Autoimmune hepatitis

AUTOHEP

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K75.4
  • Cause of death: ICD-10 K75.4

2 out of 7 registries used, show all original rules.

276

4. Check minimum number of events

None

276

5. Include endpoints

None

276

6. Filter based on genotype QC (FinnGen only)

276

Control definitions (FinnGen only)

Control exclude
AUTOIMMUNE

Extra metadata

First used in FinnGen datafreeze
DF11

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 276 211 65
Unadjusted period prevalence (%) 0.06 0.07 0.03
Median age at first event (years) 61.14 62.41 57.02

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
240
Matched controls
2399
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K75.4
ICD-10 Finland
Autoimmune hepatitis
+∞
323.0
240
*
L04AX01
ATC
azathioprine; systemic
651.6
189.9
165
8
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
3418.7
167.4
142
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
262.5
145.6
137
12
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
97.6
128.6
137
32
A07EA06
ATC
budesonide; oral, local oral
297.8
118.5
112
7
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
106.7
65.2
69
9
H02AB06
ATC
prednisolone; systemic
12.7
63.4
199
662
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
+∞
55.4
51
*
A05AA02
ATC
ursodeoxycholic acid; oral
108.4
54.8
58
7
K76.9
ICD-10 Finland
Liver disease, unspecified
141.8
53.4
55
5
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
14.9
52.5
95
101
L01BB02
ATC
mercaptopurine; oral
275.3
45.6
45
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
6.4
38.8
148
484
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.7
32.4
123
375
K74.3
ICD-10 Finland
Primary biliary cirrhosis
+∞
32.0
30
*
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
81.4
31.8
35
5
H03AA01
ATC
levothyroxine sodium; systemic
9.2
30.9
70
103
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
32.9
30.0
39
14
L04AA06
ATC
mycophenolic acid; systemic
109.4
27.3
29
*
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
23.5
26.6
38
19
K51.5
ICD-10 Finland
Left sided colitis
+∞
26.5
25
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
24.4
23
*
A07EC02
ATC
mesalazine; oral, rectal
39.3
22.6
28
8
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
29.7
21.9
29
11
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.8
21.5
67
149
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
31.4
21.5
28
10
K83.0
ICD-10 Finland
Cholangitis
39.6
20.3
25
7
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
+∞
19.0
18
*
P01BA02
ATC
hydroxychloroquine; oral
13.0
16.6
29
25
L04AD01
ATC
ciclosporin; systemic
36.1
16.0
20
6
A02BC02
ATC
pantoprazole; systemic
3.4
16.0
182
1157
R94.5
ICD-10 Finland
Abnormal results of liver function studies
28.6
15.9
21
8
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
91.1
15.8
17
*
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
170.6
15.7
16
*
H02AB07
ATC
prednisone; oral
4.8
15.7
56
142
K90.0
ICD-10 Finland
Coeliac disease
38.7
14.7
18
5
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
10.4
14.4
28
30
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
21.7
14.0
20
10
UJF30
NOMESCO Finland
Ileoscopy through colon
5.2
12.9
41
91
ZX120
NOMESCO Finland
Intravenous
5.1
12.8
42
96
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
73.8
12.7
14
*
104
Kela drug reimbursment
Thyroid insufficiency
10.9
12.3
23
23
UJF32
NOMESCO Finland
Coloscopy
3.1
12.1
81
341
E03
ICD-10 Finland
Other hypothyroidism
14.6
11.7
19
14
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
+∞
11.5
11
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
12.8
11.0
19
16
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
22.7
10.8
15
7
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
114.8
10.5
11
*
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
+∞
10.5
10
*
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
10.5
10
*
K50.0
ICD-10 Finland
Crohn disease of small intestine
+∞
10.5
10
*
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
9.8
10.2
20
22
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
27.3
9.9
13
5
Z94.4
ICD-10 Finland
Liver transplant status
57.3
9.7
11
*
JJA20
NOMESCO Finland
Open biopsy of liver
57.3
9.7
11
*
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
31.4
9.5
12
*
JJC00
NOMESCO Finland
Allogenic transplantation of liver
103.9
9.5
10
*
K50.8
ICD-10 Finland
Other Crohn disease
+∞
9.4
9
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.4
9.2
47
161
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
5.9
9.2
25
46
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.9
9.0
29
65
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
8.2
8.8
19
25
N02AX02
ATC
tramadol; systemic, rectal
2.3
8.8
106
606
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
93.2
8.5
9
*
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
+∞
8.4
8
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
+∞
8.4
8
*
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
3.1
7.7
43
157
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.7
7.6
33
99
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
7.3
54
234
UJF92
NOMESCO Finland
Capsular endoscopy
31.0
7.2
9
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.8
7.2
48
197
M13.9
ICD-10 Finland
Arthritis, unspecified
5.0
6.9
21
45
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
3.0
6.5
37
136
E03.89
ICD-10 Finland
Other specified hypothyroidism
9.6
6.4
12
13
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
6.3
6
*
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
27.5
6.3
8
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
140
19
148.51
274.32
1.5
1.1
—
—
—
0
0
200
170
40.09
224.08
6.8
2.0
0.2
0.2
g/l
0.94
195
162
82
15
77.35
149.33
2.0
1.4
—
—
titre
—
0
0
176
240
18.48
140.24
2.4
1.3
779.3
311.8
titre
4.08
91
44
154
233
13.69
110.38
7.0
2.6
18.4
8.7
umol/l
1.93
148
192
73
31
31.66
105.42
1.1
1.0
—
—
—
0
0
73
35
28.00
100.54
1.2
1.1
—
—
—
0
0
269
1122
56.13
86.15
22.0
5.7
17.0
10.4
umol/l
3.52
269
1057
58
23
31.66
85.17
1.3
1.9
293.7
204.8
u/ml
—
27
9
131
221
10.38
83.31
1.5
1.4
—
—
—
0
0
212
635
11.09
79.21
17.3
3.8
—
—
—
0
0
176
437
9.36
78.42
2.4
1.5
2.9
2.2
g/l
4.82
161
260
60
33
22.95
77.31
1.3
1.5
—
—
—
0
0
146
312
8.81
74.24
1.5
1.5
—
—
—
0
0
72
5
193.69
71.89
1.2
1.0
—
—
—
0
0
254
1013
19.91
69.44
20.6
3.8
0.5
0.6
e9/l
1.82
237
868
254
1016
19.82
69.12
20.7
3.8
0.0
0.0
e9/l
0.53
237
866
68
61
14.47
67.51
1.4
1.5
—
—
—
0
0
121
236
8.35
65.99
2.1
1.8
29.2
23.6
%
2.02
115
209
254
1050
18.80
65.66
20.7
3.9
1.7
2.0
e9/l
1.70
242
928
66
5
172.53
65.14
1.1
1.0
—
—
—
0
0
254
1063
18.43
64.39
21.2
4.3
0.2
0.2
e9/l
2.04
241
927
216
789
8.99
61.54
11.9
7.1
1.1
1.1
inr
0.23
83
231
104
191
8.13
59.32
1.5
1.4
—
—
—
0
0
254
1238
14.19
49.38
24.7
7.8
3.6
4.0
e9/l
1.83
241
1067
78
126
8.24
49.26
1.3
1.3
—
—
—
0
0
43
33
15.25
46.18
1.1
1.2
—
—
—
0
0
36
20
20.55
45.46
1.3
1.2
—
—
—
0
0
270
1683
28.78
45.44
33.2
6.1
98.8
78.6
u/l
4.86
270
1560
210
975
5.83
38.89
25.6
7.8
0.0
0.0
e9/l
0.53
189
770
85
194
5.89
37.48
3.5
2.0
37.0
30.5
u/l
1.58
76
161
70
134
6.66
37.06
6.4
3.9
0.2
0.4
%
0.95
17
27
159
612
4.77
36.91
4.2
3.2
7.4
7.4
ph
0.81
34
110
69
132
6.64
36.52
7.3
4.1
0.0
0.0
%
0.00
21
30
73
151
6.21
35.62
7.2
3.8
0.6
0.8
%
0.41
25
42
50
69
8.63
35.59
2.1
1.2
4.3
—
u/ml
—
6
0
206
1011
5.09
33.62
7.2
5.6
1.2
1.2
mmol/l
0.47
177
865
143
539
4.43
33.39
15.3
6.6
—
—
—
0
0
253
1512
9.08
31.30
10.4
2.8
104.1
45.8
u/l
7.63
248
1413
187
911
4.26
29.32
6.1
4.6
1.2
1.2
mmol/l
1.49
182
828
65
145
5.56
28.87
7.6
3.9
0.0
0.1
%
0.65
22
37
257
1623
9.48
28.04
10.7
3.0
18.1
11.0
mm/h
8.72
250
1475
123
462
4.00
27.88
3.6
1.8
3.0
3.1
mg/l
0.06
114
387
132
527
3.88
27.24
1.5
1.2
1.2
0.7
u/ml
0.87
37
142
36
49
8.30
25.66
1.4
1.1
—
—
—
0
0
84
259
4.22
24.76
3.7
1.3
182.8
97.6
ug/g
1.24
73
185
116
490
3.36
20.85
12.4
3.1
—
—
—
0
0
32
49
7.26
20.49
1.8
1.1
21.9
2.8
u/ml
—
7
6
74
239
3.86
20.06
13.3
20.2
1.3
1.3
inr
0.09
19
32
142
692
3.17
19.81
2.7
2.2
—
—
—
0
0
72
233
3.83
19.42
4.4
4.1
1.1
1.0
mmol/l
0.22
72
220
43
95
5.18
18.96
3.6
3.0
1537.5
1656.2
u/ml
0.02
37
83
23
26
9.56
18.81
5.9
2.2
3.9
5.5
e9/l
1.01
23
26
23
27
9.20
18.28
6.1
2.7
56.3
59.6
%
0.40
23
27
85
329
3.29
17.18
2.9
2.5
2.4
3.4
e6/l
0.30
47
158
109
493
3.00
16.78
6.2
3.6
—
—
—
0
0
193
1215
2.96
15.49
6.6
3.6
6.5
6.4
mmol/l
0.23
185
1124
16
14
12.07
15.45
1.7
1.0
—
—
—
0
0
33
69
5.30
15.40
1.9
1.3
1.3
1.6
g/l
0.98
28
61
175
1051
2.82
15.30
4.2
3.7
—
—
—
0
0
14
11
13.35
14.36
1.6
2.0
10.1
10.6
umol/l
0.12
14
11
18
6
31.93
14.06
1.7
2.0
—
—
—
0
0
74
299
3.02
13.57
1.3
1.2
—
—
—
0
0
270
2292
9.19
13.55
34.4
10.8
14.2
22.5
mg/l
8.57
250
1735
122
645
2.60
13.27
3.7
2.7
15.6
160.8
e6/l
0.79
98
480
114
587
2.61
13.05
3.6
2.6
0.2
0.5
e6/l
2.47
88
422
64
245
3.10
12.84
3.9
4.2
3.5
12.3
ug/l
2.33
45
202
105
525
2.61
12.71
2.1
2.1
—
—
—
0
0
49
164
3.42
12.23
3.6
3.7
2.2
2.0
mmol/l
0.22
38
122
132
755
2.43
11.78
4.5
3.1
31.4
71.3
e6/l
1.58
103
512
14
15
9.78
11.75
2.1
1.1
—
—
—
0
0
50
174
3.29
11.70
3.8
3.7
—
—
—
0
0
41
126
3.65
11.62
2.5
2.1
71.0
74.2
e9/l
0.19
29
95
109
576
2.47
11.54
3.6
2.5
—
—
—
0
0
44
143
3.47
11.46
5.8
6.4
—
—
—
0
0
269
2327
7.15
11.24
29.0
12.5
139.0
139.9
mmol/l
5.83
269
2252
269
2335
6.99
10.87
29.2
12.6
3.9
3.9
mmol/l
5.72
269
2253
26
61
4.60
10.55
3.3
3.5
—
—
—
0
0
37
114
3.59
10.42
1.5
2.5
—
—
—
0
0
59
242
2.83
10.32
2.1
1.8
—
—
—
0
0
80
386
2.51
10.11
1.8
1.9
—
—
—
0
0
31
88
3.84
9.82
2.6
4.4
24.7
24.2
mmol/l
0.44
31
82
53
217
2.79
9.25
1.5
1.2
—
—
—
0
0
116
683
2.20
9.10
3.5
2.8
—
—
—
0
0
12
5
24.98
8.98
4.8
1.2
—
—
—
0
0
44
168
2.93
8.71
1.3
1.2
—
—
—
0
0
80
411
2.33
8.65
2.9
2.4
514.6
551.7
mosm/kgh2o
0.75
74
355
74
372
2.35
8.38
3.7
3.0
141.7
261.1
ng/l
0.50
54
264
90
495
2.21
8.21
4.9
3.2
—
—
—
0
0
12
17
7.33
8.06
2.3
1.2
0.8
1.2
g/l
1.60
12
17
156
1068
2.06
7.90
5.0
3.3
0.0
0.0
estimate
0.00
33
206
12
18
6.92
7.67
1.0
1.2
—
—
—
0
0
14
25
5.85
7.62
1.6
1.4
—
—
—
0
0
125
799
2.03
7.56
2.1
1.8
92.6
97.6
pmol/l
0.70
64
373
86
478
2.16
7.56
3.3
2.4
322.6
10070.2
umol/l
3.07
80
416
156
1081
2.02
7.50
6.7
4.5
0.0
0.0
estimate
0.00
36
204
270
2445
5.80
7.30
39.7
8.4
42.1
25.7
u/l
11.46
270
2352
155
1092
1.96
6.89
5.2
3.3
0.0
0.0
estimate
0.50
34
198
217
1747
2.13
6.27
4.9
2.9
15.1
14.5
pmol/l
2.81
205
1575
10
8
12.91
6.13
1.1
1.1
—
—
—
0
0
104
666
1.90
5.93
1.6
1.4
—
—
—
0
0
135
942
1.85
5.86
2.4
1.9
—
—
—
0
0
9
7
13.23
5.62
1.1
1.1
—
—
—
0
0
192
1514
1.88
5.44
5.5
3.8
—
—
—
0
0
109
729
1.82
5.30
4.0
3.2
2.4
2.4
mmol/l
0.31
102
637
8
7
11.72
4.81
1.3
5.3
84.4
70.0
%
—
8
7
234
2008
2.09
4.70
44.9
14.0
332.3
332.1
g/l
0.13
234
1998
7
5
14.31
4.60
2.0
1.4
—
—
—
0
0
27
112
2.56
4.55
4.5
3.3
—
—
—
0
0
24
94
2.70
4.52
2.3
2.0
—
—
—
0
0
16
53
3.14
4.03
2.6
2.1
—
—
—
0
0
23
94
2.58
4.00
3.6
3.1
4.3
4.5
pmol/l
0.35
23
85
10
24
4.29
3.92
1.1
1.2
—
—
—
0
0
20
77
2.72
3.90
2.8
3.2
1.3
1.3
%
0.04
20
77
49
278
1.93
3.88
1.4
1.2
—
—
—
0
0
37
190
2.09
3.85
8.0
5.6
1.0
1.4
mmol/l
0.19
26
156
58
350
1.83
3.80
1.3
1.2
9.7
4.6
u/ml
0.31
18
126
6
5
12.22
3.78
1.2
6.8
9.3
11.4
%
—
6
5
29
136
2.27
3.77
2.1
2.9
79.3
69.3
ng/l
0.24
22
122
28
130
2.28
3.72
1.2
1.3
—
—
—
0
0
9
16
5.77
3.69
2.7
2.3
—
—
—
0
0
24
106
2.38
3.57
2.5
2.3
0.1
0.1
e6/l
0.33
24
100
6
6
10.18
3.51
1.5
1.7
0.1
0.1
e9/l
—
6
6
75
501
1.68
3.44
2.1
1.8
1.9
0.9
mg/l
1.53
64
391
24
108
2.34
3.43
5.8
3.0
—
—
—
0
0
15
53
2.94
3.41
1.3
1.3
297.2
319.1
ug/g
—
10
28
59
372
1.75
3.32
1.3
1.2
16.5
26.5
iu/ml
0.89
24
108
184
1538
1.59
3.23
3.7
3.5
—
—
—
0
0
10
29
3.54
3.07
1.2
1.2
—
—
—
0
0
19
81
2.45
3.06
5.5
2.9
24.8
25.0
mmol/l
0.14
19
81
18
75
2.50
3.04
1.1
1.2
127.0
235.4
miu/ml
—
5
36
5
5
10.15
2.99
1.0
6.8
34.2
27.2
%
—
5
5
33
179
1.96
2.98
4.2
3.3
—
—
—
0
0
8
17
4.81
2.94
1.4
1.4
—
—
—
0
0
10
30
3.42
2.93
1.3
2.3
—
—
—
0
0
6
9
6.78
2.88
2.0
2.1
—
—
—
0
0
22
104
2.21
2.83
8.7
6.9
0.7
0.7
%
0.29
22
104
22
104
2.21
2.83
8.9
6.9
1.3
1.5
%
0.51
22
104
84
604
1.56
2.80
2.7
2.7
6.9
7.3
mmol/l
0.41
73
505
102
767
1.52
2.78
3.6
3.2
37.2
33.0
ng/l
0.10
69
496
61
408
1.64
2.74
1.7
1.7
446.9
444.7
pmol/l
0.02
54
338
8
19
4.30
2.70
2.4
3.1
—
—
—
0
0
79
566
1.55
2.66
6.0
3.5
0.0
0.0
estimate
0.00
32
198
18
82
2.28
2.53
11.9
6.4
—
—
—
0
0
8
21
3.89
2.48
2.8
2.7
—
—
—
0
0
8
21
3.89
2.48
3.5
4.1
2.6
2.7
nmol/l
—
8
21
18
83
2.25
2.47
1.3
1.2
—
—
—
0
0
41
255
1.71
2.42
1.7
1.4
—
—
—
0
0
28
155
1.90
2.40
3.5
2.3
—
—
—
0
0
7
17
4.20
2.37
1.0
1.0
—
—
—
0
0
270
2591
2.93
2.37
51.7
16.3
238.1
255.3
e9/l
3.98
270
2517
15
66
2.35
2.29
4.2
3.4
—
—
—
0
0
7
18
3.96
2.26
1.3
1.1
—
—
—
0
0
7
18
3.96
2.26
1.3
1.1
—
—
—
0
0
7
18
3.96
2.26
1.3
1.1
—
—
—
0
0
7
18
3.96
2.26
1.3
1.1
—
—
—
0
0
270
2595
2.86
2.23
52.1
16.3
133.3
134.7
g/l
0.91
270
2547
270
2594
2.88
2.23
51.8
16.3
6.4
6.5
e9/l
0.36
270
2512
270
2593
2.90
2.23
51.5
16.2
30.6
30.1
pg
3.07
270
2547
270
2593
2.90
2.23
51.7
16.3
4.4
4.5
e12/l
2.91
270
2511
270
2592
2.92
2.22
51.5
16.2
92.0
90.5
fl
5.07
270
2546
35
214
1.73
2.20
1.4
1.5
—
—
—
0
0
7
20
3.56
2.07
1.3
1.3
—
—
—
0
0
8
26
3.14
2.03
1.6
1.4
—
—
—
0
0
234
2150
1.58
2.00
37.9
11.9
39.5
39.8
%
0.18
194
1629
7
21
3.39
1.98
2.1
1.3
34.7
32.2
pg
—
7
21
15
71
2.18
1.96
7.6
3.8
1.0
0.8
%
0.79
15
66
9
33
2.78
1.95
1.1
5.5
—
—
—
0
0
48
329
1.56
1.95
1.7
1.6
1155.9
1225.3
nmol/l
0.26
40
230
0
53
0.00
1.89
0.0
1.7
—
—
—
0
0
24
140
1.78
1.78
1.2
1.2
118.6
109.9
iu/ml
—
10
52
16
82
2.01
1.73
1.1
1.0
—
—
—
0
0
7
24
2.96
1.73
1.9
1.8
—
—
—
0
0
71
541
1.42
1.71
2.6
2.9
1540.5
341.6
mg/l
0.57
40
317
256
2426
1.76
1.67
25.3
10.3
—
—
—
0
0
77
600
1.39
1.63
4.2
3.0
—
—
—
0
0
8
32
2.54
1.61
9.6
3.2
10.6
10.1
mmol/l
—
8
27
8
32
2.54
1.61
1.3
1.1
—
—
—
0
0
8
32
2.54
1.61
9.6
3.2
103.0
107.0
mmol/l
—
8
27
7
26
2.73
1.59
1.3
1.8
—
—
—
0
0
6
20
3.04
1.59
1.2
1.6
—
—
—
0
0
8
33
2.47
1.55
1.8
1.7
—
—
—
0
0
5
15
3.37
1.53
3.4
1.1
2.7
3.4
mg/l
—
5
15
5
15
3.37
1.53
4.6
3.9
70.2
92.8
nmol/l
—
5
15
13
240
0.52
1.52
1.1
1.4
—
—
—
0
0
7
27
2.63
1.52
1.9
2.6
—
—
—
0
0
6
22
2.76
1.44
1.2
1.1
—
—
—
0
0
73
576
1.36
1.42
3.4
3.5
7.0
11.2
mg/mmol
0.48
41
333
7
29
2.45
1.40
1.3
1.2
—
—
—
0
0
240
2260
1.47
1.37
4.8
4.1
4.7
4.8
mmol/l
1.46
232
2100
239
2255
1.45
1.28
4.5
4.0
1.5
1.5
mmol/l
1.23
231
2088
231
2170
1.40
1.24
4.1
3.7
1.3
1.2
mmol/l
0.15
221
2002
13
71
1.87
1.21
3.2
2.8
0.3
0.1
g/l
—
8
24
6
26
2.34
1.19
1.3
1.2
—
—
—
0
0
0
35
0.00
1.16
0.0
1.5
—
0.3
—
0
27
5
20
2.53
1.15
1.2
1.5
92.4
89.9
%
—
5
20
10
53
1.92
1.02
1.2
1.2
—
—
—
0
0
22
149
1.52
0.99
6.1
3.0
—
—
—
0
0
9
51
1.79
0.95
5.1
3.0
3.0
1.5
mmol/l
—
9
51
25
177
1.45
0.92
4.6
2.9
28.8
54.8
u/ml
0.59
25
172
71
593
1.27
0.92
1.8
1.6
1.4
1.4
mmol/l
0.32
65
502
11
63
1.78
0.91
6.6
4.5
—
—
—
0
0
241
2306
1.36
0.91
5.1
4.6
2.8
2.9
mmol/l
0.79
235
2128
13
204
0.62
0.90
2.2
3.0
0.4
0.8
ug/l
—
6
130
8
44
1.84
0.86
2.1
1.4
45.3
37.4
nmol/l
—
8
44
22
156
1.45
0.82
1.0
1.2
—
—
—
0
0
8
47
1.72
0.81
5.4
3.1
8.9
6.8
mmol/l
—
8
47
57
471
1.26
0.80
6.5
3.4
1.0
1.0
kg/l
—
9
63
13
82
1.61
0.79
1.1
1.1
—
—
—
0
0
6
33
1.84
0.79
3.7
3.3
—
—
—
0
0
6
34
1.78
0.77
1.0
2.5
—
—
—
0
0
13
83
1.59
0.76
2.0
2.5
66.3
5832.1
u/l
—
7
35
5
24
2.10
0.75
1.2
1.1
—
—
—
0
0
6
106
0.56
0.74
1.5
1.5
—
—
—
0
0
7
39
1.82
0.73
1.3
1.3
0.7
0.9
nmol/l
—
7
32
5
25
2.02
0.73
3.2
2.6
4.1
3.9
mmol/l
—
5
25
5
25
2.02
0.73
3.2
2.6
103.2
107.1
mmol/l
—
5
25
5
25
2.02
0.73
3.2
2.6
—
—
—
0
0
16
109
1.50
0.72
3.2
2.1
—
—
—
0
0
7
40
1.77
0.72
2.6
1.8
—
—
—
0
0
10
156
0.63
0.69
1.3
1.4
—
—
—
0
0
5
28
1.80
0.66
1.0
2.4
—
—
—
0
0
21
155
1.38
0.65
2.0
2.3
3.3
4.6
ug/l
0.46
21
134
231
2222
1.24
0.64
4.6
4.2
5.8
5.8
mmol/l
0.04
226
2038
0
20
0.00
0.60
0.0
1.3
—
1.9
—
0
12
8
122
0.65
0.56
1.8
1.4
—
—
—
0
0
6
39
1.55
0.53
1.0
2.9
—
—
—
0
0
7
106
0.65
0.49
1.4
1.4
—
—
—
0
0
7
106
0.65
0.49
1.4
1.4
—
—
—
0
0
7
106
0.65
0.49
1.4
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
2.1
—
—
—
0
0
30
253
1.21
0.38
1.5
1.4
—
—
—
0
0
65
587
1.14
0.38
3.1
3.5
—
—
—
0
0
7
97
0.71
0.31
1.4
1.5
—
—
—
0
0
24
205
1.19
0.28
1.2
1.4
—
—
—
0
0
8
67
1.20
0.26
2.0
2.7
—
—
—
0
0
19
224
0.84
0.26
1.5
1.6
—
—
—
0
0
22
189
1.18
0.25
4.2
4.0
—
—
—
0
0
5
40
1.25
0.22
1.0
4.0
—
—
—
0
0
0
11
0.00
0.21
0.0
18.2
—
938.5
—
0
11
0
11
0.00
0.21
0.0
27.3
—
2075.6
—
0
11
0
10
0.00
0.21
0.0
21.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
21
238
0.87
0.19
2.0
1.7
—
—
—
0
0
81
851
0.93
0.18
3.3
2.6
—
—
—
0
0
11
96
1.15
0.10
1.0
1.1
—
—
—
0
0
6
58
1.04
0.08
1.5
1.7
4.0
3.6
mmol/l
—
6
53
16
153
1.05
0.01
1.1
1.4
—
—
—
0
0
34
338
1.01
0.00
3.8
4.9
1.0
3.5
ug/l
1.91
34
308
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
6.5
—
0.5
—
0
8
5
59
0.84
0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
77.5
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
7.0
—
0.2
—
0
6
9
99
0.91
0.00
1.4
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
0.00
1.2
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
8
84
0.95
0.00
3.6
3.9
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
6
69
0.87
0.00
1.2
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
4.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AUTOHEP – Autoimmune hepatitis

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).