Any mental disorder

KRA_PSY_ANYMENTAL

vascular dementia: A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F0[0-3]|F051|G30|F[1-9]
  • Hospital discharge: ICD-9 29[0-2]|2941A|29[5-9]|30|31[2-9]|3310A|3311A|4378A
  • Hospital discharge: ICD-8 29[0-1]|29440|29[5-9]|30[0-1]|3021|30[3-8]|310
  • Cause of death: ICD-10 F0[0-3]|F051|G30|F[1-9]
  • Cause of death: ICD-9 29[0-2]|2941A|29[5-9]|30|31[2-9]|3310A|3311A|4378A
  • Cause of death: ICD-8 29[0-1]|29440|29[5-9]|30[0-1]|3021|30[3-8]|310

2 out of 7 registries used, show all original rules.

142327

4. Check minimum number of events

None

142327

5. Include endpoints

143658

6. Filter based on genotype QC (FinnGen only)

143658

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1752582 883234 853645
Only index persons 1407999 748063 659936
Unadjusted period prevalence (%)
Whole population 24.51 25.30 23.85
Only index persons 26.42 27.50 25.19
Median age at first event (years)
Whole population 40.42 43.71 36.80
Only index persons 37.04 39.98 33.71

-FinnGen-

Key figures

All Female Male
Number of individuals 143658 83681 59977
Unadjusted period prevalence (%) 27.65 28.52 26.44
Median age at first event (years) 42.36 38.89 47.20

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
2688
5680
2.42
320.92
1.4
1.4
505.8
544.8
mg/l
1.21
2534
5454
16472
60796
1.46
319.72
1.9
1.7
1.1
1.2
mg/l
1.33
12301
46406
17135
63947
1.44
312.65
4.0
3.3
—
—
—
0
0
2430
4966
2.50
310.51
1.5
1.5
2493.5
2114.8
e6/l
0.09
1978
4035
2428
4961
2.50
310.36
1.4
1.5
30.9
33.9
e6/l
0.12
1885
3831
4428
11665
1.96
309.89
4.6
4.7
24.1
24.1
mmol/l
0.17
3950
10592
42263
160935
1.72
307.65
5.6
4.3
6.7
6.7
mmol/l
5.69
39629
148830
25944
96796
1.52
307.65
4.1
3.5
94.1
94.2
e6/l
0.01
18520
67298
32518
125764
1.52
307.65
3.1
2.8
118.7
121.3
ug/l
0.77
29927
117685
8024
23469
1.80
307.65
2.8
2.4
41.4
48.0
u/l
0.44
6807
20185
20262
64301
1.79
307.65
2.4
2.2
2.9
2.9
mg/l
0.07
17207
55353
28221
107288
1.51
307.65
8.9
8.4
1.2
1.2
inr
9.27
8347
31398
22181
83330
1.47
307.65
3.4
3.2
7.6
7.8
mmol/l
5.08
18619
70682
5112
8370
3.21
307.65
2.8
1.2
—
—
—
0
0
32909
112540
1.83
307.65
4.9
4.8
35.5
35.8
g/l
10.60
30448
104765
14539
27751
3.01
307.65
2.2
1.4
1.6
1.3
%
259.54
12676
24888
66218
300545
1.86
307.65
19.8
13.8
4.0
4.0
mmol/l
26.18
64610
292050
50354
212566
1.56
307.65
4.3
3.9
12.2
11.3
mm/h
29.19
46493
197799
5335
9490
2.95
307.65
2.8
1.2
—
—
—
0
0
4450
4382
5.34
307.65
3.6
1.3
—
—
—
0
0
16603
58696
1.53
307.65
4.4
3.6
1.0
1.0
kg/l
0.42
2298
9411
30970
127311
1.37
307.65
10.6
8.9
0.0
0.0
e9/l
0.85
25263
104957
23882
76168
1.84
307.65
2.4
2.0
247.5
194.9
u/l
6.25
22484
71452
3392
7766
2.24
307.65
2.4
2.3
619.6
505.7
ug/l
0.68
3153
7278
858
8
542.91
307.65
2.4
1.4
149.9
110.9
nmol/l
—
749
8
37616
145518
1.59
307.65
6.7
5.6
2.0
1.9
e9/l
1.15
33055
128999
2676
3846
3.58
307.65
3.0
2.6
33.8
34.3
umol/l
0.31
2262
3255
10864
32570
1.78
307.65
6.0
6.1
1.0
1.0
mmol/l
0.04
10078
30503
36762
140421
1.61
307.65
6.6
5.6
0.6
0.6
e9/l
9.48
31794
122188
17017
40568
2.42
307.65
1.9
1.7
1178.9
1156.6
nmol/l
2.00
12984
30724
26550
88004
1.79
307.65
3.6
3.0
35.1
33.1
u/l
1.84
24986
83836
21036
68489
1.75
307.65
4.6
4.1
—
—
—
0
0
6541
18416
1.85
307.65
3.9
3.4
4.7
4.6
kpa
0.73
6274
17887
34170
132805
1.53
307.65
6.8
5.8
2.8
2.9
%
18.15
31759
124296
5163
9465
2.86
307.65
2.7
1.2
—
—
—
0
0
53972
214327
1.92
307.65
8.0
7.2
78.9
77.5
u/l
8.14
50860
202148
64886
299996
1.60
307.65
17.7
12.0
22.8
23.4
mg/l
4.54
53609
232318
27830
107319
1.47
307.65
3.8
3.1
5.7
5.7
ph
0.04
14
88
9280
29956
1.63
307.65
2.8
2.8
8.5
8.5
umol/l
0.06
7742
26362
47312
198785
1.52
307.65
4.9
3.9
—
—
—
0
0
8133
24978
1.71
307.65
8.0
7.7
95.3
95.9
%
10.91
7850
24001
37982
145914
1.61
307.65
7.2
5.7
0.2
0.2
e9/l
2.08
33293
128858
1507
944
8.14
307.65
1.6
1.1
1.6
0.9
promille
23.70
1136
753
2524
3492
3.71
307.65
1.5
1.2
—
—
—
0
0
12279
41478
1.58
307.65
2.6
2.5
13.0
13.9
umol/l
1.18
11237
38675
924
882
5.30
307.65
1.0
1.0
332.4
335.0
ng/l
0.02
666
605
36926
141057
1.61
307.65
6.7
5.6
0.0
0.0
e9/l
2.54
31934
122708
1384
34
207.61
307.65
12.2
5.2
0.6
0.6
mmol/l
0.70
1275
27
25282
82701
1.80
307.65
2.9
2.4
56.0
59.2
u/l
10.71
23221
76550
9120
27900
1.72
307.65
7.6
7.3
11.9
12.8
kpa
43.10
8704
26616
46581
186196
1.66
307.65
5.2
3.9
1800.4
1083.8
e6/l
1.56
687
2453
11331
38163
1.57
307.65
2.5
2.5
2.4
2.3
g/l
0.36
10325
35553
35072
138288
1.51
307.65
6.9
5.8
28.0
28.4
%
7.81
32596
129484
16814
52502
1.78
307.65
1.7
1.6
24172315.2
40336755.7
pmol/l
2.92
13917
43886
34378
133530
1.53
307.65
7.1
6.0
8.5
8.6
%
4.36
32094
125652
9766
31416
1.64
307.65
1.9
1.7
—
—
—
0
0
9129
27917
1.73
307.65
7.6
7.3
1.1
0.9
mmol/l
4.63
7200
21912
34821
115254
1.95
307.65
6.5
5.9
1.2
1.2
mmol/l
5.86
31733
104400
31679
102805
1.94
307.65
2.1
1.8
95.4
96.6
pmol/l
4.22
17066
53689
7843
22566
1.83
307.65
4.4
4.1
1.9
1.8
mmol/l
2.94
6378
18475
54216
220916
1.82
307.65
4.5
3.7
14.6
14.8
pmol/l
34.85
49602
201760
7868
22613
1.83
307.65
4.4
4.1
5.9
5.8
kpa
9.54
7584
22045
1041
209
25.27
307.65
2.5
1.1
—
—
—
0
0
38557
139489
1.79
307.65
6.2
6.0
11.1
11.6
umol/l
8.62
36248
132469
2819
1080
13.54
307.65
5.7
2.7
370.0
357.5
umol/l
1.77
2471
892
5321
9341
2.99
307.65
2.8
1.2
—
—
—
0
0
37778
128356
1.95
307.65
7.1
6.6
1.2
1.2
mmol/l
5.61
31977
108193
26342
84824
1.85
307.65
3.0
3.5
2.4
2.4
mmol/l
3.71
22955
74586
7908
23063
1.80
307.65
2.4
2.3
0.2
0.2
g/l
1.27
7211
21704
16032
55815
1.56
307.65
2.8
2.5
6.2
5.3
e6/l
10.90
14088
48554
9722
31477
1.63
307.65
7.6
7.1
104.1
104.6
mmol/l
19.99
9500
30837
34603
136188
1.50
307.65
6.7
5.6
57.3
56.9
%
7.53
32243
128102
13379
40405
1.80
307.65
3.7
3.5
0.8
0.8
mmol/l
26.21
12419
37866
20237
72737
1.54
307.65
3.4
2.9
—
—
—
0
0
3647
1075
17.80
307.65
3.0
1.3
—
—
—
0
0
18921
68933
1.50
307.65
4.5
3.8
91.3
90.4
%
4.33
18343
67335
45078
196700
1.37
307.65
4.0
3.5
—
—
—
0
0
7009
20966
1.74
307.65
8.7
8.6
—
—
—
0
0
8051
23521
1.80
307.65
4.4
4.1
7.4
7.4
ph
0.19
35
128
33913
141540
1.36
307.65
4.1
3.3
0.0
0.0
estimate
1.40
6541
26231
22396
81666
1.53
307.65
3.6
3.1
74.2
97.1
e6/l
1.38
17317
61976
14244
44405
1.75
307.65
2.8
3.1
2.4
2.4
mmol/l
3.57
12320
38933
18943
55103
1.96
307.65
1.6
1.5
20.2
20.5
nmol/l
1.80
16570
47085
20695
74395
1.54
307.65
3.4
3.0
0.4
0.4
e6/l
0.74
15766
55220
4615
6175
3.92
307.65
2.8
1.2
—
—
—
0
0
8683
22197
2.08
307.65
2.1
2.3
372.9
374.5
nmol/l
0.25
7895
20656
22442
77679
1.64
307.65
3.4
2.8
—
—
—
0
0
41679
162910
1.63
307.65
10.7
8.3
4.2
4.0
e9/l
43.59
36473
142582
9126
27918
1.72
307.65
7.6
7.3
5.1
5.1
kpa
7.52
8718
26632
773
468
8.35
307.65
2.3
1.3
151.8
75.9
umol/l
6.32
409
222
33231
128608
1.53
307.65
6.8
5.9
0.7
0.7
%
5.97
30881
120459
14154
50099
1.51
307.65
4.1
3.4
271.8
599.3
ng/l
16.18
10329
37649
27210
99323
1.58
307.65
4.1
3.2
80.2
59.9
ng/l
0.48
18349
63313
19240
68719
1.54
307.65
7.7
6.6
—
—
—
0
0
418
108
19.48
307.65
2.0
2.6
16.0
18.5
umol/l
1.30
418
108
930
885
5.31
307.65
1.0
1.0
685.4
815.1
ng/l
8.90
650
579
17216
63556
1.46
307.65
1.3
1.3
1.6
1.8
u/ml
1.04
4408
17824
15237
51335
1.61
307.65
3.0
2.6
530.6
557.0
mosm/kgh2o
29.19
13009
43691
5313
9481
2.94
307.65
2.7
1.2
—
—
—
0
0
7494
21254
1.85
307.65
7.1
7.3
1.4
1.3
mmol/l
15.37
7162
20557
25926
94025
1.58
307.65
6.3
5.9
—
—
—
0
0
47471
196939
1.56
307.65
4.0
2.6
53.5
44.1
u/l
63.50
44298
185336
66151
299483
1.88
307.65
19.8
13.7
139.4
139.7
mmol/l
120.70
64658
291582
23090
74497
1.80
307.65
4.1
4.1
7.4
7.4
ph
1.31
4319
14435
61470
267902
1.81
307.65
5.5
4.3
2.0
2.1
mu/l
0.51
56929
246978
31168
110705
1.70
307.65
2.5
2.2
2992.9
77.4
nmol/l
0.50
28100
100520
5484
15597
1.82
305.07
5.1
4.7
—
—
—
0
0
2404
4957
2.48
301.58
1.3
1.3
3.8
3.7
mmol/l
5.40
2247
4676
18837
71924
1.42
301.33
3.1
2.9
1381.0
1369.8
ng/l
0.10
15758
61530
10466
35523
1.55
300.65
2.6
2.6
22.5
23.1
%
4.13
8847
30564
5491
15758
1.80
296.42
4.3
3.7
5.2
5.1
kpa
14.81
5092
14583
5436
15560
1.81
295.87
4.3
3.7
7.4
7.4
ph
1.61
680
2004
34098
143684
1.34
295.64
4.1
3.3
0.0
0.0
estimate
0.36
6530
26147
33773
142172
1.34
294.22
5.4
4.5
0.0
0.0
estimate
0.32
6699
26924
10895
37530
1.53
292.11
2.2
1.9
—
—
—
0
0
11506
40126
1.51
291.40
2.3
2.1
29.7
29.8
s
0.93
11132
38992
281
13
108.62
287.23
2.8
1.8
—
—
—
0
0
7378
23252
1.65
286.12
8.4
8.1
122.5
121.6
g/l
3.03
7140
22381
14984
55365
1.44
283.70
1.5
1.4
2.4
2.4
g/l
4.39
8674
35151
12721
45682
1.47
278.16
3.0
2.7
1.2
1.1
e6/l
0.59
7106
25992
4457
37696
0.57
270.00
1.3
1.3
—
—
—
0
0
9959
34320
1.52
263.86
1.7
1.6
—
—
—
0
0
11885
42632
1.47
259.13
3.2
2.8
3.2
2.7
e6/l
4.19
6317
23107
60772
282254
1.41
256.26
4.9
4.1
6.0
5.8
mmol/l
142.62
55553
260068
6984
22562
1.61
243.21
7.8
7.6
9.2
9.9
mmol/l
11.83
6622
21524
19045
75120
1.36
239.77
4.6
3.6
0.0
0.0
estimate
3.63
6424
25918
5058
15051
1.73
239.71
7.9
6.7
24.7
24.5
mmol/l
2.52
4780
13959
9163
31794
1.50
232.47
8.0
6.3
—
—
—
0
0
2168
4812
2.29
231.82
1.4
1.4
—
—
—
0
0
18829
116692
0.74
231.36
2.8
2.6
—
—
—
0
0
9942
35157
1.48
229.87
2.3
2.5
129.4
134.9
ug/g
0.60
7635
28069
9367
33006
1.48
219.49
21.6
24.3
1.3
1.4
inr
1.36
1201
5016
57386
265884
1.34
218.28
6.2
5.2
39.8
39.2
mmol/mol
36.47
53052
248006
15317
59096
1.37
217.48
2.0
1.8
—
—
—
0
0
3600
9938
1.85
217.39
1.7
1.6
350.3
274.6
mu/l
15.31
3230
9066
8275
28478
1.51
217.02
2.6
2.6
1.8
1.7
%
7.92
7173
25500
5114
15737
1.67
213.79
7.6
7.6
24.8
24.7
mmol/l
2.11
5062
15619
1699
3521
2.45
210.26
1.5
1.4
61.5
65.4
mmol/l
2.53
1301
2858
3870
11079
1.79
208.00
3.4
3.0
1.5
1.2
%
40.79
3855
11020
3381
9284
1.86
207.28
5.8
4.5
—
—
—
0
0
2701
6887
2.00
204.93
1.4
1.4
279.3
272.2
ug/g
0.71
1505
4048
21876
89746
1.31
203.47
2.6
2.3
—
—
—
0
0
6363
20950
1.57
202.57
2.5
2.2
6.9
7.5
ug/l
1.26
5365
18552
5331
16822
1.63
201.97
3.0
3.5
4.4
4.5
pmol/l
7.89
4625
15276
3015
8070
1.91
199.37
4.8
3.9
1.4
1.3
mmol/l
2.93
2967
7917
10145
37010
1.43
196.59
1.3
1.2
—
—
—
0
0
7317
25062
1.51
194.71
4.5
4.0
—
—
—
0
0
3892
11380
1.75
194.57
4.6
3.8
—
—
—
0
0
3755
10896
1.76
192.58
3.4
3.0
0.7
0.7
%
0.89
3610
10465
4943
15480
1.64
192.51
9.6
9.2
1.5
1.3
%
33.30
4910
15375
4936
15468
1.64
191.73
9.7
9.3
0.7
0.7
%
0.53
4900
15378
4751
14769
1.65
190.30
3.7
3.5
130.1
129.2
g/l
1.62
4631
14436
4942
15568
1.63
187.93
9.8
9.3
93.4
94.2
%
12.75
4914
15517
18887
76717
1.31
184.75
4.1
3.6
—
—
—
0
0
235
0
+∞
183.11
7.6
0.0
—
—
—
0
0
66685
318589
1.42
180.31
19.4
14.0
75.9
76.8
umol/l
7.11
66669
318402
10389
38629
1.40
179.32
1.4
1.3
471.5
569.8
titre
5.76
1947
7965
3453
9984
1.77
178.90
4.9
4.0
24.8
24.7
mmol/l
1.98
3211
9275
8753
31570
1.44
178.81
1.5
1.4
—
—
—
0
0
5705
18845
1.56
177.89
3.9
4.0
89.0
91.0
ng/l
0.69
4887
16449
2500
6544
1.94
175.95
1.3
1.3
—
—
—
0
0
259
101
12.88
173.08
1.2
1.1
—
—
—
0
0
2591
6956
1.90
169.37
5.0
4.2
3.8
3.9
mmol/l
3.19
2436
6553
6180
21028
1.51
168.15
3.8
3.3
—
—
—
0
0
4201
13055
1.65
167.76
9.5
9.6
24.3
24.3
mmol/l
0.04
3874
12277
2087
5229
2.03
165.55
1.4
1.3
—
—
—
0
0
16762
67921
1.30
162.88
2.5
2.2
—
—
—
0
0
6123
20956
1.50
161.75
4.1
3.7
1.2
1.2
mmol/l
1.74
5315
18396
1150
2257
2.58
158.45
1.6
1.7
—
—
—
0
0
66817
320422
1.40
157.76
11.9
9.2
27.5
26.4
u/l
14.90
64643
309741
215
71
15.20
154.01
1.4
1.0
1.6
—
mmol/l
—
5
0
1048
2015
2.63
150.16
1.5
1.4
280.1
279.8
mosm/kgh2o
0.12
791
1597
6413
22489
1.47
149.77
1.2
1.1
—
—
—
0
0
5919
20494
1.48
147.14
2.6
2.7
10.4
10.6
g/l
2.97
5381
18865
2069
5410
1.94
145.76
3.8
3.5
—
—
—
0
0
25741
111100
1.24
145.18
4.4
3.4
—
—
—
0
0
1969
5069
1.97
144.91
1.4
1.3
—
—
—
0
0
1969
5071
1.97
144.75
1.4
1.3
—
—
—
0
0
3746
11740
1.63
144.11
3.9
3.3
25.3
25.2
mmol/l
0.77
3622
11396
6044
21132
1.47
142.92
2.5
2.7
71.5
68.8
e9/l
5.54
4523
15931
2336
6430
1.85
141.25
4.5
3.6
7.4
7.4
ph
10.05
2001
5459
1340
2999
2.26
140.19
1.6
1.6
—
—
—
0
0
2759
22292
0.61
133.16
1.4
1.4
—
—
—
0
0
2051
5569
1.87
129.20
4.5
3.6
2.5
2.4
mmol/l
0.51
1419
3700
2051
5571
1.87
129.06
4.5
3.6
5.0
5.0
kpa
4.97
2001
5455
2059
5609
1.86
128.41
4.6
3.6
8.6
8.7
kpa
1.73
2008
5493
5488
19247
1.46
127.03
1.5
1.4
—
—
—
0
0
2579
7610
1.72
123.77
3.3
3.2
—
—
—
0
0
65680
315976
1.32
122.72
16.5
11.3
—
—
—
0
0
18662
78848
1.25
122.13
3.4
3.3
454.7
411.5
mg/l
0.54
12058
49984
19534
83029
1.24
120.81
4.1
4.0
11.2
9.0
mg/mmol
4.62
12456
52932
15763
65444
1.26
119.68
5.1
4.1
—
—
—
0
0
5782
20722
1.43
119.04
2.3
2.7
66.3
66.6
g/l
2.23
5181
19024
2565
7650
1.70
118.44
1.2
1.1
—
—
—
0
0
2168
6166
1.78
117.87
3.1
3.1
24.8
24.5
mmol/l
2.28
1919
5400
3058
9573
1.62
117.63
2.1
2.0
2.1
2.3
ug/l
0.28
2654
8505
2566
7677
1.70
117.14
1.2
1.2
—
—
—
0
0
12205
49251
1.29
116.23
1.3
1.3
35.9
35.6
iu/ml
0.03
3345
16018
53736
252934
1.22
115.70
21.3
14.4
13.7
13.6
%
47.09
52745
247558
30892
138010
1.20
115.23
4.2
3.9
—
—
—
0
0
4612
15924
1.48
115.01
1.8
1.9
1.3
1.3
g/l
0.09
4178
14614
2438
7293
1.70
111.29
1.2
1.3
83.4
129.9
titre
2.97
217
673
2750
8561
1.63
107.98
1.5
1.4
9.3
9.9
u/l
1.28
2185
7127
4048
13902
1.48
103.29
10.1
9.7
—
—
—
0
0
4632
16338
1.45
103.21
1.3
1.2
—
—
—
0
0
3353
11102
1.54
101.52
1.1
1.1
9.6
10.5
u/ml
0.04
52
171
2377
7238
1.67
101.52
1.2
1.2
859.1
1025.2
titre
0.46
56
221
2102
6195
1.72
101.09
4.5
3.7
8.4
8.4
kpa
0.19
1961
5775
1786
5079
1.78
97.01
3.4
3.9
—
—
—
0
0
973
2229
2.20
96.46
1.6
1.5
—
—
—
0
0
4703
16854
1.42
95.97
2.1
2.4
—
—
—
0
0
1088
2615
2.10
95.95
1.5
1.5
—
—
—
0
0
3548
12041
1.50
95.70
2.4
2.2
5711.9
6057.7
u/l
0.22
1181
5203
17113
73157
1.22
95.54
1.7
1.6
1.5
1.3
mmol/l
75.01
14609
61622
12089
49790
1.26
94.98
1.7
1.6
—
—
—
0
0
1438
3854
1.89
94.07
2.1
1.7
1.8
1.7
mmol/l
2.76
1410
3759
6189
23334
1.36
93.39
4.2
4.1
0.9
0.9
%
0.10
1776
6360
1829
5310
1.74
92.64
2.7
2.4
16.5
16.5
%
0.07
929
2762
1496
4088
1.85
92.27
1.4
1.3
25.1
26.9
u/l
1.17
1184
3458
11349
46573
1.26
91.57
1.3
1.3
10.4
12.0
u/ml
1.16
4063
18871
5981
22535
1.36
90.48
1.5
1.4
—
—
—
0
0
3190
10814
1.50
86.31
1.3
1.2
0.5
0.9
u/ml
1.76
278
923
5163
19138
1.38
86.29
2.3
2.4
23.4
23.4
au/ml
0.01
214
1299
2494
8008
1.58
86.10
6.0
5.6
1.4
1.3
mmol/l
4.28
2202
7085
5633
21251
1.35
84.22
3.9
3.9
0.7
0.7
%
0.12
1270
4636
5646
21327
1.35
83.70
3.1
2.8
189.9
201.7
ng/l
1.02
5112
19416
4752
17472
1.39
83.29
1.3
1.3
46.0
50.2
au/ml
0.44
146
775
652
1343
2.44
81.75
1.3
1.3
32.9
35.1
mmol/l
1.33
552
1173
427
696
3.08
81.54
3.0
2.8
29.7
27.9
umol/l
1.77
317
546
5845
22292
1.34
81.23
4.3
4.1
0.1
0.1
%
0.71
1613
5956
3338
11652
1.45
77.92
1.7
1.8
1.5
1.5
g/l
1.51
2846
9969
1555
4542
1.73
77.09
2.9
2.8
—
—
—
0
0
1164
3121
1.88
76.07
2.0
1.7
89.4
90.1
%
3.36
1145
3075
1182
3193
1.87
75.53
1.9
1.7
3332.4
3195.0
titre
0.04
55
127
3030
10454
1.47
75.02
5.4
4.8
1.9
1.6
%
16.18
2836
9799
1498
4367
1.73
74.77
1.1
1.1
—
—
—
0
0
5241
19904
1.34
74.63
1.2
1.2
124.0
150.5
iu/ml
3.98
1785
7841
2827
9635
1.49
74.36
1.7
1.7
—
—
—
0
0
5505
21075
1.33
74.25
4.4
4.1
0.0
0.3
%
5.00
1377
5048
857
2076
2.08
74.17
2.1
2.2
19.5
18.5
nmol/l
2.09
793
2001
479
903
2.67
71.45
2.6
2.2
56.2
51.7
umol/l
2.05
400
752
510
996
2.57
71.17
3.2
2.7
—
—
—
0
0
2955
10297
1.45
69.47
5.5
4.9
0.9
0.9
%
0.68
2769
9646
5641
21879
1.31
69.25
2.4
2.1
12.3
12.5
nmol/l
1.15
4890
19694
1148
3170
1.83
68.57
1.5
1.6
—
—
—
0
0
1461
4348
1.70
67.78
1.1
1.1
—
—
—
0
0
3887
14309
1.38
67.19
1.4
1.3
25.3
27.9
iu/l
4.55
3223
12537
2658
9131
1.47
67.15
3.3
3.3
0.3
0.3
g/l
0.86
1191
4179
187
195
4.81
63.26
2.1
1.1
—
—
—
0
0
1016
2814
1.82
60.16
16.0
5.3
7.6
7.2
mmol/l
1.65
826
2302
1800
5846
1.55
59.04
2.0
1.8
189.2
198.9
pmol/l
3.07
1687
5593
1129
3262
1.74
58.17
7.0
6.1
11.6
11.4
mg/l
0.56
1019
3009
2407
8349
1.46
57.83
1.8
1.7
0.2
0.2
g/l
0.95
2282
7930
743
1883
1.99
57.18
1.3
1.2
2.1
2.1
mmol/l
0.05
681
1757
2460
8604
1.45
56.60
1.8
1.7
1.2
1.2
g/l
3.57
2334
8202
83
6
69.34
56.35
1.3
1.0
510.5
785.4
nmol/l
—
83
6
4776
18611
1.30
56.20
1.3
1.3
272.7
234.1
u/ml
0.75
4376
17306
16950
75310
1.16
55.19
2.6
2.6
3206.8
4450.6
umol/l
4.24
14453
66335
1816
6009
1.53
54.81
2.2
2.1
130.7
130.7
g/l
0.00
1331
4368
1871
6255
1.51
53.85
1.2
1.3
—
—
—
0
0
3203
11842
1.37
53.68
1.5
1.5
14.1
14.6
u/ml
0.06
82
348
4754
18688
1.29
52.26
1.2
1.2
—
—
—
0
0
633
1575
2.02
51.26
1.2
1.3
—
—
—
0
0
780
2096
1.87
50.79
1.1
1.2
37.4
46.1
mg/l
4.14
663
1747
6065
24661
1.25
50.52
4.5
3.6
—
—
—
0
0
1702
5654
1.52
50.46
7.1
6.5
11.4
11.2
mmol/l
2.03
1537
5084
1702
5655
1.52
50.42
7.1
6.5
104.8
105.3
mmol/l
3.21
1537
5086
1186
3622
1.65
50.05
1.3
1.3
0.2
0.3
nmol/l
1.54
91
211
540
1278
2.12
49.75
1.4
1.2
269.2
336.5
u/l
0.73
501
1191
720
1900
1.91
49.50
1.1
1.1
285.8
291.5
mg/l
1.04
644
1718
462
1026
2.26
49.49
2.0
1.9
1.9
2.0
umol/l
0.55
436
966
2418
8648
1.41
49.24
1.9
1.7
40.5
41.1
nmol/l
0.63
2337
8473
1185
3639
1.64
48.97
1.3
1.3
1.0
1.3
nmol/l
0.25
1130
3514
2873
10604
1.37
48.60
2.4
2.2
21.4
21.5
s
0.12
2511
9196
2632
9590
1.39
48.14
2.1
2.3
7.3
7.4
g/l
0.38
1935
7191
2567
9316
1.39
48.06
1.6
1.6
233.3
292.5
titre
0.57
103
393
1358
4340
1.58
47.77
3.5
3.6
63.2
65.6
%
3.09
1350
4323
746
2020
1.86
47.51
1.1
1.1
243.7
278.1
mg/l
3.20
654
1781
676
6033
0.56
47.19
1.5
1.6
—
—
—
0
0
2619
9570
1.38
47.08
2.1
2.3
3.8
3.8
g/l
0.18
1863
6823
2483
8997
1.39
46.91
2.1
2.3
3.0
3.1
g/l
0.77
1888
7036
2089
7343
1.44
46.77
2.0
2.2
37.9
37.7
g/l
0.38
1764
6361
3642
14026
1.32
46.44
2.4
2.4
—
—
—
0
0
1079
3291
1.65
45.80
1.3
1.3
—
—
—
0
0
2456
8944
1.39
45.04
2.0
2.3
10.1
10.3
g/l
1.84
2021
7528
503
1209
2.09
44.65
1.3
1.3
62.2
66.1
%
0.34
51
151
386
832
2.33
44.26
1.4
1.5
512.8
766.7
mu/l
0.99
364
799
56
14
20.04
44.23
1.7
1.0
273.0
170.7
nmol/l
—
43
7
3624
14068
1.30
43.58
1.1
1.1
179.6
208.5
titre
0.27
79
410
2632
9749
1.36
43.51
1.3
1.3
—
—
—
0
0
2805
10499
1.35
43.38
1.6
1.7
—
—
—
0
0
390
853
2.30
43.32
1.4
1.5
73.1
72.7
%
0.19
368
820
242
417
2.91
42.54
1.5
1.3
—
—
—
0
0
52
12
21.71
42.04
1.7
1.3
328.6
213.7
nmol/l
—
38
6
508
1257
2.03
41.87
2.3
2.2
25.2
56.7
umol/l
3.20
59
126
427
990
2.17
41.48
2.0
1.9
28.2
29.2
umol/l
0.99
416
953
59
21
14.08
41.17
1.2
1.0
—
—
mmol/l
—
0
0
1244
4039
1.55
40.94
2.2
2.0
8.7
5.5
titre
0.33
31
107
560
1453
1.94
40.54
1.3
1.3
4.9
5.1
umol/l
0.34
501
1355
7535
32013
1.20
40.41
1.3
1.4
—
—
—
0
0
625
1697
1.85
39.57
3.3
3.2
30.4
25.0
mu/l
1.85
582
1603
2089
7573
1.39
39.35
1.2
1.1
—
—
—
0
0
1606
5551
1.46
39.30
1.3
1.3
280.6
253.4
u/ml
2.98
1048
3506
4896
19980
1.24
39.08
3.4
2.4
4.2
4.1
e9/l
0.79
3660
15859
17633
80134
1.13
38.80
3.7
3.0
—
—
—
0
0
1127
3635
1.56
38.20
1.1
1.1
1.5
1.5
g/l
1.77
1005
3316
759
2223
1.72
37.49
1.4
1.3
1.4
1.4
nmol/l
0.31
691
2004
7825
33580
1.19
37.31
4.4
4.3
31.3
32.5
%
14.97
5448
23451
1329
4480
1.49
36.86
1.5
1.6
0.7
0.8
g/l
0.92
1013
3368
157
225
3.50
36.59
3.1
3.4
39.1
41.1
umol/l
0.44
138
184
1539
5355
1.45
36.41
2.3
1.9
0.9
0.8
nmol/l
2.73
1253
4545
2065
7586
1.37
35.93
1.5
1.5
20.6
13.2
iu/ml
0.73
35
195
653
1862
1.76
35.40
1.1
1.1
—
—
—
0
0
523
1398
1.88
34.81
1.1
1.1
2.5
6.4
nmol/l
1.45
94
285
490
1285
1.92
34.50
3.0
2.3
7.4
7.4
ph
0.18
157
476
357
834
2.15
34.17
1.4
1.4
14.2
15.3
pmol/l
2.25
286
720
1313
4485
1.47
34.16
1.5
1.4
0.4
0.4
nmol/l
1.02
1003
3529
607
1718
1.78
33.77
1.1
1.1
—
—
—
0
0
2321
8772
1.34
33.65
10.9
8.7
—
—
—
0
0
473
1242
1.91
33.21
1.7
1.4
20.1
27.7
umol/l
6.42
447
1183
3601
14458
1.26
33.04
3.0
2.6
0.3
0.3
e6/l
0.38
3508
14043
1600
5717
1.41
32.80
1.2
1.2
41.7
43.7
u/ml
0.15
137
579
7772
33676
1.17
32.74
1.7
1.7
—
—
—
0
0
9356
53083
0.87
32.53
2.8
2.9
0.7
0.8
ug/l
10.89
6362
33577
3094
12224
1.28
32.40
1.1
1.1
—
—
—
0
0
2052
7659
1.35
32.32
4.8
3.8
1.5
1.5
mg/l
1.85
1895
7091
532
1468
1.82
32.16
1.5
1.4
6.0
5.9
u/l
0.12
457
1236
413
1048
1.98
31.97
2.3
1.9
—
—
—
0
0
1090
3633
1.51
31.96
1.4
1.6
59.8
63.0
mu/l
0.19
952
3283
41
11
18.67
31.69
1.3
1.1
—
—
—
0
0
3011
11893
1.28
31.59
1.9
2.0
39.5
39.3
u/l
0.20
2674
10637
2047
7665
1.35
31.57
2.8
3.4
5.5
4.1
ratio
0.19
181
592
2068
7757
1.34
31.54
1.3
1.3
34.4
37.0
u/ml
0.15
102
492
2098
7913
1.34
30.85
2.9
3.4
49.7
72.1
mg/l
1.47
1674
6443
2264
8638
1.32
30.76
3.2
2.6
3.5
3.6
g/l
1.19
2149
8259
2093
7904
1.34
30.52
2.9
3.4
36.9
43.8
mg/l
1.36
1660
6451
315
733
2.16
30.51
1.2
1.3
22.9
20.2
%
0.21
43
135
1619
5873
1.39
30.44
1.6
1.6
—
—
—
0
0
537
1513
1.78
30.39
3.8
4.0
—
—
—
0
0
99
114
4.35
30.38
1.3
1.4
92.9
74.1
umol/l
3.45
88
106
747
2313
1.62
30.10
1.2
1.3
—
—
titre
—
0
0
1012
3364
1.51
30.08
1.3
1.4
335.5
288.1
pmol/l
0.81
768
2614
1634
5957
1.38
29.83
1.5
1.4
18.4
21.2
u/ml
0.35
26
115
2367
9134
1.31
29.66
2.9
2.4
91.8
92.0
%
0.19
2204
8518
875
2832
1.55
29.35
1.4
1.4
—
—
—
0
0
1644
6017
1.38
29.31
1.5
1.5
—
—
—
0
0
871
2832
1.55
28.65
1.4
1.4
2.8
3.0
g/l
1.83
626
1946
870
2831
1.54
28.52
1.4
1.4
0.4
0.4
g/l
2.34
628
1948
685
2107
1.63
28.37
1.2
1.1
357.2
373.0
nmol/l
1.08
570
1812
870
2835
1.54
28.34
1.4
1.4
6.6
6.9
g/l
1.04
624
1946
432
1169
1.86
27.84
1.6
1.6
4.2
5.7
nmol/l
0.29
359
976
2601
10251
1.28
27.77
1.1
1.1
—
—
—
0
0
1847
6952
1.34
27.56
1.8
1.9
13.7
20.5
iu/l
0.27
640
2638
392
1034
1.90
27.28
2.3
2.1
—
—
—
0
0
394
1042
1.90
27.21
2.3
2.5
9.3
9.0
mmol/l
0.69
294
739
946
3175
1.50
26.93
2.2
2.0
25.2
27.3
mg/l
0.50
279
819
277
648
2.14
26.58
1.3
1.4
—
—
—
0
0
257
583
2.21
26.54
1.4
1.2
130.5
126.3
nmol/l
0.11
177
445
34
0
+∞
26.48
2.9
0.0
2.3
—
ug/l
—
25
0
1457
5325
1.38
26.25
1.2
1.2
100.0
146.3
titre
0.77
32
111
880
2927
1.51
26.16
1.6
1.5
—
—
—
0
0
880
2928
1.51
26.12
1.6
1.5
—
—
—
0
0
880
2928
1.51
26.12
1.6
1.5
—
—
—
0
0
880
2929
1.51
26.08
1.6
1.5
—
—
—
0
0
257
590
2.18
25.82
1.3
1.3
17.0
16.9
umol/l
0.18
229
528
1498
5529
1.36
25.41
1.5
1.5
114.0
111.4
u/ml
0.26
307
1265
4388
18483
1.20
25.37
3.2
2.7
—
—
—
0
0
1709
6475
1.33
24.43
1.6
1.6
16284.0
12710.4
e6/l
1.69
1211
4756
1700
6437
1.33
24.41
2.3
2.4
131.8
105.0
ug/min
1.15
980
3918
998
3457
1.45
24.34
2.6
2.5
—
—
—
0
0
1352
4952
1.37
24.08
3.4
3.1
—
—
—
0
0
607
1891
1.61
24.01
1.4
1.4
12.0
12.1
umol/l
0.20
561
1826
469
1366
1.72
23.87
1.5
1.6
1.2
1.2
nmol/l
0.22
357
1098
917
3137
1.47
23.85
2.6
2.5
—
—
—
0
0
1579
5948
1.34
23.50
3.0
3.5
—
—
—
0
0
6115
34983
0.86
23.21
1.5
1.4
—
—
—
0
0
1217
4424
1.38
22.72
1.1
1.1
8788.1
540.1
iu/ml
0.54
285
1007
341
916
1.87
22.60
2.3
2.6
1.1
1.2
ug/l
0.22
318
870
1868
7249
1.30
22.52
1.3
1.3
8.9
8.8
u/ml
0.01
269
1184
1053
3754
1.41
22.03
2.6
2.9
1068.7
659.8
u/ml
0.18
1006
3574
2945
17816
0.82
21.70
1.7
1.6
—
—
—
0
0
615
1977
1.56
21.42
2.8
2.5
764.4
699.7
e6/l
0.46
227
821
1836
7159
1.29
21.37
1.3
1.3
5.0
6.5
u/ml
0.42
168
794
329
892
1.85
21.24
2.1
2.2
66.6
62.4
ug/l
0.31
321
869
1138
4140
1.38
21.18
1.4
1.4
—
—
—
0
0
188
412
2.29
21.13
2.5
2.4
1.2
1.2
mmol/l
0.57
179
393
805
2752
1.47
21.08
3.6
3.4
—
—
—
0
0
236
572
2.07
20.87
1.1
1.1
—
—
—
0
0
112
189
2.97
20.69
2.2
2.1
1.2
1.3
umol/l
0.54
102
168
1383
5210
1.34
20.63
1.5
1.7
—
—
—
0
0
102
164
3.12
20.35
1.9
1.7
43.2
47.8
umol/l
0.77
102
164
1163
4297
1.36
19.72
1.4
1.5
—
—
—
0
0
3049
12710
1.21
19.65
1.9
1.8
—
—
—
0
0
1511
5808
1.31
19.60
1.2
1.2
3.0
14.8
u/ml
2.01
12
90
224
546
2.06
19.56
1.1
1.1
6.2
7.2
mg/g
1.18
210
521
198
462
2.15
19.30
1.7
1.8
—
—
—
0
0
628
2090
1.51
18.80
1.2
1.2
—
—
—
0
0
683
4925
0.69
18.73
3.8
2.3
13.2
13.1
%
0.77
675
4860
820
2886
1.43
18.52
3.3
3.7
—
—
—
0
0
353
1023
1.73
18.43
2.8
2.8
—
—
—
0
0
1822
7239
1.27
18.32
1.4
1.4
—
—
—
0
0
809
2847
1.43
18.29
1.2
1.2
60.7
66.6
u/l
0.88
545
1922
1179
4420
1.34
18.23
1.3
1.2
3.7
3.8
u/ml
0.19
519
2010
1510
5863
1.30
18.22
1.2
1.2
6.3
5.8
u/ml
0.07
97
475
632
2131
1.49
17.81
1.1
1.2
—
—
—
0
0
590
1964
1.51
17.68
2.8
2.5
527.0
528.6
e6/l
0.02
489
1623
779
2744
1.43
17.55
2.7
2.3
1.2
1.1
e9/l
1.97
466
1640
171
1699
0.50
17.47
1.3
1.3
—
—
—
0
0
167
380
2.20
17.34
2.5
2.2
1.2
1.2
mmol/l
0.06
160
361
68909
341241
1.13
17.34
26.6
17.4
255.8
251.7
e9/l
47.41
67355
332333
469
1493
1.58
17.16
1.3
1.3
390.8
425.6
titre
0.06
39
93
1899
7650
1.25
17.00
2.0
2.1
11.0
10.8
mg/l
0.46
1756
7170
2419
10006
1.22
16.90
2.4
2.7
—
—
—
0
0
28
5
28.04
16.81
1.4
1.2
171.7
177.5
nmol/l
—
18
5
821
5632
0.73
16.76
1.2
1.2
—
—
—
0
0
455
1454
1.57
16.41
1.3
1.3
67.7
73.1
titre
0.13
39
123
1149
4361
1.32
16.40
3.0
3.4
1.5
1.4
%
0.21
899
3380
704
2468
1.43
16.32
2.6
2.1
43.9
39.8
%
1.50
90
312
687
2412
1.43
15.82
1.2
1.2
—
—
—
0
0
2003
12190
0.82
15.72
1.5
1.4
—
—
—
0
0
114
228
2.51
15.67
1.1
1.2
—
—
—
0
0
564
1910
1.48
15.64
2.8
2.5
0.2
0.2
e9/l
0.03
483
1626
33
24
6.89
15.56
1.1
1.2
—
—
—
0
0
6496
29214
1.12
15.44
1.5
1.4
—
—
—
0
0
892
3290
1.36
15.42
2.0
2.3
32.6
32.7
pg
0.07
881
3269
392
1232
1.60
15.20
36.8
35.2
7.4
7.3
ug/l
0.37
356
1118
650
2277
1.43
15.17
1.2
1.2
135.8
196.9
titre
1.39
101
399
629
2190
1.44
15.17
1.8
2.0
1.0
1.0
g/24h
0.08
40
130
647
2272
1.43
14.92
1.2
1.2
138.6
194.9
titre
0.37
22
76
1155
4452
1.30
14.81
3.2
3.1
0.8
0.8
nmol/l
0.35
845
3457
68914
341579
1.12
14.81
26.4
17.3
30.3
30.2
pg
24.38
67965
337101
1152
4440
1.30
14.79
1.2
1.2
—
—
—
0
0
49
58
4.23
14.78
2.6
3.1
—
—
—
0
0
7549
34324
1.11
14.74
1.7
1.8
—
—
—
0
0
468
1545
1.52
14.69
2.8
2.7
40.0
39.4
%
0.21
151
539
68918
341625
1.12
14.61
26.4
17.3
91.0
90.6
fl
72.76
67968
337129
68921
341663
1.12
14.44
26.5
17.4
4.5
4.5
e12/l
202.67
67153
331843
2045
8456
1.22
14.39
1.1
1.1
6.6
5.5
u/ml
0.29
214
1211
6176
27806
1.12
14.37
3.5
4.2
23.5
25.3
ug/l
0.18
5001
22110
624
2193
1.43
14.35
1.1
1.1
58.7
64.7
u/ml
—
6
28
68934
341745
1.12
14.33
26.6
17.4
7.0
6.6
e9/l
179.25
67192
331912
250
707
1.77
14.32
2.4
1.7
—
—
—
0
0
758
2760
1.38
14.23
2.8
2.8
—
—
—
0
0
137
314
2.19
14.10
1.4
1.4
48.3
54.7
%
0.63
56
163
268
2207
0.61
14.09
1.2
1.3
1.4
1.5
g/l
0.25
32
107
356
1115
1.60
14.05
2.6
2.2
11.2
11.1
%
0.02
337
1034
516
1757
1.47
14.00
1.5
1.5
26.1
23.7
u/ml
0.39
111
322
1107
4277
1.30
13.99
1.1
1.1
117.9
117.9
%
0.01
997
3874
94
181
2.60
13.96
1.3
1.2
16.8
14.8
nmol/l
0.45
30
46
669
2395
1.40
13.90
3.0
3.0
52.2
54.8
mg/l
0.07
485
1714
2398
10106
1.19
13.83
1.3
1.3
225.8
224.6
miu/ml
0.05
934
5022
825
3060
1.35
13.82
1.5
1.6
27.3
34.8
iu/ml
0.97
42
140
1273
5018
1.27
13.78
1.5
1.5
—
—
—
0
0
934
3532
1.33
13.77
1.2
1.2
59.0
51.2
u/ml
0.34
52
236
68928
341808
1.12
13.62
26.7
17.5
134.5
136.3
g/l
186.23
67977
337364
60932
300542
1.08
13.28
5.0
4.5
2.7
2.8
mmol/l
47.72
55953
279957
618
2204
1.41
13.15
2.4
2.0
73.4
72.0
%
1.38
588
2125
1416
5691
1.25
13.05
3.6
3.0
1.6
1.6
mmol/l
1.70
1388
5570
128
295
2.17
13.04
2.6
2.4
1.0
1.5
mmol/l
1.65
89
211
1540
6252
1.24
12.97
2.2
2.1
—
—
—
0
0
175
457
1.92
12.88
1.3
1.3
—
—
—
0
0
397
1306
1.52
12.75
1.1
1.1
6.5
10.7
u/ml
1.51
77
221
343
1092
1.58
12.71
2.5
2.1
27.5
29.1
%
1.27
326
1035
277
838
1.66
12.59
2.3
1.8
482.6
3446.7
e6/l
1.75
195
567
289
886
1.64
12.49
5.4
6.7
25.0
25.0
mmol/l
0.00
266
797
2892
12493
1.17
12.45
1.2
1.2
—
—
—
0
0
115
259
2.22
12.39
1.4
1.2
—
—
—
0
0
204
568
1.80
12.38
1.7
1.3
11.1
14.4
g/l
4.65
143
447
837
3167
1.33
12.35
1.8
2.0
25.8
24.5
ug/l
0.17
816
3103
305
955
1.60
12.14
4.5
5.1
—
—
—
0
0
222
643
1.73
11.84
2.2
2.1
—
—
—
0
0
509
1790
1.43
11.78
1.5
1.4
11.9
12.9
u/l
3.17
494
1730
355
1161
1.53
11.75
4.8
5.4
1023.8
3311.2
mg/l
1.63
260
832
680
2514
1.36
11.73
1.3
1.4
77647.6
116269.5
e6/l
1.04
451
1735
601
2178
1.38
11.72
2.4
2.0
12.9
14.2
%
1.58
320
1012
512
1807
1.42
11.62
1.1
1.1
—
—
—
0
0
263
805
1.64
11.49
1.1
1.1
—
—
—
0
0
187
520
1.80
11.44
1.3
1.2
—
—
—
0
0
205
587
1.75
11.39
1.2
1.2
313.1
286.2
pmol/l
0.28
139
447
90
189
2.39
11.35
4.3
3.6
2.1
2.2
mg/l
0.16
79
160
268
827
1.62
11.35
2.7
2.0
430.6
925.8
e6/l
0.62
162
418
281
879
1.60
11.27
1.2
1.2
—
—
—
0
0
437
1510
1.45
11.13
1.4
1.6
6.6
8.4
ug/l
2.21
393
1365
181
503
1.80
11.11
1.4
1.3
30.4
38.9
g/l
0.26
130
405
311
1003
1.55
10.99
2.5
2.3
—
—
—
0
0
198
569
1.74
10.90
1.5
1.6
0.4
0.4
ug/l
0.23
128
382
156
416
1.88
10.89
1.5
1.3
763.5
112.1
ng/l
0.47
79
290
242
737
1.65
10.81
2.2
1.7
4642.6
11943.6
e6/l
1.45
138
388
552
2001
1.38
10.80
2.9
2.2
—
—
—
0
0
3120
13700
1.15
10.79
3.9
3.2
—
—
—
0
0
178
498
1.79
10.72
1.1
1.1
0.6
3.6
umol/24h
0.53
81
256
807
3103
1.31
10.70
2.8
2.2
—
—
—
0
0
13676
72427
0.93
10.65
3.9
4.1
21.5
22.1
%
3.97
6000
34270
703
2654
1.33
10.62
2.9
3.4
58.2
58.3
%
0.07
444
1711
791
3037
1.31
10.61
2.3
2.3
—
—
—
0
0
170
471
1.81
10.57
1.6
1.6
—
—
—
0
0
706
4609
0.76
10.40
1.2
1.2
—
—
—
0
0
385
1317
1.47
10.37
1.2
1.1
3.6
3.9
iu/ml
0.22
26
108
159
434
1.84
10.37
1.4
1.6
5.3
6.6
nmol/l
0.74
150
417
445
1570
1.42
10.20
1.2
1.2
—
—
—
0
0
182
522
1.75
10.13
1.3
1.3
105.8
66.4
mu/l
0.45
133
399
664
2505
1.33
10.11
1.7
1.5
—
—
—
0
0
111
273
2.04
9.76
4.3
5.8
56.7
263.9
g/mol
0.62
100
252
868
3422
1.27
9.56
1.3
1.3
—
—
—
0
0
136
364
1.87
9.46
1.2
1.2
—
—
—
0
0
1055
4262
1.24
9.44
2.1
2.2
7.7
6.8
umol/l
0.55
758
3140
560
2088
1.35
9.27
1.1
1.1
—
—
—
0
0
253
813
1.56
9.18
1.6
1.5
—
—
—
0
0
677
2601
1.31
9.12
1.2
1.1
—
—
—
0
0
1305
5411
1.21
9.12
3.8
3.1
7.7
7.5
mmol/l
1.39
1282
5310
403
1430
1.41
9.02
1.5
1.5
—
—
—
0
0
314
1066
1.48
8.87
1.1
1.1
589.1
453.9
ng/l
0.16
55
259
390
1382
1.42
8.81
1.7
1.8
—
—
—
0
0
136
374
1.82
8.75
1.0
1.0
76.9
82.4
ug/l
0.79
114
301
59
115
2.57
8.74
1.1
1.2
16.2
16.7
umol/l
0.32
48
99
57542
284218
1.06
8.72
19.2
12.6
39.6
40.1
%
35.89
40046
216753
421
1518
1.39
8.62
2.0
1.7
2.3
2.6
u/field
0.37
301
1087
142
402
1.77
8.35
3.8
2.8
14.9
14.8
ml/dl
0.07
126
378
74
165
2.25
8.32
1.2
1.2
31.2
21.7
%
0.40
13
53
754
2977
1.27
8.29
1.4
1.5
6580.3
2092.0
e6/l
2.04
573
2127
1027
4201
1.23
8.26
1.3
1.3
30.5
35.7
u/l
0.72
892
3670
69
150
2.30
8.21
2.0
1.8
219.7
162.1
ug/g
1.24
55
133
31
42
3.70
8.09
1.3
1.0
75.8
60.2
mu/l
0.14
20
32
70
155
2.26
8.01
1.6
2.4
12.0
7.8
nmol/l
0.25
64
148
332
1164
1.43
8.00
6.4
11.1
—
—
—
0
0
439
2941
0.75
7.95
1.6
1.6
7.9
7.5
mmol/l
2.55
264
1717
527
1996
1.32
7.94
1.7
1.4
63.5
72.2
umol/l
2.21
30
176
556
2122
1.31
7.94
1.9
1.7
7.0
6.6
mmol/l
2.11
418
1545
118
321
1.84
7.90
2.8
2.3
0.6
0.6
u/field
0.18
118
321
153
451
1.70
7.87
2.1
2.2
2.4
2.7
mmol/l
1.30
139
404
353
1257
1.41
7.82
29.5
28.1
119.3
117.3
ug/l
0.20
282
1069
143
415
1.73
7.77
1.1
1.1
2.7
8.3
pmol/l
0.73
17
52
59856
296223
1.06
7.74
4.5
4.1
4.6
4.7
mmol/l
80.06
55213
277645
149
441
1.69
7.57
1.1
1.1
—
—
—
0
0
827
3340
1.24
7.54
1.4
1.5
32.7
33.2
g/l
0.52
743
3014
532
2039
1.31
7.41
1.5
1.3
—
—
—
0
0
57423
283986
1.05
7.27
4.0
3.7
1.4
1.3
mmol/l
197.36
52299
263977
680
2698
1.26
7.25
1.8
2.1
—
—
—
0
0
194
623
1.56
7.19
1.6
1.7
1.0
0.3
mmol/l
1.40
184
589
977
4041
1.21
7.12
1.2
1.2
—
—
—
0
0
376
1377
1.37
7.11
1.1
1.2
19.9
12.6
u/ml
0.33
42
129
1308
7680
0.85
7.11
1.4
1.5
—
—
—
0
0
449
1691
1.33
7.09
2.9
2.5
0.2
0.4
e9/l
1.06
432
1654
1636
9440
0.86
7.07
1.4
1.4
—
—
—
0
0
65
148
2.20
7.04
1.5
1.5
13.0
13.1
%
0.01
44
109
1307
7659
0.85
6.94
1.4
1.5
—
—
—
0
0
71
169
2.10
6.92
1.5
1.5
37.2
37.3
%
0.00
45
116
40
72
2.78
6.91
1.2
1.0
303.0
173.4
pmol/l
1.08
22
43
990
4116
1.21
6.86
1.8
1.7
—
—
—
0
0
113
950
0.59
6.78
3.3
3.1
—
—
—
0
0
1343
7835
0.86
6.75
1.5
1.5
—
—
—
0
0
113
949
0.60
6.75
6.7
6.3
—
—
—
0
0
362
1330
1.36
6.74
1.6
1.6
5.3
5.8
mmol/24h
0.30
28
103
559
2186
1.28
6.74
2.1
1.9
2.0
2.3
u/field
0.72
257
945
678
2717
1.25
6.69
1.4
1.5
65800.8
53035.6
e6/l
0.47
438
1595
82
210
1.96
6.63
1.2
1.2
—
—
—
0
0
207
689
1.51
6.58
2.1
1.9
—
—
—
0
0
470
1804
1.31
6.54
2.9
3.4
124.2
134.2
nmol/l
0.23
460
1783
126
372
1.70
6.53
1.7
1.6
—
—
—
0
0
93
251
1.86
6.47
1.3
1.1
—
—
—
0
0
56
125
2.24
6.38
1.4
1.3
0.9
1.8
%
0.86
35
85
616
2456
1.26
6.37
2.3
2.5
0.5
0.6
g
—
5
19
61
142
2.15
6.32
1.2
1.0
—
—
—
0
0
340
1256
1.36
6.17
2.2
2.2
21.5
241.8
ug/l
1.82
324
1198
115
338
1.70
6.09
1.6
1.3
—
—
—
0
0
791
3260
1.22
6.06
1.2
1.2
—
—
—
0
0
840
3483
1.21
6.05
2.4
2.5
—
—
—
0
0
543
2149
1.27
6.01
2.3
2.3
683.4
674.1
ml
0.18
376
1484
330
1222
1.35
5.92
1.3
1.2
—
—
—
0
0
650
2632
1.24
5.91
1.5
1.6
27.4
32.5
%
3.13
401
1658
194
656
1.48
5.78
1.2
1.2
—
—
—
0
0
104
302
1.73
5.77
1.0
1.0
0.1
0.2
u/ml
0.32
62
181
317
1172
1.36
5.76
1.7
1.7
—
—
—
0
0
151
484
1.56
5.74
2.3
2.5
7.1
7.5
mmol/l
0.68
89
291
365
1380
1.33
5.72
1.6
1.6
—
—
—
0
0
479
1881
1.28
5.68
1.0
1.0
—
—
—
0
0
278
1009
1.38
5.67
1.1
1.1
—
—
—
0
0
194
662
1.47
5.55
1.2
1.3
466.3
204.0
ug/l
0.66
109
349
132
414
1.60
5.52
2.0
1.7
44.2
50.9
pmol/l
0.37
108
349
24756
120665
1.04
5.51
2.1
2.0
—
—
—
0
0
411
1589
1.30
5.51
2.2
2.2
506.4
496.9
min
1.23
312
1195
636
2593
1.23
5.47
1.4
1.5
—
—
—
0
0
266
965
1.38
5.46
1.2
1.2
0.8
0.5
g/l
0.29
12
64
841
3526
1.20
5.44
1.5
1.6
59.3
56.1
%
1.38
517
2279
58
142
2.05
5.36
1.0
1.0
—
—
—
0
0
240
860
1.40
5.31
1.4
1.4
58.0
63.6
%
1.56
202
706
143
462
1.55
5.30
2.6
2.6
36.1
72.3
mg/l
1.45
36
59
264
963
1.37
5.26
1.1
1.1
—
—
—
0
0
368
1415
1.30
5.17
2.1
2.2
1956.5
2000.3
ml
0.25
327
1275
269
988
1.36
5.15
1.0
1.0
—
—
—
0
0
746
3111
1.20
5.14
3.1
3.3
6.9
7.6
nmol/l
0.13
715
3022
18
23
3.92
5.12
1.3
1.3
—
—
—
0
0
1246
5428
1.15
5.07
3.1
3.5
584.4
898.7
u/ml
0.57
1115
4950
553
2242
1.24
5.05
1.2
1.2
60.2
50.3
u/ml
0.23
20
112
354
1361
1.30
5.00
1.1
1.1
1636.4
1455.6
miu/ml
1.98
354
1361
1558
6901
1.13
4.96
5.0
3.7
—
—
—
0
0
71
194
1.83
4.87
1.2
1.2
109.5
110.3
ug/l
0.02
44
123
223
803
1.39
4.84
1.4
1.4
59.0
53.9
%
1.18
181
695
59300
294208
1.04
4.84
4.5
4.1
1.4
1.5
mmol/l
170.65
54422
274643
51
125
2.04
4.75
1.3
1.5
—
—
—
0
0
84
247
1.70
4.56
1.1
1.1
—
—
—
0
0
29
56
2.59
4.53
1.0
1.0
0.3
1.1
u/ml
0.81
22
41
524
2140
1.23
4.52
1.3
1.3
0.8
1.4
u/ml
1.34
259
902
332
1286
1.29
4.49
2.2
2.1
166.3
83.5
ug/min
0.60
82
286
1125
4915
1.15
4.45
1.5
1.4
—
—
—
0
0
633
2639
1.20
4.45
4.0
5.0
59.2
116.8
u/ml
2.45
175
849
59
157
1.88
4.42
2.3
2.3
20.0
18.7
mmol/l
0.16
48
131
1556
6947
1.12
4.41
1.3
1.2
—
—
—
0
0
454
1833
1.24
4.37
1.1
1.2
1.1
1.1
ratio
0.83
144
671
94
289
1.63
4.35
1.3
1.3
27.2
24.0
%
0.34
71
227
71
202
1.76
4.33
3.1
2.0
53.3
60.6
%
0.70
40
133
76
221
1.72
4.31
1.0
1.0
—
—
—
0
0
625
2612
1.20
4.30
1.5
1.6
—
—
—
0
0
37
83
2.23
4.29
1.0
1.0
—
—
—
0
0
53
139
1.91
4.16
1.1
1.1
42.9
109.2
u/l
0.78
40
109
558
2320
1.21
4.08
1.5
1.5
—
—
—
0
0
2125
9693
1.10
4.07
3.0
3.6
514.3
1571.2
u/ml
2.12
1785
8367
344
1358
1.27
4.06
1.3
1.3
—
—
—
0
0
62
173
1.79
4.05
1.1
1.1
1.5
3.1
u/ml
—
5
17
18
28
3.22
4.01
1.1
1.1
140.1
144.3
mmol/24h
0.10
18
28
299
1167
1.28
3.88
1.2
1.2
—
—
—
0
0
39
94
2.08
3.85
1.1
1.2
—
—
—
0
0
146
511
1.43
3.81
1.2
1.3
6.8
6.7
u/ml
0.01
34
119
86
270
1.60
3.72
1.5
1.5
164.5
173.0
mmol/l
0.24
76
241
23
44
2.62
3.70
1.0
1.1
2.0
3.3
mmol/l
1.94
18
30
65
190
1.71
3.68
1.2
1.2
—
—
—
0
0
259
1000
1.30
3.67
1.2
1.2
—
—
—
0
0
28
60
2.34
3.63
1.0
1.0
—
—
—
0
0
205
769
1.34
3.58
1.7
1.7
—
—
—
0
0
1089
4831
1.13
3.52
1.1
1.1
13.0
11.4
au/ml
0.17
46
347
64
189
1.70
3.51
3.0
3.0
104.4
380.4
pmol/l
0.37
19
68
43
112
1.92
3.50
1.0
1.0
0.1
0.1
u/ml
0.06
15
47
156
563
1.39
3.48
1.1
1.2
8.7
6.7
u/ml
0.19
108
400
95
311
1.53
3.48
1.6
1.6
—
—
—
0
0
81
256
1.58
3.45
1.2
1.1
1.7
3.2
umol/24h
0.53
81
256
252
979
1.29
3.44
1.1
1.1
—
—
—
0
0
563
2385
1.18
3.43
1.3
1.3
6.4
6.3
mmol/l
0.22
510
2230
208
788
1.32
3.41
1.3
1.2
39.0
40.6
g/l
0.92
109
424
496
2949
0.84
3.39
1.2
1.2
—
—
—
0
0
232
894
1.30
3.38
3.3
3.5
54.2
51.6
%
1.01
232
856
53
151
1.76
3.31
1.0
1.0
0.4
0.6
u/ml
0.18
46
140
333
1346
1.24
3.30
1.1
1.1
—
—
—
0
0
22
44
2.50
3.29
2.0
2.8
2.7
1.9
mu/l
0.32
22
44
48
133
1.81
3.28
1.3
1.4
1521.6
978.1
u/l
0.18
40
123
121
423
1.43
3.25
1.3
1.3
90.8
70.2
mmol/24h
—
8
11
112
386
1.45
3.24
1.2
1.3
—
20.8
—
0
5
471
1980
1.19
3.17
1.1
1.1
8.2
8.3
iu/ml
0.03
98
532
68
211
1.61
3.15
1.0
1.0
0.2
2.0
u/ml
2.01
45
143
57
169
1.69
3.13
1.0
1.1
21.4
16.7
u/ml
0.21
45
141
196
747
1.31
3.12
1.4
1.4
3.4
2.4
%
0.77
169
623
107
369
1.45
3.10
1.1
1.1
—
—
—
0
0
146
535
1.37
3.03
2.1
2.2
—
—
—
0
0
20
40
2.50
3.01
1.2
1.1
—
—
—
0
0
236
929
1.27
2.97
1.1
1.0
12.0
11.6
u/ml
0.04
35
119
38
101
1.88
2.97
1.0
1.0
0.1
0.0
u/ml
0.47
12
38
196
754
1.30
2.95
1.6
1.6
9.2
8.9
ug/l
0.39
196
754
7
5
7.01
2.89
1.0
1.0
—
—
—
0
0
431
1816
1.19
2.87
1.3
1.3
16.2
13.7
u/l
0.73
398
1683
18
35
2.58
2.86
1.0
1.0
10418.8
13895.8
ng/l
—
9
6
282
1142
1.24
2.81
2.4
2.0
8.3
8.6
%
0.20
270
1119
21
45
2.34
2.78
1.3
1.3
87.7
55.6
e6/l
—
10
37
269
1089
1.24
2.71
2.7
2.7
178.3
141.0
au/ml
0.49
39
142
38
105
1.81
2.68
1.2
1.5
—
—
—
0
0
155
586
1.32
2.67
1.4
1.4
24.3
22.1
%
0.41
131
492
194
758
1.28
2.64
1.3
1.3
3.9
3.4
mmol/l
0.94
176
705
111
400
1.39
2.60
1.4
1.5
6.3
262326.5
nmol/l
2.56
84
345
445
1905
1.17
2.51
1.6
1.7
2036.1
1916.5
ml
0.55
94
451
19
41
2.32
2.50
1.0
1.0
0.1
0.1
u/ml
0.16
14
31
1292
5914
1.10
2.47
1.1
1.1
5.6
5.7
u/ml
0.08
698
3089
996
4501
1.11
2.47
1.3
1.2
—
—
—
0
0
1429
6573
1.09
2.45
1.1
1.1
1.6
1.8
u/ml
0.27
627
2682
234
945
1.24
2.45
1.1
1.1
1.9
8.7
u/ml
1.22
127
552
70
234
1.50
2.44
1.1
1.2
17.0
17.5
g/l
0.18
58
214
90
318
1.42
2.39
1.0
1.1
1.7
5.9
u/ml
1.31
61
251
72
244
1.48
2.36
1.2
1.1
—
—
—
0
0
272
1121
1.22
2.36
2.4
1.9
—
—
—
0
0
79
273
1.45
2.36
1.1
1.1
—
—
—
0
0
170
666
1.28
2.32
1.1
1.1
—
—
—
0
0
170
666
1.28
2.32
1.1
1.1
—
—
—
0
0
170
666
1.28
2.32
1.1
1.1
—
—
—
0
0
169
662
1.28
2.31
1.1
1.2
—
—
—
0
0
14
27
2.60
2.29
1.6
1.3
—
—
—
0
0
8
10
4.01
2.28
1.0
1.0
16.9
13.9
umol/l
—
8
10
422
1817
1.16
2.26
1.2
1.2
—
—
—
0
0
328
1384
1.19
2.24
1.5
1.5
3.1
4.4
%
0.70
67
327
1228
5638
1.09
2.23
1.1
1.1
1.3
1.1
u/ml
0.40
554
2436
286
1193
1.20
2.22
3.3
3.2
7.6
8.1
mg/l
0.61
229
950
113
422
1.34
2.19
5.3
5.0
43.2
44.9
ug/min
0.11
88
328
7
8
4.38
2.18
1.1
1.0
—
—
—
0
0
15
31
2.42
2.17
2.0
2.0
—
—
—
0
0
15
31
2.42
2.17
1.0
1.0
—
—
—
0
0
15
31
2.42
2.17
2.0
2.0
—
—
—
0
0
15
31
2.42
2.17
2.0
2.0
—
—
—
0
0
12
22
2.73
2.14
1.0
1.1
—
—
—
0
0
38
114
1.67
2.10
1.1
1.3
0.6
0.9
umol/24h
0.32
14
54
171
683
1.25
2.04
1.4
1.4
27.4
20.4
%
2.31
162
608
41
127
1.62
2.03
1.6
1.8
1.7
1.6
mpas
0.07
25
75
162
644
1.26
2.01
1.1
1.1
0.5
2.2
u/ml
—
6
27
64
220
1.46
2.01
1.0
1.0
—
—
—
0
0
28
78
1.80
1.99
1.1
1.1
—
—
—
0
0
142
558
1.27
1.95
1.3
1.2
44.7
41.1
mg/l
0.04
107
391
367
2121
0.87
1.93
1.0
1.0
—
—
—
0
0
46
149
1.55
1.91
1.2
1.1
1.1
1.1
u/field
0.30
27
105
131
511
1.28
1.91
2.9
5.6
65.5
53.6
u/l
0.17
46
203
21
54
1.95
1.89
1.2
1.2
—
—
—
0
0
672
3026
1.11
1.88
1.1
1.1
—
—
—
0
0
27
76
1.78
1.87
1.1
1.3
—
—
—
0
0
31
92
1.69
1.82
2.6
2.6
4.4
4.3
mmol/l
0.38
31
87
27
77
1.76
1.81
1.0
1.0
—
—
—
0
0
117
454
1.29
1.80
1.2
1.2
1.5
1.7
mmol/l
1.09
67
276
169
688
1.23
1.75
2.2
2.4
—
—
—
0
0
71
257
1.38
1.73
1.3
1.2
—
—
—
0
0
3168
15161
1.05
1.73
3.1
3.3
60.3
47.9
u/ml
0.62
3026
14682
17
42
2.03
1.71
1.1
1.1
—
—
—
0
0
214
895
1.20
1.70
2.9
1.3
—
—
—
0
0
17397
88585
0.98
1.69
1.5
1.5
—
—
—
0
0
14
32
2.19
1.68
1.0
1.0
0.2
0.3
u/ml
—
7
16
174
716
1.22
1.65
1.3
1.3
35.5
39.7
%
0.68
112
486
17756
90365
0.98
1.64
4.4
4.8
3.2
3.2
ug/l
0.03
15620
81923
32
99
1.62
1.64
1.1
1.2
—
—
—
0
0
15
36
2.09
1.62
1.1
1.1
—
—
—
0
0
94
360
1.31
1.62
1.2
1.3
0.8
1.4
mmol/l
0.99
53
231
578
2610
1.11
1.59
4.1
3.6
45.2
50.2
u/ml
0.23
568
2583
147
597
1.23
1.59
2.7
2.5
—
—
—
0
0
9
16
2.82
1.58
2.7
1.9
—
—
—
0
0
142
871
0.82
1.56
1.8
1.4
—
—
—
0
0
46
157
1.47
1.56
1.5
1.5
—
—
—
0
0
7
12
2.92
1.55
1.0
1.0
—
—
—
0
0
72
267
1.35
1.55
1.3
1.2
—
—
—
0
0
19
51
1.87
1.55
1.0
1.0
3.1
0.4
u/ml
—
10
29
159
656
1.21
1.50
2.4
2.6
110.5
106.3
ng/l
0.12
93
336
35
114
1.54
1.48
1.2
1.2
0.1
0.1
g/l
1.14
24
85
13
123
0.53
1.45
1.0
1.0
0.1
0.2
u/ml
—
8
59
5
7
3.58
1.44
1.0
1.0
—
—
—
0
0
15
38
1.98
1.44
1.0
1.1
0.1
0.6
umol/l
—
8
17
85
329
1.29
1.40
1.0
1.1
0.9
3.4
u/ml
0.69
42
179
1003
5390
0.93
1.40
1.1
1.1
—
—
—
0
0
12
28
2.15
1.40
1.9
2.9
—
—
—
0
0
86
336
1.28
1.33
1.0
1.1
—
—
—
0
0
83
323
1.29
1.33
1.0
1.1
0.6
0.7
u/ml
0.09
49
174
73
280
1.31
1.30
1.1
1.3
5.8
6.3
mmol/l
0.27
32
136
12
29
2.07
1.30
9.2
8.3
6.8
7.7
ug/l
0.62
12
24
98
391
1.26
1.30
1.2
1.2
20.8
20.3
mmol/l
0.58
79
337
29
94
1.54
1.28
1.1
1.1
224.2
297.6
nmol/l
1.38
29
94
13
33
1.97
1.26
1.0
1.1
—
—
—
0
0
21
63
1.67
1.25
5.1
4.9
6.3
6.2
mg/l
0.02
15
47
24
75
1.60
1.23
5.7
5.8
1.1
1.6
mg/l
0.48
19
50
25
79
1.58
1.23
1.0
1.0
—
—
—
0
0
222
963
1.15
1.23
1.1
1.1
—
—
—
0
0
1008
5385
0.94
1.23
1.1
1.1
—
—
—
0
0
344
1537
1.12
1.22
3.4
2.8
—
—
—
0
0
1182
5574
1.06
1.21
1.1
1.1
2.1
2.4
u/ml
0.27
335
1383
53109
264618
1.02
1.21
23.4
14.9
332.5
332.9
g/l
13.39
52639
262655
76
297
1.28
1.21
1.0
1.1
0.5
0.5
u/ml
0.07
40
165
16
45
1.78
1.18
1.1
1.1
76.1
103.4
nmol/24h
1.28
16
45
5
9
2.78
1.16
1.0
1.1
—
—
—
0
0
7
72
0.49
1.16
6.4
6.8
—
—
—
0
0
105
429
1.23
1.16
1.5
1.6
—
—
—
0
0
37
130
1.43
1.15
1.2
1.2
25.2
20.0
u/ml
—
5
28
843
4516
0.93
1.14
3.5
3.5
32.0
38.9
u/ml
1.00
807
4362
15
42
1.79
1.13
1.0
1.1
—
—
—
0
0
572
3107
0.92
1.12
1.4
1.3
—
—
—
0
0
18
54
1.67
1.09
1.3
1.3
—
—
—
0
0
475
2596
0.92
1.09
1.3
1.3
119.0
111.5
pmol/l
0.05
186
756
31
107
1.45
1.07
4.9
5.7
16.6
17.8
mmol/l
0.49
26
100
90
366
1.23
1.06
2.4
2.7
66.2
73.7
pmol/l
0.19
76
321
63
246
1.28
1.04
1.1
1.1
—
—
—
0
0
80
322
1.24
1.04
1.1
1.1
—
—
—
0
0
117
491
1.19
1.02
1.2
1.4
48.8
189.0
titre
—
8
55
65
409
0.80
1.01
5.0
1.2
8.5
7.1
mmol/l
2.27
34
132
44
164
1.34
1.01
1.9
1.7
0.6
0.7
umol/l
0.79
34
128
182
793
1.15
1.01
1.4
1.5
—
—
—
0
0
201
882
1.14
1.00
1.7
1.7
139.5
130.9
au/ml
0.07
25
107
6
12
2.50
0.99
1.0
1.0
21.8
22.1
umol/l
—
6
12
310
1399
1.11
0.98
3.5
2.9
—
—
—
0
0
83
338
1.23
0.98
1.0
1.5
—
44.3
—
0
23
179
1025
0.87
0.98
2.6
3.0
—
—
—
0
0
21
68
1.55
0.98
1.0
1.0
0.1
0.1
u/ml
0.18
14
55
44
165
1.34
0.98
1.6
1.5
—
—
—
0
0
56
218
1.29
0.96
1.1
1.1
17.0
19.2
iu/ml
0.06
17
67
25
85
1.47
0.95
1.2
1.8
—
—
—
0
0
6
13
2.31
0.95
1.2
1.0
—
—
—
0
0
288
1301
1.11
0.92
1.6
1.4
—
—
—
0
0
350
1920
0.91
0.92
1.0
1.0
0.5
0.8
u/ml
0.37
62
257
48
185
1.30
0.90
1.5
1.3
336.6
322.9
umol/24h
0.17
48
185
23
78
1.48
0.89
1.2
1.2
—
—
—
0
0
50
195
1.28
0.87
1.1
1.1
—
—
—
0
0
1405
6734
1.05
0.86
1.5
1.4
143.8
125.8
pmol/l
0.51
1366
6573
53
209
1.27
0.85
1.1
1.1
50.0
31.3
u/ml
—
10
48
53
209
1.27
0.85
1.1
1.1
31.6
24.6
u/ml
—
9
40
43
165
1.30
0.85
1.0
1.1
—
—
—
0
0
6
15
2.00
0.84
1.3
1.1
30.2
31.3
nmol/24h
—
6
15
0
14
0.00
0.83
0.0
1.1
—
—
—
0
0
95
401
1.19
0.82
14.9
5.6
—
—
—
0
0
141
616
1.15
0.80
1.2
1.2
—
—
—
0
0
141
617
1.14
0.79
1.2
1.2
—
—
—
0
0
51
203
1.26
0.78
1.1
1.1
—
—
—
0
0
141
618
1.14
0.78
1.2
1.2
—
—
—
0
0
271
1489
0.91
0.77
1.8
1.9
—
—
—
0
0
54
217
1.25
0.77
3.1
3.2
17.7
10.0
%
0.95
17
65
1076
5146
1.05
0.76
1.3
1.2
—
—
—
0
0
43
272
0.79
0.75
1.2
1.2
—
—
—
0
0
302
1387
1.09
0.74
1.2
1.3
—
—
—
0
0
16
117
0.68
0.72
1.1
1.0
0.1
0.5
u/ml
—
7
52
44
174
1.27
0.72
1.4
1.3
23.6
16.0
pmol/l
0.64
39
145
11
33
1.67
0.70
2.9
2.3
—
—
—
0
0
24
87
1.38
0.70
1.0
1.0
0.1
0.3
u/ml
—
8
18
286
1315
1.09
0.69
1.1
1.1
—
—
—
0
0
89
381
1.17
0.69
1.3
1.4
12.4
11.6
%
0.09
45
193
994
4760
1.05
0.69
1.1
1.1
5.6
4.5
u/ml
0.53
421
1879
167
749
1.12
0.67
1.8
2.0
54.0
32.1
u/l
0.61
145
684
35
136
1.29
0.67
12.8
9.3
170.0
227.3
e6/l
0.22
29
97
55
226
1.22
0.67
1.2
1.2
7.7
9.5
mg/l
0.74
48
210
62
258
1.20
0.66
1.2
1.2
—
—
—
0
0
53
217
1.22
0.66
1.0
1.0
0.2
1.1
u/ml
0.62
19
78
19
67
1.42
0.65
1.1
1.0
0.1
0.2
u/ml
0.16
14
41
37
146
1.27
0.64
1.1
1.0
—
—
—
0
0
372
1738
1.07
0.63
1.4
1.4
5.8
5.5
mmol/l
2.74
349
1644
396
2118
0.94
0.63
1.1
1.1
2.7
4.2
u/ml
0.39
119
550
30
116
1.29
0.60
1.1
1.1
0.0
0.4
mg/l
0.54
25
103
858
4486
0.96
0.60
1.3
1.3
7.3
7.0
mmol/l
1.53
630
3197
6
17
1.77
0.59
1.2
1.1
—
—
—
0
0
41
166
1.24
0.59
1.0
1.1
—
—
—
0
0
73
313
1.17
0.58
3.2
2.4
—
—
—
0
0
311
1672
0.93
0.58
1.2
1.2
—
—
—
0
0
11
35
1.57
0.58
1.0
1.0
—
—
—
0
0
239
1103
1.09
0.57
2.0
2.0
8.4
9.5
mg/l
2.40
190
883
52
217
1.20
0.57
1.0
1.1
1.1
0.9
u/ml
0.14
31
127
6
18
1.67
0.57
1.0
1.0
—
—
—
0
0
18
65
1.39
0.56
1.3
1.2
—
—
—
0
0
77
334
1.15
0.55
1.5
1.6
103.1
116.7
ug/l
0.55
63
273
17
61
1.40
0.54
7.6
8.4
48.3
42.5
%
—
6
37
62
265
1.17
0.53
1.4
1.3
338.4
385.7
mg/24h
—
6
41
50
210
1.19
0.52
1.0
1.1
8.3
7.3
u/ml
0.13
31
146
58
247
1.18
0.52
5.1
4.4
—
—
—
0
0
58
338
0.86
0.50
1.0
1.0
8.9
8.6
mu/l
0.13
49
287
1292
6273
1.03
0.50
4.0
3.1
27.0
26.6
mg/l
0.14
807
3938
40
166
1.21
0.48
1.4
1.1
—
—
—
0
0
11
37
1.49
0.48
1.6
1.3
—
—
—
0
0
19
124
0.77
0.48
1.0
1.0
163.7
163.4
g/l
0.02
19
124
24
94
1.28
0.47
1.0
1.0
—
—
—
0
0
43
181
1.19
0.46
1.1
1.3
—
—
—
0
0
12
42
1.43
0.44
1.0
1.1
883.3
2306.4
titre
2.93
12
42
105
582
0.90
0.44
1.1
1.1
—
—
—
0
0
35
145
1.21
0.44
1.1
1.3
—
19339.8
—
0
10
0
9
0.00
0.43
0.0
1.0
—
—
—
0
0
14
51
1.37
0.43
1.0
1.1
—
—
—
0
0
72
319
1.13
0.42
1.3
1.3
98.4
278.4
u/l
0.61
51
230
256
1205
1.06
0.41
1.7
1.8
—
—
—
0
0
103
567
0.91
0.39
2.4
1.7
1.9
3.8
ug/l
1.15
61
345
9
33
1.37
0.39
1.0
1.0
—
—
—
0
0
330
1571
1.05
0.37
2.0
2.1
2.3
2.4
ug/l
0.11
267
1325
5
39
0.64
0.37
1.6
1.2
—
—
—
0
0
5
39
0.64
0.37
1.6
1.2
—
—
—
0
0
21
84
1.25
0.37
5.0
7.4
11.7
12.5
ml/dl
0.30
16
68
43
186
1.16
0.36
1.1
1.1
2.4
1.4
u/ml
0.32
32
134
68
304
1.12
0.36
1.5
1.4
71.6
71.6
%
0.00
54
257
457
2382
0.96
0.35
1.2
1.2
—
—
—
0
0
615
2976
1.03
0.34
1.3
1.4
12.1
11.8
mmol/l
0.34
197
607
10
36
1.39
0.33
1.0
1.1
—
—
—
0
0
1541
7874
0.98
0.33
1.1
1.1
—
—
—
0
0
149
797
0.94
0.31
1.1
1.2
—
—
—
0
0
169
795
1.06
0.31
1.5
1.3
—
—
—
0
0
919
4485
1.03
0.31
1.1
1.1
6.0
5.0
u/ml
0.58
416
1862
5062
25082
1.01
0.31
1.4
1.4
—
—
—
0
0
904
4414
1.03
0.30
1.6
1.6
—
—
—
0
0
906
4649
0.98
0.29
1.4
1.3
3.7
3.8
ug/l
0.05
801
4174
11
71
0.78
0.28
5.1
5.5
0.2
0.2
mmol/l
0.26
11
71
83
383
1.09
0.27
1.4
1.3
119.3
152.9
titre
—
6
30
38
215
0.88
0.27
2.8
2.2
—
—
—
0
0
25
146
0.86
0.27
1.0
1.1
—
—
—
0
0
73
398
0.92
0.26
9.3
9.3
0.4
0.4
umol/l
0.21
62
368
418
2164
0.97
0.26
1.1
1.1
—
—
—
0
0
86
465
0.93
0.26
6.2
7.6
—
—
—
0
0
10
63
0.79
0.22
2.0
1.3
1.8
2.3
mmol/24h
—
10
63
8
53
0.76
0.22
1.0
1.1
—
—
—
0
0
21
90
1.17
0.22
1.0
1.1
5.7
5.3
mmol/l
0.24
15
61
51
233
1.10
0.22
1.1
1.1
—
—
—
0
0
18
76
1.19
0.22
1.4
1.7
206.8
98.5
ug/l
0.79
13
42
71
330
1.08
0.21
1.7
1.7
1.7
1.7
mg/l
0.02
63
275
90
423
1.07
0.20
3.1
3.0
—
—
—
0
0
415
2135
0.97
0.20
1.1
1.1
2.4
2.8
u/ml
0.11
156
622
40
182
1.10
0.19
1.8
1.8
1.0
0.7
%
0.39
29
142
121
637
0.95
0.19
6.7
8.3
—
—
—
0
0
36
163
1.11
0.19
1.0
1.1
0.1
12.4
u/ml
0.51
15
73
75
400
0.94
0.18
1.0
1.0
—
—
—
0
0
359
1845
0.97
0.17
1.4
1.4
27.1
32.8
nmol/l
3.40
319
1711
47
217
1.08
0.17
1.7
1.6
—
—
—
0
0
90
475
0.95
0.16
5.9
5.5
—
—
—
0
0
12
50
1.20
0.16
1.4
1.4
0.8
0.6
u/field
—
5
28
785
3868
1.02
0.16
1.1
1.0
0.8
0.4
u/ml
0.77
199
818
94
448
1.05
0.15
2.8
2.7
2026.9
1630.6
u/l
0.20
84
405
7
44
0.80
0.15
1.0
1.0
—
—
—
0
0
7
45
0.78
0.15
1.0
1.2
—
—
—
0
0
19
85
1.12
0.12
1.1
1.3
—
—
—
0
0
175
902
0.97
0.12
1.2
1.2
—
—
—
0
0
32
148
1.08
0.12
1.0
1.1
0.1
10.3
u/ml
0.52
14
73
55
291
0.95
0.12
1.5
1.6
—
—
—
0
0
252
1234
1.02
0.11
1.2
1.3
—
—
—
0
0
352
1795
0.98
0.11
6.2
6.6
—
—
—
0
0
610
3014
1.01
0.11
1.2
1.1
—
—
—
0
0
199
973
1.02
0.10
1.2
1.1
—
—
—
0
0
20
91
1.10
0.10
1.2
1.1
1.4
8.3
mmol/l
0.54
13
59
331
1629
1.02
0.10
1.9
2.0
3.3
3.8
ug/l
0.50
288
1436
915
4626
0.99
0.10
1.1
1.1
2.6
3.0
u/ml
0.67
360
2412
5
23
1.09
0.10
1.4
2.0
10.0
16.1
%
—
5
23
47
247
0.95
0.09
1.2
1.5
0.3
0.2
umol/l
0.37
16
86
5
31
0.81
0.08
1.0
1.0
—
—
—
0
0
1257
6339
0.99
0.08
1.3
1.3
—
—
—
0
0
221
1087
1.02
0.08
1.0
1.0
—
—
—
0
0
66
342
0.97
0.07
2.7
2.6
—
—
—
0
0
10
56
0.89
0.06
1.0
1.0
407.8
353.9
umol/l
—
5
28
446
2212
1.01
0.06
1.9
1.9
3.9
3.7
mg/l
0.43
415
2116
30
158
0.95
0.06
1.4
1.3
1.6
1.7
mg/l
0.04
25
132
61
315
0.97
0.06
3.2
2.9
1.6
1.3
mg/l
0.36
45
214
107
525
1.02
0.05
1.4
1.4
—
—
—
0
0
55
283
0.97
0.04
1.0
1.0
3.5
3.6
kpa
0.10
48
246
14
65
1.08
0.04
1.6
1.2
4.6
5.5
mg/l
0.09
14
60
160
792
1.01
0.03
1.8
1.8
—
—
—
0
0
90
458
0.98
0.03
2.2
2.3
3.7
3.8
ug/l
0.08
34
153
25
120
1.04
0.03
1.0
1.0
—
—
—
0
0
38
196
0.97
0.03
1.1
1.1
—
—
—
0
0
7729
38659
1.00
0.03
1.2
1.3
—
—
—
0
0
213
1058
1.01
0.02
1.7
1.6
—
—
—
0
0
57
290
0.98
0.01
1.0
1.0
—
—
—
0
0
22
114
0.97
0.01
1.0
1.0
—
—
—
0
0
145
721
1.01
0.01
6.5
8.5
—
—
—
0
0
57
289
0.99
0.01
1.0
1.0
7.1
7.2
kpa
0.09
50
253
11
55
1.00
0.00
1.3
1.3
—
—
—
0
0
22
113
0.97
0.00
1.0
1.0
—
—
—
0
0
25
125
1.00
0.00
1.1
1.2
—
—
—
0
0
57
287
0.99
0.00
1.0
1.0
-2.4
-2.1
mmol/l
0.08
12
66
11
53
1.04
0.00
1.0
1.1
—
—
—
0
0
14
69
1.02
0.00
1.1
1.1
0.1
0.2
g/l
—
6
21
12
61
0.98
0.00
1.2
1.2
22.1
30.2
mg/l
1.03
12
54
22
112
0.98
0.00
1.0
1.0
—
—
—
0
0
22
112
0.98
0.00
1.0
1.0
—
—
—
0
0
20
102
0.98
0.00
1.1
1.0
0.1
0.2
u/ml
0.09
11
59
28
143
0.98
0.00
7.9
10.8
—
—
—
0
0
22
111
0.99
0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
38
0.92
0.00
1.1
1.0
—
—
—
0
0
5
26
0.96
0.00
1.0
1.0
189.0
157.3
g/l
—
5
26

Mortality – FinRegistry

Association

Association between endpoint KRA_PSY_ANYMENTAL and mortality.

Females

Parameter HR [95% CI] p-value
KRA_PSY_ANYMENTAL 2.698 [2.51, 2.9] < 0.001
Birth year 0.983 [0.98, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 143420 out of 609488 females with KRA_PSY_ANYMENTAL died.

Males

Parameter HR [95% CI] p-value
KRA_PSY_ANYMENTAL 3.194 [2.94, 3.48] < 0.001
Birth year 0.979 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 121373 out of 527573 males with KRA_PSY_ANYMENTAL died.

Mortality risk

Mortality risk for people of age

years, who have KRA_PSY_ANYMENTAL.

N-year risk Females Males
1 0.117% 0.245%
5 0.699% 1.727%
10 1.767% 4.522%
15 3.293% 8.573%
20 5.577% 14.132%

Relationships between endpoints

Index endpoint: KRA_PSY_ANYMENTAL – Any mental disorder

GWS hits: 45

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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