Social disorders starting during childhood or adolecense, excluding more controls

KRA_PSY_CHILDSOC_EXMORE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F94
  • Hospital discharge: ICD-9 3132C|3138X
  • Cause of death: ICD-10 F94
  • Cause of death: ICD-9 3132C|3138X

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
KRA_PSY_ANYMENTAL

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F90-F98
Name in latin
Perturbationes functionum socialium specialiter in pueritia incipientes

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9938 4269 5662
Only index persons 8179 3537 4642
Unadjusted period prevalence (%)
Whole population 0.14 0.12 0.16
Only index persons 0.16 0.13 0.18
Median age at first event (years)
Whole population 9.00 9.25 8.80
Only index persons 9.85 10.26 9.54

-FinnGen-

Key figures

All Female Male
Number of individuals 309 173 136
Unadjusted period prevalence (%) 0.06 0.06 0.06
Median age at first event (years) 11.27 12.22 10.05

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
286
Matched controls
2859
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N05AH04
ATC
quetiapine; oral
35.6
90.4
119
56
F94.0
ICD-10 Finland
Elective mutism
+∞
83.5
76
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
+∞
81.2
74
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
21.8
79.6
124
97
F94.8
ICD-10 Finland
Other childhood disorders of social functioning
+∞
75.4
69
*
N05AH03
ATC
olanzapine; systemic
475.6
74.4
71
*
N05AX08
ATC
risperidone; systemic
221.7
68.4
68
*
F94.9
ICD-10 Finland
Childhood disorder of social functioning, unspecified
+∞
67.4
62
*
F29
ICD-10 Finland
Unspecified nonorganic psychosis
+∞
60.6
56
*
N05AX12
ATC
aripiprazole; systemic
+∞
59.5
55
*
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
689.0
58.9
56
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
21.4
57.9
88
58
F94.1
ICD-10 Finland
Reactive attachment disorder of childhood
+∞
56.1
52
*
Z2445
NOMESCO Finland
Psychologist
32.1
53.5
71
29
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
+∞
51.6
48
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
92.3
48.9
53
7
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
+∞
46.1
43
*
ZY010
NOMESCO Finland
Hospital outpatient
30.1
46.1
62
26
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
26.4
43.7
61
29
F93.89
ICD-10 Finland
Other childhood emotional disorders
+∞
41.7
39
*
3138X
ICD-9 Finland
Disturbance of emotions specific to childhood and adolescence, Other or mixed emotional disturbances of childhood or adolescence[MUU MÄÄRITTELTY EMOTIONAALISENA OIREENA ILM. HÄIRIÖ]
+∞
41.7
39
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
88.3
41.3
45
6
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
+∞
39.5
37
*
Z2446
NOMESCO Finland
Social worker
11.7
39.3
77
87
N06AX16
ATC
venlafaxine; oral
16.8
39.1
64
48
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
119.1
38.9
41
*
F90.0
ICD-10 Finland
Disturbance of activity and attention
19.9
38.0
58
36
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
+∞
37.3
35
*
N06AB03
ATC
fluoxetine; oral
17.0
35.8
58
42
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
33.9
35.5
46
16
IGY99
NOMESCO Finland
Other psychiatric treatment contact
66.0
35.2
40
7
N03AG01
ATC
valproic acid; systemic, rectal
22.5
33.6
49
26
N05AH02
ATC
clozapine; systemic
+∞
32.9
31
*
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
10.0
32.6
69
88
F92.8
ICD-10 Finland
Other mixed disorders of conduct and emotions
+∞
31.9
30
*
F92.9
ICD-10 Finland
Mixed disorder of conduct and emotions, unspecified
+∞
31.9
30
*
N05BA01
ATC
diazepam; systemic, rectal
14.9
31.6
54
44
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
+∞
30.8
29
*
N06BA04
ATC
methylphenidate; oral
27.9
30.2
41
17
N06AB06
ATC
sertraline; oral
13.3
30.1
54
49
ZYC01
NOMESCO Finland
Remote contact by phone
18.7
29.7
46
29
N05AA02
ATC
levomepromazine; systemic
+∞
29.7
28
*
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
13.3
29.0
52
47
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
+∞
28.6
27
*
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
71.7
28.6
32
5
N05BA04
ATC
oxazepam; oral
7.0
27.9
75
138
N06AX11
ATC
mirtazapine; oral
6.3
27.6
82
172
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
69.2
27.6
31
5
IGV01
NOMESCO Finland
Psychiatric network contact
297.4
27.2
27
*
N03AX09
ATC
lamotrigine; oral
24.1
26.9
38
18
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
15.0
26.8
45
35
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
+∞
26.5
25
*
N05AF03
ATC
chlorprothixene; systemic
284.8
26.1
26
*
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
31.9
26.0
34
12
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
55.6
25.8
30
6
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
9.2
25.6
56
74
F83
ICD-10 Finland
Mixed specific developmental disorders
+∞
25.4
24
*
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
99.0
25.1
27
*
F84.5
ICD-10 Finland
Asperger syndrome
272.8
25.1
25
*
N06AB10
ATC
escitalopram; oral
5.6
25.0
81
187
R5599
NOMESCO Finland
Other rehabilitation service
38.4
24.8
31
9
Z3231
NOMESCO Finland
Registered nurse
4.2
24.6
118
410
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
28.5
24.6
33
13
F92.0
ICD-10 Finland
Depressive conduct disorder
+∞
24.3
23
*
F20.9
ICD-10 Finland
Schizophrenia, unspecified
+∞
24.3
23
*
N06AB04
ATC
citalopram; systemic
8.5
24.1
55
78
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
260.9
24.0
24
*
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
13.5
23.9
42
36
IGP01
NOMESCO Finland
Psychiatric family contact
59.3
23.5
27
5
IGY02
NOMESCO Finland
Psychiatric monitoring contact
26.6
22.7
31
13
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
10.9
22.5
44
47
F84.9
ICD-10 Finland
Pervasive developmental disorder, unspecified
+∞
22.2
21
*
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
+∞
22.2
21
*
F80.9
ICD-10 Finland
Developmental disorder of speech and language, unspecified
+∞
22.2
21
*
N06AX12
ATC
bupropion; oral
18.2
22.0
34
21
N05CF01
ATC
zopiclone; oral
6.6
22.0
60
110
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
237.3
21.9
22
*
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
13.5
21.2
37
31
F80.2
ICD-10 Finland
Receptive language disorder
+∞
21.1
20
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
10.3
21.0
42
47
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
25.7
20.4
28
12
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
38.9
20.2
25
7
Z61.8
ICD-10 Finland
Other negative life events in childhood
+∞
20.0
19
*
F80.1
ICD-10 Finland
Expressive language disorder
112.9
19.8
21
*
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
112.9
19.8
21
*
Z2221
NOMESCO Finland
Medical doctor
3.9
19.6
96
328
IEV99
NOMESCO Finland
Other psychiatric network intervention
+∞
19.0
18
*
P72
ICPC
Schizophrenia
+∞
19.0
18
*
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
+∞
19.0
18
*
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
+∞
19.0
18
*
Z3226
NOMESCO Finland
Physiotherapist
4.5
18.8
75
211
N05BE01
ATC
buspirone; oral
202.7
18.8
19
*
P29
ICPC
Psychological sympt/compl other
6.7
18.3
48
83
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
11.9
18.0
33
31
F60.9
ICD-10 Finland
Personality disorder, unspecified
+∞
17.9
17
*
F93.9
ICD-10 Finland
Childhood emotional disorder, unspecified
+∞
17.9
17
*
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
+∞
17.9
17
*
F82
ICD-10 Finland
Specific developmental disorder of motor function
191.3
17.7
18
*
F40.1
ICD-10 Finland
Social phobias
26.0
17.6
24
10
F41.1
ICD-10 Finland
Generalized anxiety disorder
10.1
17.5
35
39
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
9.2
17.1
36
44
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
+∞
16.8
16
*
N05AN01
ATC
lithium; oral
180.0
16.7
17
*
N05AB03
ATC
perphenazine; systemic, rectal
180.0
16.7
17
*
F43.1
ICD-10 Finland
Post-traumatic stress disorder
16.7
16.5
26
17
P74
ICPC
Anxiety disorder/anxiety state
8.9
16.4
35
44
N05BA06
ATC
lorazepam; systemic, sublingual
35.7
16.0
20
6
ZY000
NOMESCO Finland
Hospital inpatient
63.7
15.9
18
*
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
+∞
15.8
15
*
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
+∞
15.8
15
*
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
168.8
15.6
16
*
F99
ICD-10 Finland
Mental disorder, not otherwise specified
30.5
15.4
20
7
N06AB05
ATC
paroxetine; oral
17.7
15.0
23
14
ZXY82
NOMESCO Finland
Nurse in multidisciplinary team
+∞
14.7
14
*
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
+∞
14.7
14
*
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
+∞
14.7
14
*
F94.2
ICD-10 Finland
Disinhibited attachment disorder of childhood
+∞
14.7
14
*
R4140
NOMESCO Finland
Psychotherapy
+∞
14.7
14
*
Z63.8
ICD-10 Finland
Other specified problems related to primary support group
+∞
14.7
14
*
F88
ICD-10 Finland
Other disorders of psychological development
+∞
14.7
14
*
F50.9
ICD-10 Finland
Eating disorder, unspecified
157.7
14.6
15
*
P01
ICPC
Feeling anxious/nervous/tense
3.4
14.5
79
285
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
14.4
14.5
24
18
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
5.7
14.0
41
81
F41.8
ICD-10 Finland
Other specified anxiety disorders
11.8
13.8
25
23
N07BB01
ATC
disulfiram; oral
36.0
13.7
17
5
331
Kela drug reimbursment
Atomoxetine, dexamphetamine, guanfacine and lisdexamphetamine
146.6
13.6
14
*
XA800
NOMESCO Finland
Neuropsychological investigation
10.1
13.3
26
28
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.8
12.8
58
179
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
11.8
12.8
23
21
N03AE01
ATC
clonazepam; systemic
18.4
12.7
19
11
C07AA05
ATC
propranolol; systemic
3.8
12.7
57
175
P99
ICPC
Psychological disorders other
14.1
12.6
21
16
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
+∞
12.6
12
*
N04AA02
ATC
biperiden; systemic
+∞
12.6
12
*
F61.0
ICD-10 Finland
Mixed personality disorders
135.7
12.5
13
*
F10.09
ICD-10 Finland
Alcohol intoxication UNS
135.7
12.5
13
*
F39
ICD-10 Finland
Unspecified mood [affective] disorder
39.4
12.3
15
*
ZXE20
NOMESCO Finland
More than three and less than five hours
4.8
12.3
42
99
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
4.6
12.2
43
105
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
4.4
12.1
45
116
R56.8
ICD-10 Finland
Other and unspecified convulsions
6.1
12.1
33
60
R4120
NOMESCO Finland
Occupational therapy
7.7
11.8
27
38
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
67.8
11.7
13
*
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
24.1
11.7
16
7
P76
ICPC
Depressive disorder
6.0
11.6
32
59
N05AD01
ATC
haloperidol; systemic
+∞
11.5
11
*
ZXY80
NOMESCO Finland
Doctor in multidisciplinary team
+∞
11.5
11
*
IER01
NOMESCO Finland
Psychoeducation, group
+∞
11.5
11
*
F84.8
ICD-10 Finland
Other pervasive developmental disorders
+∞
11.5
11
*
ZXY03
NOMESCO Finland
Occupational therapist
+∞
11.5
11
*
IER02
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, group
+∞
11.5
11
*
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
+∞
11.5
11
*
AA400
NOMESCO Finland
Electroconvulsive therapy
+∞
11.5
11
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.7
11.4
90
410
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
13.5
11.3
19
15
IEP03
NOMESCO Finland
Focused parental counselling
21.1
11.3
16
8
F51.0
ICD-10 Finland
Nonorganic insomnia
4.1
11.2
45
125
C07AB07
ATC
bisoprolol; oral
4.0
11.0
46
132
IEP99
NOMESCO Finland
Other psychiatric family intervention
45.2
11.0
13
*
AA1AD
NOMESCO Finland
CT of head and brain
4.5
10.9
39
97
XF400
NOMESCO Finland
ECG with 12 standard connections
3.6
10.6
50
159
F93.1
ICD-10 Finland
Phobic anxiety disorder of childhood
114.0
10.5
11
*
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
114.0
10.5
11
*
Z3229
NOMESCO Finland
Other healthcare associate professional
4.9
10.5
34
76
ZXY49
NOMESCO Finland
Other health care provider
+∞
10.5
10
*
IBZ02
NOMESCO Finland
Somatic assessment of psychiatric patient
+∞
10.5
10
*
IDY03
NOMESCO Finland
Systematic individual therapy, cognitive-behavioural
+∞
10.5
10
*
F98.9
ICD-10 Finland
Unspecified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
+∞
10.5
10
*
Z61.1
ICD-10 Finland
Removal from home in childhood
+∞
10.5
10
*
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
+∞
10.5
10
*
F50.0
ICD-10 Finland
Anorexia nervosa
+∞
10.5
10
*
RS214
NOMESCO Finland
NA
+∞
10.5
10
*
R62.0
ICD-10 Finland
Delayed milestone
24.4
10.3
14
6
Z71.8
ICD-10 Finland
Other specified counselling
2.6
10.3
92
444
ZXE00
NOMESCO Finland
One hour or less
2.4
10.1
115
633
F32.8
ICD-10 Finland
Other depressive episodes
41.6
10.0
12
*
P24
ICPC
Specific learning problem
12.8
10.0
17
14
ZXD10
NOMESCO Finland
Scheduled procedure
2.5
10.0
100
513
SPAT1240
SPAT
Therapeutic discussion
3.2
9.9
55
198
ZXY01
NOMESCO Finland
Chief Physician, Head of Department or Deputy Chief Physician
57.0
9.7
11
*
F81.9
ICD-10 Finland
Developmental disorder of scholastic skills, unspecified
57.0
9.7
11
*
F80.8
ICD-10 Finland
Other developmental disorders of speech and language
57.0
9.7
11
*
Z29
ICPC
Social problem NOS
10.6
9.7
18
18
A02BC02
ATC
pantoprazole; systemic
2.3
9.5
110
604
IBZ06
NOMESCO Finland
Evaluation concerning developmental neuropsychiatry
103.3
9.5
10
*
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
103.3
9.5
10
*
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
103.3
9.5
10
*
N03AX16
ATC
pregabalin; oral
4.3
9.4
35
90
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
22.6
9.4
13
6
F21
ICD-10 Finland
Schizotypal disorder
+∞
9.4
9
*
F93.80
ICD-10 Finland
Generalized anxiety in the bardom age
+∞
9.4
9
*
ICC01
NOMESCO Finland
Psychiatric treatment plan, transfer to psychiatric outpatient clinic
+∞
9.4
9
*
3138C
ICD-9 Finland
Disturbance of emotions specific to childhood and adolescence, Other or mixed emotional disturbances of childhood or adolescence[LAPSUUSIÄN RAJATILAHÄIRIÖ]
+∞
9.4
9
*
ZXY60
NOMESCO Finland
2-person team, nurses
+∞
9.4
9
*
XA820
NOMESCO Finland
NA
+∞
9.4
9
*
IBB02
NOMESCO Finland
Psychiatric evaluation of working capacity and rehabilitation
+∞
9.4
9
*
A28
ICPC
Limited function/disability NOS
7.1
9.3
22
33
F41.09
ICD-10 Finland
UNS Panic Syndrome
12.0
9.2
16
14
P03
ICPC
Feeling depressed
3.2
9.1
50
177
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
19.4
9.0
13
7
ZXE21
NOMESCO Finland
Procedure duration at least 3 but less than 4 hours
24.9
9.0
12
5
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
6.5
8.8
22
36
N05CD07
ATC
temazepam; oral
14.6
8.8
14
10
Z63.5
ICD-10 Finland
Disruption of family by separation and divorce
51.6
8.7
10
*
N05BA12
ATC
alprazolam; oral
8.6
8.7
18
22
F90.9
ICD-10 Finland
Hyperkinetic disorder, unspecified
28.5
8.5
11
*
S10
ICPC
Boil/carbuncle
6.6
8.5
21
34
R11
ICD-10 Finland
Nausea and vomiting
3.8
8.5
36
105
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
13.3
8.5
14
11
F42.2
ICD-10 Finland
Mixed obsessional thoughts and acts
92.6
8.5
9
*
F89
ICD-10 Finland
Unspecified disorder of psychological development
92.6
8.5
9
*
N06BA12
ATC
lisdexamfetamine; oral
92.6
8.5
9
*
Z72.2
ICD-10 Finland
Drug use
92.6
8.5
9
*
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
92.6
8.5
9
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.0
8.4
33
90
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
+∞
8.4
8
*
3132C
ICD-9 Finland
Disturbance of emotions specific to childhood and adolescence, Sensitivity, shyness and social withdrawal disorder
+∞
8.4
8
*
F91.9
ICD-10 Finland
Conduct disorder, unspecified
+∞
8.4
8
*
F10.20
ICD-10 Finland
Alcohol dependence currently independent
+∞
8.4
8
*
N05AL01
ATC
sulpiride; systemic
+∞
8.4
8
*
F25.10
ICD-10 Finland
Schizoaffective syndrome, depressive type with only concomitant bipolar and schizophrenic symptoms
+∞
8.4
8
*
3153X
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[PUHEEN KEHITYKSEN ERITYISVAIKEUS]
+∞
8.4
8
*
N05AE04
ATC
ziprasidone; systemic
+∞
8.4
8
*
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
+∞
8.4
8
*
F64.9
ICD-10 Finland
Gender identity disorder, unspecified
+∞
8.4
8
*
ZXY81
NOMESCO Finland
Psychologist in multidisciplinary team
+∞
8.4
8
*
N05AA01
ATC
chlorpromazine; systemic, rectal
+∞
8.4
8
*
IFB01
NOMESCO Finland
Electroconvulsive Therapy (ECT)
+∞
8.4
8
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
6.0
8.3
22
39
T74.1
ICD-10 Finland
Physical abuse
9.3
8.1
16
18
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
17.8
8.1
12
7
N06AX22
ATC
agomelatine; oral
34.4
8.1
10
*
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
22.8
8.1
11
5
R05
ICPC
Cough
2.3
8.1
82
419
K04.5
ICD-10 Finland
Chronic apical periodontitis
2.9
8.0
52
204
S29
ICPC
Skin symptom/complaint other
2.7
7.9
58
247
R51.80
ICD-10 Finland
Headache
2.6
7.8
61
271
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.8
7.8
52
210
SPAT1365
SPAT
Health check-up performed during first study year due to special need in students of upper secondary schools or vocational schools
15.6
7.8
12
8
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
15.6
7.8
12
8
F42.0
ICD-10 Finland
Predominantly obsessional thoughts or ruminations
46.2
7.8
9
*
RL130
NOMESCO Finland
NA
46.2
7.8
9
*
A06AD11
ATC
lactulose; oral
4.4
7.7
27
66
EBA05
NOMESCO Finland
Complicated extraction of tooth
2.7
7.7
54
224
K59.09
ICD-10 Finland
Constipation, unspecified
6.1
7.7
20
35
Z01.8
ICD-10 Finland
Other specified special examinations
2.7
7.6
54
226
SPAT1396
SPAT
Meeting with multidisciplinary group of experts
9.2
7.6
15
17
F81.0
ICD-10 Finland
Specific reading disorder
25.8
7.6
10
*
F41.00
ICD-10 Finland
Moderate panic disorder
25.8
7.6
10
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
5.3
7.6
22
44
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
7.5
76
384
K02.1
ICD-10 Finland
Caries of dentine
2.1
7.5
199
1504
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.2
7.5
22
45
Z61.9
ICD-10 Finland
Negative life event in childhood, unspecified
82.1
7.5
8
*
IEY01
NOMESCO Finland
Psychoeducation, individual
82.1
7.5
8
*
Z10.1
ICD-10 Finland
Routine general health check-up of inhabitants of institutions
82.1
7.5
8
*
R4110
NOMESCO Finland
Physiotherapy
2.5
7.3
60
272
F20.04
ICD-10 Finland
Paranoid schizophrenia with partial recurrence
+∞
7.3
7
*
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
+∞
7.3
7
*
IAB08
NOMESCO Finland
Consultation concerning a patient who has attempted suicide
+∞
7.3
7
*
F20.09
ICD-10 Finland
Paranoid schizophrenia UNS
+∞
7.3
7
*
F84.0
ICD-10 Finland
Childhood autism
+∞
7.3
7
*
F20
ICD-10 Finland
Schizophrenia
+∞
7.3
7
*
X78
ICD-10 Finland
Intentional self-harm by sharp object
+∞
7.3
7
*
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
+∞
7.3
7
*
P18
ICPC
Medication abuse
+∞
7.3
7
*
3153A
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[KIELENKEHITYKSEN ERITYISVAIKEUS]
+∞
7.3
7
*
RT420
NOMESCO Finland
NA
+∞
7.3
7
*
F90.1
ICD-10 Finland
Hyperkinetic conduct disorder
+∞
7.3
7
*
F25.00
ICD-10 Finland
Schizoaffective syndrome, manic type with only simultaneous bipolar and schizophrenic symptoms
+∞
7.3
7
*
N06BA09
ATC
atomoxetine; oral
+∞
7.3
7
*
Z72.8
ICD-10 Finland
Other problems related to lifestyle
+∞
7.3
7
*
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
+∞
7.3
7
*
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
3.7
7.3
31
91
P15
ICPC
Chronic alcohol abuse
16.3
7.3
11
7
C03CA01
ATC
furosemide; systemic
5.9
7.2
19
34
F60.8
ICD-10 Finland
Other specific personality disorders
30.8
7.2
9
*
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
30.8
7.2
9
*
N06AX03
ATC
mianserin; oral
20.6
7.2
10
5
G40.9
ICD-10 Finland
Epilepsy, unspecified
9.1
7.1
14
16
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
10.4
7.1
13
13
F32
ICD-10 Finland
Depressive episode
5.1
7.0
21
44
D10
ICPC
Vomiting
2.7
7.0
47
191
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
7.0
6.9
16
24
E66.9
ICD-10 Finland
Obesity, unspecified
6.4
6.9
17
28
SPAT1243
SPAT
Psychiatric/psychological examination
5.0
6.9
21
45
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
6.9
70
352
EBA15
NOMESCO Finland
Extraction of large number of teeth
9.7
6.9
13
14
EBA00
NOMESCO Finland
Extraction of tooth
2.0
6.8
126
818
P27
ICPC
Fear of mental disorder
17.2
6.8
10
6
Z04.4
ICD-10 Finland
Examination and observation following alleged rape and seduction
41.0
6.8
8
*
RS140
NOMESCO Finland
NA
41.0
6.8
8
*
N06AX21
ATC
duloxetine; oral
5.4
6.8
19
37
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
9.0
6.6
13
15
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
5.3
6.6
19
38
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.1
6.6
24
62
SPAT1260
SPAT
Consultation of another employee
2.5
6.5
53
240
TPH07
NOMESCO Finland
Cathetrisation of artery
3.8
6.5
26
73
N03AX11
ATC
topiramate; oral
7.7
6.5
14
19
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
71.4
6.5
7
*
IBB01
NOMESCO Finland
Psychiatric functioning capacity evaluation
71.4
6.5
7
*
ZXY61
NOMESCO Finland
2-person team, special workers
71.4
6.5
7
*
ZYB04
NOMESCO Finland
Outreach service in patient’s home or everyday environment
71.4
6.5
7
*
F34.1
ICD-10 Finland
Dysthymia
14.7
6.4
10
7
L17
ICPC
Foot/toe symptom/complaint
2.2
6.3
73
392
N05CF02
ATC
zolpidem; oral
3.5
6.3
28
86
F23.99
ICD-10 Finland
Acute and transient psychosis, unspecified UNS
+∞
6.3
6
*
F98.02
ICD-10 Finland
Non-organic nocturnal and diurnal enuresis
+∞
6.3
6
*
F93.0
ICD-10 Finland
Separation anxiety disorder of childhood
+∞
6.3
6
*
ZXY59
NOMESCO Finland
2-person team, nurse-other special worker
+∞
6.3
6
*
IEY08
NOMESCO Finland
Psychiatric coaching, domestic and community skills
+∞
6.3
6
*
IEY02
NOMESCO Finland
Intensified psychiatric outpatient care, Assertive Community Treatment (ACT)
+∞
6.3
6
*
F91.3
ICD-10 Finland
Oppositional defiant disorder
+∞
6.3
6
*
F91.0
ICD-10 Finland
Conduct disorder confined to the family context
+∞
6.3
6
*
F19.21
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances currently independent but staying in a controlling environment
+∞
6.3
6
*
F44.9
ICD-10 Finland
Dissociative [conversion] disorder, unspecified
+∞
6.3
6
*
F20.08
ICD-10 Finland
Paranoid schizophrenia other definite
+∞
6.3
6
*
IAB07
NOMESCO Finland
Consultation concerning a patient with self-harm intention
+∞
6.3
6
*
IEY06
NOMESCO Finland
Psychiatric treatment and rehabilitation coaching
+∞
6.3
6
*
IEY19
NOMESCO Finland
Psychiatric health counselling and guidance
+∞
6.3
6
*
N05AF05
ATC
zuclopenthixol; systemic
+∞
6.3
6
*
3092E
ICD-9 Finland
Adjustment reaction, With predominant disturbance of other emotions[USEINA EMOTIONAALISINA OIREINA ILM.SOPEUTUMISHÄIRIÖ]
+∞
6.3
6
*
ZXY84
NOMESCO Finland
Occupational therapist in multidisciplinary team
+∞
6.3
6
*
P98
ICPC
Psychosis NOS/other
+∞
6.3
6
*
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
+∞
6.3
6
*
F10.24
ICD-10 Finland
Alcohol depence active use
+∞
6.3
6
*
F31
ICD-10 Finland
Bipolar affective disorder
+∞
6.3
6
*
ZXY52
NOMESCO Finland
2-person team, doctor-psychologist
+∞
6.3
6
*
RF220
NOMESCO Finland
NA
+∞
6.3
6
*
F22.0
ICD-10 Finland
Delusional disorder
+∞
6.3
6
*
F91.1
ICD-10 Finland
Unsocialized conduct disorder
+∞
6.3
6
*
F98.2
ICD-10 Finland
Feeding disorder of infancy and childhood
+∞
6.3
6
*
ICA04
NOMESCO Finland
Psychiatric treatment plan, psychotherapy supported by Social Insurance Institution
+∞
6.3
6
*
P16
ICPC
Acute alcohol abuse
27.3
6.3
8
*
RS210
NOMESCO Finland
NA
27.3
6.3
8
*
F42.9
ICD-10 Finland
Obsessive-compulsive disorder, unspecified
27.3
6.3
8
*
RS310
NOMESCO Finland
NA
27.3
6.3
8
*
G04BD04
ATC
oxybutynin; oral, transdermal
8.0
6.2
13
17
183
Kela drug reimbursment
Lamotrigin and topiramate
12.9
6.1
10
8
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
6.0
104
651

Mortality – FinRegistry

Association

Association between endpoint KRA_PSY_CHILDSOC_EXMORE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have KRA_PSY_CHILDSOC_EXMORE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: KRA_PSY_CHILDSOC_EXMORE – Social disorders starting during childhood or adolecense, excluding more controls

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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