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Seminoma of testis

C3_TESTIS_SEMINOMA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only males

226837

2. Check conditions

None

226837

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C62.01&, C62.11&, C62.91&
  • Hospital discharge: ICD-9 186A
  • Cause of death: ICD-10 C62.01&, C62.11&, C62.91&
  • Cause of death: ICD-9 186A
  • Cancer registry: Topography ICD-O-3 C62
  • Cancer registry: Morphology ICD-O-3 9061
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

362

4. Check minimum number of events

None

362

5. Include endpoints

None

362

6. Filter based on genotype QC (FinnGen only)

362

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF9

Similar endpoints

List of similar endpoints to Seminoma of testis based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 362 - 362
Unadjusted period prevalence (%) 0.16 - 0.16
Median age at first event (years) 37.93 - 37.93

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
328
Matched controls
3280
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C62.11
ICD-10 Finland
Malignant tumor of the descending testicle, seminoma
+∞
309.6
246
*
9061/3-C62.9
ICD-O-3
Seminoma, NOS, of testis, NOS
+∞
264.9
217
*
KFC00
NOMESCO Finland
Unilateral orchiectomy
581.9
255.8
224
12
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
444.8
197.7
180
9
JN4BD
NOMESCO Finland
Extensive body CT
14.8
74.6
137
151
9061/3-C62.1
ICD-O-3
Seminoma, NOS, of descended testis
+∞
63.6
59
*
C62.10
ICD-10 Finland
Malignant tumor of the descending testicle, no histological verification
351.9
59.3
58
*
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
20.7
57.5
88
57
C62.1
ICD-10 Finland
Malignant neoplasm: Descended testis
+∞
49.2
46
*
C62.91
ICD-10 Finland
Malignant tumor in unspecified location in testis, seminoma
+∞
41.5
39
*
KFH50
NOMESCO Finland
Insertion of prosthetic replacement for testis
159.9
40.8
42
*
130
Kela drug reimbursment
Malignant tumour
8.4
37.6
90
141
C62.01
ICD-10 Finland
Malignant tumor of the non-descending testicle, seminoma
+∞
36.1
34
*
JN4AD
NOMESCO Finland
Body CT examination
8.9
33.6
76
107
A03FA01
ATC
metoclopramide; systemic, rectal
5.8
32.7
107
254
7511
FHL
Orchidectomy (unilateral), also includes funicularectomy
126.0
32.3
34
*
18699
ICD-8 Finland
Malignant neoplasm of testis
331.3
30.3
30
*
C62.12
ICD-10 Finland
Malignant tumor of the descending testicle, embryonic carsinoma, teratocarcinoma or coriocarsinoma
88.5
29.3
32
*
C62.99
ICD-10 Finland
Malignant tumor in unspecified location in testis,other or undetermined histology
306.3
28.2
28
*
C62.90
ICD-10 Finland
Malignant tumor in unspecified location in testis, no histological verification
306.3
28.2
28
*
C62.19
ICD-10 Finland
Malignant tumor of the descending testicle, other or undetermined histology
109.7
28.2
30
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.5
25.1
187
908
JN3BD
NOMESCO Finland
Extensive abdominal CT
5.8
25.0
77
164
121
Kela drug reimbursment
Severe hypofunction of sexual glands
22.1
23.6
34
17
C62.00
ICD-10 Finland
Malignant tumor of the non-descending testicle, no histological verification
+∞
23.2
22
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
24.5
18.0
25
11
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.0
17.9
138
640
1869A
ICD-9 Finland
Malignant neoplasm of testis, Other and unspecified testis[NEOPL MAL TESTIS (SCROTALIS),SEMINOMA]
+∞
17.9
17
*
JN3AD
NOMESCO Finland
Abdominal CT examination
5.4
17.6
55
117
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
8.5
17.2
38
50
A04AA02
ATC
granisetron; systemic, transdermal
7.0
15.3
38
60
L03AA02
ATC
filgrastim; parenteral
14.1
15.0
25
19
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
22.3
14.9
21
10
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
15.1
14.8
24
17
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
4.4
14.6
55
142
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
14.1
106
470
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.7
13.3
63
200
H02AB02
ATC
dexamethasone; systemic
4.5
12.3
44
108
D29.2
ICD-10 Finland
Benign neoplasm: Testis
48.5
12.0
14
*
E29.1
ICD-10 Finland
Testicular hypofunction
7.4
11.6
27
39
C62.9
ICD-10 Finland
Malignant neoplasm: Testis, unspecified
+∞
11.5
11
*
9085/3-C62.9
ICD-O-3
Mixed germ cell tumor of testis, NOS
124.2
11.5
12
*
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
124.2
11.5
12
*
C62
ICD-10 Finland
Malignant neoplasm of testis
+∞
10.5
10
*
Y78
ICPC
Malign neopl male genital other
+∞
10.5
10
*
ZXE00
NOMESCO Finland
One hour or less
2.3
10.2
126
709
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
41.4
10.0
12
*
C62.92
ICD-10 Finland
Malignant tumor in unspecified location in testis, embryonic carsinoma, teratocarcinoma or coriocarsinoma
102.9
9.5
10
*
C62.0
ICD-10 Finland
Malignant neoplasm: Undescended testis
+∞
9.4
9
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.8
9.2
61
244
WX320
NOMESCO Finland
Spinalanesthesy
2.6
9.0
75
341
N46
ICD-10 Finland
Male infertility
5.2
8.9
27
56
N02AA05
ATC
oxycodone; systemic
3.0
8.9
54
204
KFA00
NOMESCO Finland
Exploration of testis
28.4
8.5
11
*
A04AA01
ATC
ondansetron; systemic, rectal
5.0
8.5
26
55
7513
FHL
Test prosthesis installation
92.3
8.5
9
*
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
11.2
8.4
15
14
C62.02
ICD-10 Finland
Malignant tumor of the non-descending testicle, embryonic carsinoma, teratocarcinoma or coriocarsinoma
+∞
8.4
8
*
1869X
ICD-9 Finland
Malignant neoplasm of testis, Other and unspecified testis[NEOPL MAL TESTIS (SCROTALIS),EI HIST VAHV]
+∞
8.4
8
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
11.2
7.9
14
13
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
7.8
111
649
D70.82
ICD-10 Finland
Drug-induced neutropenia
10.4
7.6
14
14
N02BE01
ATC
paracetamol; systemic, rectal
2.1
7.6
263
2146
2395A
ICD-9 Finland
Neoplasm of unspecified nature, Other genito-urinary organs
81.9
7.4
8
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
6.9
109
660
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.6
6.8
22
50
PJD53
NOMESCO Finland
Block dissection of aortic lymph nodes
40.9
6.8
8
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.1
6.6
15
22
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
5.0
6.3
19
40
Y28
ICPC
Limited function/disability (Y)
18.4
6.3
9
5
Z85.4
ICD-10 Finland
Personal history of malignant neoplasm of genital organs
+∞
6.3
6
*
9063/3-C62.9
ICD-O-3
Spermatocytic seminoma of testis, NOS
+∞
6.3
6
*
YJ1AD
NOMESCO Finland
CT examination of abdomen for dose design of radiotherapy
27.2
6.3
8
*
ZX120
NOMESCO Finland
Intravenous
3.0
6.2
35
125
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.7
6.1
42
169
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.5
6.0
27
83
WZC30
NOMESCO Finland
Teaching
2.5
6.0
48
214

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_TESTIS_SEMINOMA – Seminoma of testis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).