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Autoimmune hepatitis

EFO Endpoint Browser PheWeb

AUTOHEP

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K75.4
  • Cause of death: ICD-10 — K75.4

2 out of 7 registries used, show all original rules.

324

4. Check minimum number of events

None

324

5. Include endpoints

None

324

6. Filter based on genotype QC (FinnGen only)

311

Control definitions (FinnGen only)

Control exclude
AUTOIMMUNE

Extra metadata

First used in FinnGen datafreeze
DF11

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 311 231 80
Unadjusted period prevalence (%) 0.07 0.08 0.04
Median age at first event (years) 63.39 63.66 62.59

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
324
Matched controls
3240
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K75.4
ICD-10 Finland
Autoimmune hepatitis
+∞
307.7
324
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
104.0
307.7
196
47
A07EA06
ATC
budesonide; oral, local oral
191.8
307.7
172
19
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
191.6
307.7
180
21
L04AX01
ATC
azathioprine; systemic
1371.2
280.2
234
6
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
4058.3
211.9
181
*
A05AA02
ATC
ursodeoxycholic acid; oral
80.0
145.7
79
13
K76.9
ICD-10 Finland
Liver disease, unspecified
85.4
136.3
73
11
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
80.9
129.6
70
11
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
15.2
120.7
132
140
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
31.0
95.1
65
26
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
185.4
92.7
93
7
H02AB06
ATC
prednisolone; systemic
13.8
87.9
277
968
H03AA01
ATC
levothyroxine sodium; systemic
11.8
78.2
93
107
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
8.1
76.8
222
683
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
918.3
76.5
72
*
L01BB02
ATC
mercaptopurine; oral
230.3
72.4
72
*
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
23.3
70.1
53
27
L04AA06
ATC
mycophenolic acid; systemic
140.7
55.9
58
5
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.3
49.0
163
522
P01BA02
ATC
hydroxychloroquine; oral
11.8
43.2
47
46
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.0
43.2
94
206
K74.3
ICD-10 Finland
Primary biliary cirrhosis
+∞
41.6
39
*
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
73.5
34.9
39
6
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
34.0
32
*
K51.5
ICD-10 Finland
Left sided colitis
370.2
33.5
33
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
12.1
31.6
33
30
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
34.9
31.2
40
13
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
+∞
30.7
29
*
K83.0
ICD-10 Finland
Cholangitis
55.8
30.0
35
7
A10AC01
ATC
insulin (human); parenteral
8.5
30.0
41
54
A07EC02
ATC
mesalazine; oral, rectal
29.3
29.2
39
15
104
Kela drug reimbursment
Thyroid insufficiency
12.1
28.9
30
27
H02AB07
ATC
prednisone; oral
4.8
28.7
76
193
UJF30
NOMESCO Finland
Ileoscopy through colon
5.1
26.5
64
150
L04AD02
ATC
tacrolimus; systemic
101.9
26.1
28
*
ZX120
NOMESCO Finland
Intravenous
4.9
23.4
57
134
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
43.6
23.1
28
7
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
246.7
22.9
23
*
A02BC02
ATC
pantoprazole; systemic
3.8
21.8
261
1686
L04AD01
ATC
ciclosporin; systemic
35.2
20.5
26
8
K90.0
ICD-10 Finland
Coeliac disease
38.5
20.1
25
7
UJF32
NOMESCO Finland
Coloscopy
3.2
19.4
105
427
R94.5
ICD-10 Finland
Abnormal results of liver function studies
17.6
18.7
29
18
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
17.6
18.7
29
18
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.9
18.6
44
100
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
24.5
18.0
25
11
JJA20
NOMESCO Finland
Open biopsy of liver
70.7
17.9
20
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.5
16.3
65
217
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
26.1
16.2
22
9
A10AB05
ATC
insulin aspart; parenteral
5.6
15.7
31
60
E03
ICD-10 Finland
Other hypothyroidism
15.8
15.6
25
17
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
12.1
15.6
28
25
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
47.4
15.2
18
*
C03DA01
ATC
spironolactone; oral
3.6
14.9
54
169
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
84.0
14.7
16
*
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
+∞
14.7
14
*
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
156.8
14.6
15
*
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
44.6
14.2
17
*
Z94.4
ICD-10 Finland
Liver transplant status
55.9
13.9
16
*
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
13.6
13
*
JJC00
NOMESCO Finland
Allogenic transplantation of liver
145.9
13.6
14
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
12.9
159
939
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
5.8
12.8
24
44
K50.8
ICD-10 Finland
Other Crohn disease
+∞
12.6
12
*
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
+∞
12.6
12
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
12.4
85
382
K51.8
ICD-10 Finland
Other ulcerative colitis
+∞
11.5
11
*
K50.0
ICD-10 Finland
Crohn disease of small intestine
+∞
11.5
11
*
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
9.7
11.2
22
24
L04AX03
ATC
methotrexate; systemic
5.7
10.5
20
37
N02AX02
ATC
tramadol; systemic, rectal
2.2
10.5
149
911
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
113.5
10.5
11
*
R18
ICD-10 Finland
Ascites
12.6
10.5
18
15
E03.89
ICD-10 Finland
Other specified hypothyroidism
16.7
10.5
16
10
A63.0
ICD-10 Finland
Anogenital (venereal) warts
5.0
10.4
23
49
K72.9
ICD-10 Finland
Hepatic failure, unspecified
33.7
10.4
13
*
127
Kela drug reimbursment
Transplant complication
24.3
10.3
14
6
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
4.0
9.8
29
78
R50.9
ICD-10 Finland
Fever, unspecified
2.7
9.7
60
254
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
102.9
9.5
10
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.9
9.5
47
177
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
+∞
9.4
9
*
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
+∞
9.4
9
*
5714B
ICD-9 Finland
Chronic liver disease and cirrhosis, Chronic hepatitis[HEPATITIS CHRONICA ACTIVA (HBSAG-)]
+∞
9.4
9
*
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
+∞
9.4
9
*
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.8
9.4
50
196
Z2221
NOMESCO Finland
Medical doctor
2.2
9.1
107
602
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.7
9.0
52
212
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
8.9
138
860
UJK02
NOMESCO Finland
ERCP
8.0
8.8
19
25
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.3
8.6
34
112
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.0
8.5
25
67
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
+∞
8.4
8
*
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
+∞
8.4
8
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
15.0
8.3
13
9
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
34.3
8.1
10
*
D97
ICPC
Liver disease NOS
22.7
8.1
11
5
H02AB09
ATC
hydrocortisone; systemic
8.0
7.5
16
21
K75.2
ICD-10 Finland
Nonspecific reactive hepatitis
81.9
7.4
8
*
K51
ICD-10 Finland
Ulcerative colitis
81.9
7.4
8
*
ZXE00
NOMESCO Finland
One hour or less
1.9
7.4
137
894
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
7.4
56
260
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
+∞
7.3
7
*
K74.5
ICD-10 Finland
Biliary cirrhosis, unspecified
+∞
7.3
7
*
K73.8
ICD-10 Finland
Other chronic hepatitis, not elsewhere classified
+∞
7.3
7
*
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
7.3
7
*
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
+∞
7.3
7
*
K71.2
ICD-10 Finland
Toxic liver disease with acute hepatitis
+∞
7.3
7
*
XW000
NOMESCO Finland
Bone marrow biopsy
4.7
7.3
17
38
M13.9
ICD-10 Finland
Arthritis, unspecified
3.3
7.0
27
87
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
6.6
51
238
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
6.5
77
428
B19.9
ICD-10 Finland
Unspecified viral hepatitis without hepatic coma
71.2
6.4
7
*
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
71.2
6.4
7
*
K74.0
ICD-10 Finland
Hepatic fibrosis
71.2
6.4
7
*
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
6.8
6.4
15
23
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.4
6.4
23
71
WX402
NOMESCO Finland
General anaesthesia
2.0
6.4
77
430
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.6
6.4
38
157
R74.8
ICD-10 Finland
Abnormal levels of other serum enzymes
4.0
6.3
18
47
K75.8
ICD-10 Finland
Other specified inflammatory liver diseases
+∞
6.3
6
*
K50.1
ICD-10 Finland
Crohn disease of large intestine
+∞
6.3
6
*
K73.89
ICD-10 Finland
Other long-term hepatitis, not classified differently
+∞
6.3
6
*
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
27.2
6.3
8
*
J01MA02
ATC
ciprofloxacin; systemic
1.8
6.2
120
786
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
4.3
6.2
16
39
A06AD11
ATC
lactulose; oral
2.3
6.0
46
214

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
167
23
148.78
307.65
1.4
1.3
—
—
—
0
0
176
49
77.44
301.31
1.8
1.2
782.22
—
titre
—
18
0
204
122
43.45
269.81
2.3
1.5
1.50
1.59
g/l
0.10
199
111
233
206
37.71
254.81
6.7
1.9
0.20
0.22
g/l
1.86
227
197
97
19
72.44
174.53
2.0
1.3
—
—
titre
—
0
0
207
275
19.08
168.37
2.4
1.2
812.57
335.65
titre
4.34
105
46
90
37
33.30
131.86
1.1
1.1
—
—
—
0
0
89
41
29.55
124.82
1.2
1.1
—
—
—
0
0
178
286
12.59
120.68
6.8
3.1
19.21
8.91
umol/l
2.34
170
244
158
257
11.05
104.23
1.5
1.4
—
—
—
0
0
214
502
10.61
102.58
2.4
1.3
2.94
2.21
g/l
5.57
194
297
73
33
28.26
102.39
1.3
1.7
279.56
233.58
u/ml
0.33
32
19
316
1309
58.32
102.13
21.3
6.1
17.90
10.58
umol/l
4.59
316
1235
176
359
9.54
94.42
1.5
1.6
—
—
—
0
0
74
45
21.02
91.16
1.2
1.4
—
—
—
0
0
91
8
157.40
89.35
1.2
1.0
—
—
—
0
0
148
273
9.14
85.83
2.2
1.8
30.46
23.76
%
2.96
141
238
85
75
15.01
85.53
1.4
1.5
—
—
—
0
0
293
1116
17.99
84.75
20.0
4.2
—
—
—
0
0
85
8
143.39
82.58
1.2
1.0
—
—
—
0
0
66
39
21.00
82.11
1.2
1.3
118.00
119.75
u/ml
—
9
8
298
1188
19.80
81.37
20.3
3.9
0.53
0.55
e9/l
0.82
278
1017
298
1191
19.72
81.06
20.4
3.9
0.04
0.04
e9/l
0.70
278
1014
298
1230
18.73
77.08
20.5
4.0
1.72
1.95
e9/l
1.76
283
1087
298
1245
18.37
75.60
20.9
4.4
0.16
0.18
e9/l
1.07
282
1083
276
1085
11.42
73.30
15.7
11.1
1.13
1.15
inr
0.36
112
318
122
232
7.83
67.08
1.4
1.4
—
—
—
0
0
254
1000
8.13
64.24
3.8
2.0
75.81
76.43
nmol/l
0.13
248
882
52
34
18.03
61.06
1.1
1.2
—
—
—
0
0
93
150
8.29
58.84
1.3
1.3
—
—
—
0
0
299
1456
14.65
58.26
24.2
7.8
3.55
3.95
e9/l
2.68
283
1253
317
1974
29.03
53.21
32.6
6.3
100.78
78.60
u/l
6.67
317
1832
40
22
20.60
50.74
1.3
1.2
—
—
—
0
0
85
154
7.13
47.70
6.1
3.6
0.26
0.93
%
1.76
34
47
83
151
7.05
46.31
7.0
3.8
0.03
0.05
%
0.17
32
39
89
174
6.67
46.26
6.8
3.5
0.54
1.07
%
1.43
40
60
246
1151
5.72
44.69
25.1
7.6
0.00
0.00
e9/l
0.56
219
910
100
231
5.82
43.40
3.9
2.2
39.84
30.52
u/l
1.45
91
191
56
76
8.70
40.34
2.2
1.1
3.84
—
u/ml
—
7
0
184
729
4.53
40.31
4.3
3.1
7.40
7.40
ph
0.51
38
135
81
165
6.21
40.00
7.1
3.6
0.03
0.20
%
1.22
31
51
48
56
9.89
38.89
1.4
1.1
—
—
—
0
0
242
1200
5.02
38.52
7.3
5.4
1.22
1.22
mmol/l
0.35
210
1024
162
604
4.36
38.09
1.5
1.2
1.35
0.67
u/ml
1.31
42
161
296
1749
9.01
37.42
10.4
2.9
105.15
45.47
u/l
9.97
291
1628
163
642
4.10
34.83
15.4
6.7
—
—
—
0
0
302
1919
9.45
32.32
10.5
3.0
18.68
11.16
mm/h
11.06
294
1745
218
1091
4.05
31.96
6.2
4.8
1.21
1.22
mmol/l
1.16
211
993
141
540
3.85
30.63
3.6
1.9
2.90
3.01
mg/l
0.24
130
453
43
59
8.25
30.44
1.8
1.1
19.74
5.45
u/ml
—
12
8
42
57
8.32
30.00
1.8
1.1
15.81
2.50
u/ml
—
10
7
91
292
3.94
24.95
3.5
1.3
186.63
77.94
ug/g
2.24
81
214
42
75
6.29
23.22
1.9
1.4
1.31
1.53
g/l
0.57
36
64
85
276
3.82
22.73
4.2
4.1
1.06
1.05
mmol/l
0.17
85
263
135
590
3.21
22.50
5.9
3.8
—
—
—
0
0
162
816
2.97
20.59
2.7
2.1
—
—
—
0
0
50
117
4.87
20.52
3.9
2.8
1295.77
1364.85
u/ml
0.01
44
101
25
31
8.66
19.02
5.9
3.0
57.52
59.23
%
0.20
25
31
226
1438
2.89
17.36
6.8
3.9
6.51
6.43
mmol/l
0.24
218
1334
318
2683
11.00
17.07
33.5
11.0
14.49
22.72
mg/l
9.40
295
2021
96
404
2.96
16.34
3.0
2.5
2.45
3.12
e6/l
0.20
51
195
87
347
3.06
16.28
1.2
1.1
—
—
—
0
0
200
1239
2.60
15.46
2.8
2.3
—
—
—
0
0
76
290
3.12
15.28
3.8
4.0
3.34
11.34
ug/l
2.63
52
240
47
134
3.93
14.81
1.6
2.5
—
—
—
0
0
141
759
2.52
14.45
3.8
2.7
16.52
133.50
e6/l
0.72
112
556
72
275
3.08
14.39
6.0
6.0
104.17
104.13
mmol/l
0.02
72
275
99
452
2.71
14.22
1.8
1.8
—
—
—
0
0
132
695
2.52
14.12
3.6
2.7
0.16
0.58
e6/l
2.58
103
494
155
882
2.45
13.96
4.5
3.1
29.37
66.53
e6/l
1.78
118
600
18
7
27.09
13.51
1.7
2.1
—
—
—
0
0
317
2747
8.12
13.48
28.4
12.8
138.96
139.88
mmol/l
8.20
317
2657
121
624
2.50
13.40
2.2
2.1
—
—
—
0
0
58
204
3.25
13.26
3.4
3.4
2.16
1.79
mmol/l
0.38
48
160
57
199
3.26
13.19
1.3
1.1
—
—
—
0
0
317
2756
7.95
13.09
28.6
12.8
3.88
3.95
mmol/l
5.58
317
2657
126
681
2.39
12.41
3.6
2.6
—
—
—
0
0
64
249
2.96
12.27
1.6
1.2
—
—
—
0
0
25
29
9.25
12.25
5.7
2.3
3.94
5.37
e9/l
1.03
25
29
47
152
3.45
12.25
2.8
2.3
70.78
75.16
e9/l
0.31
34
117
21
18
12.39
12.00
1.7
1.1
—
—
—
0
0
19
14
14.33
11.60
1.7
1.0
—
—
—
0
0
104
539
2.37
11.06
1.8
1.5
17.33
21.41
nmol/l
2.22
98
448
50
181
3.08
10.82
6.4
6.8
—
—
—
0
0
69
298
2.67
10.79
2.1
1.8
—
—
—
0
0
187
1254
2.16
10.36
4.6
3.3
0.00
0.00
estimate
0.50
44
239
94
479
2.36
10.29
3.0
2.6
533.92
540.76
mosm/kgh2o
0.10
88
411
187
1263
2.14
10.05
6.2
4.6
0.00
0.00
estimate
-0.00
44
228
150
936
2.12
9.89
2.2
1.8
93.93
97.70
pmol/l
0.44
81
436
87
440
2.34
9.62
3.8
3.2
180.77
246.02
ng/l
0.24
64
321
187
1280
2.09
9.50
4.9
3.3
0.00
0.01
estimate
0.50
41
221
27
71
4.06
9.44
3.0
3.1
—
—
—
0
0
318
2872
6.79
9.29
39.0
8.5
45.60
25.77
u/l
8.16
318
2757
132
806
2.08
9.02
3.4
3.0
—
—
—
0
0
13
7
19.27
9.00
5.2
1.6
—
—
—
0
0
15
12
13.04
8.95
1.8
1.9
10.13
10.77
umol/l
0.20
15
12
102
573
2.14
8.62
4.6
3.2
—
—
—
0
0
13
8
16.85
8.62
1.1
1.1
—
—
—
0
0
259
2049
2.32
8.54
4.8
2.8
15.07
14.55
pmol/l
2.75
245
1834
103
584
2.12
8.48
3.2
2.4
330.51
11917.08
umol/l
4.38
97
516
12
7
17.74
8.13
1.1
1.1
—
—
—
0
0
231
1769
2.07
7.96
5.5
3.8
—
—
—
0
0
125
786
1.96
7.59
1.6
1.4
—
—
—
0
0
160
1099
1.90
7.40
2.4
1.9
—
—
—
0
0
11
8
14.17
6.94
2.7
6.1
1251.73
1018.00
u/ml
—
11
8
29
99
3.12
6.89
2.2
1.9
—
—
—
0
0
15
21
7.43
6.78
1.0
1.1
—
—
—
0
0
11
10
11.33
6.34
1.4
2.6
668.73
390.50
e6/l
—
11
10
9
5
18.45
6.30
2.1
1.0
—
—
—
0
0
17
36
4.92
5.70
1.2
2.2
—
—
—
0
0
17
36
4.92
5.70
1.7
1.8
—
—
—
0
0
142
1001
1.75
5.57
4.4
3.2
5.65
5.85
ph
0.52
17
83
10
10
10.27
5.57
2.1
2.1
37570.00
37450.00
ug/l
—
10
10
8
5
16.34
5.43
1.0
1.0
—
—
—
0
0
8
5
16.34
5.43
1.0
1.4
—
—
—
0
0
10
11
9.34
5.32
1.3
4.8
52.49
36.09
%
—
10
11
20
64
3.26
5.28
4.2
2.0
—
—
—
0
0
126
869
1.74
5.27
4.1
3.4
2.35
2.37
mmol/l
0.53
117
772
13
22
6.11
5.27
2.8
1.3
0.84
1.11
g/l
1.78
13
22
36
161
2.39
5.14
2.2
2.8
74.91
70.72
ng/l
0.12
29
141
13
23
5.84
5.12
1.6
1.3
—
—
—
0
0
8
6
13.62
5.10
2.6
1.3
—
—
—
0
0
30
125
2.54
4.97
4.3
3.5
—
—
—
0
0
7
5
14.26
4.59
4.1
1.8
57.00
42.80
u/l
—
7
5
9
11
8.38
4.59
1.2
4.5
85.78
65.27
%
—
9
11
9
11
8.38
4.59
1.2
4.5
7.11
14.00
%
—
9
11
8
8
10.21
4.54
1.4
2.0
0.05
0.12
e9/l
—
8
8
15
37
4.20
4.46
1.4
5.3
—
—
—
0
0
23
90
2.67
4.32
1.3
1.2
—
—
—
0
0
71
438
1.80
4.26
1.3
1.2
21.91
23.96
iu/ml
0.13
29
130
75
472
1.77
4.21
4.5
2.8
2.48
2.45
mmol/l
1.18
69
415
28
123
2.40
4.17
2.9
2.3
0.08
0.15
e6/l
0.44
28
116
11
22
5.14
4.04
1.1
1.1
—
—
—
0
0
67
416
1.77
3.92
1.3
1.2
11.45
4.21
u/ml
0.54
22
147
268
2359
1.79
3.83
44.1
14.4
332.32
332.20
g/l
0.07
268
2346
25
110
2.38
3.72
3.4
3.0
4.29
4.46
pmol/l
0.37
25
101
100
702
1.61
3.68
2.7
2.7
6.94
7.43
mmol/l
0.50
87
595
20
80
2.60
3.62
2.8
2.9
0.31
0.13
g/l
0.75
11
27
34
173
2.08
3.59
3.3
2.3
118.45
159.39
ng/l
0.64
29
161
10
21
4.88
3.58
1.2
1.0
—
—
—
0
0
217
1824
1.57
3.57
3.7
3.5
—
—
—
0
0
50
294
1.83
3.49
1.6
1.4
—
—
—
0
0
33
169
2.06
3.43
3.8
2.3
—
—
—
0
0
12
32
3.85
3.42
1.7
1.3
—
—
—
0
0
20
83
2.50
3.37
1.1
1.2
110.83
231.94
miu/ml
—
6
40
274
2453
1.76
3.36
6.2
4.9
38.85
38.57
mmol/mol
0.21
268
2273
30
150
2.10
3.32
1.2
1.3
—
—
—
0
0
120
898
1.53
3.29
3.6
3.2
34.71
76.11
ng/l
0.47
82
585
16
60
2.75
3.28
1.3
1.4
278.75
311.27
ug/g
0.36
11
30
22
97
2.36
3.27
2.7
3.0
1.31
1.26
%
0.11
22
97
6
7
8.70
3.27
1.2
5.7
9.33
17.00
%
—
6
7
318
3042
3.45
3.20
50.7
16.5
235.32
254.70
e9/l
5.67
318
2952
318
3042
3.45
3.20
50.7
16.5
39.80
40.07
%
0.41
312
2859
318
3043
3.43
3.20
50.5
16.4
92.22
90.55
fl
7.10
318
2987
93
661
1.57
3.20
5.5
3.5
0.00
0.00
estimate
-0.00
40
219
41
234
1.86
3.15
8.8
6.3
0.49
1.28
mmol/l
0.53
31
197
6
8
7.61
3.06
4.8
2.3
1.25
2.07
umol/l
—
6
8
72
486
1.62
3.06
1.6
1.6
456.16
12407390.14
pmol/l
0.50
63
403
318
3046
3.37
3.06
51.1
16.6
133.07
134.95
g/l
1.64
318
2988
318
3044
3.41
3.05
50.8
16.5
6.37
6.51
e9/l
0.58
318
2942
318
3044
3.41
3.05
50.4
16.4
30.65
30.13
pg
4.35
318
2988
318
3044
3.41
3.05
50.7
16.5
4.38
4.50
e12/l
4.74
318
2941
60
387
1.68
3.04
1.8
1.6
1068.55
1243.37
nmol/l
0.92
50
276
38
214
1.88
3.04
4.0
3.3
—
—
—
0
0
7
12
5.94
3.03
1.1
1.0
—
—
—
0
0
7
12
5.94
3.03
1.6
1.0
—
—
—
0
0
84
591
1.57
3.00
2.1
1.7
2.22
1.12
mg/l
1.59
71
457
96
703
1.52
2.85
3.9
3.0
—
—
—
0
0
29
154
1.97
2.76
1.3
1.1
112.35
91.16
iu/ml
0.13
11
50
5
6
8.44
2.76
1.6
4.2
55.00
37.67
%
—
5
6
9
24
3.83
2.69
1.3
1.3
—
—
—
0
0
53
342
1.66
2.68
1.4
1.2
—
—
—
0
0
5
7
7.23
2.55
1.0
5.7
34.20
23.86
%
—
5
7
9
26
3.53
2.50
3.2
4.0
2.43
2.72
nmol/l
—
9
26
11
38
2.96
2.44
1.2
1.1
—
—
—
0
0
19
91
2.16
2.38
1.1
1.1
—
—
—
0
0
9
28
3.28
2.32
2.7
2.6
—
—
—
0
0
21
106
2.05
2.31
12.8
7.6
—
—
—
0
0
25
135
1.92
2.29
5.7
3.8
—
—
—
0
0
8
23
3.54
2.28
2.3
2.8
—
—
—
0
0
41
259
1.67
2.26
1.4
1.5
—
—
—
0
0
17
80
2.19
2.23
7.1
3.3
1.01
0.85
%
0.72
17
75
10
35
2.91
2.22
1.6
1.7
—
—
—
0
0
10
35
2.91
2.22
1.2
1.1
—
—
—
0
0
23
122
1.95
2.22
2.7
2.0
13.82
13.37
nmol/l
0.08
18
113
25
137
1.89
2.20
10.1
7.8
1.28
1.47
%
0.55
25
137
25
137
1.89
2.20
10.0
7.9
0.70
0.66
%
0.19
25
137
19
95
2.06
2.15
2.2
3.1
0.84
0.66
%
1.24
19
95
301
2842
1.83
2.12
25.0
10.4
—
—
—
0
0
14
62
2.31
2.10
3.9
4.5
4.11
3.83
mmol/l
0.88
14
62
83
627
1.44
2.05
2.7
2.9
1292.01
284.85
mg/l
0.58
48
383
9
32
2.86
2.01
1.8
3.1
—
—
—
0
0
285
2660
1.59
2.00
4.8
4.1
4.63
4.81
mmol/l
1.91
275
2464
275
2548
1.52
1.99
4.2
3.7
1.26
1.26
mmol/l
0.03
263
2336
7
21
3.38
1.97
1.9
3.8
—
—
—
0
0
7
21
3.38
1.97
1.1
1.6
—
—
—
0
0
5
11
4.60
1.95
1.0
1.0
—
—
—
0
0
14
273
0.49
1.88
1.1
1.4
—
—
—
0
0
86
666
1.40
1.84
3.2
3.4
7.08
9.88
mg/mmol
0.36
50
397
12
54
2.27
1.76
2.2
1.4
58.58
38.66
nmol/l
0.84
12
54
283
2654
1.52
1.75
4.6
4.1
1.49
1.53
mmol/l
0.75
271
2446
6
18
3.38
1.75
3.0
1.1
2.85
3.22
mg/l
—
6
18
8
30
2.71
1.73
1.3
1.1
—
—
—
0
0
7
25
2.84
1.66
1.4
1.1
301.00
263.08
pmol/l
—
7
25
23
136
1.74
1.64
3.1
3.9
7.45
7.42
ph
—
5
19
7
26
2.73
1.59
2.1
1.8
—
—
—
0
0
9
37
2.47
1.49
1.1
1.1
15.93
17.19
u/l
—
9
32
11
52
2.15
1.46
2.9
1.7
6.64
5.20
mmol/24h
1.07
11
46
9
40
2.28
1.41
8.8
4.3
10.89
10.46
mmol/l
—
9
35
9
40
2.28
1.41
8.8
4.4
103.00
106.94
mmol/l
—
9
35
21
127
1.70
1.40
2.9
2.0
—
—
—
0
0
286
2713
1.46
1.40
5.2
4.6
2.76
2.86
mmol/l
1.15
279
2498
6
23
2.64
1.37
1.2
1.1
—
—
—
0
0
5
17
2.97
1.36
4.6
3.8
70.20
89.24
nmol/l
—
5
17
16
91
1.80
1.31
1.1
1.2
—
—
—
0
0
15
85
1.80
1.25
4.2
4.2
—
—
—
0
0
11
57
1.96
1.18
4.6
2.7
2.61
1.56
mmol/l
0.54
11
57
34
243
1.45
1.15
1.4
1.4
—
—
—
0
0
7
30
2.36
1.13
2.1
1.7
34.71
32.17
pg
—
7
30
7
31
2.29
1.11
1.3
1.8
—
—
—
0
0
5
21
2.40
1.09
1.0
1.1
—
3.18
—
0
8
7
32
2.21
1.08
3.7
2.7
—
—
—
0
0
7
32
2.21
1.08
1.9
1.9
—
—
—
0
0
12
67
1.82
1.06
1.2
1.2
—
—
—
0
0
10
53
1.92
1.02
4.8
2.8
8.17
6.79
mmol/l
—
10
53
7
35
2.02
1.00
1.3
1.1
—
—
—
0
0
39
298
1.35
0.93
1.4
1.4
—
—
—
0
0
6
29
2.09
0.89
1.3
1.1
—
—
—
0
0
8
42
1.93
0.89
1.9
2.4
—
—
—
0
0
82
697
1.24
0.88
1.8
1.6
1.35
1.36
mmol/l
0.08
76
585
6
30
2.02
0.87
3.0
2.7
—
—
—
0
0
6
30
2.02
0.87
3.0
2.7
104.00
106.77
mmol/l
—
6
30
6
30
2.02
0.87
3.0
2.7
4.05
3.85
mmol/l
—
6
30
12
72
1.69
0.86
6.3
4.7
—
—
—
0
0
15
97
1.57
0.83
1.8
2.4
151.61
5016.55
u/l
—
8
43
66
552
1.25
0.82
6.0
3.6
1.02
1.02
kg/l
0.14
11
75
6
32
1.89
0.82
1.3
1.2
—
—
—
0
0
22
301
0.71
0.79
2.0
1.6
—
—
—
0
0
272
2613
1.26
0.77
4.9
4.3
5.76
5.78
mmol/l
0.11
266
2380
7
40
1.77
0.71
4.4
3.0
—
—
—
0
0
5
26
1.94
0.71
1.2
1.4
92.42
89.82
%
—
5
26
7
41
1.72
0.70
2.6
1.8
—
—
—
0
0
29
226
1.31
0.64
4.4
3.8
—
—
—
0
0
20
267
0.73
0.64
2.5
3.1
0.43
0.78
ug/l
3.14
11
171
6
105
0.56
0.62
1.2
1.3
—
—
—
0
0
25
192
1.33
0.61
2.0
2.2
5.91
4.98
ug/l
0.15
25
166
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
2.0
—
—
—
0
0
23
179
1.31
0.53
5.8
3.1
—
—
—
0
0
13
179
0.71
0.51
1.3
1.5
—
—
—
0
0
11
75
1.48
0.51
1.7
2.7
—
—
—
0
0
14
104
1.36
0.44
3.5
3.9
—
—
—
0
0
23
185
1.26
0.43
1.0
1.3
—
—
—
0
0
5
31
1.62
0.43
1.0
4.4
48.20
61.14
%
—
5
31
5
31
1.62
0.43
1.0
2.3
—
—
—
0
0
78
705
1.14
0.43
3.1
3.5
—
—
—
0
0
0
15
0.00
0.41
0.0
29.0
—
1845.73
—
0
15
0
15
0.00
0.41
0.0
16.3
—
913.53
—
0
15
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
14
108
1.31
0.36
1.0
1.1
—
—
—
0
0
9
121
0.74
0.36
1.3
1.6
—
—
—
0
0
6
46
1.31
0.33
1.0
2.7
—
—
—
0
0
7
93
0.75
0.22
1.1
1.8
—
—
—
0
0
5
42
1.19
0.21
1.2
1.1
—
—
—
0
0
5
42
1.19
0.21
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
31.00
—
0
5
0
10
0.00
0.21
0.0
1.3
—
52.10
—
0
10
0
13
0.00
0.21
0.0
1.2
—
62.21
—
0
7
6
48
1.25
0.20
1.0
3.9
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
11
132
0.83
0.18
1.8
1.4
—
—
—
0
0
10
121
0.82
0.18
1.3
1.6
—
—
—
0
0
10
121
0.82
0.18
1.3
1.6
—
—
—
0
0
10
120
0.83
0.17
1.3
1.6
—
—
—
0
0
6
78
0.76
0.15
1.2
1.9
—
—
—
0
0
47
445
1.07
0.12
3.7
5.0
0.97
3.20
ug/l
2.45
47
401
97
1000
0.96
0.11
3.1
2.6
—
—
—
0
0
6
57
1.05
0.08
1.3
1.9
—
—
—
0
0
5
65
0.77
0.08
1.2
1.2
—
—
—
0
0
7
64
1.10
0.08
1.1
1.1
—
—
—
0
0
7
64
1.10
0.08
1.6
1.7
3.86
3.61
mmol/l
—
7
59
24
254
0.94
0.06
1.5
1.7
—
—
—
0
0
10
110
0.91
0.05
1.3
1.7
—
—
—
0
0
17
180
0.94
0.04
1.1
1.4
—
—
—
0
0
11
112
0.98
0.00
1.5
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
6.4
—
0.29
—
0
8
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
7
71
0.99
-0.00
1.7
1.7
520.14
427.97
mg/l
—
7
66
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
137.75
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.0
—
0.48
—
0
8

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: AUTOHEP – Autoimmune hepatitis

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).