCO Finland
Urgent procedure
1.4
6.5
404
3180
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.3
6.4
44
191
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.6
6.4
147
952
N05AA02
ATC
levomepromazine; systemic
2.1
6.4
56
269
WX892
NOMESCO Finland
Monitored bed care
1.7
6.4
118
723
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
6.3
707
6053
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
6.3
612
5136
ZXA10
NOMESCO Finland
Bilateral
1.4
6.3
268
1973
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.1
6.3
58
284
C09CA01
ATC
losartan; oral
1.4
6.3
387
3037
J02AC01
ATC
fluconazole; systemic
1.3
6.3
461
3717
K59.0
ICD-10 Finland
Constipation
1.8
6.2
84
469
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
2.6
6.2
34
132
N06AX11
ATC
mirtazapine; oral
1.3
6.2
448
3602
G04CA02
ATC
tamsulosin; oral
1.4
6.2
385
3026
JGB00
NOMESCO Finland
Partial proctectomy and colorectal or coloanal anastomosis
5.8
6.1
16
28
Z71.8
ICD-10 Finland
Other specified counselling
1.4
6.1
371
2901
A02BC03
ATC
lansoprazole; oral
1.4
6.1
415
3303
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
6.1
204
1433
R11
ICD-10 Finland
Nausea and vomiting
1.7
6.1
112
684
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.8
6.1
81
450
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.8
6.1
91
524
G44.2
ICD-10 Finland
Tension-type headache
1.6
6.1
163
1092
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
6.1
176
1200
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.1
6.1
56
274
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
6.1
206
1453
UKC02
NOMESCO Finland
Cystoscopy
1.4
6.1
249
1822
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
6.0
580
4856
SPAT1097
SPAT
Recording of ECG
1.5
6.0
222
1592

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
583
1421
6.04
240.43
1.5
1.3
—
—
—
0
0
375
1524
2.94
64.96
4.7
4.1
10.18
21.19
ug/l
0.99
297
1262
855
5903
2.03
38.92
6.1
6.0
2.78
2.88
%
0.61
798
5505
766
5087
2.02
38.90
2.6
2.2
—
—
—
0
0
855
5926
2.02
38.22
6.4
6.3
8.96
8.84
%
0.45
807
5527
196
739
2.90
37.56
2.8
2.4
—
—
—
0
0
831
5730
2.00
37.38
6.1
6.0
0.67
0.68
%
0.22
777
5333
850
5921
1.99
36.97
6.1
6.0
58.21
57.88
%
0.34
795
5535
857
6028
1.97
35.76
6.3
6.2
26.58
26.77
%
0.19
804
5639
564
3450
2.01
35.20
2.7
2.2
3.28
3.09
mg/l
0.79
493
2913
626
3991
1.97
34.52
3.5
3.3
29.75
34.78
u/l
2.77
593
3781
355
1855
2.19
33.52
1.4
1.2
—
—
—
0
0
950
7020
1.95
33.14
7.1
6.4
10.98
11.81
umol/l
2.11
904
6652
1239
10079
2.25
32.92
9.4
7.8
79.18
79.34
u/l
0.04
1195
9467
362
1993
2.07
29.39
2.6
2.5
2.37
2.29
g/l
1.52
342
1849
733
5117
1.84
29.02
3.4
2.8
124.39
150.94
ug/l
2.12
691
4644
859
6299
1.84
28.92
6.1
5.8
0.04
0.04
e9/l
0.41
742
5405
819
5921
1.83
28.86
6.1
6.4
—
—
—
0
0
879
6502
1.84
28.65
6.3
5.9
0.20
0.20
e9/l
0.08
765
5663
911
6819
1.84
28.50
7.2
7.0
1.22
1.21
mmol/l
0.70
798
5778
856
6287
1.83
28.49
6.1
5.8
0.64
0.61
e9/l
3.24
743
5391
865
6414
1.81
27.48
6.2
5.8
1.89
1.93
e9/l
0.20
753
5629
1160
9442
1.97
27.19
4.9
4.2
14.22
13.53
mm/h
0.70
1094
8673
341
1886
2.04
27.09
2.7
2.6
20.29
22.42
%
1.76
297
1606
787
5717
1.78
26.38
2.3
2.1
95.27
94.30
pmol/l
0.21
417
2979
373
2152
1.97
26.19
2.6
2.5
11.88
12.63
umol/l
0.98
356
2000
810
5957
1.77
25.80
5.7
4.8
35.04
35.01
g/l
0.04
758
5542
953
7356
1.80
25.62
9.5
9.2
4.24
4.19
e9/l
0.21
820
6417
279
1461
2.11
25.53
2.7
2.7
6.96
8.82
umol/l
1.47
237
1292
880
6674
1.76
24.75
18.1
17.3
1.32
1.32
inr
0.01
241
1911
613
4211
1.77
24.31
2.6
2.6
—
—
—
0
0
247
1269
2.13
23.63
2.0
2.2
132.26
145.33
ug/g
0.16
204
1013
605
4194
1.74
22.86
2.9
2.5
60.93
78.96
u/l
0.45
572
3862
975
7722
1.74
22.44
3.9
3.2
54.07
54.81
u/l
0.09
922
7094
1080
8820
1.78
22.14
5.0
4.5
—
—
—
0
0
825
6265
1.70
21.97
6.6
6.2
1.21
1.21
mmol/l
0.94
761
5688
984
7845
1.72
21.78
5.8
4.9
6.87
6.85
mmol/l
0.07
943
7418
1387
12363
2.43
21.38
22.3
16.1
25.34
25.73
mg/l
0.15
1204
9978
500
3346
1.74
21.03
5.1
4.0
87.10
87.13
%
0.01
489
3270
788
6096
1.61
18.04
2.7
2.7
—
—
—
0
0
1026
8542
1.62
16.65
5.3
4.7
164.15
2142.36
e6/l
1.97
13
137
413
2777
1.67
16.31
3.2
3.0
520.15
541.05
mosm/kgh2o
1.17
345
2373
465
3239
1.63
15.91
2.5
2.5
—
—
—
0
0
480
3382
1.61
15.62
1.6
1.6
19.92
20.56
nmol/l
0.43
409
2838
625
4686
1.57
15.59
4.4
3.8
55.63
109.39
e6/l
1.55
454
3439
337
2181
1.70
15.24
3.4
3.0
2.04
2.12
e6/l
0.07
202
1226
558
4110
1.57
14.86
3.9
3.3
37.36
81.05
e6/l
1.68
440
3218
1273
11357
1.75
14.25
5.4
4.7
1.93
2.10
mu/l
0.84
1186
10240
394
2698
1.62
14.18
4.7
4.0
479.74
356.28
ng/l
0.24
322
2241
271
1691
1.73
13.88
2.9
2.5
1.83
1.80
%
0.17
239
1500
586
4425
1.53
13.65
3.4
3.1
2116.42
1482.32
ng/l
1.26
513
3819
451
3217
1.57
13.57
7.4
6.9
—
—
—
0
0
1083
9329
1.56
13.40
4.2
3.9
14.96
14.98
pmol/l
0.13
997
8364
346
2325
1.63
13.33
3.3
2.8
1.03
1.13
e6/l
0.24
210
1366
116
554
2.18
13.16
3.4
3.4
5874.53
7287.62
u/ml
0.07
95
476
136
693
2.06
13.04
1.5
1.8
1.69
1.57
g/l
0.76
116
598
1410
13074
2.12
12.85
25.9
19.1
139.66
139.64
mmol/l
0.10
1387
12744
509
3770
1.53
12.77
3.8
3.2
0.40
0.49
e6/l
0.55
401
2925
206
1216
1.80
12.71
2.7
2.3
32.70
37.19
u/l
0.85
178
1036
207
1227
1.80
12.59
2.6
3.0
66.53
66.32
g/l
0.16
184
1114
1411
13106
2.11
12.49
26.1
19.2
3.98
3.99
mmol/l
1.14
1389
12764
385
2704
1.57
12.19
1.8
1.7
1.34
1.33
mg/l
0.01
308
2121
540
4094
1.50
11.93
5.0
4.2
7.40
7.40
ph
0.03
86
792
394
2801
1.55
11.76
1.9
1.8
1011.16
1185.31
nmol/l
3.48
305
2086
1413
13172
2.07
11.73
14.1
11.2
25.23
25.65
u/l
0.46
1379
12661
1341
12300
1.78
11.62
5.7
5.0
6.16
6.06
mmol/l
1.90
1250
11068
178
1032
1.82
11.62
2.1
2.7
—
—
—
0
0
115
575
2.08
11.60
2.0
2.7
3.78
3.62
g/l
0.56
106
519
487
3634
1.50
11.55
3.7
3.2
—
—
—
0
0
115
576
2.08
11.55
2.0
2.7
7.36
7.40
g/l
0.09
106
519
594
4618
1.47
11.45
4.2
3.5
2.36
2.35
mmol/l
0.92
524
4027
658
5221
1.46
11.40
2.4
2.2
77.05
78.73
nmol/l
0.81
594
4591
329
2261
1.58
11.34
3.9
3.3
0.80
0.81
mmol/l
1.31
309
2114
318
2170
1.59
11.30
1.5
1.5
2.67
2.59
g/l
0.27
177
1293
242
1543
1.68
11.29
1.4
1.3
724.26
529.66
titre
0.52
47
348
108
538
2.08
11.01
1.8
2.8
10.66
10.49
g/l
0.14
98
480
157
899
1.83
10.66
3.6
3.9
7.39
7.40
ph
0.13
14
118
124
660
1.96
10.52
3.7
3.9
—
—
—
0
0
398
2905
1.50
10.30
2.7
2.6
4.47
5.44
e6/l
0.93
348
2617
514
3947
1.46
10.30
4.8
4.4
—
—
—
0
0
663
5345
1.43
10.17
4.5
4.0
53.40
49.32
ng/l
0.12
504
4023
157
912
1.80
10.16
3.7
3.8
5.12
5.18
kpa
0.41
145
878
211
1337
1.67
10.03
2.6
2.1
0.22
0.21
g/l
0.99
198
1248
107
554
2.00
9.83
3.5
4.2
24.45
25.06
mmol/l
1.26
94
515
184
1131
1.71
9.79
1.6
1.5
—
—
—
0
0
250
1663
1.60
9.78
1.2
1.3
—
—
—
0
0
679
5535
1.41
9.61
11.6
10.2
0.00
0.00
e9/l
0.19
555
4520
568
4491
1.42
9.54
4.1
3.8
10.72
8.89
mg/mmol
0.39
377
2834
86
416
2.13
9.48
3.8
3.3
—
—
—
0
0
1169
10510
1.49
9.47
27.5
19.1
16.09
15.36
%
2.84
1159
10312
335
2397
1.51
9.44
1.3
1.2
3.01
1.56
u/ml
0.47
69
627
540
4253
1.42
9.18
3.4
3.3
642.40
268.07
mg/l
0.78
354
2730
1363
12722
1.71
8.98
20.0
15.5
—
—
—
0
0
528
4161
1.41
8.88
4.9
4.1
—
—
—
0
0
90
457
2.03
8.74
2.0
2.6
38.23
37.36
g/l
0.74
81
401
142
838
1.77
8.71
1.2
1.2
—
—
—
0
0
270
1878
1.53
8.62
6.7
5.6
1.04
1.03
mmol/l
0.16
257
1731
534
4237
1.40
8.56
3.4
3.3
—
—
—
0
0
530
4202
1.40
8.53
2.2
2.2
197.66
223.79
u/l
0.32
495
3940
136
799
1.77
8.47
1.2
1.3
—
—
—
0
0
1281
11821
1.54
8.36
7.6
6.3
40.79
40.65
mmol/mol
0.20
1196
10838
245
1679
1.55
8.35
6.4
7.5
0.92
1.20
mmol/l
0.53
202
1339
1428
13550
1.93
8.35
33.0
23.8
6.96
6.78
e9/l
2.14
1395
13124
544
4346
1.39
8.32
3.4
3.2
7.52
7.37
mmol/l
0.36
454
3624
189
1221
1.63
8.28
1.4
1.4
—
—
—
0
0
1427
13548
1.91
8.17
33.1
23.8
246.47
244.26
e9/l
0.60
1398
13168
1427
13549
1.91
8.15
33.0
23.7
91.41
91.57
fl
0.64
1406
13318
1427
13551
1.90
8.12
33.0
23.8
4.40
4.44
e12/l
2.21
1396
13128
1426
13540
1.90
8.09
33.1
24.0
39.51
39.80
%
1.01
1337
12562
1427
13553
1.90
8.09
33.3
24.0
132.27
134.30
g/l
5.23
1406
13318
224
1519
1.56
7.99
6.3
7.8
95.43
95.36
%
0.06
219
1466
243
1678
1.53
7.99
6.4
7.5
5.01
5.10
kpa
0.77
236
1606
1426
13549
1.88
7.94
32.9
23.7
30.30
30.43
pg
1.86
1407
13317
195
1287
1.59
7.82
8.1
7.3
10.58
10.51
mmol/l
0.04
184
1225
242
1679
1.53
7.77
6.5
7.4
12.08
11.83
kpa
0.34
233
1610
79
401
2.02
7.71
1.5
1.6
—
—
—
0
0
453
3549
1.39
7.65
2.9
2.8
4763.77
6436.88
umol/l
0.36
392
3053
280
2019
1.47
7.44
1.3
1.3
32.92
35.37
iu/ml
0.11
80
660
208
1412
1.55
7.37
3.7
4.5
—
—
—
0
0
90
489
1.89
7.23
3.4
3.1
0.24
0.27
g/l
0.19
41
189
190
1269
1.57
7.23
2.6
2.7
71.67
69.29
e9/l
0.43
140
988
128
778
1.70
7.09
7.2
10.2
—
—
—
0
0
74
383
1.98
6.87
1.3
1.5
316.93
271.03
ug/g
1.06
43
236
185
1246
1.55
6.78
6.3
7.1
1.30
1.39
mmol/l
0.70
176
1220
177
1187
1.56
6.61
7.9
8.4
—
—
—
0
0
271
1988
1.44
6.53
2.0
2.1
—
—
—
0
0
1303
12207
1.48
6.48
5.2
4.7
1.42
1.45
mmol/l
1.79
1212
11060
1337
12596
1.52
6.41
5.9
5.3
2.61
2.66
mmol/l
0.96
1255
11444
163
1084
1.56
6.31
4.1
3.7
91.84
94.02
ng/l
0.12
140
937
115
703
1.69
6.25
4.0
3.8
—
—
—
0
0
186
1282
1.51
6.12
2.9
3.0
232.24
221.21
ng/l
0.12
172
1177
1309
12304
1.47
6.10
5.2
4.7
4.51
4.56
mmol/l
0.91
1213
11242
14
24
5.88
5.53
1.0
1.1
—
—
—
0
0
29
112
2.62
5.40
1.2
1.3
—
34.71
—
0
7
144
969
1.54
5.31
1.6
1.4
—
—
—
0
0
43
202
2.16
5.23
1.7
1.6
218.13
274.21
mu/l
1.67
38
185
429
3503
1.31
5.18
1.7
1.7
1.39
1.36
mmol/l
0.33
367
2890
578
4916
1.28
5.11
3.6
3.6
5.55
5.82
ph
1.14
22
279
1010
9216
1.29
5.00
4.6
4.2
—
—
—
0
0
122
807
1.56
4.87
2.6
2.5
22.78
21.97
au/ml
—
10
45
1255
11817
1.36
4.82
4.6
4.2
1.34
1.30
mmol/l
1.11
1152
10616
335
2667
1.33
4.80
4.1
3.1
2.47
2.46
mmol/l
0.80
292
2359
65
371
1.79
4.57
4.4
5.0
—
—
—
0
0
229
1733
1.38
4.56
5.2
4.7
32.38
32.78
%
0.25
177
1147
110
722
1.56
4.55
1.5
1.3
43.83
57.72
au/ml
—
6
44
206
1538
1.39
4.45
1.9
1.7
—
—
—
0
0
56
308
1.85
4.44
4.1
3.3
145.41
1246.00
u/ml
0.74
49
290
114
768
1.52
4.22
1.9
1.8
1.52
1.50
g/l
0.03
107
704
36
175
2.08
4.08
1.2
1.1
—
—
—
0
0
135
959
1.45
3.86
2.8
2.9
10.97
10.77
g/l
0.17
129
881
16
54
2.98
3.85
4.1
2.4
—
—
—
0
0
35
173
2.05
3.81
1.3
1.7
0.80
0.88
g/l
0.18
25
135
381
3172
1.27
3.81
1.3
1.3
—
—
—
0
0
176
1316
1.38
3.77
5.0
3.6
1.75
2.08
mmol/l
0.60
159
1080
40
209
1.94
3.74
1.4
1.3
11.06
9.99
u/l
0.14
28
166
115
804
1.47
3.59
7.1
7.9
25.31
24.89
mmol/l
0.57
115
799
202
1561
1.34
3.52
1.4
1.4
—
—
—
0
0
23
99
2.34
3.51
1.2
1.3
0.42
0.41
g/l
0.05
18
70
23
99
2.34
3.51
1.2
1.3
8.26
7.47
g/l
0.21
18
70
242
1920
1.31
3.51
1.3
1.2
27.78
13.12
u/ml
1.25
73
701
582
5117
1.22
3.50
5.8
5.2
2.06
2.96
ug/l
2.99
519
4558
58
348
1.69
3.50
1.3
1.7
—
—
—
0
0
94
635
1.51
3.48
1.3
1.2
—
—
—
0
0
175
1328
1.36
3.43
4.9
3.5
5.76
5.84
kpa
0.60
170
1286
146
1078
1.39
3.39
1.7
1.5
—
—
—
0
0
29
140
2.09
3.39
1.2
1.2
—
—
—
0
0
46
263
1.77
3.30
1.6
1.3
55.88
59.24
mmol/l
0.27
34
214
95
651
1.49
3.29
1.1
1.2
98.71
144.54
iu/ml
0.58
35
250
152
1138
1.37
3.25
2.1
2.2
390.63
370.78
nmol/l
0.63
138
1038
23
103
2.25
3.23
1.2
1.3
—
—
—
0
0
84
564
1.52
3.22
2.1
1.9
—
—
—
0
0
688
6192
1.20
3.16
4.0
3.9
0.01
0.00
estimate
0.32
115
1248
56
344
1.65
3.12
2.9
2.4
—
—
—
0
0
33
173
1.93
3.11
1.2
1.1
—
—
—
0
0
52
314
1.68
3.09
3.1
2.6
—
—
—
0
0
30
153
1.98
3.06
2.9
3.2
—
—
—
0
0
1060
9956
1.22
3.02
30.1
21.3
330.89
331.85
g/l
2.78
1052
9887
125
918
1.39
3.02
2.8
2.2
12.95
12.63
nmol/l
0.17
106
811
150
1135
1.36
3.02
1.7
1.5
—
—
—
0
0
117
851
1.41
2.99
3.5
3.0
—
—
—
0
0
23
108
2.15
2.91
1.2
1.2
382.60
370.08
nmol/l
0.08
15
90
133
995
1.37
2.88
4.2
4.8
—
—
—
0
0
75
506
1.51
2.84
2.9
3.9
61.90
64.86
mg/l
0.07
63
411
75
506
1.51
2.84
2.9
3.9
45.86
80.17
mg/l
0.67
63
413
49
299
1.66
2.83
2.1
2.3
123.73
128.62
g/l
0.62
30
227
19
86
2.22
2.64
1.1
1.1
—
—
—
0
0
31
169
1.85
2.64
2.5
2.6
—
—
—
0
0
29
155
1.89
2.62
2.1
2.4
1.57
1.22
g/24h
0.38
14
77
66
442
1.52
2.61
2.1
2.0
21.15
21.60
s
0.44
60
396
166
1305
1.31
2.59
1.7
1.5
—
—
—
0
0
115
856
1.37
2.59
3.7
3.0
5.73
5.96
e9/l
0.05
91
660
30
163
1.86
2.58
1.5
1.5
—
—
—
0
0
347
2975
1.22
2.57
3.7
3.8
—
—
—
0
0
16
68
2.37
2.56
2.9
2.1
15.55
17.23
nmol/l
0.43
16
62
18
81
2.24
2.54
2.9
1.6
17.12
3776.38
u/l
—
5
24
51
326
1.58
2.48
1.2
1.2
101.67
97.31
titre
—
6
26
678
6188
1.17
2.45
5.7
5.2
0.00
0.00
estimate
-0.00
110
1168
684
6253
1.17
2.41
4.1
3.9
0.00
0.01
estimate
0.80
107
1127
7
17
4.13
2.36
1.7
1.5
—
—
—
0
0
32
184
1.76
2.33
2.8
2.6
—
—
—
0
0
27
149
1.83
2.25
1.1
1.2
—
—
—
0
0
84
610
1.40
2.23
2.3
2.8
—
—
—
0
0
19
93
2.06
2.22
3.5
3.4
—
—
—
0
0
36
219
1.66
2.16
1.9
2.7
—
—
—
0
0
47
306
1.55
2.15
4.4
3.3
7.14
7.67
mmol/l
1.10
47
298
26
144
1.82
2.15
1.9
2.3
—
—
—
0
0
35
215
1.64
2.04
1.3
1.5
33.57
31.93
g/l
0.24
27
195
6
15
4.01
2.04
1.7
1.3
79.50
36.93
umol/l
—
6
15
84
622
1.37
2.01
2.0
1.9
1.55
2.54
ug/l
0.48
75
551
139
1111
1.28
1.96
4.1
2.8
4.70
4.54
kpa
0.39
133
1073
53
364
1.47
1.93
1.2
1.1
—
—
—
0
0
77
567
1.38
1.92
1.2
1.2
—
—
—
0
0
28
165
1.71
1.91
1.1
1.2
—
0.46
—
0
13
48
326
1.49
1.85
4.3
3.2
1.52
1.59
mmol/l
0.32
48
317
85
640
1.35
1.85
3.0
3.2
4.43
4.43
pmol/l
0.00
74
555
33
207
1.61
1.80
1.2
1.3
—
—
—
0
0
18
94
1.93
1.80
1.1
1.4
—
—
—
0
0
25
146
1.72
1.78
1.1
1.3
—
—
—
0
0
55
389
1.43
1.74
1.1
1.1
—
—
—
0
0
39
259
1.52
1.69
1.3
1.6
—
—
—
0
0
91
703
1.31
1.69
1.4
1.4
—
—
—
0
0
24
141
1.71
1.68
1.2
1.2
—
—
nmol/l
—
0
0
90
695
1.31
1.68
3.4
2.5
1.23
1.17
%
0.20
90
690
126
1018
1.26
1.66
3.6
4.2
0.00
0.38
%
0.71
27
300
25
150
1.68
1.64
4.1
1.4
—
—
—
0
0
25
150
1.68
1.64
4.1
1.4
—
—
—
0
0
25
152
1.66
1.57
4.1
1.4
—
—
—
0
0
25
152
1.66
1.57
4.1
1.4
—
—
—
0
0
22
129
1.72
1.57
1.0
1.2
—
—
—
0
0
333
2966
1.16
1.56
3.6
3.2
0.93
0.76
ug/l
0.63
255
2064
26
161
1.63
1.53
1.3
1.4
—
—
—
0
0
23
138
1.68
1.52
1.2
1.2
—
—
—
0
0
27
416
0.64
1.49
14.2
11.2
—
—
—
0
0
14
72
1.95
1.49
1.3
1.5
—
—
—
0
0
339
3035
1.15
1.48
1.8
1.7
31295401.08
25591302.70
pmol/l
0.07
278
2454
307
3436
0.87
1.46
4.7
4.2
0.02
0.00
estimate
0.37
107
1115
11
52
2.12
1.44
39.5
26.3
100.73
127.61
ug/l
1.01
11
41
6
22
2.73
1.43
2.0
1.0
—
—
—
0
0
28
180
1.57
1.43
1.1
1.1
—
—
—
0
0
23
141
1.64
1.42
4.3
1.4
—
—
—
0
0
44
313
1.42
1.40
1.5
1.2
31.71
7.07
u/ml
—
7
47
29
190
1.54
1.38
1.1
1.1
—
—
—
0
0
51
374
1.38
1.37
2.5
4.1
—
—
—
0
0
24
151
1.60
1.35
1.2
1.5
6.89
6.59
mmol/l
0.19
18
143
47
341
1.39
1.35
1.6
1.5
0.22
0.23
g/l
0.83
42
321
14
75
1.87
1.34
6.2
1.5
—
—
—
0
0
129
1074
1.22
1.33
3.8
4.2
0.18
0.11
%
0.46
28
354
136
1141
1.21
1.31
3.6
4.1
1.13
0.92
%
0.23
34
418
124
1031
1.22
1.30
3.6
3.9
0.53
0.69
%
0.34
30
355
10
48
2.09
1.27
1.3
1.9
—
—
—
0
0
9
44
2.05
1.27
26.6
16.2
1165.56
1640.55
nmol/l
—
9
44
22
138
1.60
1.26
1.2
1.4
211.21
332.09
pmol/l
1.66
22
124
19
115
1.66
1.25
4.6
1.4
—
—
—
0
0
44
321
1.38
1.24
4.0
3.2
7.40
7.91
kpa
1.46
44
315
26
171
1.53
1.23
1.3
1.3
84594.55
103024.20
e6/l
0.11
11
105
26
171
1.53
1.23
1.3
1.6
63.79
64.20
%
0.02
14
112
15
85
1.77
1.23
1.1
1.2
—
—
—
0
0
35
246
1.43
1.22
3.6
3.2
59.83
59.05
%
0.10
35
246
14
78
1.80
1.21
1.3
1.8
—
—
—
0
0
25
164
1.53
1.20
1.5
2.4
—
—
—
0
0
38
273
1.40
1.18
1.3
1.5
0.92
0.86
nmol/l
0.20
32
222
153
1313
1.18
1.17
2.4
2.5
5.99
7.16
ug/l
0.71
127
1161
10
50
2.01
1.16
1.8
2.2
—
—
—
0
0
8
39
2.06
1.15
1.3
1.5
—
—
—
0
0
50
378
1.33
1.15
1.1
1.1
—
—
—
0
0
7
30
2.34
1.12
1.9
1.4
—
—
—
0
0
33
234
1.42
1.11
1.3
1.3
32.40
32.16
iu/l
0.01
20
197
136
1163
1.19
1.10
5.2
3.9
1.23
1.22
mmol/l
0.27
119
1006
31
218
1.43
1.09
1.6
1.4
—
—
—
0
0
47
356
1.33
1.08
1.7
1.5
1.13
1.17
g/l
0.29
41
338
9
46
1.96
1.03
3.0
2.5
—
—
—
0
0
30
416
0.72
1.03
1.5
1.4
—
—
—
0
0
19
122
1.56
1.02
3.5
3.3
22.93
31.51
mg/l
0.19
12
96
40
299
1.35
1.01
1.5
1.2
—
—
—
0
0
9
48
1.88
1.00
1.9
2.4
—
—
—
0
0
14
84
1.67
0.98
1.8
3.3
7.45
7.42
ph
—
6
28
16
100
1.61
0.97
1.4
1.2
—
—
—
0
0
46
355
1.31
0.95
1.2
1.2
—
—
—
0
0
46
356
1.30
0.94
2.0
2.1
11.17
11.91
mg/l
0.30
40
326
23
159
1.45
0.91
1.4
1.2
2.31
5.16
u/ml
1.22
13
76
18
118
1.53
0.91
1.3
1.4
17.79
28.83
%
—
10
74
14
86
1.63
0.91
1.3
1.2
—
—
—
0
0
46
584
0.78
0.89
7.2
4.6
—
—
—
0
0
368
3956
0.91
0.88
3.8
3.1
—
—
—
0
0
6
30
2.00
0.87
1.0
1.4
—
159.14
—
0
7
6
30
2.00
0.87
5.0
4.2
—
—
—
0
0
23
161
1.44
0.86
1.5
1.2
—
—
—
0
0
11
64
1.72
0.86
1.0
1.0
—
—
—
0
0
19
128
1.49
0.86
1.5
1.4
—
—
—
0
0
16
104
1.54
0.84
1.1
1.0
—
—
—
0
0
8
45
1.78
0.84
1.4
1.2
204.75
248.91
iu/ml
—
8
45
6
32
1.88
0.82
1.7
2.1
—
—
—
0
0
30
224
1.35
0.80
1.9
2.2
—
—
—
0
0
0
24
0.00
0.79
0.0
1.5
—
—
—
0
0
6
33
1.82
0.79
1.2
1.1
—
—
—
0
0
15
98
1.54
0.78
6.4
1.8
—
—
—
0
0
252
2742
0.90
0.78
4.7
4.3
1.02
1.02
kg/l
0.58
46
411
30
226
1.33
0.76
5.7
3.1
—
—
—
0
0
347
3238
1.09
0.75
3.9
3.6
—
—
—
0
0
11
67
1.65
0.75
1.9
2.8
1897.27
1900.17
ml
0.00
11
58
11
67
1.65
0.75
1.0
1.2
151.36
140.14
nmol/l
0.27
11
67
104
1191
0.86
0.74
3.6
3.4
—
—
—
0
0
7
38
1.85
0.73
2.1
1.5
—
—
—
0
0
7
39
1.80
0.72
1.0
1.1
209.14
247.32
pmol/l
—
7
25
33
255
1.30
0.72
1.8
1.8
3.76
5.07
iu/l
—
9
77
37
465
0.79
0.70
1.8
1.5
—
—
—
0
0
20
143
1.40
0.70
1.5
1.6
—
—
—
0
0
26
195
1.34
0.69
1.4
1.4
867.67
1705.71
e6/l
2.51
15
144
27
204
1.33
0.69
1.4
1.4
—
—
—
0
0
35
275
1.28
0.68
3.8
3.1
—
—
—
0
0
7
42
1.67
0.68
2.0
1.8
—
—
—
0
0
39
311
1.26
0.68
4.2
4.2
—
—
—
0
0
26
196
1.33
0.68
1.2
1.3
294.78
179.11
miu/ml
—
9
81
28
214
1.31
0.67
3.0
2.6
—
—
—
0
0
21
154
1.37
0.65
1.4
1.4
—
—
—
0
0
5
29
1.73
0.64
10.8
5.8
—
—
—
0
0
43
351
1.23
0.63
3.1
3.1
0.82
0.84
nmol/l
0.10
32
273
34
270
1.27
0.62
1.4
1.2
—
—
—
0
0
28
217
1.30
0.62
1.1
1.4
—
—
—
0
0
134
1205
1.12
0.61
1.5
1.5
—
—
—
0
0
30
235
1.28
0.61
3.9
2.9
4.90
4.47
e9/l
0.33
30
235
8
51
1.57
0.60
2.1
2.2
—
—
—
0
0
31
245
1.27
0.60
1.3
1.3
—
—
—
0
0
30
377
0.79
0.59
2.0
1.7
—
—
—
0
0
60
511
1.18
0.58
2.8
2.2
219.18
464.65
ug/l
1.42
60
484
6
35
1.72
0.57
1.0
1.0
—
—
—
0
0
8
54
1.48
0.57
1.0
1.3
—
—
—
0
0
6
36
1.67
0.56
1.0
1.4
89.43
66.96
mu/l
—
6
26
20
151
1.33
0.54
1.3
1.2
—
—
—
0
0
74
652
1.14
0.49
1.3
1.2
137.97
191.94
u/ml
0.84
69
595
12
85
1.42
0.47
1.1
1.5
85.42
85.05
umol/l
0.04
12
85
7
49
1.43
0.46
1.0
1.2
—
—
—
0
0
42
357
1.18
0.45
1.4
1.7
8025.45
16713.66
e6/l
1.60
31
264
5
32
1.56
0.42
1.4
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
11
79
1.40
0.40
2.3
1.5
1.14
0.98
g/l
0.64
11
79
0
18
0.00
0.40
0.0
2.5
—
104.00
—
0
5
5
35
1.43
0.39
2.2
1.7
—
—
—
0
0
5
35
1.43
0.39
1.4
1.4
—
—
—
0
0
9
66
1.37
0.38
1.0
1.1
—
—
—
0
0
9
69
1.31
0.37
1.0
1.0
—
—
—
0
0
6
47
1.28
0.32
1.2
1.4
13.17
14.91
g/l
—
6
35
65
589
1.11
0.32
1.3
1.3
—
—
—
0
0
13
101
1.29
0.31
2.0
1.2
—
—
—
0
0
30
258
1.17
0.31
1.4
1.6
—
—
—
0
0
16
129
1.24
0.30
1.2
1.0
5.19
2.36
u/ml
—
7
46
11
84
1.31
0.30
1.5
1.2
—
—
—
0
0
11
86
1.28
0.26
2.4
2.2
—
—
—
0
0
9
73
1.23
0.25
1.0
1.1
—
—
—
0
0
13
105
1.24
0.24
2.2
1.8
2.00
2.40
u/field
—
6
42
17
142
1.20
0.24
1.2
1.3
26314.64
87386.09
e6/l
0.62
11
97
9
76
1.19
0.24
1.2
2.9
—
—
—
0
0
12
96
1.25
0.24
1.8
1.2
—
—
—
0
0
6
85
0.70
0.24
2.2
2.3
13.08
13.31
%
—
6
85
35
314
1.12
0.22
1.1
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
44.60
—
0
5
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
5
43
1.16
0.21
1.0
1.1
1197.80
1649.51
miu/ml
—
5
43
31
279
1.11
0.19
1.3
1.3
3.73
40.28
e6/l
1.02
22
218
31
279
1.11
0.19
1.4
1.4
194.84
646.89
e6/l
0.57
25
226
6
52
1.15
0.19
6.2
3.0
—
—
—
0
0
10
81
1.24
0.18
1.4
1.4
2.17
0.96
promille
—
10
63
11
132
0.83
0.18
1.0
1.1
—
—
—
0
0
15
129
1.16
0.17
1.0
1.1
—
—
—
0
0
5
69
0.72
0.17
1.2
1.4
4.40
8.66
ug/l
—
5
59
8
73
1.10
0.15
1.0
1.3
181.64
148.54
pmol/l
—
8
73
63
667
0.94
0.15
1.2
1.4
—
—
—
0
0
27
245
1.10
0.15
1.7
1.9
2.08
1.67
mmol/l
0.55
27
240
14
121
1.16
0.15
1.1
1.1
0.07
1.95
u/ml
—
6
57
31
284
1.09
0.15
1.3
1.3
—
—
—
0
0
114
1096
1.04
0.14
4.1
4.0
—
—
—
0
0
7
88
0.79
0.14
2.4
2.6
—
—
—
0
0
15
168
0.89
0.11
6.7
4.5
—
—
—
0
0
11
126
0.87
0.11
1.2
1.1
—
—
—
0
0
14
124
1.13
0.11
1.4
1.2
—
—
—
0
0
26
241
1.08
0.10
1.2
1.5
—
—
—
0
0
11
125
0.88
0.10
1.2
1.1
—
—
—
0
0
33
310
1.07
0.10
2.9
2.6
15.64
16.03
%
0.24
20
158
38
362
1.05
0.07
2.2
2.2
296.09
108.70
ug/min
0.66
25
220
11
98
1.12
0.07
2.7
2.1
1.06
1.10
e9/l
0.06
11
92
8
74
1.08
0.07
5.4
15.6
—
—
—
0
0
8
77
1.04
0.07
1.8
1.7
—
—
—
0
0
12
108
1.11
0.07
1.0
1.0
0.81
4.88
u/ml
—
7
43
7
81
0.86
0.07
1.1
1.1
241.43
258.86
mg/l
—
7
72
7
80
0.87
0.07
1.0
1.3
—
—
—
0
0
13
118
1.10
0.07
1.2
1.2
1.32
1.38
nmol/l
0.07
13
101
9
87
1.03
0.07
1.1
1.1
1.71
2.01
mmol/l
—
9
81
9
88
1.02
0.07
1.4
2.7
—
—
—
0
0
21
200
1.05
0.03
1.5
1.2
328.67
300.63
u/ml
0.15
15
108
33
319
1.04
0.03
5.3
5.2
3.18
2.73
mmol/l
0.39
26
224
12
114
1.05
0.00
1.8
1.8
11.97
10.99
%
0.36
12
114
25
246
1.02
0.00
1.7
1.8
—
—
—
0
0
10
99
1.01
0.00
1.2
1.2
—
—
—
0
0
10
101
0.99
0.00
2.4
2.3
—
—
—
0
0
29
291
1.00
0.00
4.6
3.8
32.65
26.93
mg/l
0.23
19
186
11
105
1.05
0.00
1.0
1.0
0.55
2.36
u/ml
—
5
36
6
61
0.98
-0.00
5.3
6.3
—
—
—
0
0
9
92
0.98
-0.00
1.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
5
59
0.85
-0.00
1.4
1.3
1.36
1.57
g/l
—
5
59
8
85
0.94
-0.00
1.1
1.2
47.58
39.15
mg/l
—
8
75
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
17
170
1.00
-0.00
1.4
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.4
183.80
176.27
mmol/24h
—
5
50
7
72
0.97
-0.00
1.0
1.3
0.61
1.20
nmol/l
—
7
55
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
2.43
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
380.33
—
0
9

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_RECTOSIGMOID_JUNC and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_RECTOSIGMOID_JUNC 1.169 [1.03, 1.32] 0.013
Birth year 0.997 [0.99, 1.01] 0.425

During the follow-up period (1.1.1998 — 31.12.2019), 680 out of 3167 females with CD2_BENIGN_RECTOSIGMOID_JUNC died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_RECTOSIGMOID_JUNC 1.224 [1.08, 1.39] 0.001
Birth year 0.986 [0.97, 1.0] 0.02

During the follow-up period (1.1.1998 — 31.12.2019), 919 out of 3357 males with CD2_BENIGN_RECTOSIGMOID_JUNC died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_RECTOSIGMOID_JUNC.

N-year risk Females Males
1 0.101% 0.256%
5 0.705% 1.504%
10 1.808% 3.471%
15 3.541% 6.366%
20 6.085% 10.725%

Relationships between endpoints

Index endpoint: CD2_BENIGN_RECTOSIGMOID_JUNC – Benign neoplasm: Rectosigmoid junction

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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